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16213Re: [jacksongenealogy] Re: Cherokee Blood in Jackson County

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  • Chris Roberts
    Sep 21 12:09 AM
      HI Karl,
      Yes, Karl estimates have been made by the scientific community, but it depends on which area of the mitochondria.  The control region has a faster mutation rate and reflects newer mutations, thus it is more likely to be useful for genealogical purposes.  The coding region mutates slower and is the region used to determine haplogroups (http://www.familytreedna.com/faq/answers.aspx?id=10#2137.)    Scientific papers can differ on the average mutation rate, depending on the methodology used as well as other factors.  Since I am not smart enough to determine which rate might be correct, I have included a link to “The Mutation Rate in the Human mtDNA Control Region” which addresses the mutation rate of the control region.  Further, a search for MTDNA mutation rate will produce numerous results.
      Hopefully, others will have a better answer.
       From: Karl Plenge
      Sent: Friday, September 20, 2013 5:50 PM
      Subject: Re: [jacksongenealogy] Re: Cherokee Blood in Jackson County

      Question for those who know more about DNA testing than I do (which would be almost anyone):  As mtDNA is passed down generally unchanged from mother to daughter, then the only source of changes would be mutations.  Has anyone in the scientific community made an estimate of how many generations pass (on average) between mutations?
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