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Alpha Lipoic Acid: The Natural Anti-Inflammatory

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  • yogiguruji
    Good Morning! Alpha Lipoic Acid: The Natural Anti-Inflammatory Unlike Vitamin C, which is water soluble and Vitamin E, which is fat soluble, Alpha Lipoic Acid
    Message 1 of 10 , Dec 9 7:01 AM
      Good Morning!

      Alpha Lipoic Acid: The Natural Anti-Inflammatory

      Unlike Vitamin C, which is water soluble and Vitamin E, which is fat
      soluble, Alpha Lipoic Acid is a unique antioxidant that is both water
      and fat soluble, which allows it to enter all parts of the cell to
      neutralize free radicals. Alpha Lipoic Acid contributes to and is
      important for the production of energy inside the cell by utilizing
      sugar to produce energy contributing to mental and physical stamina,
      reducing muscle fatigue and neutralizes free radicals. Alpha Lipoic
      Acid recycles and enhances the effects of both Vitamin C and Vitamin
      E.

      Scientists first discovered the importance of alpha lipoic acid in
      the 1950s, and recognized it as an antioxidant in 1988. It has been
      the subject of research around the world, some being done at UC
      Berkeley by Dr. Lester Packer, a leading expert in the area of
      antioxidants and a professor of molecular and cell biology at the
      University of California at Berkeley. He believes that Alpha Lipoic
      Acid could have far-reaching consequences in the search for
      prevention and therapy of chronic degenerative diseases such as
      diabetes and cardiovascular disease. Because it's the only
      antioxidant that can easily get into the brain, it could be useful in
      preventing oxidative stress and damage from a stroke. [1].

      Alpha Lipoic Acid is easily absorbed when taken orally and once
      inside cells is quickly converted to its most potent form,
      dihydrolipoic acid. Because both Alpha Lipoic Acid and dihydrolipoic
      acid are antioxidants, their combined actions give them greater
      antioxidant potency than any natural antioxidant now known. This also
      makes it important for regulating aspects of the immune system, in
      particular, T-lymphocytes. [2].

      The incidence of inflammatory diseases such as arthritis increases
      with age. Free radicals promote inflammatory reactions, which
      antioxidants have been successful at diminishing.

      Scientists recently stimulated the inflammatory response of white
      blood cells, resulting in an increase of Intracellular Adhesion
      Molecule 1 (ICAM-1), which encourages white blood cells to stick to
      other cells, thereby inflaming tissues. Alpha-lipoic acid, a potent
      antioxidant, was then added to the mix. Researchers said the acid
      reduced the activity of ICAM-1 to levels in normal, un-stimulated
      cells in a dose-dependent manner. It also lowered the activity of
      NFkB. According to the study, these changes suggest that alpha-lipoic
      acid may help reduce the effects of inflammatory diseases such a
      rheumatoid arthritis and psoriasis. [3].

      Suggested dosage for Alpha Lipoic Acid is 100-200 mg in divided doses
      daily.

      SIDE EFFECTS: with alpha lipoic acid are rare but can include:

      • Skin rash and the potential of hypoglycemia in diabetic patients.
      • People who may be deficient in vitamin B1 (such as alcoholics)
      should take vitamin B1 along with alpha lipoic acid supplements.
      • Chronic administration of alpha lipoic acid in animals has
      interfered with the actions of the vitamin, biotin. Whether this has
      significance for humans remains unknown.11A.


      Andrew Pacholyk, MS, L.Ac.
      http://www.peacefulmind.com/anti-aging.htm
      Therapies for healing
      mind, body, spirit


      References:

      1. Farr SA, Poon HF, Dogrukol-Ak D, Drake J, Banks WA, Eyerman E,
      Butterfield DA, Morley JE. "The antioxidants alpha-lipoic acid and N-
      acetylcysteine reverse memory impairment and brain oxidative stress
      in aged SAMP8 mice." Geriatric Research Education and Clinical Center
      (GRECC), VA Medical Center (151/JC), 915 N. Grand Boulevard, St.
      Louis, MO 63109, USA.

