Loading ...
Sorry, an error occurred while loading the content.

Re: [J-mtDNA] Haplogroup J1a* or J1c

Expand Messages
  • J. J. (Jim) Logan
    Doyle: Two factors immediately come to mind. I suspect both played a part in this case. First, there is no standard classification; it is still evolving and
    Message 1 of 26 , Dec 26, 2008
    View Source
    • 0 Attachment
      Doyle:

      Two factors immediately come to mind.  I suspect both played a part in this case.

      First, there is no standard classification; it is still evolving and the schemes that exist are not applied uniformly.  For example, the first scheme for classification of western European mtDNA, and that defined clades of haplogroup J was published in 2000 by a team of Richsrds, Macaulay, et al.  This scheme was based on actual sequencing of data at positions 16090 through 16365 except they specifically included 16069 for haplogroup J.  The then defined J1 based on a 16145 polymorphism and J1a based based on 16231.  But in 2004 when Palanichamy, et al, included HVR2 sequences in their studies, they found that this scheme was faulty and suggested that what had been J1a really was part of the J2 branch and that J1a should be retired as a nomenclature.  Most researchers since that time have followed this recommendation but the classification scheme itself still exists.  (I detailed more of this history in my paper in the Spring issue of the Journal of Genetic Genealogy.)  When Family Tree DNA reports on a full sequence test they are using later "standards".

      The second factor is the differences resulting is testing a continuous sequence and in sampling specific points in the sequence.  All of the Family Tree DNA tests for mtDNA are continuous through the range tested.  HVR1 is continuous for positions from 16001 through 16569, HVR2 is continuous from 1 through 574 and the Mega test is continuous from positions 1 through 16569.  I have not researched specifically what positions 23andMe check but they sample specific positions for both mtDNA and all the chromosomes.
      ====================
      J. J. (Jim) Logan
      Group Administrator, J-mtDNA, FxGS. and Logan DNA Projects
      Owner/Moderator, J-mtDNA and GenGen-NV Discussion Groups on Yahoo
      ===================================================================


      deking1945 wrote:

      23andme list my haplogroup as J1a* while my FGS from Ftdna list it J1c.
      Any explanations for this?

      Doyle King

    • jcmooreii
      But FTDNA must also use a classification scheme that would be outdated, because they list a couple of my exact matches on my HVR1 as J3, which I understand is
      Message 2 of 26 , Dec 27, 2008
      View Source
      • 0 Attachment
        But FTDNA must also use a classification scheme that would be
        outdated, because they list a couple of my exact matches on my HVR1 as
        J3, which I understand is outdated too. J Moore
      • restes@comcast.net
        I recall that 23andMe tests only 2000 mtdna locations as opposed to the full 15,569 at ftdna, plus they don t look at insertions and deletions, just at the
        Message 3 of 26 , Dec 27, 2008
        View Source
        • 0 Attachment
          I recall that 23andMe tests only 2000 mtdna locations as opposed to the full 15,569 at ftdna, plus they don't look at insertions and deletions, just at the "recipe".
           
          Roberta Estes
           
          -------------- Original message --------------
          From: "J. J. (Jim) Logan" <jjlnv@...>

          Doyle:

          Two factors immediately come to mind.  I suspect both played a part in this case.

          First, there is no standard classification; it is still evolving and the schemes that exist are not applied uniformly.  For example, the first scheme for classification of western European mtDNA, and that defined clades of haplogroup J was published in 2000 by a team of Richsrds, Macaulay, et al.  This scheme was based on actual sequencing of data at positions 16090 through 16365 except they specifically included 16069 for haplogroup J.  The then defined J1 based on a 16145 polymorphism and J1a based based on 16231.  But in 2004 when Palanichamy, et al, included HVR2 sequences in their studies, they found that this scheme was faulty and suggested that what had been J1a really was part of the J2 branch and that J1a should be retired as a nomenclature.  Most researchers since that time have followed this recommendation but the classification scheme i tself still exists.  (I detailed more of this history in my paper in the Spring issue of the Journal of Genetic Genealogy.)  When Family Tree DNA reports on a full sequence test they are using later "standards".

          The second factor is the differences resulting is testing a continuous sequence and in sampling specific points in the sequence.  All of the Family Tree DNA tests for mtDNA are continuous through the range tested.  HVR1 is continuous for positions from 16001 through 16569, HVR2 is continuous from 1 through 574 and the Mega test is continuous from positions 1 through 16569.  I have not researched specifically what positions 23andMe check but they sample specific positions for both mtDNA and all the chromosomes.

          ============ ========
          J. J. (Jim) Logan
          Group Administrator, J-mtDNA, FxGS. and Logan DNA Projects
          Owner/Moderator, J-mtDNA and GenGen-NV Discussion Groups on Yahoo
          ============ ========= ========= ========= ========= ========= ========= =


          deking1945 wrote:

          23andme list my haplogroup as J1a* while my FGS from Ftdna list it J1c.
          Any explanations for this?

          Doyle King

        • John Lloyd Scharf
          FTDNA s FGS is correct. Likely, 23andme is a prediction OR not up to date on the groupings. My haplogroup is designated as H3 and no present designated
          Message 4 of 26 , Dec 27, 2008
          View Source
          • 0 Attachment

            FTDNA's FGS is correct. Likely, 23andme is a prediction OR not up to date on the groupings.

            My haplogroup is designated as H3 and no present designated subclade includes my polymorphisms.
             
             HVR1 differences from CRS
            * 16519C
            * HVR2 differences from CRS
            * 263G
            * 315.1C
            * CR differences from CRS
            * 750G
            * 1438G
            * 4769G
            * 6776C
            * 7148C
            * 8860G
            * 15326G
            * 15519C

            I am yDNA J1 with my Halogroup due this week.

            I am mtDNA H3 because of my 6776C. I doubt that 23andme went by anything but the HVR1/HVR2.

            My subclade of H3 is not yet established as H3a, H3b, and H3c are not mine. Mine is under study by:

            Doron Behar MD, PhD Population Geneticist
            Doron Behar is their Chief mtDNA Scientist and member of the Scientific Advisory Board of FTDNA.
            Population geneticist and Senior Physician at the Department of Critical Care Medicine at the Rambam Medical Center, Haifa. Dr. Behar has pioneered scientific research on DNA variations of the mitochondrial DNA (mtDNA) and Y-chromosome in Jewish and Near Eastern populations. Dr. Behar is currently focusing on large scale mtDNA-based population genetic studies.

            I think there is no question that if there were a change, he would know it and there would be a notification of change. They do not need further testing to determine Haplogroup assignment after doing your FGS.

            I have no problems with publishing my mtDNA because I know all the issues with it and no one else but me has both my name and my mtDNA.

            If there is some question about anyone's results from www.FTDNA.com, I recommend you contact them. They are very willing to have discussions about haplogroups.

            I was originally designated J2 by Genebase and they tested my yDNA for the J1 as I suspected it would be. FTDNA thought I was close to J2, but they did not have high confidence, so they tested it for free. My cousin once removed was tested by Ancestry and told he was J2, even though he matched me on all 29 markers we had in common. They all use Dr. Mike Hammer's paper to predict yDNA haplotypes. He IS the on that "wrote the book" on it and that makes sense. Of course, he is also on the chief scientist on the board at FTDNA.

            My thought is if you check back on these folks, you will find their paperwork in the peer reviewed journals on mtDNA and yDNA. 23andme is likely tops in SNPs, but these are not their specialty and they do not have two databases, 0ne public and one private, that are larger than most states. Nor are they University based.


            --- In J-mtDNA@yahoogroups.com, "jcmooreii" <jcmooreii@...> wrote:
            >
            > But FTDNA must also use a classification scheme that would be
            > outdated, because they list a couple of my exact matches on my HVR1 as
            > J3, which I understand is outdated too. J Moore
            >

          • John Lloyd Scharf
            If you have had your FGS done, you might find this 2004 thesis on J1 helpful: http://class.csuhayward.edu/faculty/gmiller/3710/DNA_PDFS/mtDNA/mtHap_J_
            Message 5 of 26 , Dec 27, 2008
            View Source
            • 0 Attachment

              If you have had your FGS done, you might find this 2004 thesis on J1 helpful:

              http://class.csuhayward.edu/faculty/gmiller/3710/DNA_PDFS/mtDNA/mtHap_J_thesis.pdf

              If FTDNA had a J3, it would be listed on www.mitosearch.org, which they support as a public database.

              You cannot have an "exact match" with anyone based on HVR1. That can only be done with a FGS. I have over 5,000 matches at the HVR1 level. I have 290 at the HVR1/HVR2 level, of which 16 had been tested for FGS. I have NO matches on my FGS level of resolution.

              That means those 16, which "match" at lower levels of resolution, are NOT a match at the FGS level.  Unless you have a FGS, the term "exact match" certainly does not apply. I am not absolutely certain, but I think you could match at the FGS level and have very slight differences even though all your base pairs match.


              --- In J-mtDNA@yahoogroups.com, "jcmooreii" <jcmooreii@...> wrote:
              >
              > But FTDNA must also use a classification scheme that would be
              > outdated, because they list a couple of my exact matches on my HVR1 as
              > J3, which I understand is outdated too. J Moore
              >

            • John Lloyd Scharf
              You made a typo on that as it is 16,569 for the rCRS without any insertions or deletions. It may sound not so good for 23andme, but the FBI is only using 752
              Message 6 of 26 , Dec 27, 2008
              View Source
              • 0 Attachment
                You made a typo on that as it is 16,569 for the rCRS without any
                insertions or deletions.

                It may sound not so good for 23andme, but the FBI is only using 752 base
                pairs and making inferences of 3721 individuals in their database. When
                they do a DNA Identification for a "match," I have said it is unethical
                and useless. I have caught a lot of flack on a forensics group for that,
                but I am sticking with that.

                The FBI forensic report from Pre-Discovery is online and was done in a
                lab at Quantico. If the owner/moderator contacts me, I have no problem
                with uploading it to the group to check my research on it.


                --- In J-mtDNA@yahoogroups.com, restes@... wrote:
                >
                > I recall that 23andMe tests only 2000 mtdna locations as opposed to
                the full 15,569 at ftdna, plus they don't look at insertions and
                deletions, just at the "recipe".
                >
                > Roberta Estes
                >
                > -------------- Original message --------------
                > From: "J. J. (Jim) Logan" jjlnv@...
                > Doyle:
                >
                > Two factors immediately come to mind. I suspect both played a part in
                this case.
                >
                > First, there is no standard classification; it is still evolving and
                the schemes that exist are not applied uniformly. For example, the first
                scheme for classification of western European mtDNA, and that defined
                clades of haplogroup J was published in 2000 by a team of Richsrds,
                Macaulay, et al. This scheme was based on actual sequencing of data at
                positions 16090 through 16365 except they specifically included 16069
                for haplogroup J. The then defined J1 based on a 16145 polymorphism and
                J1a based based on 16231. But in 2004 when Palanichamy, et al, included
                HVR2 sequences in their studies, they found that this scheme was faulty
                and suggested that what had been J1a really was part of the J2 branch
                and that J1a should be retired as a nomenclature. Most researchers since
                that time have followed this recommendation but the classification
                scheme itself still exists. (I detailed more of this history in my paper
                in the Spring issue of the Journal of Genetic Genealogy.) When Family
                > Tree DNA reports on a full sequence test they are using later
                "standards".
                >
                > The second factor is the differences resulting is testing a continuous
                sequence and in sampling specific points in the sequence. All of the
                Family Tree DNA tests for mtDNA are continuous through the range tested.
                HVR1 is continuous for positions from 16001 through 16569, HVR2 is
                continuous from 1 through 574 and the Mega test is continuous from
                positions 1 through 16569. I have not researched specifically what
                positions 23andMe check but they sample specific positions for both
                mtDNA and all the chromosomes.
                >
                > ====================
                > J. J. (Jim) Logan
                > Group Administrator, J-mtDNA, FxGS. and Logan DNA Projects
                > Owner/Moderator, J-mtDNA and GenGen-NV Discussion Groups on Yahoo
                > ===================================================================
                >
                >
                > deking1945 wrote:
                > 23andme list my haplogroup as J1a* while my FGS from Ftdna list it
                J1c.
                > Any explanations for this?
                >
                > Doyle King
                >
              • J. J. (Jim) Logan
                John: If you are referring to the CODIS (Combined DNA Index System) when your refer to the FBI, that system looks as selected SNPs across a number of autosomal
                Message 7 of 26 , Dec 27, 2008
                View Source
                • 0 Attachment
                  John:

                  If you are referring to the CODIS (Combined DNA Index System) when your refer to the FBI, that system looks as selected SNPs across a number of autosomal chromosomes and looks at each member of the pair.  The power of discrimination comes from the fact each parent contributes one of each type of chromosome and that chromosome is a result of a mixing between pairs of chromosomes from each parent before they are passed to the next generation.  Thus the probability of any two persons having the same DNA pattern (except for identical twins) is extremely remote.
                  ====================
                  J. J. (Jim) Logan
                  Group Administrator, J-mtDNA, FxGS. and Logan DNA Projects
                  Owner/Moderator, J-mtDNA and GenGen-NV Discussion Groups on Yahoo
                  ===================================================================


                  John Lloyd Scharf wrote:


                  You made a typo on that as it is 16,569 for the rCRS without any
                  insertions or deletions.

                  It may sound not so good for 23andme, but the FBI is only using 752 base
                  pairs and making inferences of 3721 individuals in their database. When
                  they do a DNA Identification for a "match," I have said it is unethical
                  and useless. I have caught a lot of flack on a forensics group for that,
                  but I am sticking with that.

                  The FBI forensic report from Pre-Discovery is online and was done in a
                  lab at Quantico. If the owner/moderator contacts me, I have no problem
                  with uploading it to the group to check my research on it.

                  --- In J-mtDNA@yahoogroups .com, restes@... wrote:
                  >
                  > I recall that 23andMe tests only 2000 mtdna locations as opposed to
                  the full 15,569 at ftdna, plus they don't look at insertions and
                  deletions, just at the "recipe".
                  >
                  > Roberta Estes
                  >
                  > ------------ -- Original message ------------ --
                  > From: "J. J. (Jim) Logan" jjlnv@...
                  > Doyle:
                  >
                  > Two factors immediately come to mind. I suspect both played a part in
                  this case.
                  >
                  > First, there is no standard classification; it is still evolving and
                  the schemes that exist are not applied uniformly. For example, the first
                  scheme for classification of western European mtDNA, and that defined
                  clades of haplogroup J was published in 2000 by a team of Richsrds,
                  Macaulay, et al. This scheme was based on actual sequencing of data at
                  positions 16090 through 16365 except they specifically included 16069
                  for haplogroup J. The then defined J1 based on a 16145 polymorphism and
                  J1a based based on 16231. But in 2004 when Palanichamy, et al, included
                  HVR2 sequences in their studies, they found that this scheme was faulty
                  and suggested that what had been J1a really was part of the J2 branch
                  and that J1a should be retired as a nomenclature. Most researchers since
                  that time have followed this recommendation but the classification
                  scheme itself still exists. (I detailed more of this history in my paper
                  in the Spring issue of the Journal of Genetic Genealogy.) When Family
                  > Tree DNA reports on a full sequence test they are using later
                  "standards".
                  >
                  > The second factor is the differences resulting is testing a continuous
                  sequence and in sampling specific points in the sequence. All of the
                  Family Tree DNA tests for mtDNA are continuous through the range tested.
                  HVR1 is continuous for positions from 16001 through 16569, HVR2 is
                  continuous from 1 through 574 and the Mega test is continuous from
                  positions 1 through 16569. I have not researched specifically what
                  positions 23andMe check but they sample specific positions for both
                  mtDNA and all the chromosomes.
                  >
                  > ============ ========
                  > J. J. (Jim) Logan
                  > Group Administrator, J-mtDNA, FxGS. and Logan DNA Projects
                  > Owner/Moderator, J-mtDNA and GenGen-NV Discussion Groups on Yahoo
                  > ============ ========= ========= ========= ========= ========= ========= =
                  >
                  >
                  > deking1945 wrote:
                  > 23andme list my haplogroup as J1a* while my FGS from Ftdna list it
                  J1c.
                  > Any explanations for this?
                  >
                  > Doyle King
                  >

                • Joe Merante
                  John, I follow the forum although I am not an active participant; you always have extremely informative posts. I was impressed by the fact that you had over
                  Message 8 of 26 , Dec 27, 2008
                  View Source
                  • 0 Attachment
                     
                    John,
                    I follow the forum although I am not an active participant; you always have extremely informative posts.
                    I was impressed by the fact that you had over 5,000 matches at the HVR1 level.  I have taken the full sequence test.  I have had zero matches at any level since I received the results of my test over two years ago.  Is having no matches usual or unusual?  DNACousins and Jim Logan both classified me as J1c1. My mito search ID is QXGKN.
                    Thanks
                    Joe Merante




                    To: J-mtDNA@yahoogroups.com
                    From: johnlloydscharf@...
                    Date: Sun, 28 Dec 2008 03:10:41 +0000
                    Subject: [J-mtDNA] Re: Haplogroup J1a* or J1c


                    If you have had your FGS done, you might find this 2004 thesis on J1 helpful:
                    http://class. csuhayward. edu/faculty/ gmiller/3710/ DNA_PDFS/ mtDNA/mtHap_ J_thesis. pdf
                    If FTDNA had a J3, it would be listed on www.mitosearch. org, which they support as a public database.
                    You cannot have an "exact match" with anyone based on HVR1. That can only be done with a FGS. I have over 5,000 matches at the HVR1 level. I have 290 at the HVR1/HVR2 level, of which 16 had been tested for FGS. I have NO matches on my FGS level of resolution.
                    That means those 16, which "match" at lower levels of resolution, are NOT a match at the FGS level.  Unless you have a FGS, the term "exact match" certainly does not apply. I am not absolutely certain, but I think you could match at the FGS level and have very slight differences even though all your base pairs match.

                    --- In J-mtDNA@yahoogroups .com, "jcmooreii" <jcmooreii@.. .> wrote:
                    >
                    > But FTDNA must also use a classification scheme that would be
                    > outdated, because they list a couple of my exact matches on my HVR1 as
                    > J3, which I understand is outdated too. J Moore
                    >


                  • John Lloyd Scharf
                    It should be plain from what I wrote that I am absolutely not refering to the CODIS database. They only use 13 markers for that, compared to the 16 used in
                    Message 9 of 26 , Dec 28, 2008
                    View Source
                    • 0 Attachment

                       

                       

                      It should be plain from what I wrote that I am absolutely not refering to the CODIS database. They only use 13 markers for that, compared to the 16 used in some states. An attempt was made, recently, to match on only five and the jury said "Not Guilty." For that, they have a database of over six million. Matches have been found between individuals in Arizona at 10 loci. In Maryland and Illinois, there have been matches at 13 of 13. The FBI defense to that is the Birthday Paradox.

                      No, the FBI testing for MITOCHONDRIAL DNA, according to the report is as I said; only 752 base pairs and that database they had, at less than six months ago, only included 3711 other individuals. They were making inferences from their own database about African Americans, Caucasians, and Hispanics. Even with that small database, they claimed 25 others matched Casey Anthony. With the very slim information they had, she could be T2.

                      On the suspect sample hair on the shovel was rCRS for the HVR1 and 263/315.1 for HVR2. Given the fact that my own 16,519, which is very common in the H haplogroup, cannot show up in this test, I would be a match to it, according to their very low resolution testing. I will try to upload the three pages of that part of the report so it is more understandable exactly what they said - to the pictures section. The full forensic report is too large for Yahoo to accept in groups.

                      What people should get from this, if nothing else, is that those who test with FTDNA should be very proud of the results, even if they do not have a FGS test.

                      With respect to your assertion that no two people can remotely have the same DNA pattern, remember that we came from a bottleneck of only 2,000 people 70,000 years ago and share over 99.7% of the same DNA. When they do these tests, they are only checking a miniscule part of three billion base pairs - less than 5200 base pairs. So, comparing them with identical twins is not exactly useful for a few reasons.

                      Other than what was mentioned before, there are some interesting issues about twins themselves. My mother and her sister were mirror twins. They also, as is common among identical twins, had non-identical fingerprints. My mother was left handed and her sister right handed, even though there was only one placenta.

                      Recently, I was watching one of the Discovery channels and they had twins, both with a genetic marker in common for a disease. One had the disease and the other did not express it, though they are genetic twins.

                      The contention now is that even identical twins do not have identical DNA, even though they match at the level of resolution (24 and 30 loci instead of the FBI's 13) of autosomal testing higher than the CODIS.

                      Keep in mind, less than 20 humans in the world have had a full genome sequencing of their nuclear DNA. We do not know what happens when twins split because they have not been tested and compared yet.

                      In living humans, there are changes in mitochondrial DNA. It is only a few mitochondria among billions of reproductions,  but it happens. Toxins and radiation are sources of those changes and account for type II diabetes among Vets.

                      I am not an authority on DNA by any means, but I keep on having new tests done. My father and his two brothers were orphans adopted by separate families. I used to be concerned about that until my cousin once removed by one of those brothers produced a match at 29 markers by another commercial service on yDNA. I have had 85 markers tested in that area for my research. There is a 41 marker haplotype I have created that has many matches. I use it to narrow down geographic and ethnic origins.

                      The FGS testing was for the same purpose. H3 is very common, but I think I have have narrowed it down to Scotland with my FGS as opposed to the European hordes of them. Three subclades of H3 are on their way to being designated, but I am not among them either. When you are looking for clues, being unique is a bit frustrating.

                      So, no, I am not J1 mtDNA. I monitor this group because it is one of the few for mtDNA and there are no changes that do not have common applications. I see that some are frustrated as well, but the databases for mtDNA are growing in size and resolution.

                      I know that some in this group are frustrated because of how technical it seems. Think of it like trying to get a picture of your ancestors. Long ago, they only used a silloette (sp). Then they had black and white images on plates. Then they had black and white images on film. Now they have 16 megabyte pictures in digital files.

                      Still, a healthy eye can see a resolution that can be compared with a 130 megabyte image. Our brains just fill in the blanks at lower resolutions. The interesting fact about vision is that, according to studies, women are more apt at facial recognition, along with the fact that they can listen to more than one conversation at once and monitor simultaneous operations. It has something to do with being undifferientiated and using both sides of the brain. Of course, there are exceptions, but I think men do well, for having "half their brain tied behind their backs."

                      In genealogy, perhaps that is why they do not get as frustrated with family trees as I do. Most in the forensic labs are women, but they need to start looking at criminal justice and security seriously as careers.

                      For me, numbers are more comforting. I hate filling in the blanks. If I start tying that side of my mind down, I have nothing left. So, take pity on the cripple and try to overlook my dependence on numbers.

                      _______________________________________________________________________________________

                      John:

                      If you are referring to the CODIS (Combined DNA Index System) when your refer to the FBI, that system looks as selected SNPs across a number of autosomal chromosomes and looks at each member of the pair.  The power of discrimination comes from the fact each parent contributes one of each type of chromosome and that chromosome is a result of a mixing between pairs of chromosomes from each parent before they are passed to the next generation.  Thus the probability of any two persons having the same DNA pattern (except for identical twins) is extremely remote.

                      ====================
                      J. J. (Jim) Logan
                      Group Administrator, J-mtDNA, FxGS. and Logan DNA Projects
                      Owner/Moderator, J-mtDNA and GenGen-NV Discussion Groups on Yahoo
                      ===================================================================
                    • Moore
                      Nevertheless, I do have 2 people, who ARE matches to me at the HVR1 level, who are listed by FTDNA as J3. Mr Logan has kindly given me a reference for the
                      Message 10 of 26 , Dec 28, 2008
                      View Source
                      • 0 Attachment
                        Nevertheless, I do have 2 people, who ARE matches to me at the HVR1 level, who are listed by FTDNA as "J3. Mr Logan has kindly given me a reference for the paper with the J3 classification, which definitely IS an old classification. Thus by uing the J3 for someone, they evidently ARE using an older scheme to classify people, or there is a typo. Plus, if these people in question do not belong to mitosearch, you may not be able to see there results.
                        Finally, I have a deep background in biological sciences and am not much impressed by "who wrote the book". Todays cutting edge can easily become old news tomorrow. J Moore

                      • Moore
                        Here is the copy of the email from FTDNA to me re J3:   From: Darren Marin [mailto:darren@familytreedna.com] Sent: Wednesday, September 24, 2008 6:24 PM To:
                        Message 11 of 26 , Dec 28, 2008
                        View Source
                        • 0 Attachment
                          Here is the copy of the email from FTDNA to me re J3:
                           
                          "From: Darren Marin [mailto:darren@...]
                          Sent: Wednesday, September 24, 2008 6:24 PM
                          To: Moore, Jack (BHE)
                          Subject: RE: mito group J3

                          Dear J,

                           

                          Thank you for your email.   This is a very uncommon haplogroup in the database because it can only be identified by the Full Sequence test.  Currently scientists are able to identify this branch genetically but have not yet associated it with a specific ancestral population or geographic location.  So far the majority of the test takers that arte J3 are coming from the British Isles with a concentration in Ireland, however this may not be a true reflection of the earth’s population, so we don’t want to read too much into it at this time. 

