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[FH] Fwd: Re: Tazo - blood clot - VERY IMPORTANT

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  • lorkatz2004
    ... Aspirin Aspirin is a medication that most people have in their bathroom cabinets as a matter of routine. We see Aspirin advertised daily on the television.
    Message 1 of 4 , Apr 30, 2007


      Aspirin is a medication that most people have in their bathroom
      cabinets as a matter of routine. We see Aspirin advertised daily on
      the television. We self-medicate with Aspirin without thinking twice
      about it.

      It is understandable that cat owners often assume it is safe to give
      their kitties aspirin. While Aspirin can be a useful medication for a
      cat, over-dosing is not only harmful, it can be lethal!
      Aspirin, acetylsalicylic acid (ASA) or Acetaminophen ...
      They are the same basic medication.
      One extra strength Acetaminophen tablet can kill a small cat

      Aspirin Is A Useful Medication For Cats

      Aspirin is used in cats in the treatment of cardiomyopathy,
      arthritis, pain, and fever. The dose is based on the cat's weight and
      the condition being treated, and is determined by the veterinarian.
      Some conditions, such as hypoalbuminemia, will require a reduction in

      In fact aspirin is a very effective pain reliever for cats, if
      nothing else can be obtained, or is available. ASA, the chemical name
      for aspirin, is sometimes administered to animals to relieve minor
      pain and discomfort.For arthritis, we do sometimes use aspirin but it
      must be used cautiously and it is important to know the patient's
      medical condition well prior to its use. As in humans with heart
      risks, a cat with HCM may be prescribed Aspirin. 1/4 of a baby aspirin
      will help with pain and swelling for about 92/96 hours in a cat.
      Cats with HCM are often advised to get baby aspirin twice weekly
      or once every 5 days to prevent the forming of blood clots, which can
      kill them.

      The Danger

      Acetaminophen is toxic to cats, aspirin is extraordinarily easy to
      overdose in cats because the half-life of aspirin in a cat is 72 hours
      (3 days!) If you know what you're doing, you can give aspirin to your
      cat. But cats have different metabolisms to humans, and break aspirin
      down only very slowly. Basically they lack an enzyme that breaks down
      the salicylic acid in the liver, so the drug stays active in their
      systems for much longer than people or dogs.

      So while you can give aspirin to a human at doses of 10mg/kg of
      body weight every 6 hours, with a cat, you can give the same dose (10
      mg/kg) - but every 48 hours, not 6 hours. That's the timing for
      anti-platelet activity. Aspirin interferes with platelets, which are
      responsible for helping the blood to clot. Disruption of platelet
      function increases the amount of time it takes the blood to clot after
      being cut.

      Aspirin in high doses in a cat can lead to hepatitis, gastric
      irritation, and respiratory problems.
      Aspirin toxicity most often is a result of a cat accidentally
      eating an aspirin... or if it is given a human dose .

      Toxicity can also occur with repeated aspirin administration. .

      NEVER give cats acetaminophen (Tylenol), as it will kill them very quickly

      Correct Dosing of Aspirin

      Aspirin can be used in very specific doses for cats.


      A dose of 10mg/kg

      Every 48-72 hrs

      NOTE: There are published studies indicating that aspirin is safe
      when dosed from 10 to 25mg/kg every 48 to 72 hours and one study
      indicating no problems when it was dosed at 162mg/cat once a week.
      Only use these higher dosing recommendations if your cat is under
      veterinary care.

      Never give your cat aspirin more often then every second day

      Aspirin Poisoning

      ASA toxicity is the poisoning of the animal due to overdose or to
      long-term use. Aspirin toxicity (salicylate toxicity) is poisoning
      that occurs following the ingestion of aspirin or aspirin-containing
      products. Aspirin toxicity usually occurs because of the ingestion of
      improperly stored drugs or the administration of the incorrect dose of

      Cats are more susceptible to the effects of aspirin than are dogs
      because they are unable to metabolize the drug as quickly. Young
      animals are more susceptible to the toxic effects than are adult animals.
      Giving cats aspirin can be very dangerous if it is not given
      correctly and under veterinary supervision. This is especially true
      for older cats.

