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metabolic syndrome is tied to diet soda, PL Lutsey, LM Steffen, J Stevens, Circulation 2008.01.22: role of formaldehyde and formic acid from methanol in wines, liquors, or aspartame?: Murray 2008.02.07

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  • rmforall@comcast.net
    metabolic syndrome is tied to diet soda, PL Lutsey, LM Steffen, J Stevens, Circulation 2008.01.22: role of formaldehyde and formic acid from methanol in wines,
    Message 1 of 1 , Feb 7, 2008
      metabolic syndrome is tied to diet soda,
      PL Lutsey, LM Steffen, J Stevens, Circulation 2008.01.22:
      role of formaldehyde and formic acid from methanol
      in wines, liquors, or aspartame?: Murray 2008.02.07
      http://rmforall.blogspot.com/2008_02_01_archive.htm
      Thursday, February 7, 2008
      http://groups.yahoo.com/group/aspartameNM/message/1513
      ____________________________________________________


      "But the one-third who ate the most fried food
      increased their risk by 25 percent,
      compared with the one-third who ate the least,
      and surprisingly, the risk of developing metabolic syndrome
      was 34 percent higher among
      those who drank one can of diet soda a day
      compared with those who drank none.

      "This is interesting," said Lyn M. Steffen,
      an associate professor of epidemiology
      at the University of Minnesota and a co-author
      of the paper, which was posted online in the journal
      Circulation on Jan. 22. "Why is it happening?
      Is it some kind of chemical in the diet soda,
      or something about the behavior of diet soda drinkers?""

      "The diet soda association was not hypothesized
      and deserves further study."

      [ See also:

      vinyl acetate, ethyl alcohol, or aspartame in womb increases
      later cancers in adults with lifetime exposure in many studies,
      M Soffritti et al, Ramazzini Foundation,
      Basic Clin. Pharm. Toxicol. 2008 Feb.:
      Rich Murray 2008.02.07
      http://rmforall.blogspot.com/2008_02_01_archive.htm
      Thursday, February 7, 2008
      http://groups.yahoo.com/group/aspartameNM/message/1511

      need to find safe levels for aspartame
      (methanol, formaldehyde, formic acid) via rapid, safe,
      low-cost, highly accurate and sensitive modern breath
      gas analysis: Claire Turner et al,
      Foundation for Innovative New Diagnostics:
      Rich Murray 2008.02.07
      http://rmforall.blogspot.com/2008_02_01_archive.htm
      Thursday, February 7, 2008
      http://groups.yahoo.com/group/aspartameNM/message/1512

      folic acid prevents neurotoxicity from formic acid, made by
      body from methanol impurity in alcohol drinks
      [ also 11 % of aspartame ], BM Kapur, PL Carlen,
      DC Lehotay, AC Vandenbroucke, Y Adamchik,
      U. of Toronto, 2007 Dec., Alcoholism Cl. Exp. Res.:
      Murray 2007.11.27
      http://rmforall.blogspot.com/2007_11_01_archive.htm
      Wednesday, November 27, 2007
      http://groups.yahoo.com/group/aspartameNM/message/1495 ]


      www.nytimes.com/2008/02/05/health/nutrition/05symp.html?ref=health

      Fitness & Science
      Vital Signs

      Symptoms: Metabolic Syndrome Is Tied to Diet Soda
      By Nicholas Bakalar
      Published February 5, 2008

      Researchers have found a correlation between drinking diet soda
      and metabolic syndrome -- � the collection of risk factors for
      cardiovascular disease and diabetes that include abdominal obesity,
      high cholesterol and blood glucose levels,
      and elevated blood pressure.

      The scientists gathered dietary information
      on more than 9,500 men
      and women ages 45 to 64
      and tracked their health for nine years.

      Over all, a Western dietary pattern �--
      high intakes of refined grains,
      fried foods and red meat -- was associated with an
      18 percent increased risk for metabolic syndrome,
      while a "prudent" diet dominated by
      fruits, vegetables, fish and poultry correlated with
      neither an increased nor a decreased risk.

      But the one-third who ate the most fried food
      increased their risk by 25 percent,
      compared with the one-third who ate the least,
      and surprisingly, the risk of developing metabolic syndrome
      was 34 percent higher among
      those who drank one can of diet soda a day
      compared with those who drank none.