      2. Moini H, Packer L, Saris NE. Antioxidant and pro-oxidant
      activities of alpha-lipoic acid and dihydrolipoic acid. Toxicol Appl
      Pharmacol 2002 Jul 182:84-90


      3. Lopez-Burillo S, Tan DX, Mayo JC, Sainz RM, Manchester LC, Reiter
      RJ. Melatonin, xanthurenic acid, resveratrol, EGCG, vitamin C and
      alpha-lipoic acid differentially reduce oxidative DNA damage induced
      by Fenton reagents: a study of their individual and synergistic
      actions. Department of Biochemistry, Molecular Biology and
      Physiology, School of Medicine, University of Valladolid, Valladolid,
      Spain. 2001
    • yogiguruji
      Good Morning! Alpha Lipoic Acid: The Natural Anti-Inflammatory Unlike Vitamin C, which is water soluble and Vitamin E, which is fat soluble, Alpha Lipoic Acid
      Message 2 of 10 , Dec 6 2:55 PM
        Good Morning!

        Alpha Lipoic Acid: The Natural Anti-Inflammatory

        Unlike Vitamin C, which is water soluble and Vitamin E, which is fat soluble, Alpha Lipoic Acid is a unique antioxidant that is both water and fat soluble, which allows it to enter all parts of the cell to neutralize free radicals. Alpha Lipoic Acid contributes to and is important for the production of energy inside the cell by utilizing sugar to produce energy contributing to mental and physical stamina, reducing muscle fatigue and neutralizes free radicals. Alpha Lipoic Acid recycles and enhances the effects of both Vitamin C and Vitamin E.

        Scientists first discovered the importance of alpha lipoic acid in the 1950s, and recognized it as an antioxidant in 1988. It has been the subject of research around the world, some being done at UC Berkeley by Dr. Lester Packer, a leading expert in the area of antioxidants and a professor of molecular and cell biology at the University of California at Berkeley. He believes that Alpha Lipoic Acid could have far-reaching consequences in the search for prevention and therapy of chronic degenerative diseases such as diabetes and cardiovascular disease. Because it's the only antioxidant that can easily get into the brain, it could be useful in preventing oxidative stress and damage from a stroke. [21].

        Alpha Lipoic Acid is easily absorbed when taken orally and once inside cells is quickly converted to its most potent form, dihydrolipoic acid. Because both Alpha Lipoic Acid and dihydrolipoic acid are antioxidants, their combined actions give them greater antioxidant potency than any natural antioxidant now known. This also makes it important for regulating aspects of the immune system, in particular, T-lymphocytes. [22].

        The incidence of inflammatory diseases such as arthritis increases with age. Free radicals promote inflammatory reactions, which antioxidants have been successful at diminishing.

        Scientists recently stimulated the inflammatory response of white blood cells, resulting in an increase of Intracellular Adhesion Molecule 1 (ICAM-1), which encourages white blood cells to stick to other cells, thereby inflaming tissues. Alpha-lipoic acid, a potent antioxidant, was then added to the mix. Researchers said the acid reduced the activity of ICAM-1 to levels in normal, un-stimulated cells in a dose-dependent manner. It also lowered the activity of NFkB. According to the study, these changes suggest that alpha-lipoic acid may help reduce the effects of inflammatory diseases such a rheumatoid arthritis and psoriasis. [23].

        Suggested dosage for Alpha Lipoic Acid is 100-200 mg in divided doses daily.

        SIDE EFFECTS: with alpha lipoic acid are rare but can include:

        • Skin rash and the potential of hypoglycemia in diabetic patients.
        • People who may be deficient in vitamin B1 (such as alcoholics) should take vitamin B1 along with alpha lipoic acid supplements.
        • Chronic administration of alpha lipoic acid in animals has interfered with the actions of the vitamin, biotin. Whether this has significance for humans remains unknown.11A.


