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Researchers find cancer-inhibiting compound under the sea

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  • brsidharta
    Researchers find cancer-inhibiting compound under the sea http://news.ufl.edu/2008/08/07/marine/ Filed under Research, Health, Environment, Florida on
    Message 1 of 8 , Aug 14, 2008
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      Researchers find cancer-inhibiting compound under the sea

      http://news.ufl.edu/2008/08/07/marine/
      Filed under Research, Health, Environment, Florida on Thursday, August
      7, 2008.GAINESVILLE, Fla.

      - University of Florida College of Pharmacy researchers have discovered
      a marine compound off the coast of Key Largo that inhibits cancer cell
      growth in laboratory tests, a finding they hope will fuel the
      development of new drugs to better battle the disease.

      The UF-patented compound, largazole, is derived from cyanobacteria that
      grow on coral reefs. Researchers, who described results from early
      studies today (Aug. 7) at an international natural products scientific
      meeting in Athens, Greece, say it is one of the most promising they've
      found since the college's marine natural products laboratory was
      established three years ago.

      An initial set of papers in the Journal of the American Chemical Society
      also has garnered the attention of other scientists, and the lab is
      racing to complete additional research. The molecule's natural chemical
      structure and ability to inhibit cancer cell growth were first described
      in the journal in February and the laboratory synthesis and description
      of the molecular basis for its anticancer activity appeared July 2.

      "It's exciting because we've found a compound in nature that may one day
      surpass a currently marketed drug or could become the structural
      template for rationally designed drugs with improved selectivity," said
      Hendrik Luesch, an assistant professor in UF's department of medicinal
      chemistry and the study's principal investigator.

      Largazole, discovered and named by Luesch for its Florida location and
      structural features, seeks out a family of enzymes called histone
      deacetylase, or HDAC. Overactivity of certain HDACs has been associated
      with several cancers such as prostate and colon tumors, and inhibiting
      HDACs can activate tumor-suppressor genes that have been silenced in
      these cancers.

      Although scientists have been probing the depths of the ocean for marine
      products since the early 1960s, many pharmaceutical companies lost
      interest before researchers could deliver useful compounds because
      natural products were considered too costly and time-consuming to
      research and develop.

      Many common medications, from pain relievers to cholesterol-reducing
      statins, stem from natural products that grow on the earth, but there is
      literally an ocean of compounds yet to be discovered in our seas. Only
      14 marine natural products developed are in clinical trials today,
      Luesch said, and one drug recently approved in Europe is the first-ever
      marine-derived anticancer agent.

      "Marine study is in its infancy," said William Fenical, a distinguished
      professor of oceanography and pharmaceutical sciences at the University
      of California, San Diego. "The ocean is a genetically distinct
      environment and the single, most diverse source of new molecules to be
      discovered."

      The history of pharmacy traces its roots back thousands of years to
      plants growing on Earth's continents, used by ancient civilizations for
      medicinal purposes, Fenical added. Yet only in the past 30 years have
      scientists begun to explore the organisms in Earth's oceans, he said.
      Fewer than 30 labs exist worldwide, and research dollars have only
      become available in the past 15 years.

      HDACs are already targeted by a drug approved for cutaneous T-cell
      lymphoma manufactured by the global pharmaceutical company Merck & Co.
      Inc. However, UF's compound does not inhibit all HDACs equally, meaning
      a largazole-based drug might result in improved therapies and fewer side
      effects, Luesch said.

      Since 2006, Luesch and his team of researchers have screened
      cyanobacteria provided by collaborator Valerie Paul, head scientist at
      the Smithsonian Marine Station in Fort Pierce. They check the samples
      for toxic activity against cancer cells and last year encountered one
      exceptionally potent extract - the one that ultimately yielded
      largazole.

      To conduct further biological testing on the compound, Luesch and his
      team have been collaborating with Jiyong Hong, an assistant professor in
      the department of chemistry at Duke University, to replicate its natural
      structure and its actions in the laboratory.