                           

                          Feel free to contact me if you have any questions or need additional assistance.  Have a great day.

                           

                          Darren Marin

                          Family Tree DNA

                          713.868.1438

                          http://www.FamilyTreeDNA.com

                          "History Unearthed Daily"

                           

                           

                          There are people who are classified by FTDNA as J3. Now, here is the reference from Mr Logan:

                           

                           

                           "On Fri, 10/24/08, J. J. (Jim) Logan <JJLNV@...> wrote:

                          From: J. J. (Jim) Logan <JJLNV@...>
                          Subject: Re: [J-mtDNA] Re: New mtdna haplogroup J results.
                          To: "Moore" <jcmooreii@...>
                          Date: Friday, October 24, 2008, 6:44 PM

                          No, the messages must have passed in the mail.  I have now seen it and and the message to which I am replying and thus I now understand the context of your question. 

                          I have done some research and found a 2002 paper by Hernstedt et al (http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=447592) that claimed to find a small subcluster that they designated J3.  I also found a 2004 paper by Coble et al that included references to J3 and J4 subclusters.  (This paper is available only by paid subscription.)   Both papers were in the early days of sequencing and before development of the classification scheme that FTDNA is currently using for their HVR1 classifications.  I did not find any current usage of these designations.  Furthremore, three test results that Coble classified as J3 are now carried as J1c in GenBank, the international data base on DNA sequences maintain by the National Institutes of Health.

                          By the way, I do not find kit N16336 in the J-mtDNA project.
                          ====
                          J. J. (Jim) Logan
                          Group Administrator, J-mtDNA, FxGS, and Logan DNA Projects
                          Owner/Moderator, J-mtDNA discussion group on Yahoo
                          FxGS SIG Leader, Surname Projects and Genetic Genealogy"
                           
                          The studies which lists J3 are somewhat "old". 
                           
                          Slainte, 
                          J Moore 
                          

                        • John Lloyd Scharf
                          I do not know what they may know in many areas. I can only say what I can see by your QXGKN account. And the J1C1, though you listed yourself as J1b1. There
                          Message 12 of 26 , Dec 29, 2008
                          View Source
                          • 0 Attachment

                            I do not know what they may know in many areas.  I can only say what I can see by your QXGKN account. And the J1C1, though you listed yourself as J1b1. There is only one J1c1 in the database and he is from Spain, while the J1b1 has as many in that subclade, at www.mitosearch.org , as my H3. Most of the database is from the US and, therefore, tilted toward Scots-Irish.

                            You have two deletions in the HVR2, which by itself would be rare. J1c1 is rare as there is only one in the database listed as such. Given that, I cannot recommend you publish your FGS without some professional genetic consultation.

                            My SWAG, or Scientific Wild Atrophied Guess, is the following possibilities just to begin with:

                            It could be nothing or it could be aging. It could be you had an elderly mother at birth in your lineage or you should have stopped chewing tobacco months before you gave up a sample. Not that it is related here at all, but some Vietnam Vets exposed to Agent Orange had changes in their mito. A check of muscle or blood mito could give different results. It is rare, but possible, as are the rest of this SWAG.

                            You may want to confirm your results with a mito relative. On the other hand, rare birds are more easily traced to a geographic/ethnic origin, in my opinion. Given so few of us have tested for the FGS, the more who take that option, the more resolution we get, even if we have a near miss.

                            Our DNA is compared with an H2 with some rare polymorhisms of an individual at Cambridge, rather than L3 out of Africa. That is the Cambridge in the Revised Cambridge Reference Sequence (rCRS). I have seen only one study that used L3.  The original CRS had mistakes in sequencing and contamination from a cow, so they had to resequence it. The individual involved still had seven rare polymorphisms, meaning she was not actually representative. An individual could have all seven of those and still be H2, from what I understand.

                            Just from the large numbers of polymorphisms you show in your HVR1/HVR2, you are very far from the H2, which a J1c1 would certainly be. I do not have a chart for J1 or your differences from the rCRS outside of the HVR1/HVR2, so I could not even begin to make inferences about your subclade or the areas it is likely from.

                            If we get into SWAG again, I would say your deep ancestry is from an Arab influx into the Iberian Peninsula at least 600 years ago. You just do not have enough information, yet, and you should hold SWAG on the same level as someone doing a read with Tarot cards, shuffled by a Scots-Irish descendent, because of the influence of the US on ordering mtDNA results.


                            --- In J-mtDNA@yahoogroups.com, Joe Merante <merantej@...> wrote:
                            >
                            >
                            >
                            > John,
                            > I follow the forum although I am not an active participant; you always have extremely informative posts.
                            > I was impressed by the fact that you had over 5,000 matches at the HVR1 level. I have taken the full sequence test. I have had zero matches at any level since I received the results of my test over two years ago. Is having no matches usual or unusual? DNACousins and Jim Logan both classified me as J1c1. My mito search ID is QXGKN.
                            > Thanks
                            > Joe Merante
                            >
                            >
                            >
                            > To: J-mtDNA@...: johnlloydscharf@...: Sun, 28 Dec 2008 03:10:41 +0000Subject: [J-mtDNA] Re: Haplogroup J1a* or J1c
                            >
                            >
                            >
                            >
                            > If you have had your FGS done, you might find this 2004 thesis on J1 helpful:
                            > http://class.csuhayward.edu/faculty/gmiller/3710/DNA_PDFS/mtDNA/mtHap_J_thesis.pdf
                            > If FTDNA had a J3, it would be listed on www.mitosearch.org, which they support as a public database.
                            > You cannot have an "exact match" with anyone based on HVR1. That can only be done with a FGS. I have over 5,000 matches at the HVR1 level. I have 290 at the HVR1/HVR2 level, of which 16 had been tested for FGS. I have NO matches on my FGS level of resolution.
                            > That means those 16, which "match" at lower levels of resolution, are NOT a match at the FGS level. Unless you have a FGS, the term "exact match" certainly does not apply. I am not absolutely certain, but I think you could match at the FGS level and have very slight differences even though all your base pairs match.
                            > --- In J-mtDNA@yahoogroups.com, "jcmooreii" jcmooreii@ wrote:>> But FTDNA must also use a classification scheme that would be > outdated, because they list a couple of my exact matches on my HVR1 as > J3, which I understand is outdated too. J Moore>
                            >

                          • Joe Merante
                            John, Thank you for your thoughtful review. Except for the tobacco, you seem to be hitting the right direction. Elderly mothers were the norm for my maternal
                            Message 13 of 26 , Dec 31, 2008
                            View Source
                            • 0 Attachment
                              John,
                              Thank you for your thoughtful review.  Except for the tobacco, you seem to be hitting the right direction.  Elderly mothers were the norm for my maternal line for at leat three generation.  And, although my oldest maternal line records (mid 1700s) places this line in Italy, it is family lore that they came from Spain.
                              I will ask my brother to test to compare.  Is HVR 1 sufficient, or should we do HVR 2 also.
                              Again Thanks.
                              Joe Merante




                              To: J-mtDNA@yahoogroups.com
                              From: johnlloydscharf@...
                              Date: Mon, 29 Dec 2008 22:48:43 +0000
                              Subject: [J-mtDNA] Re: Haplogroup J1a* or J1c


                              I do not know what they may know in many areas.  I can only say what I can see by your QXGKN account. And the J1C1, though you listed yourself as J1b1. There is only one J1c1 in the database and he is from Spain, while the J1b1 has as many in that subclade, at www.mitosearch. org , as my H3. Most of the database is from the US and, therefore, tilted toward Scots-Irish.
                              You have two deletions in the HVR2, which by itself would be rare. J1c1 is rare as there is only one in the database listed as such. Given that, I cannot recommend you publish your FGS without some professional genetic consultation.
                              My SWAG, or Scientific Wild Atrophied Guess, is the following possibilities just to begin with:
                              It could be nothing or it could be aging. It could be you had an elderly mother at birth in your lineage or you should have stopped chewing tobacco months before you gave up a sample. Not that it is related here at all, but some Vietnam Vets exposed to Agent Orange had changes in their mito. A check of muscle or blood mito could give different results. It is rare, but possible, as are the rest of this SWAG.
                              You may want to confirm your results with a mito relative. On the other hand, rare birds are more easily traced to a geographic/ethnic origin, in my opinion. Given so few of us have tested for the FGS, the more who take that option, the more resolution we get, even if we have a near miss.
                              Our DNA is compared with an H2 with some rare polymorhisms of an individual at Cambridge, rather than L3 out of Africa. That is the Cambridge in the Revised Cambridge Reference Sequence (rCRS). I have seen only one study that used L3.  The original CRS had mistakes in sequencing and contamination from a cow, so they had to resequence it. The individual involved still had seven rare polymorphisms, meaning she was not actually representative. An individual could have all seven of those and still be H2, from what I understand.
                              Just from the large numbers of polymorphisms you show in your HVR1/HVR2, you are very far from the H2, which a J1c1 would certainly be. I do not have a chart for J1 or your differences from the rCRS outside of the HVR1/HVR2, so I could not even begin to make inferences about your subclade or the areas it is likely from.
                              If we get into SWAG again, I would say your deep ancestry is from an Arab influx into the Iberian Peninsula at least 600 years ago. You just do not have enough information, yet, and you should hold SWAG on the same level as someone doing a read with Tarot cards, shuffled by a Scots-Irish descendent, because of the influence of the US on ordering mtDNA results.

                              --- In J-mtDNA@yahoogroups .com, Joe Merante <merantej@...> wrote:
                              >
                              >
                              >
                              > John,
                              > I follow the forum although I am not an active participant; you always have extremely informative posts.
                              > I was impressed by the fact that you had over 5,000 matches at the HVR1 level. I have taken the full sequence test. I have had zero matches at any level since I received the results of my test over two years ago. Is having no matches usual or unusual? DNACousins and Jim Logan both classified me as J1c1. My mito search ID is QXGKN.
                              > Thanks
                              > Joe Merante
                              >
                              >
                              >
                              > To: J-mtDNA@...: johnlloydscharf@ ...: Sun, 28 Dec 2008 03:10:41 +0000Subject: [J-mtDNA] Re: Haplogroup J1a* or J1c
                              >
                              >
                              >
                              >
                              > If you have had your FGS done, you might find this 2004 thesis on J1 helpful:
                              > http://class. csuhayward. edu/faculty/ gmiller/3710/ DNA_PDFS/ mtDNA/mtHap_ J_thesis. pdf
                              > If FTDNA had a J3, it would be listed on www.mitosearch. org, which they support as a public database.
                              > You cannot have an "exact match" with anyone based on HVR1. That can only be done with a FGS. I have over 5,000 matches at the HVR1 level. I have 290 at the HVR1/HVR2 level, of which 16 had been tested for FGS. I have NO matches on my FGS level of resolution.
                              > That means those 16, which "match" at lower levels of resolution, are NOT a match at the FGS level. Unless you have a FGS, the term "exact match" certainly does not apply. I am not absolutely certain, but I think you could match at the FGS level and have very slight differences even though all your base pairs match.
                              > --- In J-mtDNA@yahoogroups .com, "jcmooreii" jcmooreii@ wrote:>> But FTDNA must also use a classification scheme that would be > outdated, because they list a couple of my exact matches on my HVR1 as > J3, which I understand is outdated too. J Moore>
                              >


                            • Hannah Lloyd
                              What s an elderly mother? ... Hannah Lloyd BGS CSAC Dr. Lewis Weber & Associates Tanglewood West Office Building Suite 348 3959 Electric Road Roanoke, VA
                              Message 14 of 26 , Dec 31, 2008
                              View Source
                              • 0 Attachment
                                What's an elderly mother? 

                                On Dec 31, 2008, at 7:24 AM, Joe Merante wrote:

                                John,
                                Thank you for your thoughtful review.  Except for the tobacco, you seem to be hitting the right direction.  Elderly mothers were the norm for my maternal line for at leat three generation.  And, although my oldest maternal line records (mid 1700s) places this line in Italy, it is family lore that they came from Spain.
                                I will ask my brother to test to compare.  Is HVR 1 sufficient, or should we do HVR 2 also.
                                Again Thanks.
                                Joe Merante




                                To: J-mtDNA@yahoogroups .com
                                From: johnlloydscharf@ yahoo.com
                                Date: Mon, 29 Dec 2008 22:48:43 +0000
                                Subject: [J-mtDNA] Re: Haplogroup J1a* or J1c


                                I do not know what they may know in many areas.  I can only say what I can see by your QXGKN account. And the J1C1, though you listed yourself as J1b1. There is only one J1c1 in the database and he is from Spain, while the J1b1 has as many in that subclade, at www.mitosearch. org , as my H3. Most of the database is from the US and, therefore, tilted toward Scots-Irish. 
                                You have two deletions in the HVR2, which by itself would be rare. J1c1 is rare as there is only one in the database listed as such. Given that, I cannot recommend you publish your FGS without some professional genetic consultation. 
                                My SWAG, or Scientific Wild Atrophied Guess, is the following possibilities just to begin with:
                                It could be nothing or it could be aging. It could be you had an elderly mother at birth in your lineage or you should have stopped chewing tobacco months before you gave up a sample. Not that it is related here at all, but some Vietnam Vets exposed to Agent Orange had changes in their mito. A check of muscle or blood mito could give different results. It is rare, but possible, as are the rest of this SWAG. 
                                You may want to confirm your results with a mito relative. On the other hand, rare birds are more easily traced to a geographic/ethnic origin, in my opinion. Given so few of us have tested for the FGS, the more who take that option, the more resolution we get, even if we have a near miss. 
                                Our DNA is compared with an H2 with some rare polymorhisms of an individual at Cambridge, rather than L3 out of Africa. That is the Cambridge in the Revised Cambridge Reference Sequence (rCRS). I have seen only one study that used L3.  The original CRS had mistakes in sequencing and contamination from a cow, so they had to resequence it. The individual involved still had seven rare polymorphisms, meaning she was not actually representative. An individual could have all seven of those and still be H2, from what I understand. 
                                Just from the large numbers of polymorphisms you show in your HVR1/HVR2, you are very far from the H2, which a J1c1 would certainly be. I do not have a chart for J1 or your differences from the rCRS outside of the HVR1/HVR2, so I could not even begin to make inferences about your subclade or the areas it is likely from. 
                                If we get into SWAG again, I would say your deep ancestry is from an Arab influx into the Iberian Peninsula at least 600 years ago. You just do not have enough information, yet, and you should hold SWAG on the same level as someone doing a read with Tarot cards, shuffled by a Scots-Irish descendent, because of the influence of the US on ordering mtDNA results. 

                                --- In J-mtDNA@yahoogroups .com, Joe Merante <merantej@...> wrote:
                                >
                                > 
                                > 
                                > John,
                                > I follow the forum although I am not an active participant; you always have extremely informative posts.
                                > I was impressed by the fact that you had over 5,000 matches at the HVR1 level. I have taken the full sequence test. I have had zero matches at any level since I received the results of my test over two years ago. Is having no matches usual or unusual? DNACousins and Jim Logan both classified me as J1c1. My mito search ID is QXGKN.
                                > Thanks
                                > Joe Merante
                                > 
                                > 
                                > 
                                > To: J-mtDNA@...: johnlloydscharf@ ...: Sun, 28 Dec 2008 03:10:41 +0000Subject: [J-mtDNA] Re: Haplogroup J1a* or J1c
                                > 
                                > 
                                > 
                                > 
                                > If you have had your FGS done, you might find this 2004 thesis on J1 helpful:
                                > http://class. csuhayward. edu/faculty/ gmiller/3710/ DNA_PDFS/ mtDNA/mtHap_ J_thesis. pdf
                                > If FTDNA had a J3, it would be listed on www.mitosearch. org, which they support as a public database. 
                                > You cannot have an "exact match" with anyone based on HVR1. That can only be done with a FGS. I have over 5,000 matches at the HVR1 level. I have 290 at the HVR1/HVR2 level, of which 16 had been tested for FGS. I have NO matches on my FGS level of resolution.
                                > That means those 16, which "match" at lower levels of resolution, are NOT a match at the FGS level. Unless you have a FGS, the term "exact match" certainly does not apply. I am not absolutely certain, but I think you could match at the FGS level and have very slight differences even though all your base pairs match. 
                                > --- In J-mtDNA@yahoogroups .com, "jcmooreii" jcmooreii@ wrote:>> But FTDNA must also use a classification scheme that would be > outdated, because they list a couple of my exact matches on my HVR1 as > J3, which I understand is outdated too. J Moore>
                                >





                                Hannah Lloyd
                                  
                                BGS CSAC
                                Dr. Lewis Weber & Associates
                                Tanglewood West Office Building
                                Suite 348
                                3959 Electric Road
                                Roanoke, VA 24018
                                work: 540 815-4214
                                fax: 540 772-9119
                                Addiction Recovery Resources for Professionals
                                          
                                The information contained in this email and subsequent attachments may be privileged, confidential and protected from disclosure.  This transmission is intended for the sole use of the individual and entity to whom it is addressed.  If you are not the intended recipient, any dissemination, distribution or copying is strictly prohibited. If you have received this message in error, please email the sender at the above email address.




                              • Joe Merante
                                Over 35. And, i really should have said older as opposed to elderly . To: J-mtDNA@yahoogroups.comFrom: hannahlloyd@mac.comDate: Wed, 31 Dec 2008 12:48:46
                                Message 15 of 26 , Dec 31, 2008
                                View Source
                                • 0 Attachment
                                   
                                  Over 35.  And, i really should have said "older" as opposed to "elderly".


                                  To: J-mtDNA@yahoogroups.com
                                  From: hannahlloyd@...
                                  Date: Wed, 31 Dec 2008 12:48:46 -0500
                                  Subject: [J-mtDNA] elderly?


                                  What's an elderly mother? 

                                  On Dec 31, 2008, at 7:24 AM, Joe Merante wrote:

                                  John,
                                  Thank you for your thoughtful review.  Except for the tobacco, you seem to be hitting the right direction.  Elderly mothers were the norm for my maternal line for at leat three generation.  And, although my oldest maternal line records (mid 1700s) places this line in Italy, it is family lore that they came from Spain.
                                  I will ask my brother to test to compare.  Is HVR 1 sufficient, or should we do HVR 2 also.
                                  Again Thanks.
                                  Joe Merante





                                  To: J-mtDNA@yahoogroups .com
                                  From: johnlloydscharf@ yahoo.com
                                  Date: Mon, 29 Dec 2008 22:48:43 +0000
                                  Subject: [J-mtDNA] Re: Haplogroup J1a* or J1c


                                  I do not know what they may know in many areas.  I can only say what I can see by your QXGKN account. And the J1C1, though you listed yourself as J1b1. There is only one J1c1 in the database and he is from Spain, while the J1b1 has as many in that subclade, at www.mitosearch. org , as my H3. Most of the database is from the US and, therefore, tilted toward Scots-Irish. 
                                  You have two deletions in the HVR2, which by itself would be rare. J1c1 is rare as there is only one in the database listed as such. Given that, I cannot recommend you publish your FGS without some professional genetic consultation. 
                                  My SWAG, or Scientific Wild Atrophied Guess, is the following possibilities just to begin with:
                                  It could be nothing or it could be aging. It could be you had an elderly mother at birth in your lineage or you should have stopped chewing tobacco months before you gave up a sample. Not that it is related here at all, but some Vietnam Vets exposed to Agent Orange had changes in their mito. A check of muscle or blood mito could give different results. It is rare, but possible, as are the rest of this SWAG. 
                                  You may want to confirm your results with a mito relative. On the other hand, rare birds are more easily traced to a geographic/ethnic origin, in my opinion. Given so few of us have tested for the FGS, the more who take that option, the more resolution we get, even if we have a near miss. 
                                  Our DNA is compared with an H2 with some rare polymorhisms of an individual at Cambridge, rather than L3 out of Africa. That is the Cambridge in the Revised Cambridge Reference Sequence (rCRS). I have seen only one study that used L3.  The original CRS had mistakes in sequencing and contamination from a cow, so they had to resequence it. The individual involved still had seven rare polymorphisms, meaning she was not actually representative. An individual could have all seven of those and still be H2, from what I understand. 
                                  Just from the large numbers of polymorphisms you show in your HVR1/HVR2, you are very far from the H2, which a J1c1 would certainly be. I do not have a chart for J1 or your differences from the rCRS outside of the HVR1/HVR2, so I could not even begin to make inferences about your subclade or the areas it is likely from. 
                                  If we get into SWAG again, I would say your deep ancestry is from an Arab influx into the Iberian Peninsula at least 600 years ago. You just do not have enough information, yet, and you should hold SWAG on the same level as someone doing a read with Tarot cards, shuffled by a Scots-Irish descendent, because of the influence of the US on ordering mtDNA results. 

                                  --- In J-mtDNA@yahoogroups .com, Joe Merante <merantej@... > wrote:
                                  >
                                  > 
                                  > 
                                  > John,
                                  > I follow the forum although I am not an active participant; you always have extremely informative posts.
                                  > I was impressed by the fact that you had over 5,000 matches at the HVR1 level. I have taken the full sequence test. I have had zero matches at any level since I received the results of my test over two years ago. Is having no matches usual or unusual? DNACousins and Jim Logan both classified me as J1c1. My mito search ID is QXGKN.
                                  > Thanks
                                  > Joe Merante
                                  > 
                                  > 
                                  > 
                                  > To: J-mtDNA@...: johnlloydscharf@ ...: Sun, 28 Dec 2008 03:10:41 +0000Subject: [J-mtDNA] Re: Haplogroup J1a* or J1c
                                  > 
                                  > 
                                  > 
                                  > 
                                  > If you have had your FGS done, you might find this 2004 thesis on J1 helpful:
                                  > http://class. csuhayward. edu/faculty/ gmiller/3710/ DNA_PDFS/ mtDNA/mtHap_ J_thesis. pdf
                                  > If FTDNA had a J3, it would be listed on www.mitosearch. org, which they support as a public database. 
                                  > You cannot have an "exact match" with anyone based on HVR1. That can only be done with a FGS. I have over 5,000 matches at the HVR1 level. I have 290 at the HVR1/HVR2 level, of which 16 had been tested for FGS. I have NO matches on my FGS level of resolution.
                                  > That means those 16, which "match" at lower levels of resolution, are NOT a match at the FGS level. Unless you have a FGS, the term "exact match" certainly does not apply. I am not absolutely certain, but I think you could match at the FGS level and have very slight differences even though all your base pairs match. 
                                  > --- In J-mtDNA@yahoogroups .com, "jcmooreii" jcmooreii@ wrote:>> But FTDNA must also use a classification scheme that would be > outdated, because they list a couple of my exact matches on my HVR1 as > J3, which I understand is outdated too. J Moore>
                                  >






                                  Hannah Lloyd
                                    
                                  BGS CSAC
                                  Dr. Lewis Weber & Associates
                                  Tanglewood West Office Building
                                  Suite 348
                                  3959 Electric Road
                                  Roanoke, VA 24018
                                  work: 540 815-4214
                                  fax: 540 772-9119
                                  Addiction Recovery Resources for Professionals
                                            
                                  The information contained in this email and subsequent attachments may be privileged, confidential and protected from disclosure.  This transmission is intended for the sole use of the individual and entity to whom it is addressed.  If you are not the intended recipient, any dissemination, distribution or copying is strictly prohibited. If you have received this message in error, please email the sender at the above email address.