        Andrew Pacholyk, MS. L.Ac
        http://www.peacefulmind.com/anti-aging.htm
        Therapies for healing
        mind, body, spirit
      • Ieneke van Houten
        Dear Andrew, Could you tell us which whole foods contain Alpha Lipoic Acid? The article was so positive that I almost decided to make an exception to my
        Message 3 of 10 , Dec 7 5:58 PM
          Dear Andrew,

          Could you tell us which whole foods contain Alpha Lipoic Acid?
          The article was so positive that I almost decided to make an exception to my get-it-from-food rule, but then one comes to the end with the usual caveats.

          I have started to think of individual nutrients as a benign kind of drug. Definitely preferable to drug-drugs, and I would not hesitate to use them for a short period.
          But they are still not the same as food.

          Ien in the Kootenays, who will have the very last of the Brussels sprouts from the garden for dinner, with home-grown potatoes and wild pink salmon.
          Yummy and just bursting with all sorts of vitamins, minerals, essential fatty acids etc.

          http://freegreenliving.com
          http://wildwholefoods.net



          [Non-text portions of this message have been removed]
        • yogiguruji
          Hi Ien, Thanks for your post. I hope you are well. Alpha Lipoic Acid is produced in the body, but if you wish to supplement with foods sources red meat is the
          Message 4 of 10 , Dec 7 7:37 PM
            Hi Ien,

            Thanks for your post. I hope you are well.

            Alpha Lipoic Acid is produced in the body, but if you wish to supplement with foods sources red meat is the best source particularly liver and yeast are good whole-foods sources of alpha lipoic acid.

            I hope this helps.


            Blessings,

            Andrew Pacholyk, MS, L.Ac
            http://www.peacefulmind.com
            Therapies for healing
            mind, body,spirit





            --- In AlternativeAnswers@yahoogroups.com, "Ieneke van Houten" <ienvan@...> wrote:
            >
            > Dear Andrew,
            >
            > Could you tell us which whole foods contain Alpha Lipoic Acid?
            > The article was so positive that I almost decided to make an exception to my get-it-from-food rule, but then one comes to the end with the usual caveats.
            >
            > I have started to think of individual nutrients as a benign kind of drug. Definitely preferable to drug-drugs, and I would not hesitate to use them for a short period.
            > But they are still not the same as food.
            >
            > Ien in the Kootenays, who will have the very last of the Brussels sprouts from the garden for dinner, with home-grown potatoes and wild pink salmon.
            > Yummy and just bursting with all sorts of vitamins, minerals, essential fatty acids etc.
            >
            > http://freegreenliving.com
            > http://wildwholefoods.net
            >
            >
            >
            > [Non-text portions of this message have been removed]
            >
          • Ieneke van Houten
            Andrew wrote: Thanks for your post. I hope you are well. Thanks, I m great! No aches or pains and plenty of energy. Andrew wrote: Alpha Lipoic Acid is
            Message 5 of 10 , Dec 7 10:06 PM
              Andrew wrote:

              "Thanks for your post. I hope you are well."

              Thanks, I'm great! No aches or pains and plenty of energy.

              Andrew wrote:

              "Alpha Lipoic Acid is produced in the body, "

              Aha! So the question becomes: what are the precursors?
              What does the body need to make ALA?

              We only eat red meat about twice a month, and pure liver
              is too hard to come by. Yeast, one could do but I hate it.

              Ien in the Kootenays
              http://freegreenliving.com
              http://wildwholefoods.net




              [Non-text portions of this message have been removed]
            • Bussman Karin
              First I want to thank you for your posts. I always look forward to reading them and exploring for more information. Ran out today to get the ALA. My husband
              Message 6 of 10 , Dec 9 8:05 AM
                First I want to thank you for your posts. I always look forward to reading them and exploring for more information.

                Ran out today to get the ALA. My husband suffers from undiagnosed neuropathy in both his feet. Went to many specialists and the only real answer we got was it might be due to a embedded virus that he may have gotten years ago. I hope the ALA helps even a bit because I would like to see him get off Neurontin. I have gotten him to go to acupuncture which seems to help but not on it's own. I have him also on Liquid Kelp which seems to relieve some discomfort.

