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kid asthma related to formaldehyde, G McGwin Jr, J Lienert, JI Kennedy Jr, Environmental Health Perspectives 2009.11.06 abstract: Rich Murray 2009.12.01

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  • Rich Murray
    kid asthma related to formaldehyde, G McGwin Jr, J Lienert, JI Kennedy Jr, Environmental Health Perspectives 2009.11.06 abstract: Rich Murray 2009.12.01
    Message 1 of 1 , Dec 1 8:55 PM
      kid asthma related to formaldehyde, G McGwin Jr, J Lienert, JI Kennedy Jr,
      Environmental Health Perspectives 2009.11.06 abstract: Rich Murray
      2009.12.01
      http://rmforall.blogspot.com/2009_12_01_archive.htm
      Tuesday, December 1, 2009
      http://groups.yahoo.com/group/aspartameNM/message/1590
      ____________________________________________________


      "The results indicate that there is a significant positive association
      between formaldehyde exposure and childhood asthma."

      http://ehp.niehs.nih.gov/docs/2009/0901143/abstract.pdf
      http://ehp.niehs.nih.gov/members/2009/0901143/0901143.pdf
      [ study accepted for publication, text still in process ]

      Formaldehyde Exposure and Asthma in Children:
      A Systematic Review
      Gerald McGwin, Jr., Jeffrey Lienert, and John I. Kennedy, Jr.
      Environmental Health Perspectives
      National Institutes of Health
      U.S. Department of Health and Human Services
      doi: 10.1289/ehp.0901143 (available at http://dx.doi.org/ )
      Online 6 November 2009
      ehponline.org

      Gerald McGwin, Jr. 1, Jeffrey Lienert 2, John I. Kennedy, Jr. 3,4
      1. Department of Epidemiology, School of Public Health,
      niversity of Alabama at Birmingham, Birmingham, AL
      2. Franklin and Marshall College, Lancaster, PA
      3. Department of Veterans Affairs Medical Center, Birmingham, AL
      4. Division of Pulmonary, Allergy & Critical Care Medicine,
      Department of Medicine, University of Alabama at Birmingham,
      Birmingham, AL
      Address for correspondence: Gerald McGwin, Jr., M.S., Ph.D.,
      922 7th Avenue South, Suite 120, Birmingham, AL 35294,
      mcgwin@... 205-975-3030 (ph.); 205-975-3040 (fax)

      ABSTRACT

      Objective:
      Despite multiple published studies regarding the association between
      formaldehyde exposure and childhood asthma, a consistent
      association has not been identified.
      This study reports the results of a systematic review of published
      literature in order to provide a more comprehensive picture of this
      relationship.

      Data Sources:
      Seven peer-reviewed studies providing quantitative results regarding the
      association between formaldehyde exposure and asthma in children were
      identified following a comprehensive literature search.
      There was heterogeneity across studies with respect to the definition of
      asthma (e.g., self-report, physician diagnosis).
      The majority of studies were crosssectional in nature.

      Data Extraction:
      For each study, an odds ratio (OR) and 95% confidence interval
      (CI) for asthma was either abstracted from published results or
      calculated based on the data provided.
      Characteristics regarding the study design and population were also
      abstracted.

      Data Synthesis:
      Fixed and random effects models were used to calculate pooled
      ORs and 95% CIs; measures of heterogeneity were also
      calculated.
      The results of a fixed effects model produced an
      OR of 1.03 (95% CI 1.02-1.04),
      and random effects model
      an OR of 1.17 (95% CI 1.01-1.36),
      both reflecting an increase of 10 microg/m3 of formaldehyde.
      Both the Q and I2 statistics indicated a moderate amount of
      heterogeneity.

      Conclusions:
      The results indicate that there is a significant positive association
      between formaldehyde exposure and childhood asthma.
      Given the largely cross-sectional nature of the studies underlying
      this meta-analysis, there remains a need for well-designed
      prospective epidemiologic studies.

      Key Words: asthma, children, epidemiology, formaldehyde,
      meta-analysis

      Acknowledgements and Grant Support: None

      Competing Interests Declaration:
      Dr. McGwin has been paid as an expert witness regarding
      the health effects of formaldehyde exposure.

