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Re: [GIWorld-Hepatitis] Re: to Doc: INFO: Triple therapy for non-responders

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  • Doc
    Claudine, I havent checked that out, it maybe daily or alternate day or with peg..all the same. No definite guidelines yet as the studies are too few. Each
    Message 1 of 4 , Mar 1, 2001
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      Claudine,
      I havent checked that out, it maybe daily or alternate day or with peg..all the same. No definite
      guidelines yet as the studies are too few. Each trial wants to be different so it can get published
      , its the world of publish or perish!

      Dr Sharat C Misra MD, DM
      ----- Original Message -----
      From: claudine intexas
      To: GIWorld-Hepatitis@yahoogroups.com
      Sent: Thursday, March 01, 2001 11:47 PM
      Subject: [GIWorld-Hepatitis] Re: to Doc: INFO: Triple therapy for non-responders


      Hi Doc,
      If I'm reading, and adding right, this study
      mentions a total of 4 studies (or abstracts) on triple
      therapy in non-responders. I have one of these, and
      in that one the dosing of interferon was 5mu every
      other day. Would you happen to know the dosing of
      interferon in the other studies? I don't suppose it's
      that important, I am just curious. My doctor is
      currently participating in a study of triple therapy
      but with daily dosing of interferon, but he wants me
      to wait and do triple therapy with a pegylated
      interferon.
      Claudine

      --- Doc <gidoctor@...> wrote:
      > First There Was One, Then Two, Now Three?
      > T. M. McCashland, M.D.

      > Brillanti S, Levantesi F, Masi L, et al. Triple
      > antiviral therapy as a new option for patients
      > with interferon nonresponsive chronic hepatitis C.
      > Hepatology 2000;32:630-4.

      > Three abstracts (Hepatology 2000;32:768A, 770A,
      > 1140A) also describe a higher response rate
      > (15-43%) with triple therapy than combination
      > therapy in initial nonresponders.


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