                Thanks again,
                Karin




                [Non-text portions of this message have been removed]
              • yogiguruji
                Good morning, Karin, Thank you for your wonderful post. I appreciate that very much. It is a great pleasure for me to share information. As an acupuncturist,
                Message 7 of 10 , Dec 10 7:38 AM
                  Good morning, Karin,

                  Thank you for your wonderful post.

                  I appreciate that very much. It is a great pleasure for me to share information.

                  As an acupuncturist, myself, who treats neuropathy on a daily basis, I would suggest to your acupuncturist to use e-stim. Electrostimulation is a process where small electrodes are connected to several of the inserted acupuncture needles. Variation of the current and pulse for 20 minutes over 4 weeks time has shown to stop this neuropathy. The contraindications for e-stim would be if the patient has a history of epilepsy (self or in the family) or if the patient has a pace maker. Otherwise, this is the best treatment for this issue.

                  In the next post, I will post an article about nerve pain and some natural remedy you may consider, if you haven't already.

                  This issue takes time to heal naturally, but with persistence, it will pay off!

                  In happiness,

                  Andrew Pacholyk, MS, L.Ac
                  Peacefulmind.com
                  Therapies for healing
                  mind, body, spirit


                  --- In AlternativeAnswers@yahoogroups.com, Bussman Karin <kbussman@...> wrote:
                  >
                  > First I want to thank you for your posts. I always look forward to reading them and exploring for more information.
                  >
                  > Ran out today to get the ALA. My husband suffers from undiagnosed neuropathy in both his feet. Went to many specialists and the only real answer we got was it might be due to a embedded virus that he may have gotten years ago. I hope the ALA helps even a bit because I would like to see him get off Neurontin. I have gotten him to go to acupuncture which seems to help but not on it's own. I have him also on Liquid Kelp which seems to relieve some discomfort.
                  >
                  > Thanks again,
                  > Karin
                • P.J.Joseph
                  Flax seed is the best alternative to ALA tablets. One tablespoon of grounded flax seed in the morning and evening gives a good supply of ALA. P.J.
                  Message 8 of 10 , Dec 11 6:53 PM
                    Flax seed is the best alternative to ALA tablets. One tablespoon of grounded
                    flax seed in the morning and evening gives a good supply of ALA.
                    P.J.
                  • GOFUR MIAH
                    Mr. Andrew, Thanks for the message. I shall wait for your next letter on nerve pain. A. GOFUR MIAH Dhaka, Bangladesh. ________________________________ From:
                    Message 9 of 10 , Dec 11 10:51 PM
                      Mr. Andrew,
                      Thanks for the message. I shall wait for your next letter on nerve pain.
                      A. GOFUR MIAH
                      Dhaka, Bangladesh.




                      ________________________________
                      From: yogiguruji <yogiguruji@...>
                      To: AlternativeAnswers@yahoogroups.com
                      Sent: Thu, December 10, 2009 9:38:04 PM
                      Subject: [AlternativeAnswers] Re: Alpha Lipoic Acid - Thank you Yogiguruji

                       
                      Good morning, Karin,

                      Thank you for your wonderful post.

                      I appreciate that very much. It is a great pleasure for me to share information.

                      As an acupuncturist, myself, who treats neuropathy on a daily basis, I would suggest to your acupuncturist to use e-stim. Electrostimulation is a process where small electrodes are connected to several of the inserted acupuncture needles. Variation of the current and pulse for 20 minutes over 4 weeks time has shown to stop this neuropathy. The contraindications for e-stim would be if the patient has a history of epilepsy (self or in the family) or if the patient has a pace maker. Otherwise, this is the best treatment for this issue.

                      In the next post, I will post an article about nerve pain and some natural remedy you may consider, if you haven't already.

                      This issue takes time to heal naturally, but with persistence, it will pay off!