      "This is interesting," said Lyn M. Steffen,
      an associate professor of epidemiology
      at the University of Minnesota and a co-author
      of the paper, which was posted online in the journal
      Circulation on Jan. 22. "Why is it happening?
      Is it some kind of chemical in the diet soda,
      or something about the behavior of diet soda drinkers?"

      Copyright 2008 The New York Times Company
      ____________________________________________________


      Published Online on January 22, 2008

      Circulation. 2008
      Published online before print January 22, 2008, doi:
      10.1161/CIRCULATIONAHA.107.716159
      Submitted on May 18, 2007
      Accepted on December 7, 2007

      Dietary Intake and the Development of the Metabolic Syndrome.
      The Atherosclerosis Risk in Communities Study
      Pamela L. Lutsey MPH, lutsey@...;
      Lyn M. Steffen PhD, MPH, RD*, steffen@...;
      and June Stevens PhD, MS, RD june_stevens@...;

      From the Division of Epidemiology and Community Health,
      University of Minnesota, School of Public Health,
      Minneapolis (P.L.L., L.M.S.),
      and Department of Nutrition,
      University of North Carolina, Chapel Hill (J.S.).

      Division of Epidemiology and Community Health,
      University of Minnesota,
      1300 South Second Street, Suite 300,
      Minneapolis, MN 55454, USA.
      lutsey@...;

      * To whom correspondence should be addressed.
      E-mail: steffen@...;

      Background
      The role of diet in the origin of metabolic syndrome
      (MetSyn) is not well understood;

      thus, we sought to evaluate the relationship
      between incident MetSyn and dietary intake
      using prospective data from 9514 participants
      (age, 45 to 64 years) enrolled in
      the Atherosclerosis Risk in Communities (ARIC) study.

      Methods and Results
      Dietary intake was assessed at baseline
      via a 66-item food frequency questionnaire.

      We used principal-components analysis to derive
      "Western" and "prudent"
      dietary patterns from 32 food groups
      and evaluated 10 food groups used in previous studies
      of the ARIC cohort.

      MetSyn was defined by American Heart Association guidelines.

      Proportional-hazards regression was used.

      Over 9 years of follow-up,
      3782 incident cases of MetSyn were identified.

      After adjustment for
      demographic factors, smoking, physical activity, and
      energy intake,
      consumption of a Western dietary pattern (Ptrend = 0.03)
      was adversely associated with incident MetSyn.

      After further adjustment for intake of
      meat, dairy, fruits and vegetables,
      refined grains, and whole grains,
      analysis of individual food groups revealed that
      meat (Ptrend under 0.001),
      fried foods (Ptrend = 0.02),
      and diet soda (Ptrend under 0.001)
      also were adversely associated with incident MetSyn,
      whereas dairy consumption (Ptrend = 0.006) was beneficial.

      No associations were observed between incident MetSyn
      and a prudent dietary pattern
      or intakes of whole grains, refined grains,
      fruits and vegetables, nuts,
      coffee, or sweetened beverages.

      Conclusions
      These prospective findings suggest that consumption
      of a Western dietary pattern, meat, and fried foods
      promotes the incidence of MetSyn, whereas
      dairy consumption provides some protection.

      The diet soda association was not hypothesized
      and deserves further study. PMID: 18212291

      Key words:
      dairy products, diet, food habits, meat, metabolic syndrome X

      www.sph.unc.edu/?option=com_profiles&profileAction=ProfDetail&profileId=1277

      June Stevens, PhD
      Website: http://myprofile.cos.com/stevensh31
      Email: june_stevens@...;
      Phone: 919-966-7218 Fax: 919-962-3265
      Address:
      University of North Carolina at Chapel Hill
      School of Public Health
      137 E Franklin St., Ste 400, CB#7461
      Chapel Hill, NC 27514

      Summary of Research Interests
      AICR/WCRF Distinguished Professor and Chair,
      Department of Nutrition;
      Professor, Department of Epidemiology.
      (PhD in Human Nutrition, Cornell,
      1986, MS, Penn State, 1980)
      Dr. Stevens is a nutrition epidemiologist
      with a large research program
      focusing on the causes, consequences,
      and prevention of obesity and
      different populations.
      She has special interests in minority health,
      anthropometry, and physical activity.
      Through her work at the
      Collaborative Studies Coordinating Center,
      she has access to obesity-related information
      from several large, multi-center studies.
      She is the Principal Investigator of the
      Coordinating Center for two national trials
      that examine obesity and physical activity
      in children and adolescents.
      Dr. Stevens is a member of
      the American Society for Nutritional Sciences,
      the American Heart Association Council on Epidemiology,
      the North American Society for the Study of Obesity,
      the International Association for the Study of Obesity (IASO)
      and the Society for Epidemiologic Research.
      Dr. Stevens is currently Vice President for Scientific Affairs
      of the IASO.
      She serves as a reviewer for
      the New England Journal of Medicine,
      the Journal of the American Medical Association,
      and the American Journal of Epidemiology,
      Obesity Research,
      and the International Journal of Obesity
      as well as several other journals.