                                • Judy Houck
                                  I had my third and last child at age 39. The first two were born in my early 20 s. This third one was a real suprise. I don t know if there were any DNA
                                  Message 16 of 26 , Dec 31, 2008
                                  View Source
                                  • 0 Attachment
                                    I had my third and last child at age 39.  The first two were born in my early 20's.
                                    This third one was a real suprise.  I don't know if there were any DNA changes between the first two and the last.  I did take the amniocentyesis (? spelling) test
                                    and that only checks for Down syndrome which was negative.  He has basically been normal since birth.  Scores high on his school testing.
                                     
                                    Judy Carter



                                    To: j-mtdna@yahoogroups.com
                                    From: merantej@...
                                    Date: Wed, 31 Dec 2008 07:24:14 -0500
                                    Subject: RE: [J-mtDNA] Re: Haplogroup J1a* or J1c


                                    John,
                                    Thank you for your thoughtful review.  Except for the tobacco, you seem to be hitting the right direction.  Elderly mothers were the norm for my maternal line for at leat three generation.  And, although my oldest maternal line records (mid 1700s) places this line in Italy, it is family lore that they came from Spain.
                                    I will ask my brother to test to compare.  Is HVR 1 sufficient, or should we do HVR 2 also.
                                    Again Thanks.
                                    Joe Merante




                                    To: J-mtDNA@yahoogroups .com
                                    From: johnlloydscharf@ yahoo.com
                                    Date: Mon, 29 Dec 2008 22:48:43 +0000
                                    Subject: [J-mtDNA] Re: Haplogroup J1a* or J1c


                                    I do not know what they may know in many areas.  I can only say what I can see by your QXGKN account. And the J1C1, though you listed yourself as J1b1. There is only one J1c1 in the database and he is from Spain, while the J1b1 has as many in that subclade, at www.mitosearch. org , as my H3. Most of the database is from the US and, therefore, tilted toward Scots-Irish.
                                    You have two deletions in the HVR2, which by itself would be rare. J1c1 is rare as there is only one in the database listed as such. Given that, I cannot recommend you publish your FGS without some professional genetic consultation.
                                    My SWAG, or Scientific Wild Atrophied Guess, is the following possibilities just to begin with:
                                    It could be nothing or it could be aging. It could be you had an elderly mother at birth in your lineage or you should have stopped chewing tobacco months before you gave up a sample. Not that it is related here at all, but some Vietnam Vets exposed to Agent Orange had changes in their mito. A check of muscle or blood mito could give different results. It is rare, but possible, as are the rest of this SWAG.
                                    You may want to confirm your results with a mito relative. On the other hand, rare birds are more easily traced to a geographic/ethnic origin, in my opinion. Given so few of us have tested for the FGS, the more who take that option, the more resolution we get, even if we have a near miss.
                                    Our DNA is compared with an H2 with some rare polymorhisms of an individual at Cambridge, rather than L3 out of Africa. That is the Cambridge in the Revised Cambridge Reference Sequence (rCRS). I have seen only one study that used L3.  The original CRS had mistakes in sequencing and contamination from a cow, so they had to resequence it. The individual involved still had seven rare polymorphisms, meaning she was not actually representative. An individual could have all seven of those and still be H2, from what I understand.
                                    Just from the large numbers of polymorphisms you show in your HVR1/HVR2, you are very far from the H2, which a J1c1 would certainly be. I do not have a chart for J1 or your differences from the rCRS outside of the HVR1/HVR2, so I could not even begin to make inferences about your subclade or the areas it is likely from.
                                    If we get into SWAG again, I would say your deep ancestry is from an Arab influx into the Iberian Peninsula at least 600 years ago. You just do not have enough information, yet, and you should hold SWAG on the same level as someone doing a read with Tarot cards, shuffled by a Scots-Irish descendent, because of the influence of the US on ordering mtDNA results.

                                    --- In J-mtDNA@yahoogroups .com, Joe Merante <merantej@...> wrote:
                                    >
                                    >
                                    >
                                    > John,
                                    > I follow the forum although I am not an active participant; you always have extremely informative posts.
                                    > I was impressed by the fact that you had over 5,000 matches at the HVR1 level. I have taken the full sequence test. I have had zero matches at any level since I received the results of my test over two years ago. Is having no matches usual or unusual? DNACousins and Jim Logan both classified me as J1c1. My mito search ID is QXGKN.
                                    > Thanks
                                    > Joe Merante
                                    >
                                    >
                                    >
                                    > To: J-mtDNA@...: johnlloydscharf@ ...: Sun, 28 Dec 2008 03:10:41 +0000Subject: [J-mtDNA] Re: Haplogroup J1a* or J1c
                                    >
                                    >
                                    >
                                    >
                                    > If you have had your FGS done, you might find this 2004 thesis on J1 helpful:
                                    > http://class. csuhayward. edu/faculty/ gmiller/3710/ DNA_PDFS/ mtDNA/mtHap_ J_thesis. pdf
                                    > If FTDNA had a J3, it would be listed on www.mitosearch. org, which they support as a public database.
                                    > You cannot have an "exact match" with anyone based on HVR1. That can only be done with a FGS. I have over 5,000 matches at the HVR1 level. I have 290 at the HVR1/HVR2 level, of which 16 had been tested for FGS. I have NO matches on my FGS level of resolution.
                                    > That means those 16, which "match" at lower levels of resolution, are NOT a match at the FGS level. Unless you have a FGS, the term "exact match" certainly does not apply. I am not absolutely certain, but I think you could match at the FGS level and have very slight differences even though all your base pairs match.
                                    > --- In J-mtDNA@yahoogroups .com, "jcmooreii" jcmooreii@ wrote:>> But FTDNA must also use a classification scheme that would be > outdated, because they list a couple of my exact matches on my HVR1 as > J3, which I understand is outdated too. J Moore>
                                    >






                                    Life on your PC is safer, easier, and more enjoyable with Windows Vista®. See how
                                  • Hannah Lloyd
                                    Thanks. I usually think of elderly as being somewhere in the neighborhood of seventy +! And of course, short of immaculate conception, that kind of pregnancy
                                    Message 17 of 26 , Dec 31, 2008
                                    View Source
                                    • 0 Attachment
                                      Thanks.  I usually think of elderly as being somewhere in the neighborhood of seventy +!
                                      And of course, short of immaculate conception, that kind of pregnancy just
                                      wouldn't be possible.....

                                      On Dec 31, 2008, at 1:20 PM, Joe Merante wrote:

                                       
                                      Over 35.  And, i really should have said "older" as opposed to "elderly".


                                      To: J-mtDNA@yahoogroups .com
                                      From: hannahlloyd@ mac.com
                                      Date: Wed, 31 Dec 2008 12:48:46 -0500
                                      Subject: [J-mtDNA] elderly?


                                      What's an elderly mother? 

                                      On Dec 31, 2008, at 7:24 AM, Joe Merante wrote:

                                      John,
                                      Thank you for your thoughtful review.  Except for the tobacco, you seem to be hitting the right direction.  Elderly mothers were the norm for my maternal line for at leat three generation.  And, although my oldest maternal line records (mid 1700s) places this line in Italy, it is family lore that they came from Spain.
                                      I will ask my brother to test to compare.  Is HVR 1 sufficient, or should we do HVR 2 also.
                                      Again Thanks.
                                      Joe Merante





                                      To: J-mtDNA@yahoogroups .com
                                      From: johnlloydscharf@ yahoo.com
                                      Date: Mon, 29 Dec 2008 22:48:43 +0000
                                      Subject: [J-mtDNA] Re: Haplogroup J1a* or J1c


                                      I do not know what they may know in many areas.  I can only say what I can see by your QXGKN account. And the J1C1, though you listed yourself as J1b1. There is only one J1c1 in the database and he is from Spain, while the J1b1 has as many in that subclade, at www.mitosearch. org , as my H3. Most of the database is from the US and, therefore, tilted toward Scots-Irish. 
                                      You have two deletions in the HVR2, which by itself would be rare. J1c1 is rare as there is only one in the database listed as such. Given that, I cannot recommend you publish your FGS without some professional genetic consultation. 
                                      My SWAG, or Scientific Wild Atrophied Guess, is the following possibilities just to begin with:
                                      It could be nothing or it could be aging. It could be you had an elderly mother at birth in your lineage or you should have stopped chewing tobacco months before you gave up a sample. Not that it is related here at all, but some Vietnam Vets exposed to Agent Orange had changes in their mito. A check of muscle or blood mito could give different results. It is rare, but possible, as are the rest of this SWAG. 
                                      You may want to confirm your results with a mito relative. On the other hand, rare birds are more easily traced to a geographic/ethnic origin, in my opinion. Given so few of us have tested for the FGS, the more who take that option, the more resolution we get, even if we have a near miss. 
                                      Our DNA is compared with an H2 with some rare polymorhisms of an individual at Cambridge, rather than L3 out of Africa. That is the Cambridge in the Revised Cambridge Reference Sequence (rCRS). I have seen only one study that used L3.  The original CRS had mistakes in sequencing and contamination from a cow, so they had to resequence it. The individual involved still had seven rare polymorphisms, meaning she was not actually representative. An individual could have all seven of those and still be H2, from what I understand. 
                                      Just from the large numbers of polymorphisms you show in your HVR1/HVR2, you are very far from the H2, which a J1c1 would certainly be. I do not have a chart for J1 or your differences from the rCRS outside of the HVR1/HVR2, so I could not even begin to make inferences about your subclade or the areas it is likely from. 
                                      If we get into SWAG again, I would say your deep ancestry is from an Arab influx into the Iberian Peninsula at least 600 years ago. You just do not have enough information, yet, and you should hold SWAG on the same level as someone doing a read with Tarot cards, shuffled by a Scots-Irish descendent, because of the influence of the US on ordering mtDNA results. 

                                      --- In J-mtDNA@yahoogroups .com, Joe Merante <merantej@... > wrote:
                                      >
                                      > 
                                      > 
                                      > John,
                                      > I follow the forum although I am not an active participant; you always have extremely informative posts.
                                      > I was impressed by the fact that you had over 5,000 matches at the HVR1 level. I have taken the full sequence test. I have had zero matches at any level since I received the results of my test over two years ago. Is having no matches usual or unusual? DNACousins and Jim Logan both classified me as J1c1. My mito search ID is QXGKN.
                                      > Thanks
                                      > Joe Merante
                                      > 
                                      > 
                                      > 
                                      > To: J-mtDNA@...: johnlloydscharf@ ...: Sun, 28 Dec 2008 03:10:41 +0000Subject: [J-mtDNA] Re: Haplogroup J1a* or J1c
                                      > 
                                      > 
                                      > 
                                      > 
                                      > If you have had your FGS done, you might find this 2004 thesis on J1 helpful:
                                      > http://class. csuhayward. edu/faculty/ gmiller/3710/ DNA_PDFS/ mtDNA/mtHap_ J_thesis. pdf
                                      > If FTDNA had a J3, it would be listed on www.mitosearch. org, which they support as a public database. 
                                      > You cannot have an "exact match" with anyone based on HVR1. That can only be done with a FGS. I have over 5,000 matches at the HVR1 level. I have 290 at the HVR1/HVR2 level, of which 16 had been tested for FGS. I have NO matches on my FGS level of resolution.
                                      > That means those 16, which "match" at lower levels of resolution, are NOT a match at the FGS level. Unless you have a FGS, the term "exact match" certainly does not apply. I am not absolutely certain, but I think you could match at the FGS level and have very slight differences even though all your base pairs match. 
                                      > --- In J-mtDNA@yahoogroups .com, "jcmooreii" jcmooreii@ wrote:>> But FTDNA must also use a classification scheme that would be > outdated, because they list a couple of my exact matches on my HVR1 as > J3, which I understand is outdated too. J Moore>
                                      >






                                      Hannah Lloyd
                                        
                                      BGS CSAC
                                      Dr. Lewis Weber & Associates
                                      Tanglewood West Office Building
                                      Suite 348
                                      3959 Electric Road
                                      Roanoke, VA 24018
                                      work: 540 815-4214
                                      fax: 540 772-9119
                                      Addiction Recovery Resources for Professionals
                                                
                                      The information contained in this email and subsequent attachments may be privileged, confidential and protected from disclosure.  This transmission is intended for the sole use of the individual and entity to whom it is addressed.  If you are not the intended recipient, any dissemination, distribution or copying is strictly prohibited. If you have received this message in error, please email the sender at the above email address.








                                      Hannah Lloyd
                                        
                                      BGS CSAC
                                      Dr. Lewis Weber & Associates
                                      Tanglewood West Office Building
                                      Suite 348
                                      3959 Electric Road
                                      Roanoke, VA 24018
                                      work: 540 815-4214
                                      fax: 540 772-9119
                                      Addiction Recovery Resources for Professionals
                                                
                                      The information contained in this email and subsequent attachments may be privileged, confidential and protected from disclosure.  This transmission is intended for the sole use of the individual and entity to whom it is addressed.  If you are not the intended recipient, any dissemination, distribution or copying is strictly prohibited. If you have received this message in error, please email the sender at the above email address.




                                    • John Lloyd Scharf
                                      The issue of concern showed up with some deletions in your HVR2 of 522/523 that may play a role in aging. I do not actually see having your brother checked as
                                      Message 18 of 26 , Dec 31, 2008
                                      View Source
                                      • 0 Attachment
                                        The issue of concern showed up with some deletions in your HVR2 of
                                        522/523 that may play a role in aging. I do not actually see having
                                        your brother checked as useful, unless you think there is something
                                        wrong with the sample or if your age/exposure to toxins comes into play.

                                        I am curious in regard to the Italy/Spain thing, I wonder if you have
                                        ancestors both on Majorca and Sicily. That could cause the confusion.
                                        OR, it could be confusion caused by your paternal lineage.


                                        --- In J-mtDNA@yahoogroups.com, Joe Merante <merantej@...> wrote:
                                        >
                                        >
                                        > John,
                                        > Thank you for your thoughtful review. Except for the tobacco, you seem
                                        to be hitting the right direction. Elderly mothers were the norm for my
                                        maternal line for at leat three generation. And, although my oldest
                                        maternal line records (mid 1700s) places this line in Italy, it is
                                        family lore that they came from Spain.
                                        > I will ask my brother to test to compare. Is HVR 1 sufficient, or
                                        should we do HVR 2 also.
                                        > Again Thanks.
                                        > Joe Merante
                                        >
                                        >
                                        >
                                        > To: J-mtDNA@...: johnlloydscharf@...: Mon, 29 Dec 2008 22:48:43
                                        +0000Subject: [J-mtDNA] Re: Haplogroup J1a* or J1c
                                        >
                                        >
                                        >
                                        >
                                        > I do not know what they may know in many areas. I can only say what I
                                        can see by your QXGKN account. And the J1C1, though you listed yourself
                                        as J1b1. There is only one J1c1 in the database and he is from Spain,
                                        while the J1b1 has as many in that subclade, at www.mitosearch.org , as
                                        my H3. Most of the database is from the US and, therefore, tilted toward
                                        Scots-Irish.
                                        > You have two deletions in the HVR2, which by itself would be rare.
                                        J1c1 is rare as there is only one in the database listed as such. Given
                                        that, I cannot recommend you publish your FGS without some professional
                                        genetic consultation.
                                        > My SWAG, or Scientific Wild Atrophied Guess, is the following
                                        possibilities just to begin with:
                                        > It could be nothing or it could be aging. It could be you had an
                                        elderly mother at birth in your lineage or you should have stopped
                                        chewing tobacco months before you gave up a sample. Not that it is
                                        related here at all, but some Vietnam Vets exposed to Agent Orange had
                                        changes in their mito. A check of muscle or blood mito could give
                                        different results. It is rare, but possible, as are the rest of this
                                        SWAG.
                                        > You may want to confirm your results with a mito relative. On the
                                        other hand, rare birds are more easily traced to a geographic/ethnic
                                        origin, in my opinion. Given so few of us have tested for the FGS, the
                                        more who take that option, the more resolution we get, even if we have a
                                        near miss.
                                        > Our DNA is compared with an H2 with some rare polymorhisms of an
                                        individual at Cambridge, rather than L3 out of Africa. That is the
                                        Cambridge in the Revised Cambridge Reference Sequence (rCRS). I have
                                        seen only one study that used L3. The original CRS had mistakes in
                                        sequencing and contamination from a cow, so they had to resequence it.
                                        The individual involved still had seven rare polymorphisms, meaning she
                                        was not actually representative. An individual could have all seven of
                                        those and still be H2, from what I understand.
                                        > Just from the large numbers of polymorphisms you show in your
                                        HVR1/HVR2, you are very far from the H2, which a J1c1 would certainly
                                        be. I do not have a chart for J1 or your differences from the rCRS
                                        outside of the HVR1/HVR2, so I could not even begin to make inferences
                                        about your subclade or the areas it is likely from.
                                        > If we get into SWAG again, I would say your deep ancestry is from an
                                        Arab influx into the Iberian Peninsula at least 600 years ago. You just
                                        do not have enough information, yet, and you should hold SWAG on the
                                        same level as someone doing a read with Tarot cards, shuffled by a
                                        Scots-Irish descendent, because of the influence of the US on ordering
                                        mtDNA results.
                                        > --- In J-mtDNA@yahoogroups.com, Joe Merante merantej@ wrote:>> > >
                                        John,> I follow the forum although I am not an active participant; you
                                        always have extremely informative posts.> I was impressed by the fact
                                        that you had over 5,000 matches at the HVR1 level. I have taken the full
                                        sequence test. I have had zero matches at any level since I received the
                                        results of my test over two years ago. Is having no matches usual or
                                        unusual? DNACousins and Jim Logan both classified me as J1c1. My mito
                                        search ID is QXGKN.> Thanks> Joe Merante> > > > To: J-mtDNA@:
                                        johnlloydscharf@: Sun, 28 Dec 2008 03:10:41 +0000Subject: [J-mtDNA] Re:
                                        Haplogroup J1a* or J1c> > > > > If you have had your FGS done, you might
                                        find this 2004 thesis on J1 helpful:>
                                        http://class.csuhayward.edu/faculty/gmiller/3710/DNA_PDFS/mtDNA/mtHap_J_\
                                        thesis.pdf> If FTDNA had a J3, it would be listed on www.mitosearch.org,
                                        which they support as a public database. > You cannot have an "exact
                                        match" with anyone based on HVR1. That can only be done with a FGS. I
                                        have over 5,000 matches at the HVR1 level. I have 290 at the HVR1/HVR2
                                        level, of which 16 had been tested for FGS. I have NO matches on my FGS
                                        level of resolution.> That means those 16, which "match" at lower levels
                                        of resolution, are NOT a match at the FGS level. Unless you have a FGS,
                                        the term "exact match" certainly does not apply. I am not absolutely
                                        certain, but I think you could match at the FGS level and have very
                                        slight differences even though all your base pairs match. > --- In
                                        J-mtDNA@yahoogroups.com, "jcmooreii" jcmooreii@ wrote:>> But FTDNA must
                                        also use a classification scheme that would be > outdated, because they
                                        list a couple of my exact matches on my HVR1 as > J3, which I understand
                                        is outdated too. J Moore>>
                                        >
                                      • John Lloyd Scharf
                                        The best age, according to some older studies, is 23. Over the age of 40, childbearing can be an issue. We cannot go by anecdotal information. If there were
                                        Message 19 of 26 , Dec 31, 2008
                                        View Source
                                        • 0 Attachment
                                          The best age, according to some older studies, is 23. Over the age of
                                          40, childbearing can be an issue. We cannot go by anecdotal information.
                                          If there were not a concern, you would not have had the Downs Syndrome
                                          test.

                                          My X is an intelligent woman with medical problems typically due to age.
                                          Great teeth, too. She is an RN. Her father was 55 and her mother was 42
                                          when she was born in 1954. My father was 38 and my mother was 27 when I
                                          was born. I have the same medical problems as her. Both of us were
                                          injured and have problems due to that. We both have type 2 diabetes from
                                          being overweight. My father died in a car accident. My mother died of
                                          Altzheimer's at the age of 84. Her father died of heart disease and her
                                          mother of diabetes in their 80s. They were all active into their 70s.

                                          So, yes, age is not always a determinant with regard to genetic disease.
                                          It is just one of many factors.


                                          --- In J-mtDNA@yahoogroups.com, Judy Houck <houckjudy@...> wrote:
                                          >
                                          >
                                          > I had my third and last child at age 39. The first two were born in my
                                          early 20's.
                                          > This third one was a real suprise. I don't know if there were any DNA
                                          changes between the first two and the last. I did take the
                                          amniocentyesis (? spelling) test
                                          > and that only checks for Down syndrome which was negative. He has
                                          basically been normal since birth. Scores high on his school testing.
                                          >
                                          > Judy Carter
                                          >
                                          >
                                          >
                                          > To: j-mtdna@...: merantej@...: Wed, 31 Dec 2008 07:24:14 -0500Subject:
                                          RE: [J-mtDNA] Re: Haplogroup J1a* or J1c
                                          >
                                          >
                                          >
                                          > John,Thank you for your thoughtful review. Except for the tobacco, you
                                          seem to be hitting the right direction. Elderly mothers were the norm
                                          for my maternal line for at leat three generation. And, although my
                                          oldest maternal line records (mid 1700s) places this line in Italy, it
                                          is family lore that they came from Spain.I will ask my brother to test
                                          to compare. Is HVR 1 sufficient, or should we do HVR 2 also.Again
                                          Thanks.Joe Merante
                                          >
                                          > To: J-mtDNA@...: johnlloydscharf@...: Mon, 29 Dec 2008 22:48:43
                                          +0000Subject: [J-mtDNA] Re: Haplogroup J1a* or J1c
                                          >
                                          >
                                          >
                                          > I do not know what they may know in many areas. I can only say what I
                                          can see by your QXGKN account. And the J1C1, though you listed yourself
                                          as J1b1. There is only one J1c1 in the database and he is from Spain,
                                          while the J1b1 has as many in that subclade, at www.mitosearch.org , as
                                          my H3. Most of the database is from the US and, therefore, tilted toward
                                          Scots-Irish. You have two deletions in the HVR2, which by itself would
                                          be rare. J1c1 is rare as there is only one in the database listed as
                                          such. Given that, I cannot recommend you publish your FGS without some
                                          professional genetic consultation. My SWAG, or Scientific Wild Atrophied
                                          Guess, is the following possibilities just to begin with:It could be
                                          nothing or it could be aging. It could be you had an elderly mother at
                                          birth in your lineage or you should have stopped chewing tobacco months
                                          before you gave up a sample. Not that it is related here at all, but
                                          some Vietnam Vets exposed to Agent Orange had changes in their mito. A
                                          check of muscle or blood mito could give different results. It is rare,
                                          but possible, as are the rest of this SWAG. You may want to confirm your
                                          results with a mito relative. On the other hand, rare birds are more
                                          easily traced to a geographic/ethnic origin, in my opinion. Given so few
                                          of us have tested for the FGS, the more who take that option, the more
                                          resolution we get, even if we have a near miss. Our DNA is compared with
                                          an H2 with some rare polymorhisms of an individual at Cambridge, rather
                                          than L3 out of Africa. That is the Cambridge in the Revised Cambridge
                                          Reference Sequence (rCRS). I have seen only one study that used L3. The
                                          original CRS had mistakes in sequencing and contamination from a cow, so
                                          they had to resequence it. The individual involved still had seven rare
                                          polymorphisms, meaning she was not actually representative. An
                                          individual could have all seven of those and still be H2, from what I
                                          understand. Just from the large numbers of polymorphisms you show in
                                          your HVR1/HVR2, you are very far from the H2, which a J1c1 would
                                          certainly be. I do not have a chart for J1 or your differences from the
                                          rCRS outside of the HVR1/HVR2, so I could not even begin to make
                                          inferences about your subclade or the areas it is likely from. If we get
                                          into SWAG again, I would say your deep ancestry is from an Arab influx
                                          into the Iberian Peninsula at least 600 years ago. You just do not have
                                          enough information, yet, and you should hold SWAG on the same level as
                                          someone doing a read with Tarot cards, shuffled by a Scots-Irish
                                          descendent, because of the influence of the US on ordering mtDNA
                                          results. --- In J-mtDNA@yahoogroups.com, Joe Merante merantej@ wrote:>>
                                          > > John,> I follow the forum although I am not an active participant;
                                          you always have extremely informative posts.> I was impressed by the
                                          fact that you had over 5,000 matches at the HVR1 level. I have taken the
                                          full sequence test. I have had zero matches at any level since I
                                          received the results of my test over two years ago. Is having no matches
                                          usual or unusual? DNACousins and Jim Logan both classified me as J1c1.
                                          My mito search ID is QXGKN.> Thanks> Joe Merante> > > > To: J-mtDNA@:
                                          johnlloydscharf@: Sun, 28 Dec 2008 03:10:41 +0000Subject: [J-mtDNA] Re:
                                          Haplogroup J1a* or J1c> > > > > If you have had your FGS done, you might
                                          find this 2004 thesis on J1 helpful:>
                                          http://class.csuhayward.edu/faculty/gmiller/3710/DNA_PDFS/mtDNA/mtHap_J_\
                                          thesis.pdf> If FTDNA had a J3, it would be listed on www.mitosearch.org,
                                          which they support as a public database. > You cannot have an "exact
                                          match" with anyone based on HVR1. That can only be done with a FGS. I
                                          have over 5,000 matches at the HVR1 level. I have 290 at the HVR1/HVR2
                                          level, of which 16 had been tested for FGS. I have NO matches on my FGS
                                          level of resolution.> That means those 16, which "match" at lower levels
                                          of resolution, are NOT a match at the FGS level. Unless you have a FGS,
                                          the term "exact match" certainly does not apply. I am not absolutely
                                          certain, but I think you could match at the FGS level and have very
                                          slight differences even though all your base pairs match. > --- In
                                          J-mtDNA@yahoogroups.com, "jcmooreii" jcmooreii@ wrote:>> But FTDNA must
                                          also use a classification scheme that would be > outdated, because they
                                          list a couple of my exact matches on my HVR1 as > J3, which I understand
                                          is outdated too. J Moore>>
                                          >
                                          >
                                          >
                                          >
                                          >
                                          >
                                          > _________________________________________________________________
                                          > Life on your PC is safer, easier, and more enjoyable with Windows
                                          Vista®.
                                          > http://clk.atdmt.com/MRT/go/127032870/direct/01/
                                          >
                                        • Joe Merante
                                          John,Happy New Year. Either you are being very lucky in your guesses, or your knowledge of this topic is more than you will admit. I am actually in
                                          Message 20 of 26 , Jan 1, 2009
                                          View Source
                                          • 0 Attachment
                                            John,
                                            Happy New Year.
                                            Either you are being very lucky in your guesses, or your knowledge of this topic is more than you will admit.  I am actually in correspondence with a family in Majorca as they share a rare surname.  They also have documentary evidence showing a number of their family members left Majorca and Ibiza for Italy in the 1500s.
                                            Joe  






                                            To: J-mtDNA@yahoogroups.com
                                            From: johnlloydscharf@...
                                            Date: Wed, 31 Dec 2008 21:07:53 +0000
                                            Subject: [J-mtDNA] Re: Haplogroup J1a* or J1c




                                            The issue of concern showed up with some deletions in your HVR2 of
                                            522/523 that may play a role in aging. I do not actually see having
                                            your brother checked as useful, unless you think there is something
                                            wrong with the sample or if your age/exposure to toxins comes into play.