                      In happiness,

                      Andrew Pacholyk, MS, L.Ac
                      Peacefulmind. com
                      Therapies for healing
                      mind, body, spirit

                      --- In AlternativeAnswers@ yahoogroups. com, Bussman Karin <kbussman@.. .> wrote:
                      >
                      > First I want to thank you for your posts. I always look forward to reading them and exploring for more information.
                      >
                      > Ran out today to get the ALA. My husband suffers from undiagnosed neuropathy in both his feet. Went to many specialists and the only real answer we got was it might be due to a embedded virus that he may have gotten years ago. I hope the ALA helps even a bit because I would like to see him get off Neurontin. I have gotten him to go to acupuncture which seems to help but not on it's own. I have him also on Liquid Kelp which seems to relieve some discomfort.
                      >
                      > Thanks again,
                      > Karin








                      [Non-text portions of this message have been removed]
                    • Andrew Pacholyk
                      Good Morning! Alpha Lipoic Acid: The Natural Anti-Inflammatory Unlike Vitamin C, which is water soluble and Vitamin E, which is fat soluble, Alpha Lipoic Acid
                      Message 10 of 10 , Jun 29, 2011
                        Good Morning!

                        Alpha Lipoic Acid: The Natural Anti-Inflammatory

                        Unlike Vitamin C, which is water soluble and Vitamin E, which is fat soluble, Alpha Lipoic Acid is a unique antioxidant that is both water and fat soluble, which allows it to enter all parts of the cell to neutralize free radicals. Alpha Lipoic Acid contributes to and is important for the production of energy inside the cell by utilizing sugar to produce energy contributing to mental and physical stamina, reducing muscle fatigue and neutralizes free radicals. Alpha Lipoic Acid recycles and enhances the effects of both Vitamin C and Vitamin E.

                        Scientists first discovered the importance of alpha lipoic acid in the 1950s, and recognized it as an antioxidant in 1988. It has been the subject of research around the world, some being done at UC Berkeley by Dr. Lester Packer, a leading expert in the area of antioxidants and a professor of molecular and cell biology at the University of California at Berkeley. He believes that Alpha Lipoic Acid could have far-reaching consequences in the search for prevention and therapy of chronic degenerative diseases such as diabetes and cardiovascular disease. Because it is the only antioxidant that can easily get into the brain, it could be useful in preventing oxidative stress and damage from a stroke. [21].

                        Alpha Lipoic Acid is easily absorbed when taken orally and once inside cells is quickly converted to its most potent form, dihydrolipoic acid. Because both Alpha Lipoic Acid and dihydrolipoic acid are antioxidants, their combined actions give them greater antioxidant potency than any natural antioxidant now known. This also makes it important for regulating aspects of the immune system, in particular, T-lymphocytes. [22].

                        The incidence of inflammatory diseases such as arthritis increases with age. Free radicals promote inflammatory reactions, which antioxidants have been successful at diminishing.

                        Scientists recently stimulated the inflammatory response of white blood cells, resulting in an increase of Intracellular Adhesion Molecule 1 (ICAM-1), which encourages white blood cells to stick to other cells, thereby inflaming tissues. Alpha-lipoic acid, a potent antioxidant, was then added to the mix. Researchers said the acid reduced the activity of ICAM-1 to levels in normal, un-stimulated cells in a dose-dependent manner. It also lowered the activity of NFkB. According to the study, these changes suggest that alpha-lipoic acid may help reduce the effects of inflammatory diseases such a rheumatoid arthritis and psoriasis. [23].

                        Suggested dosage for Alpha Lipoic Acid is 100-200 mg in divided doses daily.

                        SIDE EFFECTS: with alpha lipoic acid are rare but can include:

                        - Skin rash and the potential of hypoglycemia in diabetic patients.
                        - People who may be deficient in vitamin B1 (such as alcoholics) should take vitamin B1 along with alpha lipoic acid supplements.
                        - Chronic administration of alpha lipoic acid in animals has interfered with the actions of the vitamin, biotin. Whether this has significance for humans remains unknown.11A.


                        Andrew Pacholyk, MS L.Ac
                        http://www.peacefulmind.com/anti-aging.htm
                        Therapies for healing
                        mind, body, spirit
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