Re: [FH] Re: cyproheptadine
- Susan wrote:
> --- JettawayFCRs@... wrote:Here is a referrence to the interaction between Cyproheptadine and calcium
> > > He was taking cyproheptadine to stimulate his appetite, but I
> understand that it can cause a possibly fatal reaction causing the BP to
> drop too low, so I have been afraid to give it to him...so far, I'm getting
> him to eat some without it.
> > This is interesting. I lost a kitty in Dec. just a couple of days after
> starting him on cyproheptadine. He went downhill
> > very fast
channnel blockers. It is from Dr. Plumb's Book of Pills. Our Internal
Medicine specialist had seen this interaction several times before in the ER,
and she was very upset that our heart kitty was given Cypro. Lucie never
recovered and died 2 weeks later.
Personally, I would not tempt fate, knowing this.
"Like other H1 receptor antihistamines, cypro acts by competing with
histamine for sites on H1 -receptor sites on effector cells. Antihistamines
do not block histamine release, but can antagonize its effects. Cyrpo also
possesses potent antiserotonin activity and reportedly has calcium channel
blocking action as well."
This has the effect of a drop in blood pressure.
Anyes and the girls
- Many people have mentioned slippery elm bark on this website as an
appetite stimulant that is safe for cats with heart issues to take.
Since my cat isn't eating much because zenequin has caused him to feel
ill I called the vet's office yesterday to see what the vet thought of
slippery elm bark. A doctor that is brand new to the practice called
me back today and said I should give my cat two pills of
cyproheptadine a day. Based on everything that I have read at this
website, I know that 2 pills will be much too large. However, I am
also concerned about using cypro because in 2006 people were posting
about they had heard that animals with heart disease, high blood
pressure, and an overactive thyroid should not take this medicine.
Since my cat is on tapazol, norvasc, and enacard, I am wondering if
people still have concerns about using cypro?
- Hi Melissa,
In a message dated 12/25/07 2:45:46 PM, gillinov@... writes:
> Many people have mentioned slippery elm bark on this website as anI can't speak for anyone else...but I mention slippery elm bark as a remedy
> appetite stimulant that is safe for cats with heart issues to take.
for nausea, dig. tract irritation, and elimination problems (both constipation
and diarrhea). It *may* stimulate appetite to the extent that it relieves
problems such as nausea etc, which can adversely affect appetite. But slippery elm
is not an appetite stimulant per se.
> Since my cat isn't eating much because zenequin has caused him to feelMost conventional veterinarians have no training or experience with
> ill I called the vet's office yesterday to see what the vet thought of
> slippery elm bark.
> A doctor that is brand new to the practice calledCyproheptadine is a synthetic anti-histamine that has a secondary effect of
> me back today and said I should give my cat two pills of
> cyproheptadine a day.
stimulating appetite in cats.
It is not low risk. From
http://www.petplace.com/drug-library/cyproheptadine-periactin/page1.aspx : "Cyproheptadine should be used with caution in animals
with glaucoma, prostate gland enlargement, heart failure or gastrointestinal
From http://www.marvistavet.com/html/cyproheptadine.html :
"Drowsiness is a common side effect. Occasionally a cat will have a what is
called a “paradoxic” reaction and become excited. As with other
antihistamines, “anticholinergic effects” occur at higher doses or overdose. These effects
include: Urine retention, increased pressure in the eye (only of concern in
patients predisposed to glaucoma), dry mouth, increased heart rate, elevated
body temperature....Cyproheptadine is best avoided in patients with glaucoma,
recovering from urinary blockage, and heart failure patients."
> Based on everything that I have read at thisTypical dose for cats for appetite stimulation is 1-4 mg 1-2x/day. Each pill
> website, I know that 2 pills will be much too large.
> However, I amYes, see above.
> also concerned about using cypro because in 2006 people were posting
> about they had heard that animals with heart disease, high blood
> pressure, and an overactive thyroid should not take this medicine.
> Since my cat is on tapazol, norvasc, and enacard, I am wondering ifI (my opinion only) have concerns about using cyproheptadine with any cat.
> people still have concerns about using cypro?
Just from an ethical standpoint alone, I think it's problematic to give a drug
that takes away control over appetite when a cat has "legitimate" reason not to
eat. I think a safe, sound solution is to reduce or remove the issues that
are negatively affecting appetite and support the digestive system, while also
using techniques such as spoon feeding, tasty bribes, and small, frequent meals
of a bland food that encourage the cat to eat. In your case, you believe that
an antibx is causing the inappetance. This is not uncommon. So some steps to
pursue would be to reduce the amt of antibx needed by using other means to
help manage the infection and soothe the dig. tract with slippery elm bark.
A low-risk, gentle appetite stimulant is injectable Vit B12, which a vet can
provide as prefilled syringes. // Rosemary
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- Hi, Melissa,
I can't answer your question as to how cypro will
interact with the other meds your cat is on - but I
can tell you that using cypro has helped my kitty Zora
to go on eating. She has many reasons to feel
nauseated and not all of them can be addressed beyond
what I am already doing -
Zora is hyperT, CRF, HCM and pancreatitis. The
tapazole she takes for her hyperT can cause nausea and
inappetance, but without it her thyroid would be out
of control. She gets everything she needs for her
kidney disease (fluids, phos binders, etc) but her
numbers are high and CRF can cause nausea and
inappetance. She is on antibiotics for a UTI and they
too cause the same. When we took her off the
antibiotics too early because we thought her UTI was
cured, she had a major kidney crash and we almost lost
her. She is back on antibiotics.
My point? It's definitely best to try to figure out
what underlies the inappetance and address that. But
you can't always get rid of all of the causes of
nausea and inappetance. When that is the case,
sometimes you have to use "artificial means" as long
as they do no harm. For us, cyproheptadine has been a
miracle drug. It keeps Zora eating. As I'm sure you
know, unlike humans, cats can't fast. THey must
We started with a very low dose of cypro, much lower
than you're cat was prescribed - 1/8 of 4mg tab twice
a day. After Zora's kidney crash, we increased it to
1/4 of the tab twice a day. We have been lucky she
has had no side effects from it. You do need to watch
for hyperactive reactions and lethargy reactions.
Zora also takes atenelol for her heart disease and
there hasn't been an interaction problem with that.
I do use slippery elm bark, but I use that more for
digestive issues - diarrhea and constipation.
Hope this helps.