      Luesch said that within the next few months he plans to study whether
      largazole reduces or prevents tumor growth in mice.

      Luesch has several other antitumor natural products from Atlantic and
      Pacific cyanobacteria in the pipeline.

      "We have only scratched the surface of the chemical diversity in the
      ocean," Luesch said. "The opportunities for marine drug discovery are
      spectacular."





      boy rahardjo sidharta
      faculty of biotechnology
      atma jaya yogyakarta university
      jl. babarsari 44
      yogyakarta-55281
      indonesia
      e-mail: <brsidharta@...> or
      <b_rasidh@...>
      http://brsidharta/wordpress.com
      http://brsidharta.edublogs.org

      founder: mailing list [Indonesia_HAB@yahoogroups.com],
      [kabiogama81@yahoogroups.com],
      [dyno_cyst_rg@yahoogroups.com]
      Yayasan Gema Mitra Bahari (GeMaRi) Yogyakarta
      ____________________________________________________________________________
      _____
      Dibuka pendaftaran Program Magister dan Double Degree Pascasarjana UAJY
      (MM - MTF atau sebaliknya; M.Hum - MTF; M.Hum - MM; MTS - MM dan MTArs
      (Digital)).
      Penerimaan mahasiswa setiap September dan Januari.
    • brsidharta
      Dear men-temen, Saya sangat senang bisa ikut workshop microalgae di Biotek LIPI, Cibinong yg diselenggarakan oleh Ibu Dr. Dwi Susilaningsih bersama rekannya
      Message 2 of 8 , Aug 14, 2008
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        Dear men-temen,

        Saya sangat senang bisa ikut workshop microalgae di Biotek LIPI, Cibinong yg
        diselenggarakan oleh Ibu Dr. Dwi Susilaningsih bersama rekannya dari NITE
        Jepang, Dr. Sekiguchi.

        Meski banyak yang masih harus dibenahi untuk penyelenggaraan selanjutnya,
        secara umum saya kira pelaksanaan workshop tsb patut diacungi jempol.
        Setidaknya hal ini juga dirasakan teman-teman peserta workshop yg berjumlah
        sekitar 14 orang dr berbagai institusi di seluruh Indonesia...

        Banyak hal yg saya pelajari selama mengikuti workshop tsb, misal tentang
        Bioinformatics dan menggunakan data sekuensing utk menentukan spesies
        mikroalga...dst...dll...

        Saya kira itu dulu, silakan men-temen yg jadi peserta bisa sharing
        pengalamannya di sini. Oya Bu Dwi, foto bersamanya mungkin bisa diposting di
        sini kan? Gimana? Sekalian spy saya bisa unduh utk file pribadi saya.


        salam biotek,


        boy rahardjo sidharta
        faculty of biotechnology
        atma jaya yogyakarta university
        jl. babarsari 44
        yogyakarta-55281
        indonesia
        e-mail: <brsidharta@...> or
        <b_rasidh@...>
        http://brsidharta/wordpress.com
        http://brsidharta.edublogs.org

        founder: mailing list [Indonesia_HAB@yahoogroups.com],
        [kabiogama81@yahoogroups.com],
        [dyno_cyst_rg@yahoogroups.com]
        Yayasan Gema Mitra Bahari (GeMaRi) Yogyakarta
        ____________________________________________________________________________
        _____
        Dibuka pendaftaran Program Magister dan Double Degree Pascasarjana UAJY
        (MM - MTF atau sebaliknya; M.Hum - MTF; M.Hum - MM; MTS - MM dan MTArs
        (Digital)).
        Penerimaan mahasiswa setiap September dan Januari.
      • dwi susilaningsih
        Yth., Pak Boy dan teman-teman, Terimaksih atas ungkapan yang jujur apa-adanya, kami panitia mengaku banyak kekurangan dan mudah-mudahan akan memacu kami lebih
        Message 3 of 8 , Aug 15, 2008
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          Yth., Pak Boy dan teman-teman,

          Terimaksih atas ungkapan yang jujur apa-adanya, kami panitia mengaku banyak kekurangan dan mudah-mudahan akan memacu kami lebih baik lagi, maaf yang sebesar-besarnya.

