I would choose these three from the list as 15 year Grand Challenges.
They all appear to be fairly related compared with the others, so their
union I guess would be my ultimate Grand Challenge.
4. Scalable Ubiquitous Computing Systems
The challenge of the project is to establish design principles working
on a 'build and learn' principle.
6. Dependable Systems Evolution
The project aims to establish a scientific foundation to build systems
whose dependability can be justified, even when it is faced with the
most extreme threats.
7. Journeys in Non-Classical Computing
Working on the basis that biology can operate accurately and safely in
an open, changing environment, the project will seek to mimic that with