One area worth mentioning is the problem of false positive results from bad practices in academia (error, data mining, publication bias, etc) leading to waste...
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Dario Amodei
damodei@...
Oct 12, 2012 12:40 am
I agree strongly on the importance of systematically reproducing results (see this: http://www.nature.com/nbt/journal/v30/n9/pdf/nbt.2335.pdf, which I recently...
333
Holden Karnofsky
holden0@...
Oct 12, 2012 12:43 am
Carl, thanks for the thoughts & links. We agree that this is a potentially promising area of inquiry. We consider it to fall under the heading of ...
334
Gwern Branwen
gwernbranwen
Oct 12, 2012 2:10 am
On Thu, Oct 11, 2012 at 8:04 PM, Carl M. Shulman ... If anyone is curious, I stash most of my relevant quotes/links/citations in ...
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aubrey.degrey
Oct 12, 2012 11:35 am
Hi everyone, My attention was brought to this thread, by virtue of the fact that it was my work that gave rise to SENS Foundation, and I'm looking forward to...
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Holden Karnofsky
holden0@...
Oct 12, 2012 2:29 pm
Hi Aubrey, Thanks for the thoughts. The NIH appears to have a division focused on research relevant to this topic: http://www.nia.nih.gov/research/dab . Its...
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Aubrey de Grey
aubrey.degrey
Oct 13, 2012 11:17 am
Hi Holden - many thanks. First: yes, there are really three somewhat separate questions for someone trying to evaluate whether to support SENS Foundation: 1)...
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Holden Karnofsky
holden0@...
Oct 13, 2012 4:50 pm
Hi Aubrey, Thanks again for engaging so thoughtfully. I agree that a new technology/treatment that could delay or reverse aging (or aspects of it) would be...
339
Aubrey de Grey
aubrey.degrey
Oct 13, 2012 5:12 pm
Excellent. I too am keen to see Dario's comments. Dario also has the advantage of being based just a few miles from SENS Foundation's research centre, so we...
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Susheela Peres da Costa
susheela.peresdacosta...
Oct 15, 2012 2:46 am
Aubrey, I would love to hear more about two things you raise as worthwhile questions. 1) The distinction between longevity on the one hand and the postponement...
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Susheela Peres da Costa
susheela.peresdacosta...
Oct 15, 2012 3:10 am
sorry, realise a sentence wasn't finished, amended below On 15 October 2012 12:43, Susheela Peres da Costa < ... sorry, realise a sentence wasn't finished,...
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Aubrey de Grey
aubrey.degrey
Oct 15, 2012 7:00 pm
Hello Susheela, Yes, I expected that some people here would be interested in discussing these topics, even if Holden't focus is currently more on whom best to...
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Brian Douglas Skinner
briandouglas...
Oct 30, 2012 12:46 am
Hi Aubrey, Thanks for the detailed answer to Holden's question about the differences between what the NIA is doing and what the SENS Foundation is doing. If...
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Aubrey de Grey
aubrey.degrey
Oct 30, 2012 1:56 pm
Hello Brian, Thanks for this question. In brief, the main differences between SENS Foundation and the Buck are quite similar to those between SENS Foundation...
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Brian Douglas Skinner
briandouglas...
Oct 30, 2012 6:26 pm
Hi Aubrey, Thanks for the quick response. That gives me a better understanding for where the Buck Institute fits in the landscape of organizations. Best, Brian...
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Aaron Swartz
me@...
Nov 14, 2012 7:46 pm
In GiveWell's recent update about SCI, they write<http://www.givewell.org/international/top-charities/schistosomiasis-control-initiative/updates/November-2012>...
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Holly Morgan
lady_morgana_02
Nov 14, 2012 8:22 pm
Perhaps the person who gave the figure in £s had received it in $s from someone else, and this latter person had made the typo? -- Please excuse brevity; this...
348
martajbornstein3
martajbornst...
Nov 14, 2012 10:17 pm
I realize this mailing list isn't for sharing content from subscribers, but I thought this article published by GOOD Magazine on Monday is especially relevant...
349
rnoble@...
Nov 14, 2012 11:18 pm
I had wondered if there is reluctance to communicate with GiveWell because GiveWell may have developed a reputation for being harsh on charities. I'm not...
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Ben Hoskin
ben.hoskin@...
Nov 15, 2012 12:50 am
A similar thing occurs with public companies in immature markets becoming very emotional about stockbrokers, often completely shutting them out after a 'sell'...
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Natalie Stone Crispin
nstone3
Nov 15, 2012 8:05 pm
Hi Holly, SCI provided the spending figure to us in pounds (£1,329), and we converted these to the dollar figure that we then asked SCI about ($2,100). The ...
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Holly Morgan
lady_morgana_02
Nov 15, 2012 8:28 pm
Ah fair enough, thanks Natalie -- Please excuse brevity; this message has been sent from my mobile phone. Holly Morgan | Executive Director | The Life You Can...
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Holden Karnofsky
holden0@...
Nov 15, 2012 8:32 pm
Hi all, thanks for the thoughts. A few responses: 1. We really appreciate Aaron's raising this concern. In general, we encourage people to raise any issues...
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Alexander Berger
albrgr
Dec 17, 2012 6:20 pm
A donor recently emailed us asking about the changes in our cost-effectiveness estimates for AMF. The donor pointed out that our estimate had changed and...
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Alexander Berger
albrgr
Dec 28, 2012 12:52 am
We thought this exchange about our shift away from emphasizing the "standouts" list might be of some general interest: Vipul Naik wrote to us, asking: Dear...
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Ian David Moss
crazynewmusic
Dec 30, 2012 5:20 pm
Hi guys, On a related note, I'm getting ready to donate to GW's recommended charities and have been thinking a bit about VillageReach. In your July 26 blog...
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Elie Hassenfeld
elie@...
Dec 31, 2012 3:28 am
Hi Ian, We have continued to follow VillageReach and did consider potentially recommending funding for them for the sake of "transparency incentives." I don't...
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Ian David Moss
mossinator@...
Dec 31, 2012 4:16 am
Thanks, Elie, I appreciate the response. I am curious, though, about why you decided against recommending for the sake of transparency. Was there new...
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Elie Hassenfeld
elie@...
Dec 31, 2012 4:40 am
Hi Ian, It was more that transparency incentives in general were not a good enough reason to recommend funding. -Elie ... Hi Ian, It was more that transparency...
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Alexander Berger
aberger0527
Feb 27, 2013 12:37 am
Hi folks, Evan Larson, a Princeton student-journalist, is interested in some details of GiveWell's trip to India. We've tried to answer his questions briefly ...