          Untuk Foto dan milis sedang kami coba untuk mengkreasikan, pengenya bila kita membuka website phycology Indonesia, semua foto kita terpampang..
          Bila belum kesampaian CD-nya akan kita kirim..

          Kita masih punya primer nih, apakah masih ada yang berminat untuk belajar molekuler tekniknya?
          nanti kita bikin yang murah biar banyak yang bisa berpartisipasi? Bagaimanakah?

          Terimakasih semua,
          Salam,
          Dwi

          ----- Original Message ----
          From: brsidharta <brsidharta@...>
          To: indonesian_marine_biotechnology@yahoogroups.com
          Sent: Friday, 15 August 2008 1:45:08
          Subject: [indonesian_marine_biotechnology] Re: workshop microalgae di Cibinong

          Dear men-temen,

          Saya sangat senang bisa ikut workshop microalgae di Biotek LIPI, Cibinong yg
          diselenggarakan oleh Ibu Dr. Dwi Susilaningsih bersama rekannya dari NITE
          Jepang, Dr. Sekiguchi.

          Meski banyak yang masih harus dibenahi untuk penyelenggaraan selanjutnya,
          secara umum saya kira pelaksanaan workshop tsb patut diacungi jempol.
          Setidaknya hal ini juga dirasakan teman-teman peserta workshop yg berjumlah
          sekitar 14 orang dr berbagai institusi di seluruh Indonesia...

          Banyak hal yg saya pelajari selama mengikuti workshop tsb, misal tentang
          Bioinformatics dan menggunakan data sekuensing utk menentukan spesies
          mikroalga... dst...dll. ..

          Saya kira itu dulu, silakan men-temen yg jadi peserta bisa sharing
          pengalamannya di sini. Oya Bu Dwi, foto bersamanya mungkin bisa diposting di
          sini kan? Gimana? Sekalian spy saya bisa unduh utk file pribadi saya.

          salam biotek,

          boy rahardjo sidharta
          faculty of biotechnology
          atma jaya yogyakarta university
          jl. babarsari 44
          yogyakarta-55281
          indonesia
          e-mail: <brsidharta@mail. uajy.ac.id> or
          <b_rasidh@yahoo. com>
          http://brsidharta/ wordpress. com
          http://brsidharta. edublogs. org

          founder: mailing list [Indonesia_HAB@ yahoogroups. com],
          [kabiogama81@ yahoogroups. com],
          [dyno_cyst_rg@ yahoogroups. com]
          Yayasan Gema Mitra Bahari (GeMaRi) Yogyakarta
          ____________ _________ _________ _________ _________ _________ _
          _____
          Dibuka pendaftaran Program Magister dan Double Degree Pascasarjana UAJY
          (MM - MTF atau sebaliknya; M.Hum - MTF; M.Hum - MM; MTS - MM dan MTArs
          (Digital)).
          Penerimaan mahasiswa setiap September dan Januari.



          Get your preferred Email name!
          Now you can @... and @....
        • brsidharta
          The Bioinformatics session for this conference is supported by APBioNet. Pl. consider submitting a paper. Thank you, Shoba Ranganathan ... CALL FOR PAPERS ...
          Message 4 of 8 , Aug 20, 2008
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            The Bioinformatics session for this conference is supported by APBioNet.

            Pl. consider submitting a paper.

