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#31 From: "John de Rivaz" <John@...>
Date: Wed Jul 14, 2004 4:49 pm
Subject: Long Life vol 3 no 6 - Immortalist Highlights July-August 4004
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Long Life: the Cryonics Institute newsletter

July 2004 -- Volume 3, Number 6 - Immortalist Highlights

Welcome to Long Life -- the electronic newsletter of the Cryonics Institute. We're here to update you with brief cutting-edge news, updates, links, and information about the latest scientific, medical, health, anti-ageing, and social developments relevant to CI's goal of saving, preserving, and extending human life. Long Life may also include news about Cryonics Institute events and member activities and opinion. We welcome your feedback, and encourage readers to forward issues to friends and interested parties.

I would also urge readers to subscribe to the paper issue of The Immortalist (see http://www.cryonics.org/info.html ) as not everything is reproduced in this email version.

NEWS & VIEWS
American Cryonics Society News & Views
EDITORS CORNER
BIOTIME FEATURED IN WIRED
Some "Senior" Personal Ads seen in Florida newspapers
Cryostats Status Report, June 2004
QUICKIES
LIFE EXTENSION NEWS
The Highest Law


NEWS & VIEWS

President's Report

This issue of THE IMMORTALIST (as with the previous issue) is being sent gratis to every CI Member (one per household) in the United States. This policy will continue at least until the end of 2004. Postage costs outside the United States makes the expense of regularly sending free issues prohibitive, but the last issue of 2004 will be sent to all CI Members everywhere (one per household).

This policy is being implemented on an experimental basis -- in 2005 we may either resume with fully paid subscriptions or switch to online publication. CI Members who have been subscribing will have their subscriptions extended in 2005 if paper-publication with paid subscriptions resumes, or can receive a refund if paper publication does not continue.

Since writing my last President's Report CI has had three more patients bringing the total for the first half of 2004 to five, about as many as we have ever had in any full year. I wish the quality of patient care had been better.

CI’s 63rd patient suffered a heart attack at home on Monday. He was not discovered and pronounced dead until several hours later. He was refrigerated at the morgue and soon released to one of our funeral directors who held him at water-ice temperature for over a day while it was determined whether financing was available to cryopreserve. Then he was cooled in dry ice for at least another day.

The Patient is a big man: 6' 3" and weighing nearly 300 pounds, he was too large for an insulated Ziegler (steel shipping coffin). Laying on an air tray he used a prodigious amount of dry ice. He is currently being cooled to liquid nitrogen temperature.

It is not feasible to perfuse after several hours of warm ischemia because of clotting and vascular damage. But neurological damage is slower and takes much longer. Dry ice cooling should have been initiated immediately upon discovery.

In the hope of reducing the number of losses of members living alone I have been testing two alarm systems with Robert Ettinger and plan soon to test a third. I will be reporting on my investigations in a forthcoming issue of THE IMMORTALIST.

CI's 64th Patient deanimated shortly after midnight on Sunday morning, May 16th. The event caught too many people by surprise. Knowing he had cancer, the member's paperwork and funding were in order. But he was living at home and apparently getting better thanks to his new Erbitux treatments.

His deterioration was very sudden -- he was in the hospital only about a day before his deanimation. The hospital staff was not informed of his cryonics arrangements, nor was many in his family, although his wife had signed a next-of-kin form. The funeral director had been forewarned and responded fairly rapidly. CI only learned of the deanimation from the funeral director.

The Patient's family should have understood the importance of contacting CI immediately when the member went to the hospital, the hospital staff should have been informed and persons willing to stand by to render immediate CPS should have been found. My commitment as CI President is that CI Members/Patients will benefit as a result of my being President. I am not proud of my role in this case. Complacency about apparently recovered cancer patients can be hazardous.

I have resolved to have more personal discussions with CI Members who are cancer patients, their family and their funeral directors.

Patient 65 was a "last-minute" case which demonstrated many of the things that can go wrong for people who sign-up at the last minute. We were initially contacted about 8pm Eastern Standard Time and the patient deanimated at about 4am EST the next morning.

The patient was a cancer victim living in the Los Angeles area. Both her son and brother were intent on having her cryopreserved, but did not have much familiarity with cryonics. They chose a funeral home and hospital well before the time they contacted us. They were unaware that we use cryoprotectants, but agreed to a credit card charge for us to express courier our perfusate to their funeral home.

We will not accept a full cryopreservation fee on a credit card and it takes the better part of a day to wire funds or express-courier a cashier's check. Too late we learned that the funeral home refused to do the perfusion, refused to allow anyone else to do a perfusion on their premises and objected to having two boxes of perfusate couriered to their address.

Our funeral directors' network cannot be utilized unless there is a commitment that a paid-up Member is at immediate risk. Without cash-in-hand we cannot be certain that a last-minute case will not result in a last-minute change-of-mind, so we had to find another funeral director outside of our usual network.

I contacted my friend Russell Cheney, who was in Florida. Russell has been a local response coordinator for Alcor in the Los Angeles area. In addition to his recommendation of a funeral director Russell gave me a list of phone numbers for Alcor volunteers in the LA area. I was reluctant to contact these people, thinking that there might be "political" ramifications to circumventing official Alcor approval. Later I decided I would try to contact them the next day -- which proved to be too late. I think a number of them would have agreed to stand-by and apply ice and CPR upon pronouncement of death. I would not have been circumventing official approval, either, because an agreement for such co-operation had been made at the CryoSummit, although renewing the discussion with the new Alcor administration would be a good idea.

Arrangements were made with the second funeral director and the courier was instructed to redirect the perfusate to his premises. The first funeral home was still responsible for the patient, however, and they phoned us at 4:30am informing us that they were removing the patient from the hospital. Incredibly, the hospital told the funeral home that they had no ice. We instructed them to get ice at a convenience store. The patient was transported back to the funeral home and placed in refrigeration.

After having initially agreed to take the patient, the second funeral director changed his mind and decided he didn't want to do it. Because we still did not have cash-in-hand we decided to work with a funeral director in San Diego who had done a previous case for us. We called the courier company and told them to redirect the perfusate to San Diego.

The first funeral home drove the patient to San Diego. When the San Diego funeral home opened two boxes from the courier company to begin the perfusion they discovered computer parts. The parts had not been expected, although they did belong to the funeral home (were correctly addressed) and were delivered by the same courier company. The courier company found the boxes of perfusate in a Los Angeles warehouse and sent them to San Diego. In their defense they said that good service cannot be expected when re-directing shipment twice en route.

As the general public learns more about cryonics I hope they also get the message that cryonics arrangements are not to be made while on a deathbed. Unfortunately, there are also many people who know a great deal about cryonics who think that last-minute arrangements are preferable for economic or other reasons. I think such people are making a big mistake.

A huge difference could have been made to patient care if one of our Members could have been on hand to render assistance. It would have helped even to get ice at a convenience store. Someone willing to stand by could have immediately packed ice on the patient and encourage hospital staff or a funeral director to inject heparin. If the Member-volunteer did not want to do chest-compressions, a hospital staff person might have been encouraged to do it.

I have created a column in our database that will indicate CI Members who may help in a cryonics case. We will not phone Members who do not give permission to be contacted and we will recognize that circumstances in your life may often mean you are unavailable. Cryonics is not an established industry and Members cannot afford to have a passive consumer-mentality. We are building our own lifeboats. We are few and far between. If we want others to help us when we need cryonics we should think of offering help to others.

If you may be willing to sometimes help in a cryonics case, please let Andy Zawacki (our CI Facilities Manager) know that you can be called. Send him an e-mail at CIHQ@... -- CIHQ (at) aol.com -- or phone

(586) 791-5961 or write 24355 Sorrentino Court; Clinton Township, MI 48035 with instructions to list you as a possible volunteer.

Elsewhere in this issue should be my review of available personal emergency response equipment, which could help reduce the time between deanimation and cryonics rescue -- or perhaps save lives. Those with a cell phone who can call an emergency number with the push of a button might get-along without these devices (although the situation may change when vital signs monitoring becomes available in 2005) -- as long as the phone call results in a reliable human connection.

Otherwise I recommend the Magnavox MobilePal+GPS which provides instant access to a live operator who can locate you for a monthly fee of $19.95. A drawback is the bulkiness of the device, which should be worn on the belt. For those who are house-bound a pendant or wrist-watch type "panic button" may be more convenient, but a product with a lower monthly fee than the Pioneer unit we have been testing might be as good.

I had been hoping to report on deployment of Dr. Yuri Pichugin's vitrification formula, but we received a setback. We were very encouraged by the fact that potassium/sodium ratios (a measure of viability) were as good for rat brains perfused with vitrification solution and cooled to -130oC and rewarmed, as for brains perfused without cooling. Even better, the less expensive commercial grade reagents are as good as the expensive grades.

The setback came when we tried to make electron micrographs (EMs). The results were terrible -- as bad for the samples cooled to -130oC as for the samples held at freezer temperatures. Based on the viability measures and gross appearance of rat brains and sheep brains perfused with vitrification formula, we believe the bad EM results were artifacts. In preparing EMs the brain is perfused with Karnovsky's solution in addition to the vitrification solution. They were stored for a long time at freezer temperature while we sought a good university lab to do the EMs. They were shipped at ice temperature, because we had no good way to ship at freezer temperature. We are uncertain of the quality of work at the university we chose.

Dr. Pichugin has now had to devote himself to studying how to better prepare EMs. He prepared another batch of samples, and this time he cut millimeter cubes from the brains and fixed them in osmium tetroxide.

We have sent these cubes to a Canadian lab which did good work for us before and are awaiting the results. EMs are frightfully expensive and it is a harrowing experience to be learning from EMs on a trial-and-error basis. Contributions to the Research Fund are always welcome and are tax-deductable. E-mail CIHQ@... or phone (586) 791-5961 if you have questions. Credit card payment is accepted.

Dr. Pichugin will be taking the month of July for a vacation in his native Ukraine.

He is preparing samples for EM work in Ukraine, which would be less expensive

-- although they must be carried at room temperature. He also hopes to find an inexpensive Russian light-microscope which he can buy for use in our Research Facility.

I myself will be spending much of July "on vacation" in China. I expect to attend the annual Society for Cryobiology Conference which is being held in Beijing this year (http://128.163.148.84/cryo2004/). With Robert Ettinger as Vice-President and Andy Zawacki as Facilities Manager, CI will be in good hands while I am away.

I remind all CI Members of the Cryonics Institute and Immortalist Society Annual General Meetings which are being held on Sunday, September 19, 2004 at the CI Facility in Clinton Township, Michigan. This will be an excellent opportunity to visit the Facility, meet other CI Members (along with Staff, Officers and Directors) and get a lively experience of the issues that face our organization. A buffet dinner is served to all who attend. Please notify us in if you do plan to attend. The AGMs are open to the public, but we must have advance notice of who is attending to plan for seating and buffet.

As announced on March 23 the Annual General Meeting (AGM) of the Cryonics Institute will be Sunday, 19-Sept-2004. There are currently 12 Directors and 4 of the 12 are elected to their positions every 3 years. The 4 Directors up for re-election this year are:

John Besancon

Royse Brown

Jim Fitzgerald

Edgar Swank

Any CI Member who is an Option One Member or has been a paid-up Option

Two Member for at least two years is eligible to be a Director and to vote for

Directors. A Director candidate must be nominated by another CI Member who

is qualified to vote, either at the AGM or beforehand (nomination in this forum

would be acceptable). A candidate need not attend the AGM to be elected.

An important qualification for a Director candidate is active use of e-mail insofar as most decisions are based on discussions held by e-mail. There is no requirement for physical presence at any meeting, so geography is not a limitation. (Two of our Directors currently live in the UK.)

It is not too early to be giving thought to who might make a suitable Director

or who might want to run for the office.

It seems likely that all the existing Directors will be candidates.

The AGM will be held at the CI facility in Michigan.

MEMBERSHIP COUNT JUNE 2004

Male 337

Female 118

USA 334

Non USA 111

Option One 339

Option Two 116

The eleven "lost" Members I reported earlier have mostly been found, but we have changed the definitions slightly. By our current definition a "lost" Member is someone for whom we do not have a current address, but for whom we have a good prospect of getting a current address. We have two "lost" Members based on the fact that we are getting a message on their answering machine and we are expecting to eventually make contact.

Not counted as Members are those in our "inactive" file. This includes people who have renounced their membership and who say they want to be cremated or buried rather than cryopreserved. Such people may change their mind again, in which case they can be activated again upon request if they are Option One. Option Two Members who have stopped paying dues must pay an initiation fee and resume dues to be activated again.

Member we have inactivated is a man we believe is now living in South Africa who has not contacted us since five years ago when he was living in Michigan as a University student doing a PhD thesis. His e-mail address and mailing address are defunct. If he contacts us and gives us an address, we will reactivate him.

Ben Best

___________________________

WILLIAM’S CONTROVERSY CONTINUES

The controversy surrounding the suspension of Ted Williams by Alcor continues

The latest development is that an Arizona paper has entered the fray. The Arizona Republic has joined the daughter of Ted Williams in a court battle to view documents held by a cryonics lab where Williams has been frozen to determine if he legally consented to have his remains stored at the facility.

The newspaper filed a motion late last week in Arizona Superior Court to unseal documents filed by Alcor Life Extension Foundation in response to a civil suit filed by Williams' daughter, Bobby Jo Ferrell, seeking to force Alcor to produce documentation proving that her father's remains were legally given to the Scottsdale cryonics lab.

`They claim to be in compliance with the Uniform Anatomical Gift Act but they want to hide everything they've done and they want to hide everything in the court file,'' Ferrell's attorney, John Heer, said of Alcor yesterday.

Ferrell has long wanted to claim her father's remains and have him cremated

based on his original will, but the body went to Alcor after his death in 2002.

Ferrell's half-brother, John Henry Williams, who died of leukemia in March,

reportedly obtained his father's approval to be placed at Alcor after his death.

John Henry's will states that his remains be kept at Alcor.

Although Ferrell gave up her right to claim her father's remains as part of a $215,000 settlement with his Florida estate, Heer is seeking to examine her father's contract with Alcor to see if it conforms with the Anatomical Gift Act.

If Ferrell’s attorney can prove Ted Williams was sent to Alcor without his written permission, he hopes to circumvent Ferrell's agreement with her father's estate and lay claim to the baseball Hall of Famer's remains.

Attorneys for Alcor have filed their responses and an affidavit opposing

Ferrell's motion under seal. The Republic, citing public access laws, has joined Heer's effort to have the Alcor court filings unsealed. ``Alcor has taken steps that are absolutely unheard of to seal the entire court file,'' said Heer. ``This is not your normal court situation so it's going to be interesting to see what happens." Just before we went to press, the Ferrell’s announced they were stopping all legal action. Stay tuned!

ANTI-AGING GROUP PLANS 2 EVENTS THIS YEAR

The American Association of Anti-Aging Medicine is planning two conventions this year. The first will be in Chicago on August 20-22. The second will be in Las Vegas on December 3-5.

Some of the subjects covered will be Stem cell therapy, Cosmetic office procedures, Brain aging, Laboratory biomarkers of aging, Nanotechnology, Obesity drugs and minimally invasive obesity surgery, Anti-Aging therapies, Heavy metals/environmental detoxification and Hyperbaric oxygen treatment.

The events are billed as "attracting 5000 physicians, scientists, exhibitors and key members of the industry and media."

For information call 1-800 558-1267

_________________________________

BOY COMES BACK FROM THE DEAD

An hour after a 22 month old boy was pronounced dead, a hospital nurse who was preparing the body for funeral home pickup noticed movement in his chest. He was submerged in a canal for 30 minutes after wandering away from his babysitter. An officer gave him CPR, and emergency workers tried to revive him, with no success.

He was subsequently removed to a local hospital in Boise, Idaho. A few days later his condition was still listed as critical.

________________________________

American Cryonics Society News & Views

By Jim Yount

Lots of people pitched in and donated time and talent to bring off the recent move of ACS patients from the CryoSpan facility in Southern California to CI’s Michigan facility. Thanks to all, and for the many suggestions on how to make the move safely. Our patients deserve no less.

When Paul Wakfer and others first formed CryoSpan, and the long-term cold-care facility was started, it offered a high level of patient care and a keen dedication to purpose. Everyone involved was cryonicists and expected to be their own customers.

ACS was immediately interested in contracting for liquid nitrogen storage of our own patients. The service was as promised: there were no "melt-downs," and the safety equipment such as the alarm system and the underground silos that housed the cryostats were innovative and practical. There was never a time when we were concerned that our patients were not being properly cared for.

CryoSpan did not get the boom in business that it had hoped for, and after the principal shareholders changed, it was decided that the facility, which shared space in a building dedicated to other kinds of research, would be closed down.

We are well satisfied with the care that ACS patients received at CryoSpan, and we are also pleased with the care that ACS patients have gotten at the CI facility. I have very mixed feeling about the move of our patients. On the one hand there is something to be said for the advantages of centralizing operations and what we hope will be an economic advantage in greater numbers of cryonauts cared for under one roof. On the other hand, the elimination of one of a very few competitors in the long-term storage business may mean that there is less innovation and perhaps even higher prices.

Our contact with the Cryonics Institute provides ACS patients with the same safeguards and oversight by our organization as did our contract with CryoSpan. The number of patients now under care by the Cryonics Institute, includes quite a number of other ACS patients, and is large enough that it seems unlikely we will have to do another patient move anytime in the near future. As to the far future, who knows? When my time comes to spend a hundred years or so in liquid nitrogen, it will not surprise me greatly to "wake up" on the far side of the moon! Now that will be a move!

Cryonics for All, or just for us Beautiful People?

An argument that has been around at least as long as I have been enrolled concerns who should be frozen. Oh, I don’t mean that there has ever been a serious effort to exclude anyone. We all agree that we need a few more good frozen men (and women). Rather, the disagreement is about who we should try to get to join our motley frozen crew.

Should we market to the masses? Is there really much hope that Mr. and Mrs. Mainstreet will become cryonics prospects? Or should we, instead, concentrate on the demographics that have yielded the very few "takers" that we have so far managed to stuff into cryostats?

There is no doubt that it is safest to take note of the characteristics of the takers and to then try to structure a marketing program to appeal to like folks. Good samples of cryonics patients are those who we recently moved from Southern California to Michigan. These included a schoolteacher, a lawyer, two NASA space program computer programmers, a welder, a housewife, two students, a technical writer, and a horse breeder. This group sounds fairly Main Street. It would be difficult to find a publication in which to advertise cryonics services that is read by a majority of these folks, unless it be a very general publication, such as a newspaper.

In order to appeal to the masses do we need to "dumb down" cryonics? Or perhaps we just have not been smart enough to present cryonics in a way that will be readily understood by ordinary folks?

I will confess that I don’t know who is right: those who think we can tap the Mainstreet market, or those who think we need to concentrate on attracting more Beautiful People? I like the idea of cryonics having a broader appeal, and I fervently hope that we can find better ways of explaining it so it is of interest to more people. There is also the danger that if cryonics becomes, or is regarded by most people, as too elitist, that very fact will make us a target for derision. If we can’t appeal to ordinary folks, let us at least avoid ticking them off!

What to do with the Dogs and Cats?

On my desk is a draft copy of a contact between the American Cryonics Society and the Cryonics Institute whereby CI agrees to keep frozen dogs and cats owned by members of ACS. This contract will be for the pets transferred in the recent move from Southern California, but the questions that must be addressed are pretty much the same for other pets of our members. The facts that people usually outlive their pets, and also have a great deal of love for them, suggests that there will be plenty more frozen animal companions in the future.

There are several contractual problems unique to pets that need not trouble us as much when dealing with people. Pets don’t make arrangements for themselves. They are dependent upon humans, and may or may not be happy being reanimated without their companion human. Who is to care for the reanimated pet? Should we require that pets not be reanimated unless and until their owner/companion human is also reanimated? What constitutes reanimation for pets? Should it be the same standard as that of humans? Should we first reanimate the pet’s owner, and then have him or her decide about the pets?

It may actually be a false assumption that pets require an owner or other sponsor to make decisions on the pets’ behalf, but humans do not. Certainly young children who are suspended don’t have the same capacity for reason as do adults, and may need such sponsorship. But what of the most intelligent cryonicists frozen today?

What if that intelligence, in relative terms, is akin to that of dogs and cats? The beings of the future, be they computers, super humans, or hybrids will likely be able to make decisions regarding reanimation and future lifestyle much better than will we. Should we then recognize that fact and demand in our own contracts that such beings be "owners" or "companion beings" to animals such as us?

We didn’t make the decision to freeze pets easily or lightly, and there are still quite a number of cryonicists who think we should not provide cryonics services to animals. It is interesting to note that all of the cryonics organizations now do accept pets, which probably is indicative of the inevitability of accepting such subjects.


EDITORS CORNER

We were recently on Florida’s west coast. While over there, we stopped in to see Curtis Henderson, who lives in Spring Hill with his son. Curtis, along with Saul Kent started the Cryonics Society of New York back in the 60’s. Considering that he had a stroke a couple of years ago, he’s doing pretty well for a seventy six year old.

Although his principal transportation is still his motorcycle, the last we heard, he and his brother were touring the country in his brother’s single engine plane. They recently stopped in Detroit to visit Robert Ettinger.

This issue carries another ad from the Life Extension Foundation. We thank them for the confidence they’ve shown in us, so as they say in the trade, "Please patronize our advertisers." Well, in this case, it’s a little more difficult.. The ad on page 14 pushes a web site that, based on information you type in tells you how many seconds you have to live and, your death date. I typed in the info as accurately as I could, and it told me I have 0 seconds to live, in fact I died in September of last year! I haven’t felt well since then. I saw no mention of LEF or their products.

I found out later that those with some time left on this earth are provided links to LEF products that could extend their life time. But, since I was already dead, there’s no sense in giving me the link!

Speaking of LEF, it’s not very often, (OK, it never happens,) that we see a familiar name when reading the "Letters" column of a magazine. Well, lo and behold, in TIME’s June 23rd issue, there was a letter from Bill Faloon, "Director, Life Extension Foundation."

It seems TIME ran a piece about the health benefits of red wine and the antioxidant compound resveratrol stating that Longevinex, a company marketing wine supplements is the only firm whose pills are made from real red wine extract from France. Well Bill corrected TIME, and got a little publicity as well. He didn’t say if the pills still provide a buzz.

A "LETTER TO THE EDITOR" in WIRED also caught our eye. It was in response to the treatment cryonics received in the piece on BioTime, page 15. The letter writer said….But why be embarrassed by the connection to cryonics? If cryonics can work, isn’t it much more "creepy" to let your loved ones rot or burn?

Peter Merel

Limpinwood, Australia

There’s a Peter Merel in Australia who’s a frequent cryonet contributor.

James Swayze’s advice about being a pleasant hospital patient is excellent, but it’s even more so for cryonics patients.

See CIYG Digest, page 11.

This past June 5th marked the 50th anniversary of the publishing of Robert Ettinger’s The Prospect of Immortality

It’s understandable, if anyone reading BACK IN THE SUN, page 14 is confused. For years we’ve been told to avoid the sun, and if you must be exposed to it, to be sure and use sunscreen. According to this, a lot of older people aren’t getting enough sun. But what really caught our eye, was the closing quote: "there’s not a whole of lot of direct evidence that sunscreens prevent skin cancer, and virtually none, that they prevent melanoma, the deadliest form."

What’s a person to do?


BIOTIME FEATURED IN WIRED

http://www.BiotimeInc.com

By John Bull

How low temperature surgery could kick-start the cryo game.

Preceded by an eye-catching graphic of a male nude resting in a giant ice cube, the article, written by Wil McCarthy reports on BioTime’s two main products, Hextend and HetaFreeze, and then gets into some cryonics bashing. It closes with an upbeat assessment on the future of cryo surgery.

Major surgery can be hell on a patient and procedures that require interrupting blood flow can be the worst because they starve the body of oxygen. One way to avoid these issues is to minimize the body’s oxygen demand, and the simplest way to do this is to cool the affected tissues. This has spurred a billion dollar industry in therapeutic hypothermia, in which a dozen firms hustle for market position. These companies have developed any number of devices, but they all have one shortcoming—they just cool a specific area. One drops a patient’s core temperature as low as 90 degrees. Any lower and blood thickens to sludge.

"It’s here that BioTime stands out from the pack. The company has developed a process that cools living bodies much further than that. Fifty-six degrees further, in fact, right down to the brink of freezing—a state in which the brain takes hours, not minutes, to wither.

BioTime’s secret is astoundingly obvious: antifreeze. The company’s flagship product, Hextend is an FDA approved blood volume expander designed to maintain blood pressure and chemistry in the wake of massive blood loss. BioTime has been testing Hextend in baboons, pigs and dogs, replacing their entire blood supply and then cooling them to 35 degrees. At that point vital signs cease. Bleeding virtually stops. Oxygen hungry tissues go on a diet. Then technicians raise the body temperature, reintroduce the blood, and shock the heart back to life. Right now, we can easily bring animals back from two hours of absolute clinical death," says Hal Sternberg, BioTime’s VP of research. "No pulse, no respiration, no measurable brain activity."

The company’s other main product, Hetafreeze, described as a cryoprotectant is still undergoing testing. So far they’ve been able to freeze tissue-- skin and hair, without cell destruction. It may allow whole organs, such as hearts, and even intact (but brain dead) organ donors to survive partial freezing.

"Clinical death for up to 15 minutes has been reversible since the 1952 invention of the defibrillator, now BioTime is on the brink of extending that limit to hours. But with the envelope pushing out further and further, the momentum is carrying the company into stranger territory. Especially given that Sternberg and his colleagues are longtime members of the cryonics movement, whose techno-utopian frozen head agenda is well known."

After describing the company’s experiments with vitrification, the article gets back to cryonics bashing. "Nonetheless, the medical establishment has shunned advocates of freezing bodies for eventual revival. And who can blame them. Cryonics is just plain creepy." It rehashes the whole Ted Williams/Larry Johnson/Sports Illustrated fiasco.

McCarthy softens his tone a little towards the end, "as far as anyone knows, there’s nothing physically impossible about reviving a frozen head. Still, when you get down to it, Alcor and Trans Time are taking money for a service that may never exist, and that even the companies estimate is 150 years down the road. BioTime is approaching the problem from the other end-the respectable end-by working to extend established medical procedures. The immediate benefit will be preventing untimely death in the here and now, which is completely different proposition than reviving the already dead."

For the fiscal quarter ending March 31, 2004 Biotime announced a 20% increase in royalty revenue from Hextend sales by Abbott Laboratories. "Hextend sales to the U.S. Armed Forces during the first three months of this year contributed to a significant portion of the increase in royalties we received," said JudithSegall, BioTime Vice President of Operations, Office of the President. Hextend is the preferred resuscitation fluid of the U.S. Special Operations Command.

__________________________________

Some "Senior" Personal Ads seen in Florida newspapers: (Who says seniors don't have a sense of humor?)

FOXY LADY: Sexy, fashion-conscious blue-haired beauty, 80's, slim, 5'4"

(used to be 5'6"), searching for sharp-looking, sharp-dressing companion.

Matching white shoes and belt a plus.

LONG-TERM COMMITMENT: Recent widow who has just buried fourth husband, and am looking for someone to round out a six-unit plot. Dizziness, fainting, shortness of breath not a problem.

SERENITY NOW: I am into solitude, long walks, sunrises. If you are the silent type, let's get together, take our hearing aids out and enjoy quiet times.

WINNING SMILE: Active grandmother with original teeth seeking a dedicated flosser to share rare steaks, corn on the cob and caramel candy.

BEATLES OR STONES? I still like to rock, still like to cruise in my Camaro on Saturday nights and still like to play the guitar. If you were a groovy chick, or are now a groovy hen, let's get together and listen to my eight-track tapes.

Paul Pagnato


Cryostats Status Report, June 2004

By Ben Best

Currently the Cryonics Institute has nine cryostats in service for storage of cryonics patients in liquid nitrogen. One cryostat is a capsule, three are rectangular and five are cylinders.

We call our custom-made fiberglass HSSVs (Hard-Shell, Soft-Vacuum)

units cryostats to distinguish them from the HSHVs (Hard-Shell, Hard-Vacuum) steel dewars manufactured by companies such as Minnesota Valley Engineering (MVE, acquired by Chart Denver in

1999. http://www.cryenco.com

Dewars have a very high vacuum ("hard vacuum") in an empty two-inch space between steel walls. Our cryostats have inner and outer walls made of fiberglass-resin composite that is very much stronger than either fiberglass or resin would be alone. The distance between the inner and outer walls is about a foot for the entire circumference of a cylindrical cryostat (or perimeter of a rectangular cryostat). Within that foot of space is perlite insulation packed loosely enough that a soft vacuum could be applied.

Vacuum is measured in units of air pressure -- similar to mm Hg (millimeters of mercury) used for blood pressure, but orders of magnitude lower -- zero microns Hg for a perfect vacuum. Some people use the term hard vacuum to refer to a pressure of one-third or less

of atmospheric pressure (atmospheric pressure is 760 mm Hg), whereas soft vacuum is any pressure less than atmospheric, but greater than hard-vacuum. Others (including cryonicists) restrict the term "hard vacuum" to pressures of a few microns or less, and "soft vacuum" to pressures greater than hard vacuum, but up-to but not greater-than a few orders of magnitude higher.

A strong vacuum pump creates the hard vacuum for a dewar at the time of manufacture -- a vacuum intended to last for 10 years. The vacuum is reinforced by getters, chemically reactive metals (usually barium, zirconium or their alloys), which react with oxygen, nitrogen, carbon dioxide and water vapor to further, harden the vacuum and keep it hard. The vacuums in our soft-vacuum cryostats are periodically reinforced by our Welsh-Sargent DuoSeal Pumps.

http://www.welchvacuum.com

The perlite insulation of the cryostats provides a backup for the soft vacuum. An armor-piercing bullet from a high-powered rifle could travel through the entire diameter of a cryostat or dewar. But a pistol bullet or forklift puncture would likely only put a hole in the outer wall of a cryostat. For a dewar, such a puncture would be an emergency demanding immediate removal of the patients. Even a dent can create a "hotspot" in a dewar. But the loss of vacuum in a cryostat might not be much of a problem because of the perlite insulation. There would be plenty of time to patch the fiberglass and restore the vacuum.

Although we have some patients who are quite tall and/or obese, we have not yet experienced any problem fitting six patients into one of our cylinders. There would be even less problem in the rectangular units where the patients lay flat and are simply stacked on top of each other 3 or 4 layers deep. In the cylinders the most crowding occurs in the area of the chest, with general narrowing toward the feet (partly due to the variation of abdomen and hip girth for men and women). There is plenty of legroom.

The cylinders and capsule are filled once weekly, whereas the rectangular units are filled twice weekly. The depth of liquid nitrogen ranges from 7.5 feet at the lowest to about 8 feet just after a refill. The level of liquid nitrogen in the most efficient cylinders drops only a bit more than 2 inches in a week (We will soon start filling these cylinders only once every two weeks.) So in the cylinders our tallest patients, at about six-and-a-half feet have at least a foot of liquid nitrogen above their toes at all times. Should a disaster occur -- which has not happened since we began service in 1976 -- the feet would be the first to suffer exposure and the head the last. The first cryostat built is designated HSSV-2, signifying that it is a Hard-Shell Soft-Vacuum unit holding two whole body patients. Hard-Shell means that the shell is hard enough to maintain shape when a vacuum is applied (ie, the walls do not collapse due to external or internal pressure).

A vacuum pump needs to be run on the cryostat or else it will lose the vacuum required to slow liquid nitrogen boil-off, but the pump is not so strong as to produce a Hard Vacuum in the sub-micron range, as is done with Alcor's dewars. (Cryostats are like big vacuum thermos bottles.)

HSSV-2, HSSV-R7, AND HSSV-R10, are the older model cryostats.

HSSV-2 looks like a big gelatin capsule propped-up at a 20-degree angle (or looks like a spaceship ready for launch). HSSV-2 is tilted so that the patients' heads can be down, but it couldn't be built to be vertical because the ceiling of the old building wasn't high enough. CI has three rectangular cryostats, designated HSSV-R7, HSSV-R10 and HSSV-R14, which hold 7, 10 and 14 whole-body patients respectively. HSSV-R7 is actually soft-shelled rather than hard-shelled because it only maintains its shape under vacuum due towooden supports between the walls.

Like HSSV-2, all of the rectangular units were built by CI facilities manager Andy Zawacki using epoxy fiberglass for the inner walls, polyester fiberglass for the outer walls and wood for structural support. The HSSV-R10 and HSSV-R14 were built in such a way as to avoid the use of wood between the walls -- because wood conducts heat. The HSSV-R14 unit ("the largest cryostat in the world") took Andy two years to build. He was too busy with the pressures and projects of running the CI facility and he was having problems with rashes from the epoxy fiberglass, which is needed to hold the liquid nitrogen. So it was decided that it would be necessary to contract with a manufacturer to build fiberglass cryostats.

Robert Ettinger favored an upright cylindrical design for units that would hold up to six patients. The first upright cylindrical unit, the HSSV-6-1, had structural defects. First Andy found a hole which he had to plug in order for the unit to hold a vacuum. When he put liquid nitrogen into the unit, it cracked -- forcing him to reline the inside with fiberglass.

The thick top conducts too much heat. Another manufacturer had to be found. The second manufacturer uses a type of fiberglass resin which is the same as one they use for liquid nitrogen testing of cruise missiles.

They gave CI good warranties on the quality of their work, which has been (for the most part) very good. Between the inner and outer walls of the cryostats -- in the area which takes the vacuum -- there is perlite, a non-corrosive, noncombustible, naturally-occurring volcanic glass used as an inexpensive insulator.

On HSSV-6-2 -- the first unit from the second manufacturer -- Andy did not notice that there was not enough perlite in the walls near the top until the unit was already being used for patients. The perlite had settled during shipment from the manufacturer. So HSSV-6-2 has poor insulation near the top. Andy took care to add an adequate amount of perlite before storing patients for the last three units received -- HSSV-6-3, HSSV-6-4 and HSSV-6-5, which are our most efficient cryostats. (HSSV-6-4 is currently only about as efficient as HSSV-6-1 and HSSV-6-2 because of the temporary lid, which will soon be replaced.)

Prior to getting the bulk liquid nitrogen tank we were paying 50 cents per liter for liquid nitrogen. But with the bulk tank, which holds 3000 gallons, we have only been paying 13.5 cents per liter. A

liquid nitrogen delivery truck that looks like a gasoline tank truck periodically fills the bulk tank, from which the cryostats are filled with liquid nitrogen through insulated pipes and hoses. On

the first of July the price of liquid nitrogen rises to 15.3 cents per liter. Using this price, I constructed the following table:

Cryostat Boil-off (liters/day) Cost per patient per year

CRYOSTAT DATA

HSSV-2 11.5 $319

HSSV-R7 58 $460

HSSV-R10 68 $380

HSSV-R14 61 $243

HSSV-6-1 19.5 $173

HSSV-6-2 17 $160

HSSV-6-3 10.5 $98

HSSV-6-4 17.5 $164

HSSV-6-5 10 $94

The most uncertain estimate is for the HSSV-2 which, because of its shape and positioning, makes it too difficult to calculate boil-off on the basis of drop in height. The estimate comes from information on page 4 of the June 1988 issue of THE IMMORTALIST. At that time a vacuum pump was running on the unit at all times and it was being filled from cylinders of known volume. Of all the units, HSSV-2 does the worst job of holding a vacuum.

Andy runs the vacuum pump on HSSV-2 constantly while he is in the building, but does not do so on his days off because of the risk of a machine failure that could result in complete loss of vacuum with no one present to notice. The worse the vacuum, the greater the boil-off.

HSSV-R10 & HSSV-R14 have a vacuum pump running about 16 hours per day, 4 days per week. Pressure after Andy returns from his days off work will be up to 40 microns Hg. HSSV-R7 does the best job of holding vacuum -- the pump only needs to be run about one or two days per month and pressure is rarely over 20 microns Hg. The HSSV-6 cylindrical cryostats are vacuum pumped about one day every two weeks, with vacuum as high as 40 microns Hg. Although the HSSV-R7 is the most efficient at holding a vacuum, the wood in the walls causes heat loss.

The HSSV-2 cryostat has the most sentimental value and is the most photogenic, but it is a pain to maintain (including checking liquid nitrogen levels, which is done daily for all the cryostats). HSSV-2 is the first cryostat I would replace. The future looks bright for the HSSV-6s, however, because of their wonderful efficiency.


QUICKIES

I should prefer to an ordinary death, being immersed with a few friends in a cask of Madeira, until that time, then to be recalled to life by the solar warmth of my dear country! But in all probability, we live in a century too little advanced, and too near the infancy of science, to see such an art brought in our time to its perfection. Benjamin Franklin in 1773 WIRED

NASA Funds Sci-Fi Technology The NASA Institute for Advanced Concepts (NIAC) funds long-range,wild ideas, such as a space elevator, shape-shifting space suits, antimatter-powered probes to Alpha Centauri, Robotic armada to destroy incoming asteroids, and a way to move a hurricane with satellite-beamed microwave energy....IBID

Hydrogen Cars The Department of Energy has found that nanotechnology could reduce the high costs of hydrogen cars by developing revolutionary ways of producing and storing hydrogen.

Hydrogen stores energy more effectively than batteries, burns twice as efficiently in a fuel cell as gasoline does in an engine, and produces a single waste product, water. Kurzweil Newsletter

Reef burials. We’ve reported previously on the ingenious ways we Americans treat our deceased. Here’s another! Eternal Reef’s Inc. takes cremated remains, mixes them with cement, and forms them into balls resembling igloos with holes to provide hiding places for fish. In late April, just off Ft. Lauderdale, reef balls containing the ashes of 16 people were lowered 65 feet to the ocean floor. The company, located in Atlanta, Georgia offers a number of models, the most expensive is a 4000 pounder that sells for $4995. (delivered?) FLORIDA TODAY

Does your doctor wear a tie? Researchers at New York Hospital Medical Center sampled ties from doctors, assistants and medical students. Half the ties contained disease carrying bacteria. By contrast, only 1 of 10 tie wearing security guards tested positive. Ibid.


 

LIFE EXTENSION NEWS

All About Antioxidants

The right diet can help fight aging. By the year 2020, an expected 70 million Americans-about one in five of us-will be 65 or older. While we may not be able to halt the passage of time, we do have some control over our biological age.

There is a clear connection between the foods we eat and the rate at which our bodies age. By living a healthy lifestyle and enjoying a diet rich in colorful foods, you can help keep your body feeling young and ward off some of the effects of time.

THE STRESS OF OXIDATIONWhile oxygen is essential for life, it's also one cause of aging. Unstable" oxygen molecules, called free radicals, initiate detrimental changes in the body that result in deterioration and aging.

To counteract the effects of free radicals, we need enzymes and vitamins. "When the number of free radicals exceeds our bodies' ability to subdue them, the power shift is called oxidative stress," says Cheryl Forberg, RD, author of Stop the Clock! Cooking. "This stress, or free radical burden, attacks healthy cells. Their accumulation ultimately results in a series of events that leads to oxidation and the process we call aging."

ANTIOXIDANTS TO THE RESCUE

We've all heard about the benefits of antioxidants, and one group of them packs a particularly powerful punch against aging. Pigments that give plants their bright colors are called phytonutrients.

Colorful fruits and vegetables "protect your genes and promote your health and longevity... Each [color] group contains important antioxidants that detoxify free radicals to protect your genes," says Marcia Zimmerman, CN.

Add the following foods to your diet, and graze throughout the day. "The afterlife of dietary antioxidants in our bloodstream is about six hours. Therefore, regular intake throughout the day optimizes antioxidant levels in the bloodstream," says Forberg. Who knew that an anti-aging regimen could be so delicious?

ASPARAGUS, BROCCOLI, & CABBAGE These green vegetables help repair genes, improve cellular nutrients, and detoxify the body. This family of veggies is packed with anti-aging nutrients, including lutein, quercetin, and beta carotene.

BERRIES The bluish-red pigments in blueberries, cherries, grapes, cranberries, and raspberries protect against both cancer and heart disease. An average strawberry contains about 200 seeds, each a concentrated source of ellagic acid. This antioxidant promotes healing and also fights cancer and heart disease.

GARLIC & ONIONS Garlic promotes heart health by lowering cholesterol, and compounds in onions may help with the liver's detoxification process.

GRAPES Purple grape seeds are loaded with antioxidants, and many juice companies are extracting these antioxidants and pouring them back into the juice. Recent studies show that regular consumption of grape juice may have significant cardiovascular benefits.

PLUMS Studies show that five dried plums a day can slow the oxidation process and decrease LDL cholesterol. The high levels of fiber promote regularity and maintain healthy glucose levels.

BROWN RICE & OTHER GRAINS Tan carbohydrates balance hormones. Whole grains have three groups of phytochemicals, which translates into antiaging antioxidant activity that exceeds most vegetables. Adapted from Greenwise

_________________________________

High Fat Breakfast May Raise Heart Risks

Within an hour of eating a large high-fat, high-carbohydrate breakfast; the body starts making inflammatory chemicals associated with clogged arteries, a new study has found. These inflammatory factors stay high for three to four hours, and that's when many people sit down to another meal.

"This kind of eating probably keeps the average American in an inflammatory state all day. Thank God he sleeps at night," said

. Dr. Paresh Dandona, the study's senior author. This nearly continuous state of inflammation, he said, helps explain why obese people are at higher risk of heart attacks and strokes.

Dandona, chief of endocrinology at the State University of New York at Buffalo, and several colleagues studied nine normal weight adults who fasted overnight before eating a McDonald's Egg McMuffin, a Sausage McMuffin and two servings of hashbrown potatoes. (That meal came in at 910 calories, with 81 grams of car:bohydrates, 51 grams of fat and 32 grams of protein.) Dandona said many people regularly consume even less healthful meals.

The nine breakfast eaters were compared with eight normal-weight adults, each of whom was given a 10-ounce glass of water after an overnight fast. Researchers tested participants' blood before they ate or drank anything and then one, two and three hours afterward. The calorie-laden breakfast increased levels of free radicals, C-reactive protein and nuclear factor-kappa B, a protein that triggers the release of inflammatory chemicals.

"This substantiates what scientists have been saying all along: Don't. overeat," said Cathy Kapica, director of global nutrition for McDonald's Corp. in Oak Brook, ill. Results of the latest study appear in the April issue of the American Journal of Clinical Nutrition. Adapted from FLORIDA TODAY

Speed up Your Fitness Results

Editors at Fitness magazine share three. surefire "truths" that will burn calories, boost metabolism and keep you motivated.

You need to use a challenging weight. Any form of resistance dumbbells, barbells, tubing, even your own body weight - helps you sculpt lean, sexy muscles. The catch: You need to use enough resistance to challenge the target area. Most experts agree you should feel some fatigue by the eighth rep. If you can breeze through 15 reps, it's time to add more . weight.

Intensity matters. Exercising in the low-intensity, so-called fat-burning zone feels comfortable. That's the problem: Going at an easy pace for 30 minutes offers some benefits, but you can get more out your workout in that same time by pushing yourself harder. Slow and steady has its place - especially for endurance training but for best results, incorporate intervals (bursts of higher intensity followed by recovery periods) into at least one weekly cardio workout. You'll teach your body to work harder and temporarily boost metabolism.

The fastest way to bum calories (and lose weight) is with aerobic exercise. A number of recent fitness books maintain cardio is a waste of time if you want to lose weight. But aerobic exercise is crucial not just for blasting fat but also for maintaining good health.

In a review of 262 studies, the American College of Sports Medicine concluded you need 20 to 60 minutes of cardio three to five times a week (plus two or three days of strength training) for optimal fitness and weight maintenance.

Hundreds of studies have shown cardio also is key in fighting heart disease, diabetes, cancer and other chronic ailments. Ibid

_________________________________

Look For beta carotene, Not retinol

EXCESSIVE AMOUNTS OF FAT-SOLUBLE RETINOL or preformed vitamin A-has been linked to weak bones, even though adequate amounts of this vitamin are needed for bone growth. A 30-year Swedish study found that men with the highest levels of retinol in their blood suffered seven times the number of bone fractures as those with lower retinol levels. And intakes of 4,500 to 5,000 IU of retinol were linked to increased incidence of fractures in a Harvard study.

Fortunately, research finds no such relationship between plant sources of beta carotene and other carotenoids, which the body converts to vitamin A as needed. So eat plenty of brightly colored fruits and vegetables: sweet potatoes, carrots, spinach, kale, cantaloupe, and apricots. And look for carotenes and carotenoids in addition to preformed vitamin A in your daily multivitamin.

_________________________________

Dietary Panel Calls For More Fish, Fewer Refined Grains

An Agriculture Department advisory group is urging the government to revise the food pyramid to emphasize more fish and fiber and fewer refined grains such as white bread. The group recommends that salmon consumption should be increased to two times a week

With two thirds of Americans overweight, the panel also is urging better portion control, noting that folks are inclined to overeat when there’s more food on their plate.

Another suggestion is that people should count calories as opposed to carbohydrates or fat. Burning more calories than the dieter takes in is more important than where the calories come from.

Turning their attention to exercise, the committee said adults should get 30 to 60 minutes of moderate to strenuous exercise daily. FLORIDA TODAY

Alternative Medicine’s Popularity Growing

A recent government study said more Americans are opting for non-traditional treatments for physical ailments. Yoga, meditation, herbs and the Atkins diet are growing in popularity perhaps because of dissatisfaction with conventional care.

Here’s the most common forms of alternative medicine in the United States, according to a 2002 survey of 31000 adults:

Prayer for own health 43%

Prayer for other’s health 24%

Natural products, herbs, botanicals 19%

Deep breathing exercises 12%

Prayer group participation 10%

Meditation 8%

Chiropractic care 8%

Yoga 5%

Massage 5%

Diet based therapies—Atkins, Ornish, Pritikin Zone diets 4%

FLORIDA TODAY

Can't eat beef…………………….mad cow

Can't eat chicken…………..… ….bird flu

Can't eat eggs………........ again, bird flu

Can't eat pork.....fears that bird flu will infect piggies

Can't eat fish.......contaminated by heavy metals in the water

Can't eat fruits and veggies....insecticides and herbicides

Damn!........... That just leaves chocolate!

Bits & Pieces

And a short piece in FLORIDA TODAY reports on some research done at the University of California in San Francisco. Seems they’ve found that flavonoids in dark chocolate relaxed blood vessels, increasing blood flow to the heart. "The study, which adds to a growing body of evidence for the heart benefits of dark chocolate, appeared in The Journal of the American College of Nutrition."


 

The Highest Law

Sara L. Olson

As someone who veraciously embraces life, even speaking the word "suicide" leaves a rancid taste in my mouth. The thought of willingly releasing my grasp upon this world is not something I would like to entertain. But if I ever came to the point at which I knew my death was inevitable, particularly as the result of a degenerative disorder, I would want to preserve my body at a point where I was as healthy as possible. I plan to utilize this body at a later date, after all, and I want to be as complete as possible when I do so. I prefer this option to forced deterioration and personality loss. From my perspective, the "end" of my suffering is secondary to the preservation of my self.

The recent death of former President Ronald Reagan prompted further contemplation for me regarding assisted suicide. Medical authorities diagnosed Reagan just over a decade ago with Alzheimer’s disease. By the year 2000, the press reported that his deterioration was escalating. He could no longer recognize anyone but his wife.

The former President’s family and associates were rather tight-lipped about the nature of his condition in the few years up to his death, but it can be assumed that if his condition was so advanced in 2000, by his death a few weeks ago, there was not much left of the man his friends and associates had once known.

Millions of people struggle with this and similar terminal degenerative disorders every year, either as patients afflicted with the disease or loved ones forced to endure prolonged suffering as they watch those they care for slowly dissolve into oblivion. This would be the ultimate loss for cryonics patients hoping to preserve themselves for the future. The mind, including the memories and thoughts that make each person unique is, after all, what the cryonics patient hopes to save, beyond the preservation of the body. Ultimately, degenerative diseases such as Alzheimer’s are the worst fate for a cryonics patient. But worse is the thought that the possible salvation of a cryonics patient’s future is kept from them.

Assisted suicide has been demonized in the United States by those who are dogmatically opposed to the idea of anyone but a higher deity taking control of life and death. The attempts by this small group to take control of the fate of others who may or may not believe as they do has resulted in the continued illegality of assisted suicide.

I resent the idea that someone can dictate whether I can choose to participate in an assisted suicide. My life is precious; I intend to live as long and as fully as possible. But, inclusive to that, I want to be able to legally choose to end my life for the purpose of saving it later, and I support the right of anyone else who chooses to end their own life as well, even if they have different reasons for wanting to do so.

I have been fortunate enough to see very few people I am close to die in my lifetime, and none of them died in such an agonizingly degenerative fashion as Reagan and others like him.

All of my experiences with Alzheimer’s have been once removed; a friend’s grandmother or grandfather who slowly decayed before death, losing their mental cogency and personality at a terrifying pace. I know that if I were in the position my friends have been in, with a loved one slowly withering away, and that person asked me to help them end their life while they were still happy and relatively comfortable, I'd want to do what I could to fulfill their wishes and would be infuriated that the law kept me from helping them.

One thing that would aid the cause of assisted suicide greatly would be changing the definition of death. For a cryonics patient who plans to return, "assisted suicide" really isn’t death at all, since death in all other cases results in the permanent cessation of function and decay of the body, and the choice of "assisted suicide" for a cryonics patient is actually instead a calculated choice to enrich a patient’s life at a later time.

Using assisted suicide in conjunction with cryonics is, in fact, an optimistic and life-affirming decision, particularly when the cryonics patient is standing upon the precipice of a terminal degenerative disorder. Cryonics is life, and people deserve the opportunity to embrace that life with every vital fiber of their being. Volitional suspension is not a choice that I would enjoy making, but it certainly beats death and decay.

I choose to embrace life.

 

 
CRYONICS GROUPS WORLDWIDE
 
UNITED KINGDOM: There is a large, enthusiastic and active group that meets every month under the name CRYONICS EUROPE. Visit them at: www.cryonics-europe.org. Activities include discussion, CI standby team training, videos,and social events. All visitors, and new and prospective members are welcome! Please contact: Mark Walker, C.E. Membership Manager at davros@.... Tel.UK:01543-674129, Mobile: 07970-254948.
 
NETHERLANDS:

 This is a very keen and growing group anxious to expand. Contact George Overmeire at Giorgio@... or telephone +31-(0)6-51-454237

IRELAND:

Peter Thornbury and his wife are attempting to organize a CI group in Ireland. Peterhas homes in both the north and south of Ireland, and welcomes any contacts. He may be contacted by mail at: Peter Thornbury, 50 Lough Road, Lurgen, County Armagh, North Ireland. Email messages for Peter Thornbury should be sent via the UK group. (See above.)BELGIUM:

 A new website in Dutch and French is being setup for Belgian cryonicists. Contact David Verbeke at: davidverbeke@..., or email cryonicsbelg@... for further information.CANADA:

 This is a very active group that recently participated in Canada’s first suspension. President, Christine Gaspar, Vice President, Gary Tripp, Secretary/Treasurer, Ben Best. There is a sub-group called the Toronto Local Group. Meeting dates and other conversations are held via the Yahoo groups address: cryonicssocietyofcanada@yahoogroups.com

DENMARK: A new Danish support group has emerged and is online -- the Danish Cryonics Support Group. Contact them at: http://www.cryo.secureid.com, or at: david.stodolsky@...

JAPAN: Hikaru Midorikawa, President of the Japan Cryonics Association is attempting to reach to anyone living in Japan, and interested in Cryonics. He can be reached at:Hikaru@...

AUSTRALIA:

Theo Tatton, CAA’s Executive Officer advises us that the CAA has a bulletin board: Caa-list@... Their Public Relations Officer is Phillip Rhodes. They have an annual meeting alternating between Sydney and Melbourne. Their mailing address and phone number are: P.O. Box 57, Hampton Vic. 3188 Australia Phone 61-3-9-9589-6236ITALY

Am looking for contacts in Italy or Ireland who are interested in forming a Cryonics Support Group. Anyone with a knowledge of Italian law would also be very welcome. I was born in the UK, have Dual Italian/UK Nationality & speak both fluently. Please contact me in Cassino, Pr.Frosinone, Italy on 0039-347488-9679 or my house in S.Ireland (mainly Summer)on 00353-(0)87246-4538, Aldo Fusciardi

SPAIN

Giulio Prisco is Secretary of the Spanish Cryonics Society. He lives in Madrid .and he’s a life member of CI. and is willing to serve as a contact point for Europeans. He can be contacted at: cell phone (34)610 536 144 or gpmap@...


 
Small Print:

For more information about cryonics or Cryonics Institute and how to become a member, visit our web site at http://www.cryonics.org.

We encourage readers to forward issues to friends and interested parties. Please send any suggestions or comments to Long Life by emailing John@...

Long Life would like to thank Longevity Report, Wired News, InfoBeat, The New York Times, The New Scientist, Nanodot, Slashdot, contributors to the Extropian and CryoNet mailing lists, members of the Cryonics Institute, and others, for helping provide some of the free public information used in Long Life.

(Disclaimer: CI does not necessarily encourage or advocate the use of any products or practices mentioned in its newsletter.)


--
Sincerely, John de Rivaz: 
http://John.deRivaz.com for websites including Cryonics Europe, Longevity Report, The Venturists, Porthtowan, Alec Harley Reeves - inventor, Arthur Bowker - potter, de Rivaz genealogy,  Nomad .. and more

#30 From: "John de Rivaz" <John@...>
Date: Wed May 12, 2004 9:48 am
Subject: Long Life vol 3 no 4 - Immortalist Highlights May-June 4004
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Long Life: the Cryonics Institute newsletter

May 2004 -- Volume 3, Number 4 - Immortalist Highlights

Welcome to Long Life -- the electronic newsletter of the Cryonics Institute. We're here to update you with brief cutting-edge news, updates, links, and information about the latest scientific, medical, health, anti-ageing, and social developments relevant to CI's goal of saving, preserving, and extending human life. Long Life may also include news about Cryonics Institute events and member activities and opinion. We welcome your feedback, and encourage readers to forward issues to friends and interested parties.

I would also urge readers to subscribe to the paper issue of The Immortalist (see http://www.cryonics.org/info.html ) as not everything is reproduced in this email version.

News and Views
Meet Brent Fox
Quickies
Perpetuities
Deanimation
Who's Big in 2024
Life Extension News
Cryonics Groups Worldwide


NEWS & VIEWS

PRESIDENT’S REPORT

The biggest news is the move of ten American Cryonics Society patients from CryoSpan in California to the CI facility in Michigan. The move is well documented and photoessayed elsewhere in this issue of THE IMMORTALIST. [NB You have to subscribe to get the photos]

CryoSpan has not been accepting new patients for nearly five years. Located in the Critical Care Research facility and maintained by a 21st Century Medicine researcher, CryoSpan was a burdensome responsibility interfering with research. Lengthy negotiations involving financing delayed the move for years, and a further delay resulted from the Cease & Desist Order against CI last Fall. CI's licensure as a cemetery and the Spring-thaw of icy mountain roads finally made the move a reality. Now CryoSpan can cease operation and the researchers can concentrate on research.

The Cryonics Institute patient population now stands at 62, only slightly more than the 60 patients at Alcor. Aside from the CryoSpan move, CI has had two new patients so far in 2004 and we are monitoring other critically ill Members who are likely to require our services soon.

As described elsewhere in this issue of THE IMMORTALIST, an elderly CI Member who died of coronary artery disease at the end of March was cremated by a cousin who had signed a Consent/Release form for cryonic suspension. Because the Member was cremated rather than cryopreserved, the cousin will inherit the money that would have gone for cryopreservation. Giving a trusted friend or cryonicist the Power of Attorney for Health Care may be a better idea in many cases that allowing a next-of-kin (who has the default power) to exercise control if that next-of-kin has a negative attitude toward cryonics or the wishes of cryonicists.

Progress is being made toward vitrification of CI patients. I have examined sheep brains perfused with Dr. Pichugin's new vitrification solution and glycerol, and to the naked eye the vitrification solution perfused brains look much less dehydrated and show no sign of ice crystals -- in contrast to the glycerol-perfused brains.

I have been learning about Electron Microscopy (EM) and I have phoned nearly 20 EM facilities (mostly university-affiliated) to find the best service at the a reasonable price. One University EM facility has particularly impressed me with their professionalism, pricing and friendliness.

We have sent them two rat brains for EM analysis. Both brains were perfused with the new vitrification solution, but only one of them was cooled to -130oC. Hopefully, we will be able to report the absence of freezing damage, but if not I expect damage will be greatly reduced.

We will continue to strive for perfection, but we will not deprived our Members of improved treatment while we are short of perfection.

We hope to deploy the new vitrification solution in our cryonics protocol within a month. Tax-deductable donations to the Research Fund are a welcome assistance to our efforts. [E-mail CIHQ@... if you have questions about donation -- or phone (586) 791-5961 with questions or your credit card number.]

Thanks to the generous donations of Hugh Hart, many persons have been receiving THE IMMORTALIST without having to renew their subscriptions. Hugh Hart is now one of our patients and the Immortalist Society can no longer affort to underwrite subscriptions. Renewal notices have been mailed to everyone who is not paid-up. Subscription renewal information can be found on our website http://www.cryonics.org/info.html or elsewhere in this issue of THE IMMMORTALIST (or pay by credit card by phoning 586-791-5961).

Although we are not aggressively looking quite yet, the time is approaching when we will need another full-time employee working at the Cryonics Institute facility in Clinton Township, Michigan. We would want someone who is reliable, competent, willing to work for a modest wage and someone who is likely to remain with us for many years (ie, someone wanting to devote the rest of his/her life to cryonics and who has the prospect of living for quite a few more years). The job would include both office work (Member paperwork, computer data-entry, etc.) and physical labor (cryostat maintenance, patient perfusion assistance, etc.) Anyone interested should contact me at benbest@....

Robert Ettinger is kindly testing two emergency monitoring systems. I will shortly be obtaining a third. I expect to be reporting on all these systems in the next issue of THE IMMORTALIST.

CRYONICS INSTITUTE MEMBERSHIP COUNT

Counting sheep is simple enough to put you to sleep, but trying to count people can give you nightmares. Nonetheless, I have attempted to compile a count of Cryonics Institute Members as of 8-April-2004. Keep in mind that the definition of Membership for CI is a person who has ever paid the Option One Fee or is currently paying Option Two Dues. It is therefore possible for a person to pay the Option One Fee without ever making any arrangements for cryopreservation -- no paperwork or funding.

Nonetheless, not many people are so foolish as to pay the Option One fee without some intention of making arrangments.

Literally speaking, the Cryonics Institute has 453 Members as of 8-April-2004. However, eleven of those members are "lost" -- we have no current address or contact information.

They could even be dead. I am hot on the trail of a few of the lost Members, but the trail is very cold on some others.

We did have a Member who refused to give us an address, but she has now given us a mailing address, so I am counting her as "found".

Of the 442 "in touch" members, I present the following statistical summaries.

BY GENDER

Male....328

Female..114

BY COUNTRY

United States....332

England.............43

Australia............17

Canada...............14

Netherlands.........8

Germany.............6

Spain...................4

Sweden...............3

Belgium.............2

New Zealand.......2

Austria...............1

Chile..................1

Denmark............1

Greece...............1

Italy...................1

Japan.................1

Malta.................1

Mexico..............1

Russia...............1

Switzerland.......1

Ukraine.............1

BY STATES IN THE USA (5 or more Members)

Florida.............36

Michigan..........33

California.........33

New York.........28

Texas................26

Colorado...........15

Kentucky..........13

Illinois..............11

Arizona............11

Maine................9

Pennsylvania.....8

Washington.......8

Georgia..............8

Indiana..............7

Massachusetts...7

New Jersey........6

Virginia.............6

Maryland...........5

North Carolina..5

Ben Best

_______________________________

CI MEMBER CREMATED BY COUSIN

Toward the end of March an elderly CI Member collapsed in the street and was taken to a hospital where he died of coronary artery disease. The man had been an Option One CI Member for nearly nine years. He had prepaid the $28,000 required for his cryopreservation, which we have been holding on his behalf. His closest relative is a first cousin who was designated as the Member's primary heir on the Member Questionnaire. The cousin signed a "Consent/Release for Cryonic Suspension" form shortly after the Member joined CI.

Early in April we received an e-mail from the cousin indicating that the Member had "regrettably" been autopsied and asking how the prepaid funds could be returned. A series of e-mails were exchanged over a period of a week or more after which we received an e-mail indicating that the Member had been cremated. These e-mails are the only information we have concerning the conditions surrounding the Member's death.

We don't know how long the Member was in the hospital before he died. We don't know what kind of autopsy was done -- if it concerned a heart investigation the brain may have remained intact, although a week or two at refrigeration temperature would have resulted in considerable deterioration.

Five days before the cremation Robert Ettinger demanded the body, but the cousin saw no reason to send "mutilated" remains. Partly because of the condition of the remains I was reluctant to threaten legal action, but I finally did so a day before the cremation. The cousin may not have been checking his e-mail, but when he did reply he said that we were too late because the cremation had been done.

At one stage of the e-mail exchange the cousin said that he was away on business at the time. (The time of the collapse? The time of the autopsy?) At another stage the cousin insisted that the Member had told nurses that he wanted his body donated to science. The cousin insisted that this could not be a reference to cryonics or else the Member would have said cryonics. The cousin indicated that he had attempted to honor the Member's desire to donate organs, but that medical authorities regarded the elderly body to be unsuitable. Presumably if the cousin believed the Member still wanted cryonics he could have honored that wish and requested cryonics protocol -- rapid cooling at least -- or a restricted autopsy.

Possibly the Member did tell nurses he wanted his body donated to science, but if so he probably meant cryonics. In 2002 the Member requested and received a large set of back issues of THE IMMORTALIST. Also in 2002 he had received a new CI bracelet. The fate of the bracelet is unknown.

The Member indicated in his "Rider A" that in the event that he was not cryopreserved that the money should be given to his estate rather than to CI. Thus, the money goes mainly to the cousin -- the primary heir. The CI Board of Directors recognizes that CI must return the money because CI has not delivered service and because of the stipulations in Rider A. To have held on to the money would have made CI appear as money-grubbing as the cousin appears to have been (even more money-grubbing to media, if media attention was attracted).

If there is an object lesson here for CI Members it is that it can be dangerous to entrust one's cryopreservation to a person who would greatly benefit from a failure to cryopreserve -- especially when that person has little respect for cryonics or the wishes of the cryonicist.

A CRYONICS POWER OF ATTORNEY

I do hope that the recent cremation of a CI Member by his cousin has raised some alarm bells among CI Members concerning the possible dangers represented by the legal powers of nearest relatives who are not cryonicists or respectful of the wishes of cryonicists.

Not a single member of my rather large family has any interest in cryonics. My brother thinks I am a "chicken shit" for not wanting to "die like a man".

Most of the rest are very fundamentalist. For this reason I have made Canadian cryonicist Christine Gaspar my Power of Attorney for Personal Care in a document drawn up by Bruce Waugh (who is a Canadian cryonicist and lawyer) and by Christine Gaspar (who is a Canadian cryonicist and emergency medicine nurse).

The key features of this document are that my Power of Attorney is directed to ensure that I want life support to continue if I am in a vegetative state, but that if it is determined that to continue in that state then a cryonics rescue team is to be assembled and life support withdrawn once the cryonics rescue team is in place. A copy of the document is on the Cryonics Society of Canada website:

http://198.173.255.200/cryocdn/attorney.html

As you can see by examining the document, it makes reference to Canadian statutes which would not be applicable to CI Members not living in Canada. Perhaps the UK CI Members could modify this document for their own needs and I will ask David Ettinger if we can make a similar document available on the CI website which would be suitable for CI Members living in the United States.

The bottom line is that if you have friends who are more supportive of cryonics than your relatives, you should strongly consider giving those friends the Power of Attorney over the fate of your body rather than allowing your relatives to have that control.

Ben Best

CRYONICS POWER OF ATTORNEY FOR PERSONAL CARE

In the United States, Living Will and Power of Attorney for Health Care are implemented on a state-by-state basis. The "Partnership for Caring" acts as a clearing-house by providing state-specific information about these matters. They have a hotline at 1-800-989-9455 which anyone with questions is free to call. You can try entering your state and other information to download these legal documents:

http://www.partnershipforcaring.org/Advance/documents_set.html

Remember that a cryonicist would not want life support withdrawn before a cryonics rescue team is in place. And a cryonicist must be clear that his/her physical remains are to be cryopreserved. The California Advanced Health Care Directive combines the ability to appoint an agent (Power of Attorney for Health Care) with the ability to give directions to that agent (Living Will) concerning Health Care and Final Wishes:

http://www.cmanet.org/publicdoc.cfm/7

________________________________________

FRENCH LASER PROJECT

Yvan Bozonetti announced on Cryonet that he expects to begin construction on a French laser experimental project. It’s aim is to build a technological center geared towards brain reader-scanner at molecular levels. More broadly, it would put in public hands some high technology such as powerful lasers or cryogenic technologies and some more basic ones such metal working or casting. Blueprints for the first unit may be seen at: www.freewebs.com/mz2/lesite.htm

He has the building permit and has closed the first round of financing.

AN 1800 MILE ODYSSEY

By John Bull

The move was originally planned for last fall, but had to be cancelled because of CI’s problems with the State of Michigan. Once these problems had been resolved, planning resumed. The planners were Jim Yount, at the California end, and Ben Best and Andy Zawacki at the Michigan end.

John Day, representing the American Cryonics Society, (ACS) and myself met Andy and Dan as planned, at the Best Western in Rancho Cucamonga, Friday evening, April 2nd. The Critical Care Research (CCR) people invited us and Mike Quinn and Chris Dougherty (from Suspended Animation) out to dinner. Mike and Chris had arrived a few days earlier and had spent some time at the CCR facility. After a delicious meal hosted by CCR, and some lively conversation, we agreed to meet the next morning at CCR’s facility at 7:30 AM.

We were met by CCR’s Sandra Russell, Mike and Chris arrived shortly, and also Mike Connaughton. Mike was a big help as he was part of the group from CryoSpan that placed the patients in the capsule a number of years ago. Andy started piping LN2 into the transport tanks he had brought from Michigan. When there was sufficient LN2 in the tanks, the workers started the slow process of removing the patients and placing them in the tanks.

The plan was for Andy and Dan to drive the truck with the two transport tanks with the patients, and John Day and myself to follow with the "back up" vehicle. The backup truck had one empty transport tank, and two full LN2 dewars. We had walkie talkie and cell phone communication between the vehicles. After all the patients were placed in the transport tanks and another dinner hosted by CCR, around 6PM we were ready to move out. After driving around five hours, we stopped at a very large casino just over the Nevada state line. The place had a parking lot the size of ten football fields, and was almost empty. Unbelievable as it sounds, they said they were "sold out."

After driving a few more hours, we found a motel that had just opened. Considering the hour, it didn’t matter that there were no keys to the rooms. We could lock the door, but from the outside, if we wanted to get back in, we had to go get someone from the front desk to open it! (Something about it being a new Motel, and there was a mixup in delivering the keys)

The next day, Sunday started uneventfully, although there was some confusion as to the time, between crossing time zones, and daylight saving time that took effect at 2AM that morning. By early afternoon, with Andy and Dan a few miles ahead we were on Interstate 80, chugging up a mountain when there was a thunderous noise from the engine compartment. The truck stopped dead in the road and although the engine was running it wouldn’t engage the transmission.. It was only because of John Day’s skillful maneuvering of the truck that we were able to roll back and off the road and on to the shoulder. I shudder to think how long it would take for someone to ram into us if we didn’t get off the active lane quickly. We told Andy by cell phone of our situation, and John Day urged Andy to keep going as the sooner the patients reached CIHQ, the better.

A few hours later we were being towed by a monster tow truck with a sleeper cab back to Salt Lake City. We stayed in a motel in the city that night, and the next day the rental company brought out a replacement vehicle. By mid afternoon, approximately 24 hours after our breakdown we were rolling again. Since we were a day behind Andy, he couldn’t use the LN2 dewars we had to top off the transport tanks. Instead he stopped late Monday at one of the LN2 depots he had previously made arrangements with, in an emergency.

So instead of providing back up, we, the "backup crew" had to be rescued ourselves, and for the rest of the trip while we kept in contact with Andy, he was always a day ahead of us, and arrived at CIHQ Tuesday afternoon, April 6th. We, in the "rescue" vehicle arrived late Wednesday.

We were at CIHQ just a few hours when Jim Walsh, CI’s Funeral Director delivered an insulated box with an Australian patient in it. It contained the body of a middle aged woman who had died of breast cancer. Andy remarked on its excellent construction and insulation, noting that despite 17 hours flying time, there was still enough dry ice to maintain dry ice temperature.

Mike Quinn had flown up from Florida earlier in the day. Around 8:30PM he, Ben Best, Dave Fulcher and Andy started removing the patients and placing them in CI’s cryostats. Bob Ettinger, John Day and I were observers. The job was finished by 11PM.

By 7:30 the next morning John Day was on a plane headed back to California, and Mike Quinn and I were on planes bound for different parts of Florida. For me, it was six days after I had left home.

MEET BRENT FOX

I have known of the concept of "suspended animation" since I was first exposed to it when I was about six years old. The Sci-Fi films Planet of the Apes, and Gene Roddenberry’s Genesis II made the biggest impact on me concerning the subject.

I learned about cryonics around 1978, after reading an article in Future Life magazine, and then realized that cryonics is the closest thing to "suspended animation" that there is available with today’s technology.

I have a Cryonic Suspension contract in place with the Cryonics Institute. I know that there is no guarantee that cryonics will work, but I will take my chances with cryonics. It’s certainly better than the alternatives. Cryonic suspension provides me with the possibility of reaching advanced medical aid for when the time comes that I will need it. Should cryonics work, the rewards will be unimaginable. I’d like to see the world of three hundred years or more from now. It will be quite an adventure.

I believe the biggest hindrance to the success of cryonics will be social issues and not technology. Will society continue to allow cryonics? Will society permit the revival of those in suspension? Will the human species even survive to the point where technology can accomplish revival?

Although my wife is not a cryonicist, she is supportive of my decision. My best friend probably thinks that I have read and seen too much sci-fi.

I’ve not yet had the opportunity to visit CI, or Alcor. I’d certainly like to go up to Michigan to personally meet Bob Ettinger. I would also like to head west and take a vacation out at David Pizer’s Creekside Preserve. I’d love to see the future site of Ventureville. I think David has a wonderful idea that would benefit all cryonicists.

About twelve years ago, I found out that there was a fellow cryonicist who lived in a neighboring town just twenty five miles away. We chatted on the phone a few times, but our schedules didn’t sync before he moved out of state. The Internet is a fantastic tool. I’ve bandied some email with Dave Pizer, Mike Perry, Rudi Hoffman, and James Swayze. It’s been wonderful to be able to communicate with such brilliant people who share similar beliefs as your own. James and I have even started, perhaps the first, cryo-chess match.

I am forty years of age. I have three years of college. I have several years experience in the law enforcement field, and now work as an investigator with a criminal prosecutor’s office in Georgia.

In my spare time I enjoy reading science fiction. My favorite authors are Arthur C. Clarke, Philip K. Dick, and Isaac Asimov. I also enjoy reading science fact, with emphasis on cosmology and quantum theory. I’m an amateur astronomer, who enjoys dragging the wife outside on cold winter nights to gaze at Jupiter or Saturn. I’m also a techno-computer geek who is trying to convince the wife that we really do need that ER2 home robot, or at least an Aibo.

QUICKIES

If I’d know I was going to live so long, I would have taken better care of myself.

Mickey Mantle (Thanks to Mike Quinn)

In a recent QUICKIES we reported on Americans poor hand washing habits after visiting a rest room. Now along comes a device that uses light scanning technology similar to that used in slaughterhouses that can make sure that hand washing zaps germs that carry deadly illnesses. The unit can detect fecal contamination and pinpoints on a digital display where more scrubbing is needed.

USA TODAY

Biotech crops is USA getting more acreage. The three genetically altered crops, corn, cotton and soybeans continue to garner more acreage-based on The Agriculture Department’s projections of grower planting intentions. The crops are engineered to do one of two things: to survive when doused with herbicides that kill surrounding weeds, or to resist bugs with insecticides they’ve been genetically programmed to produce.

Ibid

Vitamin C has been linked to reducing the physical and psychological stress on people. Those who maintain a high level of the vitamin do not show the expected mental and physical signs of stress when subjected to acute psychological challenges, and they tend to bounce back quicker than those with lower levels of the vitamin.

Good sources of vitamin C: all citrus fruits, green Kiwi, black current, papaya, strawberry, tomato, watermelon and guava.

Some causes of stress: Moving, death of close friend or relative, divorce, financial concerns, illness, job change.

Warning signs: Anxiety, sleeplessness, anger, sadness, mood swings, chronic fatigue, rapid heartbeat, unusual weight loss or gain. FLORIDA TODAY

PERPETUTIES

Quite often on CryoNet someone will write in about a subject that hasn’t been mentioned for a while. And sometimes this results in a torrent of responses. This happened recently at: Cryonics_Institute@yahoogroups.com, Except for CI Officers and Board members, initials are used.

"M W" wrote:

Hi Everybody,

I've been a life member of CI for just over a year but I have yet to enter into a suspension contract.

At this point I should also mention that I am an overseas member of CI. I presently reside in Australia but I am planning to move to London later this year. If all goes well, it is also my long term aim to try to retire to live in Michigan, if that proves to be possible in light of US residency restrictions on non-US citizens.

Anyway, at the present time I've started to make some plans that relate to preparing to enter into the suspension contract and I'd appreciate any advice that members of the group might be able to give me on a matter that I'm looking into. Any thoughts at all would be really welcome.

I want to establish a US-based legal perpetuity (most likely a trust will be the form of entity most suited to this) to which I will be able to will most of my assets at the time that I am declared legally dead. The purpose of the entity will be to hold my assets in trust and prudently manage my investments so that, hopefully, when re-animation occurs in the future, I will then have a reasonable financial start to my second lease on life.

