[Clinical aspects, course and extrahepatic manifestations of hepatitis C.]
- Wien Med Wochenschr 2000;150(23-24):467-71
[Clinical aspects, course and extrahepatic
manifestations of hepatitis C.]
[Article in German]
Hartmann G, Ben Ramadar EB, Hubl G, Sebesta C.
2. Medizinische Abteilung des Donauspitals im SMZ-Ost
der Stadt Wien, Langobardenstrasse 122, A-1220 Wien.
Hepatitis C virus infection occasionally causes acute
icteric hepatitis. However, primary infection is
usually asymptomatic. Viral clearance occurs only in
20%; most patients develop a chronic hepatitis, which
tends to be hardly symptomatic for many years. The
risk of progression to cirrhosis, hepatocellular
carcinoma and end-stage liver disease is associated
with the severity of histopathological changes, and is
increased by additional factors, such as excessive
alcohol intake or coinfection with hepatitis B virus
and HIV. Immunologically mediated extrahepatic
manifestations of hepatitis C, in particular essential
mixed cryoglobulinemia, can often be observed.
Occasionally, they lead to fatal complications.
PMID: 11205176 [PubMed - indexed for MEDLINE]
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