      List of abbreviations and definitions used in manuscript:
      NIOSH (National Institute for Occupational Safety and Health)
      ppm (parts per million)
      ppb (parts per billion)
      OR (odds ratio)
      CI (confidence interval)

      Article Descriptor: asthma

      Outline of Section Headers
      Abstract
      Introduction
      Methods
      Results
      Discussion
      Conclusion
      References
      Tables
      Figure Legends
      Figures

      http://www.eyes.uab.edu/directory/mcgwin.html

      Gerald McGwin, Jr., PhD [ photo ]
      Professor and Vice Chair of Epidemiology

      Biography | Contact | Publications | Research Program

      Address:
      Department of Ophthalmology
      University of Alabama at Birmingham
      Callahan Eye Foundation Hospital
      700 S. 18th Street, Suite 609
      Birmingham, AL 35294-0009
      Phone: (205) 325-8117 Fax: (205) 325-8692
      E-mail: mcgwin@...

      Gerald McGwin, Jr. is originally from Portland, Maine.
      He received his B.S. degree from the University of Vermont (1993)
      majoring in Education.
      He received an M.S. degree in Health and Social Behavior from the
      Harvard University School of Public Health (1995) and
      a Ph.D. degree in Epidemiology from the
      University of Alabama at Birmingham (1998).
      Throughout his academic training, Dr. McGwin's research interests
      focused on injuries, particularly as they relate to elderly populations.

      Since 1998 Dr. McGwin has been on the faculty of the
      University of Alabama at Birmingham, where he is currently
      Professor and Vice Chair of Epidemiology with secondary
      appointments in the Departments of Ophthalmology and Surgery.
      His current research interests focus on the epidemiology of injuries,
      particularly motor vehicle collisions and burns,
      aging-related eye diseases, and lupus.

      John I. Kennedy, Jr., M.D.
      Associate Chief of Staff -- Acute & Specialty Care
      Chief, Medical Service, Birmingham VA Medical Ctr.
      UAB Hospital
      1802 6th Avenue South
      Birmingham, AL 35249
      (205) 934-9999
      Specialty: Allergy and Asthma, Pulmonary,
      Allergy and Critical Care Medicine
      Hospital Affiliations: UAB Hospital
      Faculty Title: Professor
      School of Medicine: Southwestern Medical School, 1981
      Internship: University of Alabama at Birmingham
      From 1981 To 1982
      Residencies: University of Alabama at Birmingham
      From 1982 To 1984
      Fellowships: University of Alabama at Birmingham
      From 1984 To 1986
      Certifications: American Board of Critical Care Medicine, 1987
      American Board of Internal Medicine, 1984
      American Board of Pulmonary Medicine, 1986
      Diseases Treated/Clinical Interests: Critical care medicine,
      interstitial lung disease, COPD, pulmonary thromboembolic disease.

      http://www.americanchronicle.com/articles/view/130603

      Asthma Linked to Formaldehyde Exposure in Clothing and
      Common Household Items
      Lourdes Salvador November 30, 2009

      There is a significant association between formaldehyde exposure
      and childhood asthma according to a recent scientific literature
      review by researchers Gerald McGwin, Jr., Jeffrey Lienert, and
      John I. Kennedy, Jr.

      Roughly 7% of adults and 9% of children suffer from asthma
      in the U.S.
      Seven peer-reviewed studies examined data showing an
      association between formaldehyde exposure and asthma in children.

      Many products in the indoor environment emit formaldehyde,
      including particle board, urea formaldehyde insulation, carpeting,
      and furniture.
      Clothing is also treated with formaldehyde.
      Mobile travel trailers provided by the Federal Emergency
      Management Agency (FEMA) to displaced Gulf Coast residents
      have also been shown to contain excessively high levels of
      formaldehyde.

      Exposure to formaldehyde can cause irritation of the eye, nose,
      throat and skin.
      Chronic exposure, such as that experienced in the home from
      treated furniture and carpets, has been linked with cancer and
      asthma.

      "The results of this study provide important evidence regarding the
      potential causal link between formaldehyde and asthma in children,
      says McGwin.

      Protect children from formaldehyde exposure next to the skin by
      buying organic and untreated clothing.
      Wrinkle resistant, stain resistant, and permanent press clothing are
      treated with formaldehyde and other potentially toxic chemicals.
      As a simple test on new clothing, fill a spray bottle with water and
      spray a bit on the garment.
      If it absorbs, the formaldehyde level is low.
      If it beads up and does not absorb, the formaldehyde level is high.