            Thank you,

            Shoba Ranganathan

            ----------------------------------------------------------------------------
            ---
            CALL FOR PAPERS
            ----------------------------------------------------------------------------
            ---
            IEEE/Innovations 2008
            5th International Conference on Innovations in Information Technology
            December 16-18, 2008
            Al Ain, United Arab Emirates

            ----------------------------------------------------------------------------
            ---
            Conference website: http://www.it-innovations.ae/
            ----------------------------------------------------------------------------
            ---

            BACKGROUND
            ----------------------------------------------------------------------------
            ---
            Innovations in Information Technology (Innovations'08), is a premier
            Forum for the presentation and discussion of technology advances and
            research results in the field of Information Technology (IT). Held for
            the first time in the oasis city of Al Ain, the fourth largest city in
            the United Arab Emirates (UAE), Innovations '08 is the fifth in the
            series that has been held in Dubai since 2004. The latest research
            advances in fields ranging from traditional computer science to
            evolving web technologies, bioinformatics and healthcare informatics
            are explored in Innovations' technical sessions.

            Innovations'08 is technically co-sponsored by IEEE Communication
            Society. Accepted papers will be published by IEEE and fully indexed
            in IEEEXplore.

            KEYNOTE SPEAKERS
            ----------------------------------------------------------------------------
            ---
            Mike S. Zafirovski, President and CEO, Nortel
            Dharma P. Agrawal, OBR Distinguished Professor of Computer Science

            SOCIAL PROGRAM
            ----------------------------------------------------------------------------
            ---
            - Dubai City Tour and Dhow Cruise
            - Desert Safari

            AUTHOR'S SCHEDULE (Deadlines):
            ----------------------------------------------------------------------------
            ---
            Paper and poster submissions due: September 1, 2008
            Notification of acceptance: October 3, 2008
            Final camera ready paper due: November 2, 2008

            TOPICS OF INTEREST
            ----------------------------------------------------------------------------
            ---
            Topics include, but are not limited to:

            - Communication networks and security
            - Information systems and services
            - Bioinformatics and healthcare informatics
            - Computing systems

            SPECIAL SESSIONS:
            ----------------------------------------------------------------------------
            ---
            - Realtime Visual Analysis and Visual Communication of In-Vivo and
            In-Silico Biology
            Organizer: Dr. Pablo de Heras Ciechomski, CEO Visualbiotech , Switzerland

            - Innovations in Arabic Language Technologies
            Organizer: Dr. Haikal El Abed, Braunschweig Technical University, Germany

            TUTORIALS:
            ----------------------------------------------------------------------------
            ---
            - Security Challenges in Wireless Mesh Networks
            By Dharma P. Agrawal, OBR Distinguished Professor of Computer Science

            - Introduction to WAN Planning and Design
            By Algirdas Pakstas, Professor, London Metropolitan University

            - Technology as a driver of innovation and catalyst for growth
            By Mark Walker, Microsoft Gulf region

            - Information Technology in the Financial Services Sector
            By Ayman Fathallah, Regional Director Middle East

            WORKSHOPS:
            ----------------------------------------------------------------------------
            ---
            - Robotics and Interactive Media
            - Cognitive Science

            CONTACT:
            ----------------------------------------------------------------------------
            ---
            Contact: Innovations08@...
            _______________________________________________
            Announce mailing list
            http://www.apbionet.org
            ____________________________________________________________________________
            _____
            Dibuka pendaftaran Program Magister dan Double Degree Pascasarjana UAJY
            (MM - MTF atau sebaliknya; M.Hum - MTF; M.Hum - MM; MTS - MM dan MTArs
            (Digital)).
            Penerimaan mahasiswa setiap September dan Januari.
          • brsidharta
            ****************************Announcement**************************** Open Access Articles from ISMB 2008 Did you miss the 16th Annual International Conference
            Message 5 of 8 , Aug 26, 2008
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              ****************************Announcement****************************

              Open Access Articles from ISMB 2008

              Did you miss the 16th Annual International Conference on Intelligent
              Systems for Molecular Biology (ISMB) in Toronto? You can view the
              conference proceedings online now! The editorials and many of the
              original papers are Open Access articles and can be viewed for free
              by the public.

