Loading ...
Sorry, an error occurred while loading the content.
 

Kidney can be target of pathology in Crohn's disease

Expand Messages
  • Sarah Krein
    Kidney can be target of pathology in Crohn s disease (25 December 2002) NEW YORK (Reuters Health) - Interstitial nephritis with renal failure appears to be
    Message 1 of 1 , Dec 26, 2002
      Kidney can be target of pathology in Crohn's disease (25 December 2002)
      NEW YORK (Reuters Health) - Interstitial nephritis with renal failure
      appears to be associated with Crohn's disease in patients who have not used
      mesalamine, French researchers report.

      Dr. H?l?ne Beaufils from Piti? Hospital Paris, and colleagues note that
      reports of interstitial nephritis with renal failure have been reported in
      patients with Crohn's disease who had been treated with mesalamine.

      To investigate whether Crohn's disease and renal failure were associated in
      the absence of mesalamine treatment, the researchers studied four patients
      with severe interstitial nephritis. These patients had been diagnosed with
      renal failure before or at the same time they were diagnosed with Crohn's
      disease and had not been treated with mesalamine.

      Three of the patients progressed to endstage renal failure, Dr. Beaufils'
      team reports in the November issue of Gastroenterology. "Our results show
      that the kidney can be an extraintestinal target of Crohn's disease," they
      conclude.

      They add that "several unanswered questions remain concerning the frequency
      of interstitial nephritis in patients with Crohn's disease, as well as the
      exact role of mesalamine in the development of chronic interstitial
      nephritis."

      Gastroenterology 2002;123:1436-1440.
    Your message has been successfully submitted and would be delivered to recipients shortly.