      Educational Background
      1986 Cornell University PhD
      Human Nutrition, Minor Statistics
      1978 Pennsylvania State University MS
      Human Nutrition
      1975 Cleveland Metropolitan General Hospital RD
      Clinical Dietetics

      Barry M. Popkin , Professor of Nutrition,
      Carolina Population Center,
      University of North Carolina,
      123 West Franklin Street, Chapel Hill, NC
      27516-3997. E-mail: popkin@...;

      Kiyah J Duffey E-mail: kduffey@...;
      Address: 123 W. Franklin St. , CPC, University Square
      CB: 8120
      Telephone: (919) 966-1735
      Class: Graduate Doctorate
      College: School Of Public Health
      Degree: Doctor Of Philosophy
      Department: Nutrition (4660)
      Title: Research Assistant
      Department: Nutrition (4660)
      Home Address: 105 Fidelity St, B10, Carrboro,
      NC 275102617
      ____________________________________________________


      formaldehyde in FEMA trailers and other sources (aspartame,
      dark wines and liquors, tobacco smoke): Murray 2008.01.30
      http://rmforall.blogspot.com/2008_01_01_archive.htm
      Wednesday, January 30, 2008
      http://groups.yahoo.com/group/aspartameNM/message/1508


      The FEMA trailers give about the same amount of
      formaldehyde daily
      as from a quart of dark wine or liquor,
      or two quarts (6 12-oz cans) of aspartame diet soda,
      from their over 1 tenth gram methanol impurity
      (one part in 10,000),
      which the body quickly makes into formaldehyde --
      enough to be the major cause of
      "morning after" alcohol hangovers.

      Methanol and formaldehyde also result from many fruits
      and vegetables, tobacco and wood smoke, heater and vehicle
      exhaust, household chemicals and cleaners, cosmetics,
      and new cars, drapes, carpets, furniture, particleboard,
      mobile homes, buildings, leather...
      so all these sources add up and interact
      with many other toxic chemicals.

      BN Ames and LS Gold, 1998, have presented detailed
      information that there is no increase in recent decades for most
      cancers, and that common carcinogens do not result
      in significant exposures to the average human population.

      However, individuals are not average -- each person has a
      unique genetic makeup, resulting in a huge range
      of variation of vulnerability to specific chemicals,
      as is well evidenced in the case
      of methanol, formaldehyde, and formic acid,
      especially with regard to behavioral effects.

      Each is subject to very wide ranges of exposure levels.

      Many are in especially vulnerable groups, depending on diet,
      obesity, sex, exercise, life stress, age from conception to very old,
      severe toxic exposures, injuries, and diseases.

      It is clear that a variety of multiple chemical sensitivity syndromes
      do exist, often with remarkable hypersensitivity.

      Methanol, formaldehyde, and formic acid toxicity are unusual,
      in that humans are far more vulnerable than any other mammal,
      as much as ten to sixty-fold, which complicates the utility of animal
      data.

      The unusally long human life span also increases the role of
      long-term chronic low-level exposure.


      FEMA slow to safety test Katrina toxic trailers,
      Charles Babington, Associated Press -- 1 ppm formaldehyde
      in air is about half the daily dose from 3 cans aspartame
      diet soda and ten times the 1999 EPA alarm level
      for drinking water: Murray 2007.07.23
      http://groups.yahoo.com/group/aspartameNM/message/1455

      "Paulison said FEMA received "just over 200 complaints
      of strange odors including formaldehyde" in trailers
      and that 58 trailers were replaced
      "because of formaldehyde concerns."

      Occupants of five other trailers were moved to apartments,
      he said.

      Several lawmakers said FEMA should have seen the
      200 complaints
      as a sign of a much wider problem."


      1 ppm formaldehyde in air is half the daily dose
      from 3 cans aspartame diet soda
      and ten times the 1999 EPA alarm level for drinking water.