      Symptoms of Aspirin Poisoning

      Common symptoms of aspirin toxicity in the cat may include:

      * lethargy
      * depression
      * high body temperature
      * muscle weakness
      * uncoordinated
      * unsteady when standing or walking
      * panting
      * decreased respiration
      * restlessness
      * anxiety
      * loss of appetite
      * abdominal pain
      * nausea
      * vomiting with or without blood
      * diarrhea
      * loss of appetite
      * extreme thirst
      * dilute urine
      * black stools
      * spontaneous bleeding may also occur causing pinpoint bruises to
      appear in the skin and on the gums (petechiae)
      * (rarely) seizures

      The symptoms of acute kidney failure are almost identical to
      the gastrointestinal symptoms of aspirin toxicity

      Diagnosis of Aspirin Poisoning

      Aspirin toxicity is diagnosed by a thorough history and physical
      examination and by laboratory tests. Any history of pain (or other)
      medication ingestion, especially within 5 days of the development of
      signs, is important information for the veterinarian. Complete blood
      counts (CBCs) will reveal blood abnormalities such as anemia (low red
      blood cell count), and blood chemistries will often show changes
      reflecting fluid and electrolyte imbalance. Other lab tests may be
      done. For example, salicylic acid, a component of aspirin, may be
      found in the blood. The easiest way of diagnosis aspirin poisoning is
      if your cat has a history of being given aspirin or if the cat
      accidentally ate some aspirin.

      Tests to confirm aspirin poisoning may include:

      * A complete blood count (CBC) is used to assess the cat's white
      blood cell count and red blood cell count. If the cat has intestinal
      bleeding secondary to ulceration of the stomach, the red blood cell
      count may be decreased. A biochemistry profile is a blood test used to
      assess internal organs such as the kidneys. Elevations in the kidney
      values indicate that the kidneys have been damaged. This blood test
      also indicates evaluation of the liver values, which is important
      because diseases of the liver could produce symptoms similar to those
      of aspirin toxicity.
      * A urinalysis is performed to assess the kidney's ability to
      concentrate urine. In cases of kidney damage, the urine becomes more
      dilute and appears lighter in color.
      * A blood gas is done to assess the pH of the blood. Animals that
      have aspirin toxicity often have a low blood pH (acidosis).
      * An activated clotting time (ACT) is a blood test done to measure
      a cat's ability to form a clot and to stop bleeding when cut. Because
      aspirin may interfere with the ability to form a lot, clotting tests
      such as the ACT may be prolonged.


      If you suspect your cat may have eaten aspirin, contact your
      veterinarian immediately. A specific antidote to counteract the
      effects of aspirin is not available. Cats are treated using the
      general principles of supportive care for poisoning. The initial goal
      is to maintain kidney function and fluid-electrolyte balance.
      Hospitalization is often required for two to five days. treatment may

      * Induction of vomiting
      * gastric lavage (pumping the stomach) to remove undigested pills
      if the cat is examined within four hours of ingestion.
      * Administration of activated charcoal to prevent absorption of
      aspirin from the stomach.
      * Placement of an intravenous (IV) catheter to administer IV
      fluids to re-hydrate and to treat or prevent kidney failure.
      * Administration of antacids such as misoprostol (Cytotec®),
      cimetidine (Tagamet®), famotidine (Pepcid AC®), or sucralfate
      (Carafate®) to prevent or treat ulceration of the stomach.
      * Administration of antiemetic (anti-vomiting) drugs such as
      metoclopramide (Reglan®), prochlorperazine (Compazine®) or
      chlorpromazine (Thorazine®).

      Without treatment, A cat with aspirin poisoning
      may go into a coma and death may occur

      Home Care

      If accidental ingestion has occurred, remove any remaining pills
      from the environment. Take your cat to a veterinarian as soon as
      possible for treatment. If you live more than 30 minutes from the
      veterinary hospital, call ahead for advice on whether or not to induce
      vomiting at home prior to transportation.
      If you have been administering aspirin and you note lethargy,
      depression, vomiting, black colored stools, pale gums, or loss of
      stop giving the aspirin and contact your veterinarian immediately.