After doing some internet research I am aware that some states in the US do permit the establishment of legal perpetuities but I have not got much further than that at this point. I do have an Australian lawyer looking into it and he has told me that it would be very helpful to him if he could be put in touch with a US law firm that has some expertise in this area. Any suggestions?

I'm sure that this issue must have occurred to quite a few members of the group previously and I'm sorry if there is some duplication involved in what I have put forward here.

Thanks for reading my message and, once again, I'd welcome any thoughts.

From "JR"

I'm looking into this, too. In my case, I managed to find the OLDEST law firm in the U.S. as I was looking for stability. It's Cadwalader, Wickersham, and Taft (www.Cadwalader.com). They were

founded in 1792 and are still in business. I'm not quite ready - financially - to proceed on it yet, but I hope I will be in a few years. They have offices in New York, London, Charlotte, and Washington D.C.

Ben Best wrote:

A perpetual trust would not be formed and funded with $100, although the pre-trust (more details later, if I get very

involved) might be. I would expect the minimum requirement would be

around $30,000.

John deRivaz replied:

Well, if each person had to put up $30k, then this would be a big drain on possible bequests to CI and I would be against CI helping to make this happen. It is also totally unnecessary in terms of what is needed.

What I think is a good idea is for many people each to put up $100 into a single trust and the trustees would distribute it in proportion when and if they are reanimated. It may well be that you'd need 300 people interested to make a trust of $30K and that is fine, but I would be surprised if enough appear by next June.

Because the sums involved this side of the dewar are small, no one should get too hot under the collar about issues such as What happens is the individual is not cryopreserved, not reanimated, or the funds end up being used to prop up CI in time of crisis. With 30k these issues would loom large, and rightly so.

Investing in technology (at present unpopular) since 1990 to date the rise is very approximately five times, or 12% per year compound. Obviously if you invest on top of a spike like March 2000 then it will be a long time before such a rise is seen, but the previous spike is not that far from 1990 prices as far as I can recall without looking it up. Cryonics relies on technology, so this investment will seem obvious to those who can experience themselves being reanimated.

$100 at 12% for 100 years is 100 x 1.12^100 = 8 million approx. It sounds a lot, but realistically is probably about $40k by today's standards for essentials.

But it would probably be worth 100 million in terms of things like computers and so on. The latter is a guess really because if you try to work it out based on the cost of a computer in the 1950s and today the number is so large as to be ridiculous. I noticed a VCR for sale for £50 in a mail order magazine today. The best possible machine cost £700 in 1970, but its quality was pathetic compared to the £50 machine today.

If you put $30k into these figures, the result is unnecessarily large. With 30k the loss to CI over the intervening period before reanimations occur could be catastrophic, and instead of hundreds of people with Gates-like fortunes there would just be hundreds of rotted or burned corpses.

Ben Best replied: Actually, John, my work with Brad Grossenberg was exactly what you described -- a template. I was Secretary of CryoCare and the plan was to create a template trust that all CryoCare members could use.At Alcor all of the Patient Funds go into a single pooled trust. At CryoCare the plan was for each member to have their own individual perpetual South Dakota trust -- there would be no pooling of funds. I found a South Dakota bank that would act as trustee and give us a special group rate on trusts -- so it would be very economical for the Members.

I was creating a family of template trusts, actually. There would be irrevocable and revocable pre-mortem trusts and, I believe, insurance trusts. Money from these trusts would flow into the perpetual post-mortem trust at the time of the death of the Member.

It was a great scheme, but CryoCare went down the tubes. I think that the trusts we created could be modified. If there is really a demand for this, I would possibly look at re-animating and modifying this project for the benefit of CI Members. However, I would not be able to pay for this out of my own pocket, as I did when I was with CryoCare.

Ben

"JB" wrote: Ben, I'd like to learn more about it.

Ben Best replied: OK, it appears that you and quite a few others would like to

learn more about it. So I will need to clarify a few points.

A perpetual trust would not be formed and funded with $100, although the pre-trust (more details later, if I get very involved) might be. I would expect the minimum requirement would be around $30,000. The trusts templates I was establishing for CryoCare were intended to provide the full funding of a Member in perpetuity -- allowing each Member to fund as much or as little as they chose above a certain minimum. For CI, if we set up a similar set of South Dakota perpetual trusts, they would have to be above and beyond the minimum funding requirements (ie, Option One $28K, Option Two $35K -- plus shipping and "handling" by a funeral director). CI Members would make CI the beneficiary of their insurance policies for the minimum funding requirements and then could make their personal perpetual trust the beneficiary of the rest of the insurance policy. Or South Dakota living trusts could be set-up which would have real equity which would have as their beneficiary the South Dakota perpetual trusts of the Members. CI would still receive the minimums in the usual way -- outside of the trusts.

I have just spoken to Brad Grossenberg, the South Dakota lawyer who helped create the CryoCare South Dakota perpetual trusts and he says he would be ready, willing and able to do more work on creating perpetual trusts for cryonics purposes.

I would be very pleased to work with Brad Grossenberg to re-work the templates we created five years ago to accommodate the needs and wishes of CI Members. However, your President is very busy and I would not want to begin working on this until at least June and probably later -- although well before the AGM in September

Robert Ettinger has frequently noted the value of being a benefactor to CI in addition to the minimum funding. The more people who are benefactors -- who leave substantial amounts of money to CI through their estate or (better) through an over-funded insurance policy (thereby avoiding probate) stronger CI can become. Money is energy, money is strength. The Also, bequests to CI show a benevolence to your fellow cryonicists -- part of a group of people working together for a common cause.

I would not want to encourage individual perpetual trusts if it is only going to mean a decline in bequests to CI. I would want to help create simple templates and a fiscal/legal structure for South Dakota perpetual trusts if it means more service to our Members, more options and more reason for people to want to be a part of our organization and to support it.

Ben

From "E N"

Why couldn't an investment account be set-up by CI, as a non-profit, to which members could make donations. A record of contributors and the size of their contribution could be kept by CI. Upon reanimation, CI could gift an appropriate sum to the reanimated individual. The pool of funds could be invested and returns reinvested in a technology index fund and managed by the CI board of directors. This should be easy as the only time a decision would have to be made would be if the fund closed down, merged or something else occurred that might necessitate identifying a new fund to which the investment could be moved. I would suggest placing the account with a brokerage firm and investing in an exchange traded fund (ETF) such as the Goldman Sachs Technology Index fund, which trades on the American Stock Exchange just like a stock. Of course, this would be another thing to be watched, i.e., the broker going out of business and CI would have to find a new broker. There is probably some legal issue here that I'm blind to, but I thought I'd throw it out.

Ben Best replied: For the most part, this idea appeals to me a lot. I like the idea of being able to offer services for our Members-- perks of being with CI. This idea would allow Members to contribute as much or as little money as they wish to their reanimation fund (perhaps a $100 minimum). Hopefully the administrative costs would not be too great. Withdrawals from the fund would be prohibited -- permanent contributions only-- just as the contribution of human remains is permanent. If Members can entrust their bodies to CI they should be able to trust money. The money would be invested in a technology ETF -- I would prefer QQQs rather than a fund attached to a single company like Goldman Sachs. There would be no capital gain because there would be no sales before reanimation. There would be no necessity of creating a formal trust if based entirely on "trust" in CI.

There has been considerable interest in this subject. It’ll be continued in the July-August issue.

DEANIMATION

Mr. Mole mentions deanimation and Oregon as sometimes allowing euthanasia. My own plans, probably in the not distant future, are along the following lines.

In Michigan suicide is not illegal, although assisting in a suicide is. Also, in hospice programs the red tape is much reduced. It should only be necessary to persuade the medical examiner, in advance, to have a representative on hand when requested, to pronounce death, after assuring himself that the patient is competent, and waive autopsy. Everything could be set up for the cryonics team to go to work immediately.

To prepare the way, it might be useful to mount a campaign to educate the public not only as to the potential benefits to the patient, but also to the families and public. If the last weeks or months of painful and degrading deterioration can be avoided, suffering by patients and family will be reduced. Then there is the money saved by the taxpayers.

Recently I spent two days in the hospital. That cost the taxpayers almost $14,000. (It also cost me $7.50, seven dollars and fifty cents.) Meanwhile, Medicaid is being cut back. (I don't use Medicaid; I use Medicare and Blue Cross, with VA also available, all paid for by the taxpayers, my Blue Cross being paid by the state of Michigan because I am a retired teacher.) Many voters are likely to believe that this money would be better spent on Medicaid, which is being cut back to save money and effectively denying much medical help to poor people, especially poor young people.

I will never go voluntarily into a nursing home. When it looks like I can no longer take care of myself, it's see you later alligator.  

Most of my projects will have to wait until reanimation, if they are then still relevant. Perhaps the only two projects realistically in the offing now are to finish a version of Youniverse and break ground for voluntary deanimation. I'll probably need some help with the latter.

Robert Ettinger

WHO’S BIG IN 2054?

Once a year FORTUNE magazine publishes their list of the 500 richest companies in America. This year, in addition to the regular list, they asked Peter Schwartz of Global Business Network to do some prognosticating about which firms will make up the top ten in 2054. Global Business Network has provided consultation services for many FORTUNE 500 companies as well as the CIA.

Regrettably there’s no cryonics company here, but there are a couple of companies that would interest cryonicists. Here’s a condensed version are his very educated guesses: (The full text is in the April 5th issue)

AmazonEbay. Amazon and eBay merged in 2015 to become the worlds largest Transaction Envelope Company. (TEC) The TEC would know everything about you , since the day you were born. In the vastly wealthier and universally connected world of 2054, most shopping for anything is virtual. In addition to being able to supply goods and services, it’s also provides banking, credit card and insurance services. Everyone would have their own digital shopper (DS,) a cross between a butler and a personal accountant which they could access any place, any time.

Your DS knows everything about you, your tastes, spending habits, even your financial prospects. It’s estimated AmazonBay’s transactions between it (a TEC) and DSs will gross 10 trillion dollars by 2054. Some of the smaller TEC’s are Bank of Wal-Martia and ProvidiPenny.

Toyota. Nothing too radical in automobile appearance, but under the hood things are very different. Propulsion systems vary from fuel cell to turbogenerators, and are much more powerful than today’s engines. Although the world’s population has stabilized at around eight billion, in each decade in the new century, both India and China have seen 100 million people climb out of poverty and into the market for a car. Recognizing the huge economic shift towards Asia, in 2024 FORTUNE renamed it’s list a "global" one and moved their main offices to Honolulu.

Sinogazzon. Created in 2025, it’s a merger of Exxon, Gazprom, a Russian gas producer and Sinogaz, a Chinese gas producer. Oil production peaked in 2035, and began it’s decline in 2040. At which time hydrogen derived from natural gas began to replace gasoline. Largely due to Exxon’s technological leadership, Sinogazzon is a world leader, with huge gas projects in Australia, Antartica and Qatar.

Sinobiocorp. Unlike the U.S. and Europe where people were skeptical about bio-enhancement, Asia embraced it. Vast aging populations in China, India and Japan created a market hungry for biological advances. Sinobiocorp, formed in 2010, is the world leader in drugs, agriculture and bioindustrial processing. After losing its economic leadership to Shanghai, Hong Kong has become China’s center of pleasure and high end living. Hong Kong has become the center for the most advanced health care in the world. With life spans pushing 150, Sinobiocorp provides services that include tissue regeneration to reverse aging, tissue realignment to reverse appearance, and complete cloning.

Indosoft. Not long into the new century, the American computer giants began to be dominated by their Indian talent. Over time the center of action moved from the U.S. to India. In 2030 Microsoft and Oracle merged, changed their name to Indosoft and moved their headquarters to Mumbai.

While world famous for their intelligence and competence, the Indian programmers are losing their jobs to artificial intelligent units (AIU,) causing the company’s management to wonder if at last they are in danger of putting themselves out of work. As more intellectual activities are taken over by AIUs, the debate on I-sourcing will increase.

IBM. In 2023 IBM introduced the BohrBox the first quantum computer for office use. Rendering today’s computer hard drives obsolete, bean sized capsules of gas can hold trillions of times more information than today’s computers. In 2035 IBM dominated it’s field by buying HP, which had acquired Intel a decade earlier.

Because of the endless drive for productivity, intelligent devices are imbedded in nearly everything and able to communicate with one another. Nearly all technology is accessible through voice recognition, in this new network marketplace IBM’s income is from "bit fees," a small fee for each bit of the unimaginably huge amount of data moved for it’s customers.

Pattelco. At one time an Indian software company, it bought the remnants of AT&T in 2025, and put the long distance company’s name into it’s own. At that time it launched the telepresence (TP) industry. Nearly every room, public and private, at home or at work, is now equipped with telepresence devices. TP makes virtual travel possible because of its ability to convey the experience of another location convincingly, and for people at the other end to experience you as present.

Nestle. Nestle dominates the field of nutriceuticals, the new class of foods that combines agriculture and drugs. The company focuses on "making well people even better." They have a new line of chocolate cookies with stem cell memory boosters, their frozen food meals are programmed to automatically lower cholesterol and dissolve trans fats. Their cosmetic division, L’Ore-All features a lipstick containing the recommended daily dose of 100 vitamins and minerals.

Nanobotix. Based in Palo Alto, Nanobotix has been the pioneer in manufacturing at the atomic level. Except for steel, cement and a few other commodities, most manufacturing is done using nanotechnology, the process of building anything molecule by molecule. In 2042 the company introduced its most advanced product, the desktop factory. Resembling an early laser printer, it has a transparent cylinder where the operator can see the object appear as the nano assemblers do their work. The prognosticators make no mention of the medical benefits of nanotechnology, which most people feel is the key to revival for today’s cryo patients.

News Corp. In 2010 this company led the trend in making all types of media available on demand-movies, newspapers, books, music. Its latest entry in ubiquicasting is the company’s media telepresence (MTP) service. For a substantial bit fee, advanced computer technology virtually embeds a person in an event or a situation.

As profitable as the service is, the company’s biggest revenue producer is the ownership of sports teams and their distribution rights all over the world. Rupert Murdoch, the firm’s CEO, who died in 2027, at the age of 96 spent the last ten years of his life entering everything he had ever known and as much of his persona as he could into a state of the art

IBM 2.4 petabyte quantum bubble array.

Insiders say Murdoch is now, if possible, even more of a force to be reckoned with for one simple reason---he never sleeps.

Apparently the prognosticators never considered that Murdoch might like to return to this life with the benefit of cryonics, instead choosing eternity in a virtual world.

LIFE EXTENSION NEWS

Vitamin E Absorption

Continued from the last issue

A glitch, the researchers say, is that vitamin E is an oil, and people are now being told to use oils very sparingly. It can be found in nuts, oily fish, some vegetables and oils such as safflower, olive and canola oil. The most common way that people get vitamin E is through rich desserts and cooking oils.

"If people are getting all the vitamin E they need through a healthy, balanced diet, that's great," Traber said. "But we really don't want to be telling people to eat more fat, and that's generally where vitamin E is found. That's why it's appealing to find an effective way of obtaining this nutrient, such as vitamin E fortification of what is essentially a low-fat food."

This controlled study was done by LPI scientists, funded by and in collaboration with the Bell Nutrition Institute of General Mills.

In it, scientists tested the results of four different types of breakfasts: a pill of 400 I.U. of vitamin E with skim milk; a serving of a wheat breakfast cereal fortified with 30 I.U. of vitamin E; a serving of wheat breakfast cereal fortified with 400 I.U. of vitamin E; and a serving of wheat breakfast cereal with a pill of 400 I.U. vitamin E taken separately.

The pill of 400 I.U. vitamin E taken with just a glass of milk, in theory should have provided more than 13 times the RDA of this nutrient. But, in fact, it raised the level of new vitamin E in the blood by only 3 percent. By comparison, the cereal fortified with 30 I.U. vitamin E raised the blood plasma level of new vitamin E five times higher than that, and the cereal fortified with 400 I.U. raised the new blood plasma level 30 times higher.

The effect of a pill of 400 I.U. taken with a serving of plain wheat cereal was inconsistent; some participants had a significant increase in blood plasma levels of vitamin E, others almost none.

"This study clearly showed that applying vitamin E onto a grain cereal provided a huge and consistent increase in its bioavailability," said Scott Leonard, an LPI research assistant who conducted the study. "Even 30 I.U., the RDA for this vitamin, produced a large increase in new blood plasma levels."

According to Traber and Leonard, this indicates that people who are taking vitamin E supplements only with liquids on an empty stomach are accomplishing nothing and getting few if any benefits from the supplements. The vitamin clearly is absorbed better if it is part of, or closely associated with the digestion of a food that has some fat in it.

Vitamin E has been explored in recent years for its potential value in prevention of heart disease, cancer, Alzheimer's disease and other health concerns. The results of this study may explain in part why the other research has often yielded inconsistent results, Traber said.

"It's now clear that vitamin E must be taken in a certain way to be effective, either in a food containing vitamin E or in a supplement properly associated with a food," Traber said. "So anyone studying vitamin E for a clinical response must now be sure they are using it in a regimen that works."

It may also be time to consider the expansion of vitamin E as a routine food additive, she said.

"In our pursuit of low-fat diets, we increasingly are taking the fat out of foods but not putting the vitamin E back," Traber said.

________________________________

Earth’s Easiest Exercise

Walking can add years to your life, and life to your years. And it couldn’t be easier.

The Conditioner Walking conditions your heart and lungs, and raises your body’s ability to use oxygen more efficiently. In one study, women who walked briskly (3-4 miles per hour) at least three hours a week, cut their risk of heart attack and stroke by more than half.

The Protector Walking helps beat other health problems, too. It reduces your risk of cancer and some forms of osteoporosis. It fights the battle of the bulge, taking off fat and building muscle. Walking can even help people with diabetes, reduce or eliminate their need for medication.

The Joint Saver Walking can burn as many calories per mile as jogging does. But it delivers only about a quarter of the jolt, so it’s much easier on your joints and muscles.

The De-Stressor Walking is easy on your mind, too, since it lessens stress and lightens depression. Beginning walkers usually report that they feel better, sleep better and that their mental outlook improves.

The Winner Best of all, walking has the lowest dropout rate of any form of exercise. So you’re more likely to stick with it and get all these benefits and more, like better digestion, improved regularity and lower blood pressure.

There’s Nothing To It! Just put on a sturdy, comfortable pair of shoes and go. Walk to the store for the paper,park a few blocks from work, or get of the train or bus one stop early and walk from there. Use stairs instead of elevators and escalators. On bad weather days, walk in a mall or on a treadmill.

How fast should you go? That’s easy, just use the "talk test." Move at a steady clip that makes your heart beat faster and causes you to breathe more deeply—but doesn’t leave you too breathless to carry on a conversation. Greenwise

_________________________________

Food Folklore

Folklore: An apple a day keps the doctor away.

Fact: Apples can combat cancer stroke and heart disease and help lungs. New Harvard research finds 20% less heart disease in apple eaters. In test tubes, apple antioxidants slowed the growth of human cancer cells 50%. The peel has the most antioxidants.

Folklore: Fish is a brain food.

Fact: Omega 3 fats in sardines, herring salmon and tuna make brains smarter, happier and less diseased. In new research, young adults who ate fatty fish were 20% less hostile than non-eaters.Older people who ate fatty fish at least monthly had 60% lessAlzheimer’s disease than non-eaters.

Folklore: Cherries cure gout.

Fact: Eating 45 Bing cherries cut blood urate levels (a sign of gout) 15% in women says University of California, Davis, research. Other signs of inflammation (including blood C-reactive protein) also sank.

Folklore: Eggplant helps hearts.

Fact: In studies, eggplant cuts cholesterol and discourages artery clogs. Now USDA scientists find eggplant flesh is packed with a potent antioxidant, chlorogenic acid, which fights bacteria, cancer, viruses and cholesterol. Eat the skin, it has antioxidants too.

Folklore: Cranberries prevent bladder infection.

Fact: Research says drinking 1 cup of cranberry juice three times a day for a year cut repeated urinary tract infections in women up to 50%. Concentrate tablets also work, but may increase the risk of kidney stones, Stanford University researchers say. Sorry, but in existing infections, cranberries don’t appear to help much. USA WEEKEND

NEWS ABOUT CRP

Like high blood pressure, internal inflammation does not exhibit any symptoms. Inflammation is produced as the result of body fat, which generates inflammatory proteins; and smoking, stress, and low grade infections like gum disease can also contribute. C-reactive protein (CRP) rises when blood vessels are inflamed, so blood levels of CRP are considered a reliable marker for inflammation and for predicting the likelihood of cardiovascular disease.

A new study in The Journal of the American Medical Association (JAMA) finds that CRP levels are significantly higher among people with macular degeneration, than those who don’t have this age-related vision problem. While some of the risk factors for cardiovascular disease are linked to macular degeneration, this investigation suggests that high levels of C-reactive protein may be an independent factor for macular degeneration---and that inflammation may be a possible cause of vision loss.

Inflammation also appears to be a culprit in colorectal cancer. Blood levels of CRP were higher among all colon and rectal cancer cases in a case control study of more than 20,000 adults in Maryland.

C-reactive protein levels fluctuate daily. Aging, alcohol use, coffee consumption, high triglycerides, hypertension, inadequate exercise, insulin resistance (and diabetes), sleep disturbances, taking estrogen, trans fats in processed foods can raise CRP levels. However, eating a whole foods diet rich in omega 3 fats, moderate wine consumption, and getting regular exercise can reduce C-reactive protein. Greenwise

_________________________________

WEB DIETS HELP DIETERS

Internet dieting has exploded in the last few years, attracting people who lack the time to attend meetings or don’t like to step on a scale in front of others.

One of the largest, eDiet.com has over 200,000 members. For $5 a week they receive meal plans and shopping lists and around the clock access to nutritionists and chat support rooms. Dieters are encouraged to keep a daily log of their daily food intake, and a weekly log of their weight. If they forget, a message pops up on their screen the next time they sign on.

Unlike traditional dieters whose progress is monitored by a dietician, online dieters are entrusted with keeping track of their own weight, which critics say may cause some to inflate their results.

A 2001 study by researchers at Brown University found that those who enrolled in a structured online diet program lost three times more weight in six months than those who casually surfed the web for diet information. FLORIDA TODAY

________________________________

FAT INTAKE AND BREAST CANCER

A new British review of current literature shows significant breast cancer risk from saturated fats and meat intake.

While researches found no significant relationship between overall dietary fat intake and breast cancer, women who consumed the most animal fat ( 23% of calories) from red meat and dairy products high in saturated fats had a 33% greater risk for breast cancer than those who ate the least saturated fats (12% of calories). In this study, there was no association between fat from plant or marine sources and cancer risk.

To help prevent breast cancer (and protect your heart), substitute omega-3-rich fish and plant proteins (like whey and soy) for animal fats. And whenever possible, choose certified organic foods produced without synthetic pesticides or growth hormones. Greenwise

_______________________________

CONSUMERS UNION LISTS THE "DIRTY DOZEN"

Even though they’re natural, some supplements may cause cancer, kidney or liver damage and even death. Some are banned in Asia, Europe and Canada, but widely available here.

They are: Aristolochia- kidney failure and cancer.

Yohimbe- heart and respiratory problems.

Bitter orange-similar to ephedra which is believed responsible for 155 deaths nationwide.

Also, chaparral, comfrey, germander, kava, and skullcap, all likely causes of liver failure.

Lobelia-possible heart problems.

Pennyroyal- possible liver kidney and nerve damage. USA WEEKEND

CRYONICS GROUPS WORLDWIDE
 
UNITED KINGDOM: There is a large, enthusiastic and active group that meets every month under the name CRYONICS EUROPE. Visit them at: www.cryonics-europe.org. Activities include discussion, CI standby team training, videos,and social events. All visitors, and new and prospective members are welcome! Please contact: Mark Walker, C.E. Membership Manager at davros@.... Tel.UK:01543-674129, Mobile: 07970-254948.
 
NETHERLANDS:

 This is a very keen and growing group anxious to expand. Contact George Overmeire at Giorgio@... or telephone +31-(0)6-51-454237

IRELAND:

Peter Thornbury and his wife are attempting to organize a CI group in Ireland. Peterhas homes in both the north and south of Ireland, and welcomes any contacts. He may be contacted by mail at: Peter Thornbury, 50 Lough Road, Lurgen, County Armagh, North Ireland. Email messages for Peter Thornbury should be sent via the UK group. (See above.)BELGIUM:

 A new website in Dutch and French is being setup for Belgian cryonicists. Contact David Verbeke at: davidverbeke@..., or email cryonicsbelg@... for further information.CANADA:

 This is a very active group that recently participated in Canada’s first suspension. President, Christine Gaspar, Vice President, Gary Tripp, Secretary/Treasurer, Ben Best. There is a sub-group called the Toronto Local Group. Meeting dates and other conversations are held via the Yahoo groups address: cryonicssocietyofcanada@yahoogroups.com

DENMARK: A new Danish support group has emerged and is online -- the Danish Cryonics Support Group. Contact them at: http://www.cryo.secureid.com, or at: david.stodolsky@...

JAPAN: Hikaru Midorikawa, President of the Japan Cryonics Association is attempting to reach to anyone living in Japan, and interested in Cryonics. He can be reached at:Hikaru@...

AUSTRALIA:

Theo Tatton, CAA’s Executive Officer advises us that the CAA has a bulletin board: Caa-list@... Their Public Relations Officer is Phillip Rhodes. They have an annual meeting alternating between Sydney and Melbourne. Their mailing address and phone number are: P.O. Box 57, Hampton Vic. 3188 Australia Phone 61-3-9-9589-6236ITALY

Am looking for contacts in Italy or Ireland who are interested in forming a Cryonics Support Group. Anyone with a knowledge of Italian law would also be very welcome. I was born in the UK, have Dual Italian/UK Nationality & speak both fluently. Please contact me in Cassino, Pr.Frosinone, Italy on 0039-347488-9679 or my house in S.Ireland (mainly Summer)on 00353-(0)87246-4538, Aldo Fusciardi

SPAIN

Giulio Prisco is Secretary of the Spanish Cryonics Society. He lives in Madrid .and he’s a life member of CI. and is willing to serve as a contact point for Europeans. He can be contacted at: cell phone (34)610 536 144 or gpmap@...


 
Small Print:

For more information about cryonics or Cryonics Institute and how to become a member, visit our web site at http://www.cryonics.org.

We encourage readers to forward issues to friends and interested parties. Please send any suggestions or comments to Long Life by emailing John@...

Long Life would like to thank Longevity Report, Wired News, InfoBeat, The New York Times, The New Scientist, Nanodot, Slashdot, contributors to the Extropian and CryoNet mailing lists, members of the Cryonics Institute, and others, for helping provide some of the free public information used in Long Life.

(Disclaimer: CI does not necessarily encourage or advocate the use of any products or practices mentioned in its newsletter.)


--
Sincerely, John de Rivaz: 
http://John.deRivaz.com for websites including Cryonics Europe, Longevity Report, The Venturists, Porthtowan, Alec Harley Reeves - inventor, Arthur Bowker - potter, de Rivaz genealogy,  Nomad .. and more

#29 From: "John de Rivaz" <John@...>
Date: Fri Mar 26, 2004 3:21 pm
Subject: Long Life vol 3 no 3 - Immortalist Highlights
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Long Life: the Cryonics Institute newsletter

March 2004 -- Volume 3, Number 2 - Immortalist Highlights

Welcome to Long Life -- the electronic newsletter of the Cryonics Institute. We're here to update you with brief cutting-edge news, updates, links, and information about the latest scientific, medical, health, anti-ageing, and social developments relevant to CI's goal of saving, preserving, and extending human life. Long Life may also include news about Cryonics Institute events and member activities and opinion. We welcome your feedback, and encourage readers to forward issues to friends and interested parties.

I would also urge readers to subscribe to the paper issue of The Immortalist (see http://www.cryonics.org/info.html ) as not everything is reproduced in this email version.

Editors Corner

News and Views

Conditions to Licensure as a Cemetery

Cryonics Friendly Countries

Hugh Hart's Generosity and Cryopreservation

Quickies

Life Extension News

Final Departures

CI Member Policies to Remember

Cryonics Mission to Mars

Death and Cryonics: A Case for Immortality

Cold Water Drownings

Two Davids

Long Term Personal Storage at CI


EDITOR'S CORNER

There aren't many perks that come with an editors job. (This editor anyway!) But over the years, we have received three. The first was an online version of The First Immortal sent by James Halperin.

Then a few years ago, the English publisher Hodder & Stoughton sent us Barry Albin's Don't Drop the Coffin. And now again thanks to Barry Albins literary efforts, we've received from the same Publisher, Final Departures, an appropriate title for an Albin project. It is billed as "Around the World with Britains most Remarkable Undertaker."

The Press Release that came with the book is in this issue. We have looked through the book briefly. The first three pages of the cryonics chapter sound like a CI ad. In fact they almost are word for word from the ad on the inside front cover of The Immortalist!

There are some morbid things like the fellow in Arizona who had his 29 year old wife embalmed at her death, and placed in a glass coffee table. There is a photo, presumably of the husband sitting on the couch, looking at "Lucy." There's also an interesting description of an automated Chinese crematorium that cremates 300 bodies a day.

As we mentioned previously, in the press release, there is only a two line mention of Alcor. The Cryonics Institute and CI are mentioned 32 times. Maybe the guy just loves us! While we are not going to lose any sleep over this, it seems as though any objective view of the cryonics movement in this country would not be complete without giving Alcor a little more mention, just as the same view would not be complete if CI were relegated to two lines.

In the chapter on cremation, he claims we have eleven states that have no regulations about crematories. If they view death so casually, perhaps one of these states would be a suitable home for Suspended Animation.



NEWS & VIEWS

President's Report

As readers can see, this issue of the Immortalist honors the late (and also, we hope, early) Hugh Hart who left most of his estate to the Cryonics Institute. Although Hugh was cryopreserved over a year ago, his estate was mostly in speculative stock, and its value has varied spectacularly during the period during which it was clearing probate. Hugh was devoted not only to his own cryopreservation, but to the "cryonics movement" and the potential opportunity of a greatly extended lifespan for all who seek it through cryonics. We honor Hugh for his idealism (our idealism) as he has honored us.

We have received most of the CI Member information update sheets that we mailed out to all CI Members. Unfortunately, too many of our Members have not chosen to join our Cryonics_Institute email list. This list provides a great opportunity for rapid feedback between CI Members and CI Management. Please send an email message to CIHQ@... and ask for an invitation to join the list if you are a CI Member and are not yet on the list. CI management mostly operates by email supplemented by phone calls and the occasional conference call. On February 22nd ten CI Directors and Advisors met in person at the CI facility to discuss and decideupon investment strategies. All strategies were conservative, but have good prospects for high yield. I hope to have such midyear (approximately six months from the Annual General Meetings in September) annually in the future and with a more general focus than just investment issues.

I am pleased to announce that The Immortalist Society (IS) is now able to accept credit card payment Visa, MasterCard and American Express. Payments to IS are mostly for subscriptions to THE IMMORTALIST or for research donations. If you would like to make a donation to cryonics research or have a regular deduction from your credit card for such donations please phone (586) 7915961 and give your credit card number. I am hopeful that CI will be able to offer CI Members the option of using Dr. Pichugin's vitrification solution rather than glycerol for cryoprotectant (antifreeze) perfusion within the next several months. Very favorable results have been seen in rats and in sheep heads. I hope to provide more details in the next issue of THE IMMORTALIST.

In this issue of THE IMMORTALIST a contract is announced between the American Cryonics Society (ACS) and Suspended Animation, Inc (SAI) which provides SAI standby services for ACS Members who want it. Vitrification service from SAI is expected in the near future. CI Members who want standby services from SAI can arrange for those services in addition to (and outside of) their arrangements with CI for cryopreservation.

I have asked that a special page be added to every issue of THE IMMORTALIST to emphasize CI policies of importance. Notably, I am especially concerned about the number of CI Members who fund at the minimums ($28,000 Option One, $35,000 Option Two). The minimums do not cover Funeral Director or shipping services, which can amount to several thousand dollars depending upon how far from Detroit the Member lives. Moreover, minimum funding provides no safety against future eventualities, uncertainties and opportunities.

The February 17, 2004 issue of USA TODAY contains a statement from Michigan Bureau of Commercial Services Director Andrew Metcalf verifying that the SPORTS ILLUSTRATED story about the cryopreservation of baseball star Ted Williams by Alcor was the impetus behind the Cease & Desist Order imposed on the Cryonics Institute which led to our licensure and regulation as a cemetery.

With the lifting of the Cease & Desist Order, cemetery licensure has not compromised CI service to Members and may well provide a sense of security for some.

FLORIDA RESEARCH LAB MOVING ALONG

Governor Jeb Bush, educators and politicians recently broke ground on a temporary facility to house the Scripps Research Institute in South Florida. As we mentioned in the last Immortalist, and reported recently in FLORIDA TODAY, Bush hopes the center will ignite biomedical development in Palm Beach County, and grow to duplicate the huge facility in San Diego, California.

A $12 million, 40,000 square foot lab is being constructed on Florida Atlantic University's Jupiter campus. The building will be used until it's permanent home is built in 2006 on the Institute's 1900 acres. The Institute has hired Charles Weissmann, an internationally known Swiss scientist, and mad cow disease expert to lead it's Florida biotechnology center. The first research teams are expected to arrive this summer.

ARIZONA MOVES TO REGULATE CRYONICS

On March 8th 2004, the Rules committee of the Arizona House of Representatives approved a bill that would regulate the cryonics industry (effectively Alcor) in Arizona. In a message sent to all Alcor members, Joe Waynick, Alcor's CEO/President, explained that the bill is still a work in progress. He also emphasized that when members contact legislators to express their views, they must treat the lawmakers with respect, something that a few members failed to do.

"If you don't feel you can calmly and respectfully state your case, then you should not contact the members of the legislature at all. Alcor once again owes Representative Stump, the bill's sponsor, an apology for the unwarranted actions of a few."

LONG TERM REFRIGERATED STORAGE

Those who are intereested in longterm storage of memorabilia possibly to assist reconstruction of identity in the far future in a secure location might be interested in doing so in a limestone mine under a mountain near Kansas City. I understand the charge is $6 per banker box and that storage for 100 years or more can be arranged at refrigeration temperatures.

Ben Best

Its web site is: http://www.uvsinc.com/index.html

CRYONICS IN THE NEW YORKER?

Yes, it's true! In the January 19th issue, one of the premier magazines in the country carried a fivepage article written by Alec WilkinsonTHE CRYONIC CASTLE. While the piece focuses mainly on Stephen Valentine and the TIMESHIP PROJECT, Bill Faloon and Saul Kent's proposed cryonic storage facility, what's striking is that nowhere is there any mention of "weird or crackpot science" or brains turned into hamburger. Wilkinson describes the proposed building B"and nearly fifty thousand people who have been frozen in the hope that they can be brought back to life in the future."

Just another example that cryonics is slowly creeping into the public consciousness.

Our thanks to Curtis Henderson for giving us a "heads up" on this one.

ACS & SAI SIGN LANDMARK CONTRACT

ACS and SA recently signed a contract that enables ACS members to gain access to the Standby Based Transport and cryosuspension services of SA, using a master ACS contract. SA is a cryosuspension research and services company located in Boca Raton. Florida. The contract gives ACS members the option of having SA perform standby, transport, and suspension services on a subscription basis. The contract also makes provisions for last minute signup with SA. ACS members who do not elect to designate SA to perform these services in advance may still benefit from SA services through an emergency subscription provision initiated through ACS. However, in cases where the member has not opted for SA service prior to a critical situation, SA charges a last minute signup fee and may give normal subscribers first priority.

SA is setting up a fully equipped research and suspension laboratory in South Florida. They provide a "traveling team" with mobile equipment that can be flown to a location anywhere in the US (and in some cases other countries). SA does not use a volunteer system but employs its research personnel to provide both transport and suspension activities. ACS also has mobile equipment, but we prefer to use our equipment and personnel in a backup capacity and intend on calling on SA to provide our primary suspension services. SA will probably charge a yearly fee of about $150 for its ACS subscribing members; this is in addition to the $300 per year ACS dues. This combined dues and fee schedule compares favorably with other fullservice plans. SA already has a 24hour emergency number that ACS members can contact and will establish a regular program of member contract and tracking to ensure they are prepared to quickly react to patient needs. Already one ACS patient is in their monitoring program. Research efforts at SA are focused on preventing, minimizing, and mitigating presuspension ischemic damage and on using vitrification techniques to obtain the best possible cryosuspension on the whole body level. Their longterm goal is reversible whole body vitrification. They are employing the vitrification techniques and biomedical discoveries of the Southern California biotech company 21st Century Medicine (and its associated research companies). One of the founders of SA, Bill Faloon, is also a founder of 21st Century Medicine. Dave Shumaker, President of SA, is an ACS member of long standing

Suspended Animation, Inc. is a wellfinanced company with access to cuttingedge research through its unique relationship with its affiliates. We are pleased to be the first cryonics organization to have a service contract with SA.

Jim Yount

ROBERT ETTINGER'S NEWEST BOOK

Before the end of 2004, I hope to contract for my new book, YOUNIVERSE, with a publisher or agent. All previous philosophers have been failures at best, and sad clowns at worst. Many of them were smarter than I, and some did useful work, but none came within shouting distance of the primary goal of philosophy, which is to provide guidelines for real life, especially life in the face of death.

Times have changed since I sold my previous books, and in order to interest a major publisher, it will help if I can guarantee a significant number of sales, so I make the following request and offer:

Readers are asked to remit $30 to the Cryonics Institute by Visa, Master Card, American Express, PayPal, or check. This will reserve a copy, to be autographed and delivered to you upon publication. Mailing address for the Cryonics Institute is 24355 Sorrentino Court, Clinton Township, MI. 48035.

If I contract with a publisher this year, the Cryonics Institute will turn over the prepayments to the publisher, and author's royalties for all prepaid copies will be donated to the Cryonics Institute.

If I don't find a suitable conventional publisher before the end of the year, we will go to an electronic print on demand system, and publish that way. In any case, your copy is guaranteed.

It will also help if I can get reviews from appropriate people with professional qualifications or name recognition. If any such request it, I will email a copy of the current draft, on his promise to provide a review suitable for publication, reasonably promptly, with permission to use it as I see fit.

There is, of course, no requirement that the review be favorable.

Finally, if you have any interest in this project, you could forward this or mention it to such people or locations as you think useful.

R.C.W. Ettinger

Ettinger@...

THE FIRST 50 PATIENTS

We are currently "processing" our 51st cryonics patient at CI. I am a statistics buff, so recently I created a database of patient information from our patient files and did some "datamining" to see what I could learn.

One observation that standsout is the fact that exactly half (25) of the patients are female and half are male. This contrasts sharply to the fact that only just over one fifth of CI members are female. When a child chooses to cryopreserve a parent, it is usually the mother. When a spouse chooses to cryopreserve a partner, it is usually a husband cryopreserving a wife. The age distribution (at timeof deanimation) of the patients is:

unknown

1

28

1

40s

3

50s

6

60s

4

70s

17

80s

12

90s

5

100

1

The 28 year old was the victim of an accident of suicidal recklessness and was cryopreserved by a parent. There were two murder victims. The rest died of the usual nonviolent causes heart disease, cancer, infection, etc. The major occupations were:

homemaker

6

teacher

5

professor

3

engineer

3

physician

2

And there was one each of lawyer, dentist, flight attendant, bill collector, garage mechanic, jewellery saleswoman, general laborer, park keeper, etc. Six of the patients are being stored for the American Cryonics Society. Country of deanimation can be classified as:

USA

42

Australia

3

Canada

1

France

1

Germany

1

Norway

1

Undisclosed

1

The number of Australians is striking insofar as they constitute 4% of our members, in contrast to the fact that no patient is from England where we have 10% of our (overseas) members.

FROZEN DEAD GUY DAYS FESTIVAL

This will be the 3rd year for the festival, held in Nederland, Colorado on March 13 and 14. Attendance seems to be growing every year, last year 5000 people attended, twice the attendance the first year. The centrepiece of the celebration is Bredo Morstel who died in 1989, and has been stored in a TUFF shed in Nederland since 1993 under a mountain of dry ice.

The driving force behind the festival is Morstel's grandson Trygve Bauge, a Norwegian who was deported from this country a few years ago after living here for fourteen years without a passport, visa, or green card.

Bauge has been urging CI and Alcor to set up booths at the site. Neither organization appears interested, perhaps because Bauge himself refers to the event as the "Mardi Gras of Cryonics," Or perhaps it's the "Frozen T shirt contest," the "Granpa look alike contest, or the coffin races?"

SUSPENDED ANIMATION REJECTED

Suspended Animation's (SA) building permit is rejected by Boca Raton City Council.

January 13, 2004, brought what seems like another blow to the Cryonics industry. But receiving a negative response from the Boca Raton City Council on their request for a building permit does very little in hampering the Cryonics movement or the company itself. The company continues to be ready with its Remote Transport Service to support members of cryonics organizations anywhere in the world. "We are a global support organization and this is only a small hiccup in the long road to making cryonic suspension services available worldwide." says the company's CEO, David Shumaker. "We've already finished what we needed to do in this facility through the completion of our remote kits. We are currently supporting cryonics members outside of Boca Raton and will continue to do so." He added.

TED WILLIAMS' SON DIES

In the last issue of The Immortalist, Jan.Feb 2004, we reported that the son of baseball great Ted Williams was diagnosed with leukemia, and that the prognosis was "not good." On March 6th FLORIDA TODAY reported that Williams' son died at UCLA Medical Center in Los Angeles. In December he underwent a bone marrow transplant, using a donation from his younger sister, Claudia.

Williams, 35 was at the center of a controversy last year because of his decision to have his father frozen. Ted Williams is believed to have undergone a neuro suspension at Alcor's Arizona facility. Funeral services for John Henry were reported to be "private." At the same time FLORIDA TODAY claimed to have a copy of John Henry's Will, in which he states his desire to have his remains sent to Alcor. This will tend to mute some of the criticism of John Henry from those who claimed he was capitalizing on his father's death for financial gain.

PHILADELPHIA SCIENCE FICTION CONVENTION

I had previously mentioned that I would be at the Philadelphia Science Fiction I had no inclination to say more, but a couple of people have asked about the outcome, so I will give a "report". It was not a surprise to me, but my cryonics presentation was sparsely attended 8 people out of just under the thousand or so attending PhilCon. Many of those were already very familiar with cryonics. Perhaps because my expectations were low I was not too disappointed. I do think most people learned a few things.

The Nanotechnology panel was dominated by a fellow who has been a Foresight Institute employee for ten years. In my introduction I mentioned being President of the Cryonics Institute and described relevant sections of ENGINES OF CREATION, while waving a copy. I was able to make a few comments about the Drexler/Smalley debate, but was otherwise not unhappy to be eclipsed by a person who clearly had much more knowledge.

His interests were extremely technical and unrelated to cryonics or nanomedicine.

But being a Foresight employee he was clearly aware that the powersthatbe take an interest in these subjects and he made a single comment which was the verbal equivalent of a polite bow.

I was able to have myself added to the "Suspended Animation, Then What?" panel. Just before the session Lee Gilliland (wife of Alexis Gilliland) "drafted" Keith Lynch to join the panel. One of the other panelists was an Alcor member which left the six panelists apparently evenly divided between pro and anticryonics sentiment although the Alcor member had his share of fears about the future.

The audience (about 20 people) was also divided. It was actually quite a confrontational & lively session pleasantly challenging. One of the other panelists was a professional politician from Washington, DC who seemed to think that cryonics would only populate the future with rich people (ie, social undesirables). He was not moved by my arguments about life insurance, but he was favorably impressed when I mentioned that James Swayze is a paraplegic living on welfare who has been funded through donations. At least one cryonicist in the future will be up to his standards.

Benjamin Franklin is a cultural icon in Philadelphia so I didn't miss the opportunity to describe Franklin's desire to see the future. Frankly, I think that within a month after being reanimated Old Ben would be on the internet writing critical essays about MicroSoft products.

The moderator of the panel, Ian Randal Stock, is the Publisher/Editor of ARTEMIS MAGAZINE.  He presented a steady stream of dystopian visions of the future which I countered with a steady stream of positive visions. At the end of the panel he expressed his displeasure at the lack of imagination about the future. At that point I figuredout what he was up to positive visions of the future amount to a "happily ever after" story which would be fictionally uninteresting. He assured me that he is not anticryonics and in support of this claim he showed me a favorable article Solid State Biology in the Winter 2003 issue of ARTEMIS.

Keith Lynch mentioned that Larry Niven had been in the audience (I hadn't noticed). Over 25 years ago Niven wrote a novel A WORLD OUT OF TIME about cryonicists reanimated in a dystopian future who ultimately triumphed.

This is actually the theme of the only novel I have ever been motivated to write, although my novel would be more of a cryonics propaganda piece. The cryonicists would be treated with contempt by their mortalist masters and there would be lots dialogue involving deathist & antideathist ideology. Naturally, the cryonicists would ultimately triumph through their love of life, passion for survival, longevity and technical ingenuity while winning a few notable hearts, minds & genitals in some torrid romantic & sexual passion. I have abandoned hope of ever writing such a novel I have too many projects with much greater priority but others are welcome to take the idea and run with it

Ben Best

SUSPENDED ANIMATION ANNOUNCEMENT

Through an exclusive agreement with Michigan Instruments, Inc. of Grand Rapids, Michigan Suspended Animation is proud to accept delivery of their first updated Dual Action Thumper. "This Thumper is far superior to the others on the market because it is easier to use, lighter, more transportable, and much more quiet and efficient.

"We've been collaborating with Michigan Instruments for months on this new design and we're happy to be not only the first company to have one but the sole distributor to the cryonics industry for this device. Our engineers have been in discussions and many meetings with Michigan Instruments and we've created the best there is." say's David Shumaker the companies CEO.

This device is designed to be a stand alone unit with a back plate but also adapts itself to attach directly to the Portable Ice Bath used on Transport Services. This means that our Standby Team has far less heavy and cumbersome equipment to manage at a patient's bedside enabling us to provide the best service in the industry.

The unit is approximately 40% lighter than previous models, and almost 80% less noise is created when in use. David Hayes, the companies COO states that "On a Standby there is always the concern of how much equipment we have and how noisy we are going to be once we begin working on the patient.

With this device we will be much less obtrusive to the hospital when we begin our Transport Services." He adds, "It is also one of the few in use that provide not only compression of the chest for blood flow and respiration but also decompression. Something that is vitally important to the proper oxygenation of a patient. It is also one of the few devices on the market with built in intubation respiration at the American Heart Association recommended 5 compression strokes to 1 respiration cycle. The compression piston is adjustable to fit body sizes from children to extra large adults."

This device is marketed through Suspended Animation, Inc. to the Cryonics industry and can be purchased directly from their website. The price is $7000, but Shumaker said if they can give Michigan Instruments an order for ten, they can sell them for $5000.

CSC CHRISTMAS PARTY

I wanted to let everyone know that the Cryonics Society of Canada Christmas party, held at my apartment, was a huge success.

It started at about 4 pm, and the last guests left at 1 am. We had about 23 people come, many of which were newcomers friends of CSC members, and one man who emigrated from India 2 weeks ago, who is a transhumanist, with a serious interest in cryonics. It was standing room only at times through the evening. I think we gained 5 new members to the CSC group last night, which is terrific.

My labours at preparing food weren't in vain, as there was very little left by the end of the evening which was great as I dreaded the prospect of having "leftovers" to contend with that would have likely lasted until the end of January. It took me about 16 hours to prepare everything, but I enjoyed getting the opportunity to throw such a party for this bunch of people. I haven't cooked for anyone in a long time., as I have been on my own since August. (referring to Andrew's departure)

Ben Best brought a treasure trove of books, that were put on display in an adjoining room. I was able to get a hold of about 7 or 8 of them, before the selections got too lean. I'll let Ben report on how many books he was able to sell, if he feels inclined to do so. The remainder will remain stored for him, in my apartment, with the rest of the CSC equipment which has found its new home here too.

Let me try and remember everyone that attended:

Ben Best, Brent Erskine and Irene

Martha Olijnik, Stan Witkowski

Gary Tripp, Rudy Matic, Bob Skakie

Doug Quinn, Adrianna Baranyai

Bruce Waugh, Tony Taylor, Ahsan Rashid, Keith Henson and Arel Allan Randall, and his parents who were visiting from Nova Scotia Dennis the transhumanist from India...sorry I don't know his last name My parents, Jack and Maria Gaspar

and me

If I have forgotten anyone...sorry about that.

I had another agenda too, in that I wanted my parents to meet all of the CSC people, and vice versa. When I started expressing an active interest to them about cryonics, they weren't exactly supportive of the idea. Well, I have been working on them for the past couple of years. I can be very stubborn when I want to be...and I think they are at the point now where they'd like to be suspended too. It was great fun to see my folks partying with the Canadian cryonicists and they really enjoyed it too.

I also got a chance to show everyone the finished copy of the interview I did, for TV, that will be aired on Global TV, on the 1/2 hr science and tech show "TKO" sometime in the new year. I think it was a very positive portrayal of cryonics on the part of the media, albeit a very brief spot on their show (2 minutes tops). It was also my first experience talking about cryonics on TV one which I learned quite a bit from.

I look forward to our next function, and hopefully all of these people will be able to attend, and more too. I did get regrets from several invitees, due to the time of the year when this was held, so potentially, there could have easily been another 5 people there at least...always working on next time though...

I want to thank everyone who came, for their interest, their energy, and for making the evening such a success. The CSC is an incredible organization of people, and this little group of ours is getting bigger and better all the time. I can definitely see that our group cohesion gets stronger all the time We have within us a huge potential to make cryonics great, which will impact everyone, everywhere, at some point in the (near) future.

Christine Gaspar


Conditions to Licensure as a Cemetery

Below are the Conditions to Licensure as a Cemetery which David Ettinger negotiated with Department of Consumer and Industry Services of the State of Michigan. This is version 7 of the agreement the final version which was accepted by both parties. This is a document of public record of which I believe CI members should be fully informed. It allows us to continue our operations in much the same manner except for the establishment of a separate fund and the requirement that we perfuse at a funeral director's establishment (whereas previously we had often perfused at our facility). So we are able to operate as a very special kind of cemetery with our own special conditions of operation, ie, we are fully operational as a cryonics organization.

Ben Best

 

CONDITIONS TO LICENSURE

The application for licensure for the Cryonics Institute ( CI ) is conditioned on the following facts, and licensure will

constitute approval of its operation in the following manner. Without waiving its claims and objections regarding the

lack of jurisdiction of the Department of Consumer and Industry Services or the Cemetery Commissioner over CI,

CI is prepared to accept licensure as a cemetery if the conditions are consistent with CI's method of operations

as spelled out below:

1. CI will engage in cryonic suspension and cryonic storage of its patients, as defined in its Cryonic Suspension Agreement, at its facility in Clinton Township, Michigan, except that any perfusion of patients with cryoprotective solutions utilizing current technology and conducted within the State of Michigan will occur at a licensed funeral establishment conducted by a licensed mortician. CI will not specify in advance the specific location within its facility at which any particular patient will be stored. CI will not require down payments in connection with its contracts. None of CI's facilities will be considered an undeveloped cemetery area. CI's services do not involve grave memorials or burial vaults.

2. CI will continue to contract with patients for the entire cryonic suspension process, including perfusion, and will make separate payments to funeral directors for the conduct of perfusion with cryoprotective solutions in Michigan.

3. CI shall require that funeral directors engaged in the perfusion process for its patients shall follow CI's protocol and utilize the chemicals directed by CI.

4. CI shall operate from a facility with the total property substantially less than forty acres.

5. CI shall set aside an Endowment Care Trust Fund containing funds equal to $4,000.00 per patient, for all patients cryonically suspended prior to the date of licensure, according to the terms of the attached Trust Agreement. These funds will be set aside for maintenance, which shall include liquid nitrogen storage of existing CI patients. All patients cryonically suspended postlicensure will have endowed care trust deposits of not less than 15% of the interment proceeds (defined as CI's minimum suspension fee less the amount allocated for initial expenses, including perfusion and initial freezing). The initial deposit to the Endowed Care Trust Fund shall be made not later than January 7, 2004.

6. CI will set aside funds in the amount of $50 per patient in a separate bank account for these patients who have chosen to prepay their suspension fees. Based upon its current operations, CI will not set aside funds in any other separate accounts, such as merchandise trust accounts, and is not currently subject to the Prepaid Funeral Contract Funding Act. Based on its current operations, CI shall not maintain a merchandise trust account, a cemetery development fund, a merchandise escrow account, a construction trust fund, or a construction development trust fund.

7. CI will not permanently seal its cryostats, but will continue to replenish them with liquid nitrogen and open them as appropriate, including to add patients. CI's cryostats will continue to contain multiple patients. CI s patients shall be required to use CI's cryostats. CI will not file a plat or map with regard to its facility, but will file a floor plan identifying the location of its cryostats, and will maintain records identifying the cryostats in which each patient is contained.

CI will not provide information to prospective patients regarding the specific cryostat which shall be utilized for them, and shall routinely contract with members for cryonic suspension without specific provisions for construction of cryostats for those members, since the death of those members could be years or decades in the future. CI shall not utilize grave markers, section markers or survey markers.

8. CI will continue to offer to its members the option of funding their cryonic suspensions by life insurance policies with CI as the beneficiary.

9. CI's facility received zoning approval when it opened, but CI is not zoned as a cemetery and will not be zoned as a cemetery.

10. CI will engage in a cool down of its patients according to its own best judgment of what is appropriate for its patients, and shall not be required to place patients in its cryostats as soon as possible after receipt, or obtain written permission for any delays in doing so.

11. Because of the uncertain, long term nature of cryonic suspension, CI shall not be required to indicate or assure how

it will perform its future obligations, or the cost of those obligations other than the cost of liquid nitrogen storage.

12. CI shall not submit its Cryonic Suspension Agreement to the Commission for approval because that document has been reviewed by the Commission.

13. This application has been reviewed by the Cemetery Commissioner and the Department of Consumer and Industry

Services, and they have concluded that CI's operations and the activities as described herein or as reviewed by them in their investigation of CI do not violate Michigan law and will not be the subject of enforcement action. Upon approval of this application the two Cease and Desist Orders dated August 26, 2003 shall be withdrawn.


CRYONICS FRIENDLY COUNTRIES?

Since CI, Alcor and Suspended Animation have been facing legal problems of one kind or another from governing authorities, there's been some speculation on Cryonet about other countries that might be more cryonics friendly.

From James Hughes, MD

After noting the terrible and, yes stupid, controversy about a cryogenic

physical plant, in either Russia or the US, it occurred to me that there is a

stable, libertarian government entrenched in the Dominican Republic. The area has enjoyed increasing stability lately with a boon in tourism and expats from Europe and the US. It is a "handsoff" government. The country is easily accessible from both Europe and the US and geologically stable. This may be a plausible location to consider.

From David Stodolsky:

"Randy"wrote:

I personally think that exploring how it might be possible to lobby in Russia would be a good idea. I also suspect that some countries like Japan and Korea would be amenable here.

If cryonicists could just get 35 countries to firmly legalize cryonics, this would be a big step forward.

I am thinking that if any country would be able to legalize cryonics,it would be one of the northwestern European countries, such as Switzerland, Netherlands, Denmark, Norway, etc. they seem to have a more pragmatic, nonreligious approach to life. For example, polls show that far fewer citizens of those countries have a belief in a god or afterlife (I think the figure there is maybe 3040% or so, as opposed to 6070% here in the USA).

These figures can be misleading. For example, even though belief in god is low in Denmark, as is church attendance, about 90% belong to the State Church. From a social psychological standpoint, this indicates such a deep integration of religion into daily life, that the weekly reaffirmation is hardly needed.

When cloning first became controversial, Denmark passed a law banning it immediately. Somewhat latter, it became apparent that cloning of cells, etc. was obviously a good idea, and the law was modified. Members of the official Ethics Advisory Board make statements about the need to improve the Quality of Life as opposed to increasing the Quantity of Life.

When I mentioned cryonic suspension to my MD, who is was willing to work with me on developing a drug regime for life extension, he said it wouldn't be long before a law was passed against cryonics, if it was attempted in Denmark. On the other hand, fetal cord blood is now routinely placed in low temperature suspension upon birth, in order to be available for cancer treatment.

The advantage of these countries over Russia, Japan, Korean, etc. would be primarily due to very low levels of corruption and a functioning legal system. However, the above argument could also be made.

Also, Switzerland and Netherlands have, I believe, practically decriminalized euthanasia.

The Northwestern European countries are all predominantly Christian, but there are significant differences in their responses to endoflife ethical questions. The European Values Study database could be analyzed in order to identify the best bet. However it might require a supplementary survey specifically on the question of cryonics to get specific results.

David S. Stodolsky

From: David Pizer

Someone asked "Which country is cryonics legal in?" Its legal in the United States!

There have been court cases in California where the judge ruled that death certificates have to be issued to cryonics patients and that cryonics could continue even though there is no "cryonics" box to check on death certificates. Thank you Judge Munoz.

In Scottsdale Arizona, the Mayor of the town welcomed Alcor's president when we moved here, invited President Bridge up to his office and had a nice conversation with him. The local hospitals and hospices treat Alcor in a professional manner. Things in that respect are not so bad for cryonics right now as the media might want people to think.

The real problem lies in the future when bioethic movement leaders try to outlaw cryonics. In the meantime they are trying to outlaw things that reanimation of cryonics patients will count on, like cloning human body parts.

We need to plan for the future. Moving from USA is not an option at present unless someone was willing to risk several million dollars for start up and continue to risk a slow growth for a decade.

Most cryonics members are citizens of the USA and don't want to be stored in a foreign country. That may change someday. It would be good for the movement for several groups to start up in different countries, but there is a lot of financial risk to that. Remember, those of us who helped start or develop the cryonics companies did so not as a good financial investment but because no one else wanted to do it.

I believe that there are ways to make a profit in the cryonics business but no one is doing it right now.

David

Charles Platt gives us some perspective

I see that Cryonet is going through one of its half baked phases. These always last longer than would seem possible.

Regarding the relocation of cryonics in some other nation (a halfbaked idea that has been raised periodically for more than a decademaybe more than two decadeswith no actual results whatsoever), I will take this fantasy a little more seriously if I see a minimum of 5 (five) cryonics activists actually making serious plans, supported by serious money, to move to any other nation and commence operations there. I will take it more seriously still if I see even 1 (one) possibly terminal patient express serious intentions to move to any nation that is considered more friendly to cryonics than the USA.

Bear in mind that historically, it has been difficult to persuade terminal patients to relocate near a cryonics facility *within* the USA (not impossible, not unprecedented, but difficult). People do not like to die thousands of miles from their home, family, and friends, and who can blame them?

Also one might consider that in Britain, where a substantial number of cryonics activists are located, there is still no fully equipped facility (no storage, for instance) and the capability that does exist was put together largely through the generosity and engineering skills of just one man (Alan Sinclair). I'm not belittling the help that Alan received, which was substantial. I'm just saying that without his capital and initiative, I doubt it would have happened.

Starting a cryonics organization is as tough as, or tougher than, starting any small business which requires substantial capital, skills, and labor. In fact, cryonics is unusually laborintensive, requires an exceptional range of skills, and of course never makes a profit. Relocating such an operation in a foreign country just multiplies the difficulties.

All of this, needless to say, should be INCREDIBLY OBVIOUS,and the pieinthesky theorizing about establishing cryonics in other countries is at best a doubtful use of one's time and at worst is actually deleterious to the provision of cryonics services in this country, since it distracts us from the hard problems and intense needs that we have here. I don't think it's coincidental that the wishful thinking has coincided with a time of exceptional challenges among US cryonics organizations.

How lamentable that instead of addressing these challenges there is an impractical yearning to get away from it all by going someplace else.

This reminds me of space enthusiasts who imagined that their social dysfunctionality could somehow be accommodated in L5 colonies.


Hugh Hart's Generosity and Cryopreservation

by Ben Best

Hugh Hart, who had been a Member of the Cryonics Institute for over a decade, died in December of 2002 and was cryopreserved by the Cryonics Institute. Hugh had never been married and had no children. Hugh was a Phi Beta Kappa who had taught mathematics for 16 years. Although He died at the age of 75, he was still working fulltime as a Counselor for a Pension Fund.

Cryonics was an important part of Hugh's life. In 1994 he wrote a letter to

Robert & Mae Ettinger in which he said, "My enthusiasm grows every time I'm able to help the movement." In support of the cryonics movement, Hugh left his entire estate well over $200,000 to the Cryonics Institute, with the exception of $10,000 given to his friend who served as the Executor of his estate. Hugh was a longtime subscriber to my magazine CANADIAN CRYONICS NEWS. In 2001 he gave $500 to the Immortalist Society to pay for gift subscriptions to THE IMMORTALIST and gave an additional $1,000 in 2002.

At the September, 2001 Annual Meeting of the Cryonics Institute Hugh made an impassioned speech about the danger of procrastinating cryonics arrangements. A friend of Hugh's who had long expressed interest in cryonics, but had never gotten around to signingup, had recently died.

Yet Hugh himself never completed his Cryonics Suspension Agreement with CI. Hugh could have had serious problems fulfilling his desire to be cryopreserved were it not for the fact that his Will was very explicit, his nearest nextofkin was a 3rd or 4th cousin and the Executor of his estate was a trusted friend who understood Hugh's wishes.

These are exceptional circumstances the dangers of probate can be great and in general a member should make every attempt to complete the Cryonics Suspension agreement.

Hugh's Will stated, "I hope that the Institute, of which I am a member, will be able to take possession of my body and keep it in cryonic suspension, or any other state deemed superior, for as long as necessary to carry out our aims. Nonetheless, the gift is unconditional." He specifically disinherited anyone not mentioned in his will. Fortunately, he had also completed a Uniform Donor Form which the medical examiner accepted as sufficient documentation to release Hugh to CI. (Again, the Cryonics Suspension Agreement is the primary document of legal authority for CI and reliance upon a Uniform Donor Form and Will alone would be risky.) Unfortunately, because Hugh lived alone, his death was not immediately discovered. As a result, the circumstances of his freezing were far from what a cryonicist would want.

I am personally touched not only by Hugh's devotion to cryonics a devotion I share but by the conditions under which he died. I have long been worried about elderly cryonicists who live alone and long been frustrated by my inability to come up with anything better than frequent checkup calls.

After the September, 2002 annual CI meeting I remember expressing my concern to Robert Ettinger about the danger of him living alone and the possibility that he could die in his sleep. Hugh Hart was the only other person in the room with us and I think we were all aware that Hugh was also a concern.

Projects, projects, projects there is so much to be done in cryonics and such limited resources. But I intend to do a thorough study of equipment available for monitoring and/or alerting others of serious medical and other problems. I will report on MY findings in the next issue of THE IMMORTALIST.

Joe Kowalsky shared a few thoughts about Hugh:

I think it important to mention that he spent a long time talking at the annual meetings about some people who had died that most of us did not know, because he felt it was important that we DID get to know them, and that at that point they could not speak for themselves.

Most of us just wanted to get back down to business, but I think that he was trying to keep things in perspective: we must take the time to care about people or we have lost sight of an important goal.

There are other things which I am sure will come out the importance of CI to him and his attempts to develop methods to get others involved (for CI's benefit and for their own benefit) but it is his kind consideration that struck me the most.

Robert Ettinger had these rememberences:

Although I met Hugh Hart several times in recent years, I have only a dim recollection of our first meeting, maybe 20 years ago. At that time, Hugh was a friend of Pat Dewey, sometime coeditor of The Immortalist.

We had some interesting conversations about cryonics and about trading commodities. Hugh was intelligent, and he combined qualities of prudence and risktaking, which seems typical of a considerable number of cryonicists. Also, although comfortable in company, he was a bit of a loner, which is not unusual either. Now I have recently spoken with Arthur "Buzz" Alpert, Hugh's longtime friend, and asked what he remembered about Hugh that might interest readers.

His main thrust was that everyone who knew Hugh held him in high regard as a decent, caring human being. (I see that word "caring" too much, but that's what Buzz said repeatedly, and it conveys something.) He was just a good guy.

For recreation he raised roses and collected things. Although a bachelor, he was an accomplished dancer and won many prizes as a professional dancer.

Who would have thought that!

Well, he "died" a few centuries too soon at least, but we have not given up on him.

And From York Porter:

I first met Hugh Hart, like I've met most other of the cryonicists I know, through the annual Cryonics Institute and Immortalist Society meetings in Detroit. Though it may be hard for some of my friends to believe, I tend to be somewhat shy when I first meet people and, regrettably, I have a terrible time remembering names so the initial meeting between Hugh and I was very brief and perfunctory.

Down through the years, however, as I listened to Hugh's impassioned statements on behalf of cryonics, his lament over a friend who had been involved in cryonics but who had not been suspended, and Hugh's personal plans to help the movement, both personally and financially, I became more impressed with this conservatively dressed and appearing man.

Then came an annual meeting when I accidentally insulted him and there was a period of a year or so when relations between us were not as warm. The cause to which we are all dedicated, however, intervened and after an apology by me and a gradual and gracious acceptance by him, we were "back on track" and I looked forward to seeing him at the annual meetings as well as exchanging some messages with him through both email and, since, as Hugh said, he was not much of a typist, through the regular and traditional channel of the U.S. Postal Service.

The last time I saw him was at an annual meeting and at a dinner which Robert Ettinger hosted for several of us at a Detroit area restaurant. Hugh, by happenstance, sat immediately to my right, and, before long, we were engaged in a wonderful conversation with both each other and the other cryonicists at our table.

On that night, it was revealed to us that Hugh, after his retirement which was planned for the following year, was going to work on a very personal basis for cryonics by literally going door to door to, as he put it, "save as many lives as possible". I was very, very pleased for, like Hugh, I think that the selling of cryonics is very much a "one on one" matter and I was deeply interested in his plans and approach and was looking forward to the results of this method of trying to increase memberships and suspensions.

Alas, it was not to be, but I am left with the memory of a man who was intelligent, dedicated, and innovative in how he wanted to help further the wonderful concept that Robert Ettinger thought up. Hugh, as many readers know, also, "put his money where his mouth was" by both making contributions to further the readership of The Immortalist and by leaving his entire estate to the Cryonics Institute which has resulted in a bequest of around two hundred thousand dollars. Hugh's comments, his bequest and donations, as well as his impassioned statements at annual meetings should serve to rededicate all of us to the work that lies before us.

To Hugh, all I can say at this point is a heartfelt and deep "Thank you!" and "Safe passage, my friend!" realizing that he and his future are in the excellent hands of the Cryonics Institute.


QUICKIES

People will accept your ideas much more readily if you tell them Benjamin Franklin said it first

David Comins

In the last issue we reported how the funeral industry is adapting to the number of obese cases they're getting. Now resorts are getting on the bandwagon. "Size friendly" is the description of one Mexico resort that features extra large chairs, wide doorways and wide pool steps. Happy guests can take home the resorts motto, "Live Large, Live Free" emblazoned on T shirts available in sizes up to 5XL.

USA WEEKEND

Ablocor heart implanted in 12th patient, the operation took place at St Luke's Episcopal Hospital in Houston, Texas, which has now implanted five of the devicess. The manufacturer hopes to get FDA approval later this year to sell them to the public FLORIDA TODAY

Worst pills Best pills Ever want to know what are the best and worst pills to take? Now you can get information on "DO NOT USE" drugs, and adverse drug reactions, the latest drug news, and warnings on medications: www.worstpills.org

Public Citizen

We're Living Too Long! Once Wall Street darlings as they bought up scores of independent funeral homes, the funeral home conglomerates acquisition sprees have turned into debt ridden disasters. One analyst said, "they bought too many properties at unrealistic prices. Consumers are no longer willing to be led around by their pocketbooks and be charged outrageous prices. They're also looking more and more at cremation and lower cost services. And to top it off, we're living longer! FLORIDA TODAY

When is a nut not a nut? When it's a peanut, a coconut, a lychee or a water chestnut. The peanut is a legume. The coconut and lychee are fruit, and the water chestnut is a tuber. FLORIDA TODAY


LIFE EXTENSION NEWS

Were You Deferred for "Low Iron"?

About 32% of blood donor rejections are due to a low hematocrit, better known as low iron. Hematocrit is the measure of red cells in the plasma. The red cells are the component in blood that carries oxygen to the various organs of the body. The normal hematocrit range for adults is 35 to 55.

Another way to measure the oxygen in blood is to measure the hemoglobin. (expressed as grams of hemoglobin per deciliter of blood) The normal hemoglobin range for adults is 12 to 18.5 grams. This may be the way your doctor would measure the oxygen carrying ability of your blood. This accounts for the different numbers you might hear from our staff and your doctor's office.

When a person donates a unit of blood (little less than a pint) it can lower the hematocrit by two to four points. For this reason, blood centers set limits on the amount of hematocrit a donor must have in order to make certain the donor is kept safe. These limits are determined by the FDA. The hematocrit limits for donating blood are 38 to 55. The upper limit can alert blood center staff to a possible problem in the donors blood.

If a donor tests enough under or over the limits, the staff will instruct the donor to seek medical attention. If a blood center staff member says a person's hematocrit is too low to donate today, this simply means that at this particular time, the donor does not have enough red cells to give up a unit of blood and still feel well.

This condition is often referred to as anemia. This is a TEMPORARY deferral for a temporary condition, and the person could be able to donate in just a day or two. Hematocrit levels can fluctuate on a daily or weekly basis. According to Dr. Allen Nissenson, Professor of Medicine at the University of California at Los Angeles, Inadequate nutrition is the most common cause of anemia.

Diet is an important factor in building hematocrit levels (iron). Red meat, poultry, fish, beans, green leafy vegetables, egg yolks, raisins, and cream of wheat are all high in iron. In addition, foods rich in vitamins B & C help the body to absorb iron. In some cases, just a few days of eating high iron foods can make a huge difference in hematocrit levels, as well as the way a person feels.

It is important to remember that when a donor is deferred, it is for the safety of the donor or the safety of the patient. Central Illinois Community Blood Center (Blood donations are an excellent way to monitor ones cholesterol levels, blood pressure and iron levels)

Acetaminophen Misuse can be Fatal

The government has issued a warning about the consequences of not following directions in taking over the counter medications like Tylenol, or any of over 600 other medications that contain acetaminophen. Misuse can lead to severe side effects, or even death.

More thn 56,000 emergency room visits a year are because of acetaminophen overdoses., and about 100 people a year die after unintentional overdose of the drug, according to Food and Drug Administration estimates.

Sometimes consumers swallow extra pills in hope of faster pain relief. Others unknowingly injest too much by taking more than one acetaminophen containing remedy.

The FDA is also targeting other painkillers such as aspirin, ibuprofen, naproxen or ketoprofen called NSAIDS or nonsteroidal antiinflammatory drugs. These side effects include stomach bleeding and liver problems.

"We want people to take these medications seriously, and understand the consequences if they don't follow directions.

FLORIDA TODAY

Study Finds Huge Variation In Vitamin E Absorption

Doug Skrecky recently posted this on Cryonet:

A new study has found that cereal fortified with vitamin E has a very high rate of absorption into the bloodstream, whereas pills taken separately with the same food have inconsistent effects, and taking the supplements alone is largely useless. The research was just published in the American Journal of Clinical Nutrition by scientists from the Linus Pauling Institute at Oregon State University.

The study points the way to more effective methods of taking this essential vitamin if people wish to supplement their diet. As an antioxidant, vitamin E is one of the most commonly taken vitamin supplements in the world and included in virtually every multivitamin pill.

The research may explain, Traber said, why many past research studies done with vitamin E have varied findings. It's quite possible, she said, that the manner in which people took vitamin E supplements and the variation in its bioavailability from person to person have yielded widely inconsistent results about the value of this nutrient in heart disease and other degenerative diseases.

It may also be time to consider routine fortification of more foods with this vitamin, Traber said.

"For good reasons, Americans are increasingly moving towards lowfat diets," Traber said. "But average lowfat diets provide only about 58 international units a day of vitamin E. The recommended dietary allowance of vitamin E is 30 I.U. and it's possible that higher amounts than that are useful for optimal health. So we have to find ways to make sure everyone is getting enough of this nutrient."

A glitch, the researchers say, is that vitamin E is an oil, and people are now being told to use oils very sparingly. It can be found in nuts, oily fish, some vegetables and oils such as safflower, olive and canola oil. The most common way that people get vitamin E is through rich desserts and cooking oils.

"If people are getting all the vitamin E they need through a healthy, balanced diet, that's great," Traber said. "But we really don't want to be telling people to eat more fat, and that's generally where vitamin E is found. That's why it's appealing to find an effective way of obtaining this nutrient, such as vitamin E fortification of what is essentially a lowfat food."

This controlled study was done by LPI scientists, funded by and in collaboration with the Bell Nutrition Institute of General Mills.

In it, scientists tested the results of four different types of breakfasts: a pill of 400 I.U. of vitamin E with skim milk; a serving of a wheat breakfast cereal fortified with 30 I.U. of vitamin E; a serving

of wheat breakfast cereal fortified with 400 I.U. of vitamin E; and a serving of wheat breakfast cereal with a pill of 400 I.U. vitamin E taken separately.

The pill of 400 I.U. vitamin E taken with just a glass of milk, in theory should have provided more than 13 times the RDA of this nutrient. But, in fact, it raised the level of new vitamin E in the blood by only 3 percent. By comparison, the cereal fortified with 30 I.U. vitamin E raised the blood plasma level of new vitamin E five times higher than that, and the cereal fortified with 400 I.U. raised the new blood plasma level 30 times higher.

The effect of a pill of 400 I.U. taken with a serving of plain wheat cereal was inconsistent; some participants had a significant increase in blood plasma levels of vitamin E, others almost none.

"This study clearly showed that applying vitamin E onto a grain cereal provided a huge and consistent increase in its bioavailability," said Scott Leonard, an LPI research assistant who conducted the study. "Even 30 I.U., the RDA for this vitamin, produced a large increase in new blood plasma levels."

