I've never heard of it until now. I did a quick search. There isn't much out
there and the two references below are for dogs. I couldn't find anything on
pubmed and I can't access vet journals. There were references to not using
it in dogs with diabetes and one said it should only be used in dogs with
well controlled diabetes. I'm going to ask the cardiologist at our next
visit in 2 weeks. The Vetmedin prescribing information notes "abnormal serum
electrolyte, protein, and glucose values" but doesn't say if glucose values
are high or low.
"Pimobendan augments exocytotic release of insulin secretory granules from
pancreatic islet cells in a dose-dependent manner by directly sensitizing
the intracellular Ca++-sensitive exocytotic mechanism. It has been suggested
by some that this mechanism could lead to an increase in diabetes in
patients chronically treated with pimobendan. There have been reports of
diabetes developing in a few patients enrolled in pimobendan treatment
studies. However, the significance of that occurrence is not clear."
See Important Safety Information near the bottom of the page.
Behalf Of Mary M
Sent: Wednesday, June 26, 2013 8:34 PM
Subject: [FH] Vetmedin....Diabetes?
Has anyone heard of Vetmedin causing Diabetes in a cat? My Smudge with a
deformed heart now has Diabetes and someone told me that Vetmedin can cause
it. Is that true?
Mary & Smudge & Alice
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