      J. D. Trasher et al in 1990 found many symptoms
      in 19 mobile home residents,
      living with 0.05 to 0.5 ppm formaldehyde.

      http://www.drthrasher.org/formaldehyde_1990.html full text
      Jack Dwayne Thrasher, Alan Broughton, Roberta Madison.
      Immune activation and autoantibodies in humans
      with long-term inhalation exposure to formaldehyde.
      Archives of Environmental Health. 1990; 45: 217-223.
      "Immune activation, autoantibodies, and anti-HCHO-HAS
      antibodies are associated
      with long-term formaldehyde inhalation."
      PMID: 2400243

      " The patients in our study had symptoms and complaints
      related to several organs, as described previously, (4,5,9)
      which were similar to symptoms
      of workers with multiple chemical sensitivity,(11) cacosmia,(12)
      and other chemical exposures. (13-15)

      We report on the differences in
      humoral and cell-mediated immunity in humans with long-term
      inhalation exposure to HCHO vs. asymptomatic students
      (controls) who experienced short-term, periodic exposure
      to the chemical. "

      " All patients in this study
      had sought continuous medical attention
      because of multiple organ symptoms
      involving the central nervous system (CNS)
      (headaches, memory loss, difficulty completing tasks, dizziness),
      upper- and lower-respiratory symptoms,
      skeletal-muscle complaints,
      and gastroenteritis.

      Three common symptoms were expressed:
      (1) and initial flu-like illness
      from which they had not fully recovered;
      (2) chronic fatigue,
      and (3) an olfactory sensitivity to ambient conditions
      containing low concentrations of chemicals. (4,9,11) "

      " (2.) Mobile home residents consisted
      of 19 patients (6 males, 13 females, mean age 41 +-20 y)
      who currently lived in mobile homes.

      The patients had lived in their environments for 2-7 y
      and reported multiple symptoms. (4,9)

      Measured HCHO concentrations
      ranged from 0.05 to 0.5 ppm
      at the time blood samples were taken. "


      FEMA found 1.2 ppm formaldehyde in April 2005
      in one of over 120,000 mobile homes
      supplied for recent hurricane victims --
      75 times more than the
      0.016 ppm level set for 8-hour working days
      by the National Institute for Occupational Safety and Health
      for workers to be required to wear respirators.

      http://www.arb.ca.gov/toxics/tac/appendxc.htm

      1 ppm FA in air = 1.23 mg/cubic meter,
      so breathing 20 cubic meters would retain
      about 20 mg FA daily,
      ten times the 1999 EPA alarm level for drinking water.

      Dark wines and liquors, as well as aspartame,
      provide similar levels of methanol, above 120 mg daily,
      for long-term heavy users, 2 L daily, about 6 cans.

      Within hours, methanol is inevitably largely turned into
      formaldehyde,
      and thence largely into formic acid --
      the major causes of the dreaded symptoms
      of "next morning" hangover.

      Fully 11% of aspartame is methanol --
      1,120 mg aspartame in 2 L diet soda,
      almost six 12-oz cans,
      gives 123 mg methanol (wood alcohol).

      If 30% of the methanol is turned into formaldehyde,
      the amount of formaldehyde, 37 mg,
      is 18.5 times the USA EP alarm limit
      for daily formaldehyde in drinking water,
      2.0 mg in 2 L average daily drinking water.

      Medicine has to consider that the many sources of methanol
      and formaldehyde are additive co-factors.

      http://groups.yahoo.com/group/aspartameNM/message/1286
      methanol products (formaldehyde and formic acid)
      are main cause of alcohol hangover symptoms
      [same as from similar amounts of methanol, the 11% part of
      aspartame]: YS Woo et al, 2005 Dec: Murray 2006.01.20

      http://groups.yahoo.com/group/aspartameNM/message/1143
      methanol (formaldehyde, formic acid) disposition:
      Bouchard M et al, full plain text, 2001:
      substantial sources are degradation of fruit pectins,
      liquors, aspartame, smoke: Murray 2005.04.02