According to Traber and Leonard, this indicates that people who are taking vitamin E supplements only with liquids on an empty stomach are accomplishing nothing and getting few if any benefits from the supplements. The vitamin clearly is absorbed better if it is part of, or closely associated with the digestion of a food that has some fat in it.

Vitamin E has been explored in recent years for its potential value in prevention of heart disease, cancer, Alzheimer's disease and other health concerns. The results of this study may explain in part why the other research has often yielded inconsistent results, Traber said.

"It's now clear that vitamin E must be taken in a certain way to be effective, either in a food containing vitamin E or in a supplement properly associated with a food," Traber said. "So anyone studying vitamin E for a clinical response must now be sure they are using it in a regimen that works."

It may also be time to consider the expansion of vitamin E as a routine food additive, she said.

"In our pursuit of lowfat diets, we increasingly are taking the fat out of foods but not putting the vitamin E back," Traber said.

According to Traber and Leonard, this indicates that people who are taking vitamin E supplements only with liquids on an empty stomach are accomplishing nothing and getting few if any benefits from the supplements.

Earth's Easiest Exercise

Walking can add years to your life, and life to your years. And it couldn't be easier.

The Conditioner Walking conditions your heart and lungs, and raises your body's ability to use oxygen more efficiently. In one study, women who walked briskly (34 miles per hour) at least three hours a week, cut their risk of heart attack and stroke by more than half.

The Protector Walking helps beat other health problems, too. I t reduces your risk of cancer and some forms of osteoporosis. It fights the battle of the bulge, taking off fat and building muscle. Walking can even help people with diabetes, reduce or eliminate their need for medication.

The Joint Saver Walking can burn as many calories per mile as jogging does. But it delivers only about a quarter of the jolt, so it's much easier on your joints and muscles.

The DeStressor Walking's easy on your mind, too, since it lessens stress and lightens depression. Beginning walkers usually report that they feel better, sleep better and that their mental outlook improves.

The Winner Best of all, walking has the lowest dropout rate of any form of exercise. So you're more likely to stick with it and get all these benefits and more, like better digestion, improved regularity and lower blood pressure.

There's Nothing To It! Just put on a sturdy, comfortable pair of shoes and go. Walk to the store for the paper,park a few blocks from work, or get of the train or bus one stop early and walk from there. Use stairs instead of elevators and escalators. On bad weather days, walk in a mall or on a treadmill.

How fast should you go? That's easy, just use the "talk test." Move at a steady clip that makes your heart beat faster and causes you to breathe more deeplybut doesn't leave you too breathless to carry on a conversation.


Hodder & Stoughton Press Release

FINAL DEPARTURES

Barry Albin Dyer, the man who lifted the lid on the greatest taboo of all death is back.

Britain's most remarkable undertaker takes an extraordinary journey around the world and across time to explore the mystery of death. Along the way he examines how different cultures and individuals mark the end of a life rituals that range from the conventional and unusual to the downright strange!

The book follows the runaway success of Barry's first book, Don't Drop The Coffin, which revealed the secrets of the funeral profession and Barry's own memories of life in London family firm F A Albin & Sons, as well as the television series of the same name which was recently broadcast on ITVI to great acclaim.

In Final Departures, Barry leaves the boundaries of his beloved Bermondsey to take a whistlestop tour of death around the world from the mummies of ancient Egypt to the technofunerals of modernday Korea and the futuristic plan to send ashes into space.

The book reveals littleknown details about the famous deaths that have affected millions, such as Elvis, Diana Princess of Wales, and Eva Peron. It also considers less wellknown but equally unique 'departures' such as the woman whose body is stored in a glass coffee table in her husband's living room!

Funeral practices range from gruesome and bizarre to beautiful and moving bone cleaning in Sicily, the 'Death Farm' in Tennessee and the Day of the Dead celebrations in Mexico are just some of the examples Barry explores. Final Departures also looks at Barry's role in repatriating the remains of British victims of the September 11th attacks in America, and remarkable stories such as the canonization of Saint Bernadette.

Says Barry: "Death is a wonderful mystery that affects every single one of us, yet we talk little about what it means to die. I feel privileged to have had an insight into cultures around the globe and wanted to record the knowledge and wisdom I've picked up on my travels and encounters in the strange, stigmatized world of funerals, death and bereavement."

Final Departures was published on 23 October 2003 by Hodder & Stoughton, priced E9.99 (ISBN 0 340 86163 0).

please contact Sarah Dennis for further information

T. 020 7873 6044 F. 020 7873 6069 sarah.dennis@... 338 Euston Road London NWI 3BH www.madaboutbooks.com

While there is no mention of cryonics in this press release, (perhaps it's no longer considered that weird) there is a chapter on cryonics. (20 pages) . There's a photo of Andy Zawacki standing next to a cryostat. Albin continues to be honest about his opinion of cryonics; that it won't work, but he is committed to complying with a person's wishes, in a professional manner, regardless of his personal feelings. He mentions the Ted Williams affair, and gives a comprehensive report on Remy Martinot, the Frenchman who had (or has) his parents stored in a freezer in his basement.


CI Member Policies to Remember

The cryonic suspension fee minimum of $28,000 (Option One) or $35,000 (Option Two) pays for the perfusion, cooldown and storage of a patient in the Detroit, Michigan area. The $28,000 or $35,000 does not include the services of a funeral director outside of the Detroit area nor for shipping costs to Detroit. A person living in California, for example, should allocate up to $5,000 in additional funding (bringing the sum to $33,000 Option One, $40,000 Option Two) . This is for Section 2 (ie. PAYMENT) of the Cryonic Suspension Agreement, if they wish to make these payments through insurance. Otherwise, funeral service costs & shipping must be paid for by relatives or friends of the Patient unless they have been prepaid and prearranged by the Patient to the funeral director.

The Local Help Rider is an agreement for CI to use money above the minimum (above $28,000 or $35,000) to pay for shipping and preparation by a remote funeral director. Minimum funding is risky and illadvised. Funding well above the minimum also allows Members to pay for more expensive cryopreservation technologies should these become available in the future or should cryopreservation prices increase for some reason.

Rider A of the Cryonic Suspension Agreement specifies what is to be done with the Suspension Fee money if cryopreservation cannot be accomplished (as, for example, would happen if a person died in the World Trade Center on 9/11 and no human remains were found). Version 1 returns the money to the estate, whereas Version 2 gives the money to CI. Version 1 may benefit relatives, whereas Version 2 benefits CI and the cause of cryonics. Version 2 (leaving the money to CI, whatever happens) may also prevent relatives from trying to block a cryopreservation for their own benefit.

Members are required to send CI verification of insurance or other funding at least once per year. CI will act immediately to cryopreserve a Member whose funding has been verified within the past year. Members experiencing a cryonics emergency on a weekend who have not verified funding within the past year may have to wait for funding verification before receiving cryonics services thus risking being straightfrozen rather than perfused. The yearly verification process can be avoided by making CI the owner of the insurance policy. CI will return ownership to any member who decides to reclaim ownership.


Cryonics Mission to Mars

By Jim Yount

Why not send a frozen guy to Mars? The British have just landed, kind of. The American Rover's shutterbug gallery is postcard perfect (see: www.NASA.gov). So when are we going to send a person? And when we do send a person, why not a frozen guy?

We could freeze him here, put him on a rocket, thaw him at the other end, and put him to work. Then when his work is done, freeze him again. Don't bother to bring him back. He will be frozen. He will have no appointments! Just keep him on ice until there are plenty more people on Mars, and they can thaw him. By then he probably won't have to work. He will be a celebrity, do Martian talk shows, and judge talent on Martian Idol. A cool gig for a cool cat.

Don't we wish? But we aren't quite there yet. We can't freeze a whole human, or any animal with a backbone, for any significant period of time; with recovery, that is. Or can we?

A Great Big Jar of Frozen "Little People"

One of the thorniest problems with colonizing Mars is the huge cost to transport people. How better to transport them than as tiny "frozen guys"? We freeze fertilized human eggs (blastocysts, also called early stage embryos). We keep them frozen for as long as is needed. Ship a couple hundred, or even several thousand, to Mars in cryogenic dewars, then bring them to term by incubating them invitro, or even implanting them in human mothers.

Teeny Boppers Take Flight

With humans acting as incubators, there would be no reason to have any men as the first colonists. The crew and colonists of the expedition would consist entirely of prepubescent girls: just big enough, smart enough, and old enough to be mentally and physically capable of establishing a permanent settlement. By "manning" our space flight with teenyboppers, we keep down the weight of astronauts, and minimize the perperson nutriment requirements inflight.

The weight of the astronaut, and the expected food and water consumption, is a prime consideration in keeping the overall payload within mission "specs." A review of the growth and mental maturity curve for girls indicates that girls of age eight would make ideal astrokids. Assuming inflight time of 260 days (consistent with minimum transit time estimates) the tykes would go though an entire school year making the trip. Their teachers would be video and computer programs, and live Earth teaches in radio contact with the crew.

According to the U.S. CDC National Center for Health Statistics pediatric growth chart, an "average" (50 percentile) girl of age eight weighs in at a trim 55 pounds, and can be expected to put on only about five pounds growth weight in the 260 days it takes to fly from lowearth orbit to a landing on Mars. Even that weight gain can be curtailed by control of human growth hormone. They could be deprived of growth hormone during the trip, and then given booster shots to allow their growth to catch up on arrival at Mars when weight is no longer such a prime consideration.

Upon arrival on the Red Planet, the young (nine years old) crew can have as many as six and a half years of work (aided, of course, by our best robotic workers) to establish living quarters before they reach childbearing age. Although adolescence can bear children as young as age 13, delaying the deliver of the first children to be born on Mars until the expectant mothers are at least 15 ½ is probably in order. The only "doctors" on the expedition, will be kiddoctors trained by computer and video programs, so there is every reason to keep the risk of childbirth as low as possible.

How many astrokids/colonists would be needed for our girlpower crew? Because most of the future colonists are being transported as fertilized eggs, we need not be concerned that the small number of astrokids will result in low "genetic variation." In his 1971 "Jenken's Report," Morris Jenkens called for five mission specialists in his suggested "there and back" scenario. His specialists included: Mission Commander, Systems Engineer, Geologist, Physician, and Geochemist. The crew of the oneway only "children's crusade" could certainly number at least twice that count of diminutive passengers. The experience of Jenken's crew would be more than made up for (in some situations at least) by "expert systems" in the computer, and the expected long years to gain experience by the youthful spacers.

Each mother could bring to term six to eight frozen tots in her lifetime. In theory, the young women could do twice that, but that would be to turn them into nothing but walking baby factories rather than colonists and explorers with big families.

The second generation of Martians (the first generation born on Mars) would be ready to procreate about 16 years from birth. From a standpoint of buildingup the colony, there is no reason for more than a couple of males born every generation, and those purely as "backups" should there be a failure in the frozen people program. However, from a sociological standpoint, the number of males would probably be increased above this minimum. I would be content to leave such decisions to the Martians; they are the ones who will have to live with such choices.

Given that six out of eight Martians born in the first four generation after planetfall would be female, and that the colony is able to expand living space and other resources apace with population increase, the buildup would look like this:

Martian Population Increase

Female Male Generation Total Overall Total At Year

Planetfall generation: 10 0 10 10 0

2nd generation 60 20 80 90 1635

3rd generation 360 40 400 490 3251

4th generation 2,160 720 2880 3370 4867

As you can see from the chart, starting with just ten preteen female colonists, the Martian population would be two to three thousand after just sixty earth years.

The years are "earth years"; zero death rate is assumed. When death finally does start to claim nativeborn Martians, the prospect of cryonic suspension may be especially appealing to them. They will, no doubt, remember that a good many of them arrived on planet as "frozen guys".

This scenario is not attractive to teenage boys of our generation hankering to be space cadets or Martians. But all those unmated females on Mars might be an added attraction for future male tourists on Martian vacation!

There is another interesting scenario where all births are invitro, and there is no need for females as baby incubators. Under those circumstances, the numbers of female vs. males given in the chart above could be completely reversed.

It must be emphasized, however, that having a population of Martians as the originally colony, and later to largely be made up of teenage and preteen boys is definitely NOT a good idea. Once they tamed Mars, they would, likely as not, return to the earth to try to take over a second planet!

Frozen Guys of Mars

By having our women found Mars, there is no need to waste valuable fuel and payload on a return trip. Another way a oneway trip could be achieved is as a variation of the old "suicide mission" scenario. We would recruit, as Mars missioners, people who wished to be frozen when they died and who had some terminal medical condition, which made death likely within a few years.

With the ambient temperature on the red planet averaging about minus 53 degrees Celsius, a death anywhere on Mars would assure one of being frozen. That temperature is low enough to provide a pretty good "freezedry," but not nearly as cold as a cryonicist would hope for. Still, there are some of us who think that even temperatures of a Martian hotspell might be good enough for adequate preservation of enough information describing "the person" to be worthwhile. If the spacecraft and exploration crew consists of several terminal ill cryonicists, then it may well be possible to set up selfservicing "cold chambers" on Mars that use wind or solar power to run generators to liquefy gas from the atmosphere, which would then act as a media for keeping the astronaut/cryonaut cold. Two point seven percent of the Martian atmosphere consists of Nitrogen gas, just waiting to be liquefied for us cryonicists!

Under this scenario, given a crew of two or more, there would (of course) be a "last man standing" who would either have to freeze himself, or depend on the ambient Martian temperature to keep him cold.

The future revival of these cryonaut missioners would be dependent upon 1) the eventual permanent colonization of Mars; 2) the attainment of a level of technical sophistication on Mars commensurate with cryonics revival; 3) the attainment of some technology, somewhere, capable of reanimating the subjects; 4) the will of people of the future to undertake the reanimation. On this last point, there is good reason to believe it will come about. The cryonicist who dies and is frozen under such circumstances will likely be regarded as a hero to future Martians.

Choosing cryonicists for this mission would not be easy. The medical condition would have to be such that it is highly likely that the person will not live an extended time, but such that the medical condition would not interfere with doing active work for the expected duration of the mission, perhaps several years.

Use of the services of the terminally ill cryonicists on a oneway trip to Mars would be a fairly quick way to achieve a permanent Martian settlement. Such cryonicists could establish rocket fuel processing centers, for example, to make routine EarthMars round trips practical. The Martian atmosphere could be "mined" to produce hydrogen, hydrocarbons, or argon gas as propellants for earthbound (return trip) spacecraft. Other chemicals, taken from the atmosphere or from Martian soil, can produce other useful chemicals, such as ammonia for growing vegetables in the colony greenhouse. Interestingly, liquid nitrogen is a byproduct of a number of those chemical processes! Permanent settlers or twoway trippers would find a working habitat in place when they arrived, along with some frozen cryonauts! And all thanks to the Frozen Guys of Mars!

Reality Check

Space exploration has proved to be dangerous work. There is no reason to believe that tripping to Mars, and establishment of colonies there, will be any less hazardous. Neither of the proposals made here, are apt to be adopted, at least not by the US. NASA seems always in a publicity campaign to justify itself and its programs as somehow benefiting us in the short term, rather than simply because we need to do science! The idea of sending little girls with frozen human eggs on a oneway trip to Mars is not apt to become a NASA proposal! Neither is the plan to recruit cryonicists with terminal medical conditions to do a "suicide" mission.

When we finally do send men and women to Mars, and later attempt colonization, the loss in lives, squandering of resources, and waste of time may prove far more foolish and costly than implementing either of these "radical" proposals.


Death and Cryonics: A Case for Immortality

by Sara Olson

Sara is currently living with her fiancée while studying English at Newman University in Wichita, Kansas. She's originally from Minneapolis, Minnesota and the couple plan to return there after she completes her education. She has an extensive interest in anthropology, the arts and literature, and looks forward to "studying them even more extensively in the centuries to come." She recently signed a suspension contract with CI, after getting a life insurance policy through Rudi Hoffman.

At the age of seven, I was given the best argument for life extension and immortality that I could ever experience. My grandfather died the January after my seventh birthday, and though I remember very little about the entire ordeal, I still very vividly remember one short moment from that mortifying weekend.

The surroundings are blurred out in my memory, as if the camera of my mind's eye carried a heavy diffusion of all but the most important people present with me that day. And of course my mind recalls with acute clarity the most important person of all present, but simultaneously not present, in that room: My grandfather. My Uncle Terry picked me up, his eyes filled with tears (I believe that he was the first man I had ever seen cry). We both stared, disbelieving, into the coffin, gazing for the last time upon the empty death pallor of my grandfather.

"You can touch him if you want to," My uncle offered. I had never touched the dead body of any creature before, let alone a human. I was curious and frightened by the idea, but overcame my momentary revulsion enough to reach out and touch death with the innocent curiosity of a child.

It is easily the worst thing my hands have perceived. The flesh didn't feel human. Devoid of any heat or even the ghost of life, this was truly death incarnate. Even the chair I had been sitting in while waiting for the viewing to start seemed to hold within it more life than this frightfully frigid husk of flesh and bone that lay before me. At least the antique piece of furniture I had previously occupied felt as if it resonated with a piece of those who had occupied it in the days and decades before me. But when I touched his fragile shell, there was nothing. Nothing was left there of the man I had loved and played with for the first seven years of my life.

Fifteen years later, all I have to do to rekindle my desire for a life without death is take myself back to that warmly formal room, stand again in front of that repulsive metal box, and reach out and once again touch the antithesis to life that lay before me that snowy January evening. I know that if it comes to it, I will not abide even the idea that I could spend eternity in a coffin slowly decomposing into dust, or, even worse, transforming to dust in a matter of hours in a mortifyingly violent kiln. Neither of them offer me even the faintest hope of ever emerging from that terrible state that I experienced that day.

When I learned about cryonics, I knew I had found my lifeboat. If, heaven forbid, it comes to the point where this body fails me before medical technology allows me to extend my life, I knew that cryonics would buy me the time I need to get my body to the time when my survival will be able to be guaranteed.

Though cryonics may not be the ultimate answer, it gives hope that my grandfather no longer has. Cryonics offers me the opportunity to someday emerge, victorious, over that abhorrent state of notbeing that I experienced through my grandfather so early in life. My grandfather's last lesson to me was, by far, the longest lasting and most important. Life is a gift to be held and treasured as often as possible. The alternative is inconceivable and irrevocable.

For me, there is no alternative.


Cold Water Drownings

Recently, someone questioned on Cryonet, the relevance of cold water drownings to cryonics. Charles Platt replied:

Coldwaterdrowning cases who have been revived after an hour or more without vital signs are relevant to cryonics in several ways.

1. They are living proof that postmortem brain damage can be delayed by hypothermia, especially if cooling occurs initially while the heart is still beating.

This is an important factor because blood circulation can withdraw heat from the body and brain far more rapidly than surface cooling alone, after the circulation has stopped. This should be reassuring to members of any cryonics organization that cools the patient promptly after legal death has been pronounced, provided an ice bath is supplemented with cardiopulmonary support to sustain some circulation of the blood.

2. They demonstrate that cellular processes in the brain can restart spontaneously after a period of total dormancy. Consciousness returns and memories are preserved. By extension, cryopatients may be similarly revived after decades rather than hours of stasis. This is a major credibility issue for many people.

3. Resuscitation of patients after more than an hour without vital signs is a direct challenge to anyone who believes that the soul leaves the body after "death" occurs. Since revived patients do not behave like zombies, we have to assume that the soul, if it exists, is still present. Therefore, either the soul doesn't leave, or there is no soul, or the person wasn't really dead. If the drowning victim wasn't really dead, then cryopatients aren't really dead either (so long as they have been properly cryopreserved).

I have debated the relevance of coldwaterdrowning cases at some length with a friend who feels that the cases are less convincing than, say, the catbrain experiments performed by Suda. Usually the coldwaterdrowning cases do not provide specific data, such as the exact time when cardiac arrest occurred. Nor was anyone able to measure brain activity or body temperature. Thus the cases are dissatisfying compared with properly controlled lab work.

On the other hand, when trying to present cryonics in a way that people find palatable, I prefer to avoid the disturbing image of isolated cat brains being reperfused with blood. I think it is much easier to talk about cute little children who are revived after being very very cold.

Most journalists apparently share this outlook; the case of Brittany Eichelberger (who was rescued from a snow drift one Christmas Eve) was featured twice in People magazine, and she also appeared on TV. Thus far, the isolated cat brains have not attracted an equal amount of media attentionand if they did, I doubt it would be as positive.

Numerous cases of coldwaterdrowning, followed by resuscitation, are reported each year. You'll find a bunch of histories (some on PubMed) if you use a search string such as "cold water drowning" resuscitation

Charles Platt


Two Davids

David Devor writes

I read, with interest, in a recent issue of The Immortalist, David Pizer's recommendation to speculate in real estate in your area based on rumors of a Six Flags venture.

David Pizer replies:

I hate to call it a recommendation.

Should the Cryonics Institute decide on such land speculation and accept foreign participants, I would be interested in buying a piece of the action. BTW, I'll be visiting Miami on Dec. 1524 for a conference there.

I doubt if it would be considered safe enough for a cryonics company investment. But gamblers might want to take a small chance here. Especially if you were using money you could afford to lose.

Editor's note: David, (Devor) I'm just the editor here, but based on past experience CI does not want to get into other ventures. Its only purpose in life is to freeze and store those frozen. The only departure so far has been to accept tissue samples for freezing from members. Why don't you write to Pizer himself?? (Pizer is located in Arizona,, I'm in Florida..)

Sorry to bother you again, but have you an email address for him? I was thinking that if you published my letter, it might get some echoes. If the entry cost is low enough and the upside very great, even Prof. Ettinger might think it worth doing in some kind of framework if not the C.I. itself. It does sound like a rare opportunity.

I am not sure this is a good investment for a group of people who don't know each other. I am not an expert at putting groups together. There is some risk here.

David Pizer


Long Term Personal Storage at CI

Recently there was an inquiry about CI providing members personal storage space. This discussion took place at Cryonics_Institute@yahoogroups.com

From Ben Best

The figure I quoted of $6 per year for a banker's box volume in a limestone cave was secondhand information from what I believe is a reliable source. But people who are interested should take prices directly from the vendor, and not from me.

I have previously felt that our storage allowance were too generous and now as President (with Robert Ettinger's agreement) I am implementing a new policy for perpetual storage. A Member will have a 2inch limit on the amount of material they can include in their Member/Patient file for perpetual storage. Members/Patients who currently have more than this amount will be grandfatheredin at their current holdings.The two inches includes all of the signup documents, insurance and similar materials, plus whatever else a Member may want to send. Option Two Members can have two inches as well, but if they do not keep their dues paid, they lose the privilege, unless they become patients.

Members who want more space can buy space in a lockable filing cabinet drawer which will be reserved for them in perpetuity. The filing cabinet will be on the CI premises and will be protected with nearly the same diligence as the patients. The drawer volume is 2feet deep, 1foot wide and 9inches high. The cost will be $1,000 per drawer. Although filing cabinets are not expensive, perpetual storage space has a cost. Option One Members can buy the space predeanimation, but Option Two Members can only buy the space as patients. Option One Members can remove materials and add materials from theirdrawer(s) at any time, but must pay shipping and handling costs.

Perpetuity means forever. We will have an agreement similar to the suspension agreement.

Realistically nothing is forever the Sun will burnout, entropy will rundown, and protons will decay. But try taking us to court after protons have decayed! Seriously, CI will make "best efforts" to maintain these drawers in perpetuity for as long as they are wanted.

Ben Best

Again, from Ben:

"Carl" writes:

$1000 for a file drawer? Is it made of solid gold with platinum handles?

Carl

The filing cabinet is not expensive. Preservation in perpetuity requires both real estate and stewardship. Compare this with storage prices at other sites eg http://www.publicstorage.com/ where you will be paying lots more for a few decades of storage.

Shoparound and let me know if you can beat this price anywhere for even 100 years of storage for a comparable volume. I doubt that anywhere else even offers perpetual storage. Mind you, perpetual storage does mean "until something goes horribly wrong", like a nuclear strike. But in that case, the patients and our own lives would be lost as well.

Ben

"Giuseppe" wrote:

Please, I like to know if CI can store just one CD of personal data in the suspension member's file indefinitely (free of charge). It would include an autobiography, major event photos and a character/personality profile. I think that this would be enough for me to reconstruct my memory. What does everybody think about this?

As I mentioned, every CI Member can use up to 2inches of file folder space at no extra charge. With the normal amount of paperwork, a single CD should add about 3/8 of an inch (just under a centimeter) to your width allotment and therefore be within bounds.

Ben Best

From:"ladyrhianna"

As to the storage issue, I personally wouldn't expect CI to hold anything serious, if anything at all. Maybe a space the size of a couple shoeboxes for each member for the items they know they'd want immediately upon revival (some jewelry, a book or two, personal papers, etc). This is all I would personally and reasonably expect from CI in this regard. What you would choose to charge for such a service is, of course, completely up to you. I'd say whatever you need to charge in order to cover those costs.

My thought would also be that, if a person chooses storage of some possessions offsite, it would be nice if CI could keep records of what is stored where, in case one's memory did not make it through suspension completely intact, so they could at least reacquire their personal items (Even if, god forbid, they didn't quite remember what they were or why they were significant .

From: James Swayze

Forgive me if I am mistaken and perhaps conflating Alcor policies with CI's but I thought we already stored a certain size of container for each member. I agree, however, that the benign atmosphere of the limestone mine facility would be better for certain types of data. One should try where possible to scan all photos and documents into digital form because certain paper medium can deteriorate with time, especially acid treated. Photos can fade depending how old they are to begin with. Digitizing also decreases the size but where one might want the originals to survive for sentimental reasons a backup is wise and moreover a duplicate backup at a different local is wiser.

If one is thinking about storing collectibles for sentimental reasons this is fine but if expecting them the be an investment it is my opinion that future technologies will allow the complete, down to every minute scratch at the atomic level, duplication therefore rendering all collectibles for investment valueless. The only items of this nature that will be safe will be those encased in acrylic and under 24 hour guard from anyone slipping a few nano spies onto so to record the duplication map. In other words, in my humble opinion, don't waste your time and money trying to horde gold coins or whatever.

These subjects are vital to our endeavors and especially discussions about how we might actually achieve reanimation. Now is the time to plan our revival and what terms for it we would accept. As someone pointed out having a more complete map for the journey goes farther for gaining new members than does proselytizing them with our faith that others will do it for us when.

As to reconstructing memories and let's not forget also *personalities* that might not weather the trip so well I think it is useful to record what types of media or meme generators that influenced you to become who you are and why you made this and other choices. To this end, as it has been discussed on cryonet before, we each need to make a video interview to ourselves to be played back upon need after reanimation. Perhaps the conversion of such from tape and other media to DVD could be something it would make more sense for one agency such as CI to handle rather than we each trying so on our own.

Questions:

1. Why only one hundred years storage at the Underground Vault Storage facility?

2. Could they be persuaded to extend it?

3. Does anyone have the price for prepaying that one hundred years worth of storage, $6 one time fee sounds too good to be true to me?

James

From John de Rivaz

You need to be aware that data on CDs will only last of the order of 50 years. Also CD standards and players last only a few years, and it would be necessary for CI to keep the digital files re recorded into the latest format as standards change. Maybe a permanent nanotechnology based standard will emerge, but the history of technology suggests that standards never last long. Try replaying an old wire recording, for example, or even a video tape recording made with an early Sony domestic VCR, such as the CV2100CE.

John de Rivaz:

From RonHavelock

John, all of what you say is true about standards. (I have a lot of old beta tapes and a beta player somewhere in the attic to demonstrate the point) but we are also getting better and better at retrieving old stuff. I doubt that retrieving material from an old wire recording would be much of a challenge to an expert in such things any more than reading heiroglyphs is a challenge to an Egyptologist. Classicists like my late father have been reading Greek off pottery chards for generations. That stuff goes back 3,000 years. The great advantages of digital recording are [1] extreme accuracy, [2] extreme compaction, and [3] extremely rapid and cheap transfer within and across media. These are all important for storing large quantities of material which are important in preserving aspects of our personal identity.

I am not sure where you get your "50 years" from but the third feature I mention above suggests the possibility of moreorless infinite preservation simply by transferring items to the most advanced media of the time, assuming there is somebody on hand who cares. Additionally, as we move toward nanotech, required space will shrink, not expand, so that the storage costs for any one individual will become minimal if not even miniscule.

CI might be well advised to move aggressively into the identity storage business, adding a very positive and noncontroversial feature which might even attract new cryonauts if done well. Thus a subscriber could say to his or herself, "well, even if they can't bring me back, I have preserved a record of many of the things which are most important to me. Somebody some day may open up my recorded self and, to some degree, reexperience the life I have had."

Ron Havelock

p.s. this is a potential project to which I might be willing to devote some time and effort in league with others.


Small Print:

For more information about cryonics or Cryonics Institute and how to become a member, visit our web site at http://www.cryonics.org.

We encourage readers to forward issues to friends and interested parties. Please send any suggestions or comments to Long Life by emailing John@...

Long Life would like to thank Longevity Report, Wired News, InfoBeat, The New York Times, The New Scientist, Nanodot, Slashdot, contributors to the Extropian and CryoNet mailing lists, members of the Cryonics Institute, and others, for helping provide some of the free public information used in Long Life.

(Disclaimer: CI does not necessarily encourage or advocate the use of any products or practices mentioned in its newsletter.)


--
Sincerely, John de Rivaz: 
http://John.deRivaz.com for websites including Cryonics Europe, Longevity Report, The Venturists, Porthtowan, Alec Harley Reeves - inventor, Arthur Bowker - potter, de Rivaz genealogy,  Nomad .. and more

#28 From: "John de Rivaz" <John@...>
Date: Thu Jan 15, 2004 5:06 pm
Subject: Long Life vol 3 no 1 - Immortalist Highlights
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Long Life: the Cryonics Institute newsletter

January 2004 -- Volume 3, Number 1 - Immortalist Highlights

Welcome to Long Life -- the electronic newsletter of the Cryonics Institute. We're here to update you with brief cutting-edge news, updates, links, and information about the latest scientific, medical, health, anti-ageing, and social developments relevant to CI's goal of saving, preserving, and extending human life. Long Life may also include news about Cryonics Institute events and member activities and opinion. We welcome your feedback, and encourage readers to forward issues to friends and interested parties.

There are separate issues for highlights from the latest issue of The Immortalist. The reason for this is that otherwise the file is too long for some readers, and also the publication dates of The Immortalist are not synchronous with the start of each month.
 
I would also urge readers to subscribe to the paper issue of The Immortalist (see http://www.cryonics.org/info.html ) as not everything is reproduced in this email version.
 

Note -- publication of the other issue of Long Life was suspended during the cemetary board cease and desist order. It is hoped to return to normal service soon.

From the Immortalist: 
 
EDITOR’S CORNER
MEMORIAUM
NEWS & VIEWS
Quickies
A Guide to AntiAging Drugs
Christopher Reeve’s Quest
CI ONLINE DISCUSSION GROUP
KURZWEIL NEWSLETTER
ISCHEMIA AND REPERFUSION INJURY IN CRYONICS
LIFE EXTENSION NEWS
MEET DANILA MEDVEDEV
 
EDITOR’S CORNER

This issue of The Immortalist is a milestone of sorts. It’s the first issue with a full color, full page, PAID advertisement! In case you missed it, it’s on the outside rear cover, a Life Extension Foundation (LEF) ad. The ad is the result of a conversation Ben Best had with Bill Faloon, LEF’s President, when he was in South Florida recently. Good job Ben! And as they say in the business, "support our advertisers!" The CI ad that was formerly on the rear cover has been moved to the inside front cover.

With all the food manufacturers jumping on the low carb bandwagon, it’s good to remember that just a few short years ago, anyone who even mentioned Dr, Robert Atkins and his revolutionary weight loss ideas, was branded a quack and a nutcase. He wrote his first book about the "Low Carb Lifestyle" thirty years ago. Atkins died this past April after slipping on a patch of ice in front of his Manhattan office. It’s only been recently that his ideas have been vindicated. It’s a shame he couldn’t live to see how things have changed.

One wonders if the change in the public perception of cryonics will happen just as quickly, or will it take a prolonged period.

MEMORIAUM

The Immortalist Society (IS) Research Fund. recently received a donation from Maureen Genteman. She is an IS member, the donation is in memory of her husband Paul. Paul Genteman has been suspended by Alcor.


NEWS & VIEWS

President's Report

The Cryonics Institute has reached an agreement with the Michigan Department Labor & Economic Growth (DLEG) Bureau of Commercial Services to be licensed as a cemetery. The Cease and Desist orders issued by CIS against CI have been withdrawn.

Ben Best

I did not want for an issue of THE IMMORTALIST to be published pending this important announcement, so I asked our editor/publisher (John Bull) to hold publication.

Although the issue is very late, I think it was worth waiting. The Nov/Dec issue of THE IMMORTALIST has been skipped, because I asked John to make the next issue Jan/Feb. All subscriptions will be extended accordingly.

Concerning the agreement with DLEG, CI agreed to be licensed as a cemetery without waiving its claims and objections regarding the lack of jurisdiction of DLEG or the Cemetery Commission over CI. CI's purpose is to attempt to save lives, not to store dead bodies. CIS has acknowledged the distinctive nature of cryonics.

CI can no longer perfuse patients at the CI facility. All perfusions done in the state of Michigan must be performed at the premises of a licensed funeral director -- although the protocol and perfusates are still those intended for cryopreservation, and can be modified when we are ready to implement vitrification. Because funeral directors already perform our perfusions under our direction (and will continue to do so under our agreement), we believe that we can operate and continue to improve our protocols at the premises of a funeral director.

The terms of the licensure also require the creation of an Endowment Care Trust Fund for patient care -- amounting to $4,000 per patient. (This is a bookkeeping transaction, is done internally in CI’s books, and has no effect on members at all) The interest from this fund can be used for patient maintenance and maintenance of CI's facility. The existence of a separate fund is required for all cemeteries, and is intended to provide an extra assurance that funds will be available to maintain our patients. CI will continue to hold more than this amount for patients outside of the Trust Fund in addition to the minimum requirements of DLEG.

A press release was created by negotiation and mutual consent between our lawyer (David Ettinger) and DLEG. This official press release was given to the media and is printed elsewhere in this issue of THE IMMORTALIST.

While CI has not sought out regulation, there are advantages to this result. By reaching an agreement that recognizes the many differences between CI and cemeteries, we believe that we have achieved a "benign regulation" that is intended only to provide additional protection to our members, and therefore have avoided the problems of hostile regulation.

Also, there are people who feel that their consumer's rights are being safeguarded when they deal with a regulated industry, so such people may be more comfortable about making cryonics arrangements with CI.

I regret that our members have been in the dark about this situation for so long -- wondering when or if this will be resolved, wondering what services CI can provide, and wondering how much of a problem it would be if a cryonics emergency arose.

We did have contingencies, but because of the sensitive legal situation it was better not to discuss them (and is probably still better not to discuss them). It is my preference to be open about matters when feasible and to have an open discussion of real problems with all our members as much as possible.

I look forward to not only resuming operations that are faithful to our purpose along with advancing technology & service -- but to resume efforts to establish open dialog with the membership.

Ben Best

_________________________________

News Release

Michigan Department of Labor & Economic Growth

Cryonics Institute Now Licensed as Cemetery to Settle Dispute with State of Michigan

January 7, 2003 - The Michigan Department of Labor & Economic Growth (DLEG) Bureau of Commercial Services, and Cryonics Institute (CI) have settled their dispute by the licensure of CI as a cemetery under Michigan law.

CI is a nonprofit membership organization which "cryonically suspends," or freezes, patients immediately after clinical death, in the hope that they can be revived and rejuvenated when future technology is sufficiently advanced.

DLEG had issued orders requiring that CI cease and desist from many of its activities pending licensure.

Now that CI has been licensed, these cease and desist orders have been withdrawn.

"We are pleased that CI can now become a licensed facility, permitting state oversight of its operations," said David C. Hollister, Director of the Department of Labor & Economic Growth. "We believe that it’s licensure as a cemetery provides additional protections to the people of the State of Michigan."

"CI is very happy to have resolved this dispute, so that we can continue to grow and provide services to our members," said Ben Best, CI’s president. "While we believe that CI’s activities are very different from those contemplated by the Michigan laws governing cemeteries and mortuary science, we are ready to become licensed, and to permit oversight by DLEG staff.

Our agreement with DLEG recognizes the unique nature of CI’s services, and, as a nonprofit membership organization, we have always operated in the manner that best serves our members."

The agreement between DLEG and CI in most respects permits CI to continue operating as it has in the past, but subject to audits, inspections and financial reporting. CI will also segregate certain funds in an endowed care trust fund to cover maintenance expenses.

Additionally, CI has agreed that certain initial steps of the cryonic suspension process within the State of Michigan will only occur at licensed funeral establishments, conducted by licensed morticians. Such activities have in the past been conducted by licensed morticians at CI’s facility. Patients will still be stored at CI’s facility in liquid nitrogen.

The Bureau of Commercial Services of DLEG, licenses and regulates the practices of mortuary science, funeral establishments and cemeteries in Michigan. The Cryonics Institute is a nonprofit, membership organization based in Clinton Township, Michigan. CI has cryonically suspended 50 patients, and has more than 400 members.

_________________________________

BOCA RATON PLANNING & ZONING BOARD HEARING, 6-Nov-2003

On November 6, 2003 at 6:30pm -- there was a hearing by the Planning & Zoning Board at Boca Raton (Florida) City Hall. The first item on the agenda was the application for zoning approval by Suspended Animation, Inc. Although the final decision on the zoning application is made by City Council (which meets in January), the recommendation of the P&Z Board can be a significant input in Council's decision. With P&Z Board approval, the Council would be almost certain to approve.

In the week prior to the meeting (particularly) Suspended Animation made an ardent appeal to cryonicists to attend the P&Z Board hearing. Appeals were also made to e-mail the Council membbers and the Mayor. The latter appeal may have created some confusion. The Mayor's auto-responder mentioned the Council meeting in January -- and some cryonicists who might have attended the P&Z Board meeting got the mistaken impression that it had been postponed until January.

At 6pm those attending the P&Z Board meeting were allowed to enter the City Hall Building. Everyone entering was required to show photo ID and to walk through a metal-detector. Outside, about 15 animal-rights activists stood on the

street-corner chanting to motorists and waving signs & banners. Reporters from Channel 5 (http://www.TCPalm.com) and News 12 covered the events outside as well as in the hearing.

Anyone in attendence in the courtroom willing to state their home address and be sworn-in was given the opportunity of making a 5-minute testimony following the introductory briefings. The Chairman of the P&Z Board stressed that repetition would not be welcome and further attempted to intimidate would-be testifiers by saying they would be subject to cross-examination (which never happened). He was also concerned that all of the animal rights activists would be saying the same thing, so he requested that a spokesperson be appointed to speak for the group.

The first briefing was by a P&Z staffer who described the zoning of the South Congress Industrial Center (SCIC), which is zoned as M-3. She said that mortuary use is not permitted in an M-3 zone and that Suspended Animation (SA) does not qualify for the Conditional Use petition. She then named the activities qualifying for Conditional Use, which included such things as bottling, TV repair, heliports -- and laboratory/industrial research & testing.

The SA lawyer then argued that SA is not a mortuary, but is a research organization. SA President Dave Shumaker then gave a rapid-fire presentation describing the scientific credentials of his staff & consultants as well as a scientific justification for cryonics research – stressing that any animals used would be treated humanely.

The P&Z Board Chairman interjected to ask "if cryonics works, what will we do with all the people?"-- adding a disclaimer that his own question is irrelevant to the decision. Mr. Shumaker said that Man is adaptable and that additional population could be handled, just as the world is currently sustaining 6 billion people without a problem (causing some groans among the animal rights activists).

About 10 people testified in support of SA, whereas only 4 animal rights activists testified against (and one of the 4 was a written briefing). The animal rights activists summitted to the plans of their leadership (as had been requested), whereas there was no co-ordination among the cryonicists other than to encourage as many as possible to speak. The animal rights activists were sitting together en mass in the back, but they refrained from jeering & cheering when reprimanded by the judge about doing so.

Bill Faloon testified as a licensed Florida mortician, stating his license number. He testified categorically that the practice of cryonics is completely unlike what a mortician does. One of the animal rights testimonies was an emotional appeal by a Boca Raton woman, but the other two opposition testimonies strove to cite scientific authorities who supported the claim that cryonics is crackpot pseudo-science and that SA would be conducting frivolous & unnecessary experiments which would cruelly torture animals as part of a scheme to dupe desperate people with false promises in a profit-making scam.

I surprised myself by making a mostly emotional testimony. I said that I have been interested in cryonics most of my life and that I wear a bracelet that says I am donating my body to cryonics research. I said that I do not believe immortality is possible, but that cryonics has the possibility to save & extend lives. I said that I view cryonics as medicine and that if they prohibit cryonics out of concern for overpopulation, they should also prohibit heart transplant, kidney transplant and all medical research. I noted that 21st Century Medicine had cryopreserved rabbit kidneys at -50C and successfully transplanted the kidneys into the rabbits with complete recovery.

I said that I hope that cryonics can save my life, but if it does not I hope that my donation to research may help the next person (comparable to an AIDS victim subject to an experimental treatment). I said that I have many friends who have made similar arrangements as well as friends already frozen. I said that I care about animals, but that I also care about my friends. I was becoming so emotional that I felt I should end on that note.

After the testimonies the P&Z Board basically said that the testimonies had all been irrelevant. The staffer in the initial briefing had established that a mortuary is unsuitable for M-3 zoning and that SA clearly does not qualify for the Conditional Use petition. All 6 P&Z Board members agreed unanimously to deny SA the Conditional Use petition. A roar of cheering and clapping came from the from the animal rights activists in the back of the courtroom.

The hearing was then recessed and most people left. I heard three of the P&Z Board members chatting & laughing between themselves about what great entertainment the proceedings had been.

It is possible that when Council meets in January that it will overrule the Planning & Zoning Board, and approve the Conditional Use petition that Suspended Animation has made.

Ben Best

_________________________________

ETTINGER’S MAKE RESEARCH FUND DONATION

David and Connie Ettnger have made a $20,000. donation to The Immortalist Society’s Research Fund.

_________________________________

TED WILLIAM’S SON DIAGNOSED WITH LEUKEMIA

SPORTS ILLUSTRATED reported that John Henry Williams, 35, was diagnosed with leukemia earlier this month, Eric Abel, Williams' attorney would not discuss any other aspects of Williams' condition.

John Henry Williams told the Citrus County Chronicle that he was diagnosed with acute myelogenous leukemia at UCLA Medical Center and that he has already started chemotherapy.

"The whole goal is get the leukemia in remission," Williams told the newspaper.

After Ted Williams died July 5, 2002, John Henry Williams was at the center  of a controversy surrounding his father's remains. Williams had his father's body taken to Alcor, setting off a battle with his half-sister, who said her father had wanted to be cremated.

The matter was settled in December, when Bobby Jo Ferrell, Ted Williams' oldest daughter, dropped her objections.

John Henry Williams' other sister, Claudia Williams, told the newspaper she is in Los Angeles for tests to determine if she is a match for a possible bone marrow transplant.

"It's not good, not good at all, considering his age," Claudia Williams said.

About 10,500 new cases of acute myelogenous leukemia are diagnosed each year in the United States, with remission occurring in 70-80 percent of those patients.

Ted Williams finished with a .344 career average and was the last major leaguer to bat over .400, when he hit .406 in 1941.

________________________________

CHRISTINE GASPAR’S FIRST TV INTERVIEW

Brent Erskine and I did an interview for a television production called TKO (technical knockout). It’s produced by Pyramid Productions, and I think is channeled through Global / Canwest. It airs primarily in Western Canada, but those of you with time shifting from Rogers Cable might be able to pick it up. They will nevertheless send us a copy of the show on tape. I think it went incredibly well. We spoke with the videographer for more than an hour, and it was unscripted, which was nice. (I didn't read from the notes I had prepared, and Brent spoke off the cuff too) I'd like to thank Brent for participating. I think this will be a positive presentation of cryonics to the community at large. As well, being the first time either of us have done this, it was a great learning experience. I hope that we can do more of these, on a regular basis, as I think it will go a long way towards one of our goals (at least one of mine anyways) of normalizing and legitimizing cryonics to the larger Canadian community.

Christine Gaspar

President, Cryonics Society of Canada _________________________________

INITIATION FEE COMING FOR NEW OPTION TWO MEMBERS

Starting March 1, 2003 Option Two CI membership will require a $75 initiation fee to cover set-up costs in addition to the usual $120 per year (or $30 quarterly) payments. If you have friends or relatives who have been procrastinating about joining CI as an Option Two Member, encourage them to join before the March 1st deadline to save on the cost of the initiation fee. Note that in addition to checks & PayPal,we now accept Visa, MasterCard and American Express for payments.

_________________________________

SCRIPPS RESEARCH INSTITUTE TO OPEN FLORIDA BRANCH

The Scripps Research Institute is one of the worlds largest non-profit biomedical research organizations. It’s internationally known for its research in immunology, molecular and cellular biology, and a number of related fields.

It was founded in 1961 from it’s predecessor, The Scripps Metabolic Clinic which was founded in 1924 after a gift from philanthropist Ellen Browning Scripps, who herself was an heiress of the Scripps Howard newspaper chain.

Their California facility is located in LaJolla, and employs about 3000 people. This figure includes 288 principal investigators, (3 Nobel Laureates,) 15 fellows of The American Association for the Advancement of Science and 775 postdoctorial fellows.

The physical layout consists of 12 buildings with more than a million square feet. This year Scripps received nearly $205 million in research grants from The National Institutes of Health. The area around the LaJolla campus is surrounded with buildings with names familiar to everyone, Pifzer, Merck, Johnson & Johnson, to name only a few. All arethere to maintain a close working relationship with Scripps.

Now Scripps wants to do for Florida what they did for California. Governor Bush learned this past summer about Scripps desire to open a facility on the east coast.

With stunning speed , and a level of security not seen since Disney came to Orlando in the 60’s, Bush courted Scripps with enthusiasm and intensity. He christened the secret venture, "Project Air Conditioning," likening it to the radical changes to Florida with the advent of air conditioning.

Subject to approval by the legislature, Florida is offering $310 million to pay for technology and salaries for Scripps Florida employees for several years. Palm Beach County, where the facility would be located, has offered up to $200 million for land, a new building and temporary headquarters.

Scripps claims it would be a magnet for other research organizations and laboratories that would attract leading academics and professionals. Scripps President Richard Lerner has said the Florida facility would focus on drug discovery, rather than pure scientific research. They plan to create a fully staffed, fully equipped drug design port that would allow open access for qualified researchers in Florida. These design ports would allow researchers to convert their findings into new drug discoveries. Additionally, he said Scripps would provide joint degree programs for all of Florida’s universities.

Suspended Animation Inc., located in Boca Raton, is about 30 miles south of Palm Beach. It’s too early to tell how much SA would benefit directly or indirectly from the Scripps facility. Adapted from St Petersburg Times and FLORIDA TODAY

_________________________________

THE END OF FUTURISM?

The day was, a few decades ago when the prognostications of the World Future Society, (WFS) were valued by Presidents, politicians and the media alike. But over the years, time has taken it’s toll of the movement.

Mike Marien, an outspoken critic of the field said "Everybody’s more specialized, so there isn’t a market for anyone who can speak about large holistic matters with any authority." The Society’s membership rolls are down ten percent from ten years ago. An WFS member hasn’t been invited to the White House since Ronald Reagan was President. Long gone are the days when Isaac Asimov, Buckminster Fuller, and Arthur C. Clarke made headlines with their prophesies.

Ed Cornish, 76 and founder of the movement in 1966, works on a computer- a DOS machine that doesn’t do e-mail, the net or Windows. Recently, a staffer said to his boss "A Seattle radio station called, wants to know if you have some predictions for next year." Cornish thought a bit, then said, "I can’t think of anything in particular."

Futurism is doomed for a number of reasons. For starters, we now have a plethora of niche consultants, and a booming field called risk analysis, which uses proven actuarial methods. We’ve wised up to the fact that futurism as a discipline is a bit of a con. They examine trends, and play out what if scenarios. Anyone with a dial-up connection can do it.

Finally, there’s a trail of forty years of failed predictions. Consider a recent one: Watts Wacker, a well know futurist consultant predicted in 1999 that the U.S. Postal Service would offer free e-mail accounts within two years. He said USPS had the ideas and the will to make it happen, that "they’ve done their homework." Four years later, when Gerry McKiernan, Director of Media Relations for USPS was asked about it, he said, "this is the first I’ve heard about it." "If we don’t sell stamps, we don’t pay our employees." Apparently Wacker hadn’t done his homework.

When enough predictions are made, some are bound to be right. A few futurists, (and Wacker in 1997) predicted that terrorists might someday hijack a plane and crash it into a building. But by 1996 Tom Clancy had already written two books based on that premise! Adapted from WIRED

___________________________

TRANSVISION 2004: Date Change

Please note the date change for TransVision 2004: August 6-8, 2004

TransVision 2004: Art and Life in the Posthuman Era, JJR McLeod Auditorium, University of Toronto, Toronto, Ontario, Canada

Call for Proposals

Deadline: April 15, 2004

Include all of the following information in a two-page proposal for your presentation:

- Title of presentation

- Type of presentation (i.e. talk, performance, exhibit, video, etc.)

- Program track to which topic relates:

- Transhuman Art and Culture

- Transhuman Science and Technology

- Transhuman Ethics, Law, and Politics

- Other (see list of suggested topics for examples at the TV04 Website)

- Objective(s) of the presentation

- Description of the content and format (300 words or less)

- Abstract (25 - 50 words) for inclusion in the conference program

- Presentation space requirements, media to be used and audiovisual equipment needed (if any).

- Designated contact person (only one per proposal)

- Complete name, title, organization, address, phone and fax numbers, and e-mail address for each session presenter

- Brief biographical sketch (50-100 words) of each presenter

Please submit your proposals electronically to World Transhumanist Association secretary James Hughes Ph.D. at james.hughes@.... If necessary, you may submit your conference proposal to Dr. Hughes by mailing it to him at: Trinity College, 71 Vernon St., Hartford CT 06106, or by faxing it to: (860) 297-4079.Deadline for submissions is April 15, 2004. Please attach the paper the presentation is based on if it is already written.

After notification of acceptance of your paper, all presenters (at least one per presentation) will be required to pre-register for the conference. Presenters not registered by June 15, 2004 will not be included in the program.

For more information see the conference website at http://www.transhumanism.org/tv/2004

Proposal Selection Criteria

Proposals will be selected based on the following criteria:

- A clear and concise description of the proposed presentation

- Relevance to conference goals and objectives

- Evidence of presenter experience with topic

- Completion of all information requested

Timeline

- Proposals due by: April 15, 2004

- Notification of acceptance: May 15, 2004

- Deadline for conferees to pre-register: June 15, 2004

Publication of Proceedings

If your presentation is accepted, you are strongly encouraged to submit it as an electronic text by June 15, 2004. - Some of the audio, graphic and film material will appear in the WTA's online gallery of transhumanist art

George Dvorsky

sendev@...


LIFELINE NUTRACEUTICALS, INC.

Contact: Bill Driscoll, President/CEO

Tel: 720-488-1711

billdriscoll@...

http://www.lifelinenutraceuticals.com

FOR IMMEDIATE RELEASE

Lifeline Nutraceuticals, Inc. and CereMedix, Inc. sign an Exclusive Worldwide Licensing Agreement for the development of a novel technology-driven Anti-Aging Dietary Supplement

DENVER, COLORADO AND WORCESTER, MASSACHUSETTS, OCT. 16, 2003. Lifeline Nutraceuticals, Inc. and CereMedix, Inc. announced today that Lifeline has licensed exclusive, worldwide rights to an innovative oral dietary supplement that is being heralded as the first serious product candidate in the battle against oxidative stress. Oxidative stress is widely known to play a key role in over 100 age-related diseases and the aging process itself. This patented and proprietary product, currently known as CMX-1152, has been licensed from its inventor, CereMedix Inc., a Worcester-based biotechnology company. CMX-1152 is one of the products resulting from over 20 years of scientific research by CereMedix founding scientist, Dr. Victor Shashoua and has received much international media and scientific community attention recently as a "break-through" anti-aging product. So significant is this advance in anti-aging technology that a nationally-syndicated television news magazine recently interviewed Lifeline's President, Bill Driscoll, with the intention of publishing a feature story on CMX-1152 in the coming months.

A TRULY UNIQUE APPROACH

CMX-1152 represents a major leap forward in terms of dietary products designed to deliver anti-oxidants to the human body. Instead of pumping the body full of difficult to digest, largely un-absorbable, and generally ineffective exogenous oxygen scavengers, Lifeline's revolutionary product increases the body's production of its own natural antioxidants using a proprietary, patented peptide derived from a protein that occurs naturally in the human brain. This is believed to be a truly unique approach unlike anything else in the anti-aging, antioxidant field. CMX-1152 acts by mobilizing the body's own "defense and repair" mechanisms, including stimulating the production of the body's primary natural antioxidant enzymes. The result is the rescue of tissues and organs that would otherwise be irrevocably damaged by the effects of oxidative stress.

PROVEN BY INDEPENDENT LAB TESTS…

Independent laboratory analysis has already demonstrated encouraging corroboration of CereMedix's own research, indicating that CMX-1152 up-regulates key antioxidant enzymes by more than 400% above normal levels. In other studies, rats that suffered ischemic strokes were given CMX-1152 and the effects of the strokes were almost completely reversed. Similarly, geriatric mice that received the drug showed significant signs of returning youthfulness. "It's hard to effectively put into words the importance of this licensing agreement for CMX-1152," said Mr. Driscoll. "Lifeline now has the opportunity to develop the solution to a major human need, while also developing a multi-billion dollar product which could bring hope to hundreds of millions of people worldwide who might otherwise prematurely age due to the incredible ravages to their bodies caused by free radicals and oxidation." "We are confident that we have chosen the right partner to effectively bring this unique, revolutionary product to market," said CereMedix President and CEO, Steve Parkinson. "Lifeline has ambitious plans to see that the benefits of CMX-1152 can serve human needs all around the world," Mr. Parkinson continued. "We sought a partner that recognized that CMX-1152 is not like any conventional

dietary supplement and consequently would make this unique platform of using the natural biology of the body to heal itself the focus of its marketing platform." Clinical trials, for CMX-1152 as an over-the-counter oral supplement, are expected to be completed by the end of the first quarter of 2004. Lifeline intends to start marketing the product, under a yet-to-be-determined brand name, in the second quarter of 2004. In the meantime, Lifeline is preparing to take advantage of its very unique competitive advantage in a huge market.

ABOUT THE US DIETARY SUPPLEMENT MARKET…

In 2001, the Nutrition Business Journal estimated the total sales of dietary supplements to be a staggering $17.8 billion dollars. In an attempt to hold off the onslaught of aging, $5 billion is spent annually on anti-aging products in the US alone, with more than $2 billion of that directly attributable to antioxidant supplements. Unfortunately, these supplements cannot substitute for the effectiveness of the body's natural antioxidants, due to dosage limitations, digestive tract barriers, poor absorption rates and inability to affect the body at the intra-cellular level. CMX-1152, it is believed, overcomes all these barriers through its unique mode of action in up-regulating the body's own antioxidant system.

ABOUT LIFELINE NUTRACEUTICALS…

Lifeline is a privately held, Denver-based company whose principle business is the manufacture, marketing and distribution of dietary supplements. Lifeline Nutraceutical's initial product and marketing focus is exclusively on its CMX-1152 product. Lifeline has already commenced discussions with major corporations regarding sub-license agreements and other collaborative arrangements in order to aggressively bring CMX-1152 to the global market. For more information, please contact Bill Driscoll at 720-488-1711 or billdriscoll@...

ABOUT CEREMEDIX…

CereMedix is a privately held development stage biotechnology company with a novel genetics-based technology platform and several drugs in development. The company's technology is founded on a patented discovery by Dr. Victor E. Shashoua of a family of peptides that can up-regulate endogenous human genes which express enzymes and growth factors. These enzymes and growth factors can defend and repair cells and tissues against oxidative damage caused by aging and numerous disease conditions. CereMedix believes its unique approach to health care in utilizing natural healing properties of the body heralds the future of medicine. The company's candidate product portfolio includes potential drugs for pre-treatment of cardiac surgery-related trauma, chronic obstructive pulmonary disease (COPD), ischemic stroke, Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis (ALS), Huntington's disease, AIDS-related dementia, myocardial infarction, and multiple anti-aging indications. The company's most advanced therapeutic is an acute treatment that can reduce and protect against some of the damage caused by the trauma, including oxidative stress, of cardiac surgery and in particular artery bypass surgery. This drug candidate is expected to enter human clinical trials next year.


QUICKIES

Life is like an escalator, you can move forward or backward, but you can’t remain still. Patricia Russell-McCloud, Motivational speaker.

American soldiers today are twice as likely to survive combat wounds as those during WWII. But DARPA, the Defense Department’s research branch hopes to keep them fighting longer. One of the groups goals is to keep wounded soldiers pulling the trigger for up to four days without a medic or evacuation. One avenue of research is developing a smart bandage that delivers tiny electrical shocks to accelerate tissue repair. Adapted from WIRED

New on the market: Colgate Orabase Soothe-N-Seal. A gel-style resin that incorporates a painkiller and an anti-inflammatory. Intended to treat canker sores. Band Aid Liquid Bandage A consumer version of Dermabond. Forms a waterproof seal on skin. Comes off by itself after five days. Ibid

It’s not clear how much sleep the Army thinks wounded soldiers need, but if they’re not wounded, the Army’s goal is to keep them awake for seven days without sleep. Currently, the US Army’s Aero- medical Research Laboratory is testing an anti-sleep agent called modafinil. Sold by Cephalon under the name Provigil, the compound can keep users up for two or three days at a stretch, without side-effects. Ibid

In the past, we’ve reported here on the ingenious ways funeral homes respond to the needs of their customers. It turns out that one of the most fail safe growth industries today is oversize caskets for obese people. The Goliath Casket Co. of Lynn, Indiana can’t build them fast enough. When Keith and Julane Davis started the company in the late 80’s, they sold just one triple wide, their biggest model, each year. Now they’re shipping 4 to 5 triple wides a month. Business is increasing 20% annually. San Francisco Chronicle


 

A Guide to AntiAging Drugs

By Thomas Donaldson, Ph.D.

The American Cryonics Society ("ACS") has made arrangements with long time cryonicist Thomas Donaldson to publish and distribute his latest edition of A Guide to AntiAging Drugs. Dr. Donaldson has studied the affects of various drugs and food supplements on longevity for many years. He has written extensively for cryonics magazines and publishes "Periastron," a news magazine that centers on brain research.

Thomas Donaldson first published A Guide to AntiAging Drugs in 1994 in a loose-leaf binder format. This format allows the owner to replace pages that are updated by Thomas as new information becomes available. When additional experiments and studies provide new information, Thomas can send the book-owner this supplemental information. Thus, the guide is the last antiaging book that the reader needs to buy!

ACS plans to sell the "Guide" on its website (www.AmericanCryonics.org) for $36.24
(CA residents add $2.67 for sales tax with a total of $38.91).

Our special price to ACS members & for this mailing is $30.69
(CA residents add $2.22 for sales tax with a total of $32.91).

The book-owner may then subscribe to Dr. Donaldson’s Update Service

for an additional $5 sent directly to him.:

Introduction: Why we must do it ourselves?

Chapter 13: Coenzyme Q10, Improving our

Chapter 1: A Short Survey of AntiAging Drugs

Immune Systems

Chapter 2: Antioxidants as Drugs Against Aging

Chapter 14: Human Growth Hormone,

Chapter 3: Cysteine and SH-Groups

Outgrowing Aging

Chapter 4: Pantothenate, a Vitamin that May Work

Chapter 15: Extracts of Ginkgo biloba: Extracting

Chapter 5: And Pyridoxine (Vitamin B6) is Another

Old Age?

Chapter 6: Procaine, the Famous One

Postscript: What These Drugs May Tell Us, and

Chapter 7: Deanol, a Test Case for Antiaging Drugs

More

Chapter 8: Deprenyl, a New Drug Against Aging

Appendix 1: Biochemistry and the Action of

Chapter 9: Levodopa, the Hard Stuff

Drugs

Chapter 10: Melatonin, Changes in the Night

Appendix 2: Drugs Waiting in the Wings

Chapter 11: Phenformin and Phenytoin, Two

Appendix 3: Some Suppliers of Antiaging Drugs

Drugs to Watch

Appendix 4: Not Against Aging. Two Popular

Chapter 12: Chromium, Shining Away the Sugar

Drugs Failing the Lifespan Test

Here is the table of contents:

" *Please allow 2-3 weeks for your order to arrive.

MAIL ORDER FORM

Name

 

Address

 

City

State

Zip

 

Telephone

E-mail

 

 

 

Mail to: American Cryonics Society

P.O. Box 1509

Cupertino, CA 95015

 

Christopher Reeve’s Quest

Christopher Reeve’s will and determination should be an inspiration to disabled people and cryonicists alike. For the disabled, it’s the improvments in his spinal cord injury since his accident that have confounded medical experts, for cryonicists, it’s the knowledge that medical professsionals are a long way from fully knowing the true damage done by freezing and warm ischemia.

It has been eight years since Christopher Reeve broke his neck at an equestrian competition in Culpepper, Virginia. After his horse stopped suddenly before an obstacle, Reeve flipped forward and suffered what doctor’s call a "hangmans injury." Death by hanging often results from suffocation. After the accident Reeve was heard to say "I can’t breathe."

Reeve’s injury left him paralyzed from the shoulders down. He was unable to breathe on his own. Doctors immediately placed him on a ventilator. He was informed that his injury was permanent, and that he would no longer feel sensation in ninety percent of his body. Reeve stated "I was told from the start that it was hopeless, that it was impossible for me to regain movement below the shoulders."

He said that "every scientist should remove the word ‘impossible’ from his lexicon." Not only does Reeve want to cure himself, he is determined to transform medical research which he feels is constrained by excessive caution. "Research should not be reckless, but it should be fearless. If you don’t add courage to the equation, the scientific aspect will go to waste."

Up to now, Reeve’s progress has been remarkable. He’s able to use the biceps of his right arm against resistance. When in a swimming pool, he’s able to push himself off with his legs.

"One day I expect to get up from this wheelchair." This claim, which he’s often made in speeches has not been well received by certain scientists and advocates for the disabled. Some critics claim he’s in a state of denial, others have called him a spoiled celebrity who raises false hopes.

Charles Krauthammer, a prominent columnist, who’s also wheelchair bound and has a medical degree, wrote an angry appraisal of Reeve after the actor appeared in a TV commercial touting advances in spinal cord research.

Reeve is aware that his intention to recover has been dismissed, even denigrated. Yet he is not as naive as some of his doubters think. Reeve has a dogged intelligence, and in the past eight years he has developed a nuanced understanding of the biology of spinal-cord injury, he has learned how the scientific establishment sets priorities and conducts its research; and he has deciphered the ways that different branches of the government permit or bar innovative medical treatments.

Reeve knows that his fame gives him unique access to the media, to politicians, and to fund-raising dollars. By exploiting these resources, he has set out to change the way things are done in the clinic, the laboratory, and the government. He believes that only by causing a revolution in all three realms does he have a chance.

It is perhaps easy to view Reeve's quest as one driven by hubris; it is far from certain that he will walk again. However, the steady, incremental progress he has made is extraordinary and, to many scientists, confounding. Indeed, ,the results have been so encouraging that mainstream researchers are reconsidering the dogma that long-term paralysis is irreversible-and paralyzed patients around the world are beginning to follow Reeve's lead.

He considered suicide, but his wife Dana helped change his mind. "Chris had to make his own decision," she said. "I was very clear that I was in it for the long haul. I said, "you’re still you, and I love you. Let's give it two years, and if in that time life is too agonizing let's reevaluate."'

Nearly everything that Reeve read asserted that patients like him could not improve. He eventually discovered, how ever, that a few physicians and neuroscientists had taken a contrarian position. One was V. R. Edgerton, a neuroscientist at U.C.L.A. Edgerton had theorized in the early eighties that the spinal cord could function independently of the brain. This was at odds with the prevailing view that the spinal cord was merely a cable connecting brain and body.

"When scientists think they know how something works, it becomes difficult to get new ideas accepted," Edgerton told me. Virtually no decent scientist would study spinal-cord injury. "The dominant view was: it's a hopeless situation," he said. "Spinal-cord-injury research was considered 'the graveyard of neurobiology."

Edgerton began experimenting with cats whose spinal cords had been cut with a scalpel midway down their backs. The injured cats were placed in a harness and put on a treadmill. The idea was to make the cats mimic normal walking, to see if inducing such repetitive activity could reawaken circuits that Edgerton believed had been shut down by the injury. The experiment was a success: after using the treadmill for three to six months, most of the cats could walk again.

Werriig's experiment was inspired by the observation that when newborn babies are held upright, their toes touching the ground, they spontaneously move their feet in a stepping motion. To him, this suggested that there was an innate 'program 'within the human spinal cord for walking; perhaps this program could be retrieved, like an intact file on a damaged hard drive.

In November, at a conference in New Orleans, Reeve met with John McDonald, an ambitious spinal-cord researcher at Washington University in St. Louis. McDonald agreed to supervise his therapy, and that winter, for the first time since his accident, Reeve entered a swimming pool.

Around this time, Reeve found that he could wiggle the toes on his left foot. 'The sequence didn't make any sense," he said. 'So I thought, why shouldn’t I try everything?" In 2001, Reeve discovered that he could move his right leg slightly when lying on his back- His left leg revived next. Finally, Reeve's arms started to respond; he still can't lift them while sitting up, but his exercises in the pool are making them stronger. His workouts are now so rigorous, , that he often feels muscle burn afterward.

McDonald's association with Reeve has allowed him to create a flourishing rehabilitation institute in St. Louis. Forty patients are now undergoing treatment. McDonald recently started a pediatric program. "I credit Chris with leading me down this path, he has said.

In 2001, McDonald began studying groups of paralyzed patients. He discovered that patients who used the electrical- stimulation bike had fewer pressure sores, blood clots, and infections. "The best way to avoid skin breakdown is put two inches of muscle on your buttocks," McDonald said. "The best way to build bone density is to put radial forces on bone. The bike is the best way to do that."

Critics note that Reeve has financial resources that far exceed those of ordinary families. When asked how he pays for the team of eighteen people, from nurses to physical therapists, who regularly assist him. (His annual medical expenses exceed five hundred thou- sand dollars a year; his insurance covers two-thirds of that.)

Before the accident, Reeve explained, he was a member of three unions, and his disability benefits were unusually large, totaling some four million dollars. He also receives free equipment from manufacturers who hope to draw attention to their products; one company gave him an electrical- stimulation bike, which cost a hundred thousand dollars, for home use.

Reeve is unapologetic about mobilizing his resources to sustain his life and spur his recovery. He points out that he has worked tirelessly to encourage bold scientific research. To help ordinary families, he argues, exotic experiments need to become everyday procedures. And Reeve believes that too many researchers lack a sense of urgency.

As Reeve became acquainted with the scientific community, he grew frustrated by the widespread careerism. "Professors with tenure submit a grant application to get a little bit of money to try to have a little bit more success, which would then get them another grant and then another few years to achieve another little bit of success, but not to launch a major presumptive strike to get rid of the whole problem," he said.

Later, he added, 'I want things to happen quickly. I certainly want to benefit within my lifetime. I don’t want to get out of this wheelchair at the age of seventy-five. I am fifty-one, and am now very healthy, and would like to be out of the chair very soon. I'm not willing to resign myself to being an advocate for research that will benefit people only after I'm gone. I'm not that noble." He laughed, but it wasn’t a joke.

Even more controversial, Reeve believes that researchers need to stop being so timid about giving experimental therapies to humans. In the United States a new therapy is typically tested on animals for years before it is tested on humans, and even then it is administered to a slowly growing group.

Most scientists think that this approach protects patients, but Reeve believes that it often harms more than it helps---by slowing science to a crawl.

In our conversation, he described how, in a commencement address at an Ivy League medical school, he had told the students the story of Hans Keirstead, a professor at Irvine. Keirstead, who was working with human embryonic stem cells, had designed a treatment protocol that shortened the three stages of a traditional clinical trial to two stages. 'I said to the audience, 'This is how these young guys are thinking. This is a young scientist who really wants to make a difference. What he did was truly commendable,'" Reeve recalled

Afterward, he went on, This tenured professor said to me, "That is very disturbing. It's very upsetting, because thats rushing things, and if one mistake is made it could set the whole field back ten years."

Reeve replied, "It might be upsetting to you, because it's not the way you are used to thinking. But it’s not upsetting  to me as a patient. Because, let's face it, nothing of any significance has ever been achieved without reasonable risk."

"Early results have been promising, however, and nobody appears to have been harmed. In October, Wise Young, the researcher at Rutgers, traveled to Beijing to examine Huang's patients. "I saw this with my own eyes," he told me. No one should view Huang’s protocol as miraculous, Young said, "but it is bringing back sensation and some motor function." All the patients in Huang's study had chronic injuries, he said; on average, they had been paralyzed for two years. "One very puzzling thing is that many of the patients are recovering function within three to five days, which is too fast for regeneration," Young added. "There may be some other mechanism of recovery that we don’t understand.'

Reeeve is even more excited by the work of Dr. Hongyun Huang, a Chinese neurosurgeon. Huang, making a leap that Reeve applauds and others condemn, has injected olfactory glial cells into the spinal cords of nearly four hundred paralyzed patients, including three Americans. Huang obtained the glial cells from aborted human fetuses. (Such fetal-tissue research is banned in some U.S. states, and the Bush Administration supports a federal ban.)

The speed with which Huang has moved to clinical trials has stunned many in the West. Some scientists, such as Ram6n-Cueto, think it is important to do more research first; she is determined to do primate trials of her method before proposing human studies. Given that scientists do not yet fully understand why glial-cell implantation works in rats, the F.D.A. would also, likely have been wary of green lighting Huang's study.

Since news of Huangs success leaked out on Internet discussion groups, thousands of desperate patients have contacted him. Huang has set up a program that allows Americans and other non-Chinese to visit Beijing for one month, for surgery and preliminary rehabilitation. The cost is twenty thousand dollars; six thousand people, Huang says, are now on a waiting list for the program.

Young, who has created a Web site, Sciwire.com, to dispel rumors overstating the promise of new methods, tells patients who ask about Huang's trial to wait for more data. "But there is no way

you can talk these people out of doing it," he said. "You can tell them wait another year until the paper has come out and maybe he’ll come to the states and they say, Hey, I don’t want to wait three or four years to try this."'

When asked what part of his rehabilitation he treasured most, he replied " The warmth of human skin was the sensation he valued most. Feeling my children’s touch again—that’s been the most amazing thing. Adapted from The New Yorker


CI ONLINE DISCUSSION GROUP

The Cryonics Institute recently instituted an online discussion group for CI members. {Cryonics_Institute@yahoogroups.com}

The forum has attracted a number of participants, and from them one senses a sense of frustration at not being given the necessary support in making local suspension arrangements and being able to communicate with other local CI members, for assistance in an emergency. What follows are a few representative messages. With the exception of Robert Ettinger, Ben Best, and James Swayze, only initials are used. While acknowledging that CI has some shortcomings, and indicating some changes will be made, Robert Ettinger and Ben Best also offer a bit of reality.

_________________________________

From BN

To: Ettinger@...

Bob,

I must say that CI’s current procedures for getting a member from A) initial sign up to B) ready to be suspended by a local funeral director, is inadequate.  What is missing is a "Member’s Guidelines to Establishing a Cooperating Funeral Director." 

 

I consider myself to be a pretty practical guy, a program manager by profession, coordinating relationships and logistics in an engineering environment.  But I am at a loss to see how to effectively proceed to get a funeral director’s cooperation.  If I am having these difficulties, I can only imagine what other CI members, who are less practically inclined, must be going through.  I imagine, that like me, many or most never contact a local funeral director and, like me, remain unprepared for a satisfactory deanimation.

 

Reading CI publications leads a perspective member to believe that becoming a member includes access to a network of cooperating funeral directors, trained and ready to perform surgery when you deanimate.  In reality, when you join as a member, you are probably not near a participating director and in that case you are on your own to figure out how to establish one (and to pay for equipment and annual retainers?). Most helpful would be a "Member’s Guidelines to Establishing a Cooperating Funeral Director" that covers the following:

 

* Various levels of funeral director support provided, from cooling and shipping, to cooling, CPR, profusion, and shipping.

 

* Strategies for establishing a good relationship with a funeral director, including things to look for in comparative shopping, questions and comments to make on initial contact, fees the member may have to pay the funeral director, options for members to supply the funeral director with equipment, annual procedures to ensure continued cooperation, etc.

 

* Some examples of real life cases of enlisting funeral directors.

 

* A web page of names and locations of funeral directors currently cooperating with CI. 

 

It would also be very nice if CI offered a "Funeral Director Maintenance Plan" where for, say, $5,000, CI establishes the local director and supplies him with necessary materials, and for, say, $1000/yr, CI will give the director an annual refresher course.

 

You see the problem is, I am short on time, and this means it will be very easy to let this critical step of entering stasis, deteriorate to unsatisfactory levels.

_______________________________ 

 

From: Ben Best

A number of people on this list have

expressed concern over their isolation and have requested information about other CI members living in their area. While it is desirable to put people in contact with each other, CI cannot give-out information about members without the permission of those members.

I have seen first-hand (in Toronto) the

benefits of members of different cryonics organizations working together in a local group. Cryonicists are few and far between so it makes sense for them to work together in areas distant from the main headquarters of their organization even when the organizations are different. Such cooperation was agreed-to in the CryoSummit of August 2002.

I have recently spoken to Jerry Lemler and Tanya Jones of Alcor about the idea of a consolidated list of contact information about cryonicists. American Cryonics Society members would also be welcome on such a list. But the issue of

confidentiality remains.

