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Hep C & Pregnancy: risks for transmission

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  • claudine intexas
    NATAP - www.natap.org Hep C & Pregnancy: risks for transmission http://www.natap.org/2001/ddw/ddw_17pregnancy080101 This subject has not been well studied so
    Message 1 of 1 , Sep 18, 2002
      NATAP - www.natap.org

      Hep C & Pregnancy: risks for transmission
      http://www.natap.org/2001/ddw/ddw_17pregnancy080101

      This subject has not been well studied so we do not have clear
      answers
      to
      many of these questions, but here are key published studies providing

      helpful
      information. Studies find HIV increases risk for HCV transmission by
      about
      3-5 times. A high HCV viral load in pregnant woman can increase risk.

      This
      articles discusses rates of transmission found in studies conducted
      and
      various risk factors and possible ways to reduce risk: c-section
      experiences.
      The extent of maternal-fetal blood exchange at time of delivery may
      be
      the
      major determinant of transmission as suggested by the duration of
      membrane
      rupture

      Mother-to-Infant Transmission of Hepatitis C Virus
      http://www.natap.org/2001/sep/mother_to_infant091401.htm

      This article is a comprehensive review of 77 found published articles

      on the
      topic of risk factors for transmission & the rates for transmission.
      Rates
      for transmission are very variable from study to study but on average

      appear
      to be 5-7%. Risk for tranmission may be a bit higher in IVDUs perhaps

      due to
      higher HCV viral load. Studies suggest above (10 to the 5th) 100,000
      or
      (10
      to the 6th) 1 million may be a level at which risk increases
      significantly.
      Risk may increase as viral load increases. Although its not clear
      breastfeeding could present a ris, this is discussed in article.

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