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  • Bombay Leprosy Project
    ** *BLP News** * * * *Can leprosy diagnosis be done serologically and predicted?* * * How leprosy can be diagnosed serologically and the role of new diagnostic
    Message 1 of 11 , Apr 11, 2013
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      BLP News


      Can leprosy diagnosis be done serologically and predicted?

       

      How leprosy can be diagnosed serologically and the role of new diagnostic kits in predicting the diagnosis was the topic of discussion at the academic meeting held at the Main Referral Centre, Bombay Leprosy Project, Chunabhatti on 30-3-2013.

       

      Dr V V Pai, Director BLP, while introducing the topic of Serological diagnosis of leprosy using Rapid Diagnostic Kits (RDK) mentioned that BLP has been holding such academic meetings and seminars by based on newer studies and review of literature published in the academic for a and that such meetings help in understanding the disease better and as well to improve clinical care and services to leprosy patients.

       

      Dr Prachi Srivastava, a PG Resident in Dermatology from the local city medical college reviewed the published studies dealing with RDK based on using Natural dissacharide antigens and LID-1 protein antigen while presenting the findings of the studies conducted in Brazil and China. The test kits have been developed by Infectious Disease Research Institute, USA. There is no single diagnostic test for leprosy and the diagnosis essentially remains clinical.

      As per the studies the sequencing of entire M leprae genome & identification of new antigens have raised the possibility of wider use of serological tests in diagnosis, treatment, follow up & control of leprosy. Antibodies of IgM and IgG isotypes against the NDO glycolipid and the LID-1 protein respectively are detected.

      The specificity of RDT has been carefully evaluated and nearly all sera from active MB patients are positive (87% acc to the study by IDRI). However its aptitude to diagnose PB leprosy is inconsistent (20% acc to the same study). The test is likely to be useful in:

       

      1.     Diagnosis of suspect cases who lack cardinal signs and also in about 30% of MB cases the tell tale anesthetic skin lesions and clearly enlarged peripheral nerves are absent during early stages of the clinical disease, making this category difficult to diagnose.

       

      2.     Predicting disease in contacts of patients. The developers of this test expect this test to detect infections as much as one year before the symptoms appear clinically.

            

      Post Graduate students in Dermatology, Medical Officers, Paramedical staff, Interns of Masters in Health Administration and Research Collaborators formed the audience.

       

      We are grateful to all our donors, friends and well wishers for the continued support in reaching services to poor and needy leprosy patients and research work contributing in improved patient care activities.

       



      Dr Prachi S, PG Resident of Dermatology, MGM Medical College presenting at the meeting

       



      Interns of MHA presenting at the meeting

       

       

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    • Bombay Leprosy Project
      Dear Sir / Madam, Greetings from Bombay Leprosy Project (BLP)! Please find enclosed BLP News which will be of interest to you. We are thankful to you and the
      Message 2 of 11 , Dec 19, 2013

      Dear Sir / Madam,

      Greetings from Bombay Leprosy Project (BLP)!

      Please find enclosed BLP News which will be of interest to you.

      We are thankful to you and the beneficiaries are also grateful to you for your continued support.

      With kind regards

      Dr V V Pai
      Director

      Encl: BLP News









    • Bombay Leprosy Project
      Dear Sir / Madam, Greetings from Bombay Leprosy Project (BLP)! Please find enclosed BLP News on Anti Leprosy Week Programme which will be of interest to you.
      Message 3 of 11 , Mar 11, 2014


      Dear Sir / Madam,

      Greetings from Bombay Leprosy Project (BLP)!

      Please find enclosed BLP News on Anti Leprosy Week Programme w
      hich will be of interest to you.
       

      We are thankful to you and the beneficiaries are also grateful to you for your continued support.

      With kind regards

      Dr V V Pai
      Director

      Encl: BLP News





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