In order to publish contact information about CI members we would need another piece of paperwork from the members (signed/witnessed/notarized) authorizing such disclosure. I support the inclusion of this paperwork in our documentation, but I suspect it will be months before even as many as 20% of our members have returned this document. To complicate matters further, there would probably be CI, ACS or Alcor members who would be willing to disclose contact informattion only if it was part of a list that did not include members of other organizations. There would also be members who would object to any publication of their name and e-mail address on the web -- even if not in computer-readable form -- because diligent spammers could transcribe the information.

Despite all these complications, I want the CI paperwork to soon include a document that authorizes (or prohibits) disclosure of member contact information-- either on the web or as a booklet. The default, of course, is to prohibit disclosure.

Along the same lines, I would also like paperwork to authorize public disclosure of cryonics arrangements and cryopreservation details. Without this document we will continue to assume confidentiality. But the more people are open about their cryonics arrangements and the more often prominent community members are seen as having made such arrangements, the sooner cryonics will

be accepted as a respectable alternative to burial and cremation.

Ben Best

_________________________________

From HD

KW wrote

This is in response to James Noel. I appear to be the only person in my state registered with CI. I have yet to contact my local funeral director due to business but mostly due to: How in the world do I even go about that conversation?

While I like all the ideas I have seen proposed and would certainly be interested in assisting in some regional way perhaps, while we are waiting, do you think you (or anyone else) could simply give some of us more shy and not too sure what to say folks an idea how you approached the funeral director? I live in a very small town and I also work with the police department so I am concerned about getting things set up in case I am involved in an accident. But, I don't want to muss up the exchange with either one of the two funeral homes here. A talk track? A snazzy introduction? Better to visit in person or do it over the phone? Maybe this is silly but I really just am not sure how to even start. If you have any advice so those of us who want to get started can go ahead and don't delay while all the nifty ideas y'all proposed come to fruition. I would even be interested in "whatever you do DON'T say this..." types of responses from those with experience!

Thanks in advance,

KW

Hello KW,

We also live in a small town and had the same initial concerns.

When my wife recently had major surgery, I arranged to have my local funeral director stand by with me in the waiting room during the procedure. I had spoken with him several days earlier re the situation, our CI contracts, had him call CI for details & procedure, and, of course, settled on the amount of compensation for his time and preparation.

Our first conversation in his office began thusly; "Larry, as a funeral director, I am sure you are more aware than most that we, each of us, have to face our own mortality in our own way. This is *our* way."

He was most receptive. He probably considers us a religious variant, no more peculiar than Buddhists, Hindus, Catholics, or the dozens (this is Central Texas) of Protestant flavors that comprise his clientele. Tolerance is essential in his business. As is confidentiality. Not to worry!

HD

_________________________________

From EN

I don't know what would be involved in the way of time and effort required for a secure directory with controlled access. Perhaps Ben could shed some light on it.

_________________________________

From ST

I am with you on this. The way I found the only other cryonicist in my area was by letting Andy know that it was okay for him to give him my contact information. This worked out very well, and we are talking about forming an informal support group here. I have a few friends that are in the process of signing up, so there should be four of us soon, with contracts in this area. We've also managed to secure local funeral home's assistance, although I will feel more comfortable with them when they see there are more of us.

I would not want my real name or information given out on a public list either, but I like your idea.

Sincerely,

ST

________________________________

From JC

Fellow Cryonicists of all organizations:

I need help with regard to my geographical location.

I have no disabilities, Indeed I have no health problems at all, but I am 82 years old. I did have a serious stroke 6 years ago from which I recovered completely. There have been no recurrences.

I live in the Las Vegas area and there is no cryonics support capability that I know of anywhere near here.

Because of my advanced age, my wife Ellie and I plan to move by the end of 2004. I'd like information and recommendations about locations which are populated by other cryonicists; so that when I do eventually approach death there will be knowledgeable support

in my area; including the capability for rapid-reaction preparation and transport of a near-death or newly-dead person.

I have lived in Chicago and I grew up in St. Louis so I know the general climate of the region. I would prefer not to live in the Detroit area because of its similar climate. (However, I would elect to live in the Detroit area if that were the only area of the type that I describe herein). I know that there are "collections" of cryonicists in Arizona and in Florida, but I don't know exactly where or how many

and which ones are best prepared for mutually cooperative "prep" activities. Also, are there other areas besides those two which are "cryonicist-friendly"? All-things-being-equal, we prefer Arizona,

I would be happy to contribute a nominal monthly fee, a subject that was discussed in the referenced issue, to maintain some kind of "standby" capability. I would also be happy to actively participate in the preparation of those in the area who deanimate ahead of me; And I would be willing to perform other supportive tasks on a limited, part-time basis. Finally, my wife is much younger than I so she wishes to continue working. Any help in deciding my move and any suggestions will be appreciated.

JC

________________________________

From JN

I would highly recommend you relocate to the Scottsdale, AZ area. It has the Alcor Company there as well as a very good CI friendly funeral home. You may wish to contact CI for the funeral home point of contact information. Scottsdale is an upscale community with a lot of the amenities of Las Vegas including fine healthcare facilities as well.

I presently live in Yuma AZ, the pits for both funeral and medical services, and plan to eventually move to Scottsdale. I'm 61, but am gainfully employed here in Yuma until retirement, another 4 years.

I realize I'm taking my chances, but am willing to do so by living here in such a remote area. I do have a friend with a CI contract in my area which is helpful. At 82, you would want to be close to either CI, or at least an Alcor. CI and Alcor both have the needed supplies available and close at hand, and have cooperated on a limited basis.

So, my best recommendation is Scottsdale Phoenix areas, if you desire a climate similar to Las Vegas, and want to remain close to the facilities to provide cryonic suspension with the fastest response times.

________________________________

Ben Best wrote

This year has been a busier than normal one for the Cryonics Institute -- about 6 cases so far in 2003. This would mean that perhaps 6 funeral directors out of many thousands had a single cryonics case so far this year. Our list of funeral directors who have had cryonics experience is thus a small one and quickly becomes out-of-date. The big exception is our local funeral director Jim Walsh who helps with a large portion of the cases.

Is it really worth the time & energy of a funeral director to stock current CI materials in case of an *unexpected* cryonics emergency? Worse, will a funeral director who expends time & energy on something that never materializes be left with a negative impression of cryonics?

In most cases I think it is best to actively involve funeral directors only when there is a real prospect of business for them. In practice it has not been difficult to find cooperative funeral directors

when there *is* the real prospect of business. "

_________________________________

From JS

Ben is absolutely right on this point, and I should have been clearer. If in the future (hopefully) cryonics becomes significantly more popular (with at least 100 times more signed-up members overall), then it would become profitable for funeral directors to advertise the service along with their other (standard) services. I agree that this would not be a reasonable course right now.

However, I am suggesting that as soon as a member does have a full paid contract, that C.I. should be pro-active. They should first check with the member and ask him if he wants them to find a cooperating Home, or if he would like to try first. If not, they should immediately check on the availability of a cooperative funeral home in that member's area, especially if there are no previously signed members from that area.

They should verify by direct communication with the Home, the capabilities of that establishment and let the signed up member know (at least within one month of sign-up) if the Home will handle cool-down, perfusion, and shipping of a member, and that it pledges to have on hand the proper perfusion materials supplied by C.I. The Home should establish a reasonable price for the storage of the materials for the customer. C.I

should let the member know when the materials are shipped. If no fully cooperating director or home can be found, C.I. should notify the member of the situation and work with him/her to find the closest service in a neighboring town.

So what I really meant by a official list of cooperating funeral directors, is one for cities where there already is at least one fully signed up member.

I think that the idea of having a booth at a Funeral Trade show is an excellent idea. It helps persuade the attending directors that we "fit in" to an existing familiar framework of products and services.

JS.

_________________________________

From JS

DEAR BEN;

HAVE CREATED WEB SIGHT FOR MY GROUP-WWW.METROPOLITANFUTURIST.COM-ANY FEEDBACK NYC LET ME KNOW! IF I DONT GET INFO WILL CONTINUE ON OWN. JIM SUTTON JSUTON5@...

________________________________

From JS

Another post to this Yahoo list re-emphasizes the importance of creating an official list or network of co-operating mortuaries and funeral homes, who meet some standard or standards of support, such as having the current materials supplied by C. I. on hand, having verified that they know how to prepare the patient, etc.

From Ben Best

JS is a very welcome member on this list. I am very impressed by his can-do engineering approach which seems to cover every angle.

But I think he missed an angle or two. When I became active in cryonics in the early 1990s for several years I attended the annual banquet of funeral directors in the Toronto area. Many showed varying degrees of interest in cryonics, but a very few were hostile to the idea.

I subscribed to the two Canadian funeral director journals and wrote a cryonics piece for one of them -- CANADIAN FUNERAL DIRECTOR magazine. Nothing much came of these activities except that I may have had a tiny voice of support for the removal of the requirement for embalming of bodies shipped out of the Province of Ontario.

I visited Barry Albin at his establishment in the UK. Before the Larry Johnson fiasco, cryonics has been mostly a "man bites dog" story for the media -- an entertaining oddity. Albin has gotten more than his share of press coverage because of his high-profile willingness to help with cryonics cases, despite his personal lack of belief in the value of the procedure.

I also spoke with a funeral employee who had sacrificed several working days to take Mike Darwin's training course in the early 1990s. The man was extremely bitter at having wasted his time & money in getting trained for something he never once used. It was about 13 years ago that Alan Sinclair opened a fully-equipped (complete with ambulance) cryonics facility for the UK. Since that time there has been exactly one cryonics case involving a British person living in the UK.

I took the initiative 4 years ago to find out which ones in the Austin area would do this to protect the interests of my family, but a lot of people will be too shy or inhibited to do what I did, since I have been virtually (my whole life) immune to peer pressure, etc. Thus I strongly urge you to work on the issue of a public or private but official list of cooperating mortuaries.

I can empathize with what John says about shyness --I had to make an effort to overcome it myself. The first cryonics case in Toronto -- in fact the first case ever in the Canadian Province of Ontario -- occurred one year ago (documented on my website at

 http://www.benbest.com/cryonics/toronto.html).

Jim Walsh contacted a local funeral director who agreed to handle the case as long as it did not require cryoprotectant perfusion.

I went through the phone book and compiled a list of small, secular, privately-owned (rather than part of a large chain) funeral homes. I made only a couple of calls and the owners I spoke to were more than willing to help. But when Mr. Walsh offered to train his initial contact in perfusion technique, that man changed his mind and agreed to perfuse.

It may be that the negative publicity associated with Alcor's Larry Johnson problem may make some funeral directors more reluctant to cooperate. Hopefully that will blow-over. Jim Walsh has suggested that CI have a booth at a national funeral director's trade-show and I hope that this is feasible to do in 2004. I think it would improve our image and be a means of making new contacts. Bill Faloon has told me that his advertisements for funeral directors willing to help usually results in a flood of responses. He said some may even be EMTs or paramedics as well.

Again, I think it is best to try to involve funeral directors only when there is an immediate prospect of business. When his wife was appearing to be fatally ill, Robert Ettinger paid a funeral home a $1,000 per year retainer to be supplied with materials and to be trained in rapid & effective response to a cryonics emergency. For those who are willing to spend the money -- or have a good reason to think a deanimation is imminent -- I recommend this approach.

Otherwise, I think the main emphasis of cryonicists should be to build a local support network of cryonicists, friends and relatives.We should educate ourselves in how to help deliver the best cryonics care that we can and train others so that they can help us.

Alan Sinclair and his UK group is my exemplar and I am also proud of the group I have helped build in Toronto. For more suggestions along these lines I recommend looking at my website:

http://www.benbest.com/cryonics/localres.html

"The best can be the enemy of the good".

It is too easy to get discouraged by being overwhelmed by what others have accomplished. Any improvement is an improvement and should not be sneered-at or discounted because others have done better. And every improvement is a step toward another improvement.

Ben Best

_________________________________

From BN

 See my below email and Bob’s response in which Bob Ettinger has put in motion an effort to provide members a "how-to" orientation document for setting up local help.  His suggested timetable of "a few weeks" has likely been delayed due to the legal wrangling going on at CI these days, but I look forward to the document whenever CI gets to it. I’m really glad CI has started this network list.  

 

BN

_________________________________

From: Ettinger@... To: BN

Subject: Re: finding/training a funeral director We will implement your suggestion about a standard instruction -suggestion sheet for members to line up morticians, probably within a few weeks.

Bob 

________________________________

From Robert Ettinger

To: Cryonics_Institute@yahoogroups.com

Responding to some questions raised:

James Swayze has commented, and Ben Best may have more to say, but let me say just a bit about CI and local help for members at a distance, where at least some people seem to have persistent misunderstandings.

First, there is no simple, quick, convenient, turn-key, one-size-fits-all system for your arrangements. The basic CI contract says that our responsibility begins when the patient is delivered to us, and this is the understanding for the minimum suspension fee of $28,000.

Naturally, members at a distance will also need local help and transportation, and this must be arranged and funded.

There are various options, depending on location and circumstances, and somebody has to figure it out and put it in place. In particular, the duties of the local mortician and any possible local volunteers must be spelled out and preparations made, including training and equipment as indicated.

It is more convenient for the member if the local and transport costs can be included in the suspension fee guaranteed to CI, typically through life insurance, so we offer a Local Help Rider along with the Cryonic Suspension Agreement for those who want it. CI then pays the local mortician when the patient has been shipped, according to the terms of the Rider.

The duties assumed by the local mortician, and the price, will vary and require negotiation, perhaps among several parties--the member, CI, perhaps other members in the vicinity, perhaps local volunteers, possibly other cryonics organizations, and the mortician. Finding a willing mortician close enough is usually not difficult, but may take some time.

The whole process will take time and demand attention from our staff, which costs money. Therefore we cannot--as many prospective members would like--get everything neatly lined up to the prospective member's satisfaction before he joins. He must join first, and then we will work with the member and do our best, within our resources and as prompt as feasible, to get all the arrangements in place. If at any point the member is dissatisfied, he can always cancel the contract, if he has one, but cannot recover his membership fee (or dues in the case of an Option Two member).

How local volunteers fit in is highly variable. In England there is a well organized and equipped and trained volunteer group, centered on the initiative of Alan Sinclair (now on the CI Board of Directors) and others. But even this group--let alone others much weaker--cannot represent themselves as agents of CI, for obvious reasons of legal liability. Any involvement of volunteers must be informal from the point of view of CI.

The members who plan to use the group, and the group itself, must see to their own legal protection and make their own judgments as to what is useful and safe. In particular, care must be taken not to get crossed wires between the volunteers and the local mortician.

Members and prospective members must avoid the "us-them" attitude, that "we" (the members) are customers and "they" (CI) are vendors. CI is not a business in the usual sense, and its members are not customers in the usual sense. Obviously this is one of the reasons for the slow growth of cryonics--that it isn't easy, simple, or cheap.

We are trying to make it easier, and in some respects simpler, and at least relatively cheaper, but it won't happen overnight. There is no free lunch. Unless you are rich enough to hire people to do the scut work for you, you will have to put up with inconveniences and tiresome chores.

But you are dealing with chores and inconveniences every day anyway on many levels. At a minimum, you have to run a household with its constant problems and maintenance--it's just the cost of living. With cryonics, you have a chance for a whale of a lot more living with only a moderate dose of inconvenience.

Robert Ettinger

_________________________________

From Ben Best

Thank you for the comments and for the complaints. I do want CI members to complain about perceived shortcomings because that is how we get information about what members want and what we can all do to address problems.

The Local Help Rider states that if a CI member is close to deanimating (or, alas, has deanimated unexpectedly) that CI will use best efforts to find a funeral director who will prepare the patient's body. Recently, as as result of comments in this discussion group, I authorized David Pascal to attempt to contact local funeral directors for members who are not at immediate risk of deanimating, but who want some reassurance that a funeral director will be available if needed.

This service is *not* part of the CI agreement and I authorized David to do it as an experiment in helpfulness for members who don't feel comfortable with contacting funeral directors on their own. I offer no guarantee that this service will continue and I am not really convinced of its value -- suspecting that funeral directors might be irritated by being inconvenienced over matters that will not result in immediate business.

There is a vastly deeper issue to be considered here, however. Too many members think of cryonics arrangements as being like hiring a plumber to fix a broken water pipe.

Minimum funding and minimum effort will give you minimal results. A better analogy for CI is that we are supplying you with lifeboat materials, but it is up to you to use the materials properly and have them available when needed.

Minimum funding of $28,000 (Option One) or $35,000 (Option Two) does not even pay for the services of the funeral director whose help CI will secure. Shipping costs are not paid by CI and a person who lives a great distance from Michigan would be well advised to have Local Help funding to cover shipping costs as well.

If you deanimate in your house unexpectedly or in a motor vehicle accident you can't expect immediate service -- there will be a period of destructive warm ischemia. Ideally you will have family members or friends who will act rapidly in an emergency to cool you down and contact a funeral director. If you live alone you should make some provisions to insure that you cannot deanimate and lie for days without being discovered.

Cryonics organizations cannot be omnipresent or omniscient. Standby services are not part of the CI contract. Alcor gives no more than 3 days of standby without charge --which means you should not deanimate before their team arrives and that it will be costly to deanimate after more than 3 days.

If you want such services with CI you must pay a funeral director extra (as Robert Ettinger did), hire them from an organization like Suspended Animation or arrange a local group of relatives, friends or cryonicists to do standby.

The dirty truth is that the majority of people in all the cryonics organizations die under messy circumstances -- with damage from aging & disease and dying at inconvenient times & places.Life is too vulnerable -- that is our ghastly existential condition. There is no guarantee that cryonics will work even under the best circumstances. But the more we do the better our chances are.

I will do what I can to make CI more omnipresent and omniscient, but it is up to you to try to make up the difference.

Ben


KURZWEIL NEWSLETTER

Source: http://kurzweilainet.net

Published with permission

What is KurzweilAI.Net?

While similar in format to "Nano Girl News," which concentrates on news in the fast developing field of nanotechnology, KurzweilAI.net features the big thoughts of today's big thinkers examining the confluence of accelerating revolutions that are shaping our future world, and the inside story on new technological and social realities from the pioneers actively working in these arenas.

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ISCHEMIA AND REPERFUSION INJURY IN CRYONICS

by Ben Best

INTRODUCTORY REMARKS

Ischemia is the condition suffered by tissues & organs when deprived of blood flow -- mostly the effects of inadequate nutrient & oxygen. Reperfusion injury refers to the tissue damage inflicted when blood flow is restored after an ischemic period of more than about ten minutes. Cryonics patients frequently experience ischemic & reperfusion injury between the time when the heart stops and cryostorage begins.

In this article I attempt to evaluate the nature & extent of ischemic & reperfusion injury in cryonics. I also attempt to assess what can be done to minimize such damage. I focus my attention on ischemic/reperfusion injury to the brain. I rely on peer-reviewed journal articles for information. The single most comprehensive article I have found on ischemic and reperfusion injury is "Ischemic Cell Death in Brain Neurons" by Peter Lipton [PHYSIOLOGICAL REVIEWS 79(4):1431-1568 (1999)]. Most

unreferenced factual statements I make are based on Lipton's review.

ISCHEMIC INJURY

Most of the metabolic energy of neurons is expended on maintaining ion gradients across the cell membrane. A sodium potassium (Na+/K+) pump keeps extracellular potassium low and extracellular sodium high compared to intracellular concentrations. This pump is driven by the energy stored in ATP molecules manufactured in the mitochondria.

Within two minutes without blood flow (due to heart stoppage or blood vessel occlusion) neurons lack the energy to power the sodium/potassium pump. Potassium ions rush out of the cell while sodium & chloride ions rush

inward as the cell membranes depolarize. Neurons attempt to produce ATP by anaerobic glycolysis, resulting in lactic acid. Accumulation of carbon dioxide results in carbonic acid (H2CO3), which further increases acidity. Within two minutes of ischemia, extracellular pH can drop from about 7.3 to about 6.7.

Another ATP-driven pump helps keep extracellular calcium ions (Ca2+) 10,000 times more concentrated than within the cytoplasm. Voltage-gated ion channels and ion-exchangers in the cell membrane also regulate ion concentrations.

Depolarization of presynaptic membranes results in release of the neurotransmitter glutamate. Postsynaptic membranes contain several types of glutamate receptors, notably NMDA & AMPA receptors, which allow calcium ion entry. Postsynaptic membranes contain two voltage-gated calcium channels (L-type & T-type) as well as a sodium calcium exchanger, but the NMDA channel is particularly adept at allowing large amounts of calcium ion to enter the cell.

High levels of intracellular calcium ion activate enzymes (known as calpains) that break down many cell proteins, particularly those in the cytoskeleton. Calcium ion also activates the enzyme phospholipase A2, which attacks cell membrane phospholipids causing the release of arachidonic acid. Activated platelets also release arachidonic acid.

Rupturing of cell membranes can result in leakage of enzymes, notably Lactate DeHydrogenase (LDH). Blood or tissue levels of LDH have often been used as an indicator of cell damage due to ischemic/reperfusion injury.

REPERFUSION INJURY

Restarting blood flow after more than about ten minutes of ischemia is typically more damaging than the ischemia itself because the ischemia sets the stage for oxygen to generate free radicals. Arachidonic acid conversion to eicosanoids can lead to production of the superoxide (O2-.) radical when oxygen is available. Lipid peroxidation chain reactions occur in the membranes of neurons as well as of astrocytes.

Free radical damage to blood vessels is particularly severe. Ischemia results in large amounts of ATP being broken-down to xanthine. Reperfusion allows the endothelial enzyme xanthine oxidase to convert xanthine plus oxygen to superoxide & uric acid. Reperfusion increases the amount of nitric oxide produced by the endothelial cells. The nitric oxide can combine with superoxide to produce peroxynitrite (ONOO-), which is nearly as damaging as the hydroxyl radical. Liberated iron & zinc ions further increase free radical damage.

Neutrophils which have accumulated in blood vessels due to the ischemia can release oxygen-rich free radicals with the availability of oxygen from reperfusion -- thereby attracting more neutrophils. The explosive endothelial cell swelling combined with accumulated leukocytes & blood clots plugging capillaries can result in a "no-reflow" phenomenon -- blocked blood flow.

There is a linear correlation between the amount of reperfusion injury and disruption of the blood-brain barrier. Water flow into the brain leads to edema.

STROKE THERAPY

Can drugs help prevent ischemic damage in cryonics patients? A study of the literature on stroke therapy is instructive.

One might think that drugs blocking calcium ion entry via NMDA receptors would be beneficial for stroke, but clinical trials with these substances have  been a failure. Although animal studies show NMDA-blockers to be effective for the first 4 minutes, after 8 minutes intracellular levels of calcium ion are  the same whether NMDA-blockers are used or not. L-channel blockers (like nimodipine) make no difference.

There are plausible reasons why NMDA-blockers -- even when combined with L-channel blockers -- are of limited usefulness in preventing calcium entry into ischemic cells. Low levels of ATP mean reduced capacity of the calcium-ATP pump to keep calcium out of the cell. High cytoplasmic sodium means high activity of the membrane s dium/calcium exchangers -- particularly those on mitochondrial membranes. Blockage of L-channels leaves T-channels unblocked. And phospholipase breakdown products help to release large amounts of calcium ion which has been bound to the

endoplasmic reticulum.

Animal studies have shown benefit from antioxidants such as Vitamin E

[BRAIN RESEARCH 510:335-338 (1990), melatonin & nifedipine [JOURNAL OF PINEAL RESEARCH 33:87-94 (2002)] and PBN [PNAS 92(11):5057-5061 (1995)] as well as from other neuroprotective agents. But all have thus far

failed to pass clinical trials and be accepted as therapeutic agents. Currently,

the only accepted drugs used for stroke therapy are thrombolytics, anticoagulants and antiplatelet drugs.

Tissue plasminogen activator (tPA) is useful for breaking-up blood clots, but only when given within 3 hours of the onset of stroke. When given within 90 minutes of stroke, tPA more than doubles the 3-month survival of stroke patients [NEUROLOGY 55(11):1649-1655 (2000)]. Prior to tPA, streptokinase & urokinase were the most efficacious thrombolytics. The anticoagulant heparin is given in the hospital and warfarin is used for long-term maintenance.

Aspirin may be used as an antiplatelet agent. These therapies cannot be used for hemorrhagic stroke because they worsen that condition. 

ORGAN TRANSPLANTATION SOLUTION

Some neuroprotective agents that have not passed clinical trials for stroke therapy have shown to be of demonstrable benefit in preservation of organs for transplant. Explanations for the benefits of the ingredients used in the organ preservation solution Viaspan can be found on the Viaspan website (www.viaspan.com).

Allopurinol inhibits xanthine oxidase, blocking the conversion of xanthine & oxygen to superoxide & uric acid. Glutathione is used as an antioxidant with membrane-stabilizing properties. Dexamethasone also stabilizes membranes. Magnesium seems to counteract some of the effects of intracelluar calcium and the sulfate ion resists cell swelling because it is relatively impermeable to cell membranes.

To counteract loss of ATP (Adenosine TriPhosphate), adenosine is added to provide more substrate for ATP synthesis. Monobasic potassium phosphate also supplies substrate for ATP synthesis while opposing acidification and potassium-leakage. Potassium hydroxide also maintains a high pH while opposing potassium-leak.

PREVENTING ISCHEMIC/REPERFUSION INJURY IN CRYONICS

By using a cocktail of agents Mike Darwin and Dr. Steve Harris of Critical Care Research extended the period dogs can tolerate warm (room-temperature) ischemia to 17 minutes. A cocktail of such agents reportedly could never pass FDA approval for stroke therapy or cardiac arrest treatment, hence it did not receive widespread interest or application in conventional medicine. Dogs have a higher heart rate and metabolic rate than do humans. The ischemic tolerance for humans is estimated to be as high as 20 minutes [CRITICAL CARE MEDICINE 16(10):923-941 (1988)].

Under ideal circumstances, however, a cryonics patient experiences little room-temperature ischemia. If cardiopulmonary support and cooling are begun immediately ischemia can be minimized. Under non-ideal circumstances room-temperature ischemia is often considerably more than 17 minutes. It is commonly noted that metabolic rate is halved for every 10ºC drop in temperature. But reducing temperature has a protective effect on the brain which exceeds reduction of metabolism. Experiments on gerbils indicate that a drop in temperature from 37ºC to 31ºC nearly triples the amount of time that neurons can tolerate ischemia [CRITICAL CARE MEDICINE 31(1):255-260 (2003)]. Dogs cooled to 20oC can withstand 60 minutes of ischemia and can withstand 120 minutes of ischemia at 10ºC [CRITICAL CARE MEDICINE 31(5):1523-1531 (2003)].

But if a cryonics patient is given immediate cardiopulmonary support, ischemia can be greatly reduced, if not eliminated. Normal physiologic cerebral blood flow is about 50mL per 100 grams of brain tissue per minute. Good cardiopulmonary support can maintain cerebral blood flow not much higher than 15mL (and usually lower). This is critically close to the 10mL associated with the beginning of irreversible cell damage if such a flow rate is maintained for an extended period [JOURNAL OF NEUROSURGERY 77:169-184 (1992)]. But with effective cooling the flow provided even with

moderately-effective CPR may be adequate to maintain brain structure. Temperature drop is most rapid upon initial application of cooling and there is a natural drop in brain temperature associated with reduced blood flow. Under these circumstances the added benefit of anti-ischemic agents may not be great.

These facts should provide some comfort for those who feel they cannot afford to supplement the cooling and cardiopulmonary support of cryonics rescue with expensive anti-ischemic cocktails. Nonetheless, pretreatment of the patient with aspirin, vitamin E and other anti oxidants is an inexpensive means of reducing ischemia after the heart stops. Such pretreatment may give better antioxidant tissue levels than infusing them after deanimation. Epinephrine has commonly been used to maintain blood pressure and supplement CPR by maintaining blood pressure, although vasopressin may also be used [CRITICAL CARE MEDICINE 30(supplement 4):S157-S161 (2002)].

Pronouncement of death may occur soon after the heart stops. In a do-not resuscitate (DNR) situation rapid application of CPR could easily cause the legally dead person to regain consciousness. It is also seems possible that the heart could restart, but if ischemia has elevated extracellular & plasma potassium levels, the heart is unlikely to restart. The heart rarely restarts without an electonic defibrillation except in young children.

Regaining of consciousness by a cryonics patient would provide reassurance of the effectiveness of the cardiopulmonary support, but it would be traumatic for all concerned -- and a "political" disaster. Barbiturates would be an effective means of maintaining unconsciousness, but as a narcotic its use can be both a political & legal hazard. Fortunately, propofal is not a controlled substance and can keep the patient unconscious. If a funeral director, medical professional or other person can administer heparin, he or she should also be able to administer epinephrine, propofol, a thrombolytic, antioxidants and other agents to combat acidosis.

BRAIN DAMAGE DUE TO ISCHEMIA/REPERFUSION

Nanotechnology may be able to repair freezing damage, but for a brain that has experienced many days of warm ischemia the prospects are not so good. Unlike freezing damage, warm ischemia eventually leads to dissolution of brain tissue into a structureless soup.

On the other hand, claims that a few hours of warm ischemia means

certain loss of personal identity cannot be supported. Even after two hours of warm ischemia (without reperfusion) lysosomal membranes in cat brain cells remain intact [VIRCHOWS ARCHIV B 25:207-220 (1977)]. Monkey brains subjected to an hour of warm ischemia and protected from reperfusion injury show short-term recovery [JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 6(1):15-33 (1986)]. Post-mortem mouse brains subjected to 6 hours of room temperature and another 18 hours at 4oC show half the neurons to be morphologically intact [VIRCHOWS ARCHIV B 63:331-334 (1993)].

The CA1 pyramidal neurons of the hippocampus are often regarded to be the most sensitive to ischemic injury of all neurons. After 30 minutes of ischemia followed by reperfusion, the CA1 neurons invariably die after 2 or 3 days whereas the reputedly resistant striatal neurons begin to die after several hours [ANNALS OF NEUROLOGY 11:491-498 (1982)]. In either case, a cryonics patient should be in a low-temperature condition well before that time.

Cell death by apoptosis ("cell suicide") is a controlled process requiring DNA transcription, new protein synthesis and usually many hours. Apoptosis is probably no ultimate hazard for cryonics patients who deanimate without pre-mortem ischemic damage and who receive prompt cardiopulmonary support & cooldown. Just as future technology may reverse "death" in whole persons, future technology should also be able to reverse much of what passes for irreversible death of cells. Certainly we should expect reversibility from the early stages of apoptosis. Cell death by necrosis is another matter.

CONCLUSIONS

When cardiopulmonary support and cooling are initiated soon after deanimation the use of anti-ischemic agents are probably of marginal benefit. Pretreatment with aspirin and high levels of antioxidants, however, should be easy to do -- and be of benefit. Conditions for

cryopreservation are never optimal and so-called substandard treatment should not be dismissed as being "not worth the effort". Personal identity may well survive considerable ischemic damage. Less damage is better, but not at unlimited cost. Cost/benefit calculations are difficult to make when benefit is so difficult to quantify. The highest priority should be to ensure that death does not strike at times & places that leave one completely unprepared to begin timely cooldown and cardiopulmonary support

CI’s Research Director, Dr. Yuri Pichugin, issued this statement in response to Ben Best’s article:

Ben’s article is good for publication in The Immortalist. Bob Ettinger and I have already written that injuries from freezing and CPA toxicity are much more than injuries from ischemia and reperfusion. Now it is more important for us to elaborate a CI vitrification method than to study ischemia. However, we will study ischemia, maybe, in the near future.

The things I would like to carry out are:

1. To elaborate a CI vitrification method for patients in a first approach. (I have already done a stable vitrification of an animal's brains. I will try to take pictures of vitrified sheep brains for the Immortalist.)

2. To perform some experiments with vitrification in Russia in order more to verify and improve it. I will write the Russian project for our discussion soon.

3. To try working out a method of cooling vitrified patients from -100ºC to -196ºC without cracking.

4. To study ischemia and a possible improvement of a preparation of patients to cryopreservation.

Yuri


LIFE EXTENSION NEWS

Shock sheet could be a lifesaver

For people who have just suffered a heart attack, "shock sheet," a device similar to an inflatable sleeping bag could prove to be a lifesaver.

Designed to be wrapped round a patient and inflated to raise upper body blood pressure within 30 seconds, the shock sheet helps squeeze blood out of the legs, which boosts blood flow to the heart and brain.

"This device buys you time. It's a cheap and simple way to save lives," New Scientist quoted its inventor, Mark Wilson, an anesthetist at East Surrey Hospital in Redhill, UK, as saying.

Shock sheet, which has so far increased blood pressure only in healthy volunteers, will soon undergo clinical trials.

Keeping the blood flowing to the brain is more important than supplying the limbs, says Desmond Sheridan, a cardiologist at London's St Mary's Hospital. The device should help shift blood flow away from the lower body.

According to Wilson, the shock sheet might also help doctors treat other conditions that cause blood pressure to fall, such as septic shock (systemic bacterial infection) and anaphylactic shock which is caused by massive allergic reactions. Yahoo! News

________________________________

Americans score low on hand hygiene

The survey was conducted by the American Society of Microbiology, an organization that has been urging people to wash their hands after using the toilet facilities. Generally, there was no improvement since the last survey, with one exception, Toronto. This is no doubt due to health officials urging the public for months to wash more frequently to help stop the spread of SARS.

"If this study had been pre-SARS, we would not have been different than any other city, but it is nice to look so squeaky clean," said Dr. Donald Low, microbiology chief at Toronto’s Mt. Sinai Hospital.

The survey was conducted at airport restrooms this past August in New York City, Chicago, San Francisco, Dallas, Miami and Toronto. The researchers pretended to brush their hair or put on makeup while watching and recording the public’s restroom habits.

Among the results:

Women are cleaner than men, 83% of women washed up compared to 74% of men.

For reasons no one could explain, women at the San Francisco airport had the worst record. Only 59% washed.

The dirtiest men were at Chicago’s O’Hare and New York’s Kennedy, where slightly more than 60% washed.

For effective disease intervention, the Society urges people to wash by rubbing their hands together with soap and warm running water. Adapted from FLORIDA TODAY

_________________________________

Another sweetener

In the last issue, in the Life Extension section, we wrote about a TIME article, comparing all the artificial sweeteners.

The bottom line was that based on current knowledge, Splenda is safe, Nutrasweet is probably safe, and questions remain about saccharin, the principal ingredient in Sweet N Low.

Now comes a report in WIRED about Tagatose. It’s a natural sugar. It looks tastes and cooks like sugar. It’s 92% as sweet as sugar but with only 38% of the calories. Research indicates it prevents weight gain, and doesn’t cause cavities. It’s safe for diabetics and may even help combat the disease. It’s expected to hit grocery shelves by the end of the year. All natural, it’ll be marketed under different brand names. It’s already in Pepsi’s Diet Slurpee. Kellogg’s obtained a patent in 2002 for use in one of their cereals. Wrigley and Kraft have patents of their own.

________________________________

Tomato a day keeps heart disease away

Eating one serving a day of tomato based foods such as pizza or other dishes with tomato sauce, could lower your risk of heart disease by as much as 30%. That’s the conclusion researchers at Harvard School of Public Health and Brigham and Women’s Hospital in Boston came to.

They found that people who consumed seven or more tomato based foods a week had a nearly 30% reduction in risk for cardiovascular disease, compared to those who ate less than 1 ½ servings a week. Adapted from FLORIDA TODAY

Boost your brain power

Do you sometimes feel as if your brain is on "empty?" Here’s some hints on keeping it in shape.

Use it or lose it. Research indicates that as you age you can reverse a decline in thinking abilities by becoming more mentally active. Learn a new language, study a new subject, play games like chess or Scrabble, work crossword puzzles.

Keep fit. Evidence shows that people in their 70s and 80s who stay healthy can expand their brain power, and easily match the mental abilities of a 30 year old.

More muscle builders: Read more…eat foods rich in brain boosting beta-carotene, (apricots, carrots, papayas, and sweet potatoes.)…use rhymes and acronyms to help remember facts and names.

Adapted from TopHealth


MEET DANILA MEDVEDEV

I’m 23 years old, and live with my parents in St. Petersburg, Russia In 1994 I graduated from physics and mathematics lyceum 239 (one of the best schools in Russia). While there I successfully participated in math and programming olimpiades (city and Russian) and debates. Programming Olympiads are contests in computer programming for secondary school and university students.

In 1996 I took the second place in the St. Petersburg contest and then, after about a month of intensive training, went to the All-Russian Olympiad (where I wasn't particularly successful, I must admit).

Then I entered International Management Institute (www.imisp.ru), one of the best private business schools in St. Petersburg and got a BBA there. Worked for 2 years in regional investment bank (www.trigoncapital.com). Currently I am working on my Ph.D. (in finance).

I was always interested in technology since I was a kid, but I could not really understand (reading mainstream popular science books written in the 70s and 80s) the potential of modern science then.

After connecting to the internet in mid-90s I quickly stumbled upon information about nanotech, transhumanism, cryonics, etc. and quite soon absorbed this new knowledge.

About 2 years ago I read The Prospect of Immortality and decided to translate it into Russian. It was done a year ago and if all goes well, it will be published in Russia (by the www.immortality.ru team). I also translated the Transhumanist FAQ into Russian

 (http://www.transhumanism.org/translations/russian/index.html)

which helped in increasing awareness about transhumanism here quite a bit.

It took some effort, but eventually I managed to persuade my family that my ideas about the future, transhumanism and cryonics are not stupid. Still, I could not make a strong long-lasting impression on them. They are no longer opposed to the idea of cryonic suspension, but they still won't do anything now to organize it.

Most of the friends I talked about cryonics with were somewhat interested, but they still don't see it as something realistic, something they should be seriously considering. However, I managed to convert one friend to scientific immortalism. It took about five hours of answering his questions about life, the Universe and everything on the night after his birthday, at a nearby lake.

There still aren't many cryonicists in Russia and there is no formal organization, but I've had occasional contacts with some Moscow-based cyonicists, who helped publish the translation of The Prospect of Immortality.

What free time I have, I like to spend it reading. I prefer popular science books and sci-fi, but I would read anything else, as long as it's well written and interesting. And since I feel comfortable reading a lot from computer screen, I also read everything I can find on the Net. Apart from that, I use the computer for whatever catches my fancy, right now - programming, film editing, etc.

It's probably easier for me to travel abroad than for many Americans. It only takes 3 hours by car to get to neighbouring Finland. So far I have been in Bulgaria (when I was a kid, during the Soviet time), in Switzerland (3 times, participating in the ISC-Symposium), in Japan (on a 3-week exchange program), in Finland (many times, including a one year of studies), in Sweden, in Estonia (at my company's HQ), in Latvia (on a business-trip) and in France (in Paris on a Corporate Away Day).

I still live with my parents. I don't want to get my own apartment here in St. Petersburg because as soon as I finish my Ph.D. studies here, I plan to move to some other country (most likely in Western Europe) where I can get a job in scientific research.

Best regards,

Danila Medvedev danila.medvedev@...

----

Today, through the accelerating pace of technological development and scientific understanding, we are entering a whole new stage in the history of the human species.

http://www.transhumanism.org/resources/faq.html


Small Print:

For more information about cryonics or Cryonics Institute and how to become a member, visit our web site at http://www.cryonics.org.

We encourage readers to forward issues to friends and interested parties. Please send any suggestions or comments to Long Life by emailing John@...

Long Life would like to thank Longevity Report, Wired News, InfoBeat, The New York Times, The New Scientist, Nanodot, Slashdot, contributors to the Extropian and CryoNet mailing lists, members of the Cryonics Institute, and others, for helping provide some of the free public information used in Long Life.

(Disclaimer: CI does not necessarily encourage or advocate the use of any products or practices mentioned in its newsletter.)


--
Sincerely, John de Rivaz: 
http://John.deRivaz.com for websites including Cryonics Europe, Longevity Report, The Venturists, Porthtowan, Alec Harley Reeves - inventor, Arthur Bowker - potter, de Rivaz genealogy,  Nomad .. and more

#27 From: "John de Rivaz" <John@...>
Date: Mon Nov 3, 2003 1:10 pm
Subject: Long Life 10
longevityrpt
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Long Life: the Cryonics Institute newsletter

November 2003 -- Volume 2, Number 9

Welcome to Long Life -- the electronic newsletter of the Cryonics Institute. We're here to update you with brief cutting-edge news, updates, links, and information about the latest scientific, medical, health, anti-ageing, and social developments relevant to CI's goal of saving, preserving, and extending human life. Long Life may also include news about Cryonics Institute events and member activities and opinion. We welcome your feedback, and encourage readers to forward issues to friends and interested parties.


 
CI and general cryonics news
 
CI Opens Discussion Group
 
An email  discussion group exclusive to CI members has opened. People who have paid for option one and option two membership have been invited to join, using the email addresses they have registered with CI. Anyone who has not been invited and who wants to join, is asked in the first instance to email john@... and when their email address is cleared with CI that they are a member they can be added to the list. Also if you didn't answer the original invitation it will now have expired, so again please email.
 
The group is moderated and it has already provided some useful discussion for members about finding local funeral directors, and it may result in changes in CI procedures in due course that will make it easier for people to make their arrangements. Do not feel that by joining it you will be bombarded with ceaseless cryonet type email you may prefer not to read.
 
Request For Help From Suspended Animation

October 31, 2003

A Letter from Ben Best, President of the Cryonics Institute:

Suspended Animation Incorporated is under serious attack in Florida from both the state Mortuary Board and from the city Zoning & Planning Commission. There will be a hearing next Thursday, November 6th, at 6pm which could be critical in determining the fate of SA.

Any cryonicists in the Florida area are urged to attend this meeting. Everyone attending who wants to speak will be allotted 5 minutes to give their views. Animal rights activists will probably be descending on the proceedings, despite the fact that SA will only be experimenting on rats and dead dogs (dogs already killed by the SPCA or similar organization).

Those not in the Florida area can help by sending messages to the city council members through their Internet links (below). Animal rights activists from all over have already been doing this. Below is the letter from the President of Suspended Animation requesting assist in his legal struggle. Please help if you can. This will affect the future of cryonics in a major way, I believe.

-- Ben Best



Dear Cryonics Enthusiast,

As the President of Suspended Animation, Inc. I am asking you to help us win a very important battle, a battle critical to cryonics in Florida as well as the entire cryonics community.

As you may know, we are a new cryonics company located in Boca Raton, FL. We began operations last year with funding support from the Life Extension Foundation. We have been instrumental in the cryosuspension of three Floridians and a similar number of cryonicists elsewhere in the country.

Our primary goal is to perform research that will enhance cryonics through whole body vitrification and vastly reduced previtrification ischemic damage. But, we also provide you the first response capability that may make the difference between a good resuscitation prognosis and oblivion.

SA is the only cryonics organization who plans to perform substantive research to improve both control of ischemia and reduction of cryosuspension damage. 95% of our efforts are directed to research to improve cryonics technology.

SA is the only company now providing professional Standby Based Transport to ensure you get immediate professional care from the moment of pronouncement.

Lastly, we are the only organization proposing to provide whole body vitrification. We welcome you to look over our website www.suspended.org and view how we are making a substantial impact on the industry and how we can be of service to Florida cryonicists.

We are in a crisis at this moment brought on by the pending refusal of Boca Raton to grant us occupancy and building permits and by the State Board of Funeral Directors and Embalmers who demand that we become a licensed mortuary. Unless we can reverse the Boca Raton licensing problem, an entire two year's worth of effort will be wasted as we are forced out of our facility and must seek another place from which to operate, if we can.

As I am sure you know, no cryonics organization has a lot of money to waste and this will come close to killing the entire operation. If we do not win in our battle with the State over becoming a licensed mortuary, cryonics will for all practical purposes be prohibited in Florida - yes I mean it - forbidden. Mortuaries are forbidden to treat patients except in the mortuary, thus all of the bedside anti-ischemia treatment vital to ensuring brain tissue viability is prohibited. This is only one roadblock created by the State's licensing requirement; there are many others.

We desperately need your help in two areas. First, there is a Boca Raton Planning and Zoning meeting on Thursday Nov 6 at 6:00 PM, in the Boca Raton City Hall that will debate our occupancy and building permits. The auditorium has 300 seats and to the extent they are filled with cryonicists, those in power can hear a voice for approving our permits. Furthermore, individuals can sign up to be heard for five minutes. If the seats are filled with animal rights activists and those who hate anything new or unknown, then only their voices will be heard as they have been so far.

We really need you. Unless there is a groundswell of support, they are going to recommend to City Council that our permits be denied purely because we are a cryonics organization.

In addition to your help at the meeting we would greatly appreciate it if you would send the attached letter (or one similar to it) to the Boca Raton City Council at the address below to encourage them to vote for us when the measure comes up. These guys all respond to the voters, and those who voice their preference are the only ones heard.

Boca Raton City Council
201 West Palmetto Park Road
Boca Raton, Florida 33432

Will you help? Please visit the following links below and send emails regarding the importance of the research that SA is conducting and how it is needed by the growing cryonics community in southern Florida.

Send an email to the Mayor of Boca Raton Steven Abrams from his web page

http://www.ci.boca-raton.fl.us/city/Mayor.cfm

Send an email to the Deputy Mayor of Boca Raton Susan Whelchel from her web page

http://www.ci.boca-raton.fl.us/city/Council1.cfm

Send an email to Council Member Susan Haynie from her web page

http://www.ci.boca-raton.fl.us/city/Council4.cfm

Send an email to Council Member David Freudenberg from his web page

http://www.ci.boca-raton.fl.us/city/Council3.cfm

Send an email to Council Member Bill Hager from his web page

http://www.ci.boca-raton.fl.us/city/Council2.cfm

Send an email to City Manager Leif Ahnell from his web page

http://www.ci.boca-raton.fl.us/city/message.cfm

At the following link http://www.suspended.org/counselletter.html you will find the letter attached to this document. Please send all your friends to our website and ask them to copy, paste and send the letter also. Have them send emails, make phone calls, anything that ensures SA is not stopped in furthering the very important research being done in cryonics. This is vitally important for all cryonics members independent of your membership organization.

We are fighting for our company and the right for cryonics to exist in Florida. This is a matter of life and death for us and you.

Sincerely,

David Shumaker


It is also quite a good idea to have individually worded letters from various people. This one written by me, John de Rivaz, is slanted for use by people outside the USA:
 
I am writing from England, having heard of the debate about the facility for Suspended Animation (SA) in your state. What you decide affects not just your own area but the whole world. Progress in medical technology affects many people in the present and the future. At one time solutions for things like plague, polio, heart disease and so on were considered impossible. It was only the actions of far sighted people that enabled what we now consider commonplace to be achieved.

I understand a pressure group is against the SA proposal. Such pressure groups often contain many people who have not thought the problem through, and a vociferous small number of people who enjoy imposing or supporting suffering and destruction from within the safety of a group. This is particularly irrational, and indeed offensive to many people, when the group claims to be against suffering.

It is also inappropriate in this instance, because SA are only proposing research on creatures which are dead anyway. They will be dead regardless of whether you permit SA’s facility or not.

When pressure groups are allowed to dictate public policy often enough, we end up with administrations such as were seen recently in Afghanistan and Iraq where authority was totally dysfunctional because it was driven by irrational beliefs, such as "If you die in battle defending your faith you go to heaven regardless of how bad you have been otherwise".

Denying the citizens of your state, and indeed the whole world, research that may extend their lives is little different to **permitting** life shortening medical experiments on **people**. Historians in the future may judge any political decision that denies life extending research just as harshly as other excesses of authority in the past. The research will be done somewhere but maybe much later in time, and if successful then it will be noticed that it could have been done before. Suppose, by way of example, some politicians had stopped research on polio in the past, and some maverick state had permitted someone to conduct it and found the solution in 1995. Think of the numbers of people that would have died or been crippled in the meantime. Then consider how historians would have looked back on the personalities and motives of the politicians who denied it previously. How would their descendants be treated by their contemporaries? They could not take comfort in the fact that at the time most people thought success for the research to be impossible. This is often the case for any research - that is the nature of research.

Do you want to take this risk?


 
The Life Extension Foundation are sending this to their members:
 
Science under Siege
 
Dear Life Extension Member,

Never before have so many bureaucrats stood in the way of medical progress.

Embryonic stem cell research, for instance, is fundamental to the most promising advances in regenerative medicine. The problem is that government bureaucrats are blocking stem cell research that could lead to advanced treatments for Parkinson's disease, heart disease, bone damage, nerve damage, burns, liver damage and Crohn's disease. The U.S. government has clearly shown that they do not care how much suffering they are causing through their repressive policies. Without citizen activism and opposition, we can all expect to live shorter, more painful lives, as arrogant government legislators and regulators suppress promising research.

According to Reason magazine, if embryonic stem cell research and therapeutic cloning are banned, you, personally, will one day likely die from a disease that could have been curable. Today, 150,000 people will die worldwide, mostly from diseases and conditions that would be curable without these attacks on medical research. Are you going to let that go, or are you going to stand up and fight the politicians who are trying to stop progress?

Life Extension Breakthrough Crippled

By Government Interference

As most Life Extension members know, the FDA is censoring validated scientific data about nutrients, hormone and drugs that can prevent disease and possibly slow ageing. The consequences of the FDA’s unconstitutional actions are that Americans are dying from medical ignorance, as published studies clearly show that most of today’s lethal diseases can be better prevented and treated.

One of the most effective methods of extending lifespan is reducing the excess secretion of insulin. Humans and animals undergoing caloric restriction experience a 42% decline in blood insulin levels. Many scientists attribute the longevity benefits of caloric restriction at least in part to this dramatic drop in excess insulin levels.

Life Extension has developed a patent-pending supplement that lowers fasting insulin levels. Fire Marshals in the City of Sunrise, however, have closed down the lab extracting this supplement out of avocados. We don’t know if this lab will ever open again, since the Sunrise bureaucrats have stonewalled attempts to show that the lab is compliant with their regulations.

Boca Raton Zoning Officials

Seek To Evict Cryonics Company

Suspended Animation, Inc. is a company seeking permission from the City of Boca Raton to conduct research aimed at protecting neurons from ischemia (reduced blood flow) and further develop a process known as vitrification (low temperature preservation without cellular damage).

After a large amount of research dollars had been expended in setting up this facility, the city of Boca Raton decided to deny an occupation license to this company. The good news is that Suspended Animation’s attorneys have clearly demonstrated that these research activities are permissible. There is a risk, however, that the City Council could arbitrarily deny the issuance of a license to operate based on political considerations.

Suspended Animation’s fate will be determined Thursday, November 6, at the Boca Raton City Council Meeting. This meeting begins at 6:00 PM.

I am asking South Florida Life Extension members to show public support for establishing this world-class research facility by attending the Boca Raton Planning and Zoning meeting that will be will be held in the city hall located at 210 West Palmetto Park Road (a few miles East of I-95 on the North side of Palmetto Park Road). The auditorium has 300 seats and to the extent they are filled with supporters of science, those city council members can hear a voice for approving Suspended Animation’s permits.

The scientists at Suspending Animation, Inc. have diligently worked on this project for the past 18 months, only to be threatened with eviction because of arbitrary and capricious actions taken by bureaucrats who have no idea of the potential significance of this research (i.e. more organs available for transplant, less brain damage occurring from trauma-surgery, and possibly the perfection of whole body vitrification).

It would be a travesty to see this opportunity lost because we failed to let our voices be heard. I urge each and every one of you to attend this meeting at Boca Raton City Hall (210 West Palmetto Park Road) this Thursday (November 6) at 6:00 PM.

I suggest that everyone planning on attending this meeting call Dayna Dye (954-202-7716) on Thursday to make sure that Suspended Animation’s case will be heard that night. There have been bureaucratic delays, but we are fairly certain that Suspended Animation will be the prominent issue on the November 6 Boca meeting agenda.

How Bureaucrats Have Become Unaccountable

Every day, various government agencies hold public hearings where citizens have open access to important decision-making processes. Regrettably, the citizenry has become apathetic and has given virtual free reign to government to make arbitrary edicts that adversely affect our finances and our health.

Our remarkable government of "We The People" has been replaced by "They the Unaccountable." We have grown accustomed to bureaucratic intimidation rather than taking the initiative to reign in inappropriate government actions.

In this instance, a few employees of the zoning department of Boca Raton could sabotage a private scientific endeavor that could lead to marvelous medical advances.

This country was founded by concerned citizens who took the time to attend assemblies that enabled common sense courses of political action to be taken. In today’ world, citizens sit at home in front of television sets and watch the adverse affects of incompetent governmental actions unfold before their very eyes.

I can tell you personally that there is nothing more exhilarating than taking on an arrogant bureaucracy and winning. For the past 20 years, we have challenged the authorities on constitutional, scientific and ethical grounds and have consistently prevailed. Our victories have occurred only because our supporters have risen to the occasion and let officials know that inappropriate governmental actions will not be tolerated.

Please join us at the Boca Raton City Hall (210 West Palmetto Park Road) on Thursday, November 6 at 6:00 PM. We cannot let a local zoning department deny medical progress that could benefit all of mankind.

I will personally look forward to meeting you this Thursday night at the Boca Raton City Hall, which is less than a 15- minute drive from most of your homes.

Furthermore, individuals can sign up to be heard for five minutes. If the seats are filled with animal rights activists and those who hate anything new or unknown, then only their voices will be heard as they have been so far. We really need you. Unless there is a groundswell of support, they are going to recommend to City Council that our permits be denied purely because we are a cryonics organization.

Suspended Animation, Inc. has made vast technical improvements to the cryo-preservation process and has greatly enhanced the quality of standby technical service delivered to the cryonics' patient. Suspended Animation will be the only organization in the world offering whole body vitrification. If Suspended Animation, Inc. is prohibited from operating in South Florida, then all of this means little to us living here.

If you have any questions about the most important issue to ever face Florida cryonics members, please call me at 954-494-3212.

For longer life,

William Faloon

[ David Shumaker letter as above appears here ]

P.S.- The FDA recently blocked a new stem cell therapy for heart damage that has proven very successful in trials. The therapy uses stem cells from the patient's own blood, directly analogous to using your own blood for transfusions in surgery. This sort of overzealous reaching on the part of the FDA carries a staggering cost; 50,000 lives every year are lost waiting for heart transplants or a working therapy for heart disease. We must protest this sort of FDA interference if we are to benefit from advanced medical technologies currently in development!

Message #22752
From: "Reason" <reason@...>
Subject: attacks on therapeutic cloning damaging medical progress, shortening lives
Date: Thu, 30 Oct 2003 14:08:50 -0800

The attacks on therapeutic cloning are causing great damage to medical
progress in this field:

http://www.azdailysun.com/non_sec/nav_includes/story.cfm?storyID=75791
"President Bush's current limitations on stem cell research and a bill that
would place criminal penalties on scientists who use a particular cloning
process are causing biotechnology corporations to fall apart or flee to
other countries, according to a stem cell scientist."

http://story.news.yahoo.com/news?tmpl=story&cid=534&e=3&u=/ap/20031027/ap_on
_sc/stem_cell_research
"if embryonic stem cell research had not been involved in politics we would
be far ahead of where we are today."


Please use the following links to see how you can help to make your voice
heard. I urge you to contact your elected representatives and tell them that
what they are doing (or allowing to happen) is immoral and wrong. Hundreds
of millions of people are suffering and dying today, now, from conditions
that could soon be cured, or might already be curable, if not for these
attacks on therapeutic cloning and stem cell research.

A total ban on therapeutic cloning in the US is still pending:

http://www.longevitymeme.org/projects/oppose_the_theraputic_cloning_ban.cfm

The European Parliament is still looking at banning all stem cell research:

http://www.longevitymeme.org/projects/oppose_the_european_stem_cell_ban.cfm

More information on the UN global ban on therapeutic cloning is here:

http://www.longevitymeme.org/projects/oppose_global_theraputic_cloning_ban.c
fm

The FDA has blocked a working therapy for heart disease that could save an
estimated 50,000 lives worldwide every day:

http://www.longevitymeme.org/projects/protest_fda_interference.cfm


Reason
Founder, Longevity Meme
reason@...
http://www.longevitymeme.org

> -----Original Message-----
> From: wta-politics-admin@...
> [mailto:wta-politics-admin@...]On Behalf Of Hughes, James
> Sent: Thursday, October 30, 2003 12:40 PM
> To: wta-politics@...
> Subject: [wta-politics] Move to ban human cloning likely to divide UN
>
>
>
>
http://news.ft.com/servlet/ContentServer?pagename=FT.com/StoryFT/FullStory&c
=StoryFT&cid=1066565433416
>
> Move to ban human cloning likely to divide UN
>
> By Mark Turner at the United Nations and Clive Cookson in London
>
> Published: October 28 2003 17:30 | Last Updated: October 28 2003 17:30
>
>
> The US and the UK, normally stalwart allies on the international stage,
> may be heading for a face-off at the United Nations over moves towards
> an international convention banning all forms of human cloning.
>
> Diplomats said a decision was expected this week or early next week on
> whether to press for a vote in the UN General Assembly. Costa Rica, the
> US and almost 60 other countries have sponsored a resolution calling for
> a convention against human cloning to be prepared by next year. In the
> meantime, it says states should prohibit the research, development or
> application of "any technique aimed at human cloning".

----------------------------------------------------------------------

[ end of Life Extension Foundation document ]

 
General News Items

Important Note: A lot of these items are from sources designed for public consumption and contain no references or further information. It is up to readers to do their own web searches or whatever for further information.

New alternative to "slash, burn or poison" cancer treatment
 
CANCER patients will be injected with their own blood cells, newly armed with a cancer-fighting gene, in a world-first treatment created in Melbourne. more on
 

Medical system is leading cause of death and injury in US

Shocking statistical evidence is cited by Gary Null PhD, Caroly Dean MD ND, Martin Feldman MD, Debora Rasio MD and Dorothy Smith PhD in their recent paper Death by Medicine - October 2003, released by the Nutrition Institute of America.

"A definitive review and close reading of medical peer-review journals, and government health statistics shows that American medicine frequently causes more harm than good. The number of people having in-hospital, adverse drug reactions (ADR) to prescribed medicine is 2.2 million. Dr. Richard Besser, of the CDC, in 1995, said the number of unnecessary antibiotics prescribed annually for viral infections was 20 million. Dr. Besser, in 2003, now refers to tens of millions of unnecessary antibiotics. The number of unnecessary medical and surgical procedures performed annually is 7.5 million. The number of people exposed to unnecessary hospitalization annually is 8.9 million. The total number of iatrogenic deaths shown in the following table is 783,936. It is evident that the American medical system is the leading cause of death and injury in the United States. The 2001 heart disease annual death rate is 699,697; the annual cancer death rate, 553,251.

more on:
 
 

High-Tech Daydreamers Investing in Immortality

By JAMES GORMAN

Published: November 1, 2003

CAMDEN, Me. — Aubrey de Grey took the stage of the Camden Opera House, tugging at a beard worthy of Methuselah, to tell his listeners that they could triumph over death.

Mr. de Grey was not selling an afterlife or a metaphor. He is a geneticist at the University of Cambridge, in England, and his prophecy was straightforward if hard to believe: Getting old and dying are engineering problems. Ageing can be reversed and death defeated. People already alive will live a thousand years or longer.

Advertisement

He was at pains to argue that what he calls "negligible senescence," and what the average person would call living forever, is inevitable. His proposed war on ageing, he said, is intended to make it happen sooner and make it happen right. He subscribes, it seems, to the philosophy articulated by Woody Allen: "I don't want to achieve immortality through my work. I want to achieve it through not dying."

This notion of getting in on the ground floor of immortality was apparently appealing to the roughly 500 people who came in mid-October to this coastal town of big yachts and small gift shops about 70 miles northeast of Portland to attend Pop!Tech, an annual technology conference. They were ready for the Next Big Thing. After all, many of them were present at the creation of the last one, the spread of the personal computer and the explosive growth of the Internet.

Stephen M. Case, the founder of AOL, was here, as were John Scully and Robert Metcalfe, who started the conference seven years ago. Mr. Scully was the chief executive of Apple, after he had left PepsiCo. Mr. Metcalfe invented the Ethernet and founded 3Com, among a few other achievements, before he became a venture capitalist. Other, lesser known entrepreneurs and investors, along with dot-com veterans, a gaggle of journalists and the merely curious, also attended to look for new ideas or promote them, and to use the gathering of thinkers and talkers as a guide to what's next.

The answer was clear. Now that the giddiness and glamour of the killer app and ultimate hand-held gizmo have passed into memory, it is biology that beckons. The possibility of making money out of biotech is of obvious interest. But the more exciting question in the air was not so much where to put your money as what to think about. Differentiating between vision and fantasy would come next.

Many in the audience seemed unafraid of amending the presumed laws of nature. When Juan Enriquez, from the Harvard Business School, displayed an X-ray of a chicken with three wings and asked who believed that this sort of research ought to continue, about two-thirds of those in the audience raised their hands. This was before they knew its purpose, which is to understand how to regenerate damaged tissues for human beings.

Mr. Enriquez said he was surprised, as well he might be. It is not often you find 300 people ready to vote for extra limbs, no matter the reason.

Other speakers addressed the importance of stem cell research, ocean exploration, a crisis in the patent system, the soul-deadening effect of suburbs, and the mode by which the Earth will die.

For audacity of imagination, though, Mr. de Grey was matched only by Joe Davis, a molecular artist from M.I.T. with a peg leg and a devilish glint in his eye, who, with the help of scientists at Harvard and M.I.T. has made art of DNA by inserting coded messages into the genes of bacteria. He does not work only with DNA. He also pointed out that drawings sent into space, presumably for curious extraterrestrials, lacked anatomically correct female genitalia. He has not been able to remedy that, but he did record vaginal contractions and translate them into a radio broadcast.

He also provided instruction in basic biology using a DNA model made of garden hose to great effect. All in all it was a perfect atmosphere for Mr. de Grey, whose campaign against death has something of the feeling of an Internet start-up. On one hand he is promising the world. On the other, the underlying science and technology are real, Mr. de Grey argued. And the business plan is, if nothing else, bold.

Yet without true expertise in some very sophisticated biology, it was hard to know how far away from the mainstream he was.

Mr. de Grey is probably several steps ahead of the avant garde in his conviction that the 4,000- or 5,000-year life is right around the corner. But extending the average human life to 150 years is commonly discussed. And some gerontologists say there is no theoretical limit to the human life span.

Mr. de Grey's ideas were not completely new to people who have been pondering cyborgs and artificial intelligence for years. "I think, and I've thought this for a long time, that we live, roughly speaking, in the last generation of human beings," said Whitfield Diffie, chief of security for Sun Microsystems, a pioneer in encryption, and a freewheeling thinker often sought after for such conferences as a speaker. He was just visiting this year and said he was fascinated by the grand claims for the biological century, which he views as probably too conservative.

He is convinced, he said, that there are probably people alive already today who will have unlimited life spans. And he was unimpressed by the scepticism of more conservative experts in the field of ageing. After all, he said, he had witnessed change coming rapidly from unexpected directions in the digital world.

Mark Hurst, who runs a consulting company in New York and founded a Web site for consumer complaints, thisisbroken.com, said after the meeting that he was "sceptical and entertained." But, he said, "as far as actually believing it," he thinks most of those he talked to at Pop!Tech had the same question about the scientific details as he did, "What the heck was he talking about?"

Mr. de Grey compared the cellular and molecular damage that ageing causes to what happens to a house. Houses keep going, he said, not because they are built to be immortal, but because people keep repairing them. Science should take the same approach to the human body, he argued; many, if not all, of the techniques for making such repairs are already available.

He also had an answer for how to pay for the necessary research. First prove that the life of laboratory mice can be extended. Once people realize that ageing can be reversed in a mammal, he said, research will take off, and the demand for extending life far beyond the current limits will be universal. Then people can just keep repairing themselves and researching new ways to take care of future damage.

To get this whole process going, Mr. de Grey established the Methuselah Mouse Prize in September. The prize is drawn from a fund, at methuselahmouse.org, now open for donations. A portion of it is to be offered each time the record is broken for prolonging mouse life. A portion will also be offered for reversing ageing, which is a more complicated calculation. The prize fund stands at $28,448.

With enough money, Mr. de Grey said, it would take about 10 years to find a proven method for taking any 2-year-old mouse, already two-thirds of the way through a normal life, and extending it to five years, the equivalent of 150 years for humans. At that point the war on human ageing could begin in earnest.

Mr. de Grey described himself as a theoretician, and as such he holds a position that is rejected by most researchers into the science of ageing. For instance, Leonard P. Guarente, a professor of biology at the Massachusetts Institute of Technology, said, "The idea of people living to a thousand is preposterous." There are mechanisms that may well allow extending life, he said, but so much goes wrong as organisms deteriorate with age that "trying to fix everything that's going wrong is impossible."

Mr. de Grey is undeterred by criticism and relatively unconcerned about suggestions that near-immortality, if achievable, might not be entirely a good thing. Asked what would happen to reproduction when the living started to accumulate the way the dead do now, taking up all the space, he said they would no doubt resent new arrivals. He said matter-of-factly that it would be, by and large, a world without children.

He recognized that there would be difficult issues to face but brushed aside any suggestion that defeating death was not a fundamentally good thing to do.

"Ageing really is barbaric," he said. "It shouldn't be allowed. I don't need an ethical argument. I don't need any argument. It's visceral. To let people die is bad."

Although Mr. de Grey got his listeners talking and thinking, there was no indication that their interest meant they had signed on to the program. Mr. Diffie, for one, was unconvinced by the notion of death as something that arrived by accident in evolution. It was, after all, universal. "My nose for when I don't understand something tells me there's something here I don't understand," he said. " I don't think they understand it either."

The audience was not lacking in millionaires, but there was no great surge of donations to the Methuselah Mouse Prize after Mr. de Grey's talk. According to his online record of donations, $1,849 was received during or after Pop!Tech, which ran from Oct. 16 to 18.

Mr. de Grey has no illusions about the challenge he faces. He wants to establish an institute to direct research, he said, adding that he probably needs $500 million to achieve the goal of using mouse research to kick-start a global research explosion on human ageing. That includes the prize fund.

Just before a dinner the night after his talk, one of the participants in the conference approached him and asked, "Can we talk about funding?"

"Yeah," Mr. de Grey said, "how much money do you have?"


Small Print:

For more information about cryonics or Cryonics Institute and how to become a member, visit our web site at http://www.cryonics.org.

We encourage readers to forward issues to friends and interested parties. Please send any suggestions or comments to Long Life by emailing John@...

Long Life would like to thank Longevity Report, Wired News, InfoBeat, The New York Times, The New Scientist, Nanodot, Slashdot, contributors to the Extropian and CryoNet mailing lists, members of the Cryonics Institute, and others, for helping provide some of the free public information used in Long Life.

(Disclaimer: CI does not necessarily encourage or advocate the use of any products or practices mentioned in its newsletter.)

--
Sincerely, John de Rivaz: 
http://John.deRivaz.com for websites including Cryonics Europe, Longevity Report, The Venturists, Porthtowan, Alec Harley Reeves - inventor, Arthur Bowker - potter, de Rivaz genealogy,  Nomad .. and more

#26 From: "John de Rivaz" <John@...>
Date: Sat Oct 18, 2003 10:15 am
Subject: Long Life 9 - Immortalist Highlights
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Long Life: the Cryonics Institute newsletter

October 2003 -- Volume 2, Number 9 - Immortalist Highlights

Welcome to Long Life -- the electronic newsletter of the Cryonics Institute. We're here to update you with brief cutting-edge news, updates, links, and information about the latest scientific, medical, health, anti-ageing, and social developments relevant to CI's goal of saving, preserving, and extending human life. Long Life may also include news about Cryonics Institute events and member activities and opinion. We welcome your feedback, and encourage readers to forward issues to friends and interested parties.

There are separate issues for highlights from the latest issue of The Immortalist. The reason for this is that otherwise the file is too long for some readers, and also the publication dates of The Immortalist are not synchronous with the start of each month.
 
I would also urge readers to subscribe to the paper issue of The Immortalist (see http://www.cryonics.org/info.html ) as not everything is reproduced in this email version.
 

 
From the Immortalist: 
 

News & Views Canadian, Russian and Australian News

Research Report Yuri Needs More Subjects

Cryonics Europe Report Chrissie Misses us!

Annual Meeting Photos (not in this e-email edition)

World Wide Cryonics Support List It’s Growing

NanoGirl News Gina Has The Latest! (not in this e-mail edition - it is in CryoNet)

Meet Alan Sinclair New CI Director!

An Australian Conversation: Two Aussies Chat

Life Extension News: All About Honey The Holy Grail?

Letters - We Received Two!!

CI’s New President

Editor’s Corner (not in email edition)

A Look Back A Youthful David Ettinger (not in email edition)


 
News and Views
 
PASSING THE TORCH
 
At the Cryonics Institute's Annual meeting  held on September 28, Robert Ettinger congratulates Ben Best on his election as President of the Cryonics Institute. Ben is only the second president CI has had in its 27 year history. To insure continuity, Robert Ettinger has agreed to accept the position of Vice President.
 
Royse Brown continues as Secretary. Joe Kowalsky is now Assistant Secretary, and Pat Heller remains Treasurer. There were four Directors up for re-election, Bob and Connie Ettinger, Pat Heller, and Jack Nixon. All were reelected except Jack Nixon. Jack  graciously relinquished his directorship so  that Alan Sinclair could be elected to the Board.
 
This was a measure of gratitude for the effort Alan has put into making the UK group a success.  In Immortalist Society business, York Porter was elected President, Robert Ettinger, Vice President, John Besancon and Royse Brown retain their respective positions-Treasurer-Secretary.
 
In a closed door session, David Ettinger reported to the Board on the status of negotiations with the State of Michigan which claims CI is operating as an unregulated funeral home and cemetery.

After the meeting, he  issued  this statement.
 
"The State of Michigan Department of Consumer and Industry Services has issued orders limiting CI's activities pending its licensure as a cemetery, which the Department claims is required. CI  has filed papers indicating that it disagrees, and stating that the orders (which were not issued by a court) have no effect, because the Department has no jurisdiction over CI. Moreover, the orders have no impact on CI's patient care.
 
CI cannot be more specific regarding the resolution of these matters at this time, because of the sensitive nature of the legal process."
 
"However, CI is hopeful that matters will soon be resolved favorably. The State of Michigan has made clear in its press release that it is not anti-cryonics and believes that CI could continue to operate successfully   if licensed as a  cemetery."
 
TIME SHIP --- SAFETY AND YET VISIBILITY  - NOW YOU CAN HAVE IT ALL!
 
A while ago some cryonicists wanted to build a cryonics storage building called the "Time Ship."  I had suggested it be built in Arizona near where VentureVille is going to be built.   The reasons for that are that this is the safest place in the USA for the long term storage of frozen people.  Less earthquakes, tornadoes, unrest, blizzards, etc.
 
When I discussed Arizona with Mr. Valentine, the proposed TimeShip architect, at the conference at Asilomar, he seemed to want to build it in an area where a  lot of people would come and see the beautiful building and not in rural Arizona.  Someone said he would prefer a place near Disney World in Florida.  Of course Florida would be a very dangerous place to store frozen people. 
 
But now something has happened to make central Arizona possibly the best place overall.  There are rumours that Six Flags is going to build a giant Disneyland type place six miles from here on the I-17.  If this is true, this will make that location, perhaps, the most visited place in the United States.
 
First of all, its already one of the most travelled because the I-17 connects the I-40 to the I-10.  Then its half way between Phoenix and Sedona, Flagstaff, Prescott and Payson.  So most of Phoenix travels past the spot once or more each summer.  Then Arizona has a lot of tourists from all over the world each year. 
 
And the site is not far from the Grand Canyon, Painted Desert, Petrified Forest, and Meteor Crater.
 
It is predicted that if Six Flags goes in, this will be the most visited place in the nation. And yet, one can buy a 40 or 80 (or larger) acre of land a few miles from this for peanuts (that won't last much longer when the word gets out).  But right now you can buy 80 acres for a whole lot less than one acre near Disneyworld Florida.
 
Imagine having an 80 acre campus with storage for the TimeShip in an area where  many millions of people from all over the world could drive by it each year and yet it could still be kept secure because of the large piece of land it sits on.
 
Does anyone know how to notify Mr. Valentine?
 
David Pizer
SUSPENDED ANIMATION ANNOUNCES NATIONWIDE  PREMIUM STANDBY
TRANSPORT SERVICE
 
Suspended Animation, Inc. has announced that effective immediately it is available to provide advanced professional Standby Based Transport (SBT) to cryonicists signed up with ACS, Alcor or CI from anywhere in the United States.
 
Ischemic damage is a major threat to patient resuscitation since it may endanger the very fabric of memory in the brain. Irrespective of the amount of cryopreservation damage done to the patient, if ischemia has already destroyed memory before the patient is cryopreserved, there may be little nano-technology or other future medicine can do to recover it. The goal of SA's SBT is to deliver into the cryosuspension process a patient whose total unmitigated normothermic ischemia time has been held to only a few minutes, and whose overall unmitigated pre-suspension cold ischemia time has been kept to only a few hours.
 
SA uses a paid professional SBT team consisting of a Ph.D. Cellular Pharmacologist; a surgically skilled Paramedic; a team leader with experience on numerous standby, transport, and recovery activities; and other experienced personnel. All team members have actual recent transport experience and have trained together as a unit.
 
The team is dispatched from SA's headquarters in Boca Raton, FL by aircraft or local transportation as appropriate and remains with the patient until needed or the crisis is otherwise resolved.
 
With the team comes SA's air transportable patient support system, the most advanced and complete patient treatment system in the cryonics community. The system consists of SA's portable ice bath; with respiration integrated thumper for optimum cardio-pulmonary support; an advanced anti-ischemia and blood stabilizing pharmacological package; SA's bypass washout, cool down and perfusion system with its integrated temperature, pressure, and flow monitoring equipment and a heat exchanger/ ECMO for cooling and oxygenating blood and washout fluid; a large volume of MHP washout fluid and where appropriate glycerol based cryoprotectant; plus surgical and support kits for all contingencies.
 
