Re: [new_distillers] methanol toxicity
- Thanks for this, good summary. Add that you don't have to drink it,
it's absorbed through the skin. Which makes this recent suggestion
from the Distillers list maybe not such a brilliant idea:
>Also some of my older clients are keeping the methanol from eachKeith
>brew, and combining it with a menthalatum mix from the Health Food
>shop, and rubbing it on their arthritic joints.
>The fatal dose of methanol is 60 to 250ml. Death depends on the sizeand combining it with a menthalatum mix from the Health Food shop, and
>of the individual, their general health and stomach contents. The
>exposure limit is 200ppm. The highly lethal nature of methanol
>(compared to ethanol) has not been fully researched, but it is
>believed to be the result of the byproducts of metabolism, which turn
>methanol into formic acid and formaldehyde, and formaldehyde has been
>proven to have selective injurious effects on retal cells- this is
>the reason for it's ability to cause blindness.
> Methanol is metabolized and excreted at a rate about one-fifth
>that of ethanol, and a single dose may take up to 4 days to leave the
>body (provided the drinker isn't already dead)
> Symptoms fom acute poisoning of a moderate dose- Severe headache,
>dizziness, nausea and vomiting, and central nervous system
>depression. Vision may fail temporarily or permanently after 2-6
>days. In higher doses the above occurs much faster and turn into
>rapid shallow breathing, blood pressure falling, dilation of pupils
>blurring of vision, cyanosis. More than 25% of those who reach this
>level, even in a hospital, still die.
> Chronic poisoning tends to result in visual imparement as the
>first symptom. The only treatment from chronic poisoning is to halt
> Treating acute cases must be done within 2 hours of ingestion:
>give syrup of ipacac. Lavage thoroughly with 2-4L of tap water with
>sodium bicarbonate (20G/L) added. This is to treat acidosis of the
> Antidote: Give ethanol, 50%, 1.5ml per kilo of body weight, orally,
>diluted to no more than a 5% solution, followed by 0.5-1ml/kg every 2
>hours orally for 4 days. ethanol interferes with the absorbtion of
>methanol by the body and allows it to be excreted with less damaging
>effects. Also give up to 4 litres of water daily to maintain
>adequate urine output. Control delirium by giving 10mg valium slowly
>by injection in order to prevent respiratory depression.
> Prognosis:in acute methanol poisoning approx 50% do not recover.
>Visual imparement will show no improvement after 1 week.
>Looking up medical and drug testing labs in the phonebook will help
>you find someplace to send a sample of the stuff your making (say you
>found it in a friend's room and your worried about what he's
>drinking) to see how clean it is.
rubbing it on their arthritic joints.