                                            I am curious in regard to the Italy/Spain thing, I wonder if you have
                                            ancestors both on Majorca and Sicily. That could cause the confusion.
                                            OR, it could be confusion caused by your paternal lineage.

                                            --- In J-mtDNA@yahoogroups .com, Joe Merante <merantej@.. .> wrote:
                                            >
                                            >
                                            > John,
                                            > Thank you for your thoughtful review. Except for the tobacco, you seem
                                            to be hitting the right direction. Elderly mothers were the norm for my
                                            maternal line for at leat three generation. And, although my oldest
                                            maternal line records (mid 1700s) places this line in Italy, it is
                                            family lore that they came from Spain.
                                            > I will ask my brother to test to compare. Is HVR 1 sufficient, or
                                            should we do HVR 2 also.
                                            > Again Thanks.
                                            > Joe Merante
                                            >
                                            >
                                            >
                                            > To: J-mtDNA@...: johnlloydscharf@ ...: Mon, 29 Dec 2008 22:48:43
                                            +0000Subject: [J-mtDNA] Re: Haplogroup J1a* or J1c
                                            >
                                            >
                                            >
                                            >
                                            > I do not know what they may know in many areas. I can only say what I
                                            can see by your QXGKN account. And the J1C1, though you listed yourself
                                            as J1b1. There is only one J1c1 in the database and he is from Spain,
                                            while the J1b1 has as many in that subclade, at www.mitosearch. org , as
                                            my H3. Most of the database is from the US and, therefore, tilted toward
                                            Scots-Irish.
                                            > You have two deletions in the HVR2, which by itself would be rare.
                                            J1c1 is rare as there is only one in the database listed as such. Given
                                            that, I cannot recommend you publish your FGS without some professional
                                            genetic consultation.
                                            > My SWAG, or Scientific Wild Atrophied Guess, is the following
                                            possibilities just to begin with:
                                            > It could be nothing or it could be aging. It could be you had an
                                            elderly mother at birth in your lineage or you should have stopped
                                            chewing tobacco months before you gave up a sample. Not that it is
                                            related here at all, but some Vietnam Vets exposed to Agent Orange had
                                            changes in their mito. A check of muscle or blood mito could give
                                            different results. It is rare, but possible, as are the rest of this
                                            SWAG.
                                            > You may want to confirm your results with a mito relative. On the
                                            other hand, rare birds are more easily traced to a geographic/ethnic
                                            origin, in my opinion. Given so few of us have tested for the FGS, the
                                            more who take that option, the more resolution we get, even if we have a
                                            near miss.
                                            > Our DNA is compared with an H2 with some rare polymorhisms of an
                                            individual at Cambridge, rather than L3 out of Africa. That is the
                                            Cambridge in the Revised Cambridge Reference Sequence (rCRS). I have
                                            seen only one study that used L3. The original CRS had mistakes in
                                            sequencing and contamination from a cow, so they had to resequence it.
                                            The individual involved still had seven rare polymorphisms, meaning she
                                            was not actually representative. An individual could have all seven of
                                            those and still be H2, from what I understand.
                                            > Just from the large numbers of polymorphisms you show in your
                                            HVR1/HVR2, you are very far from the H2, which a J1c1 would certainly
                                            be. I do not have a chart for J1 or your differences from the rCRS
                                            outside of the HVR1/HVR2, so I could not even begin to make inferences
                                            about your subclade or the areas it is likely from.
                                            > If we get into SWAG again, I would say your deep ancestry is from an
                                            Arab influx into the Iberian Peninsula at least 600 years ago. You just
                                            do not have enough information, yet, and you should hold SWAG on the
                                            same level as someone doing a read with Tarot cards, shuffled by a
                                            Scots-Irish descendent, because of the influence of the US on ordering
                                            mtDNA results.
                                            > --- In J-mtDNA@yahoogroups .com, Joe Merante merantej@ wrote:>> > >
                                            John,> I follow the forum although I am not an active participant; you
                                            always have extremely informative posts.> I was impressed by the fact
                                            that you had over 5,000 matches at the HVR1 level. I have taken the full
                                            sequence test. I have had zero matches at any level since I received the
                                            results of my test over two years ago. Is having no matches usual or
                                            unusual? DNACousins and Jim Logan both classified me as J1c1. My mito
                                            search ID is QXGKN.> Thanks> Joe Merante> > > > To: J-mtDNA@:
                                            johnlloydscharf@ : Sun, 28 Dec 2008 03:10:41 +0000Subject: [J-mtDNA] Re:
                                            Haplogroup J1a* or J1c> > > > > If you have had your FGS done, you might
                                            find this 2004 thesis on J1 helpful:>
                                            http://class. csuhayward. edu/faculty/ gmiller/3710/ DNA_PDFS/ mtDNA/mtHap_ J_\
                                            thesis.pdf
                                            > If FTDNA had a J3, it would be listed on www.mitosearch. org,
                                            which they support as a public database. > You cannot have an "exact
                                            match" with anyone based on HVR1. That can only be done with a FGS. I
                                            have over 5,000 matches at the HVR1 level. I have 290 at the HVR1/HVR2
                                            level, of which 16 had been tested for FGS. I have NO matches on my FGS
                                            level of resolution.> That means those 16, which "match" at lower levels
                                            of resolution, are NOT a match at the FGS level. Unless you have a FGS,
                                            the term "exact match" certainly does not apply. I am not absolutely
                                            certain, but I think you could match at the FGS level and have very
                                            slight differences even though all your base pairs match. > --- In
                                            J-mtDNA@yahoogroups .com, "jcmooreii" jcmooreii@ wrote:>> But FTDNA must
                                            also use a classification scheme that would be > outdated, because they
                                            list a couple of my exact matches on my HVR1 as > J3, which I understand
                                            is outdated too. J Moore>>
                                            >


                                          • Harry Watson
                                            There was a picture in my newspaper yesterday of an Indian woman of seventy who had just had her first baby. She had been trying for a baby for years!
                                            Message 21 of 26 , Jan 1, 2009
                                            View Source
                                            • 0 Attachment
                                              There was a picture in my newspaper yesterday of an Indian woman of seventy who had just had her first baby. She had been "trying for a baby" for years!

                                              Obstetricians in Britain have a great name for a first-time mother in her thirties or beyond - an "elderly prima gravida".

                                              Harry


                                              From: Hannah Lloyd <hannahlloyd@...>
                                              To: J-mtDNA@yahoogroups.com
                                              Sent: Wednesday, 31 December, 2008 7:15:25 PM
                                              Subject: Re: [J-mtDNA] elderly?

                                              Thanks.  I usually think of elderly as being somewhere in the neighborhood of seventy +!

                                              And of course, short of immaculate conception, that kind of pregnancy just
                                              wouldn't be possible.... .

                                              On Dec 31, 2008, at 1:20 PM, Joe Merante wrote:

                                               
                                              Over 35.  And, i really should have said "older" as opposed to "elderly".


                                              To: J-mtDNA@yahoogroups .com
                                              From: hannahlloyd@ mac.com
                                              Date: Wed, 31 Dec 2008 12:48:46 -0500
                                              Subject: [J-mtDNA] elderly?


                                              What's an elderly mother? 

                                              On Dec 31, 2008, at 7:24 AM, Joe Merante wrote:

                                              John,
                                              Thank you for your thoughtful review.  Except for the tobacco, you seem to be hitting the right direction.  Elderly mothers were the norm for my maternal line for at leat three generation.  And, although my oldest maternal line records (mid 1700s) places this line in Italy, it is family lore that they came from Spain.
                                              I will ask my brother to test to compare.  Is HVR 1 sufficient, or should we do HVR 2 also.
                                              Again Thanks.
                                              Joe Merante





                                              To: J-mtDNA@yahoogroups .com
                                              From: johnlloydscharf@ yahoo.com
                                              Date: Mon, 29 Dec 2008 22:48:43 +0000
                                              Subject: [J-mtDNA] Re: Haplogroup J1a* or J1c


                                              I do not know what they may know in many areas.  I can only say what I can see by your QXGKN account. And the J1C1, though you listed yourself as J1b1. There is only one J1c1 in the database and he is from Spain, while the J1b1 has as many in that subclade, at www.mitosearch. org , as my H3. Most of the database is from the US and, therefore, tilted toward Scots-Irish. 
                                              You have two deletions in the HVR2, which by itself would be rare. J1c1 is rare as there is only one in the database listed as such. Given that, I cannot recommend you publish your FGS without some professional genetic consultation. 
                                              My SWAG, or Scientific Wild Atrophied Guess, is the following possibilities just to begin with:
                                              It could be nothing or it could be aging. It could be you had an elderly mother at birth in your lineage or you should have stopped chewing tobacco months before you gave up a sample. Not that it is related here at all, but some Vietnam Vets exposed to Agent Orange had changes in their mito. A check of muscle or blood mito could give different results. It is rare, but possible, as are the rest of this SWAG. 
                                              You may want to confirm your results with a mito relative. On the other hand, rare birds are more easily traced to a geographic/ethnic origin, in my opinion. Given so few of us have tested for the FGS, the more who take that option, the more resolution we get, even if we have a near miss. 
                                              Our DNA is compared with an H2 with some rare polymorhisms of an individual at Cambridge, rather than L3 out of Africa. That is the Cambridge in the Revised Cambridge Reference Sequence (rCRS). I have seen only one study that used L3.  The original CRS had mistakes in sequencing and contamination from a cow, so they had to resequence it. The individual involved still had seven rare polymorphisms, meaning she was not actually representative. An individual could have all seven of those and still be H2, from what I understand. 
                                              Just from the large numbers of polymorphisms you show in your HVR1/HVR2, you are very far from the H2, which a J1c1 would certainly be. I do not have a chart for J1 or your differences from the rCRS outside of the HVR1/HVR2, so I could not even begin to make inferences about your subclade or the areas it is likely from. 
                                              If we get into SWAG again, I would say your deep ancestry is from an Arab influx into the Iberian Peninsula at least 600 years ago. You just do not have enough information, yet, and you should hold SWAG on the same level as someone doing a read with Tarot cards, shuffled by a Scots-Irish descendent, because of the influence of the US on ordering mtDNA results. 

                                              --- In J-mtDNA@yahoogroups .com, Joe Merante <merantej@... > wrote:
                                              >
                                              > 
                                              > 
                                              > John,
                                              > I follow the forum although I am not an active participant; you always have extremely informative posts.
                                              > I was impressed by the fact that you had over 5,000 matches at the HVR1 level. I have taken the full sequence test. I have had zero matches at any level since I received the results of my test over two years ago. Is having no matches usual or unusual? DNACousins and Jim Logan both classified me as J1c1. My mito search ID is QXGKN.
                                              > Thanks
                                              > Joe Merante
                                              > 
                                              > 
                                              > 
                                              > To: J-mtDNA@...: johnlloydscharf@ ...: Sun, 28 Dec 2008 03:10:41 +0000Subject: [J-mtDNA] Re: Haplogroup J1a* or J1c
                                              > 
                                              > 
                                              > 
                                              > 
                                              > If you have had your FGS done, you might find this 2004 thesis on J1 helpful:
                                              > http://class. csuhayward. edu/faculty/ gmiller/3710/ DNA_PDFS/ mtDNA/mtHap_ J_thesis. pdf
                                              > If FTDNA had a J3, it would be listed on www.mitosearch. org, which they support as a public database. 
                                              > You cannot have an "exact match" with anyone based on HVR1. That can only be done with a FGS. I have over 5,000 matches at the HVR1 level. I have 290 at the HVR1/HVR2 level, of which 16 had been tested for FGS. I have NO matches on my FGS level of resolution.
                                              > That means those 16, which "match" at lower levels of resolution, are NOT a match at the FGS level. Unless you have a FGS, the term "exact match" certainly does not apply. I am not absolutely certain, but I think you could match at the FGS level and have very slight differences even though all your base pairs match. 
                                              > --- In J-mtDNA@yahoogroups .com, "jcmooreii" jcmooreii@ wrote:>> But FTDNA must also use a classification scheme that would be > outdated, because they list a couple of my exact matches on my HVR1 as > J3, which I understand is outdated too. J Moore>
                                              >






                                              Hannah Lloyd
                                                
                                              BGS CSAC
                                              Dr. Lewis Weber & Associates
                                              Tanglewood West Office Building
                                              Suite 348
                                              3959 Electric Road
                                              Roanoke, VA 24018
                                              work: 540 815-4214
                                              fax: 540 772-9119
                                              Addiction Recovery Resources for Professionals
                                                        
                                              The information contained in this email and subsequent attachments may be privileged, confidential and protected from disclosure.  This transmission is intended for the sole use of the individual and entity to whom it is addressed.  If you are not the intended recipient, any dissemination, distribution or copying is strictly prohibited. If you have received this message in error, please email the sender at the above email address.








                                              Hannah Lloyd
                                                
                                              BGS CSAC
                                              Dr. Lewis Weber & Associates
                                              Tanglewood West Office Building
                                              Suite 348
                                              3959 Electric Road
                                              Roanoke, VA 24018
                                              work: 540 815-4214
                                              fax: 540 772-9119
                                              Addiction Recovery Resources for Professionals
                                                        
                                              The information contained in this email and subsequent attachments may be privileged, confidential and protected from disclosure.  This transmission is intended for the sole use of the individual and entity to whom it is addressed.  If you are not the intended recipient, any dissemination, distribution or copying is strictly prohibited. If you have received this message in error, please email the sender at the above email address.




                                            • J. J. (Jim) Logan
                                              John and others with a J3 designation form FTDNA: I contacted Family Tree DNA and asked about the motif for J3. I told them that from my research I could find
                                              Message 22 of 26 , Jan 2, 2009
                                              View Source
                                              • 0 Attachment
                                                John and others with a J3 designation form FTDNA:

                                                I contacted Family Tree DNA and asked about the motif for J3. I told
                                                them that from my research I could find no justification for just a
                                                classification. The response I received was in part: "As you can see
                                                form the below from Dr. Behar,He agrees with you...the 5 J3's in our
                                                system were old legacy data from > 19 months ago...they have been
                                                fixed!" The explanation included the statement: "The label J3 was
                                                coined by Herrnstadt et al. 2002. Late Palanichamy did not find
                                                justification for this as J3 is really one of J1c branches."

                                                If anyone still has a J3 showing on the personal page, please let me
                                                know and I will see if I can get it corrected.


                                                --- In J-mtDNA@yahoogroups.com, Moore <jcmooreii@...> wrote:
                                                >
                                                > Nevertheless, I do have 2 people, who ARE matches to me at the HVR1
                                                level, who are listed by FTDNA as "J3. Mr Logan has kindly given me a
                                                reference for the paper with the J3 classification, which definitely
                                                IS an old classification. Thus by uing the J3 for someone, they
                                                evidently ARE using an older scheme to classify people, or there is a
                                                typo. Plus, if these people in question do not belong to mitosearch,
                                                you may not be able to see there results.
                                                > Finally, I have a deep background in biological sciences and am not
                                                much impressed by "who wrote the book". Todays cutting edge can easily
                                                become old news tomorrow. J Moore
                                                >
                                              • mystere2e
                                                Please see my responses to John s post below. (He originally responded to Joe Merante re: J1c1.) I have denoted my start and end quotes with two
                                                Message 23 of 26 , Jan 3, 2009
                                                View Source
                                                • 0 Attachment
                                                  Please see my responses to John's post below. (He originally
                                                  responded to Joe Merante re: J1c1.) I have denoted my start and end
                                                  quotes with two << and >> symbols.


                                                  --- In J-mtDNA@yahoogroups.com, "John Lloyd Scharf" wrote:

                                                  You have two deletions in the HVR2, which by itself would be rare.
                                                  J1c1 is rare as there is only one in the database listed as such.
                                                  Given that, I cannot recommend you publish your FGS without some
                                                  professional genetic consultation.

                                                  <<I have the same deletions in HVR2, 522- and 523-, as Joe Merante
                                                  (his data was easy to find, since we are two of only three J1c1's on
                                                  MitoSearch). The other J1c1 on MitoSearch, from Cadiz, Spain, does
                                                  not have these deletions.

                                                  Why are these mutations so rare? And why should they make me think
                                                  twice before testing/publishing my FGS? Do these two deletions
                                                  indicate sensitive health information? (For the record, I do suffer
                                                  from some serious health problems.)>>

                                                  ...

                                                  It could be nothing or it could be aging. It could be you had an
                                                  elderly mother at birth in your lineage or you should have stopped
                                                  chewing tobacco months before you gave up a sample. Not that it is
                                                  related here at all, but some Vietnam Vets exposed to Agent Orange
                                                  had changes in their mito. A check of muscle or blood mito could give
                                                  different results. It is rare, but possible, as are the rest of this
                                                  SWAG.

                                                  <<I am 24 years old (and was 24 at the time of doing both tests, via
                                                  Genographic Project and then HVR1/HVR2 via FTDNA). At least for me,
                                                  the deletions at 522- and 523- cannot be due to aging. I have never
                                                  chewed tobacco and neither have any of the other women in my family,
                                                  at least back to my great-great-grandmother. No exposure to Agent
                                                  Orange, unless A.O. was circulating in the air in late 19th Century
                                                  Poland.

                                                  I have only traced my direct maternal lineage to 1835, and none of
                                                  the women were older than 34 at the time they gave birth to the next
                                                  direct descendant in line. However, there is certainly a possibility
                                                  further down the line that there was a daughter born of an older
                                                  woman. I am wondering, though, how giving birth at an older age would
                                                  cause deletions in her mtDNA, and why this would get passed down to
                                                  her daughter(s).>>

                                                  ...

                                                  I do not have a chart for J1 or your differences from the rCRS
                                                  outside of the HVR1/HVR2, so I could not even begin to make
                                                  inferences about your subclade or the areas it is likely from.

                                                  <<There are three J1c1's on MitoSearch.org right now. One tester
                                                  (Joe) is Italian, the other Spanish, and I am Polish. Other J1c1's
                                                  listed on FTDNA hail from England, Ireland, Scotland, Belgium and
                                                  Norway; my only HVR2 match is listed as being Swedish. So much for
                                                  narrowing my ancestral homeand down to a specific area!>>

                                                  ...

                                                  If we get into SWAG again, I would say your deep ancestry is from an
                                                  Arab influx into the Iberian Peninsula at least 600 years ago.

                                                  <<This is an interesting theory due to the fact my ancestors migrated
                                                  so far East (perhaps entering the Iberian Peninsula via Morocco, as
                                                  opposed to Egypt, as NatGeo proposes for a majority of Europeans,
                                                  right?)...

                                                  Does your Iberian Peninsula prediction cover J1c1 as a subclade, or
                                                  just the folks with the deletions at 522- and 523-?>>

                                                  ...

                                                  Sorry for hitting you with such a barrage of questions, but I found
                                                  your post very intriguing and I'm still reeling over FINALLY getting
                                                  my HVR2 results < 24 hours ago. :)

                                                  - Meg.
                                                • J. J. (Jim) Logan
                                                  Just a quick comment relative to the conversation below. 522- and 523- are not all that rare. They occur in almost 10% of the sequences in my reference
                                                  Message 24 of 26 , Jan 3, 2009
                                                  View Source
                                                  • 0 Attachment
                                                    Just a quick comment relative to the conversation below.  522- and 523- are not all that rare.  They occur in almost 10% of the sequences in my reference database.  I am not a medical doctor but from my research has not revealed these two deletions as having any medical significance.  For example, they are not listed in MITOMAP as associated with any disease.  (see my latest paper)
                                                    ====================
                                                    J. J. (Jim) Logan
                                                    Group Administrator, J-mtDNA, FxGS. and Logan DNA Projects
                                                    Owner/Moderator, J-mtDNA and GenGen-NV Discussion Groups on Yahoo
                                                    ===================================================================


                                                    mystere2e wrote:

                                                    Please see my responses to John's post below. (He originally
                                                    responded to Joe Merante re: J1c1.) I have denoted my start and end
                                                    quotes with two << and >> symbols.

                                                    --- In J-mtDNA@yahoogroups .com, "John Lloyd Scharf" wrote:

                                                    You have two deletions in the HVR2, which by itself would be rare.
                                                    J1c1 is rare as there is only one in the database listed as such.
                                                    Given that, I cannot recommend you publish your FGS without some
                                                    professional genetic consultation.

                                                    <<I have the same deletions in HVR2, 522- and 523-, as Joe Merante
                                                    (his data was easy to find, since we are two of only three J1c1's on
                                                    MitoSearch). The other J1c1 on MitoSearch, from Cadiz, Spain, does
                                                    not have these deletions.

                                                    Why are these mutations so rare? And why should they make me think
                                                    twice before testing/publishing my FGS? Do these two deletions
                                                    indicate sensitive health information? (For the record, I do suffer
                                                    from some serious health problems.)>>

                                                    ...

