47547RE: [FH] Zeke starting Furosemide
- Mar 21, 2013Janette,
I'm glad you asked that question. There is so much I still have to learn
about my cat's heart failure.
What I've read relating to human use of this drug is that combined the two
can contribute to lowering blood pressure more than benazepril alone. My cat
has been on both for about 8 weeks. Her blood pressure has been staying
around 80, which is considered normal, though a little low for my comfort. I
get her BP checked every 6-8 weeks or so when I get repeat blood work done.
This I found on the Marvista site and relates specifically to cats
"Benazepril is commonly used in combination with diuretics, especially
furosemide <http://www.marvistavet.com/html/body_furosemide.html> . In this
situation, monitoring kidney parameters is especially important as both
these medications serve to decrease blood supply to the kidney as they
support the heart. Should a heart failure crisis occur while a patient is on
these two medications, it will become necessary to rely on the diuretic to
resolve the crisis. High doses of diuretic are typically needed. This can
potentially lead to kidney failure though there is no alternative when the
heart is failing."
"In heart failure patients, when benazepril is commonly given in conjunction
with a diuretic (like furosemide), kidney parameters (BUN and Creatinine)
should be measured prior to benazepril use, again 3-7 days after benazepril
therapy has started, and periodically thereafter. Kidney function should
also be rechecked after any dose change in the heart failure patient."
"Benazepril is used in the treatment of high blood pressure
<http://www.marvistavet.com/html/body_high_blood_pressure.html> , in the
treatment of congestive heart failure, and in the treatment of renal
(kidney) protein-loss (such as glomerulonephritis). In the cat, amlodipine
<http://www.marvistavet.com/html/body_amlodipine_besylate.html> is felt to
have more reliable effect in treating high blood pressure but if the cat
also has renal protein-loss, then benazapril is generally preferred."
I'm going to ask the cardiologist about amlodipine, though I'm guessing
there is a good reason he prescribed benazepril instead. One of my other
cats has been taking amlodipine for high blood pressure for several years
with no apparent ill effects. She has idiopathic retinal detachment. Causing
blindness. I am now a proponent of having BP checked periodically on all
cats over the age of eight. Her retinal detachment could have been avoided.
You should be checking breaths per minute. My cardiologist said 14-16 is
great which is where my cat has been. She was around 20 after starting her
meds. Once it gets close to 30 there is a crisis. It also partly depends on
what the individual cats' normal BPM is. I certainly didn't know that for my
cat. The guideline is to count breathes in a 15 second interval and then
multiply by 4. I feel that counting for 30 and multiplying by 2 or counting
for 60 seconds is more accurate. The cat should be at rest preferably
sleeping. I do this when my cat is curled up in my lap while I am reading.
I hope this helps. I'm sure those with more experience have plenty more to
From: email@example.com [mailto:firstname.lastname@example.org] On
Behalf Of Janette
Sent: Thursday, March 21, 2013 1:33 PM
Subject: [FH] Zeke starting Furosemide
staring him on Furosemide. I noticed on the leaflett I got with the meds
that it can have an interaction with benazepril - which Zeke is on. Is there
a better diuretic that I should discuss with the vet? She said he's not in
congestive heart failure and will start progressivly declining. Any
particular things I should be watching for? Only thing she mentionted to me
was if he's open mouth breathing - he would need to go in and get put on
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