The team acts immediately upon patient pronouncement to administer anti-ischemia medications, apply cardio-pulmonary support (CPS) and initiate external cooling. Normally, medication and CPS are initiated within seconds of pronouncement with cooling beginning within a couple of minutes. 
 
The patient is then quickly transferred to the closest local site suitable for surgery to initiate blood washout with oxygenated and chilled MHP washout fluid, followed by further closed cycle oxygenated cooldown.
 
Once the patient is washed out and cooled to just above freezing, they are either transported by air ambulance for vitrification or freezing or are immediately perfused with glycerol for dry ice freezing on the way to a custodial facility. In any case, beginning seconds after death the patient is medicated, kept oxygenated, is cooled to just above freezing, may or may not be cryoprotected, and is transported by air ambulance. (Note that this is a nominal description of the process and each case may vary to some degree from the norm.)  that SA does not store cryonics patients and persons contemplating using SA for SBT must contract with Alcor or CI (or via ACS with one of the above companies) for long term custodial care.
 
SA believes ischemic time is the greatest single enemy of successful cryopreservation and professional SBT is the best current means of mitigating it.
 
CI AND THE BLACKOUT
 
Mark Plus asks whether the power outage that included much of Michigan could  affect Cryonics Institute's operations, and in particular our liquid nitrogen  supply.
 
Obviously a protracted and broad-based power failure could affect just about  everything, anywhere. A brief or local power failure, however, is only a minor  nuisance.
 
As to liquid nitrogen, CI has a 3,000 gallon bulk storage tank. If caught half full at time of loss of capability of new deliveries (and we don't let it get lower than this), then the supply would last about three weeks. Meanwhile,  of course, we would be looking for outside sources of emergency supply if  necessary.
 
As for the electricity for general purposes at the facility, we have a gasoline generator for emergencies. The alarm system has battery backup, as well as  wireless. We have land line phones and cell phones.
 
Closing of airports can obviously be a problem, and this can happen just from a snow fall. Again, there is usually something that can be done at some price, but there is an unavoidable degree of risk. Risks can always be reduced if you are willing to pay in money or/and inconvenience; it's always a trade-off, and never perfect.
 
The outage in Clinton Township lasted about 30 hours--worst ever here.
 
Robert Ettinger
Cryonics Institute
 
CSC BBQ A SUCCESS!
 
Despite the blackout of my condo the day before, the Toronto cryo-BBQ was a great success, with 18 attendees socializing on a beautiful day.
 
After, Christine Gaspar (President of the Cryonics Society of Canada) led a discussion on cryonics in Canada.  Then Ben Best gave an excellent and very relevant talk on ageing and dementia.  Ben has researched this area extensively, and written on it - see, for example,
http://www.benbest.com/lifeext/Alzheimer.html .
 
The Toronto local response group had a short meeting prior to the BBQ.
 
I led a discussion on the use of a Power of Attorney for Personal Care.  I circulated a draft, based on a typical Power used in Toronto, but substantially modified to make clear that its purpose was to maximize a successful cryopreservation.  For example, it provided that the person's intent is to be kept alive, including by artificial life support, until otherwise directed by a cryonics team- unless significant brain damage would result.
 
There are difficulties in clearly defining this, and a number of excellent suggestions were made.  In addition, Christine advised that the Power should make it's "do keep alive" very clear, such as by using large, bold font, because the norm is that Powers state the opposite.  Christine and I will prepare a new draft and circulate to the group. The group had a good discussion about equipment needs. Christine will chair future meetings of the group, and Brent Erskine will act as secretary. On a personal note, my wife and I will be moving to Sarasota, Florida at the beginning of October- but will return to Toronto on a fairly frequent basis.
 
Bruce Waugh
----------------------------------------------
The article that Bruce cited about Alzheimer's Disease is a new one on my website. However the bulk of my talk was concerned with Mechanisms of  Ageing. For those who have read my webpage on this subject before, I would recommend a second look  because I greatly revised and re-wrote much of it in preparation for the presentation I gave at Bruce's Summer Party:
 
Bruce has given Summer Parties every year in  Toronto for well over a decade. Toronto has an exceptional number of cryonics activists and an exceptional level of organization of those activists. 
 
This is remarkable considering that Toronto is not in the United States and when comparisons are  made with major cities that are in the United States.
 
I believe that Bruce's parties have had a great deal to  do with our success. Although he is now becoming a "snow bird" in his move to Florida, he has told us that he intends to continue holding Toronto Summer Parties.  Thank you Bruce !!
 
Ben Best
 
====================

CRYONICS ASSOCIATION of AUSTRALIA
 
Theo Tatton CAA's Executive Officer advises us that the CAA has a bulletin board: caa-list@... Other officers are: Terry Ward, Finance Officer and Assistant Executive Officer, Joseph Allen, Service Coordinator and Phillip Rhodes, Public Relations Officer  It's mailing address and phone number is: P.O. Box 57, Hampton  Vic. 3188 Australia. Phone 61-3-9589-6236
 
This information will be carried permanently on our Directory of CI Worldwide Support Groups.
_______________________________
ALCOR PRESIDENT RESIGNS
 
This was reported in Alcor's September  e-newsletter: "On August 10th 2003 Jerry B. Lemler MD tendered to the Alcor Board of Directors his intention to resign as the foundation's CEO at the expiration of his current yearly agreement, on December 31st of this year. The Board has accepted Dr. Lemler's resignation."
___________________________
WORLDS FIRST CLONED CAT.
James Clement sent us this report adapted from MSNBC: Appropriately named cc (for carbon copy,) the feline was born December 22, 2001 at Texas A&M College of Veterinary Medicine. "Cc's a sweet pet," according to Duane Kramer, a professor at A&M, and a member of the cat cloning team.  He continued, "At A&M we try to enrich the lives of all our research animals with attention, interactive toys and good adoptive homes.
 
In keeping with this commitment to normalcy, cc will be allowed to breed and have a litter. Researchers are eager to know what a cloned kittens will be like.  So far no mate has been selected and no date has been selected. The staff want to be sure the moment is right because cc is a landmark achievement in veterinary science.
 
Though tests prove the cat is a genetic match to the DNA donor, Rainbow, cc has her own traits, markings, personality and colouring.
 
Her incredible journey began with a  nuclear transfer - a cell nucleus from Rainbow's ovarian tissue was inserted into another cat's egg cell where the nucleus had been removed. The resulting embryo was implanted into Allie, the surrogate mother feline.
 
Ultrasound confirmed pregnancy a little later, and cc was born by C-section 66 days later.
 
A&M scientists point out that it took more than 80 tries to get cc, who is not only the first cat clone, but also the world's first companion animal cloned.
 
Most people felt a canine would be the first pet clone. A wealthy California businessman set aside millions to replicate his mixed breed dog, Missy. But researchers found out that canine cells were more difficult to deal with than feline cells.
 
Researchers went on to say  that the problems that have plagued some cloned animals seem to have bypassed cc.

There's no sign of accelerated ageing, which was a problem with Dolly the sheep. There's been no obesity, which has been a concern in some strains of mouse clones, and there are no disfigurations or abnormalities.
________________________________
RUSSIAN UPDATE
 
Danila Medvedev  sent us some Russian news. (We'll carry his bio in the next issue)
 
1) As you may already know, my translation of Ettinger's The Prospect of  Immortality was recently published in Russia. If you have any questions regarding the publication, you can probably ask Igor Artyuhov (artyuhov@...).
 
2) This one is semi-serious, but anyway:
Russian biologist Sergey Bodrov declared a small territory in Antarctica an independent state. The name of the new country is "Immortia" meaning "land of immortals". Bodrov found out that some
unclaimed territories near the South Pole and claimed them in accordance with  international law.
 
Sergey Bodrov proclaimed himself a Prince of Immortia and has already developed the Declaration of Independence and the Constitution of Immortia. The main principle of the Constitution is life extension by any means possible, including cloning.
 
This has been covered by some newspapers and Russian TV.
 
The original news item from NTV:(In Russian with Robert Ettinger's photo.)
http://www.ntv.ru/news/index.jsp?nid=26956
 
Home page of Immortia, in English
< http://www.angelfire.com/fl5/immortia/1024X768/indexe.html >
________________________________
 
CORNWALL MEETING OF CRYONICS EUROPE HELD ON SEPTEMBER 6TH AND 7TH.
Around twenty people attended during the weekend. Among the more frequent members, we were very pleased to welcome several new faces. Some were hoping to become members and ultimately, suspension members, while others were here to find out more or to support partners with an interest. We were also pleased to welcome Richard, a funeral director from the West Country, who may be interested in becoming a part of Cryonics Europe in both a personal and professional capacity.
 
Though largely billed as a social event, when a group of committed cryonicists get together, discussion becomes centred on the possibilities, problems and solutions. It was a lively gathering and we hope informative for all concerned.
 
With potential new members, there was an opportunity to answer many questions and hopefully to encourage and inform. The weather was fantastic so the meeting took place outside and allowed plenty of chance for us all to mix and chat informally. Saturday concluded with a barbecue, much to the delight of our two dogs who made the most of any dropped tidbits!
 
Many thanks to everyone who made the long journey and we look forward to future gatherings and welcoming greater interest in joining the select band of cryonicists.
 
Chrissie de Rivaz, Chairman Cryonics Europe

RESEARCH REPORT
 
Sep. 28, 2003
 
By Dr. Yuri Pichugin
 
For my second research year in the cryonics institute (CI) I was able to carry out 67 experiments with rat hippocampal slices performing 200 tasks, 9 experiments with live rat hearts, 18 experiments with perfusion of whole rat heads, and 8 experiments with perfusion of sheep heads.
 
The purpose of all the experiments was to create a vitrification method for CI. I may not report about the concrete results of the experiments because the institute will probably take a patent using the results. Combinations of all best cryoprotective agents were tested as mixtures for vitrification using live rat brain slices and the functional K/Na ratio assay. Several  vitrification mixtures could cryopreserve the brain slices with about 75% survival.
 

The best vitrification mixture could pre-serve the live brain slices with 85% survival after vitrification to -135oC. The CI glycerol method gave only 20% brain slice survival in the best freezing conditions. 85% and 20% is a big difference.

I tried to test the best vitrification mixture for live rat hearts too. A heart can recover according to the principle: all or nothing.
 
There will be coordinate heart beating or only some fibrillation which will stop during incubation of the heart. Unfortunately the rat hearts could not recover after using the best vitrification mixture even without deep cooling. All known cryoprotective agents are toxic for live organs in high, vitrifiable con-centrations (55-70%), or they cannot protect the organs from freezing injuries in lower concentrations. Cryobiology cannot still create a cryopreservation method that can protect live organs such as hearts, kidneys, livers, and others with complete recovery for transplantation.
 
Today cryonics in contrast to modern cryobiology should not wait for a  completely perfect cryopreservation method because legal dead patients already have defects of human nature that resulted in their death and all after-effects should be cured of future medical technologies. 85% survival of brain tissue is a good result in comparison with the previous cryopreservation CI method and so we should elaborate the better method for whole patient brains and bodies. So, the vitrification method should be tested not only on brain slices but also on whole live animal brains.
 
When I stared to work with whole rat heads I had an obstacle in a form of the rat blood-brain barrier. The barrier was much less penetrable for cryoprotectants than the human and other mammals such as sheep, rabbits, cats, dogs and so on.
 
My recent experiments with cryoprotectant perfusion of sheep fresh dead heads demonstrated that the sheep blood-brain barrier is more penetrable even for glycerol than the rat one. However, a high degree of brain dehydration was observed side by side with the better cryo-protectant penetration.
 
Unfortunately the cryonics institute was not allowed to work with live animals except rats without licenses. To get the licenses is too expensive for the institute. Dead sheep heads are not good for this purpose. I need to use live rabbits in order to employ the sensitive functional K/Na ratio assay for live hippocampal slices.
 
 I can perfuse rabbit heads with cryoprotectants, cool them to -130oC, keep at this temperature, rewarm, wash out them from cryoprotectants , and prepare hippocampal slices from the washed rabbit brains to evaluate their survival by K/Na ratio assay. I will be looking for a possibility to rent a small room at local universities which have the license to work with live rabbits legally.

My work with live rat brain slices was very useful and the results of the work did not lose their significance for future experiments with cryoprotectant perfusion of whole heads because cerebral cells of mammals are not practically different from a mammal to a mammal.
 
If one can make experimental vitrification conditions for cerebral rabbit cells the same as for rat brain slices, cell sur-vival for these cases could be the same in within experimental errors. It has been verified that cell survival in vitro (for brain slices) and cell survival in vivo (for a whole brain) were similar, for example, for toxic compounds or drugs, if the blood-brain barrier was sufficiently good penetrable for these substances.
 
My experiments with dehydration of rat brain slices by diffusion and with dehydration of whole rat brain tissue by glycerol or sucrose perfusion of  the rat heads showed almost the same cell survival according to the K/Na ratio assay.
 
I have two sorts of plans for my future research. The first is an ideal plan for obtaining best results.
 
1.  To determine degrees of dehydration and glycerol penetration for the postmortem human blood-brain barrier at 0oC in the standard conditions. The human cadavers have to be relatively fresh, namely they should be kept at 0oC not longer than 12-24 hours.
 
2.  To determine what type of animal is closest to the human in the respect of their glycerol penetration through the blood-brain barriers. Rabbits, cats, and small dogs should be used. It will be a selection of a proper animal model for subsequent researches.
 
3.  To select the best vitrification mixture of the good vitrification mixtures using the proper animal model and the K/Na ratio assay and  electrophysiology.
 
4.   To test the best vitrification mixture using relatively fresh dead human cadavers and trying vitrification of their heads at -130oC.
 
5.  To study a possibility to cool the human heads to -196oC without cracking.
 
Fulfilling the plan in the USA would be very difficult and expensive for CI. I think it might be possible in Russia in collaboration with Russian cryonicists and scientists.
 
My second plan is to work with live rabbits in Michigan area.
 
1.  To find a optimal method of introduction of the best vitrification mixtures into rabbit heads in order to avoid excessive brain dehydration because it is one of strong harmful factors. For this to determine optimal technical parameters of cryoprotectant perfusion: a rate of cryo-protectant administration, temperature and a rate of its decreasing, and a rate of increasing cryoprotectant concentrations in the vitrification mixtures.
 
2.  To verify complete vitrification of the rabbit heads optimally saturated with the best vitrification mixture cooling them to -130oC.
 
3.  To find a optimal method of washout the rabbit heads from cryoprotectants and evaluating results with the use of the procedure of the brain slice preparation from the washed brains.
 
4.Based on the results, to calculate the technical parameters of the vitrification method for sheep and human heads.
 
5.  To verify the parameters for sheep heads using the vitrification method for them practically.

 

Chairman's Report on the Year at Cryonics Europe

Chrissie de Rivaz

The massive media attention in UK after the New Scientist competition last September, seemed to continue for some months. I made personal appearances on two popular UK chat shows and several other members were interviewed for a number of magazines. We even gathered a few new members, some of whom have signed or are in the process of signing with CI. Mark Walker has been acting as Membership Secretary for Cryonics Europe and reports that there are currently nine new members in the process of signing. One might argue that only a few new members was a pretty poor result after so much media exposure but it is hard to pinpoint what makes someone reach their decision. It could take several years before some are able to reach the decision as a result of these early 'seeds' coming to fruition. I see our role as educators and never as salesmen, a long slow process as any teacher will agree. One good thing is that I hear people talking about cryonics much more nowadays and I've even given 'talks' to people I meet when walking my dogs!

Several students contacted us during the year. It seems that cryonics is a popular subject for media studies, journalists and film makers as well as PhD topics and subjects for Masters degrees.

In April I went to Paris to participate in a live debate on French Television. Facing a sceptical opposition of eminent scientists, I confess I was unable to make a great impact but hope I represented our view in some way. It was an interesting experience and I enjoyed conversation with Yvan Bozonetti who hopes to organise a French group at some stage.

Alan Sinclair has continued to work tirelessly to improve our own equipment and expertise as a stand-by team. There have been a number of training session during the year, following the long-distance session at out home last year, when the Mobile Perfusion Unit made the 300 mile journey most successfully. Alan has since perfected the perfusion system with arrival of the new pump and continues his research and reporting in a way we can only marvel at. Undoubtedly, without his enthusiasm, we should never have reached the point where we are ready to go at a moment's notice. I should not omit to thank the members of the standby team who have attended training meetings so regularly and to Alan's wife who always feeds us all!

In January 2003 we had a visit from Charles Platt. It was a cordial meeting and he was most willing to share information and discuss future possibilities. Obviously, there were a number of differences between our protocols but we would not allow this to prevent harmonious exchanges.

We discussed the possibility of co-operation for standby and ways in which we might some day share equipment and expertise. I was invited to join the Alcor UK meeting. The outcome of this was that they prefer to assemble their own team and equipment but would be willing to assist us should the need arise and were reticent to use our team. At least there are a few of us who have a spirit of co-operation and I felt that a few minor bridges can be considered 'under construction'. There are surely too few cryonicists, especially in UK, for us to bicker.

In early September, John and I hosted what has become an annual meeting in Cornwall and we had several people attending to inquire about cryonics as well as a funeral director from the South West, who seems willing to learn our requirements and become a participating member of the organisation.

This past week, Ben Best took the time to visit UK and discuss our views and see our equipment for himself. He will doubtless have his own comments to make but we found his enthusiasm encouraging and his willingness to listen to our views a good sign for the future, should he be elected President.

We all send our grateful thanks to Robert Ettinger for his tireless work and encouragement over the years and wish him a slightly less demanding future role with CI. I'm sure everyone will agree, without his foresight and inspiration, we wouldn't even know each other, let alone have a distant future to look anticipate. Thank you Bob, and everyone at CI.

 

 
CRYONICS SUPPORT GROUPS  WORLDWIDE
 
UNITED KINGDOM:
 
There is a large, enthusiastic and active group that meets every month under the name CRYONICS EUROPE.   Visit them at: www.cryonics-europe.org. Activities include discussion, CI standby team training, videos,and social events.  All visitors, and new and prospective members are welcome! Please contact:  Mark Walker, C.E. Membership Manager  at davros@....  Tel.UK:
01543-674129, Mobile: 07970-254948.

NETHERLANDS:
 
This is a very keen and growing group anxious to expand.   Contact George Overmeire at Giorgio@... or telephone +31-(0)6-51-454237

IRELAND:
 
Peter Thornbury and his wife are attempting to organize a CI group in Ireland. Peter has homes in both the north and south of Ireland, and welcomes any contacts.  He may be contacted by mail at:  Peter Thornbury, 50 Lough Road, Lurgen, County Armagh, North Ireland.  Email messages for Peter Thornbury should be sent via the UK group. (See above.)

BELGIUM:
 
A new website in Dutch and French is being setup for Belgian cryonicists. Contact David Verbeke at: davidverbeke@...,  or email  cryonicsbelg@... for further information.
                                                      
CANADA:
This is a very active group that recently participated in Canada's first suspension. President, Christine Gaspar, Vice President, Gary Tripp, Secretary/Treasurer, Ben Best. There is a sub-group called the Toronto Local Group. Meeting dates and other conversations are held via the Yahoo   groups address: cryonicssocietyofcanada@yahoogroups.com
 
DENMARK:
 
A new Danish support group has emerged and is online -- the Danish Cryonics Support Group. Contact them at: http://www.cryo.secureid.com, or at: david.stodolsky@...
 
JAPAN:
 
Hikaru Midorikawa, President of the Japan Cryonics Association is attempting to reach out to anyone living in Japan, and interested in Cryonics. He can be reached at: Hikaru@...
 
AUSTRALIA:
 
Theo Tatton, CAA's Executive Officer advises us that the CAA has a bulletin board: Caa-list@...  Their  Public Relations Officer is Phillip Rhodes. They have an annual meeting alternating between Sydney and Melbourne. Their mailing address and phone number are: P.O. Box 57, Hampton  Vic. 3188  Australia  Phone 61-3-9-9589-6236
 

MEET ALAN SINCLAIR
 
I am Alan Sinclair 65 and live with my wife Sylvia in the south of England we have four children.
 
I went to School at Pitmans Collage, a school specializing in academic qualification, short hand and typing, four languages were high on the curriculum and we were encouraged to become doctors, diplomats or lawyers at the very least.
 
You can imagine the horror of the head master when I told him I wanted to be an engineer. He was horrified and had no idea which way to point me stating, Pitman's had never been asked to find such a position.
 
I had hated school with a passion, I hated every minute I attended and was only in this god-forsaken place because I had the misfortune to pass the exams that suggested I was bright.
 
I suppose I was quite bright, but I now know I was also dyslexic, a condition not recognized in those days, which makes going to a secretarial college a total nonsense.
 
I had always wanted to work with my hands and the thought of sitting at a typewriter all day in an office gave me nightmares.
 
I trained as an engineer and a part time racing driver and enjoyed every minute of it. To this day I will only pick up a pen or go on the computer to write if pressed, but with the introduction of spell check I do have a chance of being understood.
 
Unfortunately, in my late teens, I had a nasty accident while showing off on the track and broke my neck.
 
I was extremely lucky because after being plastered up and being told I may never walk, I came across a Chinese osteopath in Wimbledon where I was living at the time.
 
Today this would not seam strange, but in the fifties, it was as strange as cryonics today. Alternative medicines of any kind was looked upon as crazy by the medical profession.
 
In fact, the day I was to measure for a body support, I walked into the hospital, and proudly showed the doctor I was out of the chair, able to walk freely with little pain and stated what wonderful results the osteopath had produced.
 
Instead of looking into to benefits, he discharged me and said he would not see me again because I had gone against medical advice. (much the same as we experience today if we mention cryonics to our doctors).
 
Because of limited ability lifting for a while I decided to go into electronics where I stayed until my mid thirties, I had several shops and always employed a secretary while I was happy to work on the shop floor.
 
As the big companies took over the domestic market I decided it was time for another change in direction and opened a nursing home for the over sixties. As I am now over sixty I retired before they took me over!!!
 
I was about forty-nine and had already spent some years as a nursing home owner when I heard about cryonics.
 
From quite a young age I had been aware that no matter what we achieved life was to short. This came to mind first when the King died, I was only fourteen and this was the first time I had considered the fact that even very important people with all this money still end up dead.
 
This thought did not dominate my life and in fact was soon forgotten, I am not a depressive but every so often this fact of life would service and I used to think what a pity people could not put the same energies into extending life as they do in killing.
 
I first came across cryonics through a weekly TV program run by a Dr Miriam Stoppard which tackled  subjects that were thought to be controversial  and on this particular week it was the turn of cryonics.
 
Dora Kent had just been suspended (along with the publicity) Dr Martinot a French doctor had popped his wife in a freezer a couple of years before and a couple of UK members who had already signed up, although it wasn't all positive but I thought what a GREAT idea.
 
I spoke to a doctor friend of mine and we came to their conclusion there was a outside chance it may work.
 
I contacted Alcor because they were the one's represented on the program and later met Mike Darwin on a visit to the UK.
 
My impressions were what a great bunch of chaps these people were, they seemed be the only people I had met that had there priorities right they were trying to save life.
 
The more I learned the better it became. A leading person in cryobiology working on vitrification assured us this new process was just round the corner (that was in 1989!!!!)
 
Rightly or wrongly, I concluded that without a proper unit to perform a suspension my chances of being revived would be compromised.
 
As all the male side of my family seamed to die before sixty, and I was forty nine by this time, I felt a degree of urgency in setting up a facility.
 
This was opened in 1990, being a bright sort of chap!!! I new if we had a facility, equipment and enough advertising we would have hundreds of new members in a year or two (This is possibly the biggest mistake I have ever made in my life).
 
We had a international cryonics conference at Gatwick, spoke with almost every new paper in England (on the front page of many) and spent months with the TV and press full time and yes we had two enquiries. The UK wasn't ready for cryonics.
 
Like all newcomers, I just couldn't believe it, why couldn't they see what a wonderful opportunity cryonics offers? I still feel this way today but now I have given up bashing my head against a brick wall.
 
In those days before computers, email and even faxes, there was a bitter rivalry between Alcor and CI (at least Alcor thought so) but I insisted if the UK were going to offer a suspension team it had to be for ALL. Therefore, I persuaded Alcor to allow CI members to have access to the UK method that I felt was better at that time. I sill feel the same that we should all work towards the best suspension for all and now I am a CI member our suspension group Cryonics Europe is made up of Alcor and CI members.
 
I strongly feel that while we are small in numbers we should help one another to get the best possible suspension no matter whom our service provider will be and the fact that some in cryonics don't want this I find extremely frustrating. Why is something so important so hard to achieve.
 
My wife is very supportive even when I spent our retirement fund on the facility!!! Most of my friends realize that I am family sensible and look at everything from a scientific view so wouldn't embark on this without a great deal of thought.
 
My children are supportive although they haven't signed up yet.

There were a number of friends that couldn’t understand where the profit was and without profit why was I involved.
 
They hadn't realized the biggest profit is life and no amount of money will buy that.
 
My main hobbies are cryonics and cars. A great deal of my time has been spent in setting up a suspension team and equipment but I must confess I spend far to much time on restoring old cars. My latest project is a 1933 Lagonda, which I bought in boxes. My wife tells me the best way to sell me a car is to cover it with rust, take it apart and hide it!!!!
 
I haven't visited CI because since my car accident I have been agoraphobic and travel little outside Britten. The first time I visit CI I don't suppose I will remember it, but I hope to remember coming home. I have no idea what will happen if they revive me, but cant cure my agoraphobia!!!  
 
Today I help the best way I can to support CE and CI, I know one day I will need their support far more than they need mine. Please do everything you can to help CI and its research team to help you. 
 
 

 
AN AUSTRALIAN CONVERSATION
 
A cryonet conversation between two "Aussies, Peter Merel and Simon Carter."
 
In Q1 '04 I'll be moving back to Australia, and will stay there for the foreseeable future. I expect to maintain dual citizenship (Australia/USA) and I'll be living about 15 minutes from the nearest hospital (I've bought the Limpinwood Tea-house outside Murwillumbah). I presently enjoy membership in Alcor via life insurance, and I would prefer to continue this membership if possible. Alcor provides little guarantee of service to non-US residents, however, so it seems I might have to jump ship.
 
I've read the CAA website at http://prix.pricom.com.au/caa/index.html and also CI's brief comments on its Australian service at http://www.cryonics.org/euro.html. But before doing anything drastic I thought it best to ask here:
 
If you were in this situation, what would you do? If you represent one of the orgs, what can you offer Americans living in Oz? And if you're an Australian cryonicist, CAA or not, what particular chal-lenges do you face these days in Oz?

Oh, and for those that would say, "just don't go", sorry mate, in my estimation the chances of cryonics working in my particular case aren't sufficient to counterbalance the risks of just living in the US today. Actually that's a good question anyway: how much quality of life are you willing to trade for quantity of life?
 
Peter Merel.
 
Peter Merel recently asked on Cryonet where CI's Australian members live.  Robert Ettinger replied. "We can't generally identify them without permission, but the towns are: North Clayton, Glebe, Adelaide, Pyrmont, Sydney, Pymble, Bridgetown, Sandy Bay, Hampton, and Melbourne."   Mr. Merel apparently is going to be pretty far to the northeast in Queensland, so another mortician closer to him should be found, which should not be difficult
 
From: Simon Carter:
 
Hi Peter,
 
Nice to know another cryonicist is heading in my general direction! I've been living in Brisbane for the last five years. I look forward to meeting you.
 
Peter:  I'll be out of the way, but not that far out of the way. Murwillumbah  is in New South Wales, about 1 hour south of Coolangatta and 1.5 hours south of Brisbane.
 
Arguably one of the nicest spots on the continent Peter!
 
Peter: My teahouse has a superb view of the NSW/Old border  range, part of the eroded caldera of Wollumbin now covered with virgin  rainforest. A few snaps of same are at
http://www.greencheese.org/LimpinwoodTeahouse .
 
Envy!
 
Peter:  Furthermore at least some of the time I'll be ably assisted by a dear friend of mine who happens to be a qualified and experienced cardiac perfusionist. Of course being just 41 and in good health I rather expect to employ her skills in the garden than the operating theatre, and I haven't canvassed how she feels about this particular brand of lunacy...
 
Now that sounds a most useful friendship - I'm not sure I can advise you on broaching the "particular brand of lunacy" tho'.
 
Peter: I've signed up with Alcor and am a member of the Cryonics Association of Australia.(CAA) I'm unsure whether there are any signed up cryonicists in SE Queensland/Northern NSW but have a vague idea there are a couple. You could seek further information from the CAA. One problem cryonicists certainly have in Australia is that we are few in number and highly dispersed. To partially counter this we have, as Bob mentioned, arrangements for basic suspension services to be performed by several mortuaries.  I'm trying to avoid facing the likelihood that if I should encounter a need for emergency suspension I'd most likely be completely screwed.
 
I would not say "completely screwed" as even emergencies can result in some warning time before pronunciation of 'death'. Even in the US folk have been subjected to prolonged delay. Nevertheless such matters are of concern to us here.
 
Peter: Just in case anyone's contemplating starting a new org or extending an existing one I should point out that Australia is a tectonically stable continent with no real winter,
 
Brrrr! It was 5'C last night here in Brisbane.
 
Peter: cheap land,
 
Outside the cities.
 
Peter:  proven democracy, world's  best engineers and doctors, no religious extremism, the Asian market on  the door-step, an active euthanasia lobby, a government open to research  on stem cells and cloning, and even a number of media personalities willing to come out and say they're signed up for cryonics ...
 
I'll back you on all the above except for the latter. Who are they?
 
Peter: Hmm. You know there might just be enough wealthy madmen in and around  Byron to find backers to start an org. Damn,  Ah well, no harm in talking to a few of 'em .. Didn't Phil Rhoades start down this  path?
 
Yes, you should get together with Phil. Even post your thoughts to the CAA list. I hope some of the other Australian cryonicists will add their thoughts and email you/CryoNet.
 
Long life, Simon
 
Simon
 


 
LIFE EXTENSION NEWS
 
SURVIVING A HOSPITAL STAY 
 
Everyone is likely to stay in a hospital someday or have a loved one there. When that time comes, go where the experience is, Years of research show that for a range of medical procedures, including angioplasty and many cancer operations, patients  find the best results at hospitals perform them often. The National Quality Forum urges doctors to refer high-risk surgery patients to centres with "intensivists" on staff. Johns Hopkins University researchers found that patients undergoing complicated abdominal surgery were up to three times as likely to survive if the ICU employed one of these doctors--who are specifically trained in intensive care--as patients in hospitals without this benefit. Only one in 10 hospitals has these specialists, though the proportion is likely to grow.
 
Accreditation is also a crucial indicator of hospital safety. Quality Check, the consumer Web site of the Joint Commission on Accreditation of  Healthcare organizations, is simple to use. Go to www.jcaho.org/qualitycheck/directry/directry.asp; type in the hospital's name to see whether it comes up.
 
Teaching hospitals have the greatest expertise in surgery and intensive care. But they also have doctors in training, fresh out of medical school. If you have reservations about anything a resident does, ask to talk to the attending physician. Each new class of residents starts July 1. if you have a choice, schedule your surgery from January through June.
 
 Finally, having a friend or relative stay by your side tremendously lowers the risk of a mistake, says internist Marie Savard, M.D., author of a book on avoiding medical errors. Many people have trouble asking someone to sit with them when they're sick. But those same people likely wouldn't think twice  about dropping everything to be with  some one they care about. So don't be afraid to ask if you're facing a hospital stay yourself--or to organize shifts of friends and family to visit the person you love.  Adapted from HEALTH
________________________________
THE BUZZ ON HONEY
 
The general public is showing renewed interest in honey. In days gone by, honey was used as a wound healer, laxative, and a salve for sore eyes, among other things.  Most people think of honey as something to pour on pancakes or drop into hot tea.
 
Now researchers are exploring other uses for it:
 
To lessen the ill effects of radiation therapy for cancer of the head or neck.
 
To improve oral health.
 
To preserve food.
 
To boost antioxidants.
 
To enhance athletic performance.
 
As an aphrodisiac.
 
Recently, The Royal Society of Chemistry in London conducted a survey of newlyweds, asking them to sip honey mead every night for 30 days, and to document its effects. No word yet on the results, if any.
 
The Journal Supportive Care in Cancer recently published the results of a study at the University of Malaysia, showing honey may benefit patients who suffer swelling, sores and inflammation in the mouth after radiation therapy.
 
Researchers at The University of Illinois have found that honey, when mixed with ground turkey, slows the oxidation process that gives it that leftover taste after a few days. They have also found that honey has the same level of anti-oxidants as some fruits and vegetables.
 
In honey, there's little water available to promote the growth of bacteria and yeast. Also honey's natural acidity inhibits some pathogens, and it has tiny amounts of hydrogen peroxide, as well as other substances that seem to contribute to it's antibacterial effect, according to the National Honey Board.
 
Granville Griffith, a beekeeper in Northern Kentucky has been using honey as a cure-all since childhood. Recently, after cutting his finger with a knife, he washed it and applied honey in the same way Neosporin is used.
 
In less than two weeks, with a couple more applications of honey, it was completely healed with no scab and the scar is minimal. Adapted from FLORIDA TODAY
________________________________
HEART HEALTHY PEANUTS
 
Two new varieties of  peanuts are expected to reach grocery shelves early next year. Developed by the Agriculture Department, and University researchers, the peanuts contain high levels of oleic acid, a healthful monounsaturated fat.
 
Such fats raise the level of good cholesterol that reduces the risk of clogged arteries, and lowers bad cholesterol that damages arteries.
 
Oleic acid appears in most peanuts. A handful, 10 grams of conventional roasted peanuts can contain 5 grams of fat---55 percent of which is oleic acid. Conventional peanuts also contain as much as 20 percent saturated fat---an artery clogger that can raise a person's risk of heart disease.

LETTERS
 
JOE KOWALSKY wrote with comments about two recent Immortalist articles. One was the QUICKIES piece  "Seventy Five percent of sudden deaths during sex occur in extramarital affairs." (May-June 2003) The other was in reply to Jim Yount's article "Watchtower Pro Cryonics?" in the same issue. ( Joe has been a CI director for a number of years, he and his wife Jennifer live in the Detroit area.)
 
"I mentioned the "Quickies" article 'Seventy Five Percent of sudden deaths during sex, occur in Extramarital Affairs'  to my wife and wondered aloud whether the 'sudden deaths' were, perhaps, not so sudden but rather that in the 'affair' situations the partner hesitated in calling for medical attention. 
 
My wife, without missing a beat, responded 'maybe it is from being shot by the spouse.'  (Actually, she said wife"!)
______________________________________________________________________________________
 
Regarding Jim Yount's piece "Watchtower gives 'Thumbs Up' to Cryonics?"  The Watchtower magazine speaks, as I understand it, for Jehovah's Witnesses as a whole.  They believe that the Bible dictates that true Christians speak with one voice, based on the Bible and God's position as elucidated therein.  There is, therefore, never a "by-line" in a Watchtower article.  The articles are not by one author but are, rather, gone over by many people to ensure that they speak what is the Witnesses' understanding of God's word. 
 
I, too, am disappointed that the Witnesses do not "allow for the possibility that God would work through man to accomplish this 'life everlasting,' but that is precluded by their reading of The Bible.  They believe that resurrection of the dead and everlasting physical life on a paradisiacal Earth will come directly from God and his assistant Jesus and that The Bible describes the specific order of events by which this will be brought about.  
 
On the other hand, because the Watchtower speaks for the Witnesses as a group, your comment that "at least one Christian writer believes that there is nothing wrong with the desire to be immortal, and sees the desire fulfilled as physical immortality upon this Earth . . ." can be expanded to: it is heartening that some six million Christians (the approximate number of Jehovah's Witnesses worldwide) believe that not only is there nothing wrong with the desire for everlasting life, but see that as a natural part of being human and expect that it will eventually come to pass. 
 
(This is my understanding of Witness Theology.  I do not claim to be an expert and apologize if I have erred in any of my comments in accurately reporting their positions.)
 
I should note in passing that the Witnesses - as well as many other Christian and Jewish denominations - believe that Adam and Eve were created with the intention that they would live forever; that the Human body was not designed to die.  Only after eating the fruit did God follow his admonition that "you shall surly die" and make their bodies limit their duration - a trait which has passed genetically (according to these beliefs) from then on.
 
[The word "immortal" connotes self-sustaining incorruptible life.  Even perfect humans with the ability to live forever could not be self-sustaining (they would need to breath, eat & drink to remain alive and their bodies, although perfect, would not be "incorruptible.")]
 
My e-mail address was wrong at the end of Jim's article.  It is peterson@....
 
Joseph Kau writes "Our Association, here in Australia, has a bulletin board, just in case you were not aware of its existence."   Here it is:  caa-list@...  (we weren't!)

Getting To Know Ben Best
 
By David Pascal
 
I first met Ben Best in the autumn of 2000.  I admit I was expecting to be impressed.  I was a new kid on the block back then, barely at CI two years; and, from Robert Ettinger to Eric Drexler to Marvin Minsky and many more, cryonics was certainly not poor in terms of persons well-known for their intelligence and commitment.  Ben Best was one of them, and was certainly a name to conjure with.  Traveller, author, activist, Ben was one of the people who had founded the Cryonics Society of Canada, and was one of the founders of CryoCare, and was committing both time and funds to the Institute of Neural Cryobiology's efforts to improve human brain cryopreservation.  Quite a few people in cryonics are brilliant, and talk brilliantly; fewer act.  Ben acted.  With significant effect.
 
So I expected to be impressed; and I was.  Not so much by his knowledge and learning, then, as by his sense of responsibility.  CryoCare was in trouble, because, through no fault of its own, other service providers it had counted on were collapsing.  And far from deserting the sinking ship, Ben had come to the Cryonics Institute to do his very best to see that Cryocare's patients were assured of safe shelter with CI, should that become necessary.
 
This was before the CryoSummit; relations between cryonics organizations were not warm at the time.  But to Ben, patients mattered more than factions.  They did to CI as well, which is why he came and why he was welcomed to make his case.  It was a sound and solid case; and it impressed us all as coming from a sound and solid human being.
 
And shortly after, in the wake of Cryo-Care's own subsequent passage into stasis, Ben Best joined the Cryonics Institute.  This was not a move that was much celebrated in certain corners.  CryoCare had largely been formed by Alcor members who had become disaffected with that organization.  CryoCare having faltered, the general sense was that the Revolution had failed and the rebels should now return home.  Many did.  Ben did not.  He turned to CI.
 
Why?  I've never really asked, but I think he saw something during the CI meeting that he did not see in Alcor at that time - namely, a willingness to change, a determination to develop and improve.  Far from discouraging potential members with high prices and complex paperwork and an elitist sensibility, CI was trying to open the door further by keeping costs low and things simple and to actively reach out and inform the public through its mushrooming web site.  Far from repeating the same methods, CI was reviewing its protocols, improving its methods, and looking to develop a lab doing, in short, what CryoCare had been doing:  looking at itself and cryonics operations critically, and adjusting and upgrading things to achieve continual renewal and improvement. In short:  thoughtfully working to make itself ever better.
 
Whatever his reasons, he did join.  And as many know, his rise in the organization has been meteoric.  Nominated for Director the first year; advisor to the Board the next year; elected as full Director last year.  And, now, President, succeeding the legendary figure of Robert Ettinger at the helm of CI.
 
Why?  Why Ben Best?
 
From the point of view of his resume, the question answers itself.
 
Administrative experience?
 
Ben Best has already served as President of a major cryonics organization, Cryo-Care.  He's been President of the Cryonics Society of Canada and a leader of its Toronto Local Group, one of the most active, rapidly-growing, and successful such cryonics support groups in the world. He directed the Institute of Neural Cryobiology as President, where he worked with Dr. Yuri Pichugin, CI's current Director of Research, on the Hippocampal Slice Cryopreservation Project (HSCP), where he helped produce some of the more significant advances in the field ever recorded.
 
Financial expertise?
 
Ben Best has served as career computer programmer specializing in database applications specifically for the financial industry and for major banking institutions.  He's also served as Treasurer for the Toronto branch of Mensa.
 
Breadth of experience?
 
As a member of Alcor, CryoCare, CI, the CSC, Ben has pretty much seen it all first-hand.  How things operate across the board.  What works, and what doesn't.  As a traveller and 'roving cryonics ambassador', Ben's worldwide travels have included attendance at virtually every significant cryonics conference ever held. Is there a prominent cryonicist anywhere that Ben Best has not met or contacted in some way or other?  I can't think of one. 
 
Ben is universally known in the cryonics world - and universally respected.  Ben's met cryonicists in Australia, New Zealand, Europe, the United States, Canada.  His arrival at CI headquarters in Michigan this year was directly preceded by his visit to John and Chrissie de Rivaz, Alan Sinclair, and other Cryonics Europe representatives in England.  Cryonics is a phenomenon of transnational, universal scope; and with Ben Best, CI will have a leadership experienced in and at ease with that universal scope.
 
Ability to communicate?
 
Ben is well known as both an author and a lecturer, and his extensive writings on cryonics at his web site at www.benbest.com are generally admitted to be one of the most informative infor-mation sources in existence on the subject. His work has been a major resource both for local group efforts such as Cry-onics Europe's operations manual, and has been featured often in The Immortalist and other publications.  He is one of the small handful of people that are deeply knowledgeable about the technical aspects of cryonic suspension; and one of the even smaller handful that has gone to painstaking lengths to make that knowledge freely available to all.
 
Admittedly, there are things about cryonics that can transcend technical or resume considerations.  And, though it may embarrass Ben a bit to have me say this, he's not lacking in those qualities either. I had the privilege of assisting Ben in a small way in the recent suspension of a CI member in Toronto. 
 
The report is on Ben's web site, and it's not short of comments on things that need to be improved and what has to be done better next time.  But it doesn't mention Ben straining to haul a heavy oxygen tank upstairs to the apartment of a dying CI member, or of his taking days from his work and his personal life to sit by an elderly woman's bedside, and keep vigil.  Compassion doesn't appear on resumes very clearly.  But I've seen it appear on Ben Best's face very clearly.  And that recommends him too.
 

What is Ben Like as a person?  Well -- he hates journalists, so he is clearly a man of taste and refinement.  Also, I've visited him at his apartment, and I can't say enough about his magnificent gifts in interior decoration - the place appears to the casual eye to be three thousand books and a laptop.  I speak as a veteran bookworm, true, but you can learn a lot about a man from his bookshelves.  Ettinger and Drexler and Halperin are there, needless to say, but I was pleasantly surprised to see Baudelaire and Santayana and an anthology of French Poetry too.  Tech books?  By the score.  Medical volumes?  A ton.  But philosophy, religion, sociology and art make their appearances as well.  And where the readings are broad, the reader is not narrow.
 
Ben is not perfect, mind you.  Sweatshirt and jeans are much more to his taste than pinstripe suit and tie.  He is palpably morose at having to don the latter for formal appearances as CI President.  Too, he is much into health food, vitamin supplements, and calorie restriction.  And that's admirable, I guess.  But though dinner with Ben can be an intellectual feast, looking down at a mixture of broccoli and wheat germ has never really entranced me.  It may make you live longer, but it sure doesn't motivate you to do so.  His humor, like his oat-meal, tends to be dry, and his honesty is legendary. Never ask Ben Best what he thinks of your tie or haircut.  He'll tell you.
 
But this is only to say that Ben Best is a human being.  A few of us have suspected that.  Is he a good one?  Trust-worthy, likeable? I can only speak for myself there.  I trust him; and I like him.  And I can think of very, very few people who don't.
 
So, is CI in good hands, and should the members be confidant, even happy, at this shift in leadership?  Yes.  It's in fine hands, and they have every reason to be confident. Not least because CI is not only in Ben's hands, but also in the hands of its several intelligent and competent Directors, now including Britain's Alan Sinclair, and the hands of Robert Ettinger too. Robert Ettinger is by no means leaving CI, but is staying on in the post of Vice President.  His advice and input will doubtless be a welcome and shaping part of any decisions Ben is called upon to make in days to come.

Of course, Ben has a tough act to follow.  Just as the Exodus began with Moses and the United States started with George Washington, so cryonics and the Cryonics Institute is in many ways a shadow stretching from the mind of one, very great, man - Robert Ettinger.  Following a predecessor can be easy; following a predecessor of mythic dimensions is not so easy.
 
Can Ben Best do it?  I'm sure he will.  Because, after all, he must, if CI and its members and patients are to be properly safeguarded.  And because great predecessors have great successors as well.  Joshua executed his duties well enough at Jericho, and Jefferson and Lincoln had one or two good points too.  New leaders can do well, and have done well. There's every reason to believe Ben Best will be one of them.
 
At the transition of power at the Annual Meeting, Robert Ettinger gave one of his most moving speeches.  He reminded those listening, not of his own achievements, but of our responsibilities to our patients.  He mentioned the names of people in CI's care that many there knew and loved and remembered -- Andrea Foote, Walter Runkel, Rhea and Elaine and Mae Ettinger, others.  "They are more helpless now than new-born babies," he said, "and all they have protecting them and guarding them is our fidelity and our competence."
 
Fidelity and competence - it's hard to think to two words that better summarize the Presidency of Robert Ettinger at CI these many years.  And, I confess, it's hard to think of two words that better characterize Ben Best's own long efforts to further the cryonics cause.  So in a way, I suppose the torch is not so much being passed, as being upheld.
 
Cryonics has always been a thing of controversy, and no doubt the Cryonics Institute will be weathering future storms beyond the current ones.
 
But I think we have found a very good captain.
 


Statement from the New President of the Cryonics Institute

I feel extremely privileged to have been elected President of the Cryonics Institute. It is no understatement to say that many people have entrusted me with their lives, a huge responsibility.

Fortunately for all of us, many others share in this responsibility, including Andy Zawacki our Plant Manager, Yuri Pichugin our Research Director, David Ettinger our legal counsel, Pat Heller our Treasurer, John Bull our magazine editor. Jim Walsh our primary funeral director and Rudy Matic, who is in charge of marketing and public relations.

The Board of Directors has the collective wisdom of many years of experience in cryonics and l am especially pleased to welcome Alan Sinclair as our newest Director. Alan has been a pillar of strength and creativity for the Cryonics Institute in the United Kingdom.

Robert Ettinger will remain on the Board of Directors and will be our new Vice President. His role as an originator of cryonics as well as his life-long steadfast commitment merits deep respect and gratitude. As Vice-President he will provide continuity and guidance. It is easier to transfer a title than to transfer knowledge and responsibility. I have much to learn from Mr. Ettinger as well as from all those I have previously mentioned.

As a new President my concentration will be on learning rather than on trying to implement changes. I do hope, in the long run, to bring about many significant changes as the Cryonics Institute grows.

I will pursue the vision of fully reversible suspended animation along with the elimination of death due to ageing, disease, accident, murder and suicide. It is my hope that these goals can someday be achieved without the Cryonics Institute ever having to raise prices. I have been very inspired by the creation of a simple, low-cost portable ice-bath and closed circuit perfusion unit by Alan Sinclair. I share Alan's idea that good technology and low cost need not be mutually exclusive.

Aside from learning, however, I am initially concentrating energy on the creation of a member's database. I want to create an e-mail forum for members and voting-members of the Cryonics Institute. John de Rivaz has offered to moderate these forums. I believe that CI has a great-untapped pool of human resources in the knowledge, talents and ideas of our members. To ensure maximum participation, please e-mail your current e-mail address to CIHQ@....

You may mention your occupation, special expertise, or ideas you have for improving CI. The more we work together and the more of us we have helping, the grander the dreams we can all fulfil.

Ben Best, President Cryonics Institute


Small Print:

For more information about cryonics or Cryonics Institute and how to become a member, visit our web site at http://www.cryonics.org.

We encourage readers to forward issues to friends and interested parties. Please send any suggestions or comments to Long Life by emailing John@...

Long Life would like to thank Longevity Report, Wired News, InfoBeat, The New York Times, The New Scientist, Nanodot, Slashdot, contributors to the Extropian and CryoNet mailing lists, members of the Cryonics Institute, and others, for helping provide some of the free public information used in Long Life.

(Disclaimer: CI does not necessarily encourage or advocate the use of any products or practices mentioned in its newsletter.)


--
Sincerely, John de Rivaz: 
http://John.deRivaz.com for websites including Cryonics Europe, Longevity Report, The Venturists, Porthtowan, Alec Harley Reeves - inventor, Arthur Bowker - potter, de Rivaz genealogy,  Nomad .. and more

#25 From: "John de Rivaz" <John@...>
Date: Sat Oct 18, 2003 10:14 am
Subject: Long Life 9
longevityrpt
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Long Life: the Cryonics Institute newsletter

September/October 2003 -- Volume 2, Number 9

Welcome to Long Life -- the electronic newsletter of the Cryonics Institute. We're here to update you with brief cutting-edge news, updates, links, and information about the latest scientific, medical, health, anti-ageing, and social developments relevant to CI's goal of saving, preserving, and extending human life. Long Life may also include news about Cryonics Institute events and member activities and opinion. We welcome your feedback, and encourage readers to forward issues to friends and interested parties.


 
CI and general cryonics news
 
See Immortalist highlights sent as a separate email
 

 
General News Items

Important Note: A lot of these items are from sources designed for public consumption and contain no references or further information. It is up to readers to do their own web searches or whatever for further information.

 
Many of the stories here came from InfoBeat, an internet based news service. Unfortunately they have reduced their coverage of scientific issues, at least for the moment.
 
Undated or earlier items:
 
Alzheimer's surge predicted
 
The number of people with dementia is set to rise.

An "epidemic of Alzheimer's" over the next few decades could be far worse than previously thought, experts suggest.  The number of people with Alzheimer's could treble by 2050, say US researchers, as the population surges and existing patients live longer.
 
more on http://news.bbc.co.uk/1/hi/health/3161523.stm
 
Painkillers protect against Parkinson's
 
The drugs may have a protective effect. Anti-inflammatory drugs may be able to reduce the risk of someone developing Parkinson's disease later in life. However, while the study may provide clues to future therapies, doctors are not recommending people taking drugs such as ibuprofen long-term.
 
 
Exploding the food myths
 
Is a cooked breakfast always unhealthy?
Do we really know what is good for us?
Is 'low fat' always a good thing?
And is a cooked breakfast always unhealthy?
 
There is so much food confusion around that the UK's Food Standard Agency (FSA) has decided to debunk the myths and test the consumers.
 
more on http://news.bbc.co.uk/1/hi/health/3030271.stm
 

 
NASA Ames Research Center, Moffett Field, Calif.     August 11, 2003

RELEASE: 03-57AR

RESEARCHERS FIND ANTARCTIC LAKE WATER WILL FIZZ LIKE A SODA

Water released from Lake Vostok, deep beneath the south polar ice sheet, could gush like a popped can of soda if not contained, opening the lake to possible contamination and posing a potential health
hazard to NASA and university researchers.
An important implication of this finding is that scientists expect oxygen levels in the lake water to be 50 times higher than the oxygen levels in ordinary freshwater lakes on Earth. Organisms there will have developed methods to deal with this oxidative stress. [ not from NASA: Maybe some of these can be applied to life extension stragegies in humans at ordinary levels of oxygen, leading to longer lifespan. ]

A team of scientists that recently investigated the levels of dissolved gases in the remote Antarctic lake found the concentrations of gas in the lake water were much higher than expected, measuring 2.65 quarts (2.5 liters) of nitrogen and oxygen per 2.2 pounds (1 kilogram) of water.  According to scientists, this high ratio of gases trapped under the ice will cause a gas-driven "fizz" when the water is released.

"Our research suggests that U.S. and Russian teams studying the lake should be careful when drilling because high gas concentrations could make the water unstable and potentially dangerous," said Dr. Chris McKay of NASA's Ames Research Center in California's Silicon Valley. McKay is lead author of a paper on the topic published in the July issue of the Geophysical Research Letters journal.

"We need to consider the implications of the supercharged water very carefully before we enter this lake," said Dr. Peter Doran, a co-author and associate professor of Earth and Environmental Sciences at the University of Illinois at Chicago.

Lake Vostok is a rich research site for astrobiologists, because it is thought to contain microorganisms living under its thick ice cover, an environment that may be analogous to Jupiter's moon, Europa. Europa contains vast oceans trapped under a thick layer of ice. Russian teams are planning to drill into Lake Vostok's 2.48 mile (four kilometer) ice cover in the near future, and an international plan calls for sample return in less than a decade.

More on http://salegos-scar.montana.edu/
 
Most Heart Attacks Caused By An Unhealthy Lifestyle

Wednesday, August 20 2003
 
Two sweeping studies released today appear to explode the long-held myth that half of heart attacks result from bad genes or bad luck.
 
The studies, focusing on different populations totaling about half a million people, indicate that about 90% of people with severe heart disease have one or more of four classic risk factors: smoking, diabetes, high cholesterol and high blood pressure.
 
That means the vast majority of the 650,000 new heart attacks each year could be prevented or delayed for decades by quitting smoking, reducing cholesterol and controlling hypertension and diabetes.
 
''If we could eliminate smoking and get people to be fit and trim, we could turn this thing around without unraveling the genes that cause heart disease,'' says researcher Eric Topol of the Cleveland Clinic Foundation. He is co-author of a study involving more than 120,000 heart patients.
 
The research has major policy implications. It suggests that doctors and patients should place even greater emphasis on prevention. The American Heart Association and National Cholesterol Education Program both have emphasized aggressively treating people who have not yet had a heart attack if their ''global risk'' is high.
 
''I think these studies will wake people up and renew the emphasis on traditional risk factors,'' says Philip Greenland of Northwestern University. He is lead author of a study involving almost 400,000 people enrolled in lifestyle studies and followed for up to 30 years.
 
The researchers analyzed data from previous major studies. The reports appear in today's Journal of the American Medical Association.
 
''These papers are just amazing. They're basically blowing away the myth that only half of the people who have heart disease have traditional risk factors,'' says John Canto of the University of Alabama-Birmingham. He co-wrote an accompanying editorial in the journal.
 
None of the researchers could identify the source of the erroneous assertion, cited by experts for years. ''It's folklore,'' Greenland says.
 
A separate analysis in the journal concludes that there isn't enough evidence to conclude that so-called new risk factors for heart disease, including inflammatory proteins called Lipoprotein-A, C-reactive protein and homocysteine, add much to the predictive value of the four classic risks.
 
To see more of USAToday.com, or to subscribe, go to http://www.usatoday.com
 
Nanoparticles to pinpoint viruses in body scans 
  
19:00 20 August 03 
 
An injection of magnetic nanoparticles into your bloodstream could reveal precisely where harmful viruses are lurking.
 
The particles are coated with antibodies to a particular virus, so they will form clumps that should be visible on conventional body scans if that virus is present. The team working on the technology, from the Harvard Medical School's Center for Molecular Imaging Research in Charlestown, Massachusetts, have already managed to detect viruses in body fluids and tissue samples.
 
They hope to be able to detect viruses in patients' bodies within a couple of years. Much of the technology has already been tested in humans, so the scientists are confident that it will be safe.
 
New evidence links virus with breast cancer
 
 
17:58 18 August 03
 
NewScientist.com news service
 
New evidence for a link between a virus and human breast cancer has been revealed in a series of studies by Australian researchers. The virus, dubbed HHMMTV, is very similar to a version known to trigger mammary cancer in mice.
 
The researchers stress that they have not proven that the human form causes cancer in people - but if it does, its raises the possibility of developing a vaccine against the deadly disease.
 
A team at the Prince of Wales Hospital in Sydney published research in March that found the virus in 19 of 45 breast cancer biopsies taken from caucasian Australian women (Clinical Cancer Research, vol 9 , p 1118). In contrast, they identified HHMMTV in less than two per cent of normal breast tissue samples.
 
but nothing about how the virus may spread.
 
Male HRT may raise heart disease risk 
 
10:48 21 August 03 
 
The idea of giving ageing men hormone replacement therapy has suffered another body blow with the discovery that high doses of testosterone increase sleep disturbances that raise the risk of heart disease.
 
"This shows there are risks other than financial ones," says team leader David Handelsman of the ANZAC Research Institute in Sydney.
 
In the US, where drugs are directly marketed to patients, the amount of testosterone prescribed has tripled over the past decade. And while few men in Europe or Australasia currently take testosterone, some private clinics aggressively promote it as a cure-all for male ageing.
 
 
Enzymes Found to Delay Aging Process
Discovery Could Lead to Drugs to Extend Life Span
By Rick Weiss
Washington Post Staff Writer
Monday, August 25, 2003; Page A02

Scientists have found for the first time a way to rev up a potent "anti-aging" enzyme in living cells, an advance they said could speed the development of drugs to extend human life span and prevent a wide range of geriatric diseases.
 
The novel approach has significantly increased the life spans of yeast and human cells in laboratory dishes and extended the lives of flies and worms -- organisms that, on the level of molecular biology, age much as humans do. Indeed, the researchers said, the compounds seem to have the same anti-aging effect as a drastic reduction in calories, the only strategy ever proven to extend life in mammals but one that most people find difficult to stick to.
 
It is too soon to say whether the latest findings will ever make the leap from the lab bench to the geriatrics clinic -- though some may choose not to wait: Of all the compounds the researchers tested, the one that boosted the anti-aging enzyme the most was resveratrol, an ingredient in red wine that has been credited with that beverage's ability to lower the risk of heart disease.
 
 
Scientist In Anthrax Probe Sues Ashcroft, FBI
Wednesday, August 27
WASHINGTON --
 
A former researcher at an Army lab accused Attorney General John Ashcroft and the FBI Tuesday of improperly casting suspicion on him in the 2001 anthrax attacks to fool the public into believing progress was being made in the investigation.
 
In a lawsuit filed in U.S. District Court here, Steven Hatfill, 48, says top Justice and FBI officials violated his constitutional rights ''to promote their own personal and political interests'' when the investigation stalled last summer.
 
Specifically, the lawsuit says the FBI and Justice Department have violated Hatfill's privacy and his Fifth Amendment right to life, liberty and property by interfering with his employment prospects.
 
''This lawsuit is not just about Steven Hatfill,'' said attorney Thomas Connolly, who is representing Hatfill for free. ''It is about the enormous power government officials have. . . . Whatever the government can legally do to Steven Hatfill, it can legally do to any of us.''
 
 
Nanotube television set project
 
September 30, 2003
 
The purpose of the agreement and subsequent effort to develop a 25-inch diagonal, full-color, carbon nanotube (CNT) television prototype is to demonstrate that carbon nanotube televisions in field emission mode have progressed enough to enable high volume manufacturing. The resolution of the display will be compatible with a 60-inch or larger HDTV format display that is the target product.
 
 

Small Print:

For more information about cryonics or Cryonics Institute and how to become a member, visit our web site at http://www.cryonics.org.

We encourage readers to forward issues to friends and interested parties. Please send any suggestions or comments to Long Life by emailing John@...

Long Life would like to thank Longevity Report, Wired News, InfoBeat, The New York Times, The New Scientist, Nanodot, Slashdot, contributors to the Extropian and CryoNet mailing lists, members of the Cryonics Institute, and others, for helping provide some of the free public information used in Long Life.

(Disclaimer: CI does not necessarily encourage or advocate the use of any products or practices mentioned in its newsletter.)

--
Sincerely, John de Rivaz: 
http://John.deRivaz.com for websites including Cryonics Europe, Longevity Report, The Venturists, Porthtowan, Alec Harley Reeves - inventor, Arthur Bowker - potter, de Rivaz genealogy,  Nomad .. and more

#24 From: "John de Rivaz" <John@...>
Date: Fri Aug 8, 2003 10:35 am
Subject: Long Life 8 - Immortalist Highlights
longevityrpt
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Long Life: the Cryonics Institute newsletter

August 2003 -- Volume 2, Number 8 - Immortalist Highlights

Welcome to Long Life -- the electronic newsletter of the Cryonics Institute. We're here to update you with brief cutting-edge news, updates, links, and information about the latest scientific, medical, health, anti-ageing, and social developments relevant to CI's goal of saving, preserving, and extending human life. Long Life may also include news about Cryonics Institute events and member activities and opinion. We welcome your feedback, and encourage readers to forward issues to friends and interested parties.

There are separate issues for highlights from the latest issue of The Immortalist. The reason for this is that otherwise the file is too long for some readers, and also the publication dates of The Immortalist are not synchronous with the start of each month.
 
I would also urge readers to subscribe to the paper issue of The Immortalist (see http://www.cryonics.org/info.html ) as not everything is reproduced in this email version.
 

 
From the Immortalist: 
 
Editor's Corner
News and Views
Quickies
An Imaginary Conversation
Life Extension news
Should Cryonicists Buy Defibrilators?
Statins Go Mainstream
More on Ted Williams
Cryogenic Storage Seminar
Toronto SARS report
Methuselah Mouse Prize
 

 
EDITOR’S CORNER

We’re slowly beginning to think that we’re doing something good here. In this year’s January-February issue we pointed to the current issue of WIRED reporting on the advantages of taking two supplements, Acetyl L-Carnitine and Super Alpha Lipoic Acid, something that we had reported a year before, thanks to Peter Christiansen.

In this issue we report on the eight page spread in the July 13 issue of NEWSWEEK praising the virtues of statins in maintaining cardiovascular health, something that Doug Skrecky did in an Immortalist article at least a year ago.

Now comes a looser FDA ruling, reported in FLORIDA TODAY on how much scientific evidence is required to put a health claim on food packages. The first beneficiary of the ruling are the packers of nuts, specifically almonds, hazelnuts, pecans, pistachios, walnuts and peanuts. The list does not include macadamias, because of their high saturated fat content.

Packages of these nuts may now bear the following line: "Scientific evidence suggests but does not prove that eating 1.5 ounces per day of most nuts as part of a diet low in saturated fat and cholesterol may reduce the risk of heart disease."

Glory be!! At least a year ago Doug Skrecky was urging Immortalist readers to eat a handful of peanuts a day as part of a heart healthy diet!!

Only packages of approved nuts can make the claim, not fat packed ice cream with a nut sprinkle, and packages must direct consumers to check the back label for full calorie and fat disclosure.

News & Views

NEVER SAY DIE

Dr. Paul Segall, a giant redwood towering in the cryonics forest, has suddenly left us. He deanimated on June 23, 2003. I don’t believe he would have preferred to be said to have died. "Never say die" was the motto he lived to the utmost.

The first cryonics meeting I attended was in 1978. There was Dr. Segall stressing the need for research funding. Shortly thereafter, the sum of $25 to perfuse a hamster in his garage was appropriated by the American Cryonics Society.

Many hamster experiments followed as Dr. Segall tinkered with the constituent ingredients of the perfusate. However, the first hundred hamsters or so could not be revived. Only a personality, which would not accept discouragement, would maintain his spirit in the face of such repeated failure. Finally, however, one of the test subjects miraculously revived. Later experiments followed on dogs and monkeys as well.

The breakthrough was a beagle named Miles. When Segall’s scientific paper on Miles was received with approval at a scientific conference, there was an explosion of worldwide publicity. For a while, Miles and Dr. Segall were international media superstars, and the development was the biggest boost for cryonics in the brief history of the movement. An interview with Phil Donahue on nationwide T.V. led to hundreds of inquiries from this one show alone.

The increased interest in cryonics-related research led to considerable source of capital from outside of the cryonics movement, which forced Dr. Segall to thereafter downplay his earlier connections with cryonics.

In 1992, Dr.Segall and others founded BioTime, Inc., a research corporation based in Berkeley, California, which is just now finding a booming business for its products. This is due in large part to Dr. Segall's worldwide travel and nonstop workaholic personality, pushing the entire research effort forward with great energy. { http://www.biotimeinc.com/ contains news of Dr Segall's demise, but no mention of his cryopreservation. - J de R}

One week Dr. Segall would be in New Zealand, the next might be Korea, and then a round of meetings with New York mortgage bankers. It has been said that money is liquid energy, and suddenly that energy was perceived as beginning to liquefy. In the process, Segall chilled and thawed more test animals than anyone else on earth. Here was a man working seven days a week, fifty-two weeks a year, to bring the precious gift of immortality through science to all of us.

In the last analysis he was a man, like John Kennedy, so full of life that even death was caught off guard. Now the cryonics torch is passed to others to carry or the progress of our noble and inevitable movement. Paul, we will not rest until we can bring you back. We’ll be immortal or die trying, and our eventual victory will be shared by you and the rest of mankind.

H. Jackson Zinn

Attorney At Law

1430 N. El Dorado Street, Stockton, CA 95202

Paul, along with Saul Kent and Curtis Henderson were the original directors of The Cryonics Society of New York. (A LOOK BACK, May-June 2003 Immortalist.) He has reportedly been suspended by Trans Time, hopefully we’ll have more information in the next issue.

Henry Hirsch added this on CryoNet:

"Much of the research I performed during my 1997-98 sabbatical at UC Berkeley was accomplished at BioTime. Paul Segall made this possible. I greatly regret his passing and, like others of the cryonics community, I hope to see him again someday."

And from Thomas Donaldson:

I've met Paul Segall and was both glad that he was working on cryopreservation and sad that he could not continue his work with Timiras, which then and now had the potential of providing a serious treatment for aging. And naturally I hope that he was suspended as well as possible.

He was also one of the early cryonicists, and his deanimation (which I hope was not his death) should really have been noticed much more. I would HOPE that those who knew of it would tell a complete story, perhaps in THE IMMORTALIST. The note by Ben Best is the first time I heard of his deanimation.

And from John Krug:

Reading the cryonet archives today, I found the sad news about Dr. Segall. I did know him from my years of association with what is now the ACS in the mid 1970's, early 1980's.... We did share some of the cultural sensibilities of the times back then. As well, I also disagreed with some of his ideas and attitudes or perhaps I was just not won over.... In any case, I admired his enthusiasm and hands on work in cryonics. I hope his many contributions are appreciated and recognized. I also hope that he was suspended albeit under the sudden and tragic circumstances. My thoughts are with his family and friends...

_______________________________

CI HAS ITS 49th AND 50th PATIENTS
Both were emergency sign-ups, patients not previously members. Although again we were able to pull things together on short notice, we must emphasize once more that usually this is not possible, and every effort should be made to sign up and get all arrangements in place long before any emergency. In these particular cases, it helped that key people in the families were already familiar with cryonics and CI. We also had especially good hospital cooperation in one case when it was needed.

One patient was washed out and perfused at the CI facility, with Dr. Pichugin in attendance; the other at a mortuary in another state. Further information may be published at a later time.

___________________________


BETTERHUMANS BIOETHICS DEBATE IN TORONTO—Aug. 29

Betterhumans will be holding an important event on Friday, August 29, 2003

called "Debating the Future: Bioethics from Science Fiction to Science Fact."

The event will feature Canada's leading bioethicist, Margaret Somerville, and controversial US bioethicist James Hughes. In debate moderated by journalist Tim Falconer, they will address life extension, cloning, nanotechnology and genetic engineering.

I think that this event will be extremely exciting and informative, and I want you to have an opportunity to attend. We are holding the event during the World Science Fiction convention, which attracts thousands of people If you are interested, please visit

http://www.betterhumans.com/Events/Debating_the_Future/ . Here you can learn more about the event and purchase tickets. If you are interested or know others who might be, you can also download information about sponsoring the event.

George Dvorsky

Deputy Editor, Betterhumans

E: george@...

ANNUAL MEETINGS

The annual meetings of the Cryonics Institute and the Immortalist Society will be held as usual on the last Sunday in September, this year falling on Sep. 28, at our headquarters--24355 Sorrentino Court, Clinton Township MI 48035. If anyone needs directions we can send them. Telephone is (586) 791-5961. E-mail is CIHQ@... .

The Cryonics Institute business meeting starts at 2 P.M. The Immortalist Society business meeting starts at around 5:30 P.M. At around 5:00 there will be a supper provided. Members and guests of members of CI and IS are welcome at both meetings. If you plan to attend, please try to remember to let us know in advance, so we will know how much food to have on hand.

Members will receive a notice by mail, with a tentative agenda. Perhaps the most important item is election of new presidents for CI and IS, since Robert Ettinger is retiring as president, although not from the board of directors of CI.

The only candidate so far for the presidency of CI is Ben Best, whom most of you know at least by reputation. A current member of our Board of Directors, he has a long history of activity in cryonics, with extensive technical knowledge and administrative experience. He is careful and prudent and always willing to listen. Ben lives in Toronto, but if elected he may relocate here; or if he does not relocate he plans to spend many week-ends here.

Robert Ettinger

-------------------------------

Is CI prepared to prevent a hostile takeover?

Robert Ettinger was recently asked on crenate what safeguards are in place at CI to prevent takeovers by some group aiming perhaps to milk the assets for personal profit, or to radically change the orientation. He replied:

"The first safeguard is that the directors are elected in staggered years, only one third in a given year. Also, the voting membership is closed a month before a membership meeting. It would be very difficult for any group to organize a coup at any one meeting.

"Next, although it is not enshrined in the by-laws, our officers and directors receive no pay and no perks of value.

"Next, all directors must be voting members with contracts and funding in place.

"Next, prospective directors receive careful scrutiny, especially those without a long term record of involvement in cryonics. Any red flags would make election unlikely. CI has a very low turnover of directors.

"Next, in case of any alarm bells, the membership have the final say, and can remove directors.

"Next, any radical change requires more than a simple majority of directors or of the membership. Finally, it only takes two directors to challenge any non-customary action, per the following article of the by-laws":

Article IX: Delay of Allegedly Improper Action

Any group comprising five percent (5%) of the voting members, or five voting members, whichever is greater, or two members of the Board of Directors, can delay any new or non-customary action by the Board or by the officers of the corporation, on the grounds that it is not justified by the corporate purposes.

Following any such petition, the Secretary shall call a meeting of the membership as soon as it is feasible. At such a meeting, a majority of the voting members present shall be sufficient to override the action, if a quorum is present. If a quorum is not present, the action shall be further delayed until a meeting is held at which a quorum is present or until a petition supporting the action signed by a majority of the voting members is presented to the Board. No action contrary to Article II shall be authorized in any event.

Robert Ettinger

IS CRYONICS CHEAPER THAN BURIAL?

Apparently it is in Tokyo, where cemetery plots are priced up to $86,000. As reported in FLORIDA TODAY the city government started taking applications for 50 newly opened spots at Aoyama Cemetery, the first such sale in 43 years. Tokyo is notorious as the world’s most costly city, and skyrocketing real estate prices have filtered down to cemetery plots.

A city official said "this is a very reasonable price, as this is a very famous cemetery, so we expect a large number of people to apply. Smaller plots start at $30,000, with a 40 square foot plot going for $86,000.

The cemetery, famed for its flowering cherry trees and proximity to exclusive neighborhoods opened in 1874. The ashes of more than 110,000 people have been interred there, including many politicians, artists and actors.

__________________________

RESEARCH NOTES

Following are notes on some of the work done by Dr. Yuri Pichugin since our last report.

In general, the work involved rat brain slices, rat heads, and rat hearts. Brains are obviously in many ways the most important. Heads allow more information about results under actual conditions for an individual patient. Hearts are useful in that we have a quick and easy criterion of viability--whether the heart beats. (Lack of beating doesn't prove anything about degree of damage, but presence of normal beating is encouraging.)

More information was gathered about relative toxicity of various vitrification mixtures (VMs), on which we are not ready to provide specifics. Progress was made. In some cases hearts showed full viability after exposure to VM and then washout.

Much of Dr. Pichugin's work involves devising techniques of manipulation of small specimens, designing and building equipment. The problems include how to introduce the VM and how to ascertain the concentration in various parts or tissues. Here is a brief description of the procedure of cryoprotectant content determination in tissues:

Pieces of weight 0.1-0.2 gm were soaked in 0.4-0.5 ml of distilled water by periodic shaking for 24 hours at 4 deg C. After centrifugation at 2,000 rpm for 10 minutes, the refractive index of the supernatant was measured at 25 deg C, allowing calculation of the concentration. In the case of the hearts, the refractometric method was applied to four different parts of the heart, and showed the hearts completely saturated with the VM.

To work with rat heads it was necessary to design and make a device to hold a syringe and introduce solutions into rat heads automatically without use of the hands. Working with rat jugular veins is difficult, since they are fine and have thin walls. Instead, a method was developed using cannulation of the superior vena cava to collect effluents from the rat heads.

The rat model is far from ideal, once we get beyond brain slices, not least because the blood-brain barrier in rats is less permeable than in most other mammals. There may be some additional work with rats, but the future work is expected to turn mainly to other models.

________________________________


BRITISH SIX FEET UNDER

John de Rivaz reported on CryoNet that Barry Albin, CI’s European Funeral Director, is to appear on British television in six 1/2 hour "reality television" programs. The series started on Tuesday 22 July 8:30pm ITV1 (networked)

________________________________

DAVE NEEDS HELP

From The Venturists:

We still have an opening for one worker at the Creekside Lodge in Arizona. We have 15 cabins & 4 lodge sleeping rooms, a dining room, Great room, two conference rooms, 34 acres of lush high desert grounds, surrounded by Federal and State lands ---- A Paradise. We are only 1 hour drive from Phoenix.

We hope to build a cryonics community in the area in a few years. You can take a hand in helping to change the world.

Great place for a single cryonicist or a cryonics couple. Drop me a line and let's talk. davidpizer@...

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BEN BEST’S 4th OF JULY WEEKEND

On the 4th of July weekend I attended the joint annual conference ("gathering") of American Mensa and Mensa Canada in St. Paul, Minnesota where I gave a presentation on cryonics. Out of 1,400 attendees roughly one-in-a-hundred (about 14) attended my presentation.

The description I submitted read:

Proponents of cryonics claim that low-temperature preservation of recently deceased persons may allow them to benefit from a future technology that has cured all disease and can rejuvenate people to a condition of everlasting youth. Ben Best will discuss recent technical advances that are making cryonics increasingly feasible. He will also address the controversy surrounding the desirability of cryonics if it proves feasible.

