re: studies and data showing the connection between trauma and symptomology
- Dear List,
Please find some studies and research below.
This may be heavy for survivors to read.
Trauma immunological studies of abuse survivors
Antinuclear antibodies and thyroid function in sexually abused girls.- De
Bellis MD, Burke L, Trickett PK, Putnam FW J Trauma Stress 1996 Apr;
9(2):369-78 "14 sexually abused and 13 control girls, ages 8-15 years...a
significantly higher incidence of plasma antinuclear antibody titers was seen
in abused subjects when compared with the frequency of positive antinuclear
antibody titers in a sample of 22 adult healthy female volunteers, ages 20-58
years. These findings suggest that sexually abused girls may show evidence of
an alteration in normal immune homeostatic function."
Phenotype of blood lymphocytes in PTSD suggests chronic immune
activation.Wilson SN, van der Kolk B, Burbridge J, Fisler R, Kradin R
Psychosomatics 1999 May-Jun;40(3):222-5 - "Peripheral blood lymphocytes (PBL)
of patients with PTSD associated with a history of childhood sexual abuse
were examined for changes in immune phenotype.... These findings suggest the
presence of increased lymphocyte activation in the PBL of patients with PTSD."
Suppression of cellular immunity in men with a past history of posttraumatic
stress disorder. Kawamura N, Kim Y, Asukai N Am J Psychiatry 2001 Mar;
158(3):484-6 - "The number of lymphocytes, number of T cells, NK cell
activity, and total amounts of IFN-gamma and IL-4 were significantly lower in
the 12 men with a past history of PTSD... PTSD leaves a long-lasting
immunosuppression and has long-term implications for health."
Human immunodeficiency virus-infected adolescents: The first 50 patients in a
New York City program. Futterman D, Hein K, Reuben N, Dell R, Shaffer N
Pediatrics 1993 Apr;91(4):730-5 - "HIV-positive males were more likely than
HIV-negative males to have engaged in anal intercourse and to report a
history of sexual abuse."
The Spectrum of Dissociative Disorders: An Overview of Diagnosis and
Treatment by Joan A. Turkus, M.D. "Researchers and clinicians believe that
dissociation is a common, naturally occurring defense against childhood
trauma. Children tend to dissociate more readily than adults. Faced with
overwhelming abuse, it is not surprising that children would psychologically
flee (dissociate) from full awareness of their experience." The dissociative
spectrum (Braun, 1988) extends from normal dissociation to poly-fragmented
DID. All of the disorders are trauma-based, and symptoms result from the
habitual dissociation of traumatic memories....The dissociated memory is
alive and active--not forgotten, merely submerged (Tasman & Goldfinger,
1991). Major studies have confirmed the traumatic origin of DID (Putnam,
1989, and Ross, 1989), which arises before the age of 12 (and often before
age 5) as a result of severe physical, sexual, and/or emotional abuse."