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Magnesium Load Test Finds Depletion in Patients With Liver Cirrhosis

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  • claudine intexas
    DGReview Magnesium Load Test Finds Depletion in Patients With Liver Cirrhosis A DGReview of : Magnesium depletion in chronic terminal liver cirrhosis.
    Message 1 of 1 , Sep 25, 2002
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      DGReview


      Magnesium Load Test Finds Depletion in Patients With Liver Cirrhosis
      A DGReview of :"Magnesium depletion in chronic terminal liver
      cirrhosis."
      Clinical Transplantation

      09/17/2002
      By Mark Moran


      Chronic terminal cirrhotics may be magnesium depleted, a factor that
      should be considered in cases of liver transplantation and other
      interventions.

      However, spot serum ionized magnesium reveals depletion poorly, say
      researchers at Helsinki University Hospital, Helsinki, Finland.

      They say the most reliable method for evaluating magnesium status is
      the magnesium loading test. In cases of depletion, uptake of
      magnesium is increased by 20-50 percent reaching a level of 6 percent
      of normal magnesium status; normally, it represents less than one
      percent of the total body magnesium.

      Ten chronic cirrhotics listed for liver transplantation and six
      healthy controls were tested for magnesium loading using an infusion
      of 30 mmol magnesium sulphate. Urine magnesium was determined over 24
      hours.

      The researchers found that there was no difference in serum ionized
      magnesium. The loading test, however, found that uptake was 34 � 26
      percent in the cirrhotic patients, compared to 8 � 8 percent in the
      control patents.
      Clin Transplant 2002 Oct;16(5):325-8 "Magnesium depletion in chronic
      terminal liver cirrhosis."


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