      The outcome depends on the amount of aspirin ingested and the
      rapidity of treatment. If the toxicity has progressed to toxic
      hepatitis (inflammation of the liver), severe blood abnormalities, or
      coma, the prognosis is usually poor.

      Factors Limiting The Use of Aspirin In Cats

      Aspirin can be used in cats, but they must be healthy and a
      veterinarian needs to determine if there are any other medical
      problems in a cat patient before aspirin is administered. This
      determination is made based on the findings of a physical examination
      and blood tests. Of particular concern is the functional status of the
      liver, kidneys and thyroid gland. Aspirin should be used cautiously in
      cats with functional deficiencies of these organs. Since aspirin can
      irritate the stomach and affect platelet function, cats with bleeding
      gastrointestinal ulcers and bleeding disorders should not be given it.
      Some cats may be allergic to aspirin; its use is precluded in these
      cats as well.

      Veterinarians will need to see cat patients on aspirin
      frequently to monitor for toxicity

      Preventing Aspirin Poisoning

      * Never give your cat aspirin unless instructed to do so by a
      * Keep bottles of aspirin out of your pet's reach
      * Small packets of aspirin kept in pockets or purses are a danger
      to your cat.
      * If you spill the aspirin bottle, exercise special care in
      collecting all the pills.

      Giving Aspirin Under Veterinary Care

      If your cat's regular care involves administration of aspirin,
      give enteric-coated aspirin. Administer aspirin with food to limit
      stomach upset and never exceed the dose prescribed by your veterinarian.
      Regarding Aspirin & Your Cat...
      More is not necessarily better!

      Conditions That Mimic Aspirin Toxicity

      * Other diseases can have symptoms that appear similar to aspirin
      toxicity. These include:
      * Non-steroidal anti-inflammatory medications such as Rimadyl®,
      Etogesic®, phenylbutazone, flurbiprofen, and ibuprofen may cause
      identical symptoms as those caused by aspirin toxicity.
      * Administration of steroids can cause vomiting and stomach
      ulceration as well as increased thirst, urinations and urine dilution.
      These symptoms can mimic those of acute kidney failure.
      * Gastroenteritis (inflammation of the stomach and intestines) of
      any cause can mimic the gastrointestinal symptoms of aspirin toxicity.
      History of aspirin administration or intoxication is the best way to
      distinguish aspirin toxicity from other causes of gastroenteritis.
      * Pancreatitis (inflammation of the pancreas) can cause all of the
      symptoms associated with aspirin toxicity. Pancreatitis can be
      difficult to diagnose in the cat. Ethylene glycol (antifreeze)
      poisoning can cause symptoms similar to those of aspirin toxicity. A
      specific test can be performed to diagnose ethylene glycol poisoning
      if this is suspected.

      In feline-heart@yahoogroups.com, Leah Ferron <leahandhercats@...> wrote:
      > I am sorry I forgot your name,
      > Please, please, please be careful with this dosage of baby
      aspirin! 1 baby aspirin a day for a kitty is a LOT! My 6 foot, 275 lb.
      husband takes one baby aspirin a day. An 8-9 lb. kitty should not be
      getting that much aspirin. Seymour could easily be poisoned with this
      much aspirin! They can not process the aspirin that fast.
      > Leah and her cats and Angel Alec
      > binquist <binquist@...> wrote:
      > Re: baby aspirin
      > Hi, Diane. Earlier this week, an internal medicine vet specialist
      > recommended that i give Seymour 1 baby aspirin per day. the
      > recommended method is: disolve in small amount of water and use a
      > syringe to make sure he swallows the mixture.
      > Before, he was on 1 baby aspirin 2x week.
      > Seymour weighs 8.8lbs at this time.
      > Good luck with your kitties.
      > ---------------------------------
      > Ahhh...imagining that irresistible "new car" smell?
      > Check outnew cars at Yahoo! Autos.
      > [Non-text portions of this message have been removed]
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