                                                    It could be nothing or it could be aging. It could be you had an
                                                    elderly mother at birth in your lineage or you should have stopped
                                                    chewing tobacco months before you gave up a sample. Not that it is
                                                    related here at all, but some Vietnam Vets exposed to Agent Orange
                                                    had changes in their mito. A check of muscle or blood mito could give
                                                    different results. It is rare, but possible, as are the rest of this
                                                    SWAG.

                                                    <<I am 24 years old (and was 24 at the time of doing both tests, via
                                                    Genographic Project and then HVR1/HVR2 via FTDNA). At least for me,
                                                    the deletions at 522- and 523- cannot be due to aging. I have never
                                                    chewed tobacco and neither have any of the other women in my family,
                                                    at least back to my great-great- grandmother. No exposure to Agent
                                                    Orange, unless A.O. was circulating in the air in late 19th Century
                                                    Poland.

                                                    I have only traced my direct maternal lineage to 1835, and none of
                                                    the women were older than 34 at the time they gave birth to the next
                                                    direct descendant in line. However, there is certainly a possibility
                                                    further down the line that there was a daughter born of an older
                                                    woman. I am wondering, though, how giving birth at an older age would
                                                    cause deletions in her mtDNA, and why this would get passed down to
                                                    her daughter(s). >>

                                                    ...

                                                    I do not have a chart for J1 or your differences from the rCRS
                                                    outside of the HVR1/HVR2, so I could not even begin to make
                                                    inferences about your subclade or the areas it is likely from.

                                                    <<There are three J1c1's on MitoSearch.org right now. One tester
                                                    (Joe) is Italian, the other Spanish, and I am Polish. Other J1c1's
                                                    listed on FTDNA hail from England, Ireland, Scotland, Belgium and
                                                    Norway; my only HVR2 match is listed as being Swedish. So much for
                                                    narrowing my ancestral homeand down to a specific area!>>

                                                    ...

                                                    If we get into SWAG again, I would say your deep ancestry is from an
                                                    Arab influx into the Iberian Peninsula at least 600 years ago.

                                                    <<This is an interesting theory due to the fact my ancestors migrated
                                                    so far East (perhaps entering the Iberian Peninsula via Morocco, as
                                                    opposed to Egypt, as NatGeo proposes for a majority of Europeans,
                                                    right?)...

                                                    Does your Iberian Peninsula prediction cover J1c1 as a subclade, or
                                                    just the folks with the deletions at 522- and 523-?>>

                                                    ...

                                                    Sorry for hitting you with such a barrage of questions, but I found
                                                    your post very intriguing and I'm still reeling over FINALLY getting
                                                    my HVR2 results < 24 hours ago. :)

                                                    - Meg.

                                                  • mawilson5158
                                                    23andme with V2 do 3024 (sorted of sorts not numerically though) I have cut and pasted the results into a spreadsheet which I can email if anyone wants it. SNP
                                                    Message 25 of 26 , Mar 1, 2009
                                                    View Source
                                                    • 0 Attachment
                                                      23andme with V2 do 3024 (sorted of sorts not numerically though)

                                                      I have cut and pasted the results into a spreadsheet which I can email
                                                      if anyone wants it.