      "... aspartame. It's perfectly safe," eminent diabetes MD S. Kalani
      Brady -- er, Doctor, RX for ignorance, 3 days earnest study of
      recent 2 years of mainstream research by groups independent of
      vested interests: Murray 2008.01.27
      http://rmforall.blogspot.com/2008_01_01_archive.htm
      Sunday, January 27, 2008
      http://groups.yahoo.com/group/aspartameNM/message/1507

      details on 6 epidemiological studies since 2004 on diet soda (mainly
      aspartame) correlations, as well as 14 other mainstream studies on
      aspartame toxicity since summer 2005: Murray 2007.11.27
      http://rmforall.blogspot.com/2007_11_01_archive.htm
      Wednesday, November 14, 2007
      http://groups.yahoo.com/group/aspartameNM/message/1490

      Hawaiian aspartame ban bills in House and Senate challenge
      corporate clout, Sen. J. Kalani English & Suzanne Chun Oakland,
      Rep. Calvin K.Y. Say & Mele Carroll: Murray 2008.01.25
      http://rmforall.blogspot.com/2008_01_01_archive.htm
      Friday, January 25, 2008
      http://groups.yahoo.com/group/aspartameNM/message/1505

      www.capitol.hawaii.gov/site1/house/members/rep13.asp

      Mele Carroll
      13th Representative District
      Hawaii State Capitol, Room 405
      415 South Beretania Street
      Honolulu, HI 96813
      Phone 808-586-6790; fax 808-586-6779
      From Maui, toll free 984-2400 + 66790
      From Molokai and Lanai,
      toll free 1-800-468-4644 + 66790
      E-mail repcarroll@...;

      http://groups.yahoo.com/group/aspartameNM/message/1426
      ASDA (unit of Wal-Mart Stores WMT.N)
      and Marks & Spencer
      will join Tesco and also Sainsbury to ban and limit
      aspartame, MSG, artificial flavors dyes preservatives additives,
      trans fats, salt "nasties" to protect kids from ADHD:
      leading UK media: Murray 2007.05.15

      http://groups.yahoo.com/group/aspartameNMmessage/1451
      Artificial sweeteners (aspartame, sucralose) and coloring
      agents will be banned from use in newly-born and baby foods,
      the European Parliament decided: Latvia ban in schools 2006:
      Murray 2007.07.12

      "Of course, everyone chooses, as a natural priority,
      to enjoy peace, joy, and love
      by helping to find, quickly share, and positively act
      upon evidence about healthy and safe
      food, drink, and environment."

      Rich Murray, MA Room For All rmforall@...
      505-501-2298 1943 Otowi Road, Santa Fe, New Mexico 87505

      http://groups.yahoo.com/group/aspartameNM/message/1469
      highly toxic formaldehyde, the cause of alcohol hangovers,
      is made by the body from 100 mg doses of methanol
      from dark wines and liquors, dimethyl dicarbonate,
      and aspartame: Murray 2007.08.31

      http://RMForAll.blogspot.com new primary archive

      http://groups.yahoo.com/group/aspartameNM/messages
      group with 120 members, 1,513 posts in a public archive
      ______________________________________________________


      www.washingtonpost.com/wp-dyn/content/article/2008/01/28/AR2008012802429.html

      washingtonpost.com > Politics

      2008 Politics � Candidates | Issues |
      Lawmakers Fault FEMA on Trailers

      washingtonpost.com readers have posted 27comments
      about this item.
      View All Comments �

      From News Services and Staff Reports
      Tuesday, January 29, 2008; Page A03

      Lawmakers Fault FEMA on Trailers

      Democratic leaders of a House science subcommittee alleged
      yesterday that the Federal Emergency Management Agency
      manipulated scientific research into the potential danger posed
      by a toxic gas emitted in trailers still housing tens of thousands
      of survivors of hurricanes Katrina and Rita.

      FEMA "ignored, hid and manipulated government research
      on the potential impact of long-term exposure to formaldehyde"
      on Katrina and Rita victims now living in the FEMA trailers,
      the congressmen wrote in a letter to
      Homeland Security Secretary Michael Chertoff,
      whose department includes FEMA.

      Reps. Brad Miller (N.C.) and Nick Lampson (Tex.) cited agency
      documents given to Congress in alleging that the federal
      Centers for Disease Control and Prevention --
      generally considered a repository
      of nonpartisan scientific expertise --
      was "complicit in giving FEMA precisely what they wanted"
      to suppress the adverse health effects.

      The lawmakers said the CDC's
      Agency for Toxic Substances and Disease Registry
      ignored one of its experts, Christopher T. De Rosa,
      after he informed FEMA there was no "safe level" of long-term
      exposure.

