Re: Petuly's new blood work doesn't look too good!
- hi Thelma,
First thing that I would change and see if it makes any difference
with her kidney and liver values is stop the Miralax. I used to
give it to Chris last summer, but then found out it's very damaging
to the kidneys and liver. All the warnings say that it's
contraindicated in patients with kidney and liver disease. I can't
find any information on why though, only that it's not supposed to
be used if you have kidney/liver issues.
I would try another type of laxative. Senna (herb) is good, we used
to use that on our angel Ducky. You might also try Benefiber. It
used to be made from guar gum, but they changed it to wheat fiber,
which I know isn't great either, but the lesser of two evils, ya
know! We give Benefiber to our Puddy, because he has rectal
prolapse, and any constipation makes him prolapse, so we have to
keep things moving for him.
Phosphorus binders can inhibit the absorption of some medications,
so it's best to give the meds an hour apart from the binders. You'd
give the binders with food, say the main meals, so give the binders
with the main meals and the meds with a tiny bit of food (so not to
upset the tummy) w/o the binders at least an hour away from the food
with the binders in it. Since Petruly has high calcium levels, a
calcium based binder wouldn't be appropriate for her. I'd go with
something like the aluminum hydroxide instead.
Denamarin is a combination of s-adenosyl methionine (SAMe) and milk
thistle extract, and from what I've read, it's safe for CRF kitties.
I used to give SAMe it to my angels Fritzy and Sweetie. The only
thing about it is that it should be given on an empty stomach,
and "sometimes" it can cause tummy upset. In all the literature
about Denamarin that I found today it says there are no side
effects, but I know from experience when giving SAMe to my guys in
the past, that it did cause upset tummy in Fritzy. Here's some info
from the manufacturer that I found.
or if the long links don't work:
>>Cholesterol*: 167, 293 (77 - 258) - Is this because of the organ
>>No...high cholesterol in cats can be an after effect from the kidney
"Cholesterol is a form of fat. Cholesterol can be increased in the
bloodstream for many reasons in dogs. It is much less common for
cats to have increased cholesterol. Some of the diseases that cause
elevated cholesterol are hypothyroidism, Cushing's disease, diabetes
and kidney diseases that cause protein to be lost in the urine. High
cholesterol does not predispose dogs and cats to heart and blood
vessel disease as it does in people."
>>Amylase: 1286, 1454 (496 - 1874) - Does this mean pancreatitis?
>>Elevated Amylase can be a sign of pancreatitis in dogs, but not
always, and usually not in cats. More typically it's common in cats
with kidney disease.
"Also, these enzymes are excreted by the kidney, and the presence of
concurrent kidney disease (which is fairly common in cats) can
falsely elevate the serum amylase and lipase levels."
>>BUN*: 44, 46 (15 - 32)
Creatinine*: 2.4, 3.0 (0.9 - 2.1)
Phosphorus*: 4.5, 5.8 (3.0 - 6.3)
Calcium*: 10.2, 11.8 (8.9 - 11.5)
Potassium: 5.1, 4.4 (3.6 - 5.4)
Alk. phos.*: 66, 99 (10 - 72)
ALT*: 311, 656 (29 - 145)
AST*: 105, 211 (12 - 42)
>>Though her BUN and Creatinine are a little high, they're not
horrible. Her Phos is just slightly above what folks would like it
to be before starting phos binders. On the CRF groups I'm on, they
say anything above 5.0 then start binders, but 5.8 isn't that bad.
You could probaby get away with minimal use of the phos binders to
bring that down a little.
Hopefully on the Denamarin, those liver values will come down.
Another supplement that is very helpful in treating liver disease is
artichoke extract. It helps with the elimination of the toxins from
detoxing the liver.
>>Comment on 4/3/08: Sample slightly hemolyzed (this sounds bad! What
can it be?)
Hematocrit: 30, 29 (31 - 46)
>>Hemolyzed blood can be caused from improper taking and prep of the
sample, or it can have something to do with anemia. Since Petruly is
a little anemic, I'd keep an eye on that. Doing B12 shots could
help, and possibly if it gets too low, Epogen injections to bring
the hematocrit back up.
f or http://tinyurl.com/69xtz2 for info about hemolyzed blood.
>>About the thyroid the doctor said that in the case of a CRF kitty
they prefer not to treat the thyroid as it may actually help the
>>You know...I've been told this too, and we left Snowball's hyperT
untreated for almost a year, and it was bad for her. Since we
started her on the thyroid med (Tapazole/methimazole), her kidney
values haven't gotten worse, and her thyroid is now normal...for now
anyway. Having hyperthyroid is very bad for the heart and every
other organ. I would maybe try to treat the thyroid very
cautiously, using very small doses of the med and see how Petruly
does. You can always stop it if it makes things worse. We give
Snowball the transdermal cream, because the medication usually
causes nausea and vomiting in cats, and with Snowball's spewing
problems, we didn't even want to go there. We use just a tiny dose
on her and it's so far helping. It's been about 5 weeks on it now,
and we did bloodwork on her after 3 weeks on it and her kidney
values were not any worse on the thyroid meds.
I hope some of this helps, and that some of the other folks can
chime in with more info for you.
Hang in there.
Carol and Snowball and the gang