                                                      SNP Versions Genotypes
                                                      10002 (10001) i3000877 C or T
                                                      10002 (10001) i3000877 C or T
                                                      10015 (10014) i3000878 A or G
                                                      10015 (10014) i3000878 A or G
                                                      10016 (10015) rs28374827 A or T
                                                      10016 (10015) rs28374827 A or T
                                                      10032 (10031) i4000966 C or T
                                                      10032 (10031) i4000966 C or T
                                                      10035 (10034) rs41347846 C or T
                                                      10035 (10034) i3001500 C or T
                                                      10035 (10034) rs41347846 C or T
                                                      10035 (10034) i3001500 C or T
                                                      10043 (10042) i3000879 A or G
                                                      10043 (10042) i3000879 A or G
                                                      10045 (10044) rs41362547 A or G
                                                      10045 (10044) rs41362547 A or G
                                                      1007 (1005) i3001961 C or T
                                                      10080 (10079) i4000960 A or C
                                                      10080 (10079) i4000960 A or C
                                                      10085 (10084) i3000880 C or T
                                                      10085 (10084) i3000880 C or T
                                                      10087 (10086) rs28358274 A or G
                                                      10087 (10086) rs28358274 A or G
                                                      10101 (10100) i3000881 C or T
                                                      10101 (10100) i3000881 C or T
                                                      10104 (10103) i3000882 A or G
                                                      10104 (10103) i3000882 A or G
                                                      10105 (10104) i3000884 A or C
                                                      10105 (10104) i3000884 A or C
                                                      10119 (10118) i4001149 C or T
                                                      10119 (10118) i4001149 C or T
                                                      10125 (10124) i4001148 C or T
                                                      10125 (10124) i4001148 C or T
                                                      10143 (10142) i3000885 C or T
                                                      10143 (10142) i3000885 C or T
                                                      10144 (10143) i3000886 A or G
                                                      10144 (10143) i3000886 A or G
                                                      10152 (10151) i4001078 A or G
                                                      10152 (10151) i4001078 A or G
                                                      10160 (10159) i3000887 C or G
                                                      10160 (10159) i3000887 C or G
                                                      10164 (10163) i3000888 A or C
                                                      10164 (10163) i3000888 A or C
                                                      10167 (10166) i3000889 C or T
                                                      10167 (10166) i3000889 C or T
                                                      10173 (10172) i3000890 A or G
                                                      10173 (10172) i3000890 A or G
                                                      10185 (10184) i3000895 C or G
                                                      10185 (10184) i3000895 C or G
                                                      10189 (10188) i4000714 A or G
                                                      10189 (10188) i4000714 A or G
                                                      10193 (10192) i3000896 C or T
                                                      10193 (10192) i3000896 C or T
                                                      10212 (10211) i3000897 C or T
                                                      10212 (10211) i3000897 C or T
                                                      10215 (10214) i4000713 C or T
                                                      10215 (10214) i4000713 C or T
                                                      10216 (10215) i3000898 A or G
                                                      10216 (10215) i3000898 A or G
                                                      10218 (10217) i3000899 A or G
                                                      10218 (10217) i3000899 A or G
                                                      10233 (10232) i3000900 A or G
                                                      10233 (10232) i3000900 A or G
                                                      10239 (10238) rs28358275 C or T
                                                      10239 (10238) rs28358275 C or T
                                                      10246 (10245) i3000902 C or T
                                                      10246 (10245) i3000902 C or T
                                                      10254 (10253) i4001205 C or T
                                                      10254 (10253) i4001205 C or T
                                                      10263 (10262) i3000903 A or G
                                                      10263 (10262) i3000903 A or G
                                                      10276 (10275) i4001206 C or T
                                                      10276 (10275) i4001206 C or T
                                                      10290 (10289) i3000905 A or G
                                                      10290 (10289) i3000905 A or G
                                                      103 (103) i3001685 A or G
                                                      10311 (10310) rs41467651 A or G
                                                      10311 (10310) i3001502 A or G
                                                      10311 (10310) rs41467651 A or G
                                                      10311 (10310) i3001502 A or G
                                                      10320 (10319) i3000907 A or G
                                                      10320 (10319) i3000907 A or G
                                                      10321 (10320) i3000908 A or G
                                                      10321 (10320) i3000908 A or G
                                                      10322 (10321) rs28358276 C or T
                                                      10322 (10321) rs28358276 C or T
                                                      10326 (10325) i3000909 A or G
                                                      10326 (10325) i3000909 A or G
                                                      10331 (10330) i3000910 C or T
                                                      10331 (10330) i3000910 C or T
                                                      10337 (10336) i3000911 C or T
                                                      10337 (10336) i3000911 C or T
                                                      10346 (10345) i4000905 C or T
                                                      10346 (10345) i4000905 C or T
                                                      10354 (10353) rs28435660 A or G
                                                      10354 (10353) rs28435660 A or G
                                                      10357 (10356) rs28457866 C or G
                                                      10357 (10356) rs28457866 C or G
                                                      10374 (10373) rs28358277 A or G
                                                      10374 (10373) i3000915 A or G
                                                      10374 (10373) rs28358277 A or G
                                                      10374 (10373) i3000915 A or G
                                                      10380 (10379) i4000901 A or G
                                                      10380 (10379) i4000901 A or G
                                                      10386 (10385) i3000916 A or C
                                                      10386 (10385) i3000916 A or C
                                                      10388 (10387) i3000917 C or G
                                                      10388 (10387) i3000917 C or G
                                                      10390 (10389) i3000919 C or T
                                                      10390 (10389) i3000919 C or T
                                                      10395 (10394) i4000829 C or T
                                                      10395 (10394) i4000829 C or T
                                                      10398 (10397) i3000920 A or G
                                                      10398 (10397) i3000920 A or G
                                                      10399 (10398) rs2853826 A or G
                                                      10399 (10398) rs2853826 A or G
                                                      10401 (10400) rs28358278 C or T
                                                      10401 (10400) rs28358278 C or T
                                                      10402 (10401) rs28719882 A or G
                                                      10402 (10401) rs28719882 A or G
                                                      10411 (10410) i3000921 C or T
                                                      10411 (10410) i3000921 C or T
                                                      10412 (10411) i4000828 A or G
                                                      10412 (10411) i4000828 A or G
                                                      10424 (10423) i3000922 A or G
                                                      10424 (10423) i3000922 A or G
                                                      10428 (10427) i3000924 A or G
                                                      10428 (10427) i3000924 A or G
                                                      1043 (1041) i3001962 A or G
                                                      10449 (10448) i3000925 C or T
                                                      10449 (10448) i3000925 C or T
                                                      10455 (10454) i3000926 C or T
                                                      10455 (10454) i3000926 C or T
                                                      10458 (10457) i3000927 C or T
                                                      10458 (10457) i3000927 C or T
                                                      10464 (10463) rs28358279 C or T
                                                      10464 (10463) rs28358279 C or T
                                                      1049 (1047) i3001964 A or G
                                                      10494 (10493) i4000710 C or T
                                                      10494 (10493) i4000710 C or T
                                                      10498 (10497) i4000711 C or T
                                                      10498 (10497) i4000711 C or T
                                                      105 (105) i3001696 C or T
                                                      1050 (1048) rs2000974 C or T
                                                      10500 (10499) i3000928 A or G
                                                      10500 (10499) i3000928 A or G
                                                      10507 (10506) i3000929 A or G
                                                      10507 (10506) i3000929 A or G
                                                      10522 (10521) rs28735641 A or G
                                                      10522 (10521) rs28735641 A or G
                                                      10536 (10535) i3000930 C or T
                                                      10536 (10535) i3000930 C or T
                                                      10539 (10538) i3000931 C or T
                                                      10539 (10538) i3000931 C or T
                                                      10551 (10550) rs28358280 A or G
                                                      10551 (10550) rs28358280 A or G
                                                      10573 (10572) rs28520241 A or G
                                                      10573 (10572) rs28520241 A or G
                                                      10576 (10575) i3000933 A or G
                                                      10576 (10575) i3000933 A or G
                                                      10587 (10586) rs28358281 A or G
                                                      10587 (10586) i3002609 A or G
                                                      10587 (10586) rs28358281 A or G
                                                      10587 (10586) i3002609 A or G
                                                      10590 (10589) rs2853487 A or G
                                                      10590 (10589) rs2853487 A or G
                                                      10591 (10590) rs28532736 G or T
                                                      10591 (10590) rs28532736 G or T
                                                      10601 (10600) i4000833 C or T
                                                      10601 (10600) i4000833 C or T
                                                      10602 (10601) i3000934 C or T
                                                      10602 (10601) i3000934 C or T
                                                      10605 (10604) i3000935 C or T
                                                      10605 (10604) i3000935 C or T
                                                      10608 (10607) i3000936 C or T
                                                      10608 (10607) i3000936 C or T
                                                      10610 (10609) i3000937 C or T
                                                      10610 (10609) i3000937 C or T
                                                      10611 (10610) i4000830 A or G
                                                      10611 (10610) i4000830 A or G
                                                      10620 (10619) i4000831 C or T
                                                      10620 (10619) i4000831 C or T
                                                      10638 (10637) i4000832 C or T
                                                      10638 (10637) i4000832 C or T
                                                      10640 (10639) i3000938 A or G
                                                      10640 (10639) i3000938 A or G
                                                      10641 (10640) i3000939 C or T
                                                      10641 (10640) i3000939 C or T
                                                      10647 (10646) i3000940 A or G
                                                      10647 (10646) i3000940 A or G
                                                      10659 (10658) i4000910 A or G
                                                      10659 (10658) i4000910 A or G
                                                      10665 (10664) rs2854121 C or T
                                                      10665 (10664) rs2854121 C or T
                                                      10686 (10685) i3000943 A or G
                                                      10686 (10685) i3000943 A or G
                                                      10689 (10688) rs2853488 A or G
                                                      10689 (10688) rs2853488 A or G
                                                      10698 (10697) i4000911 C or T
                                                      10698 (10697) i4000911 C or T
                                                      10705 (10704) rs28437034 A or G
                                                      10705 (10704) rs28437034 A or G
                                                      10707 (10706) rs3928311 C or T
                                                      10707 (10706) rs3928311 C or T
                                                      10708 (10707) i4000913 G or T
                                                      10708 (10707) i4000913 G or T
                                                      10713 (10712) rs3902408 C or T
                                                      10713 (10712) rs3902408 C or T
                                                      10734 (10733) rs28709356 A or C
                                                      10734 (10733) i3000947 C or T
                                                      10734 (10733) rs28709356 A or C
                                                      10734 (10733) i3000947 C or T
                                                      10743 (10742) i3000948 G or T
                                                      10743 (10742) i3000948 G or T
                                                      10758 (10757) i4001341 C or T
                                                      10758 (10757) i4001341 C or T
                                                      10787 (10786) i4001342 C or T
                                                      10787 (10786) i4001342 C or T
                                                      10791 (10790) rs28488153 C or T
                                                      10791 (10790) rs28488153 C or T
                                                      10802 (10801) i3000953 A or G
                                                      10802 (10801) i3000953 A or G
                                                      10811 (10810) rs28358282 C or T
                                                      10811 (10810) i3000954 C or T
                                                      10811 (10810) rs28358282 C or T
                                                      10811 (10810) i3000954 C or T
                                                      10817 (10816) i3000955 A or T
                                                      10817 (10816) i3000955 A or T
                                                      10820 (10819) rs28358283 A or G
                                                      10820 (10819) i3000956 A or G
                                                      10820 (10819) rs28358283 A or G
                                                      10820 (10819) i3000956 A or G
                                                      10826 (10825) i3000957 A or G
                                                      10826 (10825) i3000957 A or G
                                                      10833 (10832) i3000958 A or G
                                                      10833 (10832) i3000958 A or G
                                                      10835 (10834) i3000959 C or T
                                                      10835 (10834) i3000959 C or T
                                                      10875 (10874) i3000961 C or T
                                                      10875 (10874) i3000961 C or T
                                                      10877 (10876) i3000963 A or G
                                                      10877 (10876) i3000963 A or G
                                                      10883 (10882) rs28589650 C or T
                                                      10883 (10882) rs28589650 C or T
                                                      10886 (10885) i4000576 C or T
                                                      10886 (10885) i4000575 A or T
                                                      10886 (10885) i4000576 C or T
                                                      10886 (10885) i4000575 A or T
                                                      10891 (10890) i3000964 A or T
                                                      10891 (10890) i3000964 A or T
                                                      10895 (10894) i3000965 C or T
                                                      10895 (10894) i3000965 C or T
                                                      10896 (10895) i4000577 A or G
                                                      10896 (10895) i4000577 A or G
                                                      10900 (10899) i4000578 A or G
                                                      10900 (10899) i4000578 A or G
                                                      10904 (10903) i3000966 C or T
                                                      10904 (10903) i3000966 C or T
                                                      10908 (10907) i3000967 C or T
                                                      10908 (10907) i3000967 C or T
                                                      10915 (10914) i4000579 A or G
                                                      10915 (10914) i4000579 A or G
                                                      10916 (10915) rs2857285 C or T
                                                      10916 (10915) rs2857285 C or T
                                                      10928 (10927) i3000968 C or T
                                                      10928 (10927) i3000968 C or T
                                                      10947 (10946) i4000629 A or G
                                                      10947 (10946) i4000629 A or G
                                                      10955 (10954) i4000627 C or T
                                                      10955 (10954) i4000627 C or T
                                                      10967 (10966) i3000969 C or T
                                                      10967 (10966) i3000969 C or T
                                                      1097 (1095) i4000628 C or T
                                                      10973 (10972) i4000626 A or G
                                                      10973 (10972) i4000626 A or G
                                                      10977 (10976) i4000625 C or T
                                                      10977 (10976) i4000625 C or T
                                                      10985 (10984) rs2857286 C or G
                                                      10985 (10984) rs2857286 C or G
                                                      10987 (10986) i3000973 A or C
                                                      10987 (10986) i3000973 A or C
                                                      10994 (10993) i3000975 A or G
                                                      10994 (10993) i3000975 A or G
                                                      11003 (11002) i3000977 A or G
                                                      11003 (11002) i3000977 A or G
                                                      11014 (11013) i3000978 C or T
                                                      11014 (11013) i3000978 C or T
                                                      11016 (11015) i4001228 A or G
                                                      11016 (11015) i4001228 A or G
                                                      11017 (11016) i4001229 A or G
                                                      11017 (11016) i4001229 A or G
                                                      11018 (11017) rs28594904 C or T
                                                      11018 (11017) rs28594904 C or T
                                                      11021 (11020) i4001230 A or G
                                                      11021 (11020) i4001230 A or G
                                                      11026 (11025) i3000979 C or T
                                                      11026 (11025) i3000979 C or T
                                                      11042 (11041) i4001284 C or T
                                                      11042 (11041) i4001284 C or T
                                                      11045 (11044) i4001286 C or T
                                                      11045 (11044) i4001286 C or T
                                                      11062 (11061) i4001285 C or T
                                                      11062 (11061) i4001285 C or T
                                                      11066 (11065) i4001287 A or G
                                                      11066 (11065) i4001287 A or G
                                                      11076 (11075) i3000981 C or T
                                                      11076 (11075) i3000981 C or T
                                                      11079 (11078) i4001288 A or G
                                                      11079 (11078) i4001288 A or G
                                                      11084 (11083) i4001289 A or G
                                                      11084 (11083) i4001289 A or G
                                                      11085 (11084) i3000982 A or G
                                                      11085 (11084) i3000982 A or G
                                                      11088 (11087) rs28433448 C or T
                                                      11088 (11087) rs28433448 C or T
                                                      1109 (1107) i3001965 C or T
                                                      11108 (11107) i3000985 C or T
                                                      11108 (11107) i3000985 C or T
                                                      11113 (11112) i3000986 A or T
                                                      11113 (11112) i3000986 A or T
                                                      11121 (11120) i3000987 C or T
                                                      11121 (11120) i3000987 C or T
                                                      11131 (11130) i3000988 A or C
                                                      11131 (11130) i3000988 A or C
                                                      11141 (11140) i3000989 C or T
                                                      11141 (11140) i3000989 C or T
                                                      11147 (11146) rs3134800 C or T
                                                      11147 (11146) rs3134800 C or T
                                                      11152 (11151) i4000572 C or T
                                                      11152 (11151) i4000572 C or T
                                                      11155 (11154) i3000997 C or T
                                                      11155 (11154) i3000997 C or T
                                                      11159 (11158) i4000570 C or T
                                                      11159 (11158) i4000570 C or T
                                                      11168 (11167) i4000571 A or G
                                                      11168 (11167) i4000571 A or G
                                                      11169 (11168) i3000998 A or G
                                                      11169 (11168) i3000998 A or G
                                                      11173 (11172) rs2853489 A or G
                                                      11173 (11172) rs2853489 A or G
                                                      11177 (11176) rs2853490 A or G
                                                      11177 (11176) rs2853490 A or G
                                                      11178 (11177) rs28358284 C or T
                                                      11178 (11177) rs28358284 C or T
                                                      11186 (11185) i3000999 A or C
                                                      11186 (11185) i3000999 A or C
                                                      11187 (11186) rs28617734 C or T
                                                      11187 (11186) rs28617734 C or T
                                                      1119 (1117) i4000573 A or G
                                                      11198 (11197) i3001000 C or T
                                                      11198 (11197) i3001000 C or T
                                                      11205 (11204) i4000515 C or T
                                                      11205 (11204) i4000515 C or T
                                                      11207 (11206) rs28756874 A or C
                                                      11207 (11206) rs28756874 A or C
                                                      1121 (1119) i3001966 C or T
                                                      11216 (11215) i3001003 C or T
                                                      11216 (11215) i3001003 C or T
                                                      11238 (11237) rs28546714 A or C
                                                      11238 (11237) rs28546714 A or C
                                                      11252 (11251) rs3915952 A or G
                                                      11252 (11251) rs3915952 A or G
                                                      11254 (11253) i4001336 C or T
                                                      11254 (11253) i4001336 C or T
                                                      11255 (11254) i4001337 C or T
                                                      11255 (11254) i4001337 C or T
                                                      11256 (11255) i4001340 C or T
                                                      11256 (11255) i4001340 C or T
                                                      11258 (11257) i3001007 C or T
                                                      11258 (11257) i3001007 C or T
                                                      11261 (11260) i4001338 C or T
                                                      11261 (11260) i4001338 C or T
                                                      11279 (11278) i4001335 A or G
                                                      11279 (11278) i4001335 A or G
                                                      11289 (11288) i3001008 C or T
                                                      11289 (11288) i3001008 C or T
                                                      11297 (11296) i3001009 C or T
                                                      11297 (11296) i3001009 C or T
                                                      11300 (11299) rs28358285 C or T
                                                      11300 (11299) rs28358285 C or T
                                                      11331 (11330) i3001011 C or G
                                                      11331 (11330) i3001011 C or G
                                                      11333 (11332) i3001012 C or T
                                                      11333 (11332) i3001012 C or T
                                                      11336 (11335) rs2853491 C or T
                                                      11336 (11335) rs2853491 C or T
                                                      11340 (11339) i4001282 C or T
                                                      11340 (11339) i4001282 C or T
                                                      11349 (11348) i4001281 C or T
                                                      11349 (11348) i4001281 C or T
                                                      11351 (11350) i3001013 A or G
                                                      11351 (11350) i3001013 A or G
                                                      11354 (11353) i4001280 C or T
                                                      11354 (11353) i4001280 C or T
                                                      11363 (11362) i4001279 A or G
                                                      11363 (11362) i4001279 A or G
                                                      11366 (11365) rs28609979 C or T
                                                      11366 (11365) rs28609979 C or T
                                                      11378 (11377) rs41537746 A or G
                                                      11378 (11377) i3001505 A or G
                                                      11378 (11377) rs41537746 A or G
                                                      11378 (11377) i3001505 A or G
                                                      11381 (11380) i3001014 A or G
                                                      11381 (11380) i3001014 A or G
                                                      11384 (11383) i4001222 C or T
                                                      11384 (11383) i4001222 C or T
                                                      11395 (11394) i3001015 C or T
                                                      11395 (11394) i3001015 C or T
                                                      114 (114) i3001726 C or T
                                                      11441 (11440) i3001017 A or G
                                                      11441 (11440) i3001017 A or G
                                                      11466 (11465) i3001019 C or T
                                                      11466 (11465) i3001019 C or T
                                                      11468 (11467) rs2853493 A or G
                                                      11468 (11467) rs2853493 A or G
                                                      11471 (11470) i3001020 A or G
                                                      11471 (11470) i3001020 A or G
                                                      11475 (11474) rs28371977 A or G
                                                      11475 (11474) rs28371977 A or G
                                                      11477 (11476) i4000751 C or T
                                                      11477 (11476) i4000751 C or T
                                                      11480 (11479) rs28524151 A or C
                                                      11480 (11479) rs28524151 A or C
                                                      11483 (11482) i3001021 C or T
                                                      11483 (11482) i3001021 C or T
                                                      11486 (11485) rs28529320 C or T
                                                      11486 (11485) rs28529320 C or T
                                                      11498 (11497) i3001022 C or G
                                                      11498 (11497) i3001022 C or G
                                                      115 (115) i3001736 C or T
                                                      11504 (11503) i3001023 C or T
                                                      11504 (11503) i3001023 C or T
                                                      11548 (11547) rs28588421 G or T
                                                      11548 (11547) rs28588421 G or T
                                                      11550 (11549) i4001096 C or T
                                                      11550 (11549) i4001096 C or T
                                                      11554 (11553) i3001025 C or G
                                                      11554 (11553) i3001025 C or G
                                                      11555 (11554) i4001095 C or T
                                                      11555 (11554) i4001095 C or T
                                                      11561 (11560) i3001026 A or G
                                                      11561 (11560) i3001026 A or G
                                                      11611 (11610) i3001030 C or T
                                                      11611 (11610) i3001030 C or T
                                                      11612 (11611) i4001163 A or G
                                                      11612 (11611) i4001163 A or G
                                                      11618 (11617) i3001031 G or T
                                                      11618 (11617) i3001031 G or T
                                                      1162 (1160) i3001967 A or G
                                                      11621 (11620) i3001032 A or G
                                                      11621 (11620) i3001032 A or G
                                                      11624 (11623) i3001033 C or T
                                                      11624 (11623) i3001033 C or T
                                                      11627 (11626) i4001165 C or T
                                                      11627 (11626) i4001165 C or T
                                                      11642 (11641) rs2853494 A or G
                                                      11642 (11641) rs2853494 A or G
                                                      11648 (11647) i3001036 C or T
                                                      11648 (11647) i3001036 C or T
                                                      11654 (11653) i4001092 A or G
                                                      11654 (11653) i4001092 A or G
                                                      11666 (11665) i3002668 C or T
                                                      11666 (11665) i3002668 C or T
                                                      11675 (11674) rs28358286 C or T
                                                      11675 (11674) rs28358286 C or T
                                                      11697 (11696) i3001042 A or G
                                                      11697 (11696) i3001042 A or G
                                                      1170 (1168) rs28477561 A or G
                                                      11720 (11719) i3001044 A or G
                                                      11720 (11719) i3001044 A or G
                                                      11733 (11732) i3001045 C or T
                                                      11733 (11732) i3001045 C or T
                                                      11778 (11777) rs28384199 C or G
                                                      11778 (11777) rs28384199 C or G
                                                      11789 (11788) i3001050 C or T
                                                      11789 (11788) i3001050 C or T
                                                      11795 (11794) i3001051 C or T
                                                      11795 (11794) i3001051 C or T
                                                      11808 (11807) i3001053 A or G
                                                      11808 (11807) i3001053 A or G
                                                      11810 (11809) i4000778 C or T
                                                      11810 (11809) i4000778 C or T
                                                      11813 (11812) rs3088053 A or G
                                                      11813 (11812) rs3088053 A or G
                                                      11820 (11819) rs28439211 C or G
                                                      11820 (11819) rs28439211 C or G
                                                      11828 (11827) i4000580 C or T
                                                      11828 (11827) i4000580 C or T
                                                      11841 (11840) rs28550734 C or T
                                                      11841 (11840) rs28550734 C or T
                                                      11844 (11843) rs28713729 A or G
                                                      11844 (11843) rs28713729 A or G
                                                      11861 (11860) i3001058 C or G
                                                      11861 (11860) i3001058 C or G
                                                      11882 (11881) i3001059 C or G
                                                      11882 (11881) i3001059 C or G
                                                      11894 (11893) i3001060 A or G
                                                      11894 (11893) i3001060 A or G
                                                      119 (119) i3001746 C or T
                                                      11900 (11899) rs28718242 C or T
                                                      11900 (11899) i3001506 C or T
                                                      11900 (11899) rs28718242 C or T
                                                      11900 (11899) i3001506 C or T
                                                      11903 (11902) i3001061 C or G
                                                      11903 (11902) i3001061 C or G
                                                      1191 (1189) rs28358571 C or T
                                                      11915 (11914) rs2853496 A or G
                                                      11915 (11914) rs2853496 A or G
                                                      1192 (1190) i3001968 C or T
                                                      11924 (11923) i4001016 A or G
                                                      11924 (11923) i4001016 A or G
                                                      11929 (11928) i4001017 A or G
                                                      11929 (11928) i4001017 A or G
                                                      11930 (11929) rs28722520 G or T
                                                      11930 (11929) rs28722520 G or T
                                                      11936 (11935) i3001062 C or T
                                                      11936 (11935) i3001062 C or T
                                                      11939 (11938) i3001063 C or T
                                                      11939 (11938) i3001063 C or T
                                                      1194 (1192) i3001969 A or C
                                                      11948 (11947) rs28359168 A or G
                                                      11948 (11947) i3001065 A or G
                                                      11948 (11947) rs28359168 A or G
                                                      11948 (11947) i3001065 A or G
                                                      1195 (1193) i4001018 C or T
                                                      11954 (11953) i3001067 C or T
                                                      11954 (11953) i3001067 C or T
                                                      11957 (11956) rs3087900 C or T
                                                      11957 (11956) rs3087900 C or T
                                                      1196 (1194) rs28495504 A or C
                                                      11960 (11959) i4000698 A or G
                                                      11960 (11959) i4000698 A or G
                                                      11979 (11978) i3001070 A or T
                                                      11979 (11978) i3001070 A or T
                                                      120 (120) i3001756 C or G
                                                      12008 (12007) rs2853497 A or G
                                                      12008 (12007) rs2853497 A or G
                                                      12027 (12026) i3001071 A or G
                                                      12027 (12026) i3001071 A or G
                                                      12031 (12030) i4000899 A or G
                                                      12031 (12030) i4000899 A or G
                                                      12050 (12049) i4000898 C or T
                                                      12050 (12049) i4000898 C or T
                                                      12054 (12053) rs28639786 C or T
                                                      12054 (12053) rs28639786 C or T
                                                      12065 (12064) i4000897 C or T
                                                      12065 (12064) i4000897 C or T
                                                      12071 (12070) i3001072 A or G
                                                      12071 (12070) i3001072 A or G
                                                      12084 (12083) i3001073 G or T
                                                      12084 (12083) i3001073 G or T
                                                      12085 (12084) i3001075 C or T
                                                      12085 (12084) i3001075 C or T
                                                      12086 (12085) i4000900 C or T
                                                      12086 (12085) i4000900 C or T
                                                      12089 (12088) i4000708 C or T
                                                      12089 (12088) i4000708 C or T
                                                      12092 (12091) rs28415973 C or T
                                                      12092 (12091) rs28415973 C or T
                                                      12093 (12092) i3001076 C or T
                                                      12093 (12092) i3001076 C or T
                                                      12103 (12102) i3001077 C or T
                                                      12103 (12102) i3001077 C or T
                                                      12113 (12112) rs28695839 C or G
                                                      12113 (12112) rs28695839 C or G
                                                      12122 (12121) i4000704 C or T
                                                      12122 (12121) i4000704 C or T
                                                      12128 (12127) i4000705 A or G
                                                      12128 (12127) i4000705 A or G
                                                      1213 (1211) i4000707 A or G
                                                      12136 (12135) i3001079 A or C
                                                      12136 (12135) i3001079 A or C
                                                      12154 (12153) i3001080 C or T
                                                      12154 (12153) i3001080 C or T
                                                      12172 (12171) i3001081 A or G
                                                      12172 (12171) i3001081 A or G
                                                      12173 (12172) i3001082 A or G
                                                      12173 (12172) i3001082 A or G
                                                      12174 (12173) i3001083 A or T
                                                      12174 (12173) i3001083 A or T
                                                      12176 (12175) i3001084 C or T
                                                      12176 (12175) i3001084 C or T
                                                      12190 (12189) rs28505538 C or T
                                                      12190 (12189) i3001088 C or T
                                                      12190 (12189) rs28505538 C or T
                                                      12190 (12189) i3001088 C or T
                                                      12193 (12192) rs3134560 A or G
                                                      12193 (12192) rs3134560 A or G
                                                      12198 (12197) rs28711184 C or T
                                                      12198 (12197) rs28711184 C or T
                                                      12201 (12200) i3001089 A or G
                                                      12201 (12200) i3001089 A or G
                                                      12208 (12207) i4000574 A or G
                                                      12208 (12207) i4000574 A or G
                                                      12237 (12236) rs28359170 A or G
                                                      12237 (12236) rs28359170 A or G
                                                      12240 (12239) i3001092 C or T
                                                      12240 (12239) i3001092 C or T
                                                      12247 (12246) rs28508189 C or G
                                                      12247 (12246) rs28508189 C or G
                                                      12249 (12248) i3001094 A or G
                                                      12249 (12248) i3001094 A or G
                                                      12259 (12258) i3001096 A or C
                                                      12259 (12258) i3001096 A or C
                                                      12276 (12275) rs28469108 A or G
                                                      12276 (12275) rs28469108 A or G
                                                      12293 (12292) i3001098 G or T
                                                      12293 (12292) i3001098 G or T
                                                      12299 (12298) i3001099 C or T
                                                      12299 (12298) i3001099 C or T
                                                      12301 (12300) rs28493891 A or G
                                                      12301 (12300) rs28493891 A or G
                                                      12309 (12308) rs2853498 A or G
                                                      12309 (12308) rs2853498 A or G
                                                      12312 (12311) i3001100 C or T
                                                      12312 (12311) i3001100 C or T
                                                      12332 (12331) i3001101 A or G
                                                      12332 (12331) i3001101 A or G
                                                      12339 (12338) i3001102 C or T
                                                      12339 (12338) i3001102 C or T
                                                      12347 (12346) i3001103 C or T
                                                      12347 (12346) i3001103 C or T
                                                      12359 (12358) i3001106 A or G
                                                      12359 (12358) i3001106 A or G
                                                      12361 (12360) i3001107 C or T
                                                      12361 (12360) i3001107 C or T
                                                      12362 (12361) rs3134561 A or G
                                                      12362 (12361) rs3134561 A or G
                                                      12371 (12370) i4000772 C or T
                                                      12371 (12370) i4000772 C or T
                                                      12372 (12371) rs28452651 G or T
                                                      12372 (12371) rs28452651 G or T
                                                      12373 (12372) rs2853499 A or G
                                                      12373 (12372) rs2853499 A or G
                                                      12377 (12376) i3001108 G or T