What they printed was:

Hear about recent technical advances that are making cryonics – low temperature preservation of recently deceased persons -- increasingly feasible. The presenter also addresses the controversy surrounding the desirability of cryonics.

Given this description and my title (CAN CRYONICS SAVE YOUR LIFE?) I would expect that the only people who would attend would be those suffering from a "premature" terminal illness -- or concerned about someone near death.

In my informal questioning of people this was the unanimous perception of the purpose of cryonics -- life extension, rejuvenation or the prospect of enduring youth was not in anyone's awareness.

It is hard to tell, but only a couple of people out of those who attended my presentation showed a serious interest. One woman may have come to heckle. She said that her San Francisco Mensa group had learned that a couple of cryonics companies had gone out of business in the last two years because of the power problems in California -- with the implication of a Chatsworth-like disaster for the patients in storage.

I decided that she might be talking about CryoSpan. I reminded her of what I had said about patients being stored in "thermos bottles" not vulnerable to short-term power loss. And I told her that I had been personally instrumental in negotiating the safe transfer of patients from CryoSpan to Alcor.

In general, I was surprised & disappointed by the lack of technophilia of those attending the conference. There was surprisingly little reference-to or interest-in computers.

The quality of the presentations was in general poor, but there were some excellent ones on sex and on game theory. There were also some quite interesting people there, but I was feeling very tired, discouraged and not inclined to spend time or energy socializing.

Instead I went to the excellent Science Museum and to the Mall of America. The Science Museum had a cryogenics demonstration with no mention of cryonics (unlike a similar demonstration I saw at the Ontario Science Centre where the presenter said that cryonics is a hoax because ice crystals destroy tissues).

Many Mensans love puzzles and intellectual games. I was inclined to indulge my introverted nerdy side and work on revisions/additions to the probability puzzles on my website – and add some comments about cryonics. For those interested the URL is:

http://www.benbest.com/science/theodds.html

Ben Best


Quickies

Model Is Victimized by his Winston ads. Raymond Leopard of Little Rock, Arkansas, is suing R.J. Reynolds Tobacco Co. saying that he experienced years of stress from appearing as the "Winston Man" in ads from 1978 to 1980. He said he didn’t know at the time that tobacco was dangerous. U. S. News & World Report

The Atmospheric Peril of Cow Burps may not be readily apparent, but cows generate significant amounts of methane, one of natures most powerful greenhouse gases—a known player in global climate change. Now researchers at the University of Nebraska think they’ve found a way to squelch the belch. In test tube studies they’ve found they could block a compound involved in methane production, turning the microbes seen inside cow stomachs toward the production of nutrients rather than gas. FLORIDA TODAY

The Funeral Industry continues to come up with new ideas for their customers. In the past we’ve reported on drive-in viewing, college logos on caskets, caskets displayed on "sets" reflecting the deceased interests and cremains being launched into outer space. Now a South Dakota company is broadcasting funerals live on the internet. Designed for those unable to attend in person, in addition to the funeral service they offer the previous days prayer service, and the post funeral graveside service, and an electronic guest book. Recordings can be viewed online for weeks after the funeral. Or they may buy a videotape or DVD of the service. Ibid

A Real Truth Machine? Researchers at the University of Pennsylvania are working on different lie detectors. One has a built in headband that measures blood flow changes in the brain. Another uses magnetic resonance imaging to snap split second images. Another researcher uses "thermal imaging" which trains a heat sensitive camera on peoples faces to measure blood flow around the eyes. Ibid


Imaginary Conversation

By Gina Miller © Copyright Gina Miller Printed with permission

Cryonic Suspension

Characters:

Nikolai1-A man who recently signed up for cryonic suspension.

Bertrand2 - A man who believes that death is inevitable.

Nikolai I signed up for cryonic suspension.

Bertrand Cryonic suspension?

Nikolai Yes, you know, after I die, they come and get me and store me in liquid nitrogen until they can bring me back to life.

Bertrand Have they brought anyone back yet?

Nikolai No.

Bertrand Then how do you know it's going to work?

Nikolai I don't, but if it doesn't work, I'll just still be dead, so I have nothing to lose. If there is a 0.1% chance that it might work, it's better than the 100% no chance of coming back that I would have if I was buried.

Bertrand That's creepy, your body floating around for who knows how long.

Nikolai Well, that's not really what I want to do. I'd rather live forever from right now, here in this lifetime. But if our lives are not able to be extended while I am alive, I'll use cryonic suspension as a back up plan.

Bertrand You won't go to heaven, I look forward to seeing my family members up there when I die!

Nikolai I hope you do see them. But, I want to live, here on earth, there are so many things I could do if I had all of the time in the world to do them.

Bertrand But what about your soul? Where is your soul when you are in that tank?

Nikolai My soul is contained within the physical construct of my brain. This is where my memories are stored, and my personality has been cultivated.

Bertrand What if your memories don't come back?

Nikolai That's a good question. What we know now about the brain, would not be enough to understand how memories work, there is a possibility that I would be rebuilt using my own DNA, but that my memories could be wiped out. This is why brain research is so important, to understand the brain would help to preserve it's contents. I hope that in the future, this will be possible.

Bertrand If you were revived without your memories, you would be like a baby, and have no understanding of the world. You would have to learn everything over again.

Nikolai That's a risk that I am willing to take. What if in the process of reanimation my memories are restored, since we haven't revived anyone, we do not know if this will happen or not. But, since I know that technology would have to be really advanced for cryonics patients to be revived, this means that there is a good possibilities that many technologies will be advanced, including restoring memories.

Bertrand What about what you would wake up to? You would have to friends or family?

Nikolai While my family members do not share my vision of the future and are not signed up I have friends that I have made through out this process that do, so they will be there.

Bertrand Yes, but what else will be there? You don't know what the world will be like, it could be an ugly future, you wouldn't know how things work, that would be scary.

Nikolai I look forward to the future. I have considered the future greatly, this is required if you are aiming for an extended life span or in my case immortality. Waking up to the future would be a great adventure.

Bertrand It could be a bad adventure!

Nikolai It could be, you are right, but tomorrow could hold a bad adventure for me too. There is no way to tell the future from a minute from now to 100 years from now.

Bertrand I don't know, when my time comes, it's my time to go. I wouldn't want to live that long anyway.

Nikolai Why not? What if tomorrow was your time to come, would you want to die?

Bertrand No, but it's not my decision. Fate decides. Everything happens for a reason.

Nikolai I understand that we need to believe that, to make sense of it all. But, as I get older I realize I never have enough time, there are never enough hours in the day. I predict that with the given lifespan, I will not have accomplished everything I want to.

Bertrand That's just more reason to appreciate the time we do have, and make the most of it.

Nikolai I can appreciate that, if I only live in this lifetime, or longer. That's a good attitude to have.

The name Nikolai is borrowed form a real man, Nikolai Fedorov (1829-1903), who began thinking about how one could be returned from death by using science. 

The name Bertrand is borrowed from a real man, Bertrand Russell (1872-1970) a British philosopher who so strongly believed that death can not be avoided he suggests acceptance.

These characters comments are strictly fiction and have no relation to words spoken by the names by which the characters have borrowed.

By Gina Miller - this document was a supplement to research paper originally written for a bioethics class taught by Dr. Tom Kerns.

© Copyright Gina Miller May 31, 2003. No reproduction or distribution of this document without the author's approval.


LIFE EXTENSION NEWS

NUTRITIONAL UPDATE:

We’ve all read reports from researchers that certain foods are good for our health, and six months down the road, another researcher comes to a different conclusion. The truth is that over the years, new information casts a new light on certain foods and drinks. And sometimes those findings are overstated, misinterpreted or even contradictory.

Red wine, tuna, blueberries, olive oil, and tea, have all had varying claims made about them in recent years. To set the record straight, and to show how health claims about food can vary, nutritionists were asked for the latest thinking about these popular items.

Blueberries

Quantity: 1 cup, raw

Calories: 81

Benefit: High in fiber and certain vitamins, may improve coordination. They’re high in anti-oxidants, shown to reduce free radicals that can contribute to heart disease, cancer and the effects of aging.

Drawback: Expensive, a pint may cost $4 or more, and benefits have mostly been shown in the lab. They also can stain teeth.

Consensus: A good food, but other foods provide similar benefits such as strawberries and spinach.

Olive oil

Quantity: 1 tablespoon

Calories: 119

Benefit: Olive oil is a monounsaturated fat and contains anti-oxidants. These fats are thought to lower a person’s LDL, or harmful cholesterol level.

Drawback: It’s still a fat, and high in calories.

Consensus: Along with canola oil, it’s better than cooking with animal fats, but don’t overdo it.

Tea

Quantity: 6 ounces

Calories: 119

Benefit: Recent studies suggest that tea can boost the immune system, and help protect the body against various forms of disease.

Drawback: Study results are mixed, and scientists are skeptical the effect, if proven, will turn out to be that strong.

Consensus: Fine in moderation, just don’t expect to be disease free.

Tuna

Quantity: 1 can, water packed (172 grams)

Calories: 220

Benefit: High in Omega 3 fats, which are good for the heart. The American Heart Association recommends eating fish twice a week.

Drawback: Certain types of fish, including tuna may store heavy metals such as mercury, and toxins such as dioxins and PCBs. These can damage your nervous system, and may contribute to heart disease.

Consensus: It’s safer from the can! Canned tuna comes from younger fish, which haven’t had a chance to store a lot of toxins. Pregnant and nursing women are often advised to limit their tuna intake.

Red Wine

Quantity: One glass (3.5 ounces)

Calories: 74

Benefit: Wine may reduce the risk of heart disease and stroke when consumed in moderation.

Drawback: Wine’s health benefits are hotly debated, and possibly outweighed by the health risks associated with alcohol consumption, which includes liver damage and automobile accidents.

Consensus: There may be better ways to improve ones health, but if used responsibly and in moderation, your doctor won’t complain.

Adapted from FLORIDA TODAY

_________________________________

BLOOD PRESSURE GUIDELINES CHANGED

The National Heart, Lung and Blood Institute redefined the upper limits for "normal" blood pressure from 130/85 millimeters of mercury to 120/80. Now, patients over the new limits are being told they need to exercise more, and eat less to keep their blood pressure in check.

Often called the "silent killer" because there are no symptoms, hypertension affects about 50 million Americans, or one in four adults. The new limits place another 45 million on alert as prehypertensives.

WHAT YOU CAN DO

  1. Follow a healthy diet high in fruits, vegetables and grains.
  2. Reduce salt and sodium in your diet.
  3. Maintain the proper weight for your height.
  4. Limit alcohol intake.
  5. Stop smoking.

________________________________

WOMAN DIED FROM BOTOX INJECTION

A 43 year old Williston, (FL.) woman had an allergic reaction to the anti-wrinkle drug Botox and died, according to autopsy results.

Donna Kulp died Jan. 24 after receiving an injection of Botox. Kulp went into cardiac arrest according to transcripts of the 911 call, and could not be revived. Kulp died from anaphylactic shock due to Botox and Lidocaine injections, according to a representative from the Medical Examiners office in Gainsville. Emergency workers give Lidocaine to people who are in cardiac arrest. She was a supervisor for telecommunications at the University of Florida, and an Avon representative.

Botox was approved in April 2002 for cosmetic purposes to smooth wrinkles on the face. Adapted from FLORIDA TODAY

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EVIDENCE SHOWS CHOLESTEROL STATINS MAY SLOW VALVE CORROSION

Thousands of Americans face the heart-valve surgery that Senator Bob Graham underwent last month, open heart surgery that is likely to dramatically increase as the population ages.

But what if a simple pill could slow the rusting of the aortic heart valve, and let patients postpone, or perhaps even avoid the surgery that is today’s only fix?

Scientists have uncovered tantalizing evidence that statins, those pills so popular to lower cholesterol, might do just that---and not through any cholesterol effect, but by an action that suggests even patients with low cholesterol might benefit.

"It’s very exciting," according to Dr. Ann Bolger of the American Heart Association, who is monitoring early research that suggests bad valves are half as likely to worsen if patients take statins.

The aortic valve shunts oxygen rich blood from the heart’s main pumping chamber to the rest of the body. It looks something like a rounded tulip, with three leaflets open and closing with each heartbeat.

But it can start to shut, causing the heart to pump harder to force blood through the narrowed opening. Eventually, patients with this "aortic stenosis" require open heart surgery to replace the faulty valve or face life threatening heart damage. Adapted from FLORIDA TODAY


Should Cryonicists Buy Defribrillators?

Raphael T. Haftka asked on CryoNet

"If I want to spend $2500 to decrease my chances of dying suddenly, is a defibrillator the best investment?"

Doug Skrecky replied:

Logon to pubmed and look up "policosanol" first. Then check out "enhanced external counterpulsation".

From Tim Freeman

I don't have any special insights into defibrillators, but:

Get your cholesterol tested, including your HDL. Exercise regularly.Form a stable relationship with someone else with similar interests and live with them; that way if one of you passes out, the other can do CPR (or maybe use the defibrillator?) and call for an ambulance.

The two of you should take a CPR course and get formal training to use the defibrillator if you get one. Learn the symptoms of heart attacks so you and your partner will know when to call the ambulance; I read once that the average delay between a heart attack and when a doctor gets involved is 4 hours, which is much more than you want.

There are probably supplements you could take.

Watch what the Digital Angel people are up to. You may soon be able to wear something that will call an ambulance for you if your heart stops beating. I know you can buy a panic button that you wear on a necklace and will make a phone call for you if you push it. If you're living alone I don't see how you're going to apply the defibrillator to yourself, so a panic button might be more effective.

There's a cheap version that you pay for once from Radio Shack and an expensive version with a subscription fee that sends people to rescue you if you don't touch your telephone once a day or so.

Adjust your diet so you aren't overweight. Don't smoke. If the heart attack is most likely to happen only after you age significantly, try to do calorie restriction to slow the aging. Don't overdo the CR; Ben Best has reported heart symptoms as a consequence of overzealous CR.

Most of the useful interventions seem to take time and effort, rather than money. I think that's because money is mostly a way to get someone else to spend time, and you can't really delegate something like this effectively. I suppose the straight answer to your question is to spend the $2500 to delegate other parts of your life (like food shopping?) so you can have time to pay attention to this other stuff.Tim Freeman

-----------------------------------------------

Hi there.

I wanted to add something to Tim Freeman's message about defibrillators.

I fully agree with the advice he gives, but I can add a piece of information that may save someone's life.

A defibrillator or AED is an excellent idea. Essentially one needs very little formal training in order to be able to operate one. The computer analyzes the person's heart rhythm, and makes the decision whether to defibrillate or not. It then instructs the user to push the button necessary to deliver the electric charge to the patient.

One of the most common causes of sudden death is a lethal arrhythmia, which is very different from a heart attack.

A sudden lethal arrhythmia such as pulseless ventricular tachycardia and ventricular fibrillation is treated immediately by administering an electric shock to the heart, effectively stopping it. Then, in principle, the heart's cells, which all inherently want to beat, will pick up the signal from the heart's pacer, to all beat at the same time again, thus producing a rhythm compatible with life. Essentially you are rebooting the heart by shutting it off, and hoping it will restart properly.

In the absence of an AED, one trick which can't hurt is to make a fist, swing your arm up in the air, and pound the mid chest with as much force as you can muster. (not repeatedly, just once or twice).This has sometimes been known to help...although you will initiate CPR too, as this person is likely unconscious, pulseless and breathless.

Obviously it is very important to develop a regimen that makes you as healthy as possible, as well as being very proactive with your medical provider to get thoroughly examined for any possible time bombs lurking inside.

I will likely be looking to purchase an AED, as I know from experience that the sooner a pulse is restored, the more likely the person is to survive.

Christine Gaspar

-------------------------------------------------

Thanks for all who replied to may query about the cost effectiveness of defibrillators. In particular, Christine Gaspar was as usual a good source of information. Some advised me to spend my money to keep my weight down, take care of my cholesterol, get married, etc. I probably should have said in my original message that I had already done all of these things. However, even though my heart is in good shape mechanically and the pipes are not clogged, I have arythmia, which increases my chances for a heart attack. After checking on the subject, I am leaning to the view that de-fibrillators are a good investment. Raphael Haftka

A google search turned up a number of suppliers and manufacturers selling new, used and refurbished units, the cheapest new model was $1285.


Are Statins Going Mainstream?

By John Bull

Regular Immortalist readers may remember references made by Doug Skrecky to the advantages of adding statins to ones life extension regimen. At that time few people had heard of statins and the principle aim was to reduce cholesterol levels and coronary heart disease..

Statins have come a long way since then… Newsweek’s July 14 issue carried an 8 page spread extolling the virtues of statins. The latest research shows that statins not only reduce cholesterol, and coronary heart disease, but may limit the progression of Multiple Sclerosis, and studies with rodents show that statins increase bone formation. If this research is validated, statins may prove a novel way to treat osteoporosis—one that actually builds bone, rather than just preventing its loss. Statins could reduce amyloid plaques in the brain, since cholesterol drives the production of amyloid. Plaques are a hallmark of Alzheimers Disease. Another study showed that statins slowed the progression of aortic valve disease by 50%.

It’s estimated that 12 to 15 million American adults take statins. And according to federal health recommendations, 21 million more should be taking statins to ward off cardiovascular disease. According to Dr. Rory Collins, of Oxford University, "statins are the new aspirin."

Should You Be Taking Statins?

Diet and exercise can reduce cholesterol, but your doctor may determine that you need drugs too. Here’s some guidelines.

  1. EVALUATE YOUR MEDICAL HISTORY Are you suffering from heart disease, or diabetes, with LDL over 130? If so, you are a candidate.
  2. COUNT YOUR RISKS How many risk for heart disease do you have? Smoking—High blood pressure---Low level of o good cholesterol---Family history of early heart disease---Age (men 45+. Women 55+)
  3. CHECK YOUR BAD CHOLESTEROL A doctor will use risk levels and LDL level to make the final call.
____________________________________________________________________________________________________________

Ted Williams Controversy Lingers

By John Bull

It’s been over a year now since Ted Williams died and was suspended by Alcor. His death touched off a firestorm of controversy between his children, John Henry Williams, who arranged William’s suspension and his sister Claudia, on one side, and their stepsister Bobby Jo Williams Ferrel, who contends her father never wanted to be frozen. Since December of last year, when Bobby Jo received $211,000 from their father’s trust, things have quieted down…somewhat.

According to reports in FLORIDA TODAY and The St Petersburg Times, one of the conditions of the payout was that Bobby Jo not comment to the press, or object to the court about the disposition of her father’s remains.

But Bobby Jo’s husband, Mark Ferrell can and is commenting. "They were stupid enough to leave me out of the settlement," he said, referring to John Henry, Claudia, Eric Abel, their attorney and the estate executor, Al Cassidy. "So I can keep fighting this, and I will."

And a few people are starting to come forward to confirm Bobby Jo’s story. Recently, on HBO’s Real Sports with Bryant Gumbel, Buzz Hamon, one of Williams’s longtime friends, said John Henry gradually shut his father off from his friends and the outside world. Hamon went on to say he spoke with Williams by phone, a month before he died. He said "I need a lawyer…. I’ve made a mistake" then there was some noise, and the phone went dead.

HBO also interviewed Ted William’s caretakers, Frank Brothers and George Carter. Brothers father was Williams longtime fishing buddy, and the younger Brothers knew the baseball great since he was a child. They all contend that it was never William’s desire to be suspended.

They further contend that the oil stained document containing Williams’s cryonic wish that John Henry produced a month after his father’s death was a forgery. The date on the document is November 2, 2000. They said they were with Williams day and night, each one spending 12 hours with their friend, while he awaited surgery for a pacemaker, and he never signed any piece of paper.

Frank Brothers said, "There’s no way that was done in that hospital room that day."

So Mark Ferrell continues the battle his wife was forced to give up, that is to have Ted Williams cremated and his ashes spread in the Florida Keys. "I am going to keep fighting this, I won’t quit, I promise."


CRYOGENIC STORAGE SEMINAR

On June 14th of this year, a Cryogenic Storage Seminar was held at the Marriott Hotel in Ontario, California. The seminar dealt with research that has been conducted on Timeship, (http://Timeship.org) a visionary structure designed by architect Stephen Valentine for long-term cryopreservation, and life extension research. The building is planned to hold over 10,000 human patients. A site for the building has not, as yet been chosen. Among those attending were Jack Nixon, a CI board member, Tim Freeman, a member of the Cryonics Institute, Alcor, and the American Cryonics Society, and Kelly Moy, an ACS Governor.

Jack Nixon’s impression:

The Timeship Project is very worthy and will provide a much sharper image for Cryonics in the future for those who would prefer a more futuristic architecturally desirable edifice while awaiting reanimation. Many family members would prefer to visit a place like Timeship to remember us, their loved ones, while we are sleeping, awaiting restoration.

Timeship presents a very positive aspect to Cryonic storage, and will bring many new converts to our cause. Timeship is much more for those that are living as well for those that will live again. The Reanimation Research Center will be the most important aspect of Timeship other than its patient storage facilities. However, protection of the patients is paramount. That is its most primary function. It will truly be a timeship for patient protection and to take patients to the future.Tim Freeman’s impression:

The seminar had several parts: First there was the talk by Valentine about TimeShip. He seems to have a good handle on how to make it stable against a lot of different threats. For instance, he takes into account floods, earthquakes, hurricanes, and lots of other environmental threats in site selection.

He has specific plans to keep trucks at a distance so a truck full of explosives can't affect the stored patients, and a separate circle of separation for cars, with suitably weak bridges to ensure that the truck that tries to park with the cars winds up in the moat.

However, I think he's wrongheaded in the psychology required to make it safe. He wants to make it look interesting and to have deep symbolic significance. I believe the patients would be safer if it was as drab and uninteresting as possible, and marketing was entirely divorced from patient storage. He thinks that storing frozen endangered species would decrease the risk from Earth First! types and that storing frozen religious leaders would decrease the risk from religious lunatics, but I think these would increase the risk, especially in the case of religions where a frozen religious leader is not properly buried. I find talk about symbolism to be particularly distressing because there's no way to evaluate the quality of the discourse; any garbage can be spoken and cannot be disproved.

Then there was a talk by Brian Wowk about how to do intermediate temperature patient storage. I think he's onto something important here. The idea is that you store the patient inside a metal can that conducts heat well, and you put the metal can inside an insulating container.

This combination effectively keeps the volume of the inside of the metal can at a uniform temperature. In the inside bottom of the metal can you put a small electric heating coil and a thermocouple. Connect a commercially available controller to the thermocouple and heating coil so it will heat the can as needed to keep the temperature high enough.

Do anything you like to the outside of the insulating container to keep its average temperature below the desired patient temperature. This arrangement makes it possible to keep each patient at a different temperature. The commercially available controllers even have a web server and Internet connection built into them, so you can control your patients' temperatures though an attractive UI from the comfort of your own office.

This is the first life-and-death network security problem I've come across.

Brian had a prototype on hand that was built from a commercially available water cooler. It was big enough to store a head. 21st Century Medicine can sell copies of these prototype units for $2000 each available immediately and versions that are engineered for long-term reliability for $2000 available 60 days from the time they are ordered.

There was further discussion of exactly how stable and efficient various configurations of this idea would be. The presentation was by a consultant cryogenic engineer. I can't recall his name right now.

Last, there was talk by Valentine again about designs for systems like this that are built from scratch. He thinks he can make one container that's good for transport, storage, and cool down. It would have the heat-conductor-in-insulator design mentioned above, with a damped-spring suspension as part of the case would make it possibly survivable if dropped a few feet. Unfortunately nobody has quantitive figures concerning the durability of vitrified brains, so the most important design constraint for the damped-spring suspension is unknown. This would seem to be a solvable problem: vitrify a dog's head, subject it to a known high acceleration, then look for shattering.

And last but not least, Kelly’s impression:

The seminar opened with the proposed future cryonics facility and lab by Stephen Valentine. Set on 350 acres with a 2 football-field diameter circular fortress bound by four balls and a cone in the center. Inside there would be 9 squares that house patients and labs.

Oddly there was such a need on behalf of the architect and others to keep the location secret that a land deal fell through due to leaks to the press while there is such an emphasis on the symbolism and bold outdoor architecture. It was my understanding that storage tanks would measure 75’x 75’…scary for the people working there! In each tank patients are suspended vertically in pods, in groups of four, to form a lattice arrangement 75'x75'.  Patients are accessed above from a platform through panels while wearing breathing gear and safety ropes.  The cost of building phase I was estimated at $7-10 mil.

Each lecture was followed by questions. Some wanted the building to be underground possibly in a missile silo. Valentine said that over time there would be too much risk from flooding.

Well I didn’t have the hutzpa to go up to the microphone and ask a question. I thought how about using the Super Colliding Superconductor around Houston, TX. Whatever happened to the old multi-hundred million-dollar project, abandoned by Congress when construction was nearly complete?

Over lunch I met with Dave Shumaker. His company based out of Florida consists of a professional team of five paramedics. They also handle the logistics of getting the patients to the storage facilities. I would recommend to the board that ACS contract with Shumaker. My impression of Mr Shumaker is that he is flexible to work with.

Brian Wowk briefly presented the advances in vitrification. He then showed a prototype of a temp controlled dewar system with alarm to alert by email when a critical temp is reached. It consisted of an aluminum canister with temp probe on the top and bottom and thermo coupler on the bottom, capable of sustaining a two degree differential.

The canister then fits into an insulator, 5 gal Rubbermaid thermos, and finally into a small dewar. Interestingly the temp is maintained until all the LN2 evaporates. These would be used during cool down, which can take weeks to months.

Last, we heard from cryogenic engineer Mike Iarocca. He explained the process involved to make dewars using LN2 more efficient and using evacuated aerogel as an insulator.


TORONTO SARS REPORT

Christine Gaspar is the President of the Cryonics Society of Canada, (CSC) she assisted in the perfusion of the recent case in Toronto, (Toronto’s first) and is an emergency room nurse on the front lines in the fight against SARS. She recently posted these reports on CryoNet.

Hi, I would like to report on the SARS situation in Toronto, if you as cryonet, and CSC readers are interested in hearing about it on this forum. I enjoy sharing SARS stories, because I don't think that there is any other cryonicist in the position to provide such information to the cryonics community. (That is uncensored, direct information, not skewed by the media or our public relations department). I think that the new reality of SARS is such that we as life extensionists can learn from it, and perhaps apply the lessons here to future biological threats.

I was told last night by one of the physicians I work with that my hospital has become THE authority on SARS in North America, as no one on this continent has had so much experience as us in battling it. We have more than 30 staff members infected, we have been treating the Toronto community at large with SARS since its onset in March, and our attempts at treating such a disease is groundbreaking and important.

The plastic barriers and hepafilters installed in our department were put in place because the nursing staff I work with (me included) filled out "unsafe work conditions" forms submitted to the Ministry of Labour in Ontario. We called the Ministry of Labour to come and inspect our workplace, as we knew that the existing barriers were completely inappropriate for containing this virus, and keeping us safe. Our management, physicians, or the CDC did not initiate this. I say this because I am very proud of how proactive and vocal our nursing staff has been in dealing with this disaster, and how instrumental they (we) have been in keeping SARS from spreading further.

The nursing profession has traditionally been suppressed and left out of the decision making process. In fact, as I stated before, "SARS Part Two", as it is affectionately being called, could have been completely avoided if the SARS taskforce had listened to our dire warnings that there were disturbing patterns emerging in the population we were serving, and flat out told us we were over-reacting, as they were issuing directives to all staff that it was ok to discontinue wearing N95 masks and other protective gear. I continue to present this information, because I strongly feel that we will have another outbreak if we do not remain absolutely vigilant. Every outbreak has started by one patient, which "got away".

The single biggest mistake that authorities made was insisting that SARS could not be diagnosed if an epidemiological link could not be established. A person could have a fever, shortness of breath, myalgia, etc, but if they could not recognize a contact with another SARS infected person, they refused to accept the possibility that that diagnosis could be made.

It has become evident that the SARS virus can survive on surfaces outside of the body for days, easily infecting people with no obvious relationship.

It has also been suggested that a building's ventilation system may possibly spread the virus between floors. We had an incident where two psychiatric patients became infected on our inpatient psych floor (7 west). There were also pockets of infection on 4 west (orthopedics), and 8 west, one of our SARS floors. Note the geographic location of these floors...all in the same wing of the hospital, perhaps sharing ventilation ducts. Also, I learned today that scientists in Alberta were able to isolate the virus in the air, suggesting the possibility that it may indeed be airborne, or be becoming an airborne virus. Two of our ICU nurses became infected, wearing protective gear, during the incubation of a patient...hence the introduction of the very expensive stryker suits ( the blue space suits in my photos).

The two individuals I reported on from the beginning...the 31 year old physician, and the 34 year old personal support worker...who have had SARS since March, remain on ventilators in our ICU...but they are finally showing real signs of improvement. Also, SARS virus is still being shed into our patients stool...weeks after the onset of symptoms...making it very difficult to establish how long the virus remains in the human body, and how long a patient remains infectious.

Initially, patients were being treated with a cocktail of broad-spectrum antibiotics, steroid anti-inflammatory drugs, and ribavarin. The ribavarin turned out to be useless, and in fact causing serious complications for the patient such as anemia. That was discontinued. We are currently using interferon, which is showing promise.

Also, I just learned last night that there will be a new study, starting shortly, which will assess the blood of health care workers such as myself who have been working with SARS, but have not become ill. The purpose of the study is to look for antibodies in our blood, to see if we have been exposed to the virus and developed immunity, as well as to explore the possibility that we can serve as potential carriers of SARS, by being "sub clinical", perhaps we were infected, developed very minor symptoms such as fatigue, headaches, etc and never knew that we were potentially infectious.

That's my SARS update for today

Christine….

Hi there. I am writing this to answer an email that Rick (Potvin) sent me. He asked for my opinion on the claim that licorice might be able to cure SARS. I also want to voice some of my thoughts about SARS, and give all of you an update about how its going in my little corner of the world. I have not heard of any SARS treatments involving licorice. We have 10 critically ill patients in our ICU, all on ventilators, all with SARS. Some of them are our own staff. Two patients died this week, one of which was a 45-year-old man, whose brother and mother also have SARS. (I think the mother died too).

I think that if our physicians believed that it was even possible to treat SARS with licorice, that they would try it. To date, 42 staff members of my hospital have come down with SARS. I think that that fact alone begrudgingly makes us the experts on how to deal with this disease. I can tell you, that even those who are expert in dealing with infectious disease are the first to state that there is far more we don't know about SARS than what we do know.

There will always be those who believe that there will be one natural substance out there that will cure all of the diseases that scare us the most. Always be wary of "cure all" solutions, as there really is no such thing.

I also want to comment on one of Rick's statements about SARS, where he ponders why the media is making such a big deal about it when the flu kills far more people. First of all, we can be immunized against influenza. SARS is a completely new disease, which has no cure, or immunization to date.

Secondly, if you are young and relatively healthy, you can feel quite confident in the knowledge that the flu probably won't kill you. With SARS, there really is no way of predicting who of us will recover, and who will die. SARS is a bigger threat than the flu for those reasons, and because there are a lot of aspects to studying SARS, which are worrisome.

There may be "super shedders", which are people who have a large viral load, and are better at spreading SARS than others. It has also been considered that there may be people with sub-clinical presentations of SARS, in which they show relatively few, if no symptoms, but are able to spread the disease easily. If these people are walking around, unknowingly spreading SARS in the community, there is no telling how many people will potentially become infected.

Then, there is a growing concern about how long the virus remains in the body. Consider this: A person becomes ill with SARS, and is hospitalized. 3 or 4 weeks go by, they get better and are discharged home. They are then placed on a 10 day home quarantine, and make follow up visits to the hospital 7 days, then 30 days post discharge for a follow up chest x ray and blood work. Is it possible that when they are discharged home, feeling somewhat better that they are still contagious? We have patients in our ICU who have been ill with SARS since late March. True, the virus may have passed and now they are suffering the organ damage brought on by the virus and the drugs used to treat it. But...they are still finding corona virus in these patients' stool.

Most of the patients who have managed to survive the SARS infection, have ongoing medical problems. Most of them have not completely recovered, and it is questionable whether or not they will end up with chronic breathing difficulties, etc. SARS, and the powerful immuno-suppressants, and anti- inflammatories used to treat it, are devastating to the entire body. Those in our ICU are on experimental treatments I have never heard of. In fact, I will try to find out what the current treatment protocol is, and report it to all of you as soon as I can. It might make for fascinating reading.

SARS is very frightening, especially to me, and my colleagues. My hospital has been gravely injured by the implications of SARS 2. We will lose a lot of staff. Some because they have become very ill, other because they feel betrayed by the SARS decision makers, who put politics ahead of the lives and safety of our staff.

Our hospital has been labelled "The SARS Hospital" in Toronto, by the press, and the community.

Our hospital has been closed to the public since May 23rd, and it will probably take another month to gradually re-open services. The emergency department where I work will be the last to open, when we are prepared to accept patients again.

Our reputation has been gravely injured. There will likely be a public inquiry, partially stemming from the two emergency nurses who went to the press to tell them that officials didn't heed the warnings of the nurses. There will likely be class action lawsuits, considering how many people have died or lost family members to this.

Anyhow, that's about it for now. I have created my own website. It's still under construction, but if you would like to see it, here's the address:

http://www.webspawner.com/users/christinegaspar/index.html

Christine


Want to be Rich and Famous?

By James Swayze

(Please refer to the printed edition for illustrations)

Well if you are a scientist or researcher in the field of or related fields of anti-aging medicine then you could very well soon be. In the tradition of the "Orteig prize,1" the $25,000 prize that Charles Lindbergh won for being the first pilot to successfully complete a transatlantic flight from the US to Europe, we now have the "Methuselah Mouse Prize2" . The MMP will be awarded for producing the longest-lived laboratory mouse by utilization of the fruits of research within the related fields of study around anti-aging medicine.

Another and more recent prize meant to promote advancements in science and technology is the $10 million "XPrize"3 for the purpose of spurring competition and interest both public and corporate for private non governmental manned space flight. The reader may well have seen the XPrize spoke of recently on national news with the story that Burt Rutan of "Voyager" fame is about to test fly his own design into space to win the XPrize. [Fig. 1 ref, 4]

Voyager flew round the world on one tank of gas, piloted by Chuck Yeager's daughter and Rutan's brother. These kinds of prize's can go a long way in promoting growth in science and industry. Raymond Orteig is indirectly responsible for a great number of leaps in early Aviation technology for having offered his prize.

An amount of money as large as $25,000 in the early part of the 20th century was a lot of money for an individual. At the time many saw it as a pathway to greater riches.

It went far beyond just the prize money itself. Fame would take the person a long way too. The fame alone was sought after by larger entities for which a sum such as $25,000 was not so great an amount of money. However, for such an entity the advertising value alone of being attached to such a prize and prize winner so publicly scrutinized would be enormous. Such free advertising would help greatly to generate sales for any company thus involved.

I cannot say if Orteig and his associates were interested in generating general public interest outside of aviation circles. Perhaps they just wished to see the feat accomplished sooner than the pace of aviation development at the time would have allowed so that transatlantic travel would soon become faster and cheaper than by ship. He no doubt knew that within aviation circles quite a lot of interest would be generated in winning the prize.

If only he had had the Internet for the availability of a cheap and highly effective way to involve the public in sharing in the growth of the prize. Who knows where that might have led? The Xprize  has had the benefit of the Internet for generating general public interest.

The creator of the Xprize, Peter Diamandis, did also wisely employ the Internet for the possibility of growing the prize by public sponsorship.

The Methuselah Mouse Prize will also have such opportunities, public interest generation and public support of the purse. Public donations will allow the MMP to possibly accrue to a considerable sum by the time it gets won. [See below for details on donating – be a part of supporting the quest for cures to aging] This humble reporter is proud to announce making his own very small donation to the MMP.

The Methuselah Mouse Prize is the brainchild of renowned scientist and anti-aging medicine researcher Aubrey de Grey. Aubrey and his colleagues can see great strides possible for the near future for the field of anti-aging medicine. In his own words Aubrey explains the impetus for the MMP.

"The prevailing view of the general public is that, despite much-publicised progress in certain areas, we still have no real chance of greatly extending human longevity within the lifetime of anyone alive today. This view may be over pessimistic. If so, the best way to correct it is to show that the longevity of a laboratory mammal can be greatly increased. This will be especially effective in raising public optimism and interest if the life-extending interventions are only implemented when the mouse has already reached an advanced age, and the prize is partly geared to encouraging such "late-onset" interventions."

The MMP is actually two prizes in one [see the website listed below for details]2. This is because there are two methods to achieve the same goal. Both have their own unique merit.

For one there will be methods to raise a mouse from birth to death within a certain regimen designed to maximize the mouse’s health and longevity over the entire life span of the mouse. Then also there will be the possibility, hopefully, of rejuvenating a mouse back to youthful health and vigor that is already aged or advanced in aging.

This relates to the eventual hoped for human factor in this research in the Fig. 3following ways. We certainly want to learn how to live from birth to death in a manner such that will maximize youthful vigor over our entire life but we also want to extend that life as long as possible.

This alone will be a wonderful legacy to leave for our collective progeny but what about those of us living now? No doubt many of us living now and faced already with advancing age would like to continue so and if possible even return to the health and vigor of our youth.

Until recently these kinds of hopes and desires resided solely within the realms of myth and science fiction. We at this magazine strongly feel that extreme in length and perpetually youthful life spans are even now within the realm of reasoned expectation through our own human efforts of invention and hard work. We intend to explore these possibilities and support the efforts of those that are hard at work turning science fiction into science fact.

Cryonics is the only method we now have to ensure that we might be able enjoy the fruits of technologies now only in the fledgling stages. However, cryonics is not yet widely accepted. As Aubrey says above people don’t see the future as applying to them. But if they could be allowed to believe that several more youthful and healthful years could be added to their lives then they could not help seeing that they themselves will be on hand to see that more of what is only fiction today is fact tomorrow.

They will then begin to see that cryonics has a better chance than they now give it and would apply for it as backup insurance against unexpected illness and death. Such insurance may well grant them passage into a future so wonderful as to be beyond expectation. We therefore invite and implore our readership to get involved. Not only that but get others involved. Tell your friends about this new and exciting opportunity to shape our future! Spread the exciting news that humanity’s oldest and deepest held dream is even now truly within our grasp!

Watch very closely the works and rhetoric of those that would pass laws to hinder life-affirming life extending research efforts. Tell your representa-tives to not allow human endeavor to be stifled by shortsightedness.

Question the efforts of those that would stifle these efforts to reach our loftiest goals and ask the question, ‘Whose power base stands to lose if humanity no longer need fear death?’ If you can please support research financially – stay informed and get involved – read our magazine for details as to which research to support.

A GREAT PLACE TO BEGIN:

Please go here to support the Methuselah Mouse Prize http://www.methuselahmouse.org

:Methuselah Foundation,  9131 Stone Garden Drive,  Lorton, VA 22079, USA

______________________________

References:

1[http://www.charleslindbergh.com/plane/orteig.asp]

2[http://www.methuselahmouse.org]

3[http://www.xprize.com/]

4[http://www.xprize.com/images/gallery/scaled_wkss1_lg.jpg]

5[http://www.centennialofflight.gov/essay/GENERAL_AVIATION/rutan/GA15G1.jpg]

6[http://www.charleslindbergh.com/images/LindberghCharlesSP41.jpg]

7[http://www.charleslindbergh.com/plane/p2.gif]

8[http://www.charleslindbergh.com/pics/air1.jpg]

9[http://www.xprize.com/images/gallery/xpart_1_lg.jpg]


Small Print:

For more information about cryonics or Cryonics Institute and how to become a member, visit our web site at http://www.cryonics.org.

We encourage readers to forward issues to friends and interested parties. Please send any suggestions or comments to Long Life by emailing John@...

Long Life would like to thank Longevity Report, Wired News, InfoBeat, The New York Times, The New Scientist, Nanodot, Slashdot, contributors to the Extropian and CryoNet mailing lists, members of the Cryonics Institute, and others, for helping provide some of the free public information used in Long Life.

(Disclaimer: CI does not necessarily encourage or advocate the use of any products or practices mentioned in its newsletter.)


--
Sincerely, John de Rivaz: 
http://John.deRivaz.com for websites including Cryonics Europe, Longevity Report, The Venturists, Porthtowan, Alec Harley Reeves - inventor, Arthur Bowker - potter, de Rivaz genealogy,  Nomad .. and more

#23 From: "John de Rivaz" <John@...>
Date: Thu Aug 7, 2003 10:44 am
Subject: Long Life 8
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Long Life: the Cryonics Institute newsletter

August 2003 -- Volume 2, Number 8

Welcome to Long Life -- the electronic newsletter of the Cryonics Institute. We're here to update you with brief cutting-edge news, updates, links, and information about the latest scientific, medical, health, anti-ageing, and social developments relevant to CI's goal of saving, preserving, and extending human life. Long Life may also include news about Cryonics Institute events and member activities and opinion. We welcome your feedback, and encourage readers to forward issues to friends and interested parties.


 
CI and general cryonics news
 
Recent activities at the Cryonics Institute have included by preparations for CI's Annual Meeting.  Though still in the planning stages, September 28th has been announced as the probable date for the members-only gathering. 
 
The meeting itself should begin formally at 2PM, and promises to be a historic occasion, since Robert Ettinger, founder and President of CI from its beginnings in 1976, is expected to step down.  Ettinger will by no means be leaving the Cryonics Institute, however, but will, if elected, stay on as a Director. 
 
Formally announcing himself as a candidate for the soon-to-be-open post of CI President is CI Director and long-time cryonics activist Ben Best.  Mr Best, who lives in Toronto, has served with distinction as President of CryoCare, as President and Secretary of the Cryonics Society of Canada, Treasurer of the Toronto branch of Mensa, and as President of the Institute of Neural Cryobiology, where he worked closely on the Hippocampal Slice Cryopreservation Project (HSCP) with Dr. Yuri Pichugin. 
 
A professional computer programmer, Mr Best is a specialist in database applications for the financial industry, and as an enthusiastic traveller and 'cryonics ambassador', he has been involved in cryonics-related organizations and organizational activities since the late 1980s, attending virtually every significant cryonics conference since then, and meeting with cryonicists in Australia, New Zealand, and Europe as well as throughout North America. If elected, he's expressed a willingness to move and live near to the Cryonics Institute facilities.
 
Regarded by many as one of the most technically knowledgable of cryonics advocates, Ben Best's scientific papers and other cryonics writings are archived online at http://www.benbest.org
 
In other CI news, there was further progress in CI's Research Department, headed by Dr. Yuri Pichugin.  More information was gathered about relative toxicity of various vitrification mixtures, and in some cases, rat hearts showed full viability after exposure to the mixtures followed by washout.
 
The Venturists are launching a new cryonics magazine, Physical Immortality, and a free copy is being bundled with the next issue of The ImmortalistThe new magazine is aimed for news stand distribution and is hoping to bring into the movement a few of those people who still do not use the Internet and rely on newstands. Although much is said about the huge numbers of people using the Internet, there are equally huge numbers who do not, and many of these could benefit from the concepts of cryonics if they could be educated away from many popularly held mis-conceptions.
 

 
General News Items

Important Note: A lot of these items are from sources designed for public consumption and contain no references or further information. It is up to readers to do their own web searches or whatever for further information.

 
Many of the stories here came from InfoBeat, an internet based news service. Unfortunately they have reduced their coverage of scientific issues, at least for the moment.
 
Undated or earlier items:
 
Progeria Gene discovered

[Boston, MA – April 16, 2003] – The Progeria Research Foundation (PRF), along with the National Institutes of Health (NIH), today announced the discovery of the gene that causes Hutchinson-Gilford Progeria Syndrome (HGPS or Progeria), a rare, fatal genetic condition characterized by an appearance of accelerated aging in children.

“Isolating the Progeria gene is a major achievement for the medical research community,” said Francis Collins, MD, PhD, director, National Human Genome Research Institute and the senior author on the report, which appears today in Nature. “The discovery not only gives hope to children and families affected by Progeria, but also may shed light on the phenomenon of aging and cardiovascular disease.”

Children with Progeria die from complications of cardiovascular disease or arteriosclerosis at an average age of 13. Researchers now believe finding the gene that causes Progeria may lead to answers surrounding the natural aging process and cardiovascular disease. Heart disease and stroke are the first and third leading causes of death in the United States, accounting for more than 40 percent of all deaths.

more on http://www.progeriaresearch.org/Press%20release.htm

[This was proposed for inclusion here by reader George C Smith -- readers are encouraged to email links for inclusion in this newsletter: John@... is where to send them. ] 
 
Networking Links
 
I am not sure as to the veracity of this story, but it is going around the Internet and can be given some slight relevance to cryonics:
 
His name was Fleming, and he was a poor Scottish farmer.
 
One day,while trying to make a living for his family, he heard a cry for help coming from a nearby bog. He dropped his tools and ran to the bog. There, mired to his waist in black muck, was a terrified boy, screaming and struggling to free himself. Farmer Fleming saved the lad from what could have been  a  slow and terrifying death.
 
The next day, a fancy carriage pulled up to the Scotsman's sparse surroundings.  An elegantly dressed nobleman stepped out and introduced himself as  the father of  the boy Farmer Fleming had saved. "I want to repay you," said the nobleman. "You saved my son's life."
 
"No, I can't accept payment for what I did," the Scottish farmer replied waving off the offer.
 
At that moment, the farmer's own son came to the door of the family "Is that your son?" the nobleman asked.    "Yes," the farmer replied proudly.     "I'll make you a deal. Let me provide him with the level of education  my own son will enjoy. If the lad is anything like his father, he'll    no doubt grow to be a man we both will be proud of."
 
And that he did.
 
Farmer Fleming's son attended the very best schools and in time, graduated from St. Mary's Hospital Medical School in London, and went onto  become known throughout the world as the noted Sir Alexander Fleming the discoverer of Penicillin.
 
Years afterward, the same nobleman's son who was saved from the bog was stricken with pneumonia. What saved his life this time?
 
Penicillin.
 
The name of the nobleman? Lord Randolph Churchill.
 
His son's name? Sir Winston Churchill.
 
The relevance to cryonics? If you tell all and sundry about it, there may be tenuous links to some valuable people who join the movement.
 
How to mummify yourself
 
Unlike other mummies around the world that were created by nature or by those who outlived them, this mummy is the body of a monk who underwent a process of self-mummification while still alive. more on http://www.channel4.com/history/microsites/B/bodies/bits/gallery.html#top
 
In Longevity Report 95 (and elsewhere) Steve Bridge writes: And yet, no one can do cryonics effectively by himself or herself. It requires specialized knowledge and skills, a team that works together, a building, and people willing to commit themselves to caring for frozen patients for decades at minimum. And you really cannot make individual decisions about your own cryonics care while the physician is filling out your death certificate. The mummification story does not negate this, but  before reading the mummification story I would not have thought that self treatment of mummification could be implemented either. Unfortunately I missed the first half of the tv programme that its web link represents, but I do recall from what I did see that the monks were perfecting this process for 1,000 years before they got it right! I do not know their motivation for such a project - it may have been in the part of the programme I missed.
 
 
4 July
 
Software can investigate suspicious deaths
 
Software engineers have programmed a computer to investigate suspicious deaths. It can help detectives distinguish between deaths caused by murder, suicide, accident or natural causes.
 
 
Stem cells enable paralysed rats to walk
 
Nerve cells derived from human embryonic stem cells and transplanted into paralysed rats have enabled the animals to walk again. The findings add to a growing number of studies that suggest embryonic stem cells could have a valuable role to play in treating spinal injuries.
 
The researchers, whose work was funded by stem cell giant Geron of Menlo Park, California, say trials on people could start in just two years.
 
 
7 July
 
Designer Materials
 
In times past, finding a material with just the right strength, elasticity, or other desirable traits involved a process of trial and error. People would "discover" a new material like steel or rubber, not "invent" it. Only after the fact would scientists figure out why that certain mixture of chemicals behaved a certain way.
 
But the burgeoning field of materials science is turning all of that on its head. Scientists can now start with a list of desired traits and design a custom material to suit--specifying the atomic structure, grain structure, and even heat treatments needed--without needing to resort to the old cycle of make, test, refine. Computers can simulate the physics of solid materials before they're made.
 
The secret behind this radical new ability is a combination of two modern trends: the availability of powerful, affordable computers; and advances over the last 50 years in the fundamental physics of solids. By plugging the equations of physics into a fast enough computer, you can see how a certain material will behave before it's ever made.
 
 
23 July
 
Another report on Ceremedix's new drug
 
(7-3-03) BOSTON, Mass. – A new pill, developed by CereMedix, a biotech startup at Northeastern University, could restore the body’s natural defenses so drastically that people might routinely live to be a healthy 120 years old, researchers say.  more on http://www.nupr.neu.edu/7-03/ceremedix.html
 
24 July
 
Wheelchair moves at the speed of thought 
 
Severely disabled people who cannot operate a motorised wheelchair may one day get their independence, thanks to a system that lets them steer a wheelchair using only their thoughts. more on http://www.newscientist.com/news/news.jsp?id=ns99993967 (their non-subscription service)
 
 
6 August
 
Biotime Report
 
Biotime Inc., the spin-off company from Trans Time, reported military interest in its products, for dealing with battlefield casualties. More on http://ww3.ics.adp.com/streetlink_data/dirBTX/sa189.pdf

Longevity Report 95

Volume 15 no 95. First published July 2003. ISSN 0964-5659

Libertarians and Cryonics Stephen W Bridge 2
Center for Responsible Nanotechnology Board of Advisors Mike Treder 8
Fly Longevity Experiments Douglas Skrecky 10
Death Denial Dr Steve Harris 16
The Consequences of Physical Immortality Bruce Klein 17
Publication Schedule Changes John de Rivaz 24

 

Small Print:

For more information about cryonics or Cryonics Institute and how to become a member, visit our web site at http://www.cryonics.org.

We encourage readers to forward issues to friends and interested parties. Please send any suggestions or comments to Long Life by emailing John@...

Long Life would like to thank Longevity Report, Wired News, InfoBeat, The New York Times, The New Scientist, Nanodot, Slashdot, contributors to the Extropian and CryoNet mailing lists, members of the Cryonics Institute, and others, for helping provide some of the free public information used in Long Life.

(Disclaimer: CI does not necessarily encourage or advocate the use of any products or practices mentioned in its newsletter.)

--
Sincerely, John de Rivaz: 
http://John.deRivaz.com for websites including Cryonics Europe, Longevity Report, The Venturists, Porthtowan, Alec Harley Reeves - inventor, Arthur Bowker - potter, de Rivaz genealogy,  Nomad .. and more

#22 From: "John de Rivaz" <John@...>
Date: Thu Jul 3, 2003 5:45 pm
Subject: Long Life 7
longevityrpt
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Long Life: the Cryonics Institute newsletter

July 2003 -- Volume 2, Number 7

Welcome to Long Life -- the electronic newsletter of the Cryonics Institute. We're here to update you with brief cutting-edge news, updates, links, and information about the latest scientific, medical, health, anti-ageing, and social developments relevant to CI's goal of saving, preserving, and extending human life. Long Life may also include news about Cryonics Institute events and member activities and opinion. We welcome your feedback, and encourage readers to forward issues to friends and interested parties.


 
CI and general cryonics news
 
In June 2003 The Cryonics Institute received its 49th and 50th human patients. Both were emergency sign-ups -- patients who were not members prior to CI being contacting to arrange suspensions. 
 
Such last-minute arrangements are usually not possible, and never ideal. To ensure a safer and better suspension, every effort should be made to sign up and get all arrangements in place long before the emergency strikes. In these two cases, it helped that key people in the families were already familiar with cryonics.
 
June was also marked, regrettably, by the death of long-time cryonics advocate and life-extension researcher, Dr. Paul Segall. Paul Segall passed away  on Monday, June 23 of an aortic aneurysm.  An early associate of Saul Kent at the Cryonics Society of New York, Paul later moved to Berkeley where he worked with Dr. Paola Timiras studying the life-extension effects of diet on mice.  He soon became associated with the cryonics organization Trans Time, and was also one of the principal figures in the biotech firm BioTime, developer of Hextend, a blood replacement product. 
 
An active cryonics advocate and supporter, Segall appeared on several television talk shows including the nationally syndicated Donohue Show, and in 1989 wrote a semi-autobiographical book LIVING LONGER, GROWING YOUNGER which details his interests in life extension and cryonics. 
 
Though details are not yet entirely confirmed, it is believed that Paul Segall was cryopreserved by Trans Time.
 
On a more positive note, the research into vitrification being led by Dr. Yuri Pichugin at the Cryonics Institute Research Lab has made marked progress. Using a special vitrification mixture, Dr. Pichugin has been able to obtain good viability of rat brain slices by the K/Na criterion, with no loss of viability after 48 hours at - 130 C.
 
June also saw the first publication of a new cryonicist journal of opinion, Physical Immortality, published by the Venturist Society.  Details should soon be available at www.venturist.org.

 
General News Items

Important Note: A lot of these items are from sources designed for public consumption and contain no references or further information. It is up to readers to do their own web searches or whatever for further information.

Undated
 
Predicting the future is notoriously difficult, and predictions about such things as telemedicine appeared in the late 1960s. For example, see the lectures on http://www.alecharleyreeves.com But news items are suggesting that the predictions made in these lectures in the late 1960s for the new millennium are coming true at last.
 
One of the main predictions that has only had limited appeal so far was that many jobs that required movement of bodies could be done more cheaply and more conveniently by telecommunication. This has in fact been scoffed at by many who cite the gregarious nature of people. It is also suggested that business trips are more popular as most people see them as more enjoyable than sitting in the office.
 
This may be set to change, according to a BBC news story first transmitted after the September 11 attacks and then repeated today on Breakfast Television with SARS cited as the main culprit..
 
While the airline industry has seen a huge drop in passenger numbers since September 11 2001's terrorist attacks, one industry has been benefiting from people's reluctance to fly.  Firms selling video conferencing equipment say they have seen a massive increase in demand.
 
More on http://news.bbc.co.uk/1/hi/business/1608424.stm including details of companies involved.
 
The UK government seems very keen on using telecommunications where movement of bodies was once the alternative. Medicine doesn't particularly spring to mind in this context, but considering that many trips to the doctor's surgery don't involve physical contact telecommunications could reduce the pressure of vehicles around medical facilities. In 1998 Prime Minister Tony Blair had personally requested information about a ground breaking new form of medical treatment which could slash waiting times for operations and consultations in rural areas.
 
 
Health Which? of June 2003 said that telemedicine could soon be in your local hospital, GP Surgery or even your own front room .... by 2004 you will be able to access information on a wide range of topics on NHS Direct digital TV.
 
More general information on this subject can be found on http://www.telemedtoday.com/
 
3 June
 
Rat Healing Raises Hope for Spinal Cure
Reuters
 
Scientists said on Monday they were closer to finding a cure for people paralyzed by spinal cord damage, following the successful healing of an adult rat.
 
Pilot trials for human patients will begin within three years, research team leader Dr Geoffrey Raisman told Reuters.
 
"This is ground-breaking evidence because it will help people with spinal cord injury who have previously had no hope of recovery," he said.
 
The trials will involve transplanting cells from other areas of the body into the spinal cord so they can provide a bridge over the spinal cord blockage and provide it with a channel to repair itself.
 
Currently there is no cure for patients who suffer spinal and brain cord injuries, which depending on the severity of injury, leaves them paralyzed, without control over their bowels, bladder, blood pressure and with no sexual function.
 
Scientists healed the injured spinal cord of a rat by growing a bridge of olfactory nerve cells across scar tissue, which acted as a guide so the severed nerve fibres were able to find their way to the right targets in the rat's brain.
 
If the human pilot trials are successful, patients will be able to make important movements like reaching for and picking things up. The restoration of other functions like bladder control require further research, Raisman said.
 
Leukaemia Drug Boosts Survival Rate by 6 Years
HealthScoutNews
 
Gleevec, hailed by many as a miracle drug against a certain type of leukaemia, allows new patients who use it to live an average of six years longer than other chemotherapy treatments, researchers say.
 
But they may live even longer than that. The research is based on a theoretical model, because Gleevec (imatinib mesylate) is so new that there aren't enough patients yet to track its effectiveness over a long period of time.
 
What the researchers do know, however, is that victims of chronic myeloid leukaemia (CML) who have used Gleevec as their primary chemotherapy have shown remarkable remission rates. The U.S. Food and Drug Administration recently gave Gleevec another approval, this time for children newly-diagnosed with CML.
 
Each year approximately 4,500 Americans are diagnosed with CML.
 
The survival model was created by a team from the Duke Clinical Research Institute and includes information from European studies. It was presented this weekend at the American Society of Clinical Oncology (ASCO) meeting.
 
'Hearing Cell' Regenerated for the First Time
HealthScoutNews
 
The cells inside the ear that actually create the sensation of hearing have been made to regenerate in mammals, and scientists say this breakthrough offers hope for millions of people who have hearing loss.
 
The Associated Press reports that the new sound-sensing cells, known as hair cells, were grown in the ears of guinea pigs by researchers from the University of Michigan. The cells were grown inside the ear's spiral-shaped chamber known as the cochlea.
 
This first-of-a-kind development could some day mean treatment for more than 30 million Americans who suffer significant loss of hearing. Scientists say that 90 percent of them have hearing loss from damaged hair cells, and until now, these cells would not regenerate on their own.
 
The cells are critical to hearing, the AP reports, because they convert sound waves into nerve impulses that go to the brain.
 
The findings are in the June 1 issue of the Journal of Neuroscience.
 
4 June
 
From Josef Hasslberger
May I inform you about a new website which I have started as a
vehicle to distribute information on health freedom and related
matters. The address:

http://www.newmediaexplorer.org/sepp/

If you have received e-mails from me in the past, you might receive
those more rarely in the future. Most of my information will be
available on that new site.

You might want to bookmark that site to check it out from time to
time, or you may also subscribe (on the top of the page - right side)
to receive e-mail alerts every time new information appears there.

The site was made possible through the help of a dear friend, Robin
Good, who is a scout for new technologies on the internet. Robin has
a site

(Sharewood Tidings -
http://www.masternewmedia.org )

and he writes a free monthly newsletter where he documents the
results of his exploration of new technologies on the net which he
shares with us - almost all of it for free. Some of his professional
reports are available for a modest price. Please visit his site. If
you're into internet activism, you might want to read his articles on
"Communication Agents".

Kind regards
Josef


--

The individual is supreme and finds its way through intuition.
Josef Hasslberger

Personal home page on physics,energy technology, social
and economic issues:
http://www.hasslberger.com
page on Ryze (a virtual networking service)
http://www.ryze.com/go/JosefHasslberger

Antiprohibition and products made from cannabis as a raw
material:
http://www.unsaccodicanapa.com

La Leva di Archimede
Association for freedom of choice:
http://www.laleva.cc

Trash Your Television!
http://www.adbusters.org/campaigns/tvturnoff/
Not satisfied with news from the tube and other controlled media?
Search the net! There are literally thousands of alternative sources
out there. Start with the following links. (But there are many more
sites with good, timely information.)
http://www.whatareweswallowing.com
http://www.whatreallyhappened.com
http://www.naturalperson.com
Robin Good's Sharewood Tidings
"Understanding comes from exploration"
http://www.masternewmedia.org
 
12 June
 
Herb extracts wrap up lethal food bugs
 
 
18:35 11 June 03 
  
Basil, one of the mainstays of Italian cuisine, might one day become a weapon in the battle against dangerous food bugs such as E. coli and listeria.
 
A new plastic food wrapper for meat and cheese which slowly oozes anti-microbial chemicals extracted from the herb has been shown to increase the food's shelf life, and should also cut the risk of food poisoning. And it does not taint the food with basil flavour, either.
 
more on http://www.newscientist.com/news/news.jsp?id=ns99993819
 
Do the living outnumber the dead?

If the world population had always been increasing at its present rate, doubling within an average human lifespan, then the living would indeed outnumber the dead.

However, this is not what has happened. There have been very long periods in the past when the population hardly grew at all, but when deaths continued to accumulate. For historical periods, there is a surprising amount of information on population figures, including censuses conducted by both the Romans and the Chinese.

On multiplying [historical and estimated] population numbers by the estimated death rates, you discover that the total number of deaths between 40 000 BC and the present comes to something in the order of 60 billion. The present world population is still less than 6 billion.

 
16 June
 
Man was 33rd oldest in the world
 
CAREY, Ohio - Linus Reinhart, one of the oldest men in the world, died Saturday 14 June 2003 in the Eaglewood Care Center here. He was 110.
 
The exact cause of death is unknown.
 
"I guess if you’re 110, something’s going to get you," said his son, Donald.
 
Mr. Reinhart was the 33rd oldest person in the world, according to the Gerontology Research Group, said the Rev. Art Young, of the Basilica of Our Lady of Consolation in Carey, where Mr. Reinhart was a member.
 
Mr. Reinhart lived in his home until he was 104, when he moved to the Eaglewood Care Center.
 
 
Acne Drug Can Prevent Paralysis Too
 
United Press International--Canadian researchers have discovered a drug used to treat acne may prevent spinal paralysis, a report said Friday. The drug, minocycline, is a common antibiotic, but University of Calgary scientists say it also limits the harmful inflammation in the spinal cord that follows an injury. Mice treated with minocycline were able to walk within days of suffering a crushing spinal injury, the National Post reported. Dr. Wee Yong and colleagues began experimenting with anti-inflammatory drugs that could be fast-tracked to human use if they proved successful. Since minocycline is already in common use in North America and has a good safety record, human trials could begin within months.
 
Can liquorice fight SARS?
HealthDay
 
A leading ingredient in liquorice has shown to be successful in fighting severe acute respiratory syndrome (SARS), at least in the lab.
 
German researchers, reporting their results in the latest issue of The Lancet, say that the compound, glycyrrhizin, was effective in stopping the SARS virus from reproducing, according to an Agence France Presse account.
 
Glycyrrhizin, which is extracted from liquorice roots, has been previously explored in antiviral research, AFP reports.
 
In this case, glycyrrhizin easily beat out four standard compounds used to block virus or tumorous cell replication -- ribavirin, 6-azauridine, pyrazofurin, and mycophenolic acid, according to the AFP report.
 
The researchers said that much more work is needed and they're nowhere near calling it a cure, but it looks promising.
 
17 June
 
Disease transmissions alarm scientists
United Press International
 
Scientists are alarmed animals are transmitting viruses, bacteria and parasites to humans more rapidly than ever before.
 
The Washington Post reported Sunday Lyme disease, Ebola, AIDS, SARS, West Nile and now, monkeypox are all zoonotic diseases, passed to humans from animals.
 
The trend of animals infecting humans is quickly gaining speed, the Post said.
 
"Influenza is a zoonotic disease. HIV is a zoonotic disease. Monkeypox. SARS," said Anthony S. Fauci, director of the National Institute of Allergy and Infectious Diseases. "You can go on and on."
 
Cholesterol Drugs Could Benefit Diabetics
World Entertainment News Network
 
Cholesterol-lowering drugs may soon be routinely prescribed to people with diabetes following the results of a major study.
 
The British Government promised to act upon the findings, which showed that more widespread use of statins would dramatically cut rates of heart disease in diabetics.
 
Elevated heart and artery disease risk is a recognised complication of diabetes. Yet currently people with the condition are not generally given statins, a class of drug that effectively reduces cholesterol.
 
Guidelines for doctors do not recommend prescribing statins to diabetic patients unless they have high cholesterol levels. But the new findings show they can benefit people with diabetes even when their cholesterol is normal.
 
Hume Cronyn Dies
Birmingham Post
 
Veteran actor Hume Cronyn, who delighted stage and screen audiences with his late wife, Jessica Tandy, has died at age 91, according to his agent's office.
 
Canadian-born Cronyn, whose career on Broadway and in Hollywood spanned more than six decades, died on Sunday.
 
He may be best known among younger moviegoers for his role in the 1980s films Cocoon and Cocoon: The Return.
 
 
Nanotube chip could hold 10 gigabits
 
 
12:47 17 June 03
 
NewScientist.com news service
 
A computer memory chip based on carbon nanotubes has passed a manufacturing milestone, according to the US company developing the technology.
 
The prototype chip would store information using hundreds of billions of nanotubes with a theoretical capacity of 10 gigabits of data, says Nantero, based in Boston, Massachusetts.
 
Once fully developed, the company says nanoscale random access memory (NRAM) could hold more data that existing types of RAM and would also be non-volatile, meaning data would not be lost when the power is been turned off. Computers using such memory could boot up almost instantly. Nantero also claims that NRAM would be much faster than current non-volatile memory, such as Flash.
 
Nantero is not the only company hoping to use carbon nanotubes to make improved types of computer memory. But the company believes its advantage lies in the fact that its chips can be made using existing silicon manufacturing methods and would therefore be relatively cheap to make.
 
 
Nantero is not quoted on any public stock market.
 
18 June
 
 
Bad breaks fixed fast by bone 'printer' 
 
19:00 18 June 03
 
Exclusive from New Scientist Print Edition
 
Shattered bones could soon be replaced by segments of artificial bone that can be "printed" within hours. The artificial bone is strong enough to bear weight, and would slowly be replaced by new bone.
 
The technique could greatly improve the treatment of bad breaks, preventing patients ending up with shorter limbs after reconstructive surgery and perhaps even saving limbs in cases where doctors might now opt for cutting them off.
 
more on http://www.newscientist.com/news/news.jsp?id=ns99993844
 
19 June
 
FDA Approves FluMist
Midnight Trader
 
The FDA tonight approved FluMist, the first influenza vaccine delivered as a nasal mist available in the U.S. for healthy people, according to a statement released from its developers.
 
FluMist will be available in physicians' offices and some pharmacies beginning in late summer to early fall, in time for this flu season.
 
The product is manufactured and marketed by MedImmune Vaccines, Inc., a wholly owned subsidiary of MedImmune, Inc. (MEDI), and is co-marketed by Wyeth Vaccines, a business unit of Wyeth Pharmaceuticals, a division of Wyeth (WYE).
 
Bipolar disorder gene discovered
 
United Press International
 
Researchers at the University of California-San Diego say they have identified the gene believed responsible for some bipolar disorders.
 
The study, published in the June 16 issue of the journal Molecular Psychiatry, indicates a mutation in a gene that regulates sensitivity to brain neurotransmitters, such as dopamine, causes bipolar disorder in as many as 10 percent of bipolar cases.
 
Researchers told Science Daily magazine they hypothesize the mutation causes an individual to become hypersensitive to dopamine, leading to the mood extremes that characterize bipolar disorder, formerly called manic-depression.
 
Two Taiwan Doctors Charged with SARS Cover-Up
Reuters
 
Two Taiwan doctors were charged on Wednesday with covering up SARS cases that allowed the deadly virus to spread unchecked through a Taipei hospital, leading to the island's first and worst outbreak.
 
Prosecutors sought an eight-year sentence for Wu Kang-wen, the former superintendent of the Taipei Municipal Ho Ping Hospital, and Lin Jung-ti, the hospital's head of infectious diseases.
 
The hospital infections in April helped turn the island into the world's third-worst hit area after China and Hong Kong, with 697 infections and 83 deaths.
 
"The investigation shows the defendants neglected their duties and failed to take necessary infection control measures, causing the deaths of several medical workers and allowing the epidemic to spread," Taipei District Court prosecutor Chen Hon-da told a news conference.
 
"Their negligence traumatizes the families of the victims, affects the country's international image and economic development," Chen said, reading the bill of indictment.
 
Gene Influences Preference for Mornings or Evenings: Study
HealthDay
 
A gene called Period 3 seems to be a factor in whether a person is at his or her best late at night or early in the morning, says a study by researchers at the University of Surrey in England, BBC News Online reports.
 
The Period 3 gene, one that's involved in regulating the body's internal clock, comes in short and long versions.
 
People with an extreme preference for evenings are more likely to have the short version of the gene, while those who strongly prefer early mornings are more likely to have the long version, the news service reports.
 
For their study, the researchers did tests on nearly 500 people. Their DNA was analyzed and the results were compared to questionnaires that asked the subjects if they were evening or morning people.
 
The findings appear in the current issue of the journal Sleep.
 
 
 
 
 
 

 

Small Print:

For more information about cryonics or Cryonics Institute and how to become a member, visit our web site at http://www.cryonics.org.

We encourage readers to forward issues to friends and interested parties. Please send any suggestions or comments to Long Life by emailing John@...

Long Life would like to thank Longevity Report, Wired News, InfoBeat, The New York Times, The New Scientist, Nanodot, Slashdot, contributors to the Extropian and CryoNet mailing lists, members of the Cryonics Institute, and others, for helping provide some of the free public information used in Long Life.

(Disclaimer: CI does not necessarily encourage or advocate the use of any products or practices mentioned in its newsletter.)

--
Sincerely, John de Rivaz: 
http://John.deRivaz.com for websites including Cryonics Europe, Longevity Report, The Venturists, Porthtowan, Alec Harley Reeves - inventor, Arthur Bowker - potter, de Rivaz genealogy,  Nomad .. and more

#21 From: "John de Rivaz" <John@...>
Date: Wed Jun 11, 2003 9:55 am
Subject: Long Life 7 - Immortalist Highlights
longevityrpt
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Long Life: the Cryonics Institute newsletter

July 2003 -- Volume 2, Number 7 - Immortalist Highlights

Welcome to Long Life -- the electronic newsletter of the Cryonics Institute. We're here to update you with brief cutting-edge news, updates, links, and information about the latest scientific, medical, health, anti-ageing, and social developments relevant to CI's goal of saving, preserving, and extending human life. Long Life may also include news about Cryonics Institute events and member activities and opinion. We welcome your feedback, and encourage readers to forward issues to friends and interested parties.

There will now be separate issues for highlights from the latest issue of The Immortalist. The reason for this is that otherwise the file is too long for some readers, and also the publication dates of The Immortalist are not synchronous with the start of each month.
 
I would also urge readers to subscribe to the paper issue of The Immortalist (see http://www.cryonics.org/info.html ) as not everything is reproduced in this email version.
 

 
From the Immortalist: 
 

Editor’s Corner…Funky Winkerbean, A Look Back, Where Are They?

News & Views…. CI Research, Another Patient, New Cryostat

Venturists Report….They Want Us

Life Extension News….3D Body Scans, 3 Healthy Moves

Meet Yvan Bozzonetti….He has an investment for us

SA’s Mobile Life Support System….A Close Up Look

Watchtower Pro Cryonics?….Jim Yount Reports

Book Review….The Philosophy of Robert Ettinger

EDITOR’S CORNER

Sometimes we forget to thank those who help get an issue out. John Besancon labels the bulk mail for each issue and brings it to the Post Office Andy Zawacki’s photos are invaluable.

Joe Kowalsky submitted the Watchtower piece, and a Funky Winkerbean comic strip with a cryonics theme. We’re not running the comic strip because the strip’s syndicate wanted $60 to put it in one issue. Maybe they glossed over the fact that we’re non-profit!

We try to get as much variety as we can in each issue, so we asked Jim Yount to reduce the Watchtower article to a more manageable size. This he did ably, the results are on page 15. John de Rivaz rose to the occasion by reviewing The Philosophy of Robert Ettinger, on page 16. So, thanks to all for a job well done!

When looking over the "A Look Back" pages, one is struck by all the unfamiliar names. What happened to these people? They joined cryonics when it was in it‘s infancy. Why didn’t they stay in for the long haul? Did they get discouraged and drop out? Are they dead and buried? Or are they presently resting in a cryostat?

The names in this issue’s "A Look Back" (CRYONICS REPORTS, February 1969,) published by The Cryonics Society of New York, are a good example. There’s a list of "Cryonics Coordinators," from different parts of the country. Of the seven names, there’s only one familiar one; Jack Nixon, currently a CI Board member. The staff of CRYONICS REPORTS didn’t fare very well either. Of the four names, only the Editor, Saul Kent is a familiar one.

So, while the cryonics movement is charging ahead, one does hope, perhaps it was the exuberance of youth that faded, and they’re still following cryonics/life extension developments.

News & Views

CI RESEARCH FORGES AHEAD

Dr. Yuri Pichugin's vitrification research continues gradually to yield new information and improved results. In recent work he has been able to keep brain slices at dry ice temperature for 48 hours, with viability as good as before cooling, namely, around 75% by the potassium/sodium criterion.

Also, two liters of the latest vitrification mixture was kept at dry ice temperature for 72 hours, with no ice crystallization.

So, according to all the results it is possible to keep a patient’s body at dry ice temperature at least for 48 hours without ice crystallization and without reduction of tissue viability.

Additional information has also been obtained pertaining to the rate of absorption of the vitrification mixture.

Work with whole animals has yet to begin.

Further information about CI's research effort, and how you can help contribute to the effort, may be found on the CI web site at: www.cryonics.org/research.html.

Cryosummit Postponed

It was revealed earlier this month on Cryonet that Alcor President Dr. Jerry Lemler has been diagnosed with cancer. The entire cryonics community met the news with great regret, all of who have noted with respect and admiration Dr. Lemler's exemplary leadership of Alcor, and many substantive contributions to the cause of cryonics.

Dr. Lemler's presence at last year's Cryosummit was one of the high points of that historic meeting. But in light of the current situation, it was felt that the need to place the burden of additional travel and discussions on Dr. Lemler and his family and associates was not warranted, and so the plans for a second Cryosummit in June of this year have been -- for the moment -- postponed.

CI, its leadership, its staff, and its members, extend to Dr. Lemler and his family our full support and our very best wishes, and we sincerely hope that Dr. Lemler has a quick, full, and speedy recovery.

________________________________

"MOST SIGNIFICANT" DISCOVERY?

The cover of the June, 2003 issue of Life Extension, magazine of the Life Extension Foundation, heralds "The Most Significant Anti-Aging Discovery in Medical History!" Subtitle is, "Research Funded by Life Extension Yields Drug That May Radically Extend Life Span."

As most of our readers already know, the Life Extension Foundation is a Florida company headed by Saul Kent and William Faloon (the latter, if I remember correctly, a former mortician). It sells vitamins and nutritional supplements. Kent and Faloon are also prime movers in 21st Century Medicine, a California company apparently with its focus now on vitrifying organs for transplant, and Critical Care Research, with applications for clinical medicine.