              To access the ISMB 2008 conference proceedings visit:
              http://www.oxfordjournals.org/page/2909/5

              ****************************Announcement****************************
              Bioinformatics -- Table of Contents Alert

              A new issue of Bioinformatics
              has been made available:


              1 September 2008; Vol. 24, No. 17

              URL:
              http://bioinformatics.oxfordjournals.org/content/vol24/issue17/index.dtl?eto
              c




              ----------------------------------------------------------------
              REVIEW PAPER
              ----------------------------------------------------------------

              ---------------------------------------
              DATA AND TEXT MINING
              ---------------------------------------

              Hanchuan Peng
              Bioimage informatics: a new area of engineering biology
              Bioinformatics 2008 24: 1827-1836; doi:10.1093/bioinformatics/btn346.
              Open Access
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1827?et
              oc

              ----------------------------------------------------------------
              ORIGINAL PAPERS
              ----------------------------------------------------------------

              ---------------------------------------
              GENOME ANALYSIS
              ---------------------------------------

              Gyan P. Srivastava, Juyuan Guo, Huidong Shi, and Dong Xu
              PRIMEGENS-v2: genome-wide primer design for analyzing DNA methylation
              patterns of CpG islands
              Bioinformatics 2008 24: 1837-1842; doi:10.1093/bioinformatics/btn320.
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1837?et
              oc

              Jie Wu, Douglas H. Sieglaff, Joshua Gervin, and Xiaohui S. Xie
              Discovering regulatory motifs in the Plasmodium genome using comparative
              genomics
              Bioinformatics 2008 24: 1843-1849; doi:10.1093/bioinformatics/btn348.
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1843?et
              oc

              ---------------------------------------
              SEQUENCE ANALYSIS
              ---------------------------------------

              Jiajian Liu and Gary D. Stormo
              Context-dependent DNA recognition code for C2H2 zinc-finger transcription
              factors
              Bioinformatics 2008 24: 1850-1857; doi:10.1093/bioinformatics/btn331.
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1850?et
              oc

              James Lara, Robert M. Wohlhueter, Zoya Dimitrova, and Yury E. Khudyakov
              Artificial neural network for prediction of antigenic activity for a major
              conformational epitope in the hepatitis C virus NS3 protein
              Bioinformatics 2008 24: 1858-1864; doi:10.1093/bioinformatics/btn339.
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1858?et
              oc

              ---------------------------------------
              STRUCTURAL BIOINFORMATICS
              ---------------------------------------

              David W. Ritchie, Dima Kozakov, and Sandor Vajda
              Accelerating and focusing protein-protein docking correlations using
              multi-dimensional rotational FFT generating functions
              Bioinformatics 2008 24: 1865-1873; doi:10.1093/bioinformatics/btn334.
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1865?et
              oc

              ---------------------------------------
              GENE EXPRESSION
              ---------------------------------------

              Huai Li and Ming Zhan
              Unraveling transcriptional regulatory programs by integrative analysis of
              microarray and transcription factor binding data
              Bioinformatics 2008 24: 1874-1880; doi:10.1093/bioinformatics/btn332.
              Open Access
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1874?et
              oc

              Shuiwang Ji, Liang Sun, Rong Jin, Sudhir Kumar, and Jieping Ye
              Automated annotation of Drosophila gene expression patterns using a
              controlled vocabulary
              Bioinformatics 2008 24: 1881-1888; doi:10.1093/bioinformatics/btn347.
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1881?et
              oc

              Blaise Hanczar and Edward R. Dougherty
              Classification with reject option in gene expression data
              Bioinformatics 2008 24: 1889-1895; doi:10.1093/bioinformatics/btn349.
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1889?et
              oc

