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565Studies suggest new key to 'switching off' hypertension + Vacancies

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  • Pharmacists_coffee
    Jul 26, 2013

    Pharmacists_coffee magazine
    Edition No. 517, year 6

    July 26, 2013
    Today's edition sent to:
    31,241 Arabian Pharmacists

    Find Valuable attachment
    �"Time Management"
    ��may find attachment at the end of e-mail


    Medicine of the week
    Propranolol is a sympatholytic non-selective beta blocker. Sympatholytics are used to treat hypertension, anxiety and panic. It was the first successful beta blocker developed. Propranolol is available in generic form as Propranolol Hydrochloride; marketed in India under brand names like Ciplar and Ciplar LA by Cipla, also other brands from AstraZeneca and Wyeth under brand names Inderal, Inderal LA, Avlocardyl, Deralin, Dociton, Inderalici, InnoPran XL, Sumial, Anaprilinum, Bedranol SR (Sandoz).
    Propranolol is a non-selective beta blocker, that is, it blocks the action of epinephrine and norepinephrine on both β1- and β2-adrenergic receptors. It has little intrinsic sympathomimetic activity (ISA) but has strong membrane stabilizing activity (only at high blood concentrations, e.g. overdosage). Research has also shown that propranolol has inhibitory effects on the norepinephrine transporter and/or stimulates norepinephrine release (present experiments have shown that the concentration of norepinephrine is increased in the synapse but do not have the ability to discern which effect is taking place). Since propranolol blocks β-adrenoceptors, the increase in synaptic norepinephrine only results in α-adrenergic activation, with the α1-adrenoceptor being particularly important for effects observed in animal models. Therefore, some have suggested that it be looked upon as an indirect α1 agonist as well as a β antagonist. Probably owing to the effect at the α1-adrenoceptor, the racemic and the individual enantiomers of propranolol have been shown to substitute for cocaine in rats, with the most potent enantiomer being S-(-)-propranolol. In addition, some evidence suggests that propranolol may function as a partial agonist at one or more serotonin receptors (possibly 5-HT1B).
    Both enantiomers of the drug have a local anesthetic (topical) effect, which is normally mediated by blockade of voltage-gated sodium channels. Few studies have demonstrated propranolol's ability to block cardiac, neuronal, and skeletal voltage-gated sodium channels, accounting for its known "membrane stabilizing effect" and anti-arrhythmic and other central nervous system effects.


    Male and Female Medical Rep for Central Area

    Urgently required for a Multinational Pharmaceutical company
    Male and Female Medical Rep based in Riyadh
    For the male position :
    1. Age not more than 28
    2. Should be Pharmacist
    3. Should has transferable Iqama
    4. should has at least 1 year experience in the Saudi market
    For the Female position :
    1. Has the ability to work in 2 split shifts
    Kindly send your CV with a recent photo to the below email address

    Pharmacist Free Lancer / Part Time - Saudi Arabia only

    Pharma Dynamics Leading Regional Research Agency
    We looking for�part time pharmacist�to apply different marketing research methodologies through face to face interviews with
    Physicians,�Patients & Pharmacist in all KSA Regions & Cities
    Our work is by project and average project duration 15 days�with excellent, excellent package
    1. Pharmacist
    2. Experience in KSA at least 2 Years
    3. Excellent Communications skills and time management
    4. Excellent Package
    Please send your updated CV with recent photo to:


    NUTRIBIO A Multinational Nutritional company seeking for a qualified candidates to join our expanding team in the western, southern area .
    Product Specialist �Male & Female �in the following areas :
    1- Jeddah����� ref. code���(JED)
    2- Taif���������� �ref. code� �(TAIF)
    3- Makkah�� �ref. code� �(MAK)
    4- Madinah �ref.code�� �(MAD)
    5- Gazan������ ref. code� �(GAZ)
    6- Abha�������� ref. code� �(Abha)
    The candidate should have the following criteria:
    1. Pharmacist, Vet or science.
    2- TWO years experience in international company is preferred , NUTRITIONAL experience is preferred
    3- Age not more than 30 years old .
    3. Fluently Speaks, Reads and Writes English .
    4-Valid Saudi Driving license
    5. Excellent problem solving, communication skills, hard worker, problem solver, independence and presentation skills
    6-Transferable Iqama is a MUST
    7- Area experience is preferred
    Please send your resume to:
    with the reference code in the subject .
    N.B: C.V. from outside KSA will be rejected