The drug called "most significant" is metformin. Metformin HCl is (N,N-dimethylimidodicarbonimidic diamide hydrochloride). There is considerable information about it on the web, and Life Extension wrote it up at least as early as the edition of September 2001, including recommended dosages. (www.lef.org)

The company doing the research that was funded by Life Extension Foundation is BioMarker Pharmaceuticals (www.biomarkerinc.com). Mr. Kent is Chairman of the Board of Directors. Chairman of the Scientific Adisory Board is Professor Stephen R. Spindler, U Cal Riverside.

The article discusses, among other things, the benefits of CR (caloric restriction) and the possible or probable reasons. It also says rather emphatically that CR can dramatically increase life span even when begun late in life, and holds out the same hope for metformin and related drugs. "BioMarker's research suggests it is possible that the ability of CR to extend life span in old animals occurs because it may be able to reverse aging and rejuvenate the elderly, not just slow down the aging process. If this is so, then drugs that mimic the effects of CR should be able to achieve both these objectives."

BioMarkers did not discover metformin, but has developed ways to quickly assay expression of genes so as to get a quick fix on the probable effectiveness of drugs. In general terms, this is similar to the "diagnosis on a chip" or "analysis on a chip" concept that has made waves in recent years. Being able to screen drugs at a greatly accelerated rate is indeed an important advance.

Some will be a bit discomfited by the bad fit between the brassy title of the article (written by Mr. Kent) and the content, with liberal use of "suggests" and "possible" etc. Well, we can't have everything. Mr. Kent is a salesman, and his company is in a competitive business with big claims abounding, the word "miracle" being one of the most common in the advertising of the genre. I am thankful that he and Bill Faloon have made lots of money, and directed a lot of it into both anti-aging and cryonics-related research.

Warnings: According to the LEF, metformin and similar substances should not be used by people over 80 or those with a history of kidney or liver problems, alcoholism, or congestive heart failure.

Robert Ettinger

________________________________

NEW CRYOSTAT DELIVERED

In the last issue we reported that CI had ordered a new cryostat. In the 2nd week of May it was delivered. Andy Zawacki reports that in a preliminary inspection, it "looked good"

__________________________

ANOTHER PATIENT

Cryonics Institute has its 48th human patient, this one in cooperation with the American Cryonics Society. Publication of additional information at this time has not been authorized.

________________________________

CALL FOR PAPERS (Philosophy Anthology)

Death And Anti-Death: One Hundred Years After N. F. Fedorov (1829-1903)

(Edited and Copyrighted by Charles Tandy, Ph.D.)

(Published by Universal Publishers in association with Ria University Press)

Your paper does not necessarily have to mention N. F. Fedorov. For example, your contribution may be related to the metaphysics of death or the ethics of life extension or some other theme related to death and/or anti-death. All points of view are acceptable for this volume, but your paper must be a work of quality (professional) philosophy.

Timeline:

a. NOW: Immediately email to Dr. Tandy your intent to contribute to the volume: tandy@...

b. JULY 1, 2003: Email your abstract (or first draft of paper) before this date: tandy@...

c. AUGUST 1, 2003: Email your Death and Anti-Death contribution before this date: tandy@...

About The Editor

Dr. Charles Tandy received his Ph.D. in Philosophy of Education from the University of Missouri at Columbia (USA) before becoming a Visiting Scholar in the Philosophy Department at Stanford University (USA). Presently Dr. Tandy is Associate Professor of Humanities, and Director of the Center for Interdisciplinary Philosophic Studies, at Fooyin University (Taiwan). For more information, see: http://www.doctortandy.com

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CRYOGENIC STORAGE SEMINAR

A free daylong seminar was scheduled for Saturday, June 14, on the 3rd floor of the Ontario Airport Marriott Hotel in Ontario, California. Lunch was to be provided without charge.

The seminar dealt with research that has been conducted on Timeship (http://Timeship.org), a visionary structure designed by architect Stephen Valentine for long-term cryopreservation and life extension research. The seminar was also to provide new information about intermediate temperature human storage systems by Valentine, Cryobiologist Physicist Brian Wowk and Cryogenic Engineer Michael Iarocci.

_________________________________

MY EXPERIENCE WITH SARS IN TORONTO, CANADA

Ben Best wrote this before SARS re-emerged in Toronto, and, following this, is a message he filed after the SARS reemergence.

It has been nearly a month since Toronto has had a new locally acquired case of SARS. Last week the World Health Organization removed Toronto from the list of SARS-affected areas -- following a lift of the travel advisory against non-essential travel to Toronto near the end of April.

Being a somewhat paranoid life extensionist I began wearing a facemask on the subway in early April when SARS fears were high and continued the practice for over two weeks. I never saw another person wearing a mask on the subway, but there were noticeably fewer passengers.

I work as a computer programmer for a very paranoid institution -- one of Canada's largest banks. Early in April the bank moved employees supporting the same systems to different floors in case one floor had to be quarantined.

Employees visiting different floors were to wear facemasks. Antiseptic hand cleanser was placed in the washrooms and a sign encouraged employees to wash their hands both before and after using the toilet. I began holding paper towels when opening doors.

(I believe the greatest infection risk in the washroom is from touching facilities rather than genitals -- although infection can be transferred from hands to genitals during male urination if hands are not washed first. I think the prudish concept of genitals as extra-filthy causes scrupulous hand washing in many cases in which it is unnecessary.

It would make far more sense to wash hands after each handling of money.) I have a nose that is usually dripping and itchy. I am constantly blowing and cleaning-out my nose. I never go anywhere without a handkerchief. When I am sitting alone I find it hard to go for more than a few minutes without touching my eyes, nose, mouth or hair.

Having gone for 14 years without a sick day by keeping a healthy immune system I have not had to concern myself much with infection. But I am now much more conscious of my face-touching habits and am working to combat them. Shifting from my red handkerchiefs to tissue has made me more aware of the redness of my snot. I think my excessive interest in nose-cleaning has been irritating to my mucous membranes-- not good for resisting infection.

My high intake of Vitamin E and omega-3 fatty acids reduces my vulnerability to cardiovascular clots, but it also makes my gums and nasal membranes bleed more easily. Fortunately, I am seeing less red as a result of cleaning my nose less and being gentler when I do. (I refuse to use antihistamines because of neurological side effects.)

Life is returning to normal in Toronto. The subways are jammed again during rush hour. My coworker is returning to his desk next to mine next week because it is valuable for people supporting the same systems to be together.

________________________________

Having posted an "all clear" signal earlier on CryoNet I am obliged to post a retraction. The fact that there had not been a new case since April 20th and the fact that respiratory diseases tend to decline in the summer-- and the general belief that adequate controls had been taken -- caused many in Toronto (including me) to become complacent.

To keep things in perspective, however, the new cases have been within hospitals -- and stringent quarantines are being imposed. The death toll stands at 24 out of a population of 5 million in the greater

Toronto area. So I think there is still reasonable hope that SARS in Toronto can be brought under control even within hospitals reasonably quickly.

Ben Best

And more from Ben!

The World Science Fiction Convention is being held in Toronto August 28th to September 1st: http://www.torcon3.on.ca/

I intend to have cryonics room parties and we hope to have some cryonics-related panels. I encourage those who would be interested in attending to have no fear of our fair city.

It is inevitable that virulent viral epidemics-- whether of natural origin or engineered by terrorists -- will recur and spread quickly in this world of accelerating personal mobility.

I believe that Toronto will be one of the safest cities in North America as a result of our experience -- a physical infection has produced some powerful cultural antibodies. The Toronto airport has a thermal detector now. Consciousness of the risks of infection and how to minimize them are much higher than in other cities.

And another thing about Toronto:

We have Christine Gaspar.

Ben Best

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TRANSVISION 2003 USA

Most of our readers will not read this before the conference date, however it is noteworthy that from the conference description, Transhumanist discussion is apparently becoming much more mainstream.

June 27-29, 2003

Yale University, New Haven, CT USA

 

What will the body be like in 50 years? How will changes to our bodies change our lived experience? How will we adapt the body to our needs and to the environments in which we live? Will we have conquered sickness, aging and death for all or only for the lucky few?

Will people migrate to silicon, build superbodies, or both, or neither? This conference, the first Transvision conference to be sponsored by the World Transhumanist Association in North America, will explore the future of the body from the transhumanist perspective. TV03USA is co-sponsored by the Yale Interdisciplinary Bioethics Program's Working Group on Artificial Intelligence, Nanotechnology and Transhumanism.

Transhumanism advocates the individual's right to use technology to enhance the body. This conference will begin the discussion between the transhumanist movement and the communities with which transhumanists have rarely been in dialogue: professional bioethicists, anti-technology activists, disability and transgender activists, and critical social theorists of science and technology.

The Society for Venturism is an organization dedicated to the advancing of immortalist philosophy and ideals throughout the world by being actively engaged in doing real world things. We will include all cryonicists and cryonics groups within our membership. In fact, bringing all these different organizations and people together is one of our primary goals. David Pizer, our founder, is a former Vice President of ALCOR, and yet he made a point of including both Cryonics Institute (Robert Ettinger) and ALCOR (Dr. Lemler) people on our board of directors.

The Venturist website is: www.venturist.org (www.creeksidepreserve.com is the moneymaking seed which will be the prelude to Ventureville, I am the General Manager)

John Grigg

The Society for Venturism

11255 S.S.R. 69

Mayer, Arizona 86333

It is time for all people who wish to live in a better world, which readily accepts life extension research and cryonics to band together and work to make this a concrete reality. The Society for Venturism is raising up its banners to share with the world our exciting message; aiming for the achievement of physical immortality. Our initial plans are to help our members be interviewed in the mass media, develop a major new magazine, and to have the membership advantage of sharing our beliefs from the forum of an organization that does not profit when someone gets suspended.

We will do the first aim by engaging radio and TV talk shows and offer up Venturist members to be interviewed - long and often. We hope to flood the talk shows and news shows with interviews of reasonable Venturist members who are willing to persuade others to "take the venture to the future." If you remember, we chose the word "Venturist" because a "venture" is an adventure with some risk. That is what cryonics is about.

We will spread the cryonics message by building the Venturist Magazine into a publication that can be sold in news stands and will be attractive and informative. Starting with the July 1st issue the Venturist magazine will come out every month.

Our unique organization lets others do suspensions and storage, while we concentrate on getting our message out to the world. This is so there is no perceived financial gain for us as cryonics grows. The benefits of our work will go to others.

So far we have discussed building the membership, doing radio and TV talk shows, and building the magazine and trying to get it up to standards where it can be sold in news stands. After we have progressed in this direction we can implement other benefits to immortalists like: Personal trusts to take it ($) with you; a back-up rescue option in case the patient's primary storage company gets in trouble; meetings and seminars here at the Creekside Preserve.

And in time Ventureville, our cryonics community planned for development in Mayer, will become a reality as our numbers grow. This will not happen overnight, but in time we will have houses, apartments and a lodge center to be a beacon to cryonicists everywhere who want to gather together to work on Venturist goals and also to look after each other.

People who use reason to seek their own advantage and do so without harming others, and in fact help others in the process are the most noble and honorable. And that is what you will be doing with other fine people when you join the society for Venturism. Each time the Venturists help motivate another person to sign up for cryonics, the existing cryonics population is strengthened by adding more members and the new person is helped by having the personal protection of being signed up for cryonics. Therefore, every time you help someone else through cryonics you are also helping those who are already signed up and those who are already in suspension. Working to increase membership in the cryonics movement is truly a win-win situation.

By becoming a member you will be taking part in a great undertaking which will change for the better the world we live in. Come embark on the adventure!

_____________________________________________________________________________________

Membership and Subscribers’ Query

By not only joining the Venturists but subscribing to the magazine you are showing your support to share the message of physical immortality as an attainable goal with the world.

Please enter my order for a half years’ subscription to the magazine for the second half of 2003. Enclosed you will find my payment for July through December, 2003.

USA 6 Months $12.00____

Canada 6 Months $15.00____

Overseas 6 Months $18.00____

(Take me off List ____)

Send to:

Name ______________________________________________________________

Street Address________________________________________________________

City __________________ State __________ Zip _______ Country ____________

 

 

We are trying to update our membership and subscription lists. Please help us by filling out this questionnaire and returning it to us as soon as possible. All responses will be kept strictly confidential. Thank you.

1. Full Membership Venturists Full Members must have arrangements made arrangements for cryonic suspension in the event of clinical death.

Please count me as a full member ______ .

2. Associate Member Venturist Associate members are those who are sympathetic

to cryonics, but may not have completed suspension arrangements for themselves.

Please count me as a full member ______ .

3. Subscriber I make no declarations but would like to receive the magazine.

Please count me as a subscriber only ______ .

LIFE EXTENSION NEWS

3D Body Scans are the Future

The new imaging system combines two tests you’ve probably heard of, or had before: The high tech X-rays of computerized tomography (CT) and the scans of positron-emission tomography (PET.) CT scans detect tiny abnormalities by generating cross-section pictures of the body, like pieces of bread sliced from a loaf. PET measures concentrations of subatomic particles called positrons in living tissue to create images that highlight areas of increased metabolic activity. Individually, each procedure only catches some early tumors, so patients often must have both scans separately.

The combined technologies use a single new machine to produce state-of-the-art PET and CT scans simultaneously, then fuse them into a single 3D image using a built in computer. PET-CT scans hold great potential for detecting cancers of the breast, lung, colon and lymph nodes.

PET-CT scans could help doctors determine whether a particular tumor is malignant or benign; they could also greatly reduce the number of unnecessary biopsies. Another advantage is the ability to locate with great accuracy the abnormality in question. This aids in accurate staging and planning radiation or surgery.

A PET-CT scan usually takes about 30 minutes. Approximately 45 minutes beforehand, a person is injected with a fluid that contains a low dose radioactive compound, which completely washes out of the body a few hours later. Then the patient lies on a special bed that rolls into an opening in the machine. PET-CT is painless but some people may experience claustrophobia in this confined space.

By the end of 2001, there were around 40 of these machines in operation around the country. To find one, ask your doctor to refer you to a nuclear-medicine facility; call and ask if they use the new technology. One caveat: If you get a PET-CT scan, make sure a physician trained in both radiology and nuclear medicine reads it.

 HEALTH

WIRED asked three prominent individuals if full-body scans were the last word in preventative medicine:

Dan Parker, CEO and owner, Vitascan TM

No, but full body scans will become indispensable to traditional exams. Conventional tests for heart disease-cholesterol levels, treadmills, are very poor indicators. And no one likes to endure the invasiveness of a colonoscopy. 85 percent of people currently go untested. The medical and insurance companies will soon realize that a test that costs $1000 dollars can prevent a heart attack that costs tens of thousands or cancer that can cost millions.

Suzanne Somers, patient, actress, and fitness product guru

My unbridled curiosity about what’s going on inside my body drove me to get a scan. I am happy to report that everything was normal. It’s reassuring to be able to look inside your body and check on plaque in the arteries, and on the health of vital organs. I suspect that in the future the scan will become such an integral part of being proactive about one’s health, there will be a lot more machines, which, hopefully will bring down the cost for everyone.

Ralph P. Lieto, Chair, Radiation Protection Committee, American Association of Physicians in Medicine

There are patients who get the test not because they’re displaying any symptoms or because they’re in some high-risk group, but just because they have the cash. CT scans represent significant radiation exposure. The dose you get from a mammogram is about two tenths of a rad, for a CT scan it can be 10 or 20 times greater. But technology has shown that you can run the same tests with less of a dose, so we’re leaving the door open.

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AVOIDING STROKES

While some risk factors are beyond your control-getting older, a family history of stroke, being born with a heart or blood vessel defect, the majority of strokes are preventable.

Check your cholesterol. Up to 25 percent of people age 35-55 have elevated cholesterol, a condition that increases the risk of clot induced strokes.

Keep tabs on your blood pressure. Hypertension is the number one treatable risk factor for stroke. It affects one in four adults, promotes clogging of the arteries, and puts abnormal pressure on blood vessel walls.

Feast on fruits and veggies. Population studies consistently show that people who consume three to five servings of fruits and vegetables a day significantly reduce their stroke risk.

Watch your weight. Being overweight increases the likelihood of developing high blood pressure, heart disease, and type 2 diabetes, all of which increase the risk of stroke.

Keep moving. Thirty minutes of physical activity-walking, jogging or biking three to five times a week has been shown to reduce stroke risk, in part because it stimulates the body to develop larger and more numerous blood vessels.

If you smoke, quit! Because of the adverse effects both nicotine and carbon monoxide have on the vessels, smoking doubles the risk of stroke. For smokers on the pill, stroke risk quadruples.

University of Michigan researchers have found that female stroke sufferers were 62 percent more likely to exhibit less "traditional" stroke signs than men, resulting in delayed treatment, and higher death rates. Adapted from More

Long Term Nursing Care Insurance

Long-term-care insurance is worthwhile for one group of people: those with assets of at least $300,000 over the equity in their home. Financial experts agree that generally, this insurance is a bad investment. It’s expensive too, many policies have restrictions that limit coverage, and provide limited benefits.

Consider that two thirds of all men and one third of all women age 65 and older will never spend a day inside a nursing facility Most people who do, don’t stay long. Only a minority, 25 percent of women and ten percent of men stay longer than a year. Adapted from FLORIDA TODAY Suggested Reading: Choose the Right Long Term Care, Home Care, Assisted Living and Nursing Homes. Fourth edition by Joseph L. Matthews

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Beyond Cholesterol

A blood test that measures inflammation inside blood vessel walls, C-reactive protein, is sweeping the country. Researchers have found that CRP levels may be better predictors of future risk for heart attacks or strokes, even when "bad" cholesterol-the type that clogs arteries, appears within a normal range.

CRP is a protein made by the liver that measures the presence and intensity of inflammation inside blood vessels. Doctors have been offering the test more of less routinely during the past year to heart patients where other factors such as obesity, or age, put them at high risk for a heart event.

But if a patient comes in with rheumatoid arthritis, a disease characterized by widespread inflammation, a CRP test won’t tell anything. CRP tests are highly sensitive, picking up inflammation anywhere in the body, not just inside artery walls.

Having the flu, or just stubbing your toe can make CRP readings jump dramatically. But where there are no underlying reasons for an elevated CRP and the test shows abnormalities on at least two separate readings, the patient has an increased risk of heart problems. Adapted from FLORIDA TODAY

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Three Healthy Moves

Reduce the salt.

Curbing salt intake keeps hypertension at bay. A recent study published in the New England Journal of Medicine reported that whatever a person’s salt intake was, high, medium or low; cutting back lowered blood pressure levels.

Another benefit: It may strengthen your bones by preventing calcium loss. Adults should consume no more than 2400 mg. of salt daily. On average, most of us consume about twice that.

Stock up on C.

Vitamin C may keep a cold from dragging on. Take a 500 mg. supplement once or twice daily, depending on how much you get in your diet: orange juice 82. mg per 8 ounce glass; strawberries 86. mg per cup and brussels sprout 97 mg. per cup.

Another benefit: You’ll be less likely to develop cataracts, a clouding of the eye lens, and the leading cause of vision loss in adults 55 and older.

Pop an aspirin.

Taking aspirin prevents artery clogging blood clots. Combined data from five clinical trials showed aspirin lowers the risk of heart attack and death from heart disease by 28 per cent, according to the U.S. Preventive Services Task Force.

Another benefit: A lowered risk of colon cancer. Researchers at Dartmouth Medical School studied a group of adults at high risk for colon cancer because of polyps. Those who took an 80 mg aspirin, (a baby aspirin) daily for three years, saw a nineteen percent decrease in their risk of developing colon cancer.

Talk to your doctor before starting a regimen. Adapted from FITNESS

Tea Fights Infection

A cup of tea, drank daily, could be a powerful infection fighter. Researchers report in the Proceedings of the National Academy of Science that they have found in tea a chemical that boosts the body’s defense five-fold against disease.

They said the chemical primes immune system cells to attack bacteria, viruses and fungi. Doctors at Brigham and Woman’s Hospital in Boston and Harvard Medical School announced they have isolated the chemical in the laboratory and then proved with a group of volunteers that it did protect against germs. The results gave clear proof that five cups of tea daily sharpened the body’s defenses against disease. Penny Kris-Etherton,a nutrition specialist at Pennsylvania State University, said the results add to a growing body of evidence that tea is an effective disease fighter. In the study, researchers isolated a substance called L-theanine from ordinary black tea. The substance is also found in green and oolong tea. They said L-Theanine is broken down in the liver to ethylamine, a molecule that primes the response of an immune blood cell called the gamma delta T cell.

The T cells prompt the secretion of interferon, a key part of the body’s defense against infection. They knew from previous mouse studies that boosting this part of the immune system could protect against infection.

To further test the findings, the researchers had 11 volunteers drink 5 cups a day of tea, and 10 others drink coffee. Before the test began, they drew blood samples from all 21 test subjects. After 4 weeks, they took more blood from the tea drinkers, and then exposed that blood to the bacteria called E-coli. The immune cells in those blood specimens secreted 5 times more interferon, than did blood cells from the same subjects before the weeks of tea drinking. Blood tests and bacteria challenges showed there was no change in the interferon levels of the coffee drinkers. Adapted from FLORIDA TODAY

MEET YVAN BOZZONETTI:

He’s a Postal Worker, an amateur physicist, an entrepreneur, (he has an investment opportunity for us!) and, as any Cryonet subscriber knows, a prolific poster to that forum. Yvan is an Immortalist Society member, and is planning on joining the Cryonics Institute.

I was born October 17, 1951 near Grenoble, in the southeastern part of France. As a youth, I was in poor health, so my studies were rather chaotic. Using evening courses, I managed to get two years University (official) education. I work in Paris for the French postal service. I am single. The only advantage in my work is that I can incur some debts and buy some real estate properties. I rent them and when, next year the loans will be fully repaid I'll be able to live without work.

When in Grigny, near Paris, my main hobby is reading science papers, mostly from the ArXiv server. When I can get some free time, I go back to Romans in southeast France where I have a large dusty garage full of strange tools: The biggest mirror polishing machine in the amateur astronomy world, able to work with 2 m (80") mirrors. A "pizza oven" able to cook glass plates 1 m in diameter at the critical transition temperature near 674 degree C.

Problems: The oven needs 12KW of electricity and the garage owner allows me only 3 KW. I don’t have the room to test a large mirror nor the money to buy the raw glass disk ($200,000 apiece). I have another polishing machine in the making for special materials (graphite) but I need a lathe to complete it. I have no room to put one here.

I plan on buying half an acre in an industrial area to move all that old dust to a larger building. Here I could build a large kiln to make my own 80" glass disks.

I could also use the pizza oven here to cast aluminum. I need 1,000 lbs pressure containers to test the high-pressure cryogenics hyperpolarized helium-3 technology.

I’m trying to interest a French lab working on He-3 Magnetic Resonance Imaging in the cryo version for high definition pictures (100nm). If all goes OK, a first brain scan at this resolution could be at hand 3 - 4 years from now.

At start, data processing may be a bottleneck. For the next system, using an intensity interferometer, I’ll start with light in the astronomy domain. I have been in communication with the head of the optical laboratory at The Laval University in Quebec. The next step is to use a phonon based system and have a brain scanner working at small molecule resolution., it could work with either: phaser (giga Hertz phonons) or saser (tera Hertz phonons) systems.

I am interested in these technologies because they would both: allow uploading and assess damage to be corrected by some repair system. 3 or 4 brain scanners need to be built:

1/One using magnetic resonance imaging with hyperpolarized helium-3 under pressure and low temperature. This system is slow, cumbersome and has a limited resolution in the 100 nm range. It is the simplest and only way we can derive in a short time scale the works under way in different laboratories.

2/The use of phonons (sound quasi-particles) allows a better resolution, down to the nanometer scale. Drawbacks are: Slow system, low temperature, building back pictures with four-wave interferometry (intensity interferometry). The electronics and software parts can be tested on an astronomical instrument and so, the astronomical community can contribute to the development project. The phonon part must be built separately.

3/Using entanglement produced by a narrow space between mirrors, an interferometer scanner could be built using microwaves. It would be fast, work at room temperature... and produce enormous radiation damages. Interesting to recover broken DNA from fossils and coal for example.
4/A similar system, using X-rays with quantum non-demolition technology would solve the radiation problem, this technology is 30 years from now with a vigorous R&D program. Cost may be in the billions.

Well all of that has a cost, so I plan on buying an area near a railway station to build some underground park lots. They are in dire need here and can be sold $15,000 each. I hope to make 50 of them in the coming two years, maybe not alone, if someone is interested in that project. I'll build them from pre- fabricated concrete slabs made at the Romans site. (If you need money in the coming two years, there is room for more building work, the market is 500 - 700 lots, $800 to buy the land and $2,000 in building work/park lot. 400% return on 2.5 yrs).

As you see, I plan to cease to work...

How cryonics is seen in my environment: My mother’s attitude is "why not", but she is very dubious about the possibility to recover. My uncle is quite against it and firmly for cremation. For my friends or work mates, this is at best a crazy idea.

I have some contact from time to time with Mr. J. Saby, whose mother is a patient at CI. I think the cryonics attitude in France could be improved if some authorities in the official research establishment could support it. That is one more reason to make some links with MRI researchers. Given that the current French government has slashed the research budget by 30% this year (something not seen in the past sixty years), they are in dire need to find exterior funds, if not, 90% of French labs will be closed 2 years from now. May be the car park project came just in time...

Moving? If the current projects take-off, may be in some years I'll need a small flat somewhere in the US or Canada.

Yvan Bozzonetti Azt28@...

Azt28@...

Suspended Animation’s MLSS (Mobile Life Support System)

The MLSS was developed prior to its coming to exist at Suspended Animation (SA.) It was provided SA by the Life Extension Foundation of Fort Lauderdale, who is the primary financial investor in SA. SA has modified it extensively and added features. The cart consists of several elements, including:

1. Ice Bath

2. Respiratory Integrated Thumper

3. Cardio-pulmonary bypass system for patient washout/cooling or metabolic support

4. Self contained oxygen

5. Suction system

6. Oxygen and temperature sensors

7. Storage for medical supplies

8. Battery power supply and charger

The Ice bath uses an ice/water mixture to provide efficient cooling of the patient’s skin that cannot be obtained through ice bags, due to their poor skin contact. The bath has a cutout to enable a Michigan Instruments Thumper to be positioned over the chest of the patient. A common bilge pump provides water circulation over the patient (currently being reworked). In the bottom of the bath are located copper pipes that are used to provide chill water for the bypass system described below.

The Michigan instruments push-pull Thumper provides two functions, circulation and respiration. The thumper provides five chest compressions and then sends a burst of O2 to the patient’s intubation tube for respiration. An SA added airway control valve shuts off the airway during the heart compressions, improving Thumper efficiency significantly. The Thumper is pneumatically driven using O2 from an onboard tank or air from a portable compressor.

A major benefit of the thumper is circulation of cold blood from the skin to the brain and body core. Without this blood circulation, cooling via ice/water would be significantly less effective. The thumper also ensures that medications introduced into the patient are circulated throughout the body.

Located below the ice bath is the bypass circulation system. This system consists of a calibrated roller style cardio pump, tubing, bypass reservoir, Extracorporeal Membrane Oxygenator (ECMO), heat exchanger, filters, and sensors. The system has three operating modes. In the first mode, the system pumps MHP washout fluid from an external reservoir through the ECMO (for oxygenation) and heat exchanger (cooling it to near freezing) and then through the filter/bubble trap into the patient via fem-fem bypass and finally into a waste collection bag. In this mode the unit provides body washout. In the second mode, after washout is complete, the circulation loop is closed back into the bypass reservoir so that washout fluid is passed trough the ECMO and heat exchanger into the patient and back again in a closed loop. This mode is used to cool the patient to just above the ice point. Alternatively, in a third mode, the bypass system can be used in traditional bypass mode, where blood is pumped through the ECMO for oxygenation and then back into the body for metabolic support. Cooling for the heat exchanger is provided by a SA added chill loop that pumps water from the secondary of the heat exchanger through copper tubes in the ice bath and back to the heat exchanger.

The bypass system can also be used to perfuse the body or head through the carotids in the single pass CI protocol.

Also below the ice bath is housed a complete vacuum suction system, oxygen bottles to drive the thumper and provide O2 for the ECMO, a pulse oximeter, and readouts for the multiple temperature probes in the patient and perfusion line.

The cart has dual 12 volt batteries to power the pumps and a battery charger. Storage for surgical and other supplies is also provided in the cart.

SA is in the process of further modifying the system:

1. Changing primary perfusion pump due to problems with the original unit.

2. Adding perfusion pressure and flow monitors.

3. Adding a specially designed bubble trap.

4. Adding a multi-function respiratory analyzer.

5. Adding a compressor for Thumper and ECMO support in the absence of O2.

6. Implementing a new water distribution system for patient cooling.

7. Evaluating using NITROX dive tanks rather than oxygen to support the Thumper and ECMO, due to the capacity and widespread availability of such tanks.

The MLSS is sufficiently portable to be used wherever SA can support patient transport using its ambulance or a truck dispatched from Boca Raton. However, this unit is not air transportable. SA is in the process of fabricating an air transportable unit that has most of the features of the MLSS, but is contained in boxes that can be air transported as luggage. This unit will be available in about 45 days.

We asked Dave Shumaker if they would ever consider selling these units, Dave replied "we would be very glad to fabricate these carts for sale and train persons in their use. Provision of such equipment to others has always been an element of our overall business plan."

Watchtower gives "Thumbs Up" to cryonics?

By Jim Yount

Joe Kowalsky recently called our attention to a long article in The Watchtower magazine (from 1999), written by and for the Jehovah Witnesses but without a by-line, entitled Is Everlasting Life Really Possible?. Most of the article focuses on continued life from a purely religious perspective, but attempts to show how the view of modern science supports the bible.

One of the 23 points (paragraphs) in the article discusses cryonics, then the Watch Tower writer concludes that we have this desire to live forever because the Creator intends to see that the desire is fulfilled. To quote from the article:

"10 Modern efforts to try to satisfy man's inherent desire for everlasting life are no less remarkable. A prominent example is the practice of freezing a human who succumbs to disease. This has been done in hopes of restoring life at some future time when a cure for the disease has been developed. A proponent of this practice, which is called cryonics, wrote: "If our optimism proves justified and it is learned how to cure or repair all damage-including the debilities of old age-then those who 'die' now will have an indefinitely extended life in the future.""

11 Why, you may ask, is this desire for everlasting life so embedded in our thinking? Is it because "[God] has put eternity into man's mind"? (Ecclesiastes 3:11, Revised Standard Version) This is a matter for serious reflection! Just think: Why would we have the inherent desire to live eternally-forever-if it was not our Creator's purpose that this desire be satisfied? "

The author then poses the question: "Should we trust science, and the efforts of man to give us eternal life, or trust to God?" He answers: (again quoting) :

"Really, though, human efforts have proved totally ineffective in stopping aging or in conquering death."

The author goes on to expound one of the major tenets of the Jehovah Witnesses: that earth shall be made an earthly paradise, where men shall live forever, in the flesh, under God.

Those cryonicists who are believers, might be disappointed that the author did not allow for the possibility that God would work through man to accomplish this "life everlasting." None-the-less, it is heartening that at least one Christian writer believes that there is nothing wrong with the desire to be immortal, and sees the desire fulfilled as physical immortality upon this earth, not spiritual (extra-corporal) immortality in heaven!

Any reader who wants the complete text of this article should contact John Bull by email: jbull@...

Book review: The Philosophy of Robert Ettinger, eds Charles Tandy and Scott R Stroud.

Reviewer John de Rivaz

This volume consists of a series of articles, written by different authors to the level of university standard philosophical dissertations. As I am in no way professionally qualified as a philosopher, I will have to review this book as a lay reader, and as an interested person being a signed up cryonicist. My comments are my own in this capacity, not profound philosophical remarks.

In particular, I need to ask myself whether by reading it have I learned things that I haven’t considered following regular reading of Cryonet and The Immortalist. As this review is being submitted to The Immortalist for publication I also need to ask whether the things I have learned are going to be helpful in considering whether to remain a signed up cryonicist and whether they will be helpful in discussing cryonics with other people.

It has been said elsewhere that when and if cryonics is proven to be viable, everything any cryonicist has ever written will be dissected in the minutest detail and discussed by future historians for as long as history is debated. Books discussing the points made in The Prospect of Immortality and similar works will appear in their hundreds, if not thousands. This book preceded that event, and for that reason could have been regarded as a particularly interesting glimpse into a possible future. - That is except for the fact that the majority of the articles were pessimistic or negative in their conclusions. One reasons for this could be that the articles were themselves based on classical works of philosophy from the 19th century. Some even referred to the works of Socrates, composed thousands of years in the past. This book therefore is therefore not only a product of times in which cryonic revivals have not occurred, but also times when the annihilation of the individual seemed as even more certain than the idea that daylight will return at dawn.

Whether our future is the golden future of Man into Superman or something less than ideal was the topic of many of these articles. They can be compared to writings at the dawn of the Age of Steam, before which most people (except the greatly privileged) could seldom travel more than they could walk. Today we have fragmented families and commuting times that are becoming an appreciable portion of time spent away from home in order to earn money. I wonder if anyone at the dawn of the Steam Age predicted this. They can also be compared to writings at the dawn of the computer and internet age, where the utopia of everyone working from home was proposed (for example, see <http://www.alecharleyreeves.com> for the text of learned lectures predicting this - Reeves even had digger operators working from home using remote controlled diggers by 2000). In fact, of course, this did not happen and travel delays and traffic congestion are worse (particularly by diggers driving along the highway at 20 mi/hr). Computers have also enabled legislation that makes life more complicated. But steam power, electric power, mass mobility and computers have also brought enormous benefits. Maybe the rich and privileged were better off in the past, but the vast majority of people are better off now. Most of the articles in this book appear negative about cryopreservation. Maybe because after the crash (of expectations, as much as stock quotations) of 2000, pessimism is in vogue at present.

The book starts with a foreword: Freeze-Wait-Reanimate! In which Charles Tandy gives a brief introduction to the book, its editor and subject.

The first main article is The Prisoner's Dilemma, Collective Rationality, And The Prospect Of An Indefinite Prolongation Of Life by John M. Collins. It raises some interesting points about ethics and self and group interest. The concept was introduced that if civilisation adopts policy A instead of policy B, even if A is less "ethical" than B the succeeding generation will be comprised of totally different people, therefore selecting the ethical alternative (or visa versa) would result in the total annihilation of the generation that would have followed it.

The next is Desirable And Undesirable Immortality: Ettinger And Arendt On Coping With Human Finitude by Farhang Erfani. In this article a potted history of government from kings through democracy to some post-democratic dictatorships is used as the basis to suggest that avoidance of the death of the individual is a bad idea. Although I can’t agree with the conclusion, I do feel that the article gives food for thought and I cannot fault the concept of approving the annihilation of individuals coupled with a history of government that ends with Hitler and Stalin. Brilliant! (even if the author didn’t intend it quite that way.)

Another naysaying article follows, Immortality, Death, And Our Obligations To Future Generations by Richard V. Greene. This presented cryonics as a burden on future generations. However it did not manage resolve the conundrum that "not doing something to preserve individuals’ lives" is the same as "doing something to exterminate individuals when they are no longer any productive use". From time to time governments emerge that attempt to exterminate unwanted citizens, the latest victims being the Kurds.

It seems to be a human characteristic for the rest of humanity to remove these governments sooner or later. I suspect that the same characteristic would also lead to all available cryopreserved bodies being reanimated if this is physically possible. I remain convinced that any philosophising that suggests that reanimation is an unethical burden should belong in the same class as the rationale that causes governments to eliminate unwanted individuals as a matter of general policy. But this article gives the reader a chance to work through the ideas involved, just as a reading of Mein Kampf is essential to any student of government and authority. Maybe it could be argued that the article has failed inasmuch as I have not been shaken from my previous beliefs by reading it, or maybe it is plain wrong. - Or maybe I am too thick to see the point. But if the latter applies, then there could be some advantage in not thinking too much.

Time Shock And The Problem Of Anachronistic Being: An Anthropological Approach To Cryonics by James C. Lindahl, considers the problem of continuity of self after emigration to another time. He points out that every technological advance beings benefits and problems, as I mentioned earlier. The trite answer to all of this is that "first you save your life then you worry about these issues" but nevertheless if you have the time and inclination, then this article presents several avenues for thought.

As the caring aspects of cryonics (as opposed to burning or rotting a body) have drawn people to the movement, the title Caring Cryonics? by Rita C. Manning seemed as though it would be about this. However it looked a different aspects of caring, the caring for people both financially and physically during the process of cryopreservation and possible reanimation. Male and female gender perspectives were discussed, and the effects on family units. The conclusion wasn’t particularly favourable to the concept of cryonics, but again the old issue arises - is this a valid reason for killing people by default?

The question of the nature of the individual ("The Soul") is the real subject of an article entitled Ettinger And Immortality by Scott D. O'Reilly It concludes that metaphysical ideas may show that physical cryonics is unnecessary. No compulsion anywhere, you make you own choice. No one can argue with that!

A Kantian Critique Of Cryonic Immortality by Scott R. Stroud may have philosophical merit, but I have to confess that it went right over my head!

The Anti-Death Philosophy Of N. F. Fedorov by Charles Tandy and R. Michael Perry is a version of the article that appeared in Venturist Voice and Longevity Report and probably elsewhere as well. A version can be found on <http://www.venturist.org/fyodorov.htm> It describes the pro-life philosophies of this Christian Philosopher of 19th century Russia ( whose name is spelt in Roman letters in several ways).

Immortality, Identity, And The Grounds Of Egoistic Concern by Scott D. Wilson is yet another naysaying article, based on Bernard Williams’ famous (or infamous) paper The Tedium of Immortality. What I see as fallacious is that a single person can understand everything there is to know about the universe however long he lives. The other fallacy in relation to cryonics is that cryonics doesn’t necessarily imply immortality, just indefinite (not infinite) lifespan. The very word "Immortality" is a nonsense word - you cannot know that you are immortal unless you have lived an infinite time. Infinity is unattainable by definition.

Maybe the word "immortal" is the very source of all the negativity expressed in these articles. If someone had proposed that instead of having old age pensions everyone was put in camps and gassed to death when they could no longer work I cannot seriously imagine that any of these authors would have been willing to second this proposal. Indeed if someone had suggested that all medical care beyond pain control be denied those incapable of work because of age, I cannot see any of these authors supporting the proposition. If someone aged 65 years was a victim of a "dread disease" and could be cured by medical treatment, and if so cured could possibly live to 120 years in reasonable health, should society deny him the treatment on the basis that he would be an economic burden? Again I would doubt any of these authors would promote such a dreadful idea.

Whether these "dreadful" ideas can be supported by learned and valid philosophical debate I have no doubt, presumably Hitler and his colleagues did just that. No doubt I could wade through Mein Kampf and find the arguments, but I have neither the time nor inclination. But surely the human instinct to preserve individual life stands out above all of this, rendering such arguments ultimately fallacious.

The Prospect Of Mortality: Buddhist And Heideggerian Critical Reflections On Ettinger by

Jason M. Wirth starts with comments similar to those I have made bout the actual word "Immortality". It then goes on to use concepts generated thousands of years ago by various religious philosophers as to why personal "immortality" would be undesirable. Finally 1950s anti-technology ideas were presented.

The book ends with an Afterword from Robert Ettinger, which gave some ideas from his work in progress Youniverse. There was the odd comment about some of the suggestions made by the philosophers who wrote the preceding articles, but the bulk of the material was about philosophy itself, and the various theorems and paradoxes that have occupied people’s minds down the centuries.

In conclusion I look again at the questions I asked. It may be a failing of myself rather than the book, but there is little that I hadn’t already considered about cryonics here. Despite the learned weight of some of the naysayers, they have not persuaded me that I should change my mind about being signed up for cryopreservation. As to the book being helpful, well yes, it could be helpful to some people to see the reasoning behind the many who reject cryonics. People who reject cryonics for themselves are sad, from our perspective. But those who seek to impose their rejection on others are just as worrying as anything else what threatens our lives. None of these authors said that cryonics should be withheld by violent force (which term includes force of law).

But they do tell us how people who may consider using the violent force of legislation could be justifying their actions. I wonder if Adolf Hitler and similar authors in the 1920s and 1930s had been more widely read, whether other politicians and philosophers could not have read their works and seen the dangers to come and done something about it.

This book could be a useful volume for those cryonicists looking to exactly that - see the dangers to come.

 


 

Small Print:

For more information about cryonics or Cryonics Institute and how to become a member, visit our web site at http://www.cryonics.org.

We encourage readers to forward issues to friends and interested parties. Please send any suggestions or comments to Long Life by emailing John@...

Long Life would like to thank Longevity Report, Wired News, InfoBeat, The New York Times, The New Scientist, Nanodot, Slashdot, contributors to the Extropian and CryoNet mailing lists, members of the Cryonics Institute, and others, for helping provide some of the free public information used in Long Life.

(Disclaimer: CI does not necessarily encourage or advocate the use of any products or practices mentioned in its newsletter.)

--
Sincerely, John de Rivaz: 
http://John.deRivaz.com for websites including Cryonics Europe, Longevity Report, The Venturists, Porthtowan, Alec Harley Reeves - inventor, Arthur Bowker - potter, de Rivaz genealogy,  Nomad .. and more

#20 From: "John de Rivaz" <John@...>
Date: Sun Jun 1, 2003 3:30 pm
Subject: Long Life 6
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Long Life: the Cryonics Institute newsletter

June 2003 -- Volume 2, Number 6

Welcome to Long Life -- the electronic newsletter of the Cryonics Institute. We're here to update you with brief cutting-edge news, updates, links, and information about the latest scientific, medical, health, anti-ageing, and social developments relevant to CI's goal of saving, preserving, and extending human life. Long Life may also include news about Cryonics Institute events and member activities and opinion. We welcome your feedback, and encourage readers to forward issues to friends and interested parties.


 
CI and general cryonics news
 
The Cryonics Institute, acting in co-operation with the American Cryonics Society, received its 48th human patient this month.  In addition, CI's effort to enhance its database capability took a major step forward as a new database design was created and constructed by professional database programmer and CI Director Ben Best, with the input and assistance of CI's Facilities Manager, Andy Zawacki.  Though additional data remains to be gathered and input, CI hopes the new database will allow CI to function with greater efficiency and provide improved service to its members.
 
 

 
From the Immortalist: (nothing from this bi-monthly this time)
 

General News Items

Important Note: A lot of these items are from sources designed for public consumption and contain no references or further information. It is up to readers to do their own web searches or whatever for further information.

3 May
 
Mouse egg cells made from stem cells
United Press International--Mouse stem cells for the first time have been coaxed to develop into mouse egg cells in the lab, scientists reported Thursday. Prior experiments have revealed any cell can be cloned by plugging its nucleus into an emptied egg. The ability to develop eggs from stem cells therefore offers a new way to artificially clone heart, bone and other vital cells from humans while side-stepping the ethical concerns of harvesting eggs from women donors. "We could basically have an endless source for eggs that could then be used for therapeutic cloning," lead researcher Hans Scholer, a molecular biologist at the University of Pennsylvania at Kennett Square, told United Press International.
 
6 May
 
Chemical Rejuvenates Aging Brains: Research
HealthScoutNews
 
University of Utah researchers say they've discovered a nuerochemical that seems to invigorate aging brains, reports HealthScoutNews.
 
As reported in the May 2 issue of Science, neurobiology professor Audie Leventhal and his colleagues were studying brain aging in a group of macaque monkeys, which age much like humans. The researchers found that older monkeys lost much of their ability to respond to the chemical neurotransmitter -- gamma-aminobutyric acid (abbreviated as GABA).
 
While giving GABA to young monkeys did very little in terms of improving brain function, it helped the old monkeys a lot, Leventhal says.
 
"The analogy would be a street in New York that has computer-controlled lights to regulate traffic," he says. "In an old monkey, the system doesn't work as well, because the cells respond indiscriminately to traffic patterns, so traffic comes to a standstill."
 
While the research with monkeys goes on, Leventhal says he's also started probing similar drugs that will help older human brains work better. He says the university has applied for a number of patents to cover the leading contenders.
 
(I know GABA and ageing brains was also in last month's issue, it is here to indicate it is still being reported.)
 
13 May
 
Eye Transplant Successes
World Entertainment News Network--Researchers say an eye implant designed to restore sight to the blind, is showing encouraging results in its first patient trial. Early findings one year into the trial show the artificial retina can enable a blind person to distinguish between everyday objects such as a cup or plate. Three patients have been given the device, known as an intraocular retinal prosthesis. The implant, a sliver of silicone and platinum, measures four by five millimetres and is studded with 16 electrodes. It works by electrically stimulating a patient's remaining healthy retinal cells, which in turn pass visual information to the brain.
 
Roche SARS test kit to be priced at $10-15
United Press International
 
Swiss drug firm Roche Diagnostic Monday said it expects to launch a reliable diagnostic test for severe acute respiratory syndrome, SARS, by the end of July. The test kit will be priced around $10-$15.
 
The test will be able to determine prior to the symptoms whether a person is infected with the flu-like disease, officials said.
 
As developing a new drug usually takes 8-12 years, prevention remains the best tool to fight the spread of SARS, said Franz Walt, managing director for Asia Pacific of Roche Diagnostic.
 
"We are confident that by the end of June we will have concluded this development and conducted the initial testing. By the end of July the test kits should be available to hospitals and laboratories," Walt told the Foreign Correspondent Association Monday.
 
14 May
 
British Docs Removed Thousands of Corpses' Brains Without Consent
HealthScoutNews
 
At least 20,000 brains were removed from corpses by British doctors and morticians without first getting the families' consent, says a British government report released Monday.
 
The brains were removed for research between 1970 and 1999, and that number includes only brains that are still in hospitals and universities. Many more brains may have been removed without permission and then later destroyed, the Associated Press reports.
 
A law passed in 1961 stipulated that organs could be taken from corpses without permission if there were no objections from family members. A new law passed in 1999 banned the removal of organs without family consent.
 
The government ordered an investigation after a woman learned her husband's brain had been removed without her permission in 1987.
 
15 May
 
New Molecule Helps Bones Heal Themselves
 
United Press International--New synthetic molecules could help repair bones without surgery by harnessing the body's natural healing mechanisms, an international team of scientists has reported. "You could have here a new medical application that would heal an otherwise unhealable bone," researcher David Thompson, a biologist at Pfizer Global Research and Development in Groton, Conn., told United Press International. The human skeleton can heal itself after injury, but in roughly one out of 10 cases fractured bones either heal more slowly or fail to heal at all.
 
Cold drug could yield SARS treatment
 
United Press International
 
A drug currently being tested in humans to prevent the common cold could lead to treatments for severe acute respiratory syndrome, a study released Tuesday suggests.
 
So far, scientists have not yet identified an effective medication against the SARS virus, which has spread quickly around the world infecting more than 7,000 people and causing more than 500 deaths. But the new study gives hope an effective treatment could be developed.
 
Researchers conducted molecular analysis of the SARS virus and found a drug called AG7708, which is being developed to treat the common cold, "might be a good starting point for the development of drugs against" the organism, the study's principal investigator, Rolf Hilgenfeld of the University of Luebeck, Germany, said during a teleconference from Germany.
 
16 May
 
Cancer-linked protein can make hair grow

United Press International--A protein linked to cancer also has been found to grow new hair in mice, scientists reported Wednesday. Although researchers doubt remedies for baldness are likely to emerge from these findings, by learning how hair can regenerate, they think they can use the finding to learn how the gut, breasts and other organs grow, which could improve understanding of cancers in those areas. "Any insights we have into how this pathway operates in skin may shed some light on how it works in other organ systems as well," researcher Andrzej Dlugosz, a cancer and skin biologist at the University of Michigan, told United Press International.
 
22 May
 
New Colon Cancer Drug on the Horizon
HealthScoutNews
 
A new drug that combats colon cancer by starving the tumor could be on the market within the next year. Cancer experts term the news "huge" and "historical."
 
Colon cancer patients given the drug along with chemotherapy lived at least several months longer than patients treated only with chemotherapy, reports The New York Times. The drug -- Avastin, being developed by Genentech -- prevents the formation of blood vessels that carry oxygen and nutrients to tumors. The tumors, then, don't grow.
 
Similar tumor-starving drugs have been tested before, but none successfully.
 
Health authorities caution that Avastin doesn't "cure" cancer and, in fact, may allow people with colon cancer to live only a few months longer. But, they say, with each advance, the months add up.
 
23 May
 
Psychiatric drug may thwart Alzheimer's

United Press International--A drug used for 50 years to treat manic depression could provide a one-of-a-kind, two-punch defense against Alzheimer's disease, a dementia-fomenting disorder that affects 18 million people worldwide, scientists said Wednesday. Tested in mice with a form of the neurodegenerative disease characterized by progressive senility, the drug lithium delivered crippling blows to two notable hallmarks of the ailment that ravages the brain. Researchers discovered the compound took aim at both the cell-strangling buildup of an abnormal protein called amyloid plaque and the communications-stifling jumble of malformed nerve cells called neurofibrillator tangles.
 
24 May
 

Abandoned Drug Shows Promise Against Alzheimer's
HealthScoutNews
 
Prospects of a vaccine for Alzheimer's disease in the not-too-distant future got a bit brighter today -- although they stemmed from a somewhat unlikely source.
 
Follow-up tests on the first group of people with Alzheimer's who'd received injections of an experimental vaccine -- later abandoned because of side effects -- showed what some experts describe as "remarkable" results, reports the Washington Post.
 
Of 28 people who got the shots, researchers reported steep mental declines in nine, marginal declines in 13, and stable scores or improvements in six. Further tests showed that the nine people with the worst scores had been in the control group, which did not receive the vaccine.
 
The vaccine was designed to trigger the immune system to attack and remove protein deposits, known as amyloid plaques, that experts believe are somehow related to the disease. The vaccine was pulled from testing about 15 months ago because 18 of the 300 people who got injections developed brain inflammation, the Post says.
 
But researchers working to solve the mysteries of Alzheimer's -- which causes progressive memory loss and dementia -- say the results revealed today in the journal Neuron validate the concept of a vaccine and predict one will be available within five years.
 
27 May
 
RNA therapy against three brain diseases

AP United Press International
 
A new but still experimental therapy has neutralized Lou Gehrig's disease and two other brain-scrambling disorders in lab-grown human cells, two teams of scientists have discovered.
 
Medical experts said this advance reveals how potentially revolutionary the new genetic technique known as RNA interference could be against such major diseases as Alzheimer's and Parkinson's, and perhaps even cancer and AIDS.
 
"As a neurologist who sees people suffering from these devastating illnesses, I consider it a major impact if we could target these incurable diseases," Henry Paulson, the first team's lead researcher and a neuroscientist at the University of Iowa, told United Press International.
 
[This says so little that I hesitate to include it, but it may be of use to someone.]
 
28 May
 
Families Could Be Shut Out of Organ Donor Process

HealthScoutNews--Organ transplant advocates want to streamline the donation process by removing a donor's family from the approval process. Now, in most states, a medical official tells a prospective donor's family what the person's wishes were, based on what he or she indicated on a donor card. But the family has the final say. The new method would let doctors harvest someone's organs based solely on the donor authorization form, with the family informed about what would happen but not asked for approval, reports the Associated Press. Such a change would require a change in laws in most states to make clear that a donor card, which includes a driver's license, is legal authorization for donation.  
 
With Doctors, Will You Pay for What You Get?

HealthScoutNews
 
Need your doctor to call in a prescription refill? Or sign a form so your kid can go to camp?
 
Such requests could cost you, reports The Washington Post.
 
A still small but growing number of doctors have started charging patients for the administrative tasks that medical offices traditionally have handled for free, considered part of their cost of doing business. Some doctors itemize the charges -- a certain amount for a phone or e-mail conversation with patients or their relatives, a different amount for copying medical records or sending records to a specialist, for instance. Others are opting for a flat surcharge, sometimes called an annual administrative fee.
 
Whatever the method, the aim is to recoup what doctors say are the ever-growing costs of doing business, which reportedly have increased about 60 percent in the past decade. Doctors most likely to add such fees, says The Post, are those in internal medicine, pediatrics, and family practice -- considered the most patient-intensive and the least profitable specialties.
 
The culprits, say health-care experts, are the combination of rising overhead and declining reimbursements from insurance companies and the federal government, as well as fewer patient visits but more patient demands for services.
 
31 May
 
High Anxiety May Lead to High Cancer Risk
HealthScoutNews
 
A new study from Norway suggests people who worry too much may put themselves at increased risk for cancer.
 
The controversial finding should stoke the debate on whether psychological factors may play a role in the development of cancer, says a report in Wednesday's BBC News Online. Scientists are divided on the issue, with most saying there is not enough evidence to link stress, depression or anxiety to the disease.
 
In this latest research, scientists from the University of Bergen followed up on 62,591 people who had taken part in a medical survey between 1995 and 1997. The survey was originally used to draw up a national cancer register in Norway.
 
Those in the study also took a test to determine if they suffered from anxiety. The researchers found the people who scored high in this test were 25 percent more likely to have abnormal cells. However, because of the large number of people involved they couldn't say whether anxiety was actually a major risk factor for cancer. Also, the survey did not provide information on whether people smoked or led unhealthy lifestyles, which also increase the chances of developing the disease.
 
Comment
I have for a long time conjectured that the procedures of medical diagnosis and treatment generate unnecessary anxiety because of delays and lack of information to the patients. The reason for such delays are often economic necessity, especially in health systems funded from general taxation rather than individual insurance. If it can be demonstrated scientifically that the extra stress results in extra physical illness that costs money to treat, there could be sound economic arguments for change.
 
 
 

 

Small Print:

For more information about cryonics or Cryonics Institute and how to become a member, visit our web site at http://www.cryonics.org.

We encourage readers to forward issues to friends and interested parties. Please send any suggestions or comments to Long Life by emailing John@...

Long Life would like to thank Longevity Report, Wired News, InfoBeat, The New York Times, The New Scientist, Nanodot, Slashdot, contributors to the Extropian and CryoNet mailing lists, members of the Cryonics Institute, and others, for helping provide some of the free public information used in Long Life.

(Disclaimer: CI does not necessarily encourage or advocate the use of any products or practices mentioned in its newsletter.)

--
Sincerely, John de Rivaz: 
http://John.deRivaz.com for websites including Cryonics Europe, Longevity Report, The Venturists, Porthtowan, Alec Harley Reeves - inventor, Arthur Bowker - potter, de Rivaz genealogy,  Nomad .. and more

#19 From: "John de Rivaz" <John@...>
Date: Thu May 1, 2003 3:32 pm
Subject: Long Life 5
longevityrpt
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Long Life: the Cryonics Institute newsletter

May 2003 -- Volume 2, Number 5

Welcome to Long Life -- the electronic newsletter of the Cryonics Institute. We're here to update you with brief cutting-edge news, updates, links, and information about the latest scientific, medical, health, anti-ageing, and social developments relevant to CI's goal of saving, preserving, and extending human life. Long Life may also include news about Cryonics Institute events and member activities and opinion. We welcome your feedback, and encourage readers to forward issues to friends and interested parties.


 
CI and general cryonics news
 
CI Research Forges Ahead
 
Dr. Yuri Pichugin's vitrification research continues to progress, although for patent-related reasons CI cannot provide details immediately at this time. However, we can say definitely that Dr. Pichugin has devised solutions that do vitrify at reasonably slow cooling rates.  And also that, when applied to rat brain slices, the new solutions result in good viability, though not yet perfect, after exposure to cryogenic temperatures, as measured by the K/Na criterion.
 
There will be a natural progression from rat brain slices, to whole animals and larger animals, to human cadavers supplied for use in biological research.  Results after rewarming will be verified by several different criteria. CI hopes to be able to use the new solutions and procedures for improved care for CI patients within the year.
 
Further information about CI's research effort, and how you can help contribute to the effort,  may be found on the CI web site at www.cryonics.org/research.html.
 
Cryosummit Postponed
 
It was revealed earlier this month on Cryonet that Alcor President Dr. Jerry Lemler has been diagnosed with cancer.  The news was met with great regret by the entire cryonics community, all of whom have noted with respect and admiration Dr. Lemler's exemplary leadership of Alcor, and his fine work and many substantive contributions to the cause of cryonics. 
 
Dr. Lemler's presence at last year's Cryosummit was one of the high points of that historic meeting.  But in light of the current situation, it was felt that the need to place the burden of additional travel and discussions on Dr. Lemler and his family and associates was not warranted, and so the plans for a second Cryosummit in June of this year have been -- for the moment -- postponed.
 
CI, its leadership, its staff, and its members, extend to Dr. Lemler and his family our full support and our very best wishes, and we sincerely hope that Dr. Lemler has a quick, full, and speedy recovery.
 

 
From the Immortalist: 
 

NEWS & VIEWS

Update From Suspended Animation

This is the first of what we hope will many updates from Suspended Animation, Inc. over the next six months or so.

Suspended Animation, Inc (SA) got operationally underway in February of 2002 on a nine-day standby, transport, and vitrification effort in conjunction with Alcor. Significant capital infusion arrived in May, 2002. We were only able to move into a facility in November. Immediately thereafter we moved our equipment from Rancho Cucamonga, only to put much of it in storage to make room for the facility build out. Only one municipality in all of south Florida would permit our animal research activities. Finding a similarly friendly landlord in that one small town proved difficult. Fortunately for us the facility is within about two miles of the Florida Atlantic University, which has just welcomed its first freshman medical school class this past month. Our address is:

Suspended Animation, Inc.

1082 South Rogers Circle

Boca Raton, FL 33487

Phone: (954) 997-4062 (primary and emergency),

David Hayes cell phone is (561) 703-2388

David Shumaker cell is (954) 557-8760 and his home is (941) 743-9584

We are at: www.suspendedanimationinc.com (crude that it is)

Since our beginning, we have been busy with patients. We have participated in three standby/recovery/transports followed by patient neuro vitrification / whole body freeze and three standbys that were terminated with patient survival. One case was groundbreaking, with the patient stored at intermediate temperature after vitrification. All of these activities have been made possible by Alcor who has enabled us to work on cases that we could not have done by ourselves due to our lack of facilities.

As many already know, Mike Darwin quit last July, leaving us at a critical moment. After a somewhat trying period following Mike's departure, SA completely released him from his employment contract. Significantly, four of our patient activities occurred after Mike quit. In fact, Dave Hayes, our COO, is clearly one of the most experienced per sons in standby/transport of those now active. While Mike had an immense amount of experience that we will miss, his departure in some ways opens the door for a new generation of cryonics personnel.

In November of 2002 we hired Mike Quinn, a 25 year veteran of animal research and emergency response medicine. Chris Dougherty, PhD (Molecular & Cellular Pharmacology), who has been doing research on ischemic and reperfusion damage to cardiac tissue, starts work with us this month. Together Chris and Mike will lead our future research. We are interviewing additional medical and technician personnel for our staff. If you know of someone, please get in touch with us. We anticipate being able to provide high quality standby and transport for anyone within about 90 days. Patient cryopreservation at our facility is still at least 4-7 months away, depending upon how fast we can assemble and train personnel and fabricate equipment.

While we have been involved only with Alcor patients during our first year, SA wants to emphasize that it is dedicated to providing cryopreservation services ecumenically. As promised from the beginning, our services and our technology will always be available to serve anyone, irrespective of organizational association. We are equally anxious to pursue developments in conjunction with others. We were engaged with Alcor because Alcor, their patients, and facilities provided us an opportunity to perform work, where otherwise we could not. have. These efforts have provided us a jump start in learning critical details of the overall cryopreservation process that will help us support the entire community earlier than we would have been able to do otherwise.



Thanks to Dave Shumaker for the SAI update.
Concerning relations among CI, its members, and SAI or others, our aim is to allow the widest range of options to our members, including preparation elsewhere and storage at CI, or vice versa, if the member perceives a rationale for the strategy. Such division of responsibilities has, in fact, occurred more than once.

Concerning research strategies--sharing of plans, information, and benefits--that is a much more difficult area and likely to bog down in legal or administrative quicksand.

There is added complication in that SAI, TransTime, 21CM, and Cryospan are organized for profit, while CI, ACS, and Alcor are nonprofit. However, we are always open to suggestions, and we will always keep in mind the needs of members of all organizations.

Robert Ettinger



.

UPDATE FROM SUSPENDED ANIMATION March 30, 2003

Suspended Animation continues to develop its facilities in Boca Raton, FL, while it provides limited services to patients. Over the past month, SA performed a patient Standby and Transport in Florida under a last minute direct contract with the patient’s son. The son made separate last minute arrangements with CI for cooldown and long term custodial care.

In this case, SA was bedside when the patient died late at night and was able to immediately initiate medication, CPS, transfer into SA’s portable ice bath, and connection to a Respiratory Integrated Thumper to provide continual circulation and oxygenation until washout began.

The MLSS, the integrated cart is used in this transport activity. This major asset, which Mike Quinn our paramedic/researcher is updating and improving, enhances SA’s ability to respond quickly to local Florida standby/transports (Mike is also making a portable version of the MLSS cart above for use on distant standbys.).

In early March SA participated in the transport of an Alcor patient in Southern California and a standby for another Southern California Alcor patient, whose condition improved. Meanwhile, SA personnel attended a week-long Alcor training session in Prescott Arizona. In addition to being students, SA personnel provided portions of the training related to blood washout and would have provided additional instruction had the Standby and Transport efforts not had priority.

The construction at SA has not progressed very far. The city of Boca Raton has moved ahead at glacial speed while processing permits and our construction has been held up accordingly. The vast majority of our equipment remains in local storage awaiting completion of our facilities, including a "procedure room" and associated scrub and support rooms, a pharmaceutical storage room, and two laboratories. One of the laboratories will be focused on supporting ongoing cryopreservation activities, while the other will be focused on R&D.

Work is underway on a whole body cooldown box that we hope will serve both traditional freezing and whole body vitrification patients. We are about to sign a long term contract for LN2, which will be stored inside our facility in a 10,000 liter dewar.

Meanwhile, Chris Dougherty has come aboard and is buried in literature regarding mitigation of ischemic damage. He is reviewing our proposed anti-ischemia drug protocol to find ways to improve it and reduce the labor required to produce and administer it.

 

 

Dave Hayes just got back from a week at LABVIEW school and is beginning to put together the software to run our computer controlled vitrification perfusion system.

We are still looking for additional staff, including paramedics, a physician and/or veterinarian, and a secretary receptionist/bookkeeper. Hopefully the next picture of our facility will show walls.

Dave Shumaker



Ben Best Addresses Transhumanists

On February 26, 2003, the Toronto Transhumanist Association hosted a talk by Canadian cryonics expert, Ben Best, titled, "Can Cryonics Save Your Life?"

The talk was held at the Parliament library from 6:30 until 8:15 PM. Interest and attendance was very good; we even had one attendee fly in from Montreal to attend the talk.

Ben Best is the President of the Cryonics Society of Canada and President & Secretary of CryoCare Foundation. Ben was also involved in the very first cyronics case in Ontario last year. We were honoured to have a speaker of

Ben's caliber come out for a TTA event.

Ben spoke for nearly 2 hours and addressed a wide variety of topics. He spoke of the science behind cryonics, the state of the industry, recent innovations, and the battle against aging. Ben also tied in a number of Transhumanist themes into his talk, including posthumanism, his optimistic view of the future ture, and the eventual goal of ending aging. He also fielded some challenging questions, and dealt with a number of difficult issues head-on.

After the talk a number of us relocated next door to the local pub where we had a few pints and discussed cyborgization, wearables (including recording devices), the nature of the human mind and consciousness, and life-extension.

All in all, it was an excellent and stimulating evening. The TTA would like to sincerely thank Ben for volunteering his time and expertise.

George Dvorsky

Vice-President, Toronto Transhumanist Association

Deputy Editor, Betterhumans



Another New Scientist Competition

John de Rivaz announced on Cryonet that New Scientist will hold another "weird competition." This time the winner will have their genome sequenced. The competition opens on 15 March, when details can be found in the magazine or on http://www.newscientist.com/competition

Previous contests have concerned the invention of a device to walk on water, and of course cryonics.

The other competitions don't seem to have produced anything like as much news coverage as the cryonics one in September 2002. But unfortunately this resulted in the winner, Helen Tibble from Congleton, Cheshire, choosing the alternative prize of a holiday in Hawaii.

Nevertheless nearly 30% of entrants would have chosen cryonics. The number of voters in a New Scientist poll timed to run with the competition produced a similar ratio.

There were three times the number of voters as entrants in the competition although it is likely that everyone who went in for the competition also did the poll. Translated over the population of the UK this suggests about 17 million

UK citizens would opt for cryonics if the government offered it on the National Health, ie free at the point of use but paid for by general taxation.

Sincerely, John de Rivaz: http://John.deRivaz.com for websites including Cryonics Europe, Longevity Report, The Venturists, Porthtowan,



Option Two Members Can Vote

Cryonics Institute's Board of Directors has voted to grant voting rights to Option Two Members if they have paid dues for at least three years and have fully executed and funded contracts. This applies to voting held at the Annual Meeting at CIHQ



CI Orders New Cryostat

CI has placed an order for an additional cryostat. They’re using the same supplier they used for the last one.



Another CI Visitor

Gigi Nicolas, a reporter for the SHOWTIME channel recently interviewed David Ettinger at the CI facility The interview was scheduled to run while the credits for VANILLA SKY were rolling.



 

 

By Jim Yount

Approximately seventeen cryonics activists, members of diverse cryonics organizations, met in Laughlin Nevada on Thursday, February 27, at the invitation of California attorney H. Jackson ("Jack") Zinn. Edgar Swank and John Day attended on behalf of the American Cryonics Society ("ACS"). David Ettinger of Cl, was also in attendance. I was not present, but got a report of the meeting from Jack and Edgar Swank. I am familiar with the circumstances that prompted the call for a meeting,

Early this year, a Northern California man was placed into suspension at the Cryonics Institute's Michigan facility, in accordance with provisions of his will and his longtime wishes. This individual, a Califoraia attorney, was a Cl member, as well as an ACS Associate. He, working with Jack Zinn has assisted ACS and Trans Time in a number of legal matters related to cryonics over the years. Since I don't know his desires concerning privacy I will not use his name in this report.

In making his suspension arrangements, the man established a cryonics trust, but did not nominate a trustee. At the meeting in Laughlin. Jack Zinn explained the circumstances of the suspension, the current status of the estate, and the fact of the trust to meeting participants. Jim Bianchi, Esq. the California attorney who wrote the model wills and trusts for ACS has agreed to assist with preparing trust documents, but much additional work must be done. Currently the executors are busy gathering information for probate, a considerable task in this case.

Jack Zinn, himself a long-time cryonics activists is the attorney for the executor, was a friend of the decreased, and was called on to assist in getting the patient released bv the Medical Examiner so he could be shipped to Michigan for cryogenic preservation.

Partly because cryonics is still fairly new and not widely known, each cryonic's case presents its own unique challenges. I accompanied Jack when he called on the Alameda County Medical Examiner to "spring" the patient. This success followed many hours where Jack and Cl personnel and volunteers were on the phone with relatives of the patient, with relatives attorneys, or with representatives of the Medical Examiner.

There are just two attorneys I know of, here in Northern California, who knew how to quickly get a patient away from the Medical Examiner and on the plane to our Suspension Facility, and one of them (the subject patient) was lying on a slab in a refrigerated morgue in downtown Oakland. Jack was a God send in this case. as he has been in a number of other such circumstances.

The purpose of the meeting was to brief representatives of the various cryonics organizations on this case, and the substantial trust to be established which could benefit cryonics research considerably. Various ideas to further cryonics research through the proposed trust were discussed as well. The meeting also considered administrative aspects of the trust such as the various individuals who may be available to work as advisors or in the capacity of trustee,



The Mardi Gras of Cryonics

By John Bull

Information for this article was gleaned from various cryonet posts, and an e-mail exchange with Bauge

When the CBS News show Sunday Morning featured the Frozen Dead Guy Days Festival on March 16, it was the first time the Festival received national media attention. Appropriately, the segment that carried it was usually reserved for reporting on the oddball and eccentricities of American life. They were right on the money in this case.

The origin of the festival goes back to November of 1989. That’s when Bredo Morstoel died in Norway. His grandson Trygve Bauge, packed grandpa in dry ice and shipped him to Trans Time’s facility in California, where the body was stored in liquid nitrogen. After four years Bauge moved grandpa to Nederland, Colorado, and placed him in a storage shed, packed in dry ice.

Originally, the local officials were against having the body stored there, but later relented a little, by grand fathering grandpa in!! Things were relatively quiet after that, except for the occasional film crew that came to do a story. Then about two years ago some of the locals with the Chamber of Commerce were trying to figure out a way to boost tourism.

One of them remembered "the dead guy in the shed," and from that the Frozen Dead Guy Days Festival was born. This year’s festival, the second, attracted folks from all parts of the country.

Some of the attractions were a coffin race, a movie, "Grandpa’s Still in the Tuff Shed," a parade of old hearses, Dead guy look alike contests, and for $25, a trip to the Tuff shed where Grandpa rests on dry ice. Tuff Sheds, the official home of Grandpa, were everywhere, from the coffin race’s finish line to the official headquarters, many of them stocked with Dead Guy Ale, T-shirts and similar paraphernalia.

Meanwhile, Bauge, having lived in this country for fourteen years without a visa, passport or green card was deported.

When asked if he would ever be allowed back in, he replied, "I qualified for the general amnesty that Ronald Reagan offered in 1986, but I did not apply for amnesty. I assume I would be allowed back in if I applied for a passport and visa. However, I prefer to work towards removing all passport, visa and work permit requirements. Basically, the way I see it, entrepreneurial liberty and life-extension go hand in hand. You won’t get drastic improvements in human life expectancy without entrepreneurial liberty. There was a time when people took pride in being un-documented and equated that with liberty. I still do." Considering conditions in the world today, he shouldn’t count on the light being left on for him.



Bauge recently referred to the Festival as the Mardi Gras of Cryonics. David Verbeke chided Trygve on Cryonet for the circus atmosphere surrounding Frozen Dead Guy Days. Verbeke, living in Belgium, is CI’s contact person for Belgians:

Mr. Trygve Bauge,

You're comparing this 'frozen dead guy festival' with Mardi grass. Your comparison is correct, although I think you have a rather wrong idea about the value of Mardi grass.

If it's Mardi grass, what do we see on TV? We see drag queens dancing half naked in the streets of a major city. That makes every gay man a stereotype fag in the head of many people, just like your show makes every cryonicist a crackpot in the mind of a lot of people who see and hear it. Remember that it wasn't those who were dancing half-naked in the streets that gave gays more rights. It was those who were doing the serious emancipation work and lobbying to politicians, trying to change their minds of those who were filled with pictures of Mardi grass.

Maybe some common folk may like this little party now, and the city tries to make some benefit from it. But will it last? Do you think such actions can build a solid soil for the rights of cryonicists? I'm convinced of the contrary.

Verbeke David

CI-member

philosophy student UG

http://groups.msn.com/cryonicsbelgium

Trygve's Reply:

Cheer up,

Let me quote the Danish Author Piet Heine: "The one that always takes the light lightly and the serious seriously,

he and she have understood both poorly!" This event isn't there to build support for cryonics in Colorado, it is there because of the support that Cryonics (thanks to yours truly) already has in Colorado!

The Chamber of Commerce is basically (with my approval) cashing in on the fact that my Grandfather is the most famous resident in the town of Nederland Colorado. His presence there has put Nederland on the world map and attracted film crews and TV stations to the town every year for the last 10 years. The Chamber correctly saw that this was an opportunity to get a festival going and to drum up some business. The United States was founded on the right to the pursuit of happiness, and what better way to be happy than with a fun Winter carnival?

It is a free world, (sort of) at least those who like to party are still free to do so, Luckily there is no Cryonics police trying to outlaw Cryonics related parties. If you think such parties are a threat to cryonics, then we disagree and luckily you don't have the power to stop our party.

The Frozen Dead Guy Days have lasted two years so far, and that is longer than most other events. My other large Winter carnival, the annual New Year's Day dip at Boulder reservoir just had its twentieth anniversary with more than 450 icebathers. Maybe Frozen dead Guy days will be as long lived? But if it doesn't so what?

The festival is just one of many activities organized around my grandfather's suspension over the years: An award winning short movie has been made, lots of TV programs have been made etc. I am favourable to activities that keep him and his situation in the public eye. It makes it easier to maintain him in the long run that way.

The Chamber of Commerce have organized the event and contributed a lot of volunteer efforts and money to get it going. (Their budget for the festival this year is USD 35,000 and they have had one director working on it full time for a year.)

I for one am grateful for the support.

I think cryonisists should use the opportunity that this festival is, and participate in the planning of next year's festival.

Here is a successful festival, and lots of volunteers, and all we have to do is to participate We could combine the festival with a cryonics conference at the local motel, and an information table on main street. There is a film festival paarallel to the Frozen dead Guy Days, so we could show selected cryonics movies as well

Ayn Rand died on March the 6th 1982. The calendar based on her death, has now come to: 21.004 (that is 21 years and 4 days after Ayn Rand). Thus the Frozen dead Guy festival is kind of a New Years party for those of us who

stick to this calendar. She didn't want to be frozen, though she knew Ettinger.

However, she wanted people at her death to celebrate life and achievement and life at its best, so a celebration is appropriate. The attempt to restore life to those that are frozen, is one of many possibly highly life-extending ventures, and certainly worth an annual celebration.

 

Trygve Bauge

trygve@...

