Smaller Doses Of HIV Drugs Could Be Effective, Says Report
- AIDS patients may be able to cut the dose of antiviral drugs they take and
the treatment could be just as effective, says a small US federally funded
If the findings are the same on a large study group it could mean saving
millions on HIV drugs, particularly in developing countries which cannot
afford expensive drugs.
Drug therapy to combat the AIDS virus typically costs between $15,000 and
Mark Dybul, Anthony Fauci and their colleagues at the National Institute
of Allergy and Infectious Diseases looked into whether the AIDS virus
could be kept at bay with a smaller dose of anti-viral drugs
A group of 10 HIV-infected people a cocktail of antiviral drugs of
stavudine, lamivudine, indinavir and ritonavir. The patients got the drugs
for seven days in a row, then discontinued them for seven days. They
repeated that same on-off cycle for up to a year.
The research team found that the on-off- on approach with drugs to combat
HIV appeared to work.
People with HIV should not attempt to follow such a drug regime on their
own, warned the research team. The small group involved in the study were
carefully monitored and under continual medical supervision.