              ---------------------------------------
              GENETICS AND POPULATION ANALYSIS
              ---------------------------------------

              Nils Homer, Waibhav D. Tembe, Szabolcs Szelinger, Margot Redman, Dietrich
              A. Stephan, John V. Pearson, Stanley F. Nelson, and David Craig
              Multimarker analysis and imputation of multiple platform pooling-based
              genome-wide association studies
              Bioinformatics 2008 24: 1896-1902; doi:10.1093/bioinformatics/btn333.
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1896?et
              oc

              ---------------------------------------
              SYSTEMS BIOLOGY
              ---------------------------------------

              M.A. Marchisio and J. Stelling
              Computational design of synthetic gene circuits with composable parts
              Bioinformatics 2008 24: 1903-1910; doi:10.1093/bioinformatics/btn330.
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1903?et
              oc

              Heng Lian, William A. Thompson, Robert Thurman, John A.
              Stamatoyannopoulos, William Stafford Noble, and Charles E. Lawrence
              Automated mapping of large-scale chromatin structure in ENCODE
              Bioinformatics 2008 24: 1911-1916; doi:10.1093/bioinformatics/btn335.
              Open Access
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1911?et
              oc

              Abhishek Garg, Alessandro Di Cara, Ioannis Xenarios, Luis Mendoza, and
              Giovanni De Micheli
              Synchronous versus asynchronous modeling of gene regulatory networks
              Bioinformatics 2008 24: 1917-1925; doi:10.1093/bioinformatics/btn336.
              Open Access
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1917?et
              oc

              Yung-Keun Kwon and Kwang-Hyun Cho
              Coherent coupling of feedback loops: a design principle of cell signaling
              networks
              Bioinformatics 2008 24: 1926-1932; doi:10.1093/bioinformatics/btn337.
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1926?et
              oc

              Vladislav Vyshemirsky and Mark Girolami
              BioBayes: A software package for Bayesian inference in systems biology
              Bioinformatics 2008 24: 1933-1934; doi:10.1093/bioinformatics/btn338.
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1933?et
              oc

              ---------------------------------------
              DATA AND TEXT MINING
              ---------------------------------------

              T. Theodosiou, N. Darzentas, L. Angelis, and C. A. Ouzounis
              PuReD-MCL: a graph-based PubMed document clustering methodology
              Bioinformatics 2008 24: 1935-1941; doi:10.1093/bioinformatics/btn318.
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1935?et
              oc

              Han Zhang, Hsin-Chou Yang, and Yaning Yang
              PoooL: an efficient method for estimating haplotype frequencies from large
              DNA pools
              Bioinformatics 2008 24: 1942-1948; doi:10.1093/bioinformatics/btn324.
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1942?et
              oc

              ----------------------------------------------------------------
              APPLICATIONS NOTE
              ----------------------------------------------------------------

              ---------------------------------------
              SEQUENCE ANALYSIS
              ---------------------------------------

              Art F. Y. Poon, Fraser I. Lewis, Simon D. W. Frost, and Sergei L.
              Kosakovsky Pond
              Spidermonkey: rapid detection of co-evolving sites using Bayesian
              graphical models
              Bioinformatics 2008 24: 1949-1950; doi:10.1093/bioinformatics/btn313.
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1949?et
              oc

              ---------------------------------------
              STRUCTURAL BIOINFORMATICS
              ---------------------------------------

              Shantanu Sharma, Feng Ding, and Nikolay V. Dokholyan
              iFoldRNA: three-dimensional RNA structure prediction and folding
              Bioinformatics 2008 24: 1951-1952; doi:10.1093/bioinformatics/btn328.
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1951?et
              oc

              Paolo Marcatili, Alessandra Rosi, and Anna Tramontano
              PIGS: automatic prediction of antibody structures
              Bioinformatics 2008 24: 1953-1954; doi:10.1093/bioinformatics/btn341.
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1953?et
              oc

