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highly toxic formaldehyde, the cause of alcohol hangovers, is made by the body from 100 mg doses of methanol from dark wines and liquors, dimethyl dicarbonate, and aspartame: Murray 2007.08.31

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  • Rich Murray
    highly toxic formaldehyde, the cause of alcohol hangovers, is made by the body from 100 mg doses of methanol from dark wines and liquors, dimethyl dicarbonate,
    Message 1 of 1 , Aug 31, 2007
      highly toxic formaldehyde, the cause of alcohol hangovers, is made by
      the body from 100 mg doses of methanol from dark wines and liquors,
      dimethyl dicarbonate, and aspartame: Murray 2007.08.31

      DMDC: Dimethyl dicarbonate 200mg/L in drinks adds methanol 98 mg/L
      ( becomes formaldehyde in body ): EU Scientific Committee on Foods
      2001.07.12: Murray 2004.01.22


      "...DMDC was evaluated by the SCF in 1990 and considered acceptable for
      the cold sterilization of soft drinks and fruit juices at levels of
      addition up to 250 mg/L (1)
      ...DMDC decomposes primarily to CO2 and methanol ...

      [ Note: Sterilization of bacteria and fungi is a toxic process,
      probably due to the inevitable conversion in the body of methanol
      into highly toxic formaldehyde and then formic acid. ]

      The use of 200 mg DMDC/L would add 98 mg/L of methanol to wine which
      already contains an average of about 140 mg/L from natural sources.

      A healthy person metabolises 1500 mg methanol/hr without any
      physiological problems and this should be compared to the amount of up
      to 240 mg/L methanol in wine, treated with DMDC up to 200 mg/L.

      Metabolism of the amounts of methanol resulting from consumption of wine
      containing such levels is therefore well within the capacity of the
      human body.
      Thus consumption of even large quantities of wine would not pose any
      hazards from methanol.


      The formation of methanol and other reaction products following the use
      of DMDC for the treatment of alcoholic beverages and wine is similar to
      that formed in non-alcoholic beverages.
      Therefore the previous opinion on the use of DMDC for non-alcoholic
      beverages (1) is equally applicable to wines treated with DMDC."

      However, research shows that the methanol in dark wines and liquors is
      made into formaldehyde by the body, causing the toxic symptoms of hangovers.

      methanol products (formaldehyde and formic acid) are main cause of
      alcohol hangover symptoms [same as from similar amounts of methanol, the
      11% part of aspartame]: YS Woo et al, 2005 Dec: Murray 2006.01.20

      Addict Biol. 2005 Dec;10(4): 351-5.
      Concentration changes of methanol in blood samples during
      an experimentally induced alcohol hangover state.
      Woo YS, Yoon SJ, Lee HK, Lee CU, Chae JH, Lee CT, Kim DJ.
      Chuncheon National Hospital, Department of Psychiatry,
      The Catholic University of Korea, Seoul, Korea.
      http://www.cuk.ac.kr/eng/ sysop@...
      Songsin Campus: 02-740-9714 Songsim Campus: 02-2164-4116
      Songeui Campus: 02-2164-4114
      http://www.cuk.ac.kr/eng/sub055.htm eight hospitals

      [ Han-Kyu Lee ]

      A hangover is characterized by the unpleasant physical and mental
      symptoms that occur between 8 and 16 hours after drinking alcohol.

      After inducing experimental hangover in normal individuals,
      we measured the methanol concentration prior to
      and after alcohol consumption
      and we assessed the association between the hangover condition
      and the blood methanol level.

      A total of 18 normal adult males participated in this study.

      They did not have any previous histories of psychiatric
      or medical disorders.

      The blood ethanol concentration prior to the alcohol intake
      (2.26+/-2.08) was not significantly different from that
      13 hours after the alcohol consumption (3.12+/-2.38).

      However, the difference of methanol concentration
      between the day of experiment (prior to the alcohol intake)
      and the next day (13 hours after the alcohol intake)
      was significant (2.62+/-1.33/l vs. 3.88+/-2.10/l, respectively).

      A significant positive correlation was observed
      between the changes of blood methanol concentration
      and hangover subjective scale score increment when covarying
      for the changes of blood ethanol level (r=0.498, p<0.05).

      This result suggests the possible correlation of methanol
      as well as its toxic metabolite to hangover. PMID: 16318957

      [ The toxic metabolite of methanol is formaldehyde, which in turn
      partially becomes formic acid -- both potent cumulative toxins
      that are the actual cause of the toxicity of methanol.]

      methanol (formaldehyde, formic acid) disposition: Bouchard M et al, full
      plain text, 2001: substantial sources are degradation of fruit pectins,
      liquors, aspartame, smoke: Murray 2005.04.02

      Fully 11 % of aspartame is methanol -- 1,120 mg aspartame
      in 2 L diet soda, almost six 12-oz cans, gives 123 mg methanol
      (wood alcohol). The methanol is immediately released
      into the body after drinking .
      Within hours, the liver turns much of the methanol into formaldehyde,
      and then much of that into formic acid, both of which in time
      are partially eliminated as carbon dioxide and water.