Se: www.trygve.bauge.com



 

 

Reprinted with permission from:
The Libertarian Alliance
25 Chapter Chambers
Esterbrooke Street
London SW1P 4NN
England

E-mail: chris@...
www.libertarian.co.uk

© The Libertarian Alliance (From their cultural notes section)

If a mass death sentence defines man’s condition, then rebellion, in one sense is its contemporary. When he refuses to recognize his mortality, the rebel simultaneously refuses to recognize the power that makes him live in this condition." Albert Camus1

The continuing fact of death renders all talk of liberty ultimately futile. Brave notions of freedom which passively accept the certainty of personal extinction are increasingly seen as so much empty rhetoric. The gods have deserted us and our clever excuses for oblivion are wearing thin. In our hearts we know that there is something very wrong with our condition, and yet faced with the seeming inevitability of our fate we recoil from the obvious implications: we must save ourselves or perish.

THE APPROACHING VOID

Denied the prospect of survival through supernatural agency secular Western man has become psychically traumatized. Increasingly life seems meaningless and absurd, and the fear of death and nothingness lie just below the surface of everyday consciousness. Although the structures and institutions of religious belief linger, their function is now largely sentimental and ceremonial. The once faithful have deserted to the post-psychedelic spiritual supermarket in a frantic search for new answers to the problem of death. One of the modern prophets of scientific immortalism, Alan Harrington, argues that the anticipation of death is now the most important single determining factor in human behaviour.2

The effects are subtle but unmistakable. By limiting our horizons to a single lifespan the approaching void adds an urgency and desperation to our projects. There is a noticeable quickening of pace, a sense of little time left. Sometimes this is seen as a response to the threat of mass nuclear death; but collective mortality is an abstraction: death is only comprehensible at the individual level where it is experienced.

In any event, concern with the manner of our departure is dwarfed by the growing certainty that nothing follows it. Without the prospect of continuity there is a truncation of perspective and shorttermism dominates in a hot-house world. Our concern for the future begins to disappear with the likelihood of our own extinction. And yet to avoid emotional collapse we are compelled to devise defensive strategies.

WE DIE BEFORE WE DIE"

A common response is to hide from our fate by seeking distractions which help to reduce our sense of separateness, in the words of the song, in "sex and drugs and rock ’n’ roll". We throw ourselves into work and play; into conformity; and by living other people’s systems and creeds. Through communal action and the organic warmth of the crowd we achieve a swamp-like collective immortality, but at a heavy price. By becoming quite literally "Mindless", the precious ego which dissolves in death is deliberately scrambled ahead of time. As Harrington puts it, we "die before we die" and "commit suicide on an installment plan.3

Tragically, by sacrificing the rational ego we destroy the only true key to our salvation. Others rage at death. Faced with only a fleeting appearance in life’s arena desperate men seek ever more bizarre ways to erect monuments to their existence. The mass murderer, the assassin, the roof top sniper and the lone hijacker are all saying: "Don’t forget me. Kill me if you must but don’t forget me."

Responses from more ‘sophisticated’ men appear profound but, since they leave our condition unchanged, are just as futile. Subtle posturing ("A man who is afraid of death has never really lived"); and word games (death does not really exist); sound plausible. But in the middle of the night, alone with the void, the clever fatalist wants what we all want: survival. Lacking the courage to rebel openly he is driven to rely on ever more diluted and indirect notions of continuity. The traditional ersatz form of "immortality", being succeeded by our descendants, has now spawned a variant: survival through our genes. So Richard Dawkins in The Selfish Gene can argue that the sole function of the human body is as a vehicle to promote the survival of our DNA.4

The final development of this line of thought is that the body is, in the last analysis, pure Energy and therefore ultimately indestructible: death merely brings a change of form! Such sophistry may appeal to some in a bloodless sort of way, but it can only delay our assault on the one true enemy personal oblivion.

PERSONAL PHYSICAL IMMORTALITY
Another group, professing a concern for dispassionate scientific enquiry, but harbouring a thinly disguised religious impulse, clings to the vestiges of Cartesian dualism. But as brain science increasingly uncovers the physical basis of behaviour and experience, they are in perpetual retreat, pursuing the ‘God of the Gaps’. Any evidence of ‘independent’ mental activity, however insubstantial, is seen as the last refuge of the soul and with it the hope of a disembodied immortality.

Parapsychology provides a fertile source of examples. Archdebunker James Randi, quoted by John Taylor in Science and the Supernatural,5 commenting on how a band of PhDs in physics, chemistry and mathematics could reach convictions so contrary to their science, says: "Because I have seen what grown men will do to satisfy a deep need to believe." And yet supposing the psi people are right; can we really conceive how an incorporeal immortality could be satisfying. All the evidence suggests that personality grows with the body and is inseparable from it. As Wittgenstein observed: "The human body is the best picture of the human soul."66

What we want is personal physical immortality, nothing less. We need to survive as a psychosomatic unity with all our memories, thoughts, hopes and desires intact.

LIFE’S TERMINATION IN NOTHINGNESS

The great issues of death and survival were once the business of philosophers and theologians. But neither have been left untouched by the general spread of disbelief and both have retreated into narrower concerns. Academic philosophy has largely abandoned metaphysics in favour of arcane linguistic analysis, and the church has turned its attention to more mundane social and ecumenical matters. Death now seems something to be either ignored or accepted as the great given. In any event philosophy, according to Montaigne,7consists in learning how to die. So Alan Harrington argues that precisely because it teaches accomodation to death, philosophy’s practical usefulness has come to an end: "The philosophy that accepts death must itself be considered dead."8

Only the existentialists come closest to a true understanding of the fundamental significance of death. Those writing as atheists commonly and rightly seen as the purest representatives of the school recognise the central paradox: that the necessary freedom entailed by the absence of god is negated by life’s termination in nothingness. So Heidegger argues that to live authentically we must face squarely and constantly the boundary set by death and accept the anxiety that this brings. Sartre’s doctrine of "bad faith" performs a similar function, uncovering our strategies of self-deception, and attempts to avoid a personal response to death.

For example by seeking significance for ourselves as part of some deified abstraction like ‘Mankind’, ‘Humanity’ or ‘Nature’, rather than accept that we alone must decide the meaning of our life and death. Camus, protests against the "incompleteness of human life, expressed by death" rejects despair and calls for rebellion against the implicit consequences of extinction: "If nothing lasts then nothing is justified."9

Although the existentialists offered a particularly clear-eyed analysis they could in the end advocate only a kind of stoical acceptance of our condition; not shirking the anxiety it entails but seemingly lacking the means to challenge it. Even Camus’ call for rebellion, although admirable, is ultimately impotent. Perhaps the Existentialists were trapped in a transitional phase science had undermined the religious worldview but not yet begun to offer its own solutions.

WITHIN THE BOUNDS OF PRACTICAL SPECULATION

If Camus is right and death is the real enemy then it is not life after death that we want but the end of death itself, at least as an inevitable consequence of being born. Who then will take up the challenge against the conventional wisdom? Most ‘serious’ thinkers, although driven by the same emotional imperatives as the rest of us, fight shy of any public discussion of the topic, other than in mocking tones. So we see, for example, occasional coverage of the cryonics and life extension movements portrayed very much in ‘flat earth’ terms. A mainstream scientist who strays into these areas is quickly marginalised as an eccentric by bemused colleagues. As Thomas Kuhn pointed out, science is far from the purely rational and systematic process it pretends to be.10

Fortunately a small but growing band of heretics fringe scientists and speculative writers are challenging the current paradigms, and providing a platform for a legitimate discussion of the field. They argue with increasing confidence that science and technology can deliver what religion once promised; the age-old dreams of immortality may not have been wrong but they depended more on faith than fact. Scientific progress has now begun to allow personal immortality at least to be brought within the bounds of practical speculation.

Science fiction, in keeping with its revolutionary paradigm shattering function, has long provided a testbed for exploring scientific responses to the problem of death. Immortality and extreme longevity are recurrent motifs in SF, which has explored both the mechanical aspects and also the social and psychological implications. SF editor and critic Peter Nicholls, surveying the field, noted that "in some stories immortality is the beginning of limitless opportunity, in others it represents the ultimate stagnation and the end of innovation and change."11

But there is a general recognition that such themes exert a continuing power, typifying the Promethean spirit which is the essence of the genre. Although sometimes criticized as "escapist", SF may in fact be helping to prepare the ground for a quite literal escape from death.

"IN THIS REALM WE ARE KINGS"

Polymath writer and neoexistentialist philosopher Colin Wilson 12 has always shown a strong interest in the topic. His strongly optimistic view of man’s potential to evolve to Godlike status through consciousness expansion foresees a greatly increased lifespan as a consequence. He has acknowledged that in his novel Philosophers Stone he was trying to write, like his mentor Shaw in Back to Methusalah, a "parable of longevity".13Shaw can tolerate no limit to human possibility. He rejects religious concepts of imperfectibility and predestination (as well as the scientific concept of biological determinism).

Wilson is similarly motivated, but in a survey of his novels, writer Nicolas Tredell 14 notes an important difference in the attitudes of the two men. For Shaw, longer life produces greater consciouness; for Wilson greater consciousness yields longer life. So for Wilson longevity in itself is a legitimate aim, which he suggests will be achieved by an act of will.

Both he and Shaw seem to agree that man somehow chooses death, often through lack of an overall purpose, and a willingness to accept a passive life at the ‘animal’ level. Wilson argues that this is reversible when men develop a sense of evolutionary purpose. In support of this he even asserts that philosophers, scientists and mathematicians as a group are more long-lived than poets, artist and musicians.

Alan Harrington, author of The Immortalist a key philosophical treatise for the life extension movement is a spiritual ally of Shaw, Wilson and the existentialists. Like them he rebels against all forms of determinism but takes this rejection to its logical conclusion: "Death is an imposition on the human race and no longer acceptable."15

His project is twofold: first to strip away the protective myths and psychological strategies we use to avoid the central fact of existence: that we die meaninglessly and disappear into the blackness. Second: to encourage us to believe that through science we not only can, but must, construct our own divinity. Applauding the future of Unnatural Man Harrington quotes Bertrand Russell with approval: "We are ourselves the ultimate and irrefutable arbiters of value, and in the world of value Nature is only a part. Thus in this world we are greater than Nature ... In this realm we are kings and we debase our kingship if we bow down to nature."16

A CURE FOR THE DISEASE OF DEATH

In a practical sense, although unannounced as such, the road towards immortality has already begun. Medical technology continues to stretch our understanding of clinical death to the point where there is no longer a universally agreed definition of what the term means. Multiple organ transplants promise to replace more and more of our bodies with artificial equipment, offering the possibility of an almost indefinite postponement of death.

Through genetic engineering, man for the first time has the means consciously to influence biological evolution. So if various organisms have differing ‘natural’ lifespans governed significantly by genetic factors, then different or modified genes might permit longer life. It follows that if, as some surmise, aging is due to an accumulation of mistakes in the replication of DNA, then in theory at least new healthy material could be inserted into genetically defective cells.

Many healthy individuals are claiming benefit from life extending therapies aimed at slowing down and even reversing the aging process. Diet, exercise and the avoidance of some obviously damaging lifestyle practices, all play a part. Support is coming from the science of gerontology with nutrition appearing particularly important. Roy L. Walford,17 a pathology professor at UCLA, and his colleagues have shown that by severely limiting the caloric intake of rats, significant increases in lifespan were achieved. Walford believes a similar approach could be applied to human beings, and follows such a regime himself.

The mental influence on health is well attested. And as far as aging specifically is concerned, there also appears to be a strong cultural component at work. Social gerontologists note that age is not just physical, but also social. People are expected to behave in certain ways appropriate to their age, but most of the expected behaviour is not related to any biological process and shows great variation across societies and periods of history. Labelling an individual as ‘elderly’ or a ‘senior citizen’, if incorporated into his self image, may produce a self-fulfilling prophecy.

The expected decline in performance and health duly appears seeming to confirm the original description. David Lewis, in his book Life Unlimited,18 sees gold watch presentations and other retirement rituals as the Western equivalent of Aboriginal and voodoo death curses. Where such symbolism is deeply embedded in a culture its effect on physical and mental health can be profound. To see aging, at least in part, as a social construct is to begin to bring it under our control.

So the battle to conquer aging and death is underway, albeit in a fragmented and uneven fashion. Sober gerontologists in respectable institutions are making solid if unspectacular progress, and are at one with the movement’s radical wing, the proponents of cryonics and suspended animation, and those who speculate about the mechanical storage of human personalities: "electronic soul". All are ultimately engaged in the same project although, with no concensus yet on the causes of aging, the field lacks a unifying principle, and as Harrington observes, awaits its Einstein.19

Perhaps before science will respond more fully to the challenge we must, as Lyall Watson argues,20 break the rigid cultural linkage between death and permanency by regarding death simply as a disease and therefore temporary, and sometimes curable. Once this paradigm shift has been achieved it will be no more "unnatural" to seek a cure for aging and death than for illness.

TURNING INTO GODS

We know we must do it and that the effect will be profound. Jonathan Schell, in The Fate of the Earth, although discussing mankind as a whole, nevertheless echoes our project: "By acting to save the species, and repopulating the future, we break out of the cramped, claustrophobic isolation of a doomed present, and open a path to the greater space." With the creation of an open-ended future for individual men, we allow more space for reflection and wisdom. Shaw saw this in Methusalah and Walford believes that a world with an active population of 200-year-olds would not only be wiser but morally better, saner, more in control of human passions. There is little doubt that the heretics are gaining ground and that we will grow up and seek immortality in the only way possible. It will be science, intellect and analysis that will be our salvation not mysticism. In Harrington’s words: "We can only engineer our freedom from death not pray for it ... having invented the gods we can turn into them."22



.

 

THOSE OF US WHO DREAM by day are cognizant of many things which escape those who dream only by night.

 

SOME OLD WIVES tales have been disproven by modern medicine: It’s a myth that cuts and scrapes should be uncovered in order to "breathe." After cleaning a wound with soap and water, apply an antibiotic ointment, and cover with a bandage.

FEED A COLD, starve a fever is false. When you catch a cold you cannot sweat it out, drown it, starve it, or take medication to get rid of it. Antibiotics have no effect on colds. It usually takes at least 7-14 days to alleviate the condition, with or without medication.

CRACKING YOUR KNUCKLES will not cause arthritis. Some people think the sound is the grinding of cartilage or bone. Actually it’s air bubbles popping in the synovial fluid of your joints. USA TODAY

A DRINK A DAY might ward off dementia, Alzheimer’s. Research already has indicated that alcohol, in modest amounts, could help stave off heart disease. A new study suggests that moderate drinking also might ward off brain diseases such as Alzheimer’s which afflicts 4 million people in the USA. Ibid

I DON’T WANT TO ACHIEVE immortality through my work…. I want to achieve it through not dying. Woody Allen



MEET MARK WALKER

Editor’s Note: Mark Walker recently became Cryonics Europe membership manager, we welcome this opportunity to profile him.

I was Born in 1962 in Llanelli South Wales UK. When I was about four I moved to what was a small town called Burntwood in Staffordshire which is pretty much in the middle of the UK and have lived there ever since. I now live there with my girlfriend Gill who manages a specialist residential home for people with Parkinson's Disease.

We also have a few pets living with us; five cats, a Samoyed dog, an African Grey parrot, A Tortoise and a Rabbit. Although I consider Burntwood my home, my work can take me anywhere so it is quite useful to be fairly central.

I have an Electronics Degree and earn my living contracting as a control systems engineer. In simple terms this involves controlling or automating manufacturing systems, which can include valves, motors, pumps and conveyors Etc. This is done with a computer known as a PLC (Programmable Logic Controller). I have worked on projects such as lronbridge Power Station, Bass Brewery as well as Heathrow and Gatwick Airport Conveyor Systems. I have also worked in the car manufacturing industry but currently I am working at Pfizer Pharmaceuticals in Kent. I am primarily involved with writing and testing the software for these systems, although I do get involved in the electrical side especially during commissioning.

I don't get much spare time and working away a lot makes it difficult to follow up and take part in some activities, but below are some of the things I like to do when I get the chance.

I have 3 jukeboxes at the moment, two are restoration projects that I have partly restored; an Ami K and a Wurlitzer I I 00. I also have a Wurlitzer OMT complete with bubble tubes, which Wurlitzer recently produced and is based on the 1050 .

I enjoy most types of music, from light classical to rock music, but I draw the line at Opera something I can't get into at all. My favourite music however is dance music and I enjoy going to night clubs, I may not be the worlds greatest dancer but I love the music and atmosphere.

Something I always have time for is computers, whether its building new ones for friends and family, upgrading mine, surfing the net or playing games on them, especially strategy or shoot them up games. You would think I have enough of computers at work, but I love them. My recent project is to incorporate a PC as part of my Hi Fl system to play MP3 discs and control my CD Mega-changers. I also enjoy rifle and shotgun target shooting and am a member of local club in Burntwood.

I also watch a lot of TV mainly SCI Fl, I am a big Star Trek and Stargate fan and my favourite films include the Matrix and of course the Star Wars films.

I love Technology and I am a bit of a gadget person another reason I chose Cryonics, not only am I taking part in a Technology I may get the opportunity to see future technology first hand.

I am also a bit of a collect-a-maniac I collect things to do with Owls because I think they are fascinating and I also collect Phone Cards, DVD's Laser Disks, and CD's I have a great problem throwing things away.

When the Grand Prix season starts everything stops, I love to watch the Grand prix and with the latest changes I think this is going to be a good season, luckily the girlfriend also follows it and we a both members of Team McClaren.

I also enjoy DIY which is just as well as there always seems to be something that needs doing on the house. A couple of things I really don't get time to do but would love to do more of is flying, the girlfriend brought me a flying lesson for my birthday and I loved it I also love Paragliding but this ,tends to be limited to holidays at the moment. I also have tickets for a Hot Air Balloon flight which I am looking forward to.

I am not sure of the date, maybe 20 years ago or more. I was off work and watching Morning television, one of these mixed shows where they have news, guests and other various features. Anyway I wasn't paying much attention when the presenter of the show stated, "after the break we will meet a family who have signed up to be frozen when they die." This certainly got my attention and I eagerly waited the end of the commercials.

These people look quite normal, was my immediate reaction. I was intrigued and excited as they told their story about wanting to live and having the opportunity to do so in the form of Cryonics. I remember thinking these people are obviously rich and if I ever managed to become a millionaire Cryonics was definitely for me. A telephone number was shown at the end of the interview for further information, I didn't call it then but made a note of it and transferred it to my address book. This must be the one contact number that managed to survive the years and was transferred from gadget to gadget and ending up in my mobile phone.

It was some 17 years after first seeing it on TV that I started to do something about it. I was heavily into computers and the internet at the time and while thinking of things to search for on the internet I decided to try Cryonics. To my surprise found several Sites and started to read the information on the various sites.

Hang on a minute, was I reading this right, 28000 US Dollars for a full body suspension, this was looking affordable after all. I then decided to try the number I had, as all the web sites seemed to be in the USA and the number was a UK number. Surprisingly it was still in use and a funeral director answered the phone, who I now know as F.R Albin. So after a bit of a chat the forms and information pack were sent out in the post.

When the forms arrived and I doubled checked the prices I filled in the membership application form and sent it off with my cheque. I went for option 2 which would cost me 120 Dollars a year until I could afford full membership, option one.

The next step was to make arrangements for the suspension itself. I read through the contract and other forms and although not compulsory some of the forms required signatures from my next of kin which basically meant them giving their consent and agreeing not to interfere with my wishes.

Time to go public, I had mentioned it in the past without much response, but now it was actually going to happen. So I discussed it with close family and got the reaction I expected, "you've been watching too much Star Trek." However although they were quite shocked, they realised I was serious and agreed to sign the forms. Right so far so good and now, last but not least, the life insurance.

Here I had a few problems, each insurance company I tried seemed to have a problem in me having a named beneficiary in the states.

But there must be other members in the UK who have already done this, so after speaking to Barry Albin, he put me in touch with his financial advisor who in turn set me up with a policy, which I was then able to sign over to Cl. All my documents were signed and together with my proof of founding they were sent to Cl. Soon after I was contacted by Cl to who confirmed, not only was I a member but I was now also signed up for suspension.

Well that was it, now what, get on with the rest of my life I guess. I continued to read the few news groups I could find and even made friends with a young Russian Cryonicist but something was missing. I guess I felt isolated, was I the only person in the UK signed up for this. My Russian friend and I even thought of starting a website where cryonocists could chat and arrange to meet each other, but after contacting the various Cryonics organisations, most of them turned us down flat and although Cl showed some interest it never got off the ground.

I don't know whether this prompted Cl, but several weeks later I had an E-mail from them explaining a group of Cryonicists in the UK (yes the UK) were having a meeting down in Eastbourne and were after a Cl member to join the meeting. I couldn't believe it this was great, I was so excited and agreed straight away.

Well the big day arrived I was both nervous and excited, but one thing in the back of mind while I drove down to Eastbourne was the date, April the 1st 2001. This couldn't be could it; nobody would do this as an April Fool would they. Well I . arrived and my concerns and my nerves disappeared and I was left with excitement. The first Cryonicist I met was Alan Sinclair at his home where the meeting was being held together with his wife Sylvia I then met David and May Flude before the other guests started to arrive. I also met a fellow Cl member for the first time Chrissie De Rivaz.

During the meeting the group we now know as Cryonics Europe was born and I gained many new friends for life, and maybe the next life. Since then I have been involved with the CE as much as possible and things are getting better and better. Cryonics Europe is a support and socialising group in the UK where like minded people can meet up and discuss anything they want. We also have a Standby team and encourage members to take part in meetings and in the team.

The more you do for cryonics and other member the more you are helping yourself. I now have several roles within CE which include secretary and membership manager and first team leader on the stand by team.

As part of CE I help with problems that members or potential members may have. I also help cryonicists sign up to their chosen provider. I also try and come up with new ideas to help the Cryonics movement. Cryo Buddies is the latest idea, we are trying to get off the ground.

Many Cryonicists nightmare is dying and being left undiscovered. So by putting such members in contact with each other so they can take it in turns to call one another a couple of times a day we can hopefully improve the situation.

I have also been involved with the media appearing in several newspapers and on a London radio station.



 

LIFE EXTENSION NEWS

 

How About That Gallbladder?

Small organs play a major role in maintaining good health.

Consider the gallbladder, which is only 3 to 4 inches long. This pear-shaped organ stores and releases bile, a powerful digestive agent produced by the liver.

Bile contains cholesterol, bile salts, lecithin, and other substances, including toxins filtered from the blood by the liver. Approximately 1pint of bile moves through the gallbladder every day. When food arrives in the small intestine, the gallbladder sends bile there to break down fats as they pass through the duodenum. Toxins contained in bile are eliminated with other wastes. Then, in one of the body's amazing feats of recycling, most of the bile acids that have been delivered to the duodenum are absorbed back into the blood.

WHAT ABOUT STONES?

When the gallbladder functions normally, healthy digestion proceeds the way it should. When it doesn't, gallstones (or cholelithiasis) and inflammation of the gallbladder (or cholecystitis) can be the result.

Some 20 million Americans have gallstones, but many of them don't even know it. That's because an estimated 80 percent of all gallstones cause no symptoms and need not be treated. Unfortunately, the remaining 20 percent can cause medical emergencies. Pain in the upper right quadrant of the abdomen that's accompanied by nausea or vomiting may signal the presence of a gallstone that's stuck in the bile duct. Gallstones can be tiny (the size of a grain of sand) or as large as a pea.

RISK FACTORS Large, infrequent meals, foods that are high in fat, and refined carbohydrates are risk factors for gallstones. Ironically, extreme low-fat diets are a risk factor, too. Avoid processed and hydrogenated fats, but don't eliminate essential fats, like fish and flax oil, from your diet. Other risk factors for gallstones:

- rapid weight changes (yo-yo dieting) - lack of exercise

- gender (women get gallstones four times as often as men)

- age (one-fifth of adults over 65 have gallstones that lead to problems)

-combinations of factors (fair-skinned, overweight mothers over age 40 are prone to gallstones).

Gallbladder inflammation, which can coincide with the presence of gallstones, causes intense pain that lasts from 30 minutes to several hours, often in the evening. In some cases, the pain resembles that of a heart attack because it often occurs in the chest or spreads from below the breastbone into the shoulder area and upper back. Any upper abdominal pain that lasts for more than an hour may be due to gallbladder disease and requires medical attention.

SUPPLEMENTS CAN HELP

Several foods, herbs, and supplements help the digestion process by improving gallbladder function.

Often extracted from soybeans, lecithin is a type of fat found in brewer's yeast, eggs, fish, grains, legumes, and wheat germ. A good multivitamin-mineral supplement helps prevent the nutritional deficiencies, including inadequate vitamin C and B, complex, that contribute to gallbladder problems. Several herbs are recommended for the gallbladder, including Oregon grape root, ginger, and turmeric. These are available individually as teas, extracts, and capsules; as spices; and as' fresh foods. Of the many foods that are gallbladder-friendly, the most versatile may be the apple, whose juice is cleansing and can help to soften gallstones.

- Cj Puotinen Adapted from HEALTH

Do You Have Sarcopenia?

Much of the disability associated with aging is from loss of muscle. If, as a child you broke your arm, it was placed in a plaster cast, and when it came off, your arm was shrunken and weak. This, in effect is the condition in the elderly we today know as sarcopenia.

Here are the facts about sarcopenia: It was identified in the 1980’s by a researcher at Tufts University: Beginning at around age 45, normal muscle loss starts. It progresses at about one percent a year. With a decline in muscle loss, strength is compromised.

Suddenly, or so it seems, you have trouble climbing stairs, lugging grocery bags, or lifting a grandchild. Life stops being pleasurable or easy. You find yourself thinking, "I can’t go for my walk today." Grudgingly, you accept "growing old is lousy, but this is just the way it goes."

Well, it doesn’t have to be that way, because strength training defeats sarcopenia. Again and again, research has shown this to be true, even with 90 year old nursing home residents.

In one study, two formerly sedentary seniors were able to throw away their canes after only weight weeks of supervised weight training.

Sarcopenia is made worse by disuse or lack of exercise. Feeling weak or inadequate, the older woman or man turns sedentary, even reclusive and fearful. Conversly, when you work out, you build muscle, and hiking, gardening or swimming again feels good. You’re back into life, enthusiastic and confident

"We are never too old to be fit," wrote the late Dr. George Sheehan. "We must accept responsibility for our health. We must realize living is an art, and life is an achievement. Life is not a gift or possession, it is our final battle."

Adapted from FLORIDA TODAY



Wealth Preservation for the Cryonically Suspended

© 2003 James Wm Clement*

 

James Clement

James Wm Clement, J.D., LL.M. (Taxation from N.Y.U.), is an attorney and financial consultant who has specialized in International Tax, and Trust & Estate planning, for nearly 20 years. He is also an entrepreneur who has founded and managed a number of startup businesses. Mr. Clement recently became a member of Alcor.

According to Benjamin Franklin, "In this world nothing is certain but death and taxes." Of these two certainties, cryonic suspension might make the former only a temporary state, rather than a permanent one. By immersing a person's body in liquid nitrogen immediately after death, Cryonicists hope to preserve the body and, more importantly, the mind of the person until advancements in science and technology allow the body to be unfrozen and repaired of the damage which caused the initial death and any damage caused by the freezing and thawing process. The primary technologies which must progress to allow for this repair are nanotechnology, artificial intelligence, neuroscience, and cloning.

Cryonics companies like Alcor suggest the funding of their suspension services through the purchase of life insurance, with the Company being named as the beneficiary of the policy. While this type of funding pays for the suspension services, what will the people who are being currently frozen, awaiting the miracles of future technologies, face financially if and when they are successfully reanimated? Money has been around nearly as long as humans have traded. Gold has been used as money for at least 40 centuries, and silver for about 25 centuries. The Romans had their Denarius, and the middle ages gave us the Thaler (later changed to daler, and eventually to dollar). It seems highly unlikely, even in the seemingly utopian world of nanotechnology capabilities of the future that money will become superfluous. Thus, what should a person planning to be suspended do to provide for his/her financial security in the world of the future?

Creating a Post-Reanimation Fund

At present, for purposes of the law, a cryonically suspended person is considered legally dead. Until such laws are amended, property owned by a deceased person is disposed of by statute or testamentary declarations. However, while alive, a person can plan or execute the transfer of property into one party's control for the benefit of another person via a legal entity called a trust. The trust can be established and funded before the person's death (an inter vivos or living trust) or pursuant to a will (a testamentary trust). There are several ways to go about setting up such a fund; independently or with a group (pool) of other participants. In the case of the former, the initial cost should range from US$3,000 to $5,000 and the annual maintenance cost should be about $1,000 and/or one-percent of the net increase in the value of the funds (paying the fund manager). The more elaborate the structure (primarily to provide redundant oversight), the more expensive it will be.

The source of assets for the Fund can come from the personal assets of the suspended person, from insurance or death benefits, and from gifts from relatives and friends.

Regardless of the legal entity used, the goal of the Fund will be:

1) preservation and/or growth of the value of the fund's assets;

2) protection of the fund from government encroachment (including forced disposal by operation of law);

3) protection of the fund from fiduciary fraud; and

4) utilization of the fund by the reanimated grantor/beneficiary.

I will attempt to review these goals in more detail and propose methods of achieving these goals.

Preservation of Value

The general economic possibilities of the future can be summed up in four periods:

1. Prosperity: A period during which the money supply stays stable or increases at a rate equal to improvements in production. During this period business, interest rates and unemployment is stable or getting economy is stable or growing, business is thriving, interest rates are low and stable, and unemployment is declining.

2. Inflation: A period when the supply of money increases, creating a rise in consumer prices. Depending on the rate of the money supply increase, prices might rise moderately or at a runaway rate.

3. Recession: A period during which the growth of the supply of money in circulation slows down and prices fall and the economy starts slowing down.

4. Deflation: The opposite of inflation. A period when the money supply decreases creating a decrease in consumer prices.

In his book Fail-Safe Investing, Harry Browne proposes protecting one's wealth for all four of these economic environments by creating a portfolio balanced between cash (currency), gold, stocks, and bonds. According to Mr. Browne's analysis of this portfolio over a 29-year history, it would have appreciated an average of 9.9% from 1970 through 1998, despite the numerous fluctuations in the economy (including the near-runaway inflation of the '70s, the stock market crashes of the '80s and '90s, and the periodic rise and decline in interest rates). The methodology for balancing the portfolio and suggestions for specific investments within the general categories are outlined further in his book.

Whither Tax-Haven?

Compound interest is the interest which is calculated not only on the initial principal but also on the accumulated interest of prior periods. This principle can be applied to the profits from any investment (dividends, capital gains, etc.) not just interest. If those profits are subjected to income tax, there is obviously less to reinvest and earn profits than if the profits are not taxed. Over a 40-year period, this difference in having investments compound tax-free rather than taxed is enormous. Assuming a 40-percent tax rate and an annual appreciation of 10%, a portfolio starting at $10,000 would be worth $76,861 at the end of 40 years, whereas the same portfolio untaxed would be worth $281,024. That's a 366% increase in the portfolio via the compounding of the tax savings.

There are numerous jurisdictions in the world which allow the accumulation of wealth without taxation. Such jurisdictions are known as tax havens. To a limited exception, the United States is a tax haven for non-resident non-citizens (the U.S. generally doesn't tax interest or capital gains earned by foreigners). Although the Internal Revenue Service has a long-standing history of fighting the usage of tax havens by U.S. citizens, there are many legitimate ways to do so and reap the benefits of low or no-tax jurisdictions. The offshore investment world is less regulated than what most Americans are used to, and is ripe with scams, over-zealous and often ignorant (as to American tax and securities laws) promoters. The cost of going "offshore" will be slightly higher than staying "domestic," and will require a great deal more due-diligence regarding the selection of the fund management. Because the laws are so complex in this area, it is extremely advisable that anyone wishing to utilize offshore tax havens do so only with the assistance of a reputable consultant.

Domicile

Regardless of the legal entity used, or the initial domicile of such entity, it will be important to safeguard it from legal encroachment. This can happen through the expropriation of the property, an increase in the tax rates applied to the assets or profits of the entity, or by changes in the laws protecting and regulating such entities. It is important that the organizing documents (charter, trust deed, by-laws, etc.) allow for a "Protector," who can legally change the domicile of the entity, should something unfavorable happen in its initial jurisdiction. It would also be prudent to maintain the physical assets (cash, shares, bonds, and bullion) in different countries, which have a long history of stability and preserving property rights.

Fiduciary Protection

Just as it's important to protect the assets of the entity from expropriation and taxes, it's possibly more important to protect them from embezzlement, fraud, or incompetent management. The entity documents need to set up a checks and balances approach to internal management, require independent auditing, and forbid self-dealing (where the trustee or managers pay themselves or companies they own for property or services).

Utilization of Funds

Despite the protections necessary to ensure that the assets will be available when the person is reanimated, the documents need to be flexible as to the types of payments which can be made on his/her behalf before, during, and after reanimation.

Before: the cost of reanimation may be significantly more than the amount funded for the cryonic suspension. Also, it may be advisable to change the way the body is preserved, or treat it with special processes, which might be beyond the financial ability of the Cryonics Company. In any case, the funding of these processes or treatments might fall on the Fund rather than the Cryonics Company.

During: it might be possible that certain improvements in human genetics, bio-mechanics, or nanotechnology might be accomplished during the suspension period which the person would like to take advantage of while he/she is being reanimated (examples might include the repair of defective genes, and the installation of enhanced body parts including sense organs, memory storage, and brain functions). These procedures might be expensive and

hence not covered by the normal reanimation fees paid for by the Cryonics Company. The Fund might be able to take advantage of these improvements and incorporate them into the reanimation process.

After: at this time we don't know whether a person will be physically and mentally healthy immediately upon reanimation. Under some scenarios, a person might lose part of his/her memory and need to be "retrained" how to move, speak, understand, etc. Further, the society that such person is reanimating into may have progressed such that new skill, language, or understanding will be necessary before they can safely be discharged into the world. Liken this to being a child again. Under any of these scenarios, it would be desirable for the Fund to be able to pay for the maintenance, supervision, schooling, or therapy of the person until he/she is capable of self support. Finally, upon the person's full recovery and assimilation into society, the fund should disperse the assets back to the person to utilize as he/she sees fit during the remainder of their lifetime.

Suspension/Reanimation Research & Support: I personally believe that this is a highly desirable purpose, but that the funds for such should be left to a dedicated trust or research organization rather than lumped together wit the wealth preservation fund. This research trust or fund should have many of the same safeguards as the wealth preservation fund, but would be created with the specific purpose of spending its income rather than preserving same.

Conclusion

The purpose of this article was to present some of the issues that should be considered when preparing post-suspension financial arrangements. Since the law does not yet recognize the "rights" of the suspended person (considering such person to be legally dead), it is necessary to consider the existing laws carefully and to protect oneself from every conceivable event which could result in the loss or significant diminution in value of the assets being held awaiting reanimation. I hope this article will stimulate such thought and planning.

 

 


General News Items

Important Note: A lot of these items are from sources designed for public consumption and contain no references or further information. It is up to readers to do their own web searches or whatever for further information.

 

2 April
 
LOS ANGELES (Reuters) - Shares of ICN Pharmaceuticals Inc. (NYSE:ICN - News) rose 18 percent on Tuesday 1 April amid the World Health Organization's listing of its anti-viral drug ribavirin as a treatment for severe acute respiratory syndrome (SARS). more on http://biz.yahoo.com/rb/030401/health_icn_stocks_1.html
 
New drug helps heart failure patients
United Press International
 
People who have suffered a heart attack and who have further signs of heart weakening will benefit from a drug already used to treat high blood pressure, doctors said Monday.
 
In fact, patients treated aggressively with the drug eplerenone for their heart failure -- a progressive deterioration of the ability of the organ to pump effectively -- did the best in the new study, which was reported simultaneously at the annual meting of the American College of Cardiology and in the April 3 issue of the New England Journal of Medicine.
 
"This study shows that on top of what we can do today for patients, we can still do better," said Dr. Bertram Pitt, professor of medicine at the University of Michigan in Ann Arbor. "This represents a new advance in the treatment of heart attack and heart failure. This is very satisfying."

4 April
 
Drug Slows Progression of Alzheimer's

United Press International--A new drug marketed in Europe is effective in stalling the progression of moderate-to-severe Alzheimer's disease, researchers said Wednesday. The drug, memantine, is the first treatment to show promise in combating late-stage Alzheimer's, which is characterized by a slow deterioration of mental and physical faculties and is the leading cause of dementia in people over age 65. The medication is a complete departure from current drug strategies available to treat the disease. Memantine works by inhibiting glutamate, a chemical that excites neurons and causes damage to brain cells involved in memory and learning.
 

7 April
 
U.S. Scientists Unveil 'Bird Flu' Vaccine. 
Los Angeles Times (www.latimes.com) (04/04/03)
 
A team of scientists from St. Jude Children's Research Hospital in Memphis, has developed a vaccine against the deadly Hong Kong 'bird flu.'  Dr. Robert Webster, a flu expert at St. Jude, says that H5N1 influenza does not appear to be contagious from person to person, but rather it leaps directly from species to species. But, he added, it has already mutated to infect several new bird species and could continue to mutate, and so it is imperative that they be able to move the new vaccine into human trials as quickly as possible.  The H5N1 flu strain emerged in Hong Kong in 1997, taking the lives of six people and infecting 18 others before the virus was traced to the open-air poultry markets and stopped by the massive slaughtering of 1.5 million chickens and other birds.  A few months ago, H5N1 re-emerged, prompting Hong Kong authorities  to slaughter several thousand more chickens, but the virus had already spread and killed ducks and flamingos in some city parks.   Researchers point to the current SARS phenomenon as an example of how quickly  and suddenly a new infectious disease can occur.
 
Australia Invents New Mousetrap with Herpes Virus
 
Australia, regularly hit by the worst mouse plagues in the world, is claiming an international first with a genetically modified herpes virus to knock out population explosions of the small rodent.
 
The government-backed Co-operative Research Center (CRC) for Biological Control of Pest Animals has produced a genetically modified herpes virus that makes sexually prolific female mice infertile, by blocking sperm from entering their eggs.
 
"We know it works in a shoe box-level experimental setting. Now we want to try it in a field setting," CRC director Tony Peacock told Reuters on Monday.
 
The CRC is applying to Australia's watchdog on transgenic applications, the Office of the Gene Technology Regulator, for permission to trial the herpes virus in sample populations of mice, in rodent-proof pens.
 
The disease can only be spread by mouse-to-mouse contact, after inoculation of rodents with gene-spliced material containing the modified virus.
 
Rigorous testing to prove the virus is "species specific" -- which means that it cannot be transferred to other animals or humans -- will be required before expected full release in three years.
 

 
11 April
 

Magnetic crystals in brain linked to Alzheimer's 
 
NewScientist.com news service
 
Tiny magnetic iron crystals in the brain may be linked to the development of Alzheimer's disease, suggests preliminary research.
 
If further work confirms the hypothesis, it could be possible to diagnose patients with early Alzheimer's disease by measuring the level of iron oxide crystals, called magnetite, in their brains.
 
Jon Dobson at the University of Keele, UK, and his colleagues examined six brain samples and found that magnetite levels increased with Alzheimer's disease severity, the first time such a link has been shown. "If the data continues to go this way, the implications are quite profound," he told New Scientist.
 
 
Drug May Protect Against 'Dirty Bomb' Radiation
 
A U.S. company says it has developed a drug that could protect people against the effects of "dirty bombs" and other kinds of nuclear attacks.
 
The drug is called HE2100 and was created by Hollis-Eden Pharmaceuticals. The company says early tests on animals indicate the drug helps the body produce white blood cells much more quickly, BBC News Online reports.
 
High radiation levels destroy white blood cells, which the body needs to protect itself against infection.
 
Radiation can also destroy the body's ability to form blood clots, leading to death by bleeding. The new drug may also help stop such radiation-induced bleeding, company officials say.
 
The test findings were presented at the annual scientific meeting of the British Society for Haematology.
 
If larger trial test results are successful, the company will apply for permission to sell the drug in the United States, the news service says.

13 April
 
Patients Warned Over Internet Drugs

World Entertainment News Network -- People who take medicine bought over the internet could be putting their health at risk, according to experts. A survey of more than 100 pharmacy websites has found that few provide customers with adequate information to enable them to use the medicines safely and effectively. Many also failed to inform customers of the potentially dangerous consequences of taking different types of drugs at the same time.
 

 
16 April
 
NASA Science News for April 14, 2003

Glass made of metal. Glass so clear that fibers thousands of miles long would be transparent.  Glass that travels through the body to destroy cancer. These are some of the wonderous types of glass than can be formed in the weightlessness of space. NASA researchers are working to bring some of them down to Earth.

FULL STORY at

http://science.nasa.gov/headlines/y2003/14apr_zeroglass.htm?list687582

which includes glasses which are so insoluble in the body that they are being used to treat cancer by delivering high doses of radiation directly to a tumor site.
 

17 April
 
Little-Known Operation Restores Sight
HealthScoutNews
 
A little-known variation on a corneal transplant is saving the sight of people with rare diseases or chemical and heat burns, reports The New York Times.
 
In the procedure, surgeons graft stem cells from a donor or the patient's good eye to the injured one. The cells are taken from the limbus, a rim around the cornea, which normally keeps the cornea clear. But when the cornea is injured, scar tissue clouds it over, causing blindness. The stem cell transplants allow the eye to regrow clear tissue, restoring sight.
 
In the United States, where the operation is performed about 300 times annually, the procedure has a 90 percent to 100 percent success rate in restoring sight loss stemming from industrial accidents, burns, and damage from contact lenses, the newspaper says.
 
The operation was also performed by Iranian surgeons on dozens of victims of mustard gas in the Iran-Iraq war during the 1980s, the Times reports.
 

 
18 April
 
Prozac 'Could Beat Cancer'

World Entertainment News Network--The anti-depressant drug Prozac could help doctors tackle cancer, says a British-based research team. The drug has been around for well over a decade, and is an established treatment for depression. However, in recent years, doctors have suggested it might have other benefits. Researchers from Birmingham University looked at the effects of a variety of chemicals on cancer cells of a type called Burkitt's lymphoma. This type of cancer - a type of non-Hodgkin's lymphoma - frequently develops in Aids patients, whose weakened state means that conventional chemotherapy may not be appropriate. It is an aggressive and frequently lethal form of the disease. The scientists found that even moderate doses of Prozac appeared to trigger "cell death" - a process in which the cancer cells "commit suicide".
 

 
19 April
 
Ancient DNA May Unlock Life's Secrets
AP
 
Ancient plant and animal DNA found in undisturbed soil sediment can be used to unlock secrets about life hundreds of thousands of years ago, researchers say.
 
Scientists analyzing soil from Siberian permafrost and from caves in New Zealand said they found evidence of DNA from animals that died out thousands of years ago and from plants that lived about 400,000 years ago.
 
Eske Willerslev of the University of Copenhagen, a co-author of the study appearing in the journal Science, said the study found that soil fragments the size of a sugar cube can contain large amounts of DNA from those ancient life forms.
 
"You can obtain a lot of information about that extinct biota from just two grams of material," Willerslev said.
 
Permafrost is excellent at preserving the ancient DNA, the researchers said, because it is constantly cold. The scientists identified DNA from 19 categories of plants and from eight kinds of animals, including the extinct mammoth and steppe bison. The animal DNA was thought to be up to about 30,000 years old.
 
Cholesterol Drug Approved to Prevent Heart Problems
HealthScoutNews
 
The anti-cholesterol drug Zocor (simvastatin) is effective in reducing the risks of heart attacks, strokes and the need for bypass surgery and angioplasty -- even in people whose cholesterol isn't above normal levels, the U.S. Food and Drug Administration says in approving new labeling for the drug.
 
Approval was based on a 20,000-person clinical trial known as the Heart Protection Study. Participants' risk of death from coronary heart disease fell by 18 percent; the risk of having a non-fatal heart attack was reduced by 38 percent; and the risk of stroke dropped 25 percent. The need for procedures to unblock clogged arteries fell as much as 30 percent, the FDA says.
 
The decreases were seen among people of all ages and baseline cholesterol levels, the agency adds. And it didn't matter if participants had heart disease or diabetes.
 
The FDA reminds people who take Zocor to be aware of any muscle pain, which may indicate a serious side effect called rhabdomyolysis, a muscle breakdown disorder. Symptoms can begin as fatigue, fever, nausea and vomiting, severe muscle pain, weakness and tenderness, and end up as cardiac arrest or heart attack.
 
Toshiba develops way to detect diabetes without blood sample
Kyodo News
 
Toshiba Corp. said Thursday it has developed a new method of detecting diabetes without taking blood samples, together with Sysmex Corp., a medical test equipment maker.
 
The companies have developed a device that can be worn by a person taking the test on his or her wrist.
 
The device will send out a weak electric current which will cause a small amount of body fluid to form on the surface of the skin.
 
Testing the blood sugar level of the fluid will be enough to discover the illness and its status, Toshiba said, adding the method will reduce pain and burdens for patients who often have to undergo blood tests more than once aEday.
 
The partners aim to make the new device commercially available in fiscal 2005, starting April of that year.

22 April
 
Gene therapy 'cured' diabetes in mice
 
United Press International--A new gene therapy has been found to temporarily cure mice of diabetes by triggering cells in the liver to produce insulin and other hormones, according to a new study released Sunday. Researchers led by Dr. Lawrence Chan, a professor of medicine and molecular and cellular biology and also the chief of the division of diabetes, endocrinology and metabolism at Baylor College of Medicine in Houston, Tex. said this new treatment offers a great deal of promise in managing a chronic illness that afflicts millions worldwide and is one of the most common diseases in the United States. "We have broken the barrier of the concept that you can turn one type of cells into another type of cells in the body," Chan told United Press International. "I think that's a pretty important proof of principle.
 
Stem cells might help fix failing hearts

United Press International--Adult stem cells improved the heart function of patients seriously ill with congestive heart failure, giving hope the cells one day could be used to restore damaged hearts, a study released Monday concludes. In one of the most comprehensive examinations of its kind to date, researchers from the Texas Heart Institute injected adult stem cells directly into the hearts of 14 patients in Brazil who were suffering from a severe form of heart failure and had no other medical options available. Although still considered experimental, adult stem cells have the potential to become various cell types in the body and thus repair damaged tissue.
 
Daily dose of sunscreen can slow growth of premalignant skin lesions

AFX News Limited
 
A daily application of sunscreen can significantly slow the development of sun-related skin lesions, a widely recognised risk factor for skin cancer, a study released Monday said.
 
A study of 1,600 Australians showed that volunteers who slapped on the factor 16 on a daily basis developed the lesions at a rate that was 24 pct slower than that of volunteers whose sun-care routine was less consistent.
 
"The study indicates yet again the great potential value of cutaneous sunscreen application, when undertaken conscientiously and carefully, against the now extremely well-documented ravages of sunlight in both the short and long-term," said John Hawk, a dermatologist at St Thomas Hospital, London.
 
These premalignant skin lesions are among the strongest predictors of skin cancer risk, according to the study in the Journal of the American Medical Association's Archives of Dermatology.

25 April
 
Bile 'Limits Stroke Damage'

World Entertainment News Network
 
An injection of a bile acid could reduce the number of brain cells which die in the wake of a stroke or serious head injury.
 
Researchers from the University of Minnesota claim that the substance, extracted from digestive juices, could interrupt a chain reaction of cell death and perhaps reduce disability.
 
Bile is produced in the liver, and flows into the digestive tract to help the body absorb fats. It's made in our own bodies and causes no significant side effects when given as a drug to animals The research team took a component of this, an acid called tauroursodeoxycholic acid (TUDCA) and injected it into the artery supplying the brains of rats who had suffered a haemorrhagic stroke.
 
A drug to mimic Caloric Restriction proposed.
 
There is now scientific evidence that a therapy can slow the aging process in laboratory animals. BioMarker Pharmaceuticals (www.biomarkerinc.com), a new company funded by the Life Extension Foundation, has discovered that metformin, a drug used to treat diabetes, can mimic many of the changes in gene expression found in calorically-restricted mice, which live much longer, healthier lives than normally-fed mice. More on
 
Clock of ages
 
New Scientist vol 178 issue 2391 - 19 April 2003, page 26
 
The way evolution works makes it impossible for us to have genes that control how long we live - or does it? It may be time for a major rethink, says Garry Hamilton
 
"AT ITS most extreme, we were accused of fraud," recalls biologist Tom Johnson. Fifteen years ago, he and colleague David Friedman, both then at the University of California, Irvine, announced a result that contradicted everything biologists thought they knew about ageing and lifespan. They showed that a change in a single gene was responsible for making nematode worms live up to 65 per cent longer than normal.
 
<del>
 
Scientists have come to accept that simple organisms such as flies and worms possess a simple switch that dictates lifespan. Some are even convinced that this switch works through a handful of molecular signals that affect the rate of ageing.
 
In January this year came an even more surprising result. French researchers revealed that mammals possess a similar switch. They unveiled a single-gene mutation that extends longevity in mice via a molecular pathway similar to the one in the worm. This surprise finding is being hailed as powerful evidence that all animals have a genetic switch that can alter normal lifespan.
 
The idea that lifespan has an inbuilt, genetically controlled flexibility has sparked a spirited debate. Some researchers believe such results fit nicely with existing theories of how and why we age but others argue it will force a major rethink. "It's quite clear that this pathway is regulating the rate of ageing," says Cynthia Kenyon, a geneticist at the University of California, San Francisco, and one of the leaders in the study of the genetics of ageing. What's more, she adds, human intervention could alter this pathway.
 
<del>
 
The main bone of contention is that if genes do control the rate of ageing, they must have somehow evolved for this purpose by natural selection. And for decades, evolutionary biologists were convinced that genes specifically for ageing couldn't have evolved, because the process starts after an organism has successfully reproduced and should therefore lie beyond the reach of natural selection.
 
<del>
 
[It was argued that species where older individuals competed with the young for scarse resoruces were at an evolutionary disadvantage.]
 
<del>
 
 January's big news, from a research team led by Yves Le Bouc at the Institute of Health and Medical Research in Paris, came from experiments on mice in which another insulin-related signalling pathway had been disabled. In this instance it was the insulin-like growth factor-1 (IGF-1) pathway, which regulates many functions including energy metabolism. In the mouse experiments, knocking out the pathway extended average longevity by 33 per cent in females and 16 per cent in males. It looked as though insulin-related pathways were involved in ageing in a mammals, too. "This finding is the most definitive evidence yet that this really is an evolutionarily conserved pathway," says Johnson.
 
[In that case the preceding item is hardly surprising - a diabetes drug extending lifespan.]
 
More on http://archive.newscientist.com/ - paid for subscription required - enter issue 2391, page 26 in the search box. However you can join a 7 days free trial if you have not done so before, and just download this article.
 

27 April
 
Obesity raises risk of death from cancer
 
United Press International--Obesity appears to increase the risk of dying from cancer significantly and could play a role in more than 90,000 deaths from the disease each year in the United States, a study by the American Cancer Society released Wednesday reveals. The study, which looked at hundreds of thousands of people over a 16-year period, found "the heaviest men and women in the study had 50-60 percent higher death rates from cancer than normal-weight people," Jeanne Calle, the principal author of the study and director of analytic epidemiology for the American Cancer Society, told United Press International.
 
Virus Targets Mosquitoes That Carry West Nile

Fight virus with virus, the U.S. Agricultural Research Service (ARS) says, in announcing that its scientists have devised a high-tech way to target mosquitoes that carry the deadly West Nile virus.
 
The ARS says its scientists have received a patent for a baculovirus that targets only the Culex mosquito and doesn't harm other insects, plants, wildlife or people. The baculovirus is activated when mixed with magnesium. When the mixture is added to a body of water where mosquitoes breed, it kills 85 percent to 95 percent of the mosquito larvae after two or three days, the ARS says in a prepared statement. And the magnesium won't harm the water.
 
ARS, the U.S. Department of Agriculture's chief scientific research agency, says it's seeking partners to license the technology.
 
Last year, West Nile killed 277 people in the United States and sickened more than 4,000, according to the U.S. Centers for Disease Control and Prevention.

30 April
 
Mouse mutation fights off cancer
United Press International
 
Scientists said Monday they have developed a strain of genetically altered mice able to successfully fight off virulent cancers, a development they hope will lead to new ways of staving off the disease in humans.
 
Researchers discovered by accident a mouse that had a genetic mutation that enabled it to remain cancer-free even after injections of a cancer cell that normally causes rapid and widespread tumors in mice, Dr. Mark Willingham, a pathologist at Wake Forest University and a co-author of the study, told United Press International.
 
Willingham's team used the mutant mouse to create a colony of about 700 mice that share the cancer-fighting mutation, which may help investigators develop treatments for the disease in humans, he said.
 
The mutation -- which appears to be in a single, as yet unidentified gene -- causes a massive reaction of the mice's white blood cells to cancer cells. The white blood cells, a component of the mice's immune system which helps fight off infections, destroy the cancer cells but leave normal cells alone.
 
Can Dogs Sniff Out Cancer?
 
Dogs are already invaluable for sniffing out illegal drugs and explosives, so why not cancer, British scientists say.
 
Researchers from Cambridge University and Addenbrooke's Hospital have applied to fund a 12-month study on whether canines can detect signs of prostate cancer (news - web sites) in a man's urine, The Western Mail newspaper reports.
 
Dr. Barbara Sommerville, the lead researcher, says existing screening methods aren't always reliable. She adds that men often undergo multiple biopsies only to find out they don't have cancer.
 
If her trial is approved, she plans to use German shepherds and labradors to do the sniffing, the newspaper says.
 
Feasting plus fasting can boost health

United Press International--The results of rodent experiments suggest skipping meals can help people fight diabetes and protect their brain cells, medical researchers at the National Institutes of Health said Monday. "Three meals per day plus snacks, which is the norm in our society, may not be as healthy as a meal-skipping diet," neuroscientist Mark Mattson, at the National Institute of Aging Gerontology Research Center in Baltimore, told United Press International. "Although meal-skipping diets are likely to be safe in healthy mature adults, they may not be beneficial or might even be bad for children and for adults with certain medical conditions," he cautioned.

 

 

Small Print:

For more information about cryonics or Cryonics Institute and how to become a member, visit our web site at http://www.cryonics.org.

We encourage readers to forward issues to friends and interested parties. Please send any suggestions or comments to Long Life by emailing John@...

Long Life would like to thank Longevity Report, Wired News, InfoBeat, The New York Times, The New Scientist, Nanodot, Slashdot, contributors to the Extropian and CryoNet mailing lists, members of the Cryonics Institute, and others, for helping provide some of the free public information used in Long Life.

(Disclaimer: CI does not necessarily encourage or advocate the use of any products or practices mentioned in its newsletter.)

--
Sincerely, John de Rivaz: 
http://John.deRivaz.com for websites including Cryonics Europe, Longevity Report, The Venturists, Porthtowan, Alec Harley Reeves - inventor, Arthur Bowker - potter, de Rivaz genealogy,  Nomad .. and more

#18 From: long_life@yahoogroups.com
Date: Wed Apr 2, 2003 2:39 am
Subject: Poll results for long_life
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The following long_life poll is now closed.  Here are the
final results:


POLL QUESTION: One of our readers has suggested a
contents list for each issue. This
could be done, but as this newsletter
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volunteers over its hopefully long
life, we want to keep it as simple as
possible and requiring as little work
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Do you recommend a contents list for
each issue?

CHOICES AND RESULTS
- Yes, it would be really useful, 7 votes, 46.67%
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#17 From: "John de Rivaz" <John@...>
Date: Mon Mar 31, 2003 4:58 pm
Subject: Long Life 4
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Long Life: the Cryonics Institute newsletter

April 2003 -- Volume 2, Number 4

Welcome to Long Life -- the electronic newsletter of the Cryonics Institute. We're here to update you with brief cutting-edge news, updates, links, and information about the latest scientific, medical, health, anti-ageing, and social developments relevant to CI's goal of saving, preserving, and extending human life. Long Life may also include news about Cryonics Institute events and member activities and opinion. We welcome your feedback, and encourage readers to forward issues to friends and interested parties.


 
CI and general cryonics news:
 
The CI Research Fund has broken the $26,000 mark in terms of raising donations. For further information, click here. At Alcor there is yet another patient, and Charles Platt has been appointed COO (chief operating officer).

Christine Gaspar has definitely been confirmed as President of CSC in Toronto. She's a good pick: there is a contagious and often fatal respiratory illness called SARS running around Toronto, and Christine spent the days prior to the meeting attending to four very bad cases. Brave woman. She attended the meet in a surgical mask, so as not to take the risk of possibly infecting the rest of us. Hopefully it will work. Cryonics Europe was also the subject of much discussion. They seem to be turning out to be the kind of template to which other local response groups are aspiring. Alan Sinclair's manual was singled out for particular praise.

The CSC has a new web site up, authored by the harried David Pascal. It's on their site at www.cryocdn.org. The contents are unchanged, and there is a link to Ben Best’s Cryonics: The Issues on his own site.

The cryonics support group The Venturists are planning a re-launch. The printed newsletter is to be upgraded and issued on a monthly instead of a quarterly basis, and with a colour cover suitable for newsagent distribution. In addition, they are seeking board members from all cryonics organisations to expand their present all Alcor board.

The vote as to whether this newsletter should have a contents list ended in a draw with only 14 votes - 7 for 7 against - out of well over 200 members. It is assumed that those who didn't vote would have voted "it isn't worth the effort" had they cast their votes.

Further information on SARS can be found on CryoNet and Promedmail. If there wasn't a war on, it is likely this would be major news around the world. As it is, humanity's general apathy and refusal to change behaviour even temporarily could make this disease have a place in history alongside the Black Death and the Spanish flu of 1918. -- at least if you believe the postings of Mike Darwin and Charles Platt on CryoNet. I have to say that I have no reason to disbelieve them. I would urge all cryonicists to make themselves aware of this disease, its treatment and avoidance precautions, and then to keep up to speed with developments.

From: WORLDWISE OnLINE and  WORLDWISE Travellers Health Centres
72 Remuera Road, Newmarket, Auckland, NEW ZEALAND   
tel: 09-520-5830 online@...,
web: www.worldwise.co.nz

Date 30 March 2003 - advice may have changed if you read this at a later date.

Prevention of SARS:

Based on investigations so far, the major mode of transmission is by droplet spread when an infected person coughs or sneezes and droplets are spread to a nearby contact. But there is concern about the possibility of airborne transmission across broader areas and also the possibility that fomites could serve as modes of spread. Coronaviruses can survive in the environment for up to 2-3 hours, thus a contaminated object could serve as a vehicle for transfer to someone else. The following are considered helpful in the prevention of the disease;

a) Infection control precautions should be continued for SARS patients for 10 days after respiratory symptoms and fever are gone. SARS patients should limit interactions outside the home and should not go to work, school, out-of-home day care, or other public areas during the 10 day period.

b) During this 10 day period, all members of the household with a SARS patient should carefully follow recommendations for hand hygiene, such as frequent hand washing or the use of alcohol-based rubs.

c) Each patient with SARS should cover his or her mouth and nose with a tissue before sneezing or coughing.

d) If possible, a person recovering from SARS should wear a surgical mask during close contact with uninfected persons.

e) If the patient is unable to wear a surgical mask, other persons in the home should wear masks when in close contact with the patient.

f) Disposable gloves should be considered for any contact with body fluids from a SARS patient. However, immediately after activities involving contact with body fluids, gloves should be removed and discarded and hands should be washed. Gloves should not be reused, and are not intended to replace proper hand hygiene.

g) SARS patients should avoid sharing eating utensils, towels and bedding with other members of the household, although these items can be used by others after routine cleaning such as washing or laundering with soap and hot water.

h) Other members of the household need not restrict their outside activities unless they develop symptoms of SARS such as a fever or respiratory illness.

For the people who are living in the household with the SARS patients, and who are otherwise well, there is no reason to limit activities at this point in time. The experience in the United States has not demonstrated spread of SARS from household contacts into the community and so we are not advising any restrictions on the activity of contacts at this point in time. However, contacts with SARS patients need to be alert to the earliest symptom of a respiratory illness and advise accordingly.


Report on A Tort ou B Raison (Right or Wrong) French TV Channel 1 March 10th 2003

Chrissie de Rivaz < Chrissie@... >

Firstly, my apologies for the delay in sending this report. I have asked several times for the names of the other panel members, largely to present correct spelling of their names. However, as one comes to expect of media folk, the information has not arrived. Nor have I seen the final version of the programme, so am unaware of any editing that took place. No, they didn’t send the promised tape either!

An interesting programme which in total, lasted for 1 hour and 45 minutes. It is largely a series of debates on various topics, interspersed with short pieces of film to illustrate the subject. Presented by Bernard Tapie, an ex-minister of the French Government and now a ‘TV personality’, it addresses any controversial subject which provokes reaction. Interestingly, the first half of the programme was devoted to the problems with the equivalent of the French National Health service and the growing number of apparently untreatable new strains of virus and bacteria.

The second part of the programme was looking at aspects of science which impact on our lives. Cloning, IVF, Cryonics and Bionics were covered, with a variety of experts to head each section. The segment became dominated by an Italian doctor who had a great grievance about coverage of his work by the world press. (He’s the one who worked on IVF with menopausal woman, allowing women of 60+ years to give birth) He could not attend personally and shouted from a studio about how he was a hero and all the French were idiots. The audience yelled back, as one might imagine! It became tedious after a while, as he waved around pictures of (different coloured) cats he claimed were clones and talked of many babies he knew to be cloned. He would not reveal names or locations of course, as this would infringe upon on their liberties. Hopefully, his dominance in the final version of the programme was edited. The debate that followed was led by a French doctor who is working on therapeutic cloning. Of more interest to most of us was his hope to be able to produce replacement organs and other body parts from an individual’s own DNA.

Doctor Pierre Boutron was the specialist cryo-biologist who was speaking about his own work on IVF and the freezing of human embryos. We had a long discussion before the programme, to me more interesting than the final TV input! He was quite adamant that cryonics would never work for humans and expressed the wish that it could be successful. He even said that he would be prepared to take the gamble for himself, if he could afford it. He reiterated his words on air and was clearly never going to listen to anything anyone could say in defence. He is a respected scientist throughout the world and clearly, his words influenced the rest of the panel. They were all very polite, though very sceptical of any outcome. I did point out that they quoted much greater prices than anyone charges, especially when they suggested it was a waste of money. One of the panel suggested that the price was irrelevant if cryonics wouldn’t work anyway! I disagreed and pointed out some of the now common procedures which were once considered impossible, not least the definition of clinical death. They seemed to like the fact that I admitted reanimation was impossible today but we were looking at future technology. It was comforting to see the now familiar snippet of film with Andy Zawacki at C.I., amidst the sceptics. Another piece of film was looking at the tiny creatures, tardigrades, which can be completely de-hydrated for many years and regain viable life when water it reintroduced. The concept was in support of regaining life after reanimation, of course but the other scientists claimed this was somewhat irrelevant compared to cryonics.

The final section of the programme dealt with the use of biologically controlled prosthetics now being developed. I felt it was another relevant item for all our futures as it was looking very much at brain impulses attempting to control movement of limbs in an involuntary manner. Again, a very high powered professor was the spokesman and an acknowledged world expert. He admitted to a very limited success but said that early failures were actually leading to present success. He is optimistic that bionic technology is going to bring help to many people with disabilities on the future.

One interesting discussion I had (off camera) with Dr Boutron was concerning vitrification. Though he agreed that this was a much more likely success potential, he claimed that no perfusate fluids so far developed could possibly work. I did wonder if I’d misunderstood when he said no-one was yet using them. As I pointed out, Alcor are currently using vitrification and have been for some time. Maybe my French isn’t as good as I thought, especially as he said he was in close contact with most of the cryo-biologists working on cryonics. He agreed that it was possible that Dr Pichugin may be on to something but I’m afraid his ‘prejudice’ was just too great for me to compete. A charming, clever man, nonetheless.

It was a good experience, even if I failed to convince anyone. There was some talk after the programme of a full length documentary, at some future point, based exclusively on cryonics and enabling us to give a stronger case without so much opposition. We shall see!

Paris still remains one of the most beautiful cities on the world and I was grateful for the opportunity to speak on behalf of cryonics.


General News Items

Important Note: A lot of these items are from sources designed for public consumption and contain no references or further information. It is up to readers to do their own web searches or whatever for further information.

 

Undated
 
CMOS CHIP WATCHES NEURONS
 
Infineon Technologies disclosed at the International Solid State Circuits Conference that it has altered a 0.5um CMOS process to let it act as a sensor array for neuron cells that can be studied in vitro.
 
Dr Bjoern Eversmann of Infineon's corporate research laboratory, said the requirement from biologists was for a the long-term recording of data from cell cultures.
 
"This tool can provide new insights into neuroscience," he said.
 
According to Eversmann, CMOS was needed to implement large-scale two-dimensional sensor arrays, but with changes to improve the sensitivity of capacitive electrodes on top of the chip.
 
So, once the normal CMOS processing has completed, the sensor layer is patterned with titanium dioxide, a high dielectric-constant material, and passivated with a thin nitride layer. The use of chemical-mechanical polishing provides flat surface for the sensor layer.
 
Able to measure electrical impulses in the region of tens of microvolts, the 128 x 128 sensor arrays can monitor the signals both within neurons and between connected cells. The company is looking to scale down the process to be able to handle smaller retinal cells for eye-nerve research.
 
 

10 March
 
Bio Sensors
 
 
Patients probably won't have to wait until 2020 for new biomedical technology to make its way into their doctor's arsenal. A new class of biosensors--devices that can monitor health conditions and then respond by delivering drugs--no bigger than a jelly bean should be available in five to seven years. Thanks to advances in nanotechnology, microelectromechanical systems, molecular diagnostics, and several other technologies, biosensors are now being developed to detect everything from the first chemical signature of cancer to the presence of anthrax.
 
The technology behind biosensors sounds perfectly simple. Typically, there is a probe on the tip of the sensor that makes contact with blood or tissue. Because of its particular electrical, metallic, and chemical composition, the sensor is able to "react" in a tell-tale manner when it comes into contact with the target. That reaction is then magnified, quantified, illuminated with various stains and dyes, and then matched against the ever-expanding libraries of gene sequences and protein structures of diseases.
 

 
11 March
 
After nearly four years of searching for extraterrestrial intelligence, the SETI@home project will now take a closer look at its most promising candidate radio sources.  The "Stellar Countdown" will use Puerto Rico's Arecibo radio telescope on March 18-20, 2003 to re-observe up to 150 of the most interesting radio sources found out of the billions detected since the distributed computing project began in May 1999. Visit http://planetary.org/stellarcountdown/ to read daily updates from the Arecibo research team during the Stellar Countdown. 
 
Some years ago it was suggested in The Immortalist in a series of articles such as this one or this one that the first thing ET will want to tell us is how to be immortal, because that way they will suppress humanity's urges to make war.
 
Austrian Doctors Perform World's First Double-Arm Transplant

HealthScout News--Doctors in Austria have performed the world's first double-arm transplant. A 41-year-old man received a pair of forearms and hands in a 14-hour operation on Feb. 19. The man lost his forearms and hands in a work accident more than two years ago, BBC News Online reports. The operation at Innsbruck University Clinic required four surgical teams and 25 experts. The operation had been planned for months, while the medical team waited for a donor. The transplant recipient said that he is feeling well and that the new hands feel as if they are his own.
 
Drug-Resistant Germs on the Rise
 
By July 2004, nearly two-thirds of the common strains of the bacteria that cause infections ranging from middle ear problems to meningitis may be resistant to both penicillin and erythromycin in some parts of the United States.
 
At least that's what Harvard University researchers believe.
 
In a study published in the March 10 issue of Nature Medicine, the scientists used a mathematical model to predict how certain antibiotic-resistant strains of Streptococcus pneumoniae would develop.
 
Overall, they found that 41 percent of S. pneumoniae would be resistant to penicillin and erythromycin if no changes occur in the way antibiotics are used in the eight sites studied across the United States. At a site in Tennesse, the resistance figure is already approaching 80 percent, the researchers say.
 
Much of the problem is due to inappropriate use of antibiotics for sicknesses that don't respond to the drugs, such as the common cold and other viral infections.

12 March
 
LASIK surgery can cause double vision
United Press International
 
Vision-correcting LASIK surgery can cause double vision, but this problem can be minimized if ophthalmologists exclude people with certain eye conditions from undergoing the procedure, two eye experts said in a study released Monday.
 
"People who have a history (of particular eye disorders) are at higher risk, and they should call that to the attention of their doctor," Dr. Burton Kushner, an ophthalmologist at the University of Wisconsin in Madison and lead author on the study, told United Press International.
 
The patients also should ask if they are likely to have double vision after the surgery, Kushner said. "That should raise the red flag for the doctor to do appropriate testing to determine if they are at risk for it," he said.
Vinegar Can Help Identify Cervical Cancer
World Entertainment News Network
 
Research carried out in South Africa has found that washing the cervix or neck of the womb with vinegar shows up potentially cancerous cells.
 
An early trial has suggested the technique is as effective as a pap smear, which is the more usual way of spotting the disease. Doctors believe their research could pave the way for developing countries to introduce a cheap and effective screening programme for cervical cancer. Vinegar comprises water and 5 per cent acetic acid. When this solution is placed on the cervix, it turns potentially cancerous tissue white. This enables nurses to offer patients an immediate diagnosis by simply looking at the cervix. This compares with a pap smear which usually needs to be sent off to a laboratory for testing.
 

 
March 13
 
Healthy Breakfast Is Any Breakfast
 
World Entertainment News Network--Even people who eat sugar laden cereal or fat ridden fried breakfasts are doing better than people who skip straight out of the door, according to a new survey. Those who say they regularly eat breakfast are less likely to develop problems such as diabetes or become obese than people who report typically rushing out the door on an empty stomach, the new study shows. Breakfast eaters are up to 55 per cent less likely to have problems with insulin resistance or become obese than their non-breakfasting counterparts, the research suggests.
 
Coffee, hormones affect Parkinson's risk

United Press International
 
Women who are heavy coffee drinkers and take hormone replacement therapy could be at a higher risk for developing Parkinson's disease, research released Tuesday suggested.
 
For women who take HRT and drink beverages with little or no caffeine, the risk was reduced, according to the study published in the journal of the American Academy of Neurology.
 
Although previous studies have associated caffeine with a low risk for Parkinson's in men, data on women have been inconclusive. Dr. Alberto Ascherio's research suggests the ambiguity could be due to a previously unknown hormone factor.
 

 
14 March
 
Common painkillers may thwart Alzheimer's
 
United Press International
 
Researchers reported Wednesday common pain killers such as ibuprofen could dissolve the cell-strangling build-up of a brain protein that characterizes Alzheimer's disease, possibly thwarting progression of the mind-wasting disorder that exacts a hefty emotional and economic price.
 
Investigators at the University of California, Los Angeles, found some of the over-the-counter medications, known as non-steroidal anti-inflammatory drugs, might whittle away the deranging and deadly deposits of excess amyloid protein in the brain and prevent the formation of new ones.
 
The toxic plaques -- which stifle nerve cells' ability to communicate with each other, causing them to die -- are a definitive hallmark of Alzheimer's.
 
[The Life Extension Foundation have been saying this for years]

Are we alone? We might know soon

United Press International
 
One of the greatest questions of all -- Are we alone in the universe? -- might be answered starting next week as scientists point a giant radiotelescope at some of the most promising candidates in our galaxy for possible homes for extraterrestrial intelligence.
 
"This is the culmination of four years of work on the world's largest supercomputer," Dan Werthimer, chief scientist of the SETI at Home project at the University of California, Berkeley, told United Press International.
 
By "supercomputer," Werthimer meant SETI at Home has programmed about 4.3 million desktop computers in 226 countries to analyze data received by Puerto Rico's Arecibo radiotelescope when those computers are on, but not in use.
 
Each computer analyzes a different set of incoming radio noise, looking for patterns scientists would expect from a technologically advanced civilization in another solar system.
 
"We are going to look at the candidates where the signal repeats when you return the telescope to the target," said Werthimer, "and where the signal gets stronger as you approach the star. We've been sifting through the interesting results, looking for the most promising signals."
 
Werthimer and two other scientists plan to visit the Arecibo facility on March 16 to prepare to target 150 candidate signals on March 18-20.
 

15 March
 
New germ-killers from crystal ball scars?

United Press International
 
By peering at crystalline spheres the size of white blood cells, an international team of scientists reported a major breakthrough Thursday in cracking a nearly 100-year-old puzzle, possibly leading to new micro-machines and disease-fighting weapons.
 
The scientists examined microscopic scars marring the surfaces of the spheres and found the infinitesimal imperfections could be the equivalent of "chinks in the armor" of dangerous germs, researcher Mark Bowick at Syracuse University told United Press International.
 
The scars also could help provide crucial nooks and crannies for molecules that enhance microcapsules already under development "to deliver a perfume, a drug for genetic engineering, or anything," Bowick said.
 
Ageing research sees the light at the end of the tunnel.
 
According to this week’s issue of Science Magazine, anti-ageing researchers now see “the light at the end of the tunnel” after more than 20 years of relentless work in many fields.
 
 
I want to be robot not fallible human - Professor Kevin Warwick

WE’VE all seen films like The Terminator, The Matrix and Robocop in which cyborgs - part human, part machine - exhibit their super powers over humans. But surely this is all science fiction, something from Hollywood, and not anything we need bother ourselves about in real life? Well, be warned, the cyborgs are coming - and you can be one too! 
 
In August 1998, Professor Warwick journeyed on his own first adventure - by having a silicon chip transponder surgically implanted in his left arm. With this in place, a computer was able to monitor his movements around a building. It opened doors for him, switched on lights and even gave him a welcoming "hello" when he entered.
 

 
18 March
 
FDA rules could improve patient safety
United Press International
 
The Food and Drug Administration unveiled two proposed rules Thursday the agency said "are the start of a comprehensive strategy to build a medical patient protection system for the 21st century."
 
The first would require bar codes on certain drug labels and the second would clarify existing guidelines drug makers must follow to report adverse effects of their products.
 
FDA said the proposals are in line with a 1999 Institute of Medicine report that cited bar codes as one method that could prevent deaths attributed to medication errors, which seemed to be on the rise. The institute estimated 44,000 to 98,000 deaths occurred per year i