              Martin Prokop, Jan Adam, Zdenek Kriz, Michaela Wimmerova, and Jaroslav
              Koca
              TRITON: a graphical tool for ligand-binding protein engineering
              Bioinformatics 2008 24: 1955-1956; doi:10.1093/bioinformatics/btn344.
              Open Access
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1955?et
              oc

              ---------------------------------------
              GENE EXPRESSION
              ---------------------------------------

              Tae-Min Kim, Seon-Hee Yim, Yong-Bok Jeong, Yu-Chae Jung, and Yeun-Jun
              Chung
              PathCluster: a framework for gene set-based hierarchical clustering
              Bioinformatics 2008 24: 1957-1958; doi:10.1093/bioinformatics/btn357.
              Open Access
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1957?et
              oc

              Eoghan D. Harrington and Peer Bork
              Sircah: a tool for the detection and visualization of alternative
              transcripts
              Bioinformatics 2008 24: 1959-1960; doi:10.1093/bioinformatics/btn361.
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1959?et
              oc

              ---------------------------------------
              GENETICS AND POPULATION ANALYSIS
              ---------------------------------------

              Dominik Heider, Daniel Kessler, and Angelika Barnekow
              Watermarking sexually reproducing diploid organisms
              Bioinformatics 2008 24: 1961-1962; doi:10.1093/bioinformatics/btn342.
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1961?et
              oc

              ---------------------------------------
              SYSTEMS BIOLOGY
              ---------------------------------------

              Frank T. Bergmann and Herbert M. Sauro
              Comparing simulation results of SBML capable simulators
              Bioinformatics 2008 24: 1963-1965; doi:10.1093/bioinformatics/btn319.
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1963?et
              oc

              Garrett M. Dancik and Karin S. Dorman
              mlegp: statistical analysis for computer models of biological systems
              using R
              Bioinformatics 2008 24: 1966-1967; doi:10.1093/bioinformatics/btn329.
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1966?et
              oc

              ---------------------------------------
              DATA AND TEXT MINING
              ---------------------------------------

              Songhua Xu, James McCusker, and Michael Krauthammer
              Yale Image Finder (YIF): a new search engine for retrieving biomedical
              images
              Bioinformatics 2008 24: 1968-1970; doi:10.1093/bioinformatics/btn340.
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1968?et
              oc

              ---------------------------------------
              DATABASES AND ONTOLOGIES
              ---------------------------------------

              Jung-Wei Fan and Carol Friedman
              Semantic reclassification of the UMLS concepts
              Bioinformatics 2008 24: 1971-1973; doi:10.1093/bioinformatics/btn343.
              Open Access
              http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/17/1971?et
              oc

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              _______________________________________________________________________
              Copyright (c) 2008 by the Oxford University Press.
              ____________________________________________________________________________
              _____
              Dibuka pendaftaran Program Magister dan Double Degree Pascasarjana UAJY
              (MM - MTF atau sebaliknya; M.Hum - MTF; M.Hum - MM; MTS - MM dan MTArs
              (Digital)).
              Penerimaan mahasiswa setiap September dan Januari.
            • yogiara
              Dear sir/madam,   We would like to inform you that School of Biotechnology Atma Jaya Catholic University of Indonesia, in cooperation with American Society
              Message 6 of 8 , Aug 27, 2008
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                Dear sir/madam,

                We would like to inform you that School of Biotechnology Atma Jaya Catholic University of Indonesia, in cooperation with American Society for Microbiology (ASM) will hold “International Microbial Biotechnology Conference and Workshop on Metagenome: Microbes for a beautiful and prosperous world” on November 11th-13th,2008. For detail information, please visit our website http://www.imbc-indonesia.com or the attached brochure (2nd Announcement).

                 

                We would really appreciate it if you can help us disseminate this information to your colleagues. Thank you.