      They said FEMA bypassed that opinion and "shopped"
      the agency for its desired recommendation
      to study only short-term exposure.

      "Any level of exposure to formaldehyde may pose a cancer risk,
      regardless of duration," De Rosa wrote in a Feb. 27, 2007
      letter to a FEMA lawyer, recently obtained by a
      House Science and Technology investigative subcommittee
      that Miller chairs. "Failure to communicate this issue
      is possibly misleading and a threat to public health."

      De Rosa wrote the letter after learning that the CDC bypassed
      his office to produce a Feb. 1, 2007, report for FEMA that did
      not consider long-term exposure risks, contradicting his
      recommendation to the agency in June 2006.

      "Honest scientific studies don't start with the conclusion,
      and then work backwards from there," Miller said.

      FEMA said the health agency's report last February did not
      address long-term health effects
      but rather concerned ways to avoid toxic
      exposure to formaldehyde.

      "FEMA did not suppress or inappropriately influence
      any report," agency spokesman James McIntyre said.

      More than 40,000 trailers are still being used by families
      displaced by Katrina in August 2005 and Rita weeks later.

      FEMA announced last July that it would test occupied trailers,
      after congressional investigators disclosed that the agency
      had suppressed warnings for more than a year
      from its field workers
      about health problems experienced by Katrina survivors.

      Tests on 500 trailers, finally begun last month,
      are being performed by CDC, the lawmakers noted.
      "The Committee is concerned about
      the independence and scientific integrity
      of any indoor air testing for formaldehyde levels
      in these trailers done under the auspices of FEMA,"
      Miller and Samson wrote.

      "For those who are too poor to live elsewhere,
      FEMA's position remains as it was in 2006:
      there are no possible adverse health effects
      that can't be cured by opening the windows," they added.

      1/29/2008 12:28:27 PM rhfalk wrote:

      It is not as though formaldehyde was not known to be present in
      mobile homes.

      In a scientific paper published in 1998
      (Biotherapy 11: 205-220, The Causes and Prevention of Cancer:
      The Role of the Environment), Bruce Ames and Lois Gold,
      eminent researchers at the University of California, Berkeley,
      clearly indicated that this was the case.

      There is nothing mysterious about formaldehyde or a great deal of
      other compounds that have potential carcinogenic effects as listed
      in this excellent research paper.

      Lots of rather common things have the potential to cause cancer.

      Ames and Gold's paper can be found at
      http://potency.berkeley.edu/pdfs/Biotherapy1998.pdf

      Section of Cardiology, Boston University School of Medicine,
      Boston, MA 02118, USA. rfalk@...;

      Last name Derosa
      First name Christopher
      Middle name T.
      Agency ATSDR
      Organization DHHS/ATSDR/OA/OD
      Job title ACT. SPECIAL ASST FOR TOXICOLOGY
      Building CCTR
      Duty station Atlanta GA 30329
      Mail stop E28
      Phone 404.498.0284 Fax 404.498.0083
      Internet e-mail christopher.derosa@...;
      ______________________________________________________


      http://potency.berkeley.edu/pdfs/Biotherapy1998.pdf

      Biotherapy 11: 205-220, 1998.
      � 1998 Kluwer Academic Publishers. Printed in the Netherlands.
      The Causes and Prevention of Cancer: The Role of Environment
      Bruce N. Ames 1
      and Lois Swirsky Gold 2
      1 Department of Molecular and Cell Biology,
      University of California, Berkeley, CA 94720-3202;
      2 Life Sciences Division,
      E.O. Lawrence Berkeley National Laboratory,
      Berkeley, California 94720

      Nutrition and Metabolism Center,
      Children's Hospital of Oakland
      Research Institute, Oakland, CA 94609, USA.
      bames@...;

      University of Washington School of Public Health
      and Community Medicine, Department of Epidemiology,
      Seattle, Washington, USA. goldl@...;
      ______________________________________________________


      Seizures and hyponatremia after excessive intake of diet coke,
      LJ Mortelmans, M Van Loo, HG De Cauwer,
      K Merlevede, Klina General Hospital,
      Brasschaat, Belgium, EJEM 2008 Feb:
      Mark D. Gold critique: Murray 2008.01.10
      http://rmforall.blogspot.com/2008_01_01_archive.htm
      Thursday, January 10, 2008
      http://groups.yahoo.com/group/aspartameNM/message/1502