    Med. Rep. in KSA

    We are a fast growing international pharmaceutical organization with attractive opportunities for career development.
    We are currently looking for qualified candidates to join our expanding team that are able to execute an effective promotional sales plan, build and develop business relationships in the following positions:
    *Medical Representatives " Ref. MR" All Kingdom . .
    Applicant should have the following criteria:
    1-Transferable Iqama.
    2-Medical background: Pharmacist , Physicians , Vet or Science.
    3- At least 2 years experience in the same position in the same area.
    4-Skills: Interpersonal skill , Communication skills , Presentation skills and negotiation skills.
    5-Qualifications: Excellent command of English , excellent computer user.
    6- Proved track record of success.
    We offer Attractive Packages including competitive salaries , Health insurance & achievement incentives.
    If you interested send your C.V. with recent photo on the following Email:
    Pharmacist required
    Medical center in Jeddah needs pharmacist for 2 months "i3ara"
    Tel: 0530732870

    Male medical representative in Riyadh

    Novalac�a French�nutritional�company
    is looking for
    A male medical representative in Riyadh �( Ref: Riyadh)
    With the following criteria
    - pharmacist, physician or�veterinarian
    - minimum one year experience
    - Valid ksa driving license
    - Transferable Iqama
    - age below 30 years
    kindly send your C.V to

    Multinational dental comapny in KSA

    Need medical representatives for Saudi Arabia
    Requirements are:
    • Dentist & Vet & science & pharmacist.
    • Male &� female
    • Age has to be < 30 years
    • Riyadh only
    • One or two years of similar experience in KSA market.
    • Excellent command of English language (oral and written).
    • Excellent computer skills.
    For interested applicant send cv to

    Middle East Jamjom co.

    due to our expansion in the central area to matching our strategy plan for the current year..we are looking for hiring product specialist with following criteria:-
    - age not exceed 30 yrs.
    -must hold B.sc of pharmacy,vet or science.
    -must have 2 yrs experience at least in the saudi pharmaceutical market perfered central area.
    -valid driving license and transferable iqama.
    right candidates should send their cv at maxmium 10 days at the following email:

    Multinational Cosmeceutical company - KSA

    Multinational Cosmeceutical company seeking to recruit qualified candidates for the expansion at Saudi Arabia
    Jeddah medical and sales representatives ( Male and Female ) Ref : Jeddah MR
    Riyadh medical and sales representatives ( Male and Female ) Ref : Riyadh MR
    Dammam medical and sales representatives ( Male and Female ) Ref : Dammam MR
    We offer an attractive salary,transportation,housing, medical insurance and incentive
    only saudi resident.
    All applications will be treated with strict confidentiality
    If your qualifications met our need please send your C.V at e-mail
    or fax
    02 639 82 87

    Female medical rep in Riyadh and Dammam for a multinational nutritional company

    Female Medical rep for Riyadh Area �Ref : Riyadh
    Female Medical rep for Dammam area �Ref : Dammam
    with following criteria
    Pharmacist, veterinarian or�physician
    minimum one year experience as a medical representative
    age below 30 years
    kindly send your C.V to :

    Exciting career opportunity in Saudi Arabia
    We are a leading research-based global nutrition company, and are committed to being recognized as one of the best nutritional companies in the world through quality, integrity, and excellence in products and people. We are in the process of further expanding our operations across the region and are seeking:
    Medical representatives - Saudi Arabia
    ·�������� Promote and provide approved information to HCP on company products
    ·�������� Represent the company in front of: physicians, pharmacists and other healthcare professionals
    ·�������� Develop and maintain a high standard of selling skills and product knowledge ensuring that all activities comply with highest standards
    ·�������� Develop strong customer relationships by upholding, the company values and brands
    ·�������� Building the company strong market position through various marketing activities
    Please read our requirements carefully before applying:
    The successful candidate(s) must fulfill the following requirements:
    ·�������� Holder of BSc in pharmaceutical sciences or related life-sciences
    ·�������� Minimum 1-2 years experience as medical representative within a multinational pharmaceutical or nutritional company with proven track record of exceeding results
    ·�������� Very strong; presentation, communication and influencing skills
    ·�������� Good computer skills
    ·�������� Fluent in English
    We are offering a forward-thinking environment, with a professional culture and welcome applications from candidates with a similar mindset
    Candidates fitting the above mentioned requirements could be considered for an interview
    Please email copy of your current CV complete with recent photo no later than 7 days of this ad. to:

    Novartis Pharma Vacancy

    • Kalubia (Ref.1)
    • Qena (Ref.2)
    • Luxor (Ref.3)