      Most furniture is sprayed with potentially toxic chemicals to resist
      mold, wrinkles, and stains.
      Fire retardants are applied as well.
      Look for organic and untreated furniture.
      Press wood generally contains a high amount of formaldehyde.
      Consider metal and stainless steel options and sew your own
      cushions.

      Bedding which has not been treated with fire retardants can only be
      purchased in the U.S. with a prescription from a doctor or
      chiropractor.
      If a prescription is not obtainable, consider an untreated mattress
      wrapped in wool, which meets the fire retardant laws in most states.

      Formaldehyde can also be found in some childhood vaccinations.
      Check the ingredients before vaccinating.
      There are often other brands which may have little or no
      formaldehyde.

      This article originally appeared in the MCS America News,
      December 2009 Issue
      http://mcs-america.org/december2009.pdf 41 pages, free newsletter
      To subscribe to this very informative free newsletter, send an email to:
      subscriptions@...
      admin@...
      For more articles on this topic, see: MCSA News.

      Copyrighted 2009 Lourdes Salvador & MCS America

      Lourdes Salvador

      Lourdes Salvador is the founder of MCS America, a science writer,
      and a social advocate for the greater awareness of environmental
      contamination, human toxicology, and propagation of
      multiple chemical sensitivity (MCS) as a disorder of organic
      biological origin induced by toxic environmental insults.

      The mission of MCS America (MCSA) is:

      1. To propagate medical, legal, and social recognition for
      multiple chemical sensitivity (MCS) as a disorder of organic
      biological origin induced by toxic environmental insults.

      2. To provide support and referral services to the individuals with
      multiple chemical sensitivity (MCS), chronic fatigue syndrome
      (CFS), fibromyalgia (FM), electrosensitivity, Gulf War Syndrome
      (GWS), autism, and other illnesses of environmental origin.

      3. To ensure that environmental toxicants are identified, reduced,
      regulated, and enforced through lobbying for effective legislation.

      MCS America serves as a partner for
      Environmental Education Week, a partner for the
      Collaborative on Health and the Environment (CHE),
      and a supporter for the American Cancer Society:
      Campaign for Smokefree Air.

      For more information, please visit:
      MCS America
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      All articles Copyrighted © 2007 - 2009 MCS America
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      ____________________________________________________


      methanol (11% of aspartame), made by body into formaldehyde in
      many vulnerable tissues, causes modern diseases of civilization,
      summary of a century of research, Woodrow C Monte PhD,
      Medical Hypotheses journal: Rich Murray 2009.11.15
      http://rmforall.blogspot.com/2009_11_01_archive.htm
      Sunday, November 15, 2009
      http://groups.yahoo.com/group/aspartameNM/message/1589

      older women drinking over 2 aspartame beverages daily had 30%
      decline kidney function in 11 years, Nurses Health Study, Julie Lin,
      Gary C Curhan, Brigham and Women's Hospital, Boston:
      Rich Murray 2009.11.02
      http://rmforall.blogspot.com/2009_11_01_archive.htm
      Monday, November 2, 2009
      http://groups.yahoo.com/group/aspartameNM/message/1588

      consider co-factors (methanol, formaldehyde, and protective folic
      acid), re UK FSA test of aspartame in candy bars on 50 reactors,
      Stephen L Atkin, Hull York Medical School:
      Rich Murray 2009.09.29
      http://rmforall.blogspot.com/2009_09_01_archive.htm
      Tuesday, September 29, 2009
      http://groups.yahoo.com/group/aspartameNM/message/1587

      details on 6 epidemiological studies since 2004 on diet soda
      (mainly aspartame) correlations, as well as 14 other mainstream
      studies on aspartame toxicity since summer 2005:
      Murray 2007.11.18
      http://rmforall.blogspot.com/2007_11_01_archive.htm
      Wednesday, November 14, 2007
      http://groups.yahoo.com/group/aspartameNM/message/1490
      ____________________________________________________


      Rich Murray, MA
      Boston University Graduate School 1967 psychology,
      BS MIT 1964, history and physics,
      1943 Otowi Road, Santa Fe, New Mexico 87505
      505-501-2298 rmforall@...

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