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Single Test for HIV, HBV, HCV in Donor Blood

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  • claudine intexas
    Single Test for Hiv, Hbv, Hcv in Donor Blood Novenber 29, 2001 Single Test for HIV, HBV, HCV in Donor Blood A new single nucleic acid amplification test (NAT)
    Message 1 of 1 , Dec 5, 2001
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      Single Test for Hiv, Hbv, Hcv in Donor Blood
      Novenber 29, 2001

      Single Test for HIV, HBV, HCV in Donor Blood

      A new single nucleic acid amplification test (NAT)
      that could
      simultaneously detect HIV-1, the hepatitis B virus
      (HBV), and/or the hepatitis C
      virus (HCV) in donated blood was introduced at the
      annual meeting of
      the American Association of Blood Banks in San Antonio
      (TX, USA).

      The test, called the Triplex Assay, utilizes the
      transcription mediated
      amplification (TMA) technology of Gen-Probe Inc. (San
      Diego, CA, USA)
      to amplify and detect three viral targets--including
      one DNA and two RNA
      viruses--without compromising the sensitivity for any
      single target.
      The assay is being co-developed by Gen-Probe and
      Chiron Corp (Emeryville,
      CA, USA).

      A study conducted by a contract research company in
      collaboration with
      researchers at prominent medical centers found that
      the addition of
      minipool nucleic acid testing (MP NAT) for HIV-1, HBV,
      and HCV to current
      screening techniques was cost-effective compared to
      other preventive
      interventions and the need for a zero tolerance level
      for infections from
      blood donations.

      "These studies show potential feasibility that not
      only can we screen
      for three of the most common--and potentially
      devastating--bloodborne
      viruses in a single test, but that it may be possible
      to achieve this
      incremental measure of safety without sacrificing
      sensitivity or
      specificity, the two cornerstones of any successful
      test," said Larry Mimms,
      vice president of development at Gen-Probe.

      By medinews.com staff writers: 21/10/2001 Related
      Links:
      Gen-ProbeChiron

      To see more of Medinews.com, or to subscribe, go to
      http://www.medinews.com



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