                                                      12377 (12376) i3001108 G or T
                                                      12385 (12384) i3001109 C or T
                                                      12385 (12384) i3001109 C or T
                                                      12386 (12385) i3001110 C or T
                                                      12386 (12385) i3001110 C or T
                                                      12391 (12390) i4000776 C or T
                                                      12391 (12390) i4000776 C or T
                                                      12395 (12394) rs28709525 C or T
                                                      12395 (12394) rs28709525 C or T
                                                      12398 (12397) i4000775 A or G
                                                      12398 (12397) i4000775 A or G
                                                      12399 (12398) i4000716 C or T
                                                      12399 (12398) i4000716 C or T
                                                      12400 (12399) i3001111 C or T
                                                      12400 (12399) i3001111 C or T
                                                      12404 (12403) i3001112 C or T
                                                      12404 (12403) i3001112 C or T
                                                      12406 (12405) i3001113 C or T
                                                      12406 (12405) i3001113 C or T
                                                      12407 (12406) rs28617389 A or G
                                                      12407 (12406) rs28617389 A or G
                                                      12415 (12414) rs41520546 C or T
                                                      12415 (12414) i3001509 C or T
                                                      12415 (12414) rs41520546 C or T
                                                      12415 (12414) i3001509 C or T
                                                      12419 (12418) i3001116 A or C
                                                      12419 (12418) i3001116 A or C
                                                      12424 (12423) i4000719 A or G
                                                      12424 (12423) i4000719 A or G
                                                      12426 (12425) i4000921 A or G
                                                      12426 (12425) i4000921 A or G
                                                      12442 (12441) i3001117 C or T
                                                      12442 (12441) i3001117 C or T
                                                      1245 (1243) rs28358572 C or T
                                                      12462 (12461) i3001119 C or G
                                                      12462 (12461) i3001119 C or G
                                                      12470 (12469) i4000920 A or G
                                                      12470 (12469) i4000920 A or G
                                                      12478 (12477) rs28608480 C or T
                                                      12478 (12477) rs28608480 C or T
                                                      12485 (12484) i3001121 C or G
                                                      12485 (12484) i3001121 C or G
                                                      12499 (12498) i4000840 C or T
                                                      12499 (12498) i4000840 C or T
                                                      125 (125) i3001777 G or T
                                                      12502 (12501) rs28397767 A or G
                                                      12502 (12501) rs28397767 A or G
                                                      12511 (12510) i4000841 C or T
                                                      12511 (12510) i4000841 C or T
                                                      12520 (12519) rs28359171 C or T
                                                      12520 (12519) rs28359171 C or T
                                                      12562 (12561) rs28759201 A or G
                                                      12562 (12561) rs28759201 A or G
                                                      12569 (12568) rs28411793 A or C
                                                      12569 (12568) rs28411793 A or C
                                                      12584 (12583) i3001125 A or G
                                                      12584 (12583) i3001125 A or G
                                                      12610 (12609) i4001030 C or T
                                                      12610 (12609) i4001030 C or T
                                                      12613 (12612) rs28359172 A or G
                                                      12613 (12612) rs28359172 A or G
                                                      12619 (12618) i3001126 A or G
                                                      12619 (12618) i3001126 A or G
                                                      12621 (12620) i3001127 C or T
                                                      12621 (12620) i3001127 C or T
                                                      12622 (12621) i4001032 C or T
                                                      12622 (12621) i4001032 C or T
                                                      12631 (12630) rs41445245 A or G
                                                      12631 (12630) i3001510 A or G
                                                      12631 (12630) rs41445245 A or G
                                                      12631 (12630) i3001510 A or G
                                                      12634 (12633) rs3926883 A or C
                                                      12634 (12633) i3001129 C or T
                                                      12634 (12633) rs3926883 A or C
                                                      12634 (12633) i3001129 C or T
                                                      12643 (12642) i3001131 A or G
                                                      12643 (12642) i3001131 A or G
                                                      1265 (1263) i3001973 C or G
                                                      12652 (12651) i4000972 A or G
                                                      12652 (12651) i4000972 A or G
                                                      12655 (12654) i3001132 A or G
                                                      12655 (12654) i3001132 A or G
                                                      12670 (12669) rs41369547 C or T
                                                      12670 (12669) i3001511 C or T
                                                      12670 (12669) rs41369547 C or T
                                                      12670 (12669) i3001511 C or T
                                                      12673 (12672) i3001133 A or C
                                                      12673 (12672) i3001133 A or C
                                                      12675 (12674) i3001134 A or G
                                                      12675 (12674) i3001134 A or G
                                                      12685 (12684) rs28410409 A or G
                                                      12685 (12684) rs28410409 A or G
                                                      12697 (12696) i3001135 C or T
                                                      12697 (12696) i3001135 C or T
                                                      127 (127) i4001167 C or T
                                                      12715 (12714) i4001169 C or T
                                                      12715 (12714) i4001169 C or T
                                                      12721 (12720) rs2853500 A or G
                                                      12721 (12720) rs2853500 A or G
                                                      12728 (12727) i3001136 C or T
                                                      12728 (12727) i3001136 C or T
                                                      12733 (12732) i4001168 C or T
                                                      12733 (12732) i4001168 C or T
                                                      12739 (12738) i3001137 G or T
                                                      12739 (12738) i3001137 G or T
                                                      12759 (12758) i3001140 G or T
                                                      12759 (12758) i3001140 G or T
                                                      12763 (12762) rs28379632 A or C
                                                      12763 (12762) rs28379632 A or C
                                                      12766 (12765) i4001094 C or T
                                                      12766 (12765) i4001094 C or T
                                                      12769 (12768) rs28591518 A or G
                                                      12769 (12768) rs28591518 A or G
                                                      12772 (12771) i3001141 A or G
                                                      12772 (12771) i3001141 A or G
                                                      12774 (12773) i3001142 A or G
                                                      12774 (12773) i3001142 A or G
                                                      12778 (12777) i4001093 A or G
                                                      12778 (12777) i4001093 A or G
                                                      128 (128) i3001807 C or T
                                                      12811 (12810) rs28359174 A or G
                                                      12811 (12810) rs28359174 A or G
                                                      12812 (12811) i3001144 C or T
                                                      12812 (12811) i3001144 C or T
                                                      12816 (12815) i3001145 C or T
                                                      12816 (12815) i3001145 C or T
                                                      12817 (12816) i4001277 C or T
                                                      12817 (12816) i4001277 C or T
                                                      12832 (12831) i4001274 C or T
                                                      12832 (12831) i4001274 C or T
                                                      12845 (12844) rs28668242 C or G
                                                      12845 (12844) rs28668242 C or G
                                                      12851 (12850) rs28705385 A or G
                                                      12851 (12850) rs28705385 A or G
                                                      12853 (12852) i4001276 C or T
                                                      12853 (12852) i4001276 C or T
                                                      12859 (12858) i4001275 C or T
                                                      12859 (12858) i4001275 C or T
                                                      12865 (12864) i3001147 C or T
                                                      12865 (12864) i3001147 C or T
                                                      12880 (12879) i4001273 C or T
                                                      12880 (12879) i4001273 C or T
                                                      12881 (12880) rs28719001 G or T
                                                      12881 (12880) rs28719001 G or T
                                                      12883 (12882) i3001149 C or T
                                                      12883 (12882) i3001149 C or T
                                                      1290 (1288) i3001974 C or G
                                                      12904 (12903) i3001150 C or T
                                                      12904 (12903) i3001150 C or T
                                                      12908 (12907) rs28690070 C or T
                                                      12908 (12907) rs28690070 C or T
                                                      12938 (12937) i3001152 A or G
                                                      12938 (12937) i3001152 A or G
                                                      12941 (12940) i3001153 A or G
                                                      12941 (12940) i3001153 A or G
                                                      12949 (12948) i4001220 A or G
                                                      12949 (12948) i4001220 A or G
                                                      12951 (12950) i3001154 A or G
                                                      12951 (12950) i3001154 A or G
                                                      12958 (12957) i3001155 C or T
                                                      12958 (12957) i3001155 C or T
                                                      12964 (12963) i4001225 C or T
                                                      12964 (12963) i4001225 C or T
                                                      12974 (12973) i3001156 C or T
                                                      12974 (12973) i3001156 C or T
                                                      13016 (13015) i3001158 C or T
                                                      13016 (13015) i3001158 C or T
                                                      13018 (13017) i4001255 A or G
                                                      13018 (13017) i4001255 A or G
                                                      13021 (13020) i3001160 C or T
                                                      13021 (13020) i3001160 C or T
                                                      13030 (13029) rs28448767 C or T
                                                      13030 (13029) rs28448767 C or T
                                                      1305 (1303) i3001975 A or G
                                                      13051 (13050) i4000677 A or G
                                                      13051 (13050) i4000677 A or G
                                                      13066 (13065) i3002648 C or T
                                                      13066 (13065) i3002648 C or T
                                                      13069 (13068) i3001163 A or G
                                                      13069 (13068) i3001163 A or G
                                                      13073 (13072) rs28703131 C or T
                                                      13073 (13072) rs28703131 C or T
                                                      131 (131) i3001817 C or T
                                                      13102 (13101) i3001165 A or C
                                                      13102 (13101) i3001165 A or C
                                                      13105 (13104) i3001166 A or G
                                                      13105 (13104) i3001166 A or G
                                                      13106 (13105) rs2853501 A or G
                                                      13106 (13105) rs2853501 A or G
                                                      13112 (13111) i4000922 C or T
                                                      13112 (13111) i4000922 C or T
                                                      13118 (13117) i3001167 A or G
                                                      13118 (13117) i3001167 A or G
                                                      1312 (1310) i3001977 C or T
                                                      13136 (13135) i3001170 A or G
                                                      13136 (13135) i3001170 A or G
                                                      13144 (13143) i3001171 C or T
                                                      13144 (13143) i3001171 C or T
                                                      13146 (13145) i3001172 A or G
                                                      13146 (13145) i3001172 A or G
                                                      13153 (13152) i3001173 A or G
                                                      13153 (13152) i3001173 A or G
                                                      13162 (13161) i3001174 C or T
                                                      13162 (13161) i3001174 C or T
                                                      13175 (13174) i4000513 C or T
                                                      13175 (13174) i4000513 C or T
                                                      13195 (13194) i3001177 A or G
                                                      13195 (13194) i3001177 A or G
                                                      132 (132) i3001828 C or G
                                                      13207 (13206) rs28542790 C or T
                                                      13207 (13206) rs28542790 C or T
                                                      13216 (13215) i3001179 C or T
                                                      13216 (13215) i3001179 C or T
                                                      13255 (13254) i4000709 C or T
                                                      13255 (13254) i4000709 C or T
                                                      13259 (13258) i3001183 A or T
                                                      13259 (13258) i3001183 A or T
                                                      13264 (13263) rs28359175 A or G
                                                      13264 (13263) rs28359175 A or G
                                                      13267 (13266) i3001184 A or G
                                                      13267 (13266) i3001184 A or G
                                                      13270 (13269) rs28604589 A or G
                                                      13270 (13269) rs28604589 A or G
                                                      13277 (13276) rs2853502 A or G
                                                      13277 (13276) rs2853502 A or G
                                                      13279 (13278) i3001185 A or G
                                                      13279 (13278) i3001185 A or G
                                                      13282 (13281) i3001186 C or T
                                                      13282 (13281) i3001186 C or T
                                                      1329 (1327) rs28394599 A or G
                                                      13294 (13293) i4001330 C or T
                                                      13294 (13293) i4001330 C or T
                                                      13316 (13315) rs28619081 C or T
                                                      13316 (13315) rs28619081 C or T
                                                      13327 (13326) i3001187 C or T
                                                      13327 (13326) i3001187 C or T
                                                      13351 (13350) i4001331 A or G
                                                      13351 (13350) i4001331 A or G
                                                      13358 (13357) i4000623 A or G
                                                      13358 (13357) i4000623 A or G
                                                      13360 (13359) i4000702 C or G
                                                      13360 (13359) i4000702 C or G
                                                      13369 (13368) rs3899498 A or G
                                                      13369 (13368) rs3899498 A or G
                                                      13396 (13395) i3001190 A or G
                                                      13396 (13395) i3001190 A or G
                                                      13402 (13401) rs28379170 C or T
                                                      13402 (13401) rs28379170 C or T
                                                      13405 (13404) i3001191 C or T
                                                      13405 (13404) i3001191 C or T
                                                      13414 (13413) i3001192 A or G
                                                      13414 (13413) i3001192 A or G
                                                      1343 (1341) i3001979 C or T
                                                      13435 (13434) i3001193 A or G
                                                      13435 (13434) i3001193 A or G
                                                      13438 (13437) i4000700 C or T
                                                      13438 (13437) i4000700 C or T
                                                      13467 (13466) rs3902404 A or G
                                                      13467 (13466) rs3902404 A or G
                                                      13478 (13477) i3001194 A or G
                                                      13478 (13477) i3001194 A or G
                                                      1348 (1346) i3001980 A or G
                                                      13493 (13492) rs28376363 C or G
                                                      13493 (13492) rs28376363 C or G
                                                      13501 (13500) i3001512 C or T
                                                      13501 (13500) i3001512 C or T
                                                      13507 (13506) rs2857287 C or T
                                                      13507 (13506) rs2857287 C or T
                                                      13546 (13545) i3001198 C or T
                                                      13546 (13545) i3001198 C or T
                                                      13550 (13549) i3001199 A or G
                                                      13550 (13549) i3001199 A or G
                                                      13564 (13563) i3001200 A or G
                                                      13564 (13563) i3001200 A or G
                                                      13597 (13596) i4000723 C or G
                                                      13597 (13596) i4000723 C or G
                                                      13610 (13609) rs28439808 C or G
                                                      13610 (13609) rs28439808 C or G
                                                      13618 (13617) i3001202 C or T
                                                      13618 (13617) i3001202 C or T
                                                      13624 (13623) i4000940 C or T
                                                      13624 (13623) i4000940 C or T
                                                      13627 (13626) i3001204 C or T
                                                      13627 (13626) i3001204 C or T
                                                      13636 (13635) i4000720 C or T
                                                      13636 (13635) i4000720 C or T
                                                      13638 (13637) i3001205 A or G
                                                      13638 (13637) i3001205 A or G
                                                      13657 (13656) i3001206 C or T
                                                      13657 (13656) i3001206 C or T
                                                      13681 (13680) i3001207 C or T
                                                      13681 (13680) i3001207 C or T
                                                      13682 (13681) i3001208 A or G
                                                      13682 (13681) i3001208 A or G
                                                      13703 (13702) rs2853813 C or G
                                                      13703 (13702) rs2853813 C or G
                                                      13705 (13704) i3001210 C or T
                                                      13705 (13704) i3001210 C or T
                                                      13709 (13708) rs28359178 A or G
                                                      13709 (13708) rs28359178 A or G
                                                      13712 (13711) i3001214 A or G
                                                      13712 (13711) i3001214 A or G
                                                      13735 (13734) i3001217 C or T
                                                      13735 (13734) i3001217 C or T
                                                      13736 (13735) i3001218 A or C
                                                      13736 (13735) i3001218 A or C
                                                      13741 (13740) rs28630861 C or T
                                                      13741 (13740) rs28630861 C or T
                                                      13744 (13743) i3001219 C or T
                                                      13744 (13743) i3001219 C or T
                                                      13753 (13752) i3001220 C or T
                                                      13753 (13752) i3001220 C or T
                                                      1376 (1374) rs28673100 A or T
                                                      13760 (13759) i3001221 A or G
                                                      13760 (13759) i3001221 A or G
                                                      13769 (13768) i3001223 C or T
                                                      13769 (13768) i3001223 C or T
                                                      13781 (13780) rs41358152 A or G
                                                      13781 (13780) i3001513 A or G
                                                      13781 (13780) rs41358152 A or G
                                                      13781 (13780) i3001513 A or G
                                                      13790 (13789) rs28359179 C or T
                                                      13790 (13789) rs28359179 C or T
                                                      1380 (1378) rs28612532 C or T
                                                      13803 (13802) i3001224 C or T
                                                      13803 (13802) i3001224 C or T
                                                      1381 (1379) rs28729254 A or C
                                                      13812 (13811) i4001086 C or G
                                                      13812 (13811) i4001086 C or G
                                                      13819 (13818) i4001083 C or T
                                                      13819 (13818) i4001083 C or T
                                                      1382 (1380) rs28573951 A or G
                                                      13822 (13821) i3001226 C or T
                                                      13822 (13821) i3001226 C or T
                                                      13828 (13827) i3001228 A or G
                                                      13828 (13827) i3001228 A or G
                                                      13831 (13830) i3001229 C or T
                                                      13831 (13830) i3001229 C or T
                                                      1384 (1382) i3001982 A or C
                                                      13849 (13848) i3001232 C or T
                                                      13849 (13848) i3001232 C or T
                                                      13856 (13855) rs3925298 C or T
                                                      13856 (13855) rs3925298 C or T
                                                      13857 (13856) i3001233 A or T
                                                      13857 (13856) i3001233 A or T
                                                      13880 (13879) i3001234 C or T
                                                      13880 (13879) i3001234 C or T
                                                      13881 (13880) rs28359181 A or C
                                                      13881 (13880) rs28359181 A or C
                                                      13886 (13885) i3001235 A or C
                                                      13886 (13885) i3001235 A or C
                                                      13887 (13886) rs28359182 C or T
                                                      13887 (13886) rs28359182 C or T
                                                      13891 (13890) i3001236 C or T
                                                      13891 (13890) i3001236 C or T
                                                      13894 (13893) i3001237 A or T
                                                      13894 (13893) i3001237 A or T
                                                      13900 (13899) i3001238 C or T
                                                      13900 (13899) i3001238 C or T
                                                      1391 (1389) rs28493131 G or T
                                                      13915 (13914) rs28359183 A or C
                                                      13915 (13914) rs28359183 A or C
                                                      13928 (13927) i4000970 A or G
                                                      13928 (13927) i4000970 A or G
                                                      13929 (13928) rs28359184 C or G
                                                      13929 (13928) rs28359184 C or G
                                                      1393 (1391) i4000969 C or T
                                                      13935 (13934) i3001243 C or T
                                                      13935 (13934) i3001243 C or T
                                                      13949 (13948) i4000542 C or T
                                                      13949 (13948) i4000542 C or T
                                                      1395 (1393) i3001983 A or G
                                                      13959 (13958) i4000552 C or G
                                                      13959 (13958) i4000562 A or G
                                                      13959 (13958) i4000552 C or G
                                                      13959 (13958) i4000562 A or G
                                                      13966 (13965) rs41509754 C or T
                                                      13966 (13965) i3001515 C or T
                                                      13966 (13965) rs41509754 C or T
                                                      13966 (13965) i3001515 C or T
                                                      13968 (13967) i3001244 C or T
                                                      13968 (13967) i3001244 C or T
                                                      14004 (14003) i3001246 C or T
                                                      14004 (14003) i3001246 C or T
                                                      14017 (14016) rs41484851 A or G
                                                      14017 (14016) rs41484851 A or G
                                                      14021 (14020) i3001249 C or T
                                                      14021 (14020) i3001249 C or T
                                                      14023 (14022) i4001328 A or G
                                                      14023 (14022) i4001328 A or G
                                                      14026 (14025) i4001329 C or T
                                                      14026 (14025) i4001329 C or T
                                                      14041 (14040) i4001327 A or G
                                                      14041 (14040) i4001327 A or G
                                                      14050 (14049) rs3900944 C or T
                                                      14050 (14049) rs3900944 C or T
                                                      14054 (14053) i3001250 A or G
                                                      14054 (14053) i3001250 A or G
                                                      14060 (14059) i4001269 A or G
                                                      14060 (14059) i4001269 A or G
                                                      14068 (14067) i4001271 C or T
                                                      14068 (14067) i4001271 C or T
                                                      1408 (1406) i4001268 C or T
                                                      14089 (14088) rs28359186 C or T
                                                      14089 (14088) rs28359186 C or T
                                                      14095 (14094) i4001212 C or T
                                                      14095 (14094) i4001212 C or T
                                                      14097 (14096) i3001256 A or G
                                                      14097 (14096) i3001256 A or G
                                                      14098 (14097) i4001211 C or T
                                                      14098 (14097) i4001211 C or T
                                                      14111 (14110) i3001257 C or T
                                                      14111 (14110) i3001257 C or T
                                                      1412 (1410) rs28392533 A or G
                                                      14129 (14128) i4001215 A or G
                                                      14129 (14128) i4001215 A or G
                                                      14138 (14137) i4000633 C or T
                                                      14138 (14137) i4000633 C or T
                                                      14140 (14139) i3001260 A or G
                                                      14140 (14139) i3001260 A or G
                                                      14143 (14142) i4000632 C or T
                                                      14143 (14142) i4000632 C or T
                                                      14149 (14148) rs28357668 A or G
                                                      14149 (14148) rs28357668 A or G
                                                      14153 (14152) rs28357669 A or G
                                                      14153 (14152) rs28357669 A or G
                                                      14168 (14167) rs28357670 C or T
                                                      14168 (14167) rs28357670 C or T
                                                      1417 (1415) i4000631 A or G
                                                      14174 (14173) i3001261 C or T
                                                      14174 (14173) i3001261 C or T
                                                      14179 (14178) rs28357671 C or T
                                                      14179 (14178) i3001517 C or T
                                                      14179 (14178) rs28357671 C or T
                                                      14179 (14178) i3001517 C or T
                                                      14181 (14180) i3001262 C or T
                                                      14181 (14180) i3001262 C or T
                                                      14183 (14182) i3001263 C or T
                                                      14183 (14182) i3001263 C or T
                                                      1420 (1418) rs28366503 A or G
                                                      14204 (14203) rs34657896 A or G
                                                      14204 (14203) rs34657896 A or G
                                                      14213 (14212) rs28357672 C or T
                                                      14213 (14212) i3002604 C or T
                                                      14213 (14212) rs28357672 C or T
                                                      14213 (14212) i3002604 C or T
                                                      14234 (14233) rs3915611 A or G
                                                      14234 (14233) rs3915611 A or G
                                                      14260 (14259) i3001271 A or G
                                                      14260 (14259) i3001271 A or G
                                                      14267 (14266) i4001343 C or T
                                                      14267 (14266) i4001343 C or T
                                                      14273 (14272) rs2853814 C or G
                                                      14273 (14272) rs2853814 C or G
                                                      14285 (14284) rs28357673 C or T
                                                      14285 (14284) rs28357673 C or T
                                                      14300 (14299) i3001274 C or T
                                                      14300 (14299) i3001274 C or T
                                                      14306 (14305) i3001276 A or G
                                                      14306 (14305) i3001276 A or G
                                                      14309 (14308) i3001277 C or T
                                                      14309 (14308) i3001277 C or T
                                                      14315 (14314) i3001278 A or G
                                                      14315 (14314) i3001278 A or G
                                                      14319 (14318) rs28357675 C or T
                                                      14319 (14318) rs28357675 C or T
                                                      14324 (14323) i3001279 A or G
                                                      14324 (14323) i3001279 A or G
                                                      14341 (14340) i3001282 C or T
                                                      14341 (14340) i3001282 C or T
                                                      14365 (14364) i3001283 A or G
                                                      14365 (14364) i3001283 A or G
                                                      14366 (14365) rs2853815 C or G
                                                      14366 (14365) rs2853815 C or G
                                                      14369 (14368) rs2853816 C or G
                                                      14369 (14368) rs2853816 C or G
                                                      14387 (14386) i3001288 C or T
                                                      14387 (14386) i3001288 C or T
                                                      1440 (1438) rs2001030 A or G
                                                      14413 (14412) i3001289 A or C
                                                      14413 (14412) i3001289 A or C
                                                      14418 (14417) i4001294 A or G
                                                      14418 (14417) i4001294 A or G
                                                      1444 (1442) rs28358573 A or G
                                                      1445 (1443) i3001985 C or T
                                                      14460 (14459) i4001293 A or G
                                                      14460 (14459) i4001293 A or G
                                                      14479 (14478) i4000827 C or T
                                                      14479 (14478) i4000827 C or T
                                                      14489 (14488) i3001293 C or T
                                                      14489 (14488) i3001293 C or T
                                                      14497 (14496) i4000926 A or T
                                                      14497 (14496) i4000926 A or T
                                                      14498 (14497) i3001294 A or G
                                                      14498 (14497) i3001294 A or G
                                                      14503 (14502) i3001296 C or T
                                                      14503 (14502) i3001296 C or T
                                                      14513 (14512) i4001077 C or T
                                                      14513 (14512) i4001077 C or T
                                                      1452 (1450) rs28695305 C or G
                                                      14528 (14527) i3001298 A or T
                                                      14528 (14527) i3001298 A or T
                                                      14531 (14530) i4000925 C or T
                                                      14531 (14530) i4000925 C or T
                                                      14534 (14533) i4000718 C or T
                                                      14534 (14533) i4000718 C or T
                                                      14545 (14544) i3001299 A or G
                                                      14545 (14544) i3001299 A or G
                                                      14553 (14552) i4001291 A or G
                                                      14553 (14552) i4001291 A or G
                                                      14561 (14560) rs28357676 A or G
                                                      14561 (14560) i3001302 C or G
                                                      14561 (14560) rs28357676 A or G
                                                      14561 (14560) i3001302 C or G
                                                      14570 (14569) i3001306 A or G
                                                      14570 (14569) i3001306 A or G
                                                      14578 (14577) i3001307 C or T
                                                      14578 (14577) i3001307 C or T
                                                      14581 (14580) rs28496897 A or G
                                                      14581 (14580) rs28496897 A or G
                                                      14582 (14581) i4000581 C or T
                                                      14582 (14581) i4000581 C or T
                                                      14583 (14582) rs41354845 A or G
                                                      14583 (14582) rs41354845 A or G
                                                      14588 (14587) i3001308 A or G
                                                      14588 (14587) i3001308 A or G
                                                      14621 (14620) i3001309 C or T
                                                      14621 (14620) i3001309 C or T
                                                      14633 (14632) i4000582 C or T
                                                      14633 (14632) i4000582 C or T
                                                      14669 (14668) rs28357678 C or T
                                                      14669 (14668) rs28357678 C or T
                                                      14675 (14674) i3001310 C or T
                                                      14675 (14674) i3001310 C or T
                                                      14688 (14687) i3001311 A or G
                                                      14688 (14687) i3001311 A or G
                                                      14694 (14693) i3001312 A or G
                                                      14694 (14693) i3001312 A or G
                                                      147 (147) i3001880 A or C
                                                      14710 (14709) i4000635 C or T
                                                      14710 (14709) i4000635 C or T
                                                      14728 (14727) i3001315 C or T
                                                      14728 (14727) i3001315 C or T
                                                      14756 (14755) i3001318 A or T
                                                      14756 (14755) i3001318 A or T
                                                      14770 (14769) i3001320 A or G
                                                      14770 (14769) rs28357679 A or G
                                                      14770 (14769) i3001320 A or G
                                                      14770 (14769) rs28357679 A or G
                                                      14775 (14774) i4000624 C or T
                                                      14775 (14774) i4000624 C or T
                                                      14777 (14776) i3001323 A or G
                                                      14777 (14776) i3001323 A or G
                                                      14784 (14783) rs28357680 C or T
                                                      14784 (14783) i3001520 C or T
                                                      14784 (14783) rs28357680 C or T
                                                      14784 (14783) i3001520 C or T
                                                      14794 (14793) i3001325 A or G
                                                      14794 (14793) i3001325 A or G
                                                      14799 (14798) rs28357681 C or T
                                                      14799 (14798) rs28357681 C or T
                                                      14862 (14861) rs2853505 A or G
                                                      14862 (14861) rs2853505 A or G
                                                      14872 (14871) rs28660155 C or T
                                                      14872 (14871) rs28660155 C or T
                                                      14873 (14872) i3001330 C or T
                                                      14873 (14872) i3001330 C or T
                                                      14897 (14896) i3001332 C or G
                                                      14897 (14896) i3001332 C or G
                                                      14903 (14902) i3001333 C or T
                                                      14903 (14902) i3001333 C or T
                                                      14906 (14905) rs28357682 A or G
                                                      14906 (14905) rs28357682 A or G
                                                      1491 (1489) rs28653347 A or G
                                                      14912 (14911) i3001334 C or T
                                                      14912 (14911) i3001334 C or T
                                                      14927 (14926) i3001336 A or G
                                                      14927 (14926) i3001336 A or G
                                                      14928 (14927) i3001337 A or G
                                                      14928 (14927) i3001337 A or G
                                                      14936 (14935) i4000781 C or T
                                                      14936 (14935) i4000781 C or T
                                                      14957 (14956) i4001233 C or T
                                                      14957 (14956) i4001233 C or T
                                                      14979 (14978) i3001339 A or G
                                                      14979 (14978) i3001339 A or G
                                                      14980 (14979) i3001340 C or T
                                                      14980 (14979) i3001340 C or T
                                                      1499 (1497) rs28503725 C or T
                                                      150 (150) i3001901 C or T
                                                      15006 (15005) i4001234 C or G
                                                      15006 (15005) i4001234 C or G
                                                      15008 (15007) i4001235 C or T
                                                      15008 (15007) i4001235 C or T
                                                      15011 (15010) i3001341 A or G
                                                      15011 (15010) i3001341 A or G
                                                      15029 (15028) i3001342 C or T
                                                      15029 (15028) i3001342 C or T
                                                      15041 (15040) i3001343 C or T
                                                      15041 (15040) i3001343 C or T
                                                      15044 (15043) rs28357684 A or G
                                                      15044 (15043) i3001344 C or G
                                                      15044 (15043) rs28357684 A or G
                                                      15044 (15043) i3001344 C or G
                                                      1505 (1503) i4000620 A or G
                                                      15050 (15049) i4001060 C or T
                                                      15050 (15049) i4001060 C or T
                                                      15053 (15052) i3001345 A or G
                                                      15053 (15052) i3001345 A or G
                                                      15062 (15061) i4000516 A or G
                                                      15062 (15061) i4000516 A or G
                                                      15068 (15067) i3001348 C or T
                                                      15068 (15067) i3001348 C or T
                                                      15072 (15071) i3001351 C or T
                                                      15072 (15071) i3001351 C or T
                                                      15081 (15080) i4001161 A or G
                                                      15081 (15080) i4001161 A or G
                                                      15084 (15083) i4001162 C or T
                                                      15084 (15083) i4001162 C or T
                                                      15098 (15097) i3001353 C or T
                                                      15098 (15097) i3001353 C or T
                                                      1510 (1508) i3001986 C or T
                                                      15107 (15106) i3001354 A or G
                                                      15107 (15106) i3001354 A or G
                                                      15111 (15110) rs28357685 A or G
                                                      15111 (15110) rs28357685 A or G
                                                      15116 (15115) rs28357686 C or T
                                                      15116 (15115) rs28357686 C or T
                                                      15137 (15136) rs2854124 C or T
                                                      15137 (15136) rs2854124 C or T
                                                      15179 (15178) i4001065 A or G
                                                      15179 (15178) i4001065 A or G
                                                      15192 (15191) i3001358 C or T
                                                      15192 (15191) i3001358 C or T
                                                      15200 (15199) i3001360 C or T
                                                      15200 (15199) i3001360 C or T
                                                      15209 (15208) i4000975 A or G
