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Antimicrobial Strategies for Preventing Infections in Transplant.htm

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    Antimicrobial Strategies for Preventing Infections in Transplant Focus On... ADHD ALLHAT Alzheimer s Disease APN Business & Law Asthma Biologic Therapies
    Message 1 of 1 , Jun 24, 2003
      Antimicrobial Strategies for Preventing Infections in Transplant

      Focus On... ADHD ALLHAT Alzheimer's Disease APN Business & Law Asthma Biologic Therapies Bioterrorism Bipolar Disorder Breast Cancer Depression Erectile Dysfunction Genital Herpes GERD Geriatric Care Heart Failure Heart Failure: CRT Hepatitis C HIPAA Home Defib in SCA Hyperlipidemia IBS InfluenZone Insulin Pump Tx Kidney Disease Lung Cancer Menopause Micro Complications Multiple Sclerosis Nutrition Osteoporosis Ovarian Cancer Pain Management Pancreatic Cancer Patient Safety Rheum Arthritis Schizophrenia Secondary Anemia Sepsis Serious Mental Ill Sports Medicine UTI-Zone Weight Management ================= Related Topics ================= Disaster & Trauma Dyslipidemia & HIV Health Diversity Hospice Care

      Welcome, A Hauldren

      June 24, 2003

      In This Article
      Abstract and Introduction
      Fungal Infections
      Viral Infections
      Bacterial Infections



      Review Article
      Antimicrobial Strategies for the Prevention of Infections in Liver Transplant Recipients

      from Abstracts in Hematology & OncologyTM
      Posted 06/23/2003
      Nina Singh, MD

      Abstract and Introduction
      Within the last decade, resistance to antimicrobial agents among opportunistic pathogens in transplant recipients has increased dramatically. Emergence of azole resistance in Candida species and the increase of infections with non-albicans Candida species are of concern in liver transplant recipients. An optimal prophylaxis for cytomegalovirus (CMV) disease in transplant recipients remains controversial. A worrisome observation is the increase in ganciclovir-resistant CMV infections in transplant recipients. Staphylococcus aureus is increasingly recognized as a virulent pathogen. In all cases, the value of prophylaxis must be balanced against the need to avoid overprescribing antimicrobials.

      The spectrum of major infections occurring after transplantation has undergone a striking evolution. While a number of opportunistic infections, such as those from cytomegalovirus (CMV) and Pneumocystis carinii, have decreased, infections caused by antimicrobial-resistant bacteria have increased.[1,2] Multidrug-resistant bacteria have now emerged as significant pathogens at many transplant centers, and management of infections caused by these bacteria has proved particularly challenging. This article reviews antimicrobial prophylaxis of infections after liver transplantation in the context of emerging trends in major infections in these patients.


      Section 1 of 4

      Nina Singh, MD, University of Pittsburgh School of Medicine and Pittsburgh Veterans Affairs Medical Center, Thomas E. Starzl Transplantation Institute

      Abstr Hematol Oncol 6(2):19-26, 2003. � 2003 Cliggott Publishing, Division of SCP Communications

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