Loading ...
Sorry, an error occurred while loading the content.

Blood xfusions ref #3

Expand Messages
  • Lorraine Johnston
    Ann Intern Med 1993 Jul 1;119(1):8-15 Transfusion history and cancer risk in older women. Cerhan JR, Wallace RB, Folsom AR, Potter JD, Munger RG, Prineas RJ
    Message 1 of 1 , Mar 9, 1998
    • 0 Attachment
      Ann Intern Med 1993 Jul 1;119(1):8-15

      Transfusion history and cancer risk in older women.

      Cerhan JR, Wallace RB, Folsom AR, Potter JD, Munger RG, Prineas RJ

      University of Minnesota School of Public Health, Minneapolis.

      OBJECTIVE: To test the hypothesis that history of blood transfusion is
      associated with an increased incidence of cancer in
      older women. DESIGN: Prospective cohort study. SETTING: General
      community in the state of Iowa. PARTICIPANTS:
      Random sample of 37,337 cancer-free Iowa women ages 55 to 69
      years. MEASUREMENTS: Transfusion history was
      assessed with a mailed questionnaire completed in January 1986.
      Cancer incidence in 5 years was ascertained by a
      population-based cancer registry. RESULTS: Women who had ever
      received a blood transfusion were at an increased risk for
      non-Hodgkin lymphoma (relative risk (RR) = 2.20; 95% CI, 1.35 to 3.58)
      and kidney cancer (RR = 2.53; CI, 1.34 to 4.78).
      The relative risks for these cancers were greater with decreasing time
      from first transfusion. No increased risk occurred for
      cancers of the breast, lung, uterine corpus, ovary, pancreas, colon,
      rectum, skin (melanoma), or for all cancers considered
      together. CONCLUSION: These findings suggest that previous blood
      transfusion may be a risk factor for non-Hodgkin
      lymphoma and kidney cancer but is not associated with the most
      common neoplasms.
    Your message has been successfully submitted and would be delivered to recipients shortly.