spiro plus lasix, not in place of lasix
>I have had several peopleJust wanted to point out that generally speaking,
>from the support groups
>on here suggest using
>spironolactone instead of
>Lasix but the cardiologist
>and my vet (who will only
>do what cardiologist says)
>will not prescribe it.
lasix is used until it cannot keep up with fluid
build-up. At this point additional drugs
might be added, for example spironolactone.
My cat's cardiologist preferred HCTZ as a
secondary diuretic for my cat's particular case,
but eventually after much insisting on my
part, finally called in a script for spiro.
Spironolactone is only a weak diuretic and its
primary help in heart disease may be through
effects other than the diuretic effect most
likely through inhibiting the Renin-Angiotensin-
adosterone pathway that the ACE-inhibitor also
(See the Human RALES study for more info).
The reference to the primary research
article and a summary are included
Although the RALES study noted that
hyperkalemia was not an issue, a follow
up study indicated that when potassium
levels were not monitored, there was an
increase in hyperkalemia associated
illness and death. It is important to keep track of
serum potassium levels when taking both drugs.
(See follow up to Human RALES study)
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