                                                      15209 (15208) i4000975 A or G
                                                      15215 (15214) i4000974 C or T
                                                      15215 (15214) i4000974 C or T
                                                      15219 (15218) rs2853506 A or G
                                                      15219 (15218) rs2853506 A or G
                                                      15224 (15223) rs3134742 C or T
                                                      15224 (15223) rs3134742 C or T
                                                      15227 (15226) i3001364 A or G
                                                      15227 (15226) i3001364 A or G
                                                      15228 (15227) i3001365 A or G
                                                      15228 (15227) i3001365 A or G
                                                      15236 (15235) i3001366 A or G
                                                      15236 (15235) i3001366 A or G
                                                      15237 (15236) i3001368 A or G
                                                      15237 (15236) i3001368 A or G
                                                      15245 (15244) rs28357369 A or G
                                                      15245 (15244) i3001521 A or G
                                                      15245 (15244) rs28357369 A or G
                                                      15245 (15244) i3001521 A or G
                                                      15248 (15247) i4001172 C or G
                                                      15248 (15247) i4001172 C or G
                                                      15258 (15257) rs41518645 A or G
                                                      15258 (15257) i3001522 A or G
                                                      15258 (15257) rs41518645 A or G
                                                      15258 (15257) i3001522 A or G
                                                      15259 (15258) i3001370 A or G
                                                      15259 (15258) i3001370 A or G
                                                      1526 (1524) i4001173 A or G
                                                      15262 (15261) i4001103 A or G
                                                      15262 (15261) i4001103 A or G
                                                      15263 (15262) i4001104 C or T
                                                      15263 (15262) i4001104 C or T
                                                      15288 (15287) i3001371 C or T
                                                      15288 (15287) i3001371 C or T
                                                      15290 (15289) i4001106 C or T
                                                      15290 (15289) i4001106 C or T
                                                      153 (153) i3001933 A or G
                                                      15300 (15299) i4001107 C or T
                                                      15300 (15299) i4001107 C or T
                                                      15311 (15310) i4001101 C or T
                                                      15311 (15310) i4001101 C or T
                                                      15312 (15311) rs35070048 A or G
                                                      15312 (15311) rs35070048 A or G
                                                      15313 (15312) i4001102 C or T
                                                      15313 (15312) i4001102 C or T
                                                      15314 (15313) i3001372 A or T
                                                      15314 (15313) i3001372 A or T
                                                      15315 (15314) i3001373 A or G
                                                      15315 (15314) i3001373 A or G
                                                      15318 (15317) rs2853507 A or G
                                                      15318 (15317) rs2853507 A or G
                                                      15324 (15323) i4001108 A or G
                                                      15324 (15323) i4001108 A or G
                                                      15327 (15326) rs2853508 A or G
                                                      15327 (15326) rs2853508 A or G
                                                      15338 (15337) i3001375 C or T
                                                      15338 (15337) i3001375 C or T
                                                      15345 (15344) i4000728 C or T
                                                      15345 (15344) i4000728 C or T
                                                      15346 (15345) i3001376 C or T
                                                      15346 (15345) i3001376 C or T
                                                      15347 (15346) i3001377 A or G
                                                      15347 (15346) i3001377 A or G
                                                      15356 (15355) i3001378 A or G
                                                      15356 (15355) i3001378 A or G
                                                      15359 (15358) i4000730 A or G
                                                      15359 (15358) i4000730 A or G
                                                      15364 (15363) i4000729 A or G
                                                      15364 (15363) i4000729 A or G
                                                      15368 (15367) i3001379 C or T
                                                      15368 (15367) i3001379 C or T
                                                      15389 (15388) i4000879 C or T
                                                      15389 (15388) i4000879 C or T
                                                      1539 (1537) i3001990 C or T
                                                      15395 (15394) i3001381 C or T
                                                      15395 (15394) i3001381 C or T
                                                      15403 (15402) i4000881 C or T
                                                      15403 (15402) i4000881 C or T
                                                      15423 (15422) i3001383 A or G
                                                      15423 (15422) i3001383 A or G
                                                      15432 (15431) rs2853509 A or G
                                                      15432 (15431) rs2853509 A or G
                                                      15441 (15440) i3001384 C or T
                                                      15441 (15440) i3001384 C or T
                                                      15452 (15451) i4000812 C or T
                                                      15452 (15451) i4000812 C or T
                                                      15453 (15452) rs3088309 A or C
                                                      15453 (15452) rs3088309 A or C
                                                      15455 (15454) i3001385 C or T
                                                      15455 (15454) i3001385 C or T
                                                      15459 (15458) i4000810 C or T
                                                      15459 (15458) i4000810 C or T
                                                      15462 (15461) i4000809 C or T
                                                      15462 (15461) i4000809 C or T
                                                      15464 (15463) i3001386 A or G
                                                      15464 (15463) i3001386 A or G
                                                      15467 (15466) i4000811 A or G
                                                      15467 (15466) i4000811 A or G
                                                      15468 (15467) i3001387 A or G
                                                      15468 (15467) i3001387 A or G
                                                      15488 (15487) i3001388 A or T
                                                      15488 (15487) i3001388 A or T
                                                      15498 (15497) i3001389 A or G
                                                      15498 (15497) i3001389 A or G
                                                      15500 (15499) i4000745 C or T
                                                      15500 (15499) i4000745 C or T
                                                      15509 (15508) rs3134743 C or T
                                                      15509 (15508) rs3134743 C or T
                                                      1551 (1549) rs28504042 A or G
                                                      15515 (15514) i3001392 C or T
                                                      15515 (15514) i3001392 C or T
                                                      15520 (15519) i4000746 C or T
                                                      15520 (15519) i4000746 C or T
                                                      15530 (15529) i3001394 A or C
                                                      15530 (15529) i3001394 A or C
                                                      15536 (15535) rs28357371 C or T
                                                      15536 (15535) rs28357371 C or T
                                                      15563 (15562) i3001396 A or G
                                                      15563 (15562) i3001396 A or G
                                                      15590 (15589) i3001397 C or T
                                                      15590 (15589) i3001397 C or T
                                                      156 (156) i4000673 A or G
                                                      15602 (15601) i3001398 C or T
                                                      15602 (15601) i3001398 C or T
                                                      15608 (15607) rs28357372 A or G
                                                      15608 (15607) rs28357372 A or G
                                                      15614 (15613) i4000672 A or G
                                                      15614 (15613) i4000672 A or G
                                                      15618 (15617) i4000671 A or G
                                                      15618 (15617) i4000671 A or G
                                                      15623 (15622) i3001400 C or T
                                                      15623 (15622) i3001400 C or T
                                                      15630 (15629) rs28357373 C or T
                                                      15630 (15629) rs28357373 C or T
                                                      15653 (15652) i4000608 A or G
                                                      15653 (15652) i4000608 A or G
                                                      15662 (15661) i4000607 C or T
                                                      15662 (15661) i4000607 C or T
                                                      15663 (15662) rs3094280 A or G
                                                      15663 (15662) rs3094280 A or G
                                                      15671 (15670) rs28357374 C or T
                                                      15671 (15670) rs28357374 C or T
                                                      15675 (15674) i4000604 C or T
                                                      15675 (15674) i4000604 C or T
                                                      15689 (15688) i4000556 C or T
                                                      15689 (15688) i4000556 C or T
                                                      15694 (15693) i3001404 C or T
                                                      15694 (15693) i3001404 C or T
                                                      15698 (15697) i4000558 C or T
                                                      15698 (15697) i4000558 C or T
                                                      15722 (15721) i4000557 C or T
                                                      15722 (15721) i4000557 C or T
                                                      15725 (15724) i3001405 A or G
                                                      15725 (15724) i3001405 A or G
                                                      15735 (15734) i4000559 A or G
                                                      15735 (15734) i4000559 A or G
                                                      15747 (15746) i3001409 A or G
                                                      15747 (15746) i3001409 A or G
                                                      15748 (15747) i3001410 C or T
                                                      15748 (15747) i3001410 C or T
                                                      15749 (15748) i3001411 C or T
                                                      15749 (15748) i3001411 C or T
                                                      15750 (15749) i4001382 A or C
                                                      15750 (15749) i4001382 A or C
                                                      15755 (15754) i4001381 C or T
                                                      15755 (15754) i4001381 C or T
                                                      15759 (15758) rs41337244 A or G
                                                      15759 (15758) i3001525 A or G
                                                      15759 (15758) rs41337244 A or G
                                                      15759 (15758) i3001525 A or G
                                                      15766 (15765) i3001412 C or G
                                                      15766 (15765) i3001412 C or G
                                                      15776 (15775) i3001414 A or G
                                                      15776 (15775) i3001414 A or G
                                                      15789 (15788) i3001415 A or G
                                                      15789 (15788) i3001415 A or G
                                                      15791 (15790) i3001417 C or T
                                                      15791 (15790) i3001417 C or T
                                                      15794 (15793) i4001323 C or T
                                                      15794 (15793) i4001323 C or T
                                                      15806 (15805) i3001419 A or G
                                                      15806 (15805) i3001419 A or G
                                                      15807 (15806) i4001322 A or G
                                                      15807 (15806) i4001322 A or G
                                                      15813 (15812) i3001420 A or G
                                                      15813 (15812) i3001420 A or G
                                                      15825 (15824) rs28357376 A or G
                                                      15825 (15824) rs28357376 A or G
                                                      15834 (15833) rs41504845 C or T
                                                      15834 (15833) i3001526 C or T
                                                      15834 (15833) rs41504845 C or T
                                                      15834 (15833) i3001526 C or T
                                                      15850 (15849) i4001347 C or T
                                                      15850 (15849) i4001347 C or T
                                                      15851 (15850) i4001345 C or T
                                                      15851 (15850) i4001346 G or T
                                                      15851 (15850) i4001345 C or T
                                                      15851 (15850) i4001346 G or T
                                                      15852 (15851) rs3094281 A or G
                                                      15852 (15851) rs3094281 A or G
                                                      15875 (15874) i3001424 A or G
                                                      15875 (15874) i3001424 A or G
                                                      15878 (15877) i3001425 C or T
                                                      15878 (15877) i3001425 C or T
                                                      15881 (15880) i3001426 A or G
                                                      15881 (15880) i3001426 A or G
                                                      15884 (15883) i3001428 A or G
                                                      15884 (15883) i3001428 A or G
                                                      15885 (15884) rs28617642 A or G
                                                      15885 (15884) rs28617642 A or G
                                                      15890 (15889) i3001430 C or T
                                                      15890 (15889) i3001430 C or T
                                                      15892 (15891) i3001431 C or G
                                                      15892 (15891) i3001431 C or G
                                                      15897 (15896) i4001297 A or G
                                                      15897 (15896) i4001297 A or G
                                                      159 (159) i3001942 C or T
                                                      15901 (15900) i3001432 C or T
                                                      15901 (15900) i3001432 C or T
                                                      15905 (15904) rs35788393 C or T
                                                      15905 (15904) i3001527 C or T
                                                      15905 (15904) rs35788393 C or T
                                                      15905 (15904) i3001527 C or T
                                                      15908 (15907) rs41383248 A or G
                                                      15908 (15907) i3001528 A or G
                                                      15908 (15907) rs41383248 A or G
                                                      15908 (15907) i3001528 A or G
                                                      15914 (15913) i3001433 C or T
                                                      15914 (15913) i3001433 C or T
                                                      15915 (15914) i3001434 A or C
                                                      15915 (15914) i3001434 A or C
                                                      15925 (15924) rs2853510 A or G
                                                      15925 (15924) rs2853510 A or G
                                                      15928 (15927) rs3094282 A or G
                                                      15928 (15927) rs3094282 A or G
                                                      15929 (15928) rs28357377 A or G
                                                      15929 (15928) i3001529 A or G
                                                      15929 (15928) rs28357377 A or G
                                                      15929 (15928) i3001529 A or G
                                                      15931 (15930) rs41441949 A or G
                                                      15931 (15930) i3001530 A or G
                                                      15931 (15930) rs41441949 A or G
                                                      15931 (15930) i3001530 A or G
                                                      15933 (15932) rs28601282 C or T
                                                      15933 (15932) rs28601282 C or T
                                                      15938 (15937) i3001435 A or G
                                                      15938 (15937) i3001435 A or G
                                                      15940 (15939) i4000949 C or T
                                                      15940 (15939) i4000949 C or T
                                                      15941 (15940) i4000948 C or T
                                                      15941 (15940) i4000948 C or T
                                                      15942 (15941) i4000947 C or T
                                                      15942 (15941) i4000947 C or T
                                                      15943 (15942) rs28535186 C or T
                                                      15943 (15942) i3001436 C or T
                                                      15943 (15942) rs28535186 C or T
                                                      15943 (15942) i3001436 C or T
                                                      15947 (15946) i3001440 C or T
                                                      15947 (15946) i3001440 C or T
                                                      15952 (15951) i3001441 A or G
                                                      15952 (15951) i3001441 A or G
                                                      15955 (15954) i3001442 A or C
                                                      15955 (15954) i3001442 A or C
                                                      15969 (15968) i4001001 C or T
                                                      15969 (15968) i4001001 C or T
                                                      15971 (15970) i4001002 C or T
                                                      15971 (15970) i4001002 C or T
                                                      15973 (15972) i4001003 C or T
                                                      15973 (15972) i4001003 C or T
                                                      15979 (15978) i4001000 C or T
                                                      15979 (15978) i4001000 C or T
                                                      1600 (1598) rs3135027 A or G
                                                      16004 (16003) i3001443 C or T
                                                      16004 (16003) i3001443 C or T
                                                      16018 (16017) i3001444 C or T
                                                      16018 (16017) i3001444 C or T
                                                      16026 (16025) i3001543 G or T
                                                      16026 (16025) i3001543 G or T
                                                      16042 (16041) i3001548 A or T
                                                      16042 (16041) i3001548 A or T
                                                      16043 (16042) i3001550 G or T
                                                      16043 (16042) i3001550 G or T
                                                      16049 (16048) i3001551 A or G
                                                      16049 (16048) i3001551 A or G
                                                      16052 (16051) i3001552 A or G
                                                      16052 (16051) i3001552 A or G
                                                      16053 (16052) i4001134 C or T
                                                      16053 (16052) i4001134 C or T
                                                      16060 (16059) i3001553 A or G
                                                      16060 (16059) i3001553 A or G
                                                      16061 (16060) i3001556 G or T
                                                      16061 (16060) i3001556 G or T
                                                      16070 (16069) i3001561 C or T
                                                      16070 (16069) i3001561 C or T
                                                      16074 (16073) i3001564 C or G
                                                      16074 (16073) i3001564 C or G
                                                      16077 (16076) i3001568 C or T
                                                      16077 (16076) i3001568 C or T
                                                      16079 (16078) i4000680 A or T
                                                      16079 (16078) i4000680 A or T
                                                      16084 (16083) i3001572 A or C
                                                      16084 (16083) i3001572 A or C
                                                      16086 (16085) i3001573 C or T
                                                      16086 (16085) i3001573 C or T
                                                      16093 (16092) i3001576 C or T
                                                      16093 (16092) i3001576 C or T
                                                      16094 (16093) i3001578 A or T
                                                      16094 (16093) i3001578 A or T
                                                      16095 (16094) i3001580 G or T
                                                      16095 (16094) i3001580 G or T
                                                      16096 (16095) i3001581 C or T
                                                      16096 (16095) i3001581 C or T
                                                      16098 (16097) i3001582 C or T
                                                      16098 (16097) i3001582 C or T
                                                      16099 (16098) i4000814 A or G
                                                      16099 (16098) i4000814 A or G
                                                      16105 (16104) i3001585 C or T
                                                      16105 (16104) i3001585 C or T
                                                      16112 (16111) i3001593 A or C
                                                      16112 (16111) i3001593 A or C
                                                      16115 (16114) i3001596 C or T
                                                      16115 (16114) i3001596 C or T
                                                      16119 (16118) i3001600 A or G
                                                      16119 (16118) i3001600 A or G
                                                      16121 (16120) i4000538 A or T
                                                      16121 (16120) i4000538 A or T
                                                      16123 (16122) i4000537 A or G
                                                      16123 (16122) i4000537 A or G
                                                      16125 (16124) i3001601 C or T
                                                      16125 (16124) i3001601 C or T
                                                      16127 (16126) i3001603 C or T
                                                      16127 (16126) i3001603 C or T
                                                      1613 (1611) i4000888 A or G
                                                      16130 (16129) rs5005270 A or G
                                                      16130 (16129) i3001605 C or G
                                                      16130 (16129) rs5005270 A or G
                                                      16130 (16129) i3001605 C or G
                                                      16131 (16130) i3001606 A or G
                                                      16131 (16130) i3001606 A or G
                                                      16133 (16132) i3001610 A or T
                                                      16133 (16132) i3001610 A or T
                                                      16134 (16133) i3001611 C or T
                                                      16134 (16133) i3001611 C or T
                                                      16136 (16135) i4000724 A or G
                                                      16136 (16135) i4000724 A or G
                                                      16139 (16138) i3001614 A or G
                                                      16139 (16138) i3001614 A or G
                                                      16141 (16140) rs3134562 C or T
                                                      16141 (16140) rs3134562 C or T
                                                      16143 (16142) i4000725 C or T
                                                      16143 (16142) i4000725 C or T
                                                      16145 (16144) rs41505649 C or T
                                                      16145 (16144) rs41505649 C or T
                                                      16146 (16145) rs41419246 A or G
                                                      16146 (16145) rs41419246 A or G
                                                      16147 (16146) i4000726 A or G
                                                      16147 (16146) i4000726 A or G
                                                      16148 (16147) i4000638 C or T
                                                      16148 (16147) i4000639 C or G
                                                      16148 (16147) i4000727 A or C
                                                      16148 (16147) i4000638 C or T
                                                      16148 (16147) i4000639 C or G
                                                      16148 (16147) i4000727 A or C
                                                      16149 (16148) rs2854125 C or T
                                                      16149 (16148) rs2854125 C or T
                                                      16154 (16153) rs2853512 A or G
                                                      16154 (16153) rs2853512 A or G
                                                      16155 (16154) i4000641 C or T
                                                      16155 (16154) i4000641 C or T
                                                      16156 (16155) i4000640 A or G
                                                      16156 (16155) i4000640 A or G
                                                      16158 (16157) i4001383 C or T
                                                      16158 (16157) i4000643 A or T
                                                      16158 (16157) i4001383 C or T
                                                      16158 (16157) i4000643 A or T
                                                      16159 (16158) i4000848 A or T
                                                      16159 (16158) i4000848 A or T
                                                      16162 (16161) i4000846 C or T
                                                      16162 (16161) i4000846 C or T
                                                      16163 (16162) rs41466049 A or G
                                                      16163 (16162) rs41466049 A or G
                                                      16164 (16163) rs41479950 A or G
                                                      16164 (16163) i4000851 A or G
                                                      16164 (16163) rs41479950 A or G
                                                      16164 (16163) i4000851 A or G
                                                      16165 (16164) i4000849 A or G
                                                      16165 (16164) i4000849 A or G
                                                      16166 (16165) i4000850 A or G
                                                      16166 (16165) i4000850 A or G
                                                      16167 (16166) i4000843 A or C
                                                      16167 (16166) i4000844 A or G
                                                      16167 (16166) i4000843 A or C
                                                      16167 (16166) i4000844 A or G
                                                      16168 (16167) i4000786 C or T
                                                      16168 (16167) i4000786 C or T
                                                      16170 (16169) i4000787 C or T
                                                      16170 (16169) i4000788 A or C
                                                      16170 (16169) i4000787 C or T
                                                      16170 (16169) i4000788 A or C
                                                      16172 (16171) i4000782 A or G
                                                      16172 (16171) i4000782 A or G
                                                      16173 (16172) rs2853817 C or T
                                                      16173 (16172) rs2853817 C or T
                                                      16174 (16173) i4000780 C or T
                                                      16174 (16173) i4000780 C or T
                                                      16175 (16174) i4000779 C or T
                                                      16175 (16174) i4000779 C or T
                                                      16176 (16175) i4001353 A or G
                                                      16176 (16175) i4001353 A or G
                                                      16177 (16176) i4001354 A or C
                                                      16177 (16176) i4001355 C or G
                                                      16177 (16176) i4001356 C or T
                                                      16177 (16176) i4001354 A or C
                                                      16177 (16176) i4001355 C or G
                                                      16177 (16176) i4001356 C or T
                                                      16178 (16177) i4001350 A or G
                                                      16178 (16177) i4001350 A or G
                                                      16183 (16182) i4001307 A or G
                                                      16183 (16182) i4001307 A or G
                                                      16184 () rs28671493 A or C
                                                      16184 () i4001306 A or C
                                                      16184 () i4001305 A or G
                                                      16184 () rs28671493 A or C
                                                      16184 () i4001306 A or C
                                                      16184 () i4001305 A or G
                                                      16186 (16184) rs34100702 C or T
                                                      16186 (16184) rs34100702 C or T
                                                      16187 (16185) i4001304 C or T
                                                      16187 (16185) i4001304 C or T
                                                      16190 (16188) i4000588 A or C
                                                      16190 (16188) i4000586 C or T
                                                      16190 (16188) i4000588 A or C
                                                      16190 (16188) i4000586 C or T
                                                      16194 (16192) i4001097 A or C
                                                      16194 (16192) i4001099 C or T
                                                      16194 (16192) i4001097 A or C
                                                      16194 (16192) i4001099 C or T
                                                      16195 (16193) i4000525 C or G
                                                      16195 (16193) i4000525 C or G
                                                      16197 (16195) i4000529 A or T
                                                      16197 (16195) i4000529 A or T
                                                      16199 (16197) i4000522 C or T
                                                      16199 (16197) i4000522 C or T
                                                      1620 (1618) i3001992 A or G
                                                      16200 (16198) i4001119 C or T
                                                      16200 (16198) i4001119 C or T
                                                      16203 (16201) i4001120 C or T
                                                      16203 (16201) i4001120 C or T
                                                      16205 (16203) i4001121 A or G
                                                      16205 (16203) i4001121 A or G
                                                      16208 (16206) i4001124 A or G
                                                      16208 (16206) i4001123 A or C
                                                      16208 (16206) i4001124 A or G
                                                      16208 (16206) i4001123 A or C
                                                      16209 (16207) i4001117 A or T
                                                      16209 (16207) i4001126 A or G
                                                      16209 (16207) i4001117 A or T
                                                      16209 (16207) i4001126 A or G
                                                      16211 (16209) i4001054 C or T
                                                      16211 (16209) i4001054 C or T
                                                      16214 (16212) i4001052 A or G
                                                      16214 (16212) i4001052 A or G
                                                      16215 (16213) i4001051 A or G
                                                      16215 (16213) i4001051 A or G
                                                      16216 (16214) i4001057 C or T
                                                      16216 (16214) i4001058 A or C
                                                      16216 (16214) i4001057 C or T
                                                      16216 (16214) i4001058 A or C
                                                      16219 (16217) rs35134837 C or T
                                                      16219 (16217) rs35134837 C or T
                                                      16220 (16218) i4000794 C or T
                                                      16220 (16218) i4000795 A or C
                                                      16220 (16218) i4000794 C or T
                                                      16220 (16218) i4000795 A or C
                                                      16224 (16222) i4000800 C or T
                                                      16224 (16222) i4000800 C or T
                                                      16226 (16224) i4000793 C or T
                                                      16226 (16224) i4000793 C or T
                                                      16230 (16228) i4000859 C or T
                                                      16230 (16228) i4000861 C or G
                                                      16230 (16228) i4000859 C or T
                                                      16230 (16228) i4000861 C or G
                                                      16232 (16230) rs2853514 A or G
                                                      16232 (16230) rs2853514 A or G
                                                      16233 (16231) i4000857 C or T
                                                      16233 (16231) i4000857 C or T
                                                      16234 (16232) i4000855 C or T
                                                      16234 (16232) i4000858 A or C
                                                      16234 (16232) i4000855 C or T
                                                      16234 (16232) i4000858 A or C
                                                      16236 (16234) i3001728 C or T
                                                      16236 (16234) i3001728 C or T
                                                      16237 (16235) i3001729 A or G
                                                      16237 (16235) i3001729 A or G
                                                      16239 (16237) i4000661 A or T
                                                      16239 (16237) i4000661 A or T
                                                      16241 (16239) i3001732 C or T
                                                      16241 (16239) i3001732 C or T
                                                      16242 (16240) i3001733 A or G
                                                      16242 (16240) i3001733 A or G
                                                      16243 (16241) i3001735 A or G
                                                      16243 (16241) i3001735 A or G
                                                      16244 (16242) i3001737 C or T
                                                      16244 (16242) i3001737 C or T
                                                      16245 (16243) i3001738 C or T
                                                      16245 (16243) i3001738 C or T
                                                      16246 (16244) i3001739 A or G
                                                      16246 (16244) i3001739 A or G
                                                      16247 (16245) i3001740 C or T
                                                      16247 (16245) i3001740 C or T
                                                      16248 (16246) i3001743 A or T
                                                      16248 (16246) i3001743 A or T
                                                      16250 (16248) i3001745 C or T
                                                      16250 (16248) i3001745 C or T
                                                      16251 (16249) i3001747 C or T
                                                      16251 (16249) i3001747 C or T
                                                      16252 (16250) i3001748 C or T
                                                      16252 (16250) i3001748 C or T
                                                      16254 (16252) i3001750 A or T
                                                      16254 (16252) i3001750 A or T
                                                      16255 (16253) i3001751 A or G
                                                      16255 (16253) i3001751 A or G
                                                      16256 (16254) i3001752 A or G
                                                      16256 (16254) i3001752 A or G
                                                      16257 (16255) i3001753 A or G
                                                      16257 (16255) i3001753 A or G
                                                      16258 (16256) i3001754 C or T
                                                      16258 (16256) i3001754 C or T
                                                      16259 (16257) i3001755 C or T
                                                      16259 (16257) i3001755 C or T
                                                      16260 (16258) i3001759 A or C
                                                      16260 (16258) i3001759 A or C
                                                      16262 (16260) i3001762 C or T
                                                      16262 (16260) i3001762 C or T
                                                      16263 (16261) i3001763 C or T
                                                      16263 (16261) i3001763 C or T
                                                      16265 (16263) i3001767 G or T
                                                      16265 (16263) i3001767 G or T
                                                      16266 (16264) i3001770 C or T
                                                      16266 (16264) i3001770 C or T
                                                      16268 (16266) i3001776 C or T
                                                      16268 (16266) i3001776 C or T
                                                      1627 (1625) rs28633296 A or G
                                                      16270 (16268) i4000983 C or T
                                                      16270 (16268) i4000983 C or T
                                                      16271 (16269) i4000984 A or C
                                                      16271 (16269) i4000984 A or C
                                                      16272 (16270) rs2857290 C or T
                                                      16272 (16270) i3001782 C or T
                                                      16272 (16270) rs2857290 C or T
                                                      16272 (16270) i3001782 C or T
                                                      16273 (16271) i3001537 C or T
                                                      16273 (16271) i3001537 C or T
                                                      16275 (16273) i3001784 A or G
                                                      16275 (16273) i3001784 A or G
                                                      16276 (16274) i3001785 A or G
                                                      16276 (16274) i3001785 A or G
                                                      16277 (16275) i3001787 A or G
                                                      16277 (16275) i3001787 A or G
                                                      16279 (16277) i3001789 A or T
                                                      16279 (16277) i3001789 A or T
                                                      16280 (16278) i3001790 C or T
                                                      16280 (16278) i3001790 C or T
                                                      16281 (16279) i3001538 C or T
                                                      16281 (16279) i3001538 C or T
                                                      16285 (16283) i3001793 A or G
                                                      16285 (16283) i3001793 A or G
                                                      16286 (16284) i3001794 A or G
                                                      16286 (16284) i3001794 A or G
                                                      16288 (16286) i3001796 C or T
                                                      16288 (16286) i3001796 C or T
                                                      16290 (16288) i3001798 C or T
                                                      16290 (16288) i3001798 C or T
                                                      16292 (16290) i3001800 C or T
                                                      16292 (16290) i3001800 C or T
                                                      16293 (16291) i3001801 C or T
                                                      16293 (16291) i3001801 C or T
                                                      16295 (16293) i3001808 A or T
                                                      16295 (16293) i3001808 A or T
                                                      16296 (16294) i3001809 C or T
                                                      16296 (16294) i3001809 C or T
                                                      16297 (16295) i3001810 C or T
                                                      16297 (16295) i3001810 C or T
                                                      16298 (16296) i3001811 C or T
                                                      16298 (16296) i3001811 C or T
                                                      16299 (16297) i3001812 C or T
                                                      16299 (16297) i3001812 C or T
                                                      16300 (16298) i3001813 C or T
                                                      16300 (16298) i3001813 C or T
                                                      16301 (16299) i3001814 A or G
                                                      16301 (16299) i3001814 A or G
                                                      16302 (16300) i3001815 A or G
                                                      16302 (16300) i3001815 A or G
                                                      16303 (16301) i3001816 C or T
                                                      16303 (16301) i3001816 C or T
                                                      16304 (16302) i3001818 A or G
                                                      16304 (16302) i3001818 A or G
                                                      16305 (16303) i3001820 C or G
                                                      16305 (16303) i3001820 C or G
                                                      16307 (16305) i3001823 A or G
                                                      16307 (16305) i3001823 A or G
                                                      16308 (16306) i4001210 C or T
                                                      16308 (16306) i4001209 C or G
                                                      16308 (16306) i4001210 C or T
                                                      16308 (16306) i4001209 C or G
                                                      16310 (16308) i3001824 C or T
                                                      16310 (16308) i3001824 C or T
                                                      16311 (16309) i3001826 A or G
                                                      16311 (16309) i3001826 A or G
                                                      16312 (16310) i3001829 A or G
                                                      16312 (16310) i3001829 A or G
                                                      16313 (16311) rs34799580 C or T
                                                      16313 (16311) rs34799580 C or T
                                                      16314 (16312) i3001830 A or G
                                                      16314 (16312) i3001830 A or G
                                                      16315 (16313) i3001831 C or T
                                                      16315 (16313) i3001831 C or T
                                                      16316 (16314) i3001832 A or G
                                                      16316 (16314) i3001832 A or G
                                                      16318 (16316) i3001833 A or G
                                                      16318 (16316) i3001833 A or G
                                                      16319 (16317) i3001835 A or G
                                                      16319 (16317) i3001835 A or G
                                                      16320 (16318) i3001839 A or T
                                                      16320 (16318) i3001839 A or T
                                                      16321 (16319) i3001840 A or G
                                                      16321 (16319) i3001840 A or G
                                                      16322 (16320) i3001841 C or T
                                                      16322 (16320) i3001841 C or T
                                                      16324 (16322) i3001843 A or G
                                                      16324 (16322) i3001843 A or G
                                                      16325 (16323) i3001844 C or T
                                                      16325 (16323) i3001844 C or T
                                                      16326 (16324) i3001845 C or T
                                                      16326 (16324) i3001845 C or T

                                                      (Message over 64 KB, truncated)
                                                    Your message has been successfully submitted and would be delivered to recipients shortly.