      See also:
      possible neurologic effects of aspartame, TJ Maher,
      RJ Wurtman, Environ. Health Persp. 1987 Nov, full text:
      other seizure reports re
      aspartame, methanol, formaldehyde, formic acid:
      Murray 2008.01.10
      http://rmforall.blogspot.com/2008_01_01_archive.htm
      Thursday, January 10, 2008
      http://groups.yahoo.com/group/aspartameNM/message/1501


      Eur J Emerg Med. 2008 Feb; 15(1): 51.
      Seizures and hyponatremia after excessive intake of diet coke.
      Mortelmans LJ, Luc.mortelmans@...;
      Van Loo M,
      De Cauwer HG, haralddecauwer@...;
      Merlevede K. Karen.Merlevede@...;
      Departments of
      a Emergency Medicine
      b Neurology,
      Klina General Hospital, Brasschaat, Belgium.

      We describe a case of epileptic seizures after a massive intake of
      diet coke.

      Apart from the hyponatremia due to water intoxication the
      convulsions can be potentiated by the high dose of caffeine and
      aspartame from the diet coke.

      To our knowledge this is the first report of seizures due to
      excessive diet coke intake. PMID: 18180668


      Methyl alcohol ingestion as a model etiologic agent in
      multiple sclerosis, WC Monte, D Glanzman, C Johnston;
      Methanol induced neuropathology in the mammalian
      central nervous system, Woodrow C. Monte, Renee Ann Zeising,
      both reports 1989.12.04: Murray 2007.12.28
      http://rmforall.blogspot.com/2007_12_01_archive.htm
      Friday, December 28 2007
      http://groups.yahoo.com/group/aspartameNM/message/1499

      [ These seminal 1989 studies by Prof. Woodrow C. Monte
      are also given in this previous post,
      along his two recent comprehensive reviews:

      role of formaldehyde, made by body from methanol from foods
      and aspartame, in steep increases in fetal alcohol syndrome,
      autism, multiple sclerosis, lupus, teen suicide, breast cancer,
      Nutrition Prof. Woodrow C. Monte, retired,
      Arizona State U., two reviews, 190 references supplied,
      Fitness Life, New Zealand 2007 Nov, Dec:
      Murray 2007.12.26
      http://rmforall.blogspot.com/2007_12_01_archive.htm
      Wednesday, December 26 2007
      http://groups.yahoo.com/group/aspartameNM/message/1498 ]

      folic acid prevents neurotoxicity from formic acid, made by
      body from methanol impurity in alcohol drinks
      [ also 11 % of aspartame ], BM Kapur, PL Carlen,
      DC Lehotay, AC Vandenbroucke, Y Adamchik,
      U. of Toronto, 2007 Dec., Alcoholism Cl. Exp. Res.:
      Murray 2007.11.27
      http://rmforall.blogspot.com/2007_11_01_archive.htm
      Wednesday, November 27, 2007
      http://groups.yahoo.com/group/aspartameNM/message/1495

      http://groups.yahoo.com/group/aspartameNM/message/1340
      aspartame groups and books: updated research review of
      2004.07.16: Murray 2006.05.11

      http://groups.yahoo.com/group/aspartameNM/message/1453
      Souring on fake sugar (aspartame), Jennifer Couzin,
      Science 2007.07.06: 4 page letter to FDA from 12 eminent
      USA toxicologists re two Ramazzini Foundation
      cancer studies 2007.06.25: Murray 2007.07.18

      http://groups.yahoo.com/group/aspartameNM/message/1341
      Connecticut bans artificial sweeteners in schools, Nancy Barnes,
      New Milford Times: Murray 2006.05.25

      http://groups.yahoo.com/group/aspartameNM/message/1369
      Bristol, Connecticut, schools join state program to limit artificial
      sweeteners, sugar, fats for 8800 students, Johnny J Burnham,
      The Bristol Press: Murray 2006.09.22

      Devra Lee Davis, U. Pittsburgh Cancer Institute,
      rejects aspartame -- Luke Ravenstahl, Mayor,
      drinks 12 cans Diet Pepsi daily:
      accurate warning by Ronald K. Frazer:
      Murray 2008.01.13
      http://rmforall.blogspot.com/2008_01_01_archive.htm
      Sunday, January 13, 2008
      http://groups.yahoo.com/group/aspartameNM/message/1503

      http://en.wikipedia.org/wiki/Aspartame_controversy
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