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Fibrosis Improved With Hepatitis C Vaccine, Innogenetics Reports

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    Fibrosis Improved With Hepatitis C Vaccine, Innogenetics Reports BRUSSELS (Reuters) Mar 25 - Belgian biotech company Innogenetics said on Thursday that
    Message 1 of 1 , Mar 30, 2004
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      Fibrosis Improved With Hepatitis C Vaccine, Innogenetics Reports

      BRUSSELS (Reuters) Mar 25 - Belgian biotech company Innogenetics said
      on Thursday that patients given its hepatitis C experimental vaccine
      showed significantly improved liver fibrosis after a 3-year test
      period.

      Innogenetics said in a statement that "liver fibrosis on average
      showed significant improvement compared to baseline" in 23 patients
      over a three-year period after four course of vaccine injections.

      Eighty-seven percent of the patients either improved or remained
      stable in the liver fibrosis score.

      The company, which also develops test kits for such viruses as HIV,
      already reported positive results in October 2002 based on two
      vaccination courses followed by liver biopsy.

      "These three-year study results now show that HCV E1 vaccination was
      very well tolerated and suggest that such treatment not only halts
      disease progression towards liver cirrhosis, but also results in
      fibrosis regression over the longer term," Professor F. Nevens, the
      principal investigator in the phase IIa clinical study, said in a
      statement.



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