                 

                Important Date

                Deadline Early bird registration fee: 8 September 2008 (Special Price).

                 

                Best regards,


                IMBC COMMITTEE
                Jakarta, Indonesia

                 

                >
              • brsidharta
                Penelitian Riset Halofosfor Memenangi Penghargaan L Oreal Selasa, 2 September 2008 | 01:09 WIB Jakarta, Kompas - Setiap tahun Indonesia membutuhkan semakin
                Message 7 of 8 , Sep 2, 2008
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                  Penelitian
                  Riset Halofosfor Memenangi Penghargaan L'Oreal
                  Selasa, 2 September 2008 | 01:09 WIB

                  Jakarta, Kompas - Setiap tahun Indonesia membutuhkan semakin banyak
                  halofosfor, jenis fosfor yang banyak digunakan di industri, khususnya
                  industri lampu fluorescent (lampu hemat energi). Di sisi lain, bahan baku
                  fosfor masih banyak yang didatangkan dari luar negeri.

                  Inilah yang kemudian mendasari riset Camellia Panatarani (34), doktor ilmu
                  teknik lulusan Universitas Hiroshima, Jepang, yang kini bekerja di Jurusan
                  Fisika Fakultas Matematika dan Ilmu Pengetahuan Alam (MIPA) Universitas
                  Padjadjaran, Bandung. Melalui risetnya, Camellia berusaha membuat halofosfor
                  dengan metode larutan sederhana guna membantu industri lampu hemat energi.

                  Riset tersebut pekan lalu ia pertahankan di depan juri Penghargaan L’Oreal
                  Indonesia Fellowships for Women in Science 2008. Camellia akhirnya menjadi
                  salah satu dari tiga ilmuwan muda yang meraih penghargaan L’Oreal yang
                  diselenggarakan dengan dukungan Komisi Nasional Indonesia untuk UNESCO
                  (Badan PBB untuk Pendidikan, Ilmu Pengetahuan, dan Kebudayaan).

                  Kedua pemenang lainnya adalah Asmi Citra Malina, peneliti dari Fakultas Ilmu
                  Kelautan dan Perikanan Universitas Hasanuddin, Makassar, dan Atik Retnowati
                  dari Fakultas MIPA Universitas Indonesia. Asmi meneliti penggunaan DNA
                  sintetik dalam meningkatkan sistem kekebalan tubuh ikan kerapu macan,
                  sementara Atik meneliti taksonomi genus marasmielus (jamur) di Jawa dan Bali
                  berdasarkan data morfologi dan molekuler.

                  Penghargaan diberikan pada Kamis (28/8) malam di Jakarta. Melalui program
                  yang sudah diselenggarakan untuk kelima kalinya ini, ketiga peneliti dapat
                  memberikan kontribusi bagi kemajuan di bidang ilmu-ilmu material dan
                  kehidupan di Indonesia.

                  Program For Women in Science didirikan tahun 1998 (diperbarui tahun 2004)
                  oleh L’Oreal dan UNESCO untuk mengakui, menyemangati, dan mendukung
                  perempuan di bidang sains di seluruh dunia. Pemenang penghargaan ini
                  selanjutnya menjadi bagian komunitas unik For Women in Science bernama
                  AGORA. Melalui komunitas ini, mereka dapat bekerja sama guna mendukung
                  perempuan di bidang sains pada masa datang.

                  Dari 500 perempuan dari 50 lebih negara yang telah diakui prestasinya
                  melalui program ini, sebanyak 11 di antaranya berasal dari Indonesia.
                  (*/NIN)
                  ____________________________________________________________________________
                  _____
                  Dibuka pendaftaran Program Magister dan Double Degree Pascasarjana UAJY
                  (MM - MTF atau sebaliknya; M.Hum - MTF; M.Hum - MM; MTS - MM dan MTArs
                  (Digital)).
                  Penerimaan mahasiswa setiap September dan Januari.
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