      However, about 30 % of the methanol remains in the body
      as cumulative durable toxic metabolites of formaldehyde
      and formic acid -- 37 mg daily,
      a gram every month, accumulating in and affecting every tissue.

      If only 10 % of the methanol is retained daily as formaldehyde,
      that would give 12 mg daily formaldehyde accumulation -- about
      60 times more than the 0.2 mg from 10 % retention
      of the 2 mg EPA daily limit for formaldehyde in drinking water.

      Bear in mind that the EPA limit for formaldehyde in drinking water is
      1 ppm, or 2 mg daily for a typical daily consumption of 2 L of water.

      ATSDR: EPA limit 1 ppm formaldehyde in drinking water July 1999:
      Murray 2002.05.30

      This long-term low-level chronic toxic exposure leads to typical
      patterns of increasingly severe complex symptoms,
      starting with headache, fatigue, joint pain, irritability, memory loss,
      rashes, and leading to vision and eye problems, and even seizures.
      In many cases there is addiction. Probably there are immune system
      disorders, with a hypersensitivity to these toxins and other chemicals.

      13 mainstream research studies in 24 months showing aspartame
      toxicity, also 3 relevant studies on methanol and formaldehyde: Murray

      Formaldehyde induced urticarial vasculitis in male medical student, age
      40, Michael Pellizzari, Gillian Marshman, Flinders U., Australasian J.
      Dermatol. 2007 Aug: Murray 2007.08.29

      Souring on fake sugar (aspartame), Jennifer Couzin,
      Science 2007.07.06: 4 page letter to FDA from 12 eminent
      USA toxicologists re two Ramazzini Foundation
      cancer studies 2007.06.25: Murray 2007.07.18

      aspartame bans, tis more an avalanche than a trend...: Rich Murray

      So far, USA print and broadcast media are deaf, blind, and dumb,
      regarding recent major bans of aspartame and MSG in the UK and EU.

      The EU Parliament voted July 12 to ban artificial sweeteners
      in newly born and infant foods.

      On May 15 four huge UK supermarket chains announced bans
      of aspartame and MSG, food dyes, and many additives
      to protect kids from ADHD --
      Sainsbury, Tesco, Marks & Spencer, and ASDA, a unit of WalMart.

      May 31: Coca-Cola and the much larger Cargill Inc.,
      after years of secret development, with 24 patents,
      will soon sell rebiana (stevia) in drinks and food
      in the many nations where it is approved as a sweetener --
      for decades a major sweetener in Japan, China, Korea, Taiwan,
      Thailand, Malasia, Saint Kitts, Nevis,
      Brazil, Peru, Paraguay, Uruguay, and Israel,
      and an approved supplement in USA, Australia, and Canada,
      according to Wikipedia.

      recent research and news re aspartame and stevia: Murray 2007.08.16

      "Of course, everyone chooses, as a natural priority,
      to actively find, quickly share, and positively act
      upon the facts about healthy and safe food, drink,
      and environment."

      Rich Murray, MA Room For All rmforall@...
      505-501-2298 1943 Otowi Road, Santa Fe, New Mexico 87505

      group with 82 members, 1,469 posts in a public,
      searchable archive http://RMForAll.blogspot.com

      Aspartame Controversy, in Wikipedia democratic
      encyclopedia, 72 references (including AspartameNM # 864
      and 1173 by Murray, brief fair summary of much more research:
      Murray 2007.01.01

      Artificial sweeteners (aspartame, sucralose) and coloring
      agents will be banned from use in newly-born and baby foods,
      the European Parliament decided: Latvia ban in schools 2006:
      Murray 2007.07.12

      stevia to be approved and cyclamates limited by
      Food Standards Australia New Zealand:
      JMC Geuns critiques of two recent stevia studies by Nunes:
      Murray 2007.05.29

      more from The Independent, UK, Martin Hickman, re ASDA
      (unit of Wal-Mart Stores) and Marks & Spencer ban of
      aspartame, MSG, artificial chemical additives and dyes
      to prevent ADHD in kids: urray 2007.05.16

      ASDA (unit of Wal-Mart Stores WMT.N) and Marks & Spencer
      will join Tesco and also Sainsbury to ban and limit
      aspartame, MSG, artificial flavors dyes preservatives additives,
      trans fats, salt "nasties" to protect kids from ADHD:
      leading UK media: Murray 2007.05.15

      Coca-Cola and Cargill Inc., after years of development,
      with 24 patents, will soon sell rebiana (stevia)
      in drinks and foods: Murray 2007.05.31

      www.ncbi.nlm.